http://togogenome.org/gene/13146:LOC101871860 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2E8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the PMP-22/EMP/MP20 family.|||Cell membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Membrane raft|||Nucleus|||perinuclear region http://togogenome.org/gene/13146:LOC101869345 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKV8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane|||Probable fucosyltransferase. http://togogenome.org/gene/13146:LOC101876924 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101870945 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KBTBD8 family.|||Golgi apparatus|||spindle http://togogenome.org/gene/13146:LOC101880686 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHH1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family. http://togogenome.org/gene/13146:LOC101880201 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3S5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFB5 family.|||Component of the 7-subunit TFIIH core complex.|||In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.|||Nucleus http://togogenome.org/gene/13146:LOC101881540 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8J6 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101877164 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLH1 ^@ Function|||Similarity ^@ Belongs to the phytoene/squalene synthase family.|||Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. http://togogenome.org/gene/13146:LOC101876377 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/13146:LOC101874793 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4Z3 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/13146:LOC101878657 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5V3 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus http://togogenome.org/gene/13146:LOC101877211 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Nudix hydrolase family. NudC subfamily.|||Cytoplasmic granule|||Peroxisome http://togogenome.org/gene/13146:LOC101873187 ^@ http://purl.uniprot.org/uniprot/A0A8C6J565 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAPTM4/LAPTM5 transporter family.|||Cell membrane|||Endomembrane system|||Endosome membrane|||Late endosome membrane|||Membrane|||multivesicular body lumen|||multivesicular body membrane http://togogenome.org/gene/13146:LOC101878859 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVJ6 ^@ Similarity|||Subunit ^@ Homohexamer.|||In the C-terminal section; belongs to the NAD synthetase family. http://togogenome.org/gene/13146:LOC101870498 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL61 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101873908 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEK1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101881534 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRI6 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the augurin family.|||Cytoplasm|||Membrane|||Secreted http://togogenome.org/gene/13146:LOC101871920 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7P3 ^@ Subcellular Location Annotation ^@ PML body|||autophagosome|||cytosol http://togogenome.org/gene/13146:LOC101879816 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJX4 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/13146:LOC101877761 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868033 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHH9 ^@ Similarity ^@ Belongs to the FHIP family. http://togogenome.org/gene/13146:LOC101880018 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFI1 ^@ Function|||Similarity ^@ Belongs to the ATPase F chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. http://togogenome.org/gene/13146:LOC101869715 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCL9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/13146:LOC101873473 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101870740 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMC9|||http://purl.uniprot.org/uniprot/A0A8C6NDN6 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. http://togogenome.org/gene/13146:LOC101880707 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protease inhibitor I35 (TIMP) family.|||extracellular matrix http://togogenome.org/gene/13146:LOC101869995 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILG5 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/13146:LOC101879400 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDK7 ^@ Similarity ^@ Belongs to the FAM72 family. http://togogenome.org/gene/13146:LOC101874420 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBL1 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/13146:LOC101881231 ^@ http://purl.uniprot.org/uniprot/A0A8C6K576 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101868534 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV39 ^@ Similarity ^@ Belongs to the calreticulin family. http://togogenome.org/gene/13146:LOC101881692 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.|||Endoplasmic reticulum membrane|||Required for N-linked oligosaccharide assembly. http://togogenome.org/gene/13146:LOC101880008 ^@ http://purl.uniprot.org/uniprot/A0A8C6J995 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101876484 ^@ http://purl.uniprot.org/uniprot/A0A8C6J354 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/13146:LOC101877683 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus|||Transcription factor. http://togogenome.org/gene/13146:LOC101875811 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQX0 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/13146:LOC101870818 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBQ3 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101867749 ^@ http://purl.uniprot.org/uniprot/A0A8C6K400 ^@ Subcellular Location Annotation ^@ cytoskeleton|||sarcomere http://togogenome.org/gene/13146:LOC101877524 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU24 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101870787 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3M3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||cilium basal body http://togogenome.org/gene/13146:LOC101868487 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tollip family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101869050 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.|||Membrane|||Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. http://togogenome.org/gene/13146:LOC101871427 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||synaptosome http://togogenome.org/gene/13146:LOC101881518 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKL3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 47 family. http://togogenome.org/gene/13146:LOC101874599 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCZ5 ^@ Similarity ^@ Belongs to the potassium channel KCNE family. http://togogenome.org/gene/13146:LOC101877579 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ93 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPCAM family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101869748 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHW5 ^@ Similarity ^@ Belongs to the PAIP2 family. http://togogenome.org/gene/13146:LOC101880624 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFL2 ^@ Function|||Similarity ^@ Belongs to the PIGL family.|||Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol. http://togogenome.org/gene/13146:LOC101869034 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAM7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase e1/e2 subunit family.|||Membrane|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101870668 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR02 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tenascin family. Teneurin subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101872914 ^@ http://purl.uniprot.org/uniprot/A0A8C6INF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101869482 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND73 ^@ Function ^@ Converts big endothelin-1 to endothelin-1. http://togogenome.org/gene/13146:LOC101877615 ^@ http://purl.uniprot.org/uniprot/A0A8C6J457 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/13146:LOC101879743 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DUOXA family.|||Membrane http://togogenome.org/gene/13146:LOC101868235 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCU2 ^@ Function|||Similarity ^@ Belongs to the transaldolase family. Type 1 subfamily.|||Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate. http://togogenome.org/gene/13146:LOC101871077 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ47 ^@ Similarity ^@ Belongs to the G-alpha family. G(s) subfamily. http://togogenome.org/gene/13146:LOC101872612 ^@ http://purl.uniprot.org/uniprot/A0A8C6J343 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XPO2/CSE1 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101881271 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ88 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fibrillin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101875802 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101875589 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||Cell membrane http://togogenome.org/gene/13146:LOC101868652 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBR7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101881363 ^@ http://purl.uniprot.org/uniprot/A0A8C6N707 ^@ Similarity ^@ Belongs to the STXBP/unc-18/SEC1 family. http://togogenome.org/gene/13146:LOC101873111 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2C9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101877624 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF51 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the diacylglycerol acyltransferase family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101870398 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYE1 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/13146:LOC101867636 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG05 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||caveola|||sarcolemma http://togogenome.org/gene/13146:LOC101875927 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane|||Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. http://togogenome.org/gene/13146:LOC101868041 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3D8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101880011 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101880483 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2S5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GrpE family.|||Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101873723 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. http://togogenome.org/gene/13146:LOC101870045 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC27 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/13146:LOC101880439 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU72|||http://purl.uniprot.org/uniprot/A0A8C6JUH4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868723 ^@ http://purl.uniprot.org/uniprot/A0A8C6J982 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.|||Cytoplasm http://togogenome.org/gene/13146:LOC101867921 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.|||centrosome http://togogenome.org/gene/13146:LOC101876201 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1M1 ^@ Similarity ^@ Belongs to the UPF0547 family. http://togogenome.org/gene/13146:LOC101869965 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJN2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101874092 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3G2 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/13146:LOC101871940 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5P3 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/13146:LOC101870635 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mis12 family.|||kinetochore http://togogenome.org/gene/13146:LOC101872767 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBC0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101872382 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCS5 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/13146:LOC101881367 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1G9 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101873602 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8V7 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101873825 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAA0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/13146:LOC101870619 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8B7 ^@ Similarity ^@ Belongs to the RTRAF family. http://togogenome.org/gene/13146:LOC101880123 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR02 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/13146:LOC101874767 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSQ5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101868190 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM57 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101873579 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS64 ^@ Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily. http://togogenome.org/gene/13146:LOC101880231 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUF8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/13146:LOC101878295 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN05 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/13146:LOC101869541 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family. ARP5 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101872142 ^@ http://purl.uniprot.org/uniprot/A0A8C6K827 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868672 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU71 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/13146:LOC101879712 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/13146:LOC101879049 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the selenium-binding protein family.|||Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.|||Membrane|||Nucleus|||cytosol http://togogenome.org/gene/13146:LOC101876274 ^@ http://purl.uniprot.org/uniprot/A0A8C6J246 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/13146:LOC101873357 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP18 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL30 family. http://togogenome.org/gene/13146:LOC101872367 ^@ http://purl.uniprot.org/uniprot/I1Y915 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/13146:LOC101880844 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY75 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MDM2/MDM4 family.|||Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.|||Nucleus http://togogenome.org/gene/13146:LOC101879071 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRW1 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/13146:LOC101876632 ^@ http://purl.uniprot.org/uniprot/A0A8C6INE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Homodimer.|||cytosol http://togogenome.org/gene/13146:LOC101872549 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101873184 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/13146:LOC101872251 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHP5 ^@ Similarity ^@ Belongs to the GIPC family. http://togogenome.org/gene/13146:LOC101877860 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||Homodimer.|||May play a role in vesicular transport from endoplasmic reticulum to Golgi.|||cis-Golgi network http://togogenome.org/gene/13146:LOC101868600 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWZ5 ^@ Similarity ^@ Belongs to the HSBP1 family. http://togogenome.org/gene/13146:LOC101870846 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HSF family.|||Nucleus http://togogenome.org/gene/13146:LOC101871331 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBK6 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/13146:LOC101872819 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMZ8 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.|||Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.|||extracellular space|||nucleoplasm|||sarcolemma http://togogenome.org/gene/13146:LOC101875087 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAY5 ^@ Similarity ^@ Belongs to the peptidase C69 family. Secernin subfamily. http://togogenome.org/gene/13146:LOC101872109 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UIF family.|||Nucleus speckle http://togogenome.org/gene/13146:LOC101876000 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC23 subfamily.|||COPII-coated vesicle membrane|||Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/13146:LOC101871610 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEN9 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/13146:LOC101881192 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0A6 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/13146:LOC101874323 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101881200 ^@ http://purl.uniprot.org/uniprot/A0A8C6INT2|||http://purl.uniprot.org/uniprot/A0A8C6IS49 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/13146:LOC101880131 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVA9 ^@ Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family. http://togogenome.org/gene/13146:LOC101875764 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXT0 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/13146:LOC101871177 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7W6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/13146:LOC101868291 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBN2 ^@ Similarity ^@ Belongs to the glycerophosphoryl diester phosphodiesterase family. http://togogenome.org/gene/13146:LOC101876469 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the geminin family.|||Nucleus http://togogenome.org/gene/13146:LOC101881547 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR84 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/13146:LOC101867917 ^@ http://purl.uniprot.org/uniprot/A0A8C6K595 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869001 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUA2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877298 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the opioid neuropeptide precursor family.|||Secreted http://togogenome.org/gene/13146:LOC101875088 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/13146:LOC101870352 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M14 family.|||Secreted http://togogenome.org/gene/13146:LOC101876177 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8F8 ^@ Similarity ^@ Belongs to the SKP1 family. http://togogenome.org/gene/13146:LOC101870872 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879583 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0H1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Sarcoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101870613 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZQ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Belongs to the eIF-3 subunit M family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868495 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872089 ^@ http://purl.uniprot.org/uniprot/A0A8C6J663 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP298 family.|||cilium basal body http://togogenome.org/gene/13146:LOC101880475 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 27 family.|||Nucleus http://togogenome.org/gene/13146:LOC101869390 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITP5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101875833 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI98 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the gemin-2 family.|||Cytoplasm|||Part of the core SMN complex.|||The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. http://togogenome.org/gene/13146:LOC101876321 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM192 family.|||Late endosome|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101870497 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM40 ^@ Function ^@ May be involved in neurite outgrowth. http://togogenome.org/gene/13146:LOC101873095 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVR7 ^@ Function|||Subcellular Location Annotation ^@ Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.|||perinuclear region http://togogenome.org/gene/13146:LOC101881435 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB20 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/13146:LOC101876494 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDPGP type 1 family.|||Homooctamer.|||UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. http://togogenome.org/gene/13146:LOC101870504 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 23 family.|||Secreted http://togogenome.org/gene/13146:LOC101871878 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLR6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/13146:LOC101874117 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5G5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS5 family. http://togogenome.org/gene/13146:LOC101879460 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intermediate filament family.|||axon|||cytoskeleton http://togogenome.org/gene/13146:LOC101871380 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.|||Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.|||extracellular matrix http://togogenome.org/gene/13146:LOC101870323 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPY2 ^@ Similarity ^@ Belongs to the eukaryotic diacylglycerol kinase family. http://togogenome.org/gene/13146:LOC101872946 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pICln (TC 1.A.47) family.|||Nucleus http://togogenome.org/gene/13146:LOC101875494 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. RsmH family. http://togogenome.org/gene/13146:LOC101872467 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mS33 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101867707 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2H5 ^@ Caution|||Function|||Subunit ^@ Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101875142 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5G2 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/13146:LOC101880696 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101867918 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN59 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family. http://togogenome.org/gene/13146:LOC101875560 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1T7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.|||Secreted http://togogenome.org/gene/13146:LOC101879474 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.|||Cell membrane|||Early endosome membrane|||Endoplasmic reticulum membrane|||Endosome membrane|||Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.|||Recycling endosome membrane http://togogenome.org/gene/13146:LOC101871752 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE75 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101879106 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEX7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870013 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV40 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/13146:LOC101874845 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868244 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGT0 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/13146:LOC101868200 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.|||Homohexamer.|||Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. http://togogenome.org/gene/13146:LOC101875086 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1B9|||http://purl.uniprot.org/uniprot/A0A8C6N9G1 ^@ Function|||Similarity ^@ Belongs to the EXO70 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. http://togogenome.org/gene/13146:LOC101880499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/13146:LOC101868540 ^@ http://purl.uniprot.org/uniprot/A0A8C6N664 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101877978 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane|||synaptic vesicle membrane http://togogenome.org/gene/13146:LOC101874474 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMP-30/CGR1 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101872801 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCH7 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/13146:LOC101872714 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/13146:LOC101880755 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.|||Cell projection|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101870903 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTY6 ^@ Similarity ^@ Belongs to the GST superfamily. Alpha family. http://togogenome.org/gene/13146:LOC101873529 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.|||Sarcoplasmic reticulum|||sarcomere http://togogenome.org/gene/13146:LOC101872802 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCC7 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101868196 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.|||Belongs to the tumor necrosis factor family.|||Cell surface|||Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.|||Homotrimer. http://togogenome.org/gene/13146:LOC101871886 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH20 ^@ Similarity|||Subunit ^@ Belongs to the histone H3 family.|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101879794 ^@ http://purl.uniprot.org/uniprot/A0A8C6J627 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM43 family.|||Membrane http://togogenome.org/gene/13146:AOX2 ^@ http://purl.uniprot.org/uniprot/M1ZMM5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xanthine dehydrogenase family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Binds 2 [2Fe-2S] clusters.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/13146:LOC101881671 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6J4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101867937 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWI8 ^@ Subcellular Location Annotation|||Subunit ^@ Efficient DNA binding requires dimerization with another bHLH protein.|||Nucleus http://togogenome.org/gene/13146:LOC101878564 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMM6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the noggin family.|||Homodimer.|||Secreted http://togogenome.org/gene/13146:LOC101878197 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUL9 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/13146:LOC101871095 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin conjugation factor E4 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101877508 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868928 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSX3 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/13146:LOC101877268 ^@ http://purl.uniprot.org/uniprot/A0A8C6K343 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Component of the 40S small ribosomal subunit.|||Rough endoplasmic reticulum http://togogenome.org/gene/13146:LOC101880573 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2Q4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family. http://togogenome.org/gene/13146:LOC101874126 ^@ http://purl.uniprot.org/uniprot/A0A8C6N996 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/13146:LOC101872796 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM56 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/13146:LOC101873395 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101874643 ^@ http://purl.uniprot.org/uniprot/A0A8C6J686|||http://purl.uniprot.org/uniprot/A0A8C6J9F0 ^@ Similarity ^@ Belongs to the SEC3 family. http://togogenome.org/gene/13146:LOC101871180 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CNRIP family.|||Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.|||Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. http://togogenome.org/gene/13146:LOC101874357 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC59 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/13146:LOC101873659 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCL1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the plexin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101872638 ^@ http://purl.uniprot.org/uniprot/A0A8C6JID0 ^@ Function|||Similarity ^@ Belongs to the MnmG family.|||Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs. http://togogenome.org/gene/13146:LOC101874648 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFS4 ^@ Similarity ^@ Belongs to the WD repeat CDC20/Fizzy family. http://togogenome.org/gene/13146:LOC101871525 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC1 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Nucleus|||ORC is composed of six subunits. http://togogenome.org/gene/13146:LOC101873746 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGJ8|||http://purl.uniprot.org/uniprot/A0A8C6JI28|||http://purl.uniprot.org/uniprot/A0A8C6JK59 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/13146:LOC101881883 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLH4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic-type primase large subunit family.|||Binds 1 [4Fe-4S] cluster.|||Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. http://togogenome.org/gene/13146:LOC101880430 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ENY2 family.|||Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2). Component of the SAGA transcription coactivator-HAT complex. Within the SAGA complex, participates to a subcomplex of SAGA called the DUB module (deubiquitination module).|||Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.|||nucleoplasm http://togogenome.org/gene/13146:LOC101875492 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7B2 ^@ Similarity|||Subunit ^@ Homodimer.|||In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.|||In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family. http://togogenome.org/gene/13146:LOC101877371 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7K9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/13146:LOC106023410 ^@ http://purl.uniprot.org/uniprot/A0A8C6J512 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/13146:LOC101875221 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMY3 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101869490 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NKAIN family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101878794 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6F5 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/13146:LOC101869603 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Heterodimer with RPLP1 at the lateral ribosomal stalk of the large ribosomal subunit.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/13146:LOC101875239 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Q1 ^@ Similarity ^@ Belongs to the paralemmin family. http://togogenome.org/gene/13146:LOC101878819 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 8 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/13146:LOC101881208 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3M2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/13146:LOC101880953 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCT0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TUBGCP family.|||Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.|||centrosome http://togogenome.org/gene/13146:LOC101874997 ^@ http://purl.uniprot.org/uniprot/A0A8C6J196 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC43A transporter (TC 2.A.1.44) family.|||Membrane http://togogenome.org/gene/13146:LOC101871634 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWR3 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868500 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8D4 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/13146:LOC101869272 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYR8 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101879874 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ32 ^@ Similarity ^@ Belongs to the TOM1 family. http://togogenome.org/gene/13146:LOC101875083 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.|||Nucleus|||centromere http://togogenome.org/gene/13146:LOC101873025 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWI4 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/13146:LOC101869896 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR79 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. http://togogenome.org/gene/13146:LOC101876165 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKB4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101879935 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/13146:LOC101880239 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP5/NOP56 family.|||nucleolus http://togogenome.org/gene/13146:LOC101881925 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVM4 ^@ Similarity ^@ Belongs to the P-Pant transferase superfamily. AcpS family. http://togogenome.org/gene/13146:LOC101879111 ^@ http://purl.uniprot.org/uniprot/A0A8C6N860 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101870442 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.|||Nucleus http://togogenome.org/gene/13146:LOC101873565 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase VIIb family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101867756 ^@ http://purl.uniprot.org/uniprot/A0A8C6K8D7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/13146:LOC101873252 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101874310 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPSB family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868199 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCJ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS1 family.|||Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).|||Cytoplasm http://togogenome.org/gene/13146:LOC101870948 ^@ http://purl.uniprot.org/uniprot/A0A8C6N836 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101869778 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874164 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad17/RAD24 family.|||Nucleus http://togogenome.org/gene/13146:LOC101872541 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDT3 ^@ Similarity ^@ Belongs to the WD repeat coronin family. http://togogenome.org/gene/13146:LOC101881643 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP02 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101876700 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBG5 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/13146:LOC101880013 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RAD23 family.|||Cytoplasm|||Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.|||Nucleus http://togogenome.org/gene/13146:LOC101876173 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871108 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.|||extracellular matrix http://togogenome.org/gene/13146:LOC101871008 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAE8 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/13146:LOC101873891 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE81 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/13146:LOC101868405 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869286 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKZ8|||http://purl.uniprot.org/uniprot/A0A8C6IMW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/13146:LOC101874236 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Y4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||basement membrane http://togogenome.org/gene/13146:LOC101873593 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXF4 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/13146:LOC101876725 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV76 ^@ Similarity ^@ Belongs to the STEEP1 family. http://togogenome.org/gene/13146:LOC101880965 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101873462 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101879180 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ72 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 1 family.|||Binds 1 zinc ion per subunit.|||Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions. http://togogenome.org/gene/13146:LOC101876783 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9Q7 ^@ Similarity ^@ Belongs to the neuritin family. http://togogenome.org/gene/13146:LOC101881312 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101875859 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJG5 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101871226 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane|||Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. http://togogenome.org/gene/13146:LOC101869587 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREG family.|||Secreted http://togogenome.org/gene/13146:LOC101874130 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EBP2 family.|||Required for the processing of the 27S pre-rRNA.|||nucleolus http://togogenome.org/gene/13146:LOC101872473 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9U2 ^@ Similarity ^@ Belongs to the WAPL family. http://togogenome.org/gene/13146:LOC101872166 ^@ http://purl.uniprot.org/uniprot/A0A8C6J077 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101877816 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDR8 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101878575 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUT2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101878303 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC50/LEM3 family.|||Cell membrane|||Golgi apparatus|||Membrane|||secretory vesicle membrane http://togogenome.org/gene/13146:LOC101877891 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleoporin Nup133 family.|||nuclear pore complex http://togogenome.org/gene/13146:LOC101868660 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUL3 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Endosome membrane|||Nucleus|||phagosome|||ruffle http://togogenome.org/gene/13146:LOC101879497 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1P1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the R-spondin family.|||Secreted http://togogenome.org/gene/13146:LOC101868623 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.|||Belongs to the NMD3 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101870591 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101869184 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDK2 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/13146:LOC101870202 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXN4 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101871482 ^@ http://purl.uniprot.org/uniprot/A0A8C6J150 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/13146:LOC101870487 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEP3 ^@ Similarity ^@ Belongs to the 2-5A synthase family. http://togogenome.org/gene/13146:LOC101874905 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPN9 ^@ Similarity ^@ Belongs to the RRM CPEB family. http://togogenome.org/gene/13146:LOC101878822 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNX2 ^@ Similarity ^@ Belongs to the UPP synthase family. http://togogenome.org/gene/13146:LOC101879629 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intermediate filament family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101869332 ^@ http://purl.uniprot.org/uniprot/A0A8C6N789 ^@ Similarity ^@ Belongs to the ubiquitin-activating E1 family. http://togogenome.org/gene/13146:LOC101881049 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUB3 ^@ Similarity ^@ In the C-terminal section; belongs to the OMP decarboxylase family.|||In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/13146:LOC101869013 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874404 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/13146:LOC101869943 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101877286 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Cytoplasm http://togogenome.org/gene/13146:LOC101876702 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBD1 ^@ Similarity ^@ Belongs to the CAND family. http://togogenome.org/gene/13146:LOC101868476 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urotensin-2 family.|||Secreted http://togogenome.org/gene/13146:LOC101871171 ^@ http://purl.uniprot.org/uniprot/A0A8C6K552 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101875726 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0F2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101880860 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDJ1 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/13146:LOC101875164 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101876049 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Q4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tenascin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101868380 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU11 ^@ Function|||Similarity ^@ Belongs to the type I cytokine receptor family. Type 1 subfamily.|||The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling. http://togogenome.org/gene/13146:LOC101872691 ^@ http://purl.uniprot.org/uniprot/A0A8C6J794 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/13146:LOC101870312 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2Y2 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101879293 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGB5 ^@ Function ^@ Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain. http://togogenome.org/gene/13146:LOC101872340 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB78 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/13146:LOC101879088 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVD8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/13146:LOC101871673 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/13146:LOC101873159 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXV0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101871229 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAR6 family.|||Cytoplasm|||tight junction http://togogenome.org/gene/13146:LOC101871524 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC93|||http://purl.uniprot.org/uniprot/A0A8C6JGG6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101879692 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFG0 ^@ Activity Regulation|||Similarity|||Subunit ^@ Belongs to the protein kinase superfamily. Alpha-type protein kinase family.|||Monomer or homodimer.|||Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent. http://togogenome.org/gene/13146:LOC101874646 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101871379 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SMU1 family.|||Nucleus speckle http://togogenome.org/gene/13146:LOC101879548 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAE8 ^@ Subcellular Location Annotation ^@ Apical cell membrane|||Cell membrane|||Lipid droplet http://togogenome.org/gene/13146:LOC101875287 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDU8 ^@ Similarity ^@ Belongs to the FBXO45/Fsn family. http://togogenome.org/gene/13146:LOC101879236 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101880274 ^@ http://purl.uniprot.org/uniprot/A0A8C6J534 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 31 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101872472 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGY7 ^@ Similarity ^@ Belongs to the peptidase C48 family. http://togogenome.org/gene/13146:LOC101881859 ^@ http://purl.uniprot.org/uniprot/A0A8C6N899 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Nucleus http://togogenome.org/gene/13146:LOC101874223 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7H1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101869141 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWY9 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/13146:LOC101869451 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZA2 ^@ Similarity ^@ Belongs to the CDV3 family. http://togogenome.org/gene/13146:LOC101870550 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTX0 ^@ Similarity ^@ Belongs to the osteocalcin/matrix Gla protein family. http://togogenome.org/gene/13146:LOC101880488 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM TRSPAP family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101881374 ^@ http://purl.uniprot.org/uniprot/A0A8C6J268 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101877169 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ67 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/13146:LOC101878584 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Q4 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/13146:LOC101868253 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLR1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869321 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the urea transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871230 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.|||Monomer.|||Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.|||cytosol http://togogenome.org/gene/13146:LOC101881826 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW35 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/13146:LOC101877493 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7K2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCZ1 family.|||Lysosome membrane http://togogenome.org/gene/13146:LOC101880358 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LDAF1 family.|||Endoplasmic reticulum membrane|||Lipid droplet|||Membrane http://togogenome.org/gene/13146:LOC101880154 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Y2 ^@ Similarity ^@ Belongs to the PHF5 family. http://togogenome.org/gene/13146:LOC101868691 ^@ http://purl.uniprot.org/uniprot/A0A8C6K9W8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101873329 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3L6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasmic vesicle|||Endosome|||Golgi apparatus|||May act by regulating membrane trafficking and cellular morphogenesis.|||Recycling endosome|||Vesicle|||autophagosome|||perinuclear region|||trans-Golgi network http://togogenome.org/gene/13146:LOC101867688 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3R5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. http://togogenome.org/gene/13146:LOC101874872 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXH1 ^@ Similarity ^@ Belongs to the DNA/RNA non-specific endonuclease family. http://togogenome.org/gene/13146:LOC101873257 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXZ5 ^@ Similarity ^@ Belongs to the small GTPase superfamily. RGK family. http://togogenome.org/gene/13146:LOC101879354 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/13146:LOC101873385 ^@ http://purl.uniprot.org/uniprot/A0A8C6N609 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calcium channel flower family.|||Membrane http://togogenome.org/gene/13146:LOC101868219 ^@ http://purl.uniprot.org/uniprot/A0A8C6K075 ^@ Caution|||Similarity ^@ Belongs to the lipoxygenase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101868005 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUU4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101868001 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVI9 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874712 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC97 ^@ Subcellular Location Annotation ^@ Cell membrane|||invadopodium membrane|||lamellipodium membrane http://togogenome.org/gene/13146:LOC101874303 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZK9 ^@ Function|||Similarity ^@ Belongs to the cytidylyltransferase family.|||Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis. http://togogenome.org/gene/13146:LOC101874655 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVH4 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101879550 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW09 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101875235 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWZ6 ^@ Similarity ^@ Belongs to the beta/gamma-crystallin family. http://togogenome.org/gene/13146:LOC101876616 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7N5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SYS1 family.|||Golgi apparatus membrane|||Interacts with ARFRP1.|||Involved in protein trafficking. May serve as a receptor for ARFRP1.|||Membrane http://togogenome.org/gene/13146:LOC101878000 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN89 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101878893 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBA6 ^@ Similarity ^@ Belongs to the FAM214 family. http://togogenome.org/gene/13146:LOC101880903 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGK8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869434 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cleavage furrow|||Midbody|||cilium membrane|||spindle http://togogenome.org/gene/13146:LOC101874262 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0L8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS7 family. http://togogenome.org/gene/13146:LOC101871583 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAF0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC3 family.|||Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.|||Nucleus http://togogenome.org/gene/13146:LOC101875995 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLA5 ^@ Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family. http://togogenome.org/gene/13146:LOC101873801 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase C13 family.|||Forms a complex with PIGT, PIGS, PIGU and GAA1.|||Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. http://togogenome.org/gene/13146:LOC101878411 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6W5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the poly(A) polymerase family.|||Binds 2 magnesium ions. Also active with manganese.|||Nucleus|||Polymerase that creates the 3'-poly(A) tail of mRNA's. http://togogenome.org/gene/13146:LOC101868940 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0A1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CLUAP1 family.|||cilium http://togogenome.org/gene/13146:LOC101880391 ^@ http://purl.uniprot.org/uniprot/A0A8C6N770 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Nucleus http://togogenome.org/gene/13146:LOC101879992 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAP family.|||Cell membrane http://togogenome.org/gene/13146:LOC101881843 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGC4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus|||Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. http://togogenome.org/gene/13146:LOC101876195 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gastrin/cholecystokinin family.|||Secreted http://togogenome.org/gene/13146:LOC101872944 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG90 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/13146:LOC101879327 ^@ http://purl.uniprot.org/uniprot/A0A8C6K062 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNEP1R1 family.|||Cytoplasm|||Membrane|||Nucleus membrane http://togogenome.org/gene/13146:LOC101872906 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MTUS1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101868053 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-X family.|||Nucleus http://togogenome.org/gene/13146:LOC101878308 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYH2 ^@ Similarity ^@ Belongs to the complex I 30 kDa subunit family. http://togogenome.org/gene/13146:LOC101877071 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dickkopf family.|||Secreted http://togogenome.org/gene/13146:LOC101880243 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW22 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/13146:LOC101880380 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.|||Nucleus|||centrosome http://togogenome.org/gene/13146:LOC101876620 ^@ http://purl.uniprot.org/uniprot/A0A8C6K582 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101880933 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3Y3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha-carbonic anhydrase family.|||Cytoplasm|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/13146:LOC101880705 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS38 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/13146:LOC101871473 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCMBP family.|||Nucleus http://togogenome.org/gene/13146:LOC101869044 ^@ http://purl.uniprot.org/uniprot/A0A8C6J557 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/13146:LOC101871462 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6T0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Integrator subunit 8 family.|||Nucleus http://togogenome.org/gene/13146:LOC101876789 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITR1 ^@ Similarity ^@ Belongs to the synaptotagmin family. http://togogenome.org/gene/13146:LOC101877727 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN82 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/13146:LOC101880744 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCP4 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101869535 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPT9 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101875125 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6I6 ^@ Similarity ^@ Belongs to the Tdpoz family. http://togogenome.org/gene/13146:LOC101878861 ^@ http://purl.uniprot.org/uniprot/A0A8C6J452 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101868641 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGS8 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Heterodimer of a light chain and a heavy chain linked by a disulfide bond.|||Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101870309 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWV8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC73 family.|||Nucleus http://togogenome.org/gene/13146:LOC101869779 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXH7 ^@ Similarity ^@ Belongs to the 3-beta-HSD family. http://togogenome.org/gene/13146:LOC101868843 ^@ http://purl.uniprot.org/uniprot/A0A8C6J422 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shugoshin family.|||centromere http://togogenome.org/gene/13146:LOC101877559 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/13146:LOC101881258 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM242 family.|||Membrane http://togogenome.org/gene/13146:LOC101870386 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFP2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.|||Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. http://togogenome.org/gene/13146:LOC101873900 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874817 ^@ http://purl.uniprot.org/uniprot/A0A8C6JET4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL1 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane|||The C-terminal di-lysine motif may confer endoplasmic reticulum localization. http://togogenome.org/gene/13146:LOC101874969 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6H7 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/13146:LOC101878412 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pecanex family.|||Membrane http://togogenome.org/gene/13146:LOC101876748 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXZ9 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/13146:LOC101877527 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/13146:LOC101869199 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITL1 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/13146:LOC101875777 ^@ http://purl.uniprot.org/uniprot/A0A8C6KAV7 ^@ Similarity ^@ Belongs to the proteasome subunit p55 family. http://togogenome.org/gene/13146:LOC101875500 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872963 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8F4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101868383 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9R8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.|||Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/13146:LOC101873996 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5Y9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK6 subfamily.|||Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.|||Cajal body|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. Interacts with COIL (via C-terminus).|||nucleoplasm http://togogenome.org/gene/13146:LOC101879672 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ99 ^@ Similarity ^@ Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family. http://togogenome.org/gene/13146:LOC101878407 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0389 family.|||Membrane http://togogenome.org/gene/13146:LOC101878148 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBF1 ^@ Similarity ^@ Belongs to the TOM1 family. http://togogenome.org/gene/13146:LOC101878579 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Q7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101868759 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCW5 ^@ Similarity ^@ Belongs to the teashirt C2H2-type zinc-finger protein family. http://togogenome.org/gene/13146:LOC101876800 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR04 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869534 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLE5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101876213 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5H7 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/13146:LOC101880308 ^@ http://purl.uniprot.org/uniprot/A0A8C6K574 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/13146:LOC101881635 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAVIN family.|||caveola http://togogenome.org/gene/13146:LOC101871637 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101879232 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the raftlin family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876413 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV90 ^@ Function|||Similarity ^@ Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.|||Probable lipase. http://togogenome.org/gene/13146:LOC101879422 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7G1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/13146:LOC101880609 ^@ http://purl.uniprot.org/uniprot/A0A8C6JME7 ^@ Similarity ^@ Belongs to the glutaredoxin family. http://togogenome.org/gene/13146:LOC101875426 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISD1 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/13146:LOC101880376 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1U7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/13146:LOC101877876 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cystinosin family.|||Membrane http://togogenome.org/gene/13146:LOC101874638 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873219 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXC3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TFIIE beta subunit family.|||Nucleus|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.|||Tetramer of two alpha and two beta chains. http://togogenome.org/gene/13146:LOC101868136 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTB7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane|||Sulfate transporter. May play a role in endochondral bone formation. http://togogenome.org/gene/13146:LOC101878342 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT04 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. http://togogenome.org/gene/13146:LOC101872566 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101877973 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101878004 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NGF-beta family.|||Secreted|||Seems to promote the survival of visceral and proprioceptive sensory neurons. http://togogenome.org/gene/13146:LOC101873800 ^@ http://purl.uniprot.org/uniprot/A0A8C6J242 ^@ Function|||Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability. http://togogenome.org/gene/13146:LOC101873630 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101880355 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE06 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/13146:LOC101881331 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVH6 ^@ Similarity ^@ Belongs to the cytochrome b5 family. http://togogenome.org/gene/13146:LOC101881874 ^@ http://purl.uniprot.org/uniprot/A0A8C6N841 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synapse|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101874361 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/13146:LOC101877831 ^@ http://purl.uniprot.org/uniprot/A0A8C6INU8 ^@ Similarity ^@ Belongs to the peptidase M76 family. http://togogenome.org/gene/13146:LOC101876050 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE78 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/13146:LOC101875938 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR50 ^@ Similarity ^@ Belongs to the calponin family. http://togogenome.org/gene/13146:LOC101880319 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZB2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS11 family. http://togogenome.org/gene/13146:LOC101877971 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ITPRIP family.|||Cell membrane|||Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.|||Membrane|||Nucleus outer membrane http://togogenome.org/gene/13146:LOC101881592 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NECAP family.|||Involved in endocytosis.|||clathrin-coated vesicle membrane http://togogenome.org/gene/13146:LOC101870987 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/13146:LOC101868164 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC99 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/13146:LOC101878150 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFV9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Common component of the spliceosome and rRNA processing machinery.|||nucleolus http://togogenome.org/gene/13146:LOC101877348 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9V1 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/13146:LOC101876372 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type II (or gamma) interferon family.|||Homodimer.|||Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.|||Secreted http://togogenome.org/gene/13146:LOC101871612 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB44 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878856 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIG1 family.|||Membrane http://togogenome.org/gene/13146:LOC101875854 ^@ http://purl.uniprot.org/uniprot/A0A8C6N755 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872677 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFZ4 ^@ Similarity ^@ Belongs to the RIB43A family. http://togogenome.org/gene/13146:LOC101868629 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVZ0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/13146:LOC101875484 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXF4 ^@ Function|||Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells. http://togogenome.org/gene/13146:LOC101876120 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9D0 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101878892 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTV7 ^@ Subcellular Location Annotation|||Subunit ^@ Membrane|||The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits. http://togogenome.org/gene/13146:LOC101870820 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNP4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878975 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with VGF-derived peptide TLQP-21.|||Membrane|||Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production. http://togogenome.org/gene/13146:LOC101879734 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CWC25 family.|||Nucleus http://togogenome.org/gene/13146:LOC101881158 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARL2BP family.|||Cytoplasm|||Mitochondrion intermembrane space|||Nucleus|||Plays a role as an effector of the ADP-ribosylation factor-like protein 2, ARL2.|||centrosome|||cilium basal body http://togogenome.org/gene/13146:LOC101868588 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPRING family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101880681 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR46 ^@ Similarity ^@ Belongs to the ZC3H12 family. http://togogenome.org/gene/13146:LOC101870712 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101881034 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101881593 ^@ http://purl.uniprot.org/uniprot/A0A8C6J695 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/13146:LOC101881163 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIPK family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101871032 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1T4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family.|||Nucleus http://togogenome.org/gene/13146:LOC101875984 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101875335 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. C/EBP subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101877674 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK91 ^@ Similarity|||Subunit ^@ Belongs to the EMC7 family.|||Component of the ER membrane protein complex (EMC). http://togogenome.org/gene/13146:LOC101874976 ^@ http://purl.uniprot.org/uniprot/A0A8C6J764 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/13146:LOC101871798 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVI6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. http://togogenome.org/gene/13146:LOC101869946 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNR0 ^@ Similarity ^@ Belongs to the nucleoporin NSP1/NUP62 family. http://togogenome.org/gene/13146:LOC101878165 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKU1 ^@ Similarity ^@ Belongs to the AP-2 family. http://togogenome.org/gene/13146:LOC101879817 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS5 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101870347 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDD5 ^@ Caution|||Function ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin. http://togogenome.org/gene/13146:LOC101870093 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101879925 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101873782 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGB family.|||Chromosome http://togogenome.org/gene/13146:LOC101881559 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2E0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101876356 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBE3 ^@ Function|||Similarity ^@ Belongs to the SHOC2 family.|||Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes. http://togogenome.org/gene/13146:LOC101880693 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/13146:LOC101876415 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY29 ^@ Similarity ^@ Belongs to the thymidylate synthase family. http://togogenome.org/gene/13146:LOC101877284 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101877038 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEP0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880030 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SF3B1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101873090 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8W0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycoprotein hormones subunit alpha family.|||Heterodimer of an alpha and a beta chain.|||Secreted http://togogenome.org/gene/13146:LOC101869982 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAR7 ^@ Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/13146:LOC101880233 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0U0 ^@ Subcellular Location Annotation ^@ Membrane|||basement membrane http://togogenome.org/gene/13146:LOC101868372 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW51 ^@ Similarity ^@ Belongs to the RimK family. http://togogenome.org/gene/13146:LOC101872035 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6E3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101868859 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUN2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101870110 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.|||Golgi apparatus http://togogenome.org/gene/13146:LOC101878110 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZH1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tetraspanin (TM4SF) family.|||Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).|||Membrane http://togogenome.org/gene/13146:LOC101873449 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101876169 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868837 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNJ5 ^@ Similarity ^@ Belongs to the UPF0587 family. http://togogenome.org/gene/13146:LOC101881930 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBZ6 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101870264 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 3 family.|||Membrane http://togogenome.org/gene/13146:LOC101880225 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101881146 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL90 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the insulin family.|||Heterodimer of a B chain and an A chain linked by two disulfide bonds.|||Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.|||Secreted http://togogenome.org/gene/13146:LOC101868968 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCS5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101873491 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZX8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus|||Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. http://togogenome.org/gene/13146:LOC101880586 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR64 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX59 subfamily. http://togogenome.org/gene/13146:LOC101870344 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBT6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871283 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNR ribonuclease family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101873716 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3N7 ^@ Similarity|||Subunit ^@ Belongs to the archease family.|||Component of the tRNA-splicing ligase complex. http://togogenome.org/gene/13146:LOC101870166 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ33 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/13146:LOC101871121 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBU1 ^@ Similarity ^@ Belongs to the NAD(P)H dehydrogenase (quinone) family. http://togogenome.org/gene/13146:LOC101879161 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ASF1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101881042 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/13146:LOC101872137 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN47|||http://purl.uniprot.org/uniprot/A0A8C6N6A0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101874980 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIE0 ^@ Similarity|||Subunit ^@ Belongs to the ENDOU family.|||Monomer. http://togogenome.org/gene/13146:LOC101879302 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCQ3 ^@ Similarity ^@ Belongs to the CEF1 family. http://togogenome.org/gene/13146:LOC101877505 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101870985 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3N4 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101871615 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.|||Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN.|||May affect the rate of fibrils formation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101867807 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAN1 family.|||Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.|||Nucleus http://togogenome.org/gene/13146:LOC101871350 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU03 ^@ Similarity ^@ Belongs to the CCDC53 family. http://togogenome.org/gene/13146:LOC101876610 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/13146:LOC101873383 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISL4 ^@ Similarity ^@ Belongs to the adenomatous polyposis coli (APC) family. http://togogenome.org/gene/13146:LOC101881199 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MND1 family.|||Nucleus|||Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. http://togogenome.org/gene/13146:LOC101871259 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM163 family.|||Membrane http://togogenome.org/gene/13146:LOC101870699 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/13146:LOC101878797 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5J5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the C1D family.|||Cytoplasm|||Monomer and homodimer.|||Nucleus|||Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.|||nucleolus http://togogenome.org/gene/13146:LOC101878018 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5D5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101881305 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872048 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-B-like family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101880333 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cornichon family.|||Membrane http://togogenome.org/gene/13146:LOC101874982 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2L5 ^@ Similarity ^@ Belongs to the LDB family. http://togogenome.org/gene/13146:LOC101869182 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWV6 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/13146:LOC101868325 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQU3 ^@ Function|||Similarity ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. http://togogenome.org/gene/13146:LOC101871635 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8R7 ^@ Similarity ^@ Belongs to the actin-binding proteins ADF family. GMF subfamily. http://togogenome.org/gene/13146:LOC101879612 ^@ http://purl.uniprot.org/uniprot/A0A8C6J327 ^@ Similarity ^@ Belongs to the BACURD family. http://togogenome.org/gene/13146:LOC101869172 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DMRT family.|||Nucleus http://togogenome.org/gene/13146:LOC101877786 ^@ http://purl.uniprot.org/uniprot/A0A8C6J227 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.|||Belongs to the glycosyltransferase 22 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101867911 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIG1 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/13146:LOC101875297 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV71 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101869252 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SCC3 family.|||Chromosome|||Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.|||Nucleus|||Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.|||centromere http://togogenome.org/gene/13146:LOC101873333 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Q6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.|||Belongs to the SNF2/RAD54 helicase family.|||Component of the INO80 chromatin-remodeling complex.|||Nucleus|||The DBINO region is involved in binding to DNA. http://togogenome.org/gene/13146:LOC101877432 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITJ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/13146:LOC101875129 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX47 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101873799 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Secreted http://togogenome.org/gene/13146:LOC101874949 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101868632 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ00 ^@ Similarity ^@ Belongs to the PRPH2/ROM1 family. http://togogenome.org/gene/13146:LOC101874566 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFD6 ^@ Similarity ^@ Belongs to the TTC19 family. http://togogenome.org/gene/13146:LOC101877828 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Lipocalin family.|||Secreted http://togogenome.org/gene/13146:LOC101868730 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNP3 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/13146:LOC101868188 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0X5 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/13146:LOC101870762 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS21 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/13146:LOC101875710 ^@ http://purl.uniprot.org/uniprot/A0A8C6J286 ^@ Similarity ^@ Belongs to the GET4 family. http://togogenome.org/gene/13146:LOC101881362 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0N4 ^@ Subcellular Location Annotation ^@ nuclear pore complex http://togogenome.org/gene/13146:LOC101867805 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYI9|||http://purl.uniprot.org/uniprot/A0A8C6K1K5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/13146:LOC101879509 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHD1 ^@ Similarity ^@ Belongs to the Ntn-hydrolase family. http://togogenome.org/gene/13146:LOC101872647 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE66 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha/beta interferon family.|||Has antiviral activities.|||Secreted http://togogenome.org/gene/13146:LOC101879309 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101870174 ^@ http://purl.uniprot.org/uniprot/A0A8C6J638 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LTN1 family.|||Component of the ribosome quality control complex (RQC).|||E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.|||cytosol http://togogenome.org/gene/13146:LOC101871213 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMQ0 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/13146:AOX1 ^@ http://purl.uniprot.org/uniprot/M1ZMJ9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xanthine dehydrogenase family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Binds 2 [2Fe-2S] clusters.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/13146:LOC101871899 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL41 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/13146:LOC101877911 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW33 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871198 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZQ5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101870673 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKC7 ^@ Similarity ^@ Belongs to the LplA family. http://togogenome.org/gene/13146:LOC101880420 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ27 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/13146:LOC101879770 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMR5 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the aldo/keto reductase family.|||Cell membrane|||Membrane|||cytosol http://togogenome.org/gene/13146:LOC101871099 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISW2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101873562 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101873798 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ29 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aldolase class II family. Adducin subfamily.|||Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.|||Cytoplasm http://togogenome.org/gene/13146:LOC101877272 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9A7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Cell membrane|||Cytoplasm|||Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/13146:LOC101877660 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4Q5 ^@ Subcellular Location Annotation ^@ Nucleus|||cytosol http://togogenome.org/gene/13146:LOC101869209 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZX7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts specifically as a negative regulator of skeletal muscle growth.|||Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Secreted http://togogenome.org/gene/13146:LOC101873339 ^@ http://purl.uniprot.org/uniprot/A0A8C6N925 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Membrane http://togogenome.org/gene/13146:LOC101879828 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1H6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane|||Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.|||Vacuole membrane|||clathrin-coated vesicle membrane|||synaptic vesicle membrane http://togogenome.org/gene/13146:LOC101876544 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRI3 ^@ Domain|||Subcellular Location Annotation ^@ The N-terminal C2 domain associates with lipid membranes upon calcium binding.|||cytosol http://togogenome.org/gene/13146:LOC101880542 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||Cleavage furrow|||Midbody|||cilium membrane|||spindle http://togogenome.org/gene/13146:LOC101874151 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHL4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPE family.|||Cytoplasm|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/13146:LOC101874516 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LRRC8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101870964 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family.|||Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.|||Homodimer.|||Peroxisome http://togogenome.org/gene/13146:LOC101879419 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2B6 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond.|||acrosome|||flagellum http://togogenome.org/gene/13146:LOC101869217 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLE3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101867645 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0669 family.|||Secreted http://togogenome.org/gene/13146:LOC101877880 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879668 ^@ http://purl.uniprot.org/uniprot/A0A8C6J126 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101869926 ^@ http://purl.uniprot.org/uniprot/A0A8C6J596 ^@ Similarity ^@ Belongs to the PP2C family. http://togogenome.org/gene/13146:LOC101874510 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFG7 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101873850 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8H1 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/13146:LOC101872126 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFN1 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/13146:LOC101871613 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUX5 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/13146:LOC101878689 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6J2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL53 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101874069 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZR0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.|||Mitochondrion http://togogenome.org/gene/13146:LOC101872478 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MTFR1 family.|||Mitochondrion|||Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission. http://togogenome.org/gene/13146:LOC101877458 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB79 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/13146:LOC101877633 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3V5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101878639 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQW5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/13146:LOC101878926 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SH3PXD2 family.|||Cytoplasm|||podosome http://togogenome.org/gene/13146:LOC101873193 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY28 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transcriptional coactivator PC4 family.|||General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).|||Nucleus http://togogenome.org/gene/13146:LOC101872131 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Nucleus http://togogenome.org/gene/13146:LOC101876868 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NIPA family.|||Membrane http://togogenome.org/gene/13146:LOC101878619 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the caveolin family.|||Cell membrane|||Golgi apparatus membrane|||May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.|||Membrane|||Membrane raft|||caveola http://togogenome.org/gene/13146:LOC101881413 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8A9 ^@ Similarity ^@ Belongs to the SS18 family. http://togogenome.org/gene/13146:LOC101881038 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQA2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101872624 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEY6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101870773 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101878428 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9B6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane|||Probable fucosyltransferase. http://togogenome.org/gene/13146:LOC101877409 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/13146:LOC101872965 ^@ http://purl.uniprot.org/uniprot/A0A8C6J438 ^@ Subcellular Location Annotation ^@ Golgi apparatus|||perinuclear region http://togogenome.org/gene/13146:LOC101877548 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9Y4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/13146:LOC101880982 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF4 family.|||Nucleus http://togogenome.org/gene/13146:LOC101881345 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA43 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 59 family. http://togogenome.org/gene/13146:LOC101872559 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLA9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CCDC25 family.|||Cell membrane|||Endomembrane system|||Interacts (via cytoplasmic region) with ILK. http://togogenome.org/gene/13146:LOC101870551 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Y1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101880578 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJD2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat WDR12/YTM1 family.|||Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.|||Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.|||nucleolus|||nucleoplasm http://togogenome.org/gene/13146:LOC101877040 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRW8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/13146:LOC101879648 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9T2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic RPB8 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. http://togogenome.org/gene/13146:LOC101869185 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the grh/CP2 family. CP2 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101880162 ^@ http://purl.uniprot.org/uniprot/A0A8C6ING7 ^@ Similarity ^@ Belongs to the Gfo/Idh/MocA family. http://togogenome.org/gene/13146:LOC101869782 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6P1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTR/RAG GTP-binding protein family.|||Cytoplasm|||Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.|||Lysosome http://togogenome.org/gene/13146:LOC101880743 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8A8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101870889 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA42 ^@ Function|||Similarity ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. http://togogenome.org/gene/13146:LOC101880588 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2I2 ^@ Similarity ^@ Belongs to the CGI121/TPRKB family. http://togogenome.org/gene/13146:LOC101877240 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/13146:LOC101875667 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101872986 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.|||Membrane http://togogenome.org/gene/13146:LOC101872799 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY72 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/13146:LOC101873180 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101867925 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4X7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NOP14 family.|||Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.|||nucleolus http://togogenome.org/gene/13146:LOC101875842 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAI9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation. http://togogenome.org/gene/13146:LOC101873379 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS8 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101874365 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUS7 ^@ Similarity ^@ Belongs to the SS18 family. http://togogenome.org/gene/13146:LOC101869690 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBY9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101871829 ^@ http://purl.uniprot.org/uniprot/A0A8C6K881 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Membrane http://togogenome.org/gene/13146:LOC101875718 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXZ3 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/13146:LOC101870499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU76 ^@ Function|||Similarity ^@ Belongs to the ARPC5 family.|||Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. http://togogenome.org/gene/13146:LOC101871131 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2K1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/13146:LOC101878217 ^@ http://purl.uniprot.org/uniprot/A0A8C6JER7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PNRC family. PNRC2 subfamily.|||Nucleus|||P-body http://togogenome.org/gene/13146:LOC101869925 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRB3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 79 family. http://togogenome.org/gene/13146:LOC101878527 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.|||Belongs to the peptidase S16 family.|||Peroxisome matrix http://togogenome.org/gene/13146:LOC101879535 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ92 ^@ Similarity ^@ Belongs to the G-alpha family. G(s) subfamily. http://togogenome.org/gene/13146:LOC101875851 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9P2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cathelicidin family.|||Secreted http://togogenome.org/gene/13146:LOC101881414 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCV7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. http://togogenome.org/gene/13146:LOC101871694 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQI7 ^@ Function|||Similarity ^@ Belongs to the PET191 family.|||Involved in an early step of the mitochondrial complex IV assembly process. http://togogenome.org/gene/13146:LOC101871965 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0L5 ^@ Function|||Similarity ^@ Belongs to the SAP18 family.|||Involved in the tethering of the SIN3 complex to core histone proteins. http://togogenome.org/gene/13146:LOC101873522 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP17 family.|||nucleolus http://togogenome.org/gene/13146:LOC101874336 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM263 family.|||Membrane http://togogenome.org/gene/13146:LOC101870451 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CMC family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101880748 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBJ3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101875732 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1L0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101873727 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAL2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101877241 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKG0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879654 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQG6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the exportin family.|||Cytoplasm|||Nucleus|||tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. http://togogenome.org/gene/13146:LOC101879425 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6L2 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/13146:LOC101875735 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEU2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101880492 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. PAR subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101881571 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9U0 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/13146:LOC101878310 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ10 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C78 family. ZUFSP subfamily.|||Interacts with RPA1 and RPA2. http://togogenome.org/gene/13146:LOC101879778 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UDP-glycosyltransferase family.|||Membrane http://togogenome.org/gene/13146:LOC101873892 ^@ http://purl.uniprot.org/uniprot/A0A8C6K356 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101880213 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BORCS7 family.|||Membrane http://togogenome.org/gene/13146:LOC101872416 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ97 ^@ Similarity ^@ Belongs to the peptidase M50A family. http://togogenome.org/gene/13146:LOC101872412 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/13146:LOC101877097 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVN5 ^@ Similarity ^@ Belongs to the multicopper oxidase family. http://togogenome.org/gene/13146:LOC101875877 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG69 ^@ Similarity ^@ Belongs to the rad9 family. http://togogenome.org/gene/13146:LOC101871887 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR60 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.|||cytosol http://togogenome.org/gene/13146:LOC101868829 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFF5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/13146:LOC101880871 ^@ http://purl.uniprot.org/uniprot/A0A8C6N728 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ARV1 family.|||Endoplasmic reticulum membrane|||Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.|||Membrane http://togogenome.org/gene/13146:LOC101874465 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 28 family.|||Nucleus http://togogenome.org/gene/13146:LOC101869300 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWU2 ^@ Similarity ^@ Belongs to the arrestin family. http://togogenome.org/gene/13146:LOC101868045 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX89 ^@ Similarity ^@ Belongs to the profilin family. http://togogenome.org/gene/13146:LOC101876387 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW01 ^@ Similarity ^@ Belongs to the CAND family. http://togogenome.org/gene/13146:LOC101879196 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU12 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/13146:LOC101881867 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS43 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/13146:LOC101877107 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8C9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101871858 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFQ2 ^@ Similarity ^@ Belongs to the splicing factor SR family. http://togogenome.org/gene/13146:LOC101874527 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCF4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.|||Cytoplasm|||Nucleus|||Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs. http://togogenome.org/gene/13146:LOC101874274 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101870893 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101881862 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0Y5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/13146:LOC101881608 ^@ http://purl.uniprot.org/uniprot/A0A8C6N703 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878618 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6J6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EXO84 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|||growth cone|||perinuclear region http://togogenome.org/gene/13146:LOC101881599 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWS9 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/13146:LOC101876837 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT44 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/13146:LOC101870601 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMIM19 family.|||Membrane http://togogenome.org/gene/13146:LOC101880338 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I LYR family. SDHAF3 subfamily.|||Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.|||Mitochondrion matrix|||Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1. http://togogenome.org/gene/13146:LOC101872546 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEN0 ^@ Similarity ^@ Belongs to the NSRP1 family. http://togogenome.org/gene/13146:LOC101877916 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPC8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101867716 ^@ http://purl.uniprot.org/uniprot/A0A8C6IL40 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily. http://togogenome.org/gene/13146:LOC101880907 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0D5|||http://purl.uniprot.org/uniprot/A0A8C6N8Z6 ^@ Similarity ^@ Belongs to the LEM family. http://togogenome.org/gene/13146:LOC101870169 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR93 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/13146:LOC101876671 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Z1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101867653 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ70 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101880589 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNI0 ^@ Similarity ^@ Belongs to the WD repeat PRL1/PRL2 family. http://togogenome.org/gene/13146:LOC101876481 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876891 ^@ http://purl.uniprot.org/uniprot/A0A8C6J159 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/13146:LOC101879864 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the actin family. ARP8 subfamily.|||Chromosome|||Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.|||Nucleus|||Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.|||Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. http://togogenome.org/gene/13146:LOC101881746 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA5 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101875887 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6A7 ^@ Similarity ^@ Belongs to the prickle / espinas / testin family. http://togogenome.org/gene/13146:LOC101867686 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101868970 ^@ http://purl.uniprot.org/uniprot/A0A8C6J740 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome complex.|||Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101869945 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1W5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/13146:LOC101879468 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8D9 ^@ Similarity ^@ Belongs to the BRAG family. http://togogenome.org/gene/13146:LOC101872614 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.|||Secreted http://togogenome.org/gene/13146:LOC101876288 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2S7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.|||Belongs to the TRM44 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868364 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 7 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101875155 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Early endosome membrane|||Endosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101869315 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG62 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101879700 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSJ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/13146:LOC101868032 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDD0 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101876694 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6Z0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101875412 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the selenium-binding protein family.|||Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.|||Membrane|||Nucleus|||cytosol http://togogenome.org/gene/13146:LOC101872766 ^@ http://purl.uniprot.org/uniprot/A0A8C6K415 ^@ Similarity ^@ Belongs to the protease inhibitor I47 (latexin) family. http://togogenome.org/gene/13146:LOC101880550 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7U1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/13146:LOC101868191 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAQ6 ^@ Similarity ^@ Belongs to the opioid growth factor receptor family. http://togogenome.org/gene/13146:LOC101868887 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG32 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNF168 family.|||E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Nucleus|||The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs). http://togogenome.org/gene/13146:LOC101878472 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/13146:LOC101880366 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCT6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.|||Membrane|||Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion. http://togogenome.org/gene/13146:LOC101878014 ^@ http://purl.uniprot.org/uniprot/A0A8C6J444 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the stathmin family.|||Cytoplasm|||Membrane|||lamellipodium http://togogenome.org/gene/13146:LOC101869171 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101873500 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX47 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Putative Notch ligand involved in the mediation of Notch signaling. http://togogenome.org/gene/13146:LOC101873804 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLPH3/VPS74 family.|||Golgi stack membrane|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101881386 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA91 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/13146:LOC101877582 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC07 ^@ Subcellular Location Annotation ^@ interphotoreceptor matrix http://togogenome.org/gene/13146:LOC101874188 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH60 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101874639 ^@ http://purl.uniprot.org/uniprot/A0A8C6K795 ^@ Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the CD36 family.|||Cell membrane|||Golgi apparatus|||Membrane|||Membrane raft http://togogenome.org/gene/13146:LOC101868700 ^@ http://purl.uniprot.org/uniprot/A0A8C6K409 ^@ Caution|||Similarity ^@ Belongs to the plexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101873091 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM18 family.|||Membrane|||Nucleus membrane http://togogenome.org/gene/13146:LOC101874082 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.|||Endoplasmic reticulum membrane|||Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.|||Membrane http://togogenome.org/gene/13146:LOC101879257 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND99 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase A22A family.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Homodimer.|||Membrane|||Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.|||The PAL motif is required for normal active site conformation. http://togogenome.org/gene/13146:LOC101873883 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQR1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. DCP2 subfamily. http://togogenome.org/gene/13146:LOC101874419 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3G9 ^@ Similarity ^@ Belongs to the IF-3 family. http://togogenome.org/gene/13146:LOC101869450 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2H3 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/13146:LOC101877685 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXB2 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin E subfamily. http://togogenome.org/gene/13146:LOC101872964 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDQ3 ^@ Similarity ^@ Belongs to the SMARCD family. http://togogenome.org/gene/13146:LOC101874260 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/13146:LOC101870692 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIE9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101870035 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8S7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Endoplasmic reticulum membrane|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101880582 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YIP1 family.|||Membrane http://togogenome.org/gene/13146:LOC101869663 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQE7 ^@ Function|||Similarity ^@ Belongs to the NFYB/HAP3 subunit family.|||Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors. http://togogenome.org/gene/13146:LOC101873309 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND38 ^@ Similarity ^@ Belongs to the DDIT4 family. http://togogenome.org/gene/13146:LOC101873680 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSV8 ^@ Similarity ^@ Belongs to the GST superfamily. Theta family. http://togogenome.org/gene/13146:LOC101876419 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101872739 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101876164 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat fritz family.|||Cell membrane|||Membrane|||cilium axoneme http://togogenome.org/gene/13146:LOC101877162 ^@ http://purl.uniprot.org/uniprot/A0A8C6K212 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101874531 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU06 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101874597 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM59 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101879146 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 4HPPD family.|||Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.|||Endoplasmic reticulum membrane|||Golgi apparatus membrane http://togogenome.org/gene/13146:LOC101870012 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8L3 ^@ Subunit ^@ Monomer and homodimer; homodimerization is induced by binding of the substrate. http://togogenome.org/gene/13146:LOC101875879 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4X9 ^@ Caution|||Similarity ^@ Belongs to the peptidase M43B family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101880861 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVH3 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Endosome membrane|||Nucleus|||phagosome|||ruffle http://togogenome.org/gene/13146:LOC101872793 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chondroitin N-acetylgalactosaminyltransferase family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/13146:LOC101868832 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQX4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.|||In the N-terminal section; belongs to the GART family. http://togogenome.org/gene/13146:LOC101867890 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKH2 ^@ Domain|||Function|||PTM|||Subcellular Location Annotation ^@ E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.|||The WWE domain mediates non-covalent poly(ADP-ribose)-binding.|||Ubiquitinated; autoubiquitinated.|||cytosol http://togogenome.org/gene/13146:LOC101873168 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101880437 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB11 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101869775 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDH4 ^@ Similarity ^@ Belongs to the neuritin family. http://togogenome.org/gene/13146:LOC101869807 ^@ http://purl.uniprot.org/uniprot/A0A8C6K808 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/13146:LOC101870544 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CENP-L/IML3 family.|||Nucleus http://togogenome.org/gene/13146:LOC101877789 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/13146:LOC101880914 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.|||Membrane http://togogenome.org/gene/13146:LOC101873185 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101881427 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4V5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/13146:LOC101871535 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP family.|||Membrane|||Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. http://togogenome.org/gene/13146:LOC101879932 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZS6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871626 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYX2 ^@ Similarity|||Subcellular Location Annotation ^@ A band|||Belongs to the KLHL40 family.|||I band http://togogenome.org/gene/13146:LOC101877062 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868760 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSZ0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. http://togogenome.org/gene/13146:LOC101869544 ^@ http://purl.uniprot.org/uniprot/A0A8C6IKH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP72 family.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).|||Cytoplasm http://togogenome.org/gene/13146:LOC101867796 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYU0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101881580 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7C0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LAMP family.|||Endosome membrane http://togogenome.org/gene/13146:LOC101880478 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRP8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871443 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAK0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101869360 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN53 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101873463 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUF6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).|||Nucleus http://togogenome.org/gene/13146:LOC101875104 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.|||Membrane http://togogenome.org/gene/13146:LOC101873464 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0S7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||microvillus http://togogenome.org/gene/13146:LOC101881433 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWF3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS15 family. http://togogenome.org/gene/13146:LOC101880096 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the vasculin family.|||Nucleus http://togogenome.org/gene/13146:LOC101879768 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZJ5 ^@ Caution|||Similarity ^@ Belongs to the CRELD family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101878341 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPH9 ^@ Similarity ^@ Belongs to the cyclin family. Cyclin AB subfamily. http://togogenome.org/gene/13146:LOC101868820 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M28 family. M28B subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101878482 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0M7 ^@ Similarity ^@ Belongs to the ZNF277 family. http://togogenome.org/gene/13146:LOC101868054 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPV8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/13146:LOC101873033 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9I5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868106 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1C3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101871625 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SEC5 family.|||Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.|||Component of the exocyst complex. http://togogenome.org/gene/13146:LOC101880532 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN4 family.|||Nucleus|||Vesicle|||synaptic vesicle http://togogenome.org/gene/13146:LOC101868847 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMJ2 ^@ Function|||Similarity ^@ Belongs to the SAA family.|||Major acute phase reactant. Apolipoprotein of the HDL complex. http://togogenome.org/gene/13146:LOC101873173 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3E5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HAD-like hydrolase superfamily. EYA family.|||Binds 1 Mg(2+) ion per subunit.|||Nucleus http://togogenome.org/gene/13146:LOC101880063 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9R1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101876178 ^@ http://purl.uniprot.org/uniprot/A0A8C6J228 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/13146:LOC101868881 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||tight junction http://togogenome.org/gene/13146:LOC101878787 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endosulfine family.|||Cytoplasm|||Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. http://togogenome.org/gene/13146:LOC101874173 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101878009 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 17 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101877395 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9A1|||http://purl.uniprot.org/uniprot/A0A8C6NB50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMR1 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101872263 ^@ http://purl.uniprot.org/uniprot/A0A8C6N745 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL23 family. http://togogenome.org/gene/13146:LOC101879144 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3S4 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101875459 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILP3 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/13146:LOC101869545 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/13146:LOC101870839 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/13146:LOC101868678 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1U4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880615 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVM9 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.|||Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. http://togogenome.org/gene/13146:LOC101871788 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBP3 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL4 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/13146:LOC101881654 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101876686 ^@ http://purl.uniprot.org/uniprot/A0A8C6J016 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101868598 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYH5 ^@ Similarity ^@ Belongs to the DPH4 family. http://togogenome.org/gene/13146:LOC101881092 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJF2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 13 family.|||Golgi apparatus membrane|||Membrane|||Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.|||The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.|||The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein. http://togogenome.org/gene/13146:LOC101875555 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868549 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIPK family.|||Secreted http://togogenome.org/gene/13146:LOC101874762 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the carnitine/choline acetyltransferase family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101869187 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIN4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/13146:LOC101872519 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family. A subfamily.|||Lipid droplet|||Nucleus|||cell cortex http://togogenome.org/gene/13146:LOC101874417 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101875827 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWT4 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family.|||Belongs to the small GTPase superfamily. SAR1 family. http://togogenome.org/gene/13146:LOC101880292 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IST1 family.|||Cytoplasmic vesicle|||Nucleus envelope http://togogenome.org/gene/13146:LOC101869613 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZX9 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily. http://togogenome.org/gene/13146:LOC101870004 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2N7 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal PrmC-related family. http://togogenome.org/gene/13146:LOC101875673 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4N1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/13146:LOC101875831 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLY7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101873393 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1I2 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/13146:LOC101868545 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBL9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/13146:LOC101875990 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM91 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/13146:LOC101874811 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRJ5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the TET family.|||Binds 1 Fe(2+) ion per subunit.|||Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.|||The zinc ions have a structural role. http://togogenome.org/gene/13146:LOC101879918 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.|||Cell membrane|||Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.|||Membrane http://togogenome.org/gene/13146:LOC101869433 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mo25 family.|||Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.|||Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity. http://togogenome.org/gene/13146:LOC101875000 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC37 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875862 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1V2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101881601 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879484 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. ATF subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101879674 ^@ http://purl.uniprot.org/uniprot/A0A8C6J716 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL15 family. http://togogenome.org/gene/13146:LOC101877229 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLV4 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/13146:LOC101879052 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF12 family.|||Nucleus http://togogenome.org/gene/13146:LOC101876767 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BOD1 family.|||centrosome|||kinetochore http://togogenome.org/gene/13146:LOC101867712 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BROX family.|||Membrane http://togogenome.org/gene/13146:LOC101868561 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNP6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/13146:LOC101874079 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6G9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB1 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101877825 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-17 family.|||Secreted http://togogenome.org/gene/13146:LOC101872205 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101872569 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZIP transporter (TC 2.A.5) family.|||May act as a zinc-influx transporter.|||Membrane http://togogenome.org/gene/13146:LOC101879617 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAV6 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101878571 ^@ http://purl.uniprot.org/uniprot/A0A8C6K7F8 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/13146:LOC101879818 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQU8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101868935 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDG1 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101873947 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHB6 ^@ Similarity ^@ Belongs to the TTC27 family. http://togogenome.org/gene/13146:LOC101869053 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWM9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879092 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRS4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101868883 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWL6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/13146:LOC101871061 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8T1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877384 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/13146:LOC101881828 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6W8 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/13146:LOC101877731 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEY5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Cytoplasmic vesicle membrane|||Endoplasmic reticulum lumen|||Homohexamer. Interacts with TOR1B; the interaction may be specific of neural tissues. Interacts (ATP-bound) with TOR1AIP1 and TOR1AIP2; the interactions induce ATPase activity. Interacts with KLHL14; preferentially when ATP-free. Interacts with KLC1 (via TPR repeats); the interaction associates TOR1A with the kinesin oligomeric complex. Interacts with COPS4; the interaction associates TOR1A with the CSN complex. Interacts with SNAPIN; the interaction is direct and associates SNAPIN with the CSN complex. Interacts with STON2. Interacts (ATP-bound) with SYNE3 (via KASH domain); the interaction is required for SYNE3 nuclear envelope localization. Interacts with VIM; the interaction associates TOR1A with the cytoskeleton. Interacts with PLEC. Interacts (ATP-bound) with SLC6A3; regulates SLC6A3 transport to the plasma membrane.|||Membrane|||growth cone http://togogenome.org/gene/13146:LOC101876221 ^@ http://purl.uniprot.org/uniprot/A0A8C6KAW7 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/13146:LOC101879622 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GOLM family.|||Membrane http://togogenome.org/gene/13146:LOC101877961 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type I cytokine receptor family. Type 2 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101879569 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRX1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the sclerostin family.|||Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. http://togogenome.org/gene/13146:LOC101877734 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPC5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for the neuromedin-U and neuromedin-S neuropeptides. http://togogenome.org/gene/13146:LOC101879172 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101872530 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY90 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster.|||Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. http://togogenome.org/gene/13146:LOC101880940 ^@ http://purl.uniprot.org/uniprot/A0A8C6J945 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.|||Membrane|||desmosome http://togogenome.org/gene/13146:LOC101872960 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG25 ^@ Function|||Similarity ^@ Belongs to the E(R) family.|||May have a role in the cell cycle. http://togogenome.org/gene/13146:LOC101876226 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1V0 ^@ Similarity ^@ Belongs to the ADP-ribosyl cyclase family. http://togogenome.org/gene/13146:LOC101877332 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclin family. Cyclin D subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101879991 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXW3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP300 family.|||Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.|||Cytoplasm http://togogenome.org/gene/13146:LOC101880698 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101869553 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS39 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with FEM1A.|||Membrane|||Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. http://togogenome.org/gene/13146:LOC101878786 ^@ http://purl.uniprot.org/uniprot/A0A8C6JST6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRK1 family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101875121 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPG6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101875311 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6V0 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/13146:LOC101876472 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKA6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101872709 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RuvB family.|||Dynein axonemal particle|||Nucleus|||Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. http://togogenome.org/gene/13146:LOC101876045 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX17 family.|||Mitochondrion intermembrane space http://togogenome.org/gene/13146:LOC101880754 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS69|||http://purl.uniprot.org/uniprot/A0A8C6IU57 ^@ Domain|||Similarity ^@ Belongs to the CAMSAP1 family.|||The CKK domain binds microtubules. http://togogenome.org/gene/13146:LOC101879590 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRH5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Beta-type (group I) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101881405 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101875082 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Q3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Nucleus|||Secreted http://togogenome.org/gene/13146:LOC101869771 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101874538 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3F3 ^@ Function|||Similarity ^@ Belongs to the calbindin family.|||Calretinin is a calcium-binding protein which is abundant in auditory neurons. http://togogenome.org/gene/13146:LOC101880381 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP32 ^@ Similarity ^@ Belongs to the SPT2 family. http://togogenome.org/gene/13146:LOC101878022 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101878904 ^@ http://purl.uniprot.org/uniprot/A0A8C6INY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/13146:LOC101881411 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGV9 ^@ Similarity ^@ Belongs to the alpha-actinin family. http://togogenome.org/gene/13146:LOC101871119 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8D8 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/13146:LOC101878469 ^@ http://purl.uniprot.org/uniprot/A0A8C6INX6 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||RNA-binding protein that regulates alternative splicing events. http://togogenome.org/gene/13146:LOC101877301 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW47 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TIM21 family.|||Component of the TIM23 complex.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101868097 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alkB family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101870505 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2E0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C19 family. USP16 subfamily.|||Homotetramer.|||Nucleus|||Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.|||The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin. http://togogenome.org/gene/13146:LOC101875141 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGR2 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/13146:LOC101872912 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit L family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.|||Cytoplasm http://togogenome.org/gene/13146:LOC101879025 ^@ http://purl.uniprot.org/uniprot/A0A8C6N896 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG4/ERG24 family.|||Membrane http://togogenome.org/gene/13146:LOC101881137 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6H8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/13146:LOC101871825 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9T7 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101871687 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITV2 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/13146:LOC101879251 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWC6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pannexin family.|||Cell membrane|||Membrane|||S-nitrosylation inhibits channel currents and ATP release.|||Structural component of the gap junctions and the hemichannels.|||gap junction http://togogenome.org/gene/13146:LOC101879472 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRL3 ^@ Similarity ^@ Belongs to the TMCO4 family. http://togogenome.org/gene/13146:LOC101870749 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2T6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-gamma family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/13146:LOC101872804 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uL18 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101881834 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.|||Cell membrane|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101876454 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRR2 ^@ Similarity ^@ Belongs to the SAP30 family. http://togogenome.org/gene/13146:LOC101880660 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKI3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/13146:LOC101876043 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin beta chain family.|||Membrane http://togogenome.org/gene/13146:LOC101873944 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1I8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/13146:LOC101873264 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Polycomblike family.|||Nucleus http://togogenome.org/gene/13146:LOC101881100 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Q1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Nucleus|||Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins. http://togogenome.org/gene/13146:LOC101880269 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYU0 ^@ Similarity ^@ Belongs to the calcitonin family. http://togogenome.org/gene/13146:LOC117435841 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101869546 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ69 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871004 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP11 ^@ Subcellular Location Annotation ^@ Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101876095 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Q2 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/13146:LOC101873459 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101871999 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LRRC8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876491 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA38 ^@ Function|||Similarity ^@ Belongs to the AAR2 family.|||Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing. http://togogenome.org/gene/13146:LOC101876401 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0J3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.|||Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.|||Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.|||Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.|||Cytoplasm|||Interacts with KATNB1 and KATNBL1.|||Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.|||centrosome|||cytoskeleton|||spindle|||spindle pole http://togogenome.org/gene/13146:LOC101876681 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXK8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glypican family.|||Cell membrane|||Cell surface proteoglycan that bears heparan sulfate.|||extracellular space http://togogenome.org/gene/13146:LOC101871461 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRS7 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/13146:LOC101877751 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA2/NAM7 helicase family.|||Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.|||Mitochondrion|||Nucleus http://togogenome.org/gene/13146:LOC101871855 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUY1 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101874348 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Q7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.|||Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. http://togogenome.org/gene/13146:LOC101871519 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISZ3 ^@ Similarity ^@ Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. http://togogenome.org/gene/13146:LOC101875712 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVT4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COPG family.|||COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/13146:LOC101875986 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCH3 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/13146:LOC101873566 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6B7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872936 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6U6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870319 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPC8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/13146:LOC101871387 ^@ http://purl.uniprot.org/uniprot/A0A8C6K8W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 61 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101869469 ^@ http://purl.uniprot.org/uniprot/O57605 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Tissue Specificity ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Cone photoreceptor cells.|||Membrane|||Phosphorylated on some or all of the serine and threonine residues present in the C-terminal region.|||Visual pigments are the light-absorbing molecules that mediate vision. They consist of an apoprotein, opsin, covalently linked to cis-retinal. http://togogenome.org/gene/13146:LOC101876927 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Y0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.|||Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor.|||Monomer. http://togogenome.org/gene/13146:LOC101869831 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXR9 ^@ Similarity ^@ Belongs to the UPF0489 family. http://togogenome.org/gene/13146:LOC101867659 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0D1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC4 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101868099 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3S1 ^@ Similarity ^@ Belongs to the CNKSR family. http://togogenome.org/gene/13146:LOC101878606 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUL8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC6 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101881910 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIPOR family.|||Membrane http://togogenome.org/gene/13146:LOC101880262 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU26 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/13146:LOC101877746 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITX6 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/13146:LOC101871240 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVR8 ^@ Similarity ^@ Belongs to the PI3K p85 subunit family. http://togogenome.org/gene/13146:LOC101880094 ^@ http://purl.uniprot.org/uniprot/A0A8C6N939 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868435 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876235 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SFT2 family.|||May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.|||Membrane http://togogenome.org/gene/13146:LOC101880935 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/13146:LOC101871076 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEG6 ^@ Similarity ^@ Belongs to the TMEM14 family. http://togogenome.org/gene/13146:LOC101875557 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101873857 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101871165 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.|||Membrane http://togogenome.org/gene/13146:LOC101879913 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.|||Mediates the uptake of pyruvate into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101875451 ^@ http://purl.uniprot.org/uniprot/A0A8C6J155 ^@ Subcellular Location Annotation ^@ mitochondrion nucleoid http://togogenome.org/gene/13146:LOC101872256 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101872196 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5R5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. http://togogenome.org/gene/13146:LOC101869599 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0V8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.|||Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.|||Cytoplasm|||Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. http://togogenome.org/gene/13146:LOC101879879 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/13146:LOC101869555 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.|||Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.|||Nucleus|||cytosol http://togogenome.org/gene/13146:LOC101876084 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1Q9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BRE1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101875438 ^@ http://purl.uniprot.org/uniprot/A0A8C6J910 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/13146:LOC101872408 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITI0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.|||Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. http://togogenome.org/gene/13146:LOC101878241 ^@ http://purl.uniprot.org/uniprot/A0A8C6INI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG2 family.|||Endoplasmic reticulum membrane|||Lipid droplet|||Preautophagosomal structure membrane http://togogenome.org/gene/13146:LOC101870144 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2U7 ^@ Similarity ^@ Belongs to the eukaryotic NMN adenylyltransferase family. http://togogenome.org/gene/13146:LOC101871961 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/13146:LOC101868131 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPN5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||Component of the 40S ribosomal subunit. http://togogenome.org/gene/13146:LOC101872183 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA8 subunit family.|||Mitochondrion inner membrane|||Mitochondrion intermembrane space http://togogenome.org/gene/13146:LOC101872683 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8P2 ^@ Similarity ^@ Belongs to the PROTOR family. http://togogenome.org/gene/13146:LOC101874205 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1W0 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/13146:LOC101874584 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSD5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101873827 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYZ7 ^@ Function ^@ Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/13146:LOC101881801 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMN6 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/13146:LOC101870956 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9Z1 ^@ Similarity ^@ Belongs to the vir family. http://togogenome.org/gene/13146:LOC101878869 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ31 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neurexophilin family.|||May be signaling molecules that resemble neuropeptides.|||Secreted http://togogenome.org/gene/13146:LOC101879277 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWW7 ^@ Function|||Subcellular Location Annotation ^@ Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.|||cell cortex|||cytoskeleton http://togogenome.org/gene/13146:LOC101879683 ^@ http://purl.uniprot.org/uniprot/A0A8C6JME8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM38 family.|||Membrane|||Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. http://togogenome.org/gene/13146:LOC101870349 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWD2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878905 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRP4 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101881082 ^@ http://purl.uniprot.org/uniprot/A0A8C6INS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SARAF family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101878862 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI03 ^@ Similarity|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Homodimer. http://togogenome.org/gene/13146:LOC101873119 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/13146:LOC101873046 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SecY/SEC61-alpha family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101874449 ^@ http://purl.uniprot.org/uniprot/A0A8C6J749 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101874865 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1Y7 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/13146:LOC101880407 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD64 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/13146:LOC101879255 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101870112 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFK0 ^@ Similarity ^@ Belongs to the PDGF/VEGF growth factor family. http://togogenome.org/gene/13146:LOC101876371 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPB6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101877420 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Q6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101874444 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGR3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/13146:LOC101876869 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the krueppel C2H2-type zinc-finger protein family.|||May be involved in transcriptional regulation.|||Nucleus http://togogenome.org/gene/13146:LOC101877706 ^@ http://purl.uniprot.org/uniprot/A0A8C6IME5 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101881817 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0I2 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/13146:LOC101878278 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI7 ^@ Similarity ^@ Belongs to the UPF0729 family. http://togogenome.org/gene/13146:LOC101871212 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868557 ^@ http://purl.uniprot.org/uniprot/A0A8C6K122 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HARBI1 family.|||Cytoplasm|||Nucleus|||Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity. http://togogenome.org/gene/13146:LOC101871071 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR44 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Early endosome membrane http://togogenome.org/gene/13146:LOC101878079 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGH3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101876842 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRZ5 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/13146:LOC101875224 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Endoplasmic reticulum membrane|||Membrane|||Microsome membrane http://togogenome.org/gene/13146:LOC101876988 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEN6 ^@ Similarity ^@ Belongs to the NARF family. http://togogenome.org/gene/13146:LOC101868550 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUK9 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/13146:LOC101875659 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/13146:LOC101870736 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTR0 ^@ Similarity ^@ Belongs to the NRAMP family. http://togogenome.org/gene/13146:LOC101873748 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDR2 ^@ Similarity ^@ Belongs to the TPPP family. http://togogenome.org/gene/13146:LOC101872310 ^@ http://purl.uniprot.org/uniprot/A0A8C6J821 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP206 family.|||cilium axoneme|||cilium basal body http://togogenome.org/gene/13146:LOC101874995 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEQ5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869928 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL2 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101878799 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parathyroid hormone family.|||Secreted http://togogenome.org/gene/13146:LOC101879516 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRK3 ^@ Similarity ^@ Belongs to the LicD transferase family. http://togogenome.org/gene/13146:LOC101870721 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF71 ^@ Subcellular Location Annotation ^@ Endosome|||Late endosome|||Vesicle http://togogenome.org/gene/13146:LOC101876019 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYP3 ^@ Similarity ^@ Belongs to the SARM1 family. http://togogenome.org/gene/13146:LOC101869556 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYH3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101872994 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0X2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC123 family.|||Cytoplasm|||Required for S phase entry of the cell cycle. http://togogenome.org/gene/13146:LOC101871789 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIR6 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101878090 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7G2 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL11 family.|||Binds directly to 26S ribosomal RNA. http://togogenome.org/gene/13146:LOC101873280 ^@ http://purl.uniprot.org/uniprot/A0A8C6JED2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acyl-CoA dehydrogenase family.|||Homotetramer.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101880697 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTE2|||http://purl.uniprot.org/uniprot/A0A8C6JTM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-54 family.|||Nucleus http://togogenome.org/gene/13146:LOC101876562 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101875158 ^@ http://purl.uniprot.org/uniprot/A0A8C6INK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876453 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Membrane http://togogenome.org/gene/13146:LOC101876185 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/13146:LOC101878674 ^@ http://purl.uniprot.org/uniprot/A0A8C6J932 ^@ Similarity ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. http://togogenome.org/gene/13146:LOC101876941 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101867933 ^@ http://purl.uniprot.org/uniprot/A0A8C6N966 ^@ Similarity ^@ Belongs to the WD repeat WDR24 family. http://togogenome.org/gene/13146:LOC101870049 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITM1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glycosyl hydrolase 2 family.|||Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.|||Lysosome|||Monomer. http://togogenome.org/gene/13146:LOC101881371 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the wntless family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:TVP23B ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP23 family.|||Membrane http://togogenome.org/gene/13146:LOC101873432 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EMP24/GP25L family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||cis-Golgi network membrane http://togogenome.org/gene/13146:LOC101867830 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC12A transporter family.|||Membrane http://togogenome.org/gene/13146:LOC101878010 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101873009 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMI5 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/13146:LOC101870449 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXY4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101873247 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQN8 ^@ Similarity ^@ Belongs to the serpin family. Ov-serpin subfamily. http://togogenome.org/gene/13146:LOC101880230 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY14 ^@ Similarity ^@ Belongs to the PAL/histidase family. http://togogenome.org/gene/13146:LOC101868215 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPE2 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/13146:LOC101881135 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEN7 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family.|||Membrane|||The histidine box domains are involved in binding the catalytic metal ions. http://togogenome.org/gene/13146:LOC101871799 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5M4 ^@ Similarity ^@ Belongs to the EVA1 family. http://togogenome.org/gene/13146:LOC101873404 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK92 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101880423 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJT0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101869525 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRJ4 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily. http://togogenome.org/gene/13146:LOC101872511 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874644 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CWF11 family.|||Nucleus http://togogenome.org/gene/13146:LOC101875222 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWV9 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/13146:LOC101873178 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDL3 ^@ Similarity ^@ Belongs to the bZIP family. Fos subfamily. http://togogenome.org/gene/13146:LOC101872527 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2X9 ^@ Similarity ^@ Belongs to the globin family. http://togogenome.org/gene/13146:LOC101871332 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY14 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101872471 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMIM8 family.|||Membrane http://togogenome.org/gene/13146:LOC101870484 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101875499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL7 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101873717 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DP1 family.|||Membrane http://togogenome.org/gene/13146:LOC101870741 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5G4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-beta family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. http://togogenome.org/gene/13146:LOC101873552 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SRP19 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875167 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879500 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP66 ^@ Similarity ^@ Belongs to the CAF1 family. http://togogenome.org/gene/13146:LOC101875721 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Z6 ^@ Similarity ^@ Belongs to the fibroblast growth factor-binding protein family. http://togogenome.org/gene/13146:LOC101873822 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP12 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101872381 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUK1|||http://purl.uniprot.org/uniprot/A0A8C6IWC7|||http://purl.uniprot.org/uniprot/A0A8C6IWK4 ^@ Subcellular Location Annotation ^@ Membrane|||Mitochondrion inner membrane|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101873233 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK65 ^@ Domain|||Similarity ^@ Belongs to the CAMSAP1 family.|||The CKK domain binds microtubules. http://togogenome.org/gene/13146:LOC101869899 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPIN/STSY family.|||Nucleus http://togogenome.org/gene/13146:LOC101871249 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP50 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/13146:LOC101881066 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasm|||Membrane|||Nucleus membrane|||caveola http://togogenome.org/gene/13146:LOC101879933 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1X4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EMC2 family.|||Component of the ER membrane protein complex (EMC).|||Endoplasmic reticulum membrane|||Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. http://togogenome.org/gene/13146:LOC101879411 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQM5 ^@ Similarity ^@ Belongs to the YOS1 family. http://togogenome.org/gene/13146:LOC101871867 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFA3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Nudix hydrolase family. CPSF5 subfamily.|||Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.|||Cytoplasm|||Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.|||Nucleus http://togogenome.org/gene/13146:LOC101872902 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101879283 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGD8 ^@ Similarity ^@ Belongs to the TMEM121 family. http://togogenome.org/gene/13146:LOC101880637 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Z4 ^@ Subcellular Location Annotation ^@ Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101875383 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGK8 ^@ Cofactor|||Similarity ^@ Belongs to the arginase family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/13146:LOC101876446 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Cytoplasm|||RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA. http://togogenome.org/gene/13146:LOC101869062 ^@ http://purl.uniprot.org/uniprot/A0A8C6N704 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dienelactone hydrolase family.|||cytosol http://togogenome.org/gene/13146:LOC101873933 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISF9 ^@ Similarity|||Subunit ^@ Belongs to the avian keratin family.|||The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides. http://togogenome.org/gene/13146:LOC101872697 ^@ http://purl.uniprot.org/uniprot/A0A8C6K307 ^@ Similarity ^@ Belongs to the caprin family. http://togogenome.org/gene/13146:LOC101869548 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF85 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/13146:LOC106023616 ^@ http://purl.uniprot.org/uniprot/A0A8C6J184 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101871097 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXN2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Cytoplasm|||Membrane|||nucleolus http://togogenome.org/gene/13146:LOC101879635 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEE5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer.|||Secreted http://togogenome.org/gene/13146:LOC101870037 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878676 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101879206 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7D9 ^@ Similarity ^@ Belongs to the UPF0538 family. http://togogenome.org/gene/13146:LOC101881209 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU35 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101870450 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 14 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101878422 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM41 family.|||Membrane http://togogenome.org/gene/13146:LOC101873929 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX97 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/13146:LOC101876901 ^@ http://purl.uniprot.org/uniprot/A0A8C6J125 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the parvin family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101870291 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Q7 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101876229 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase D subunit family.|||clathrin-coated vesicle membrane http://togogenome.org/gene/13146:LOC101871042 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVI7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||nucleolus|||nucleoplasm http://togogenome.org/gene/13146:LOC101881326 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQJ5 ^@ Similarity ^@ Belongs to the RANBP9/10 family. http://togogenome.org/gene/13146:LOC101877813 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDL8 ^@ Similarity ^@ Belongs to the peptidase A1 family. http://togogenome.org/gene/13146:LOC101867652 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRR5 ^@ Similarity ^@ Belongs to the mTERF family. http://togogenome.org/gene/13146:LOC101877941 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNJ8 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/13146:LOC101871704 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLZ8 ^@ Function|||Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.|||Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device. http://togogenome.org/gene/13146:LOC101871902 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2L4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PROPPIN family.|||Preautophagosomal structure membrane http://togogenome.org/gene/13146:LOC101872390 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3K6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101874756 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILJ7 ^@ Function|||Subcellular Location Annotation ^@ Golgi apparatus membrane|||Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.|||Membrane http://togogenome.org/gene/13146:LOC101873364 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Membrane http://togogenome.org/gene/13146:LOC101875594 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR21 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin light chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||coated pit http://togogenome.org/gene/13146:LOC101872564 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPI2 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/13146:LOC101878692 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/13146:LOC101876388 ^@ http://purl.uniprot.org/uniprot/A0A8C6K474 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. http://togogenome.org/gene/13146:LOC101870318 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDY3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101869037 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG36 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101878842 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIL7 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/13146:LOC101881149 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Z4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Nucleus|||Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.|||Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'. http://togogenome.org/gene/13146:LOC101875204 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDC7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tissue factor family.|||Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.|||Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII. http://togogenome.org/gene/13146:LOC101870737 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYU2 ^@ Similarity ^@ Belongs to the PMEL/NMB family. http://togogenome.org/gene/13146:LOC101876751 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRJ1 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101869422 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKY6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS7 family. http://togogenome.org/gene/13146:LOC101881027 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4K1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/13146:LOC101874196 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB17 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101877906 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SIX/Sine oculis homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101869996 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZU3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872046 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Mitochondrion|||Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits. http://togogenome.org/gene/13146:LOC101868802 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepSecS family.|||Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm|||Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer. http://togogenome.org/gene/13146:LOC101876232 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/13146:LOC101881812 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ01 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptotagmin family.|||Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.|||May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.|||Membrane|||chromaffin granule membrane|||synaptic vesicle membrane http://togogenome.org/gene/13146:LOC101879436 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW03 ^@ Similarity ^@ Belongs to the ric-3 family. http://togogenome.org/gene/13146:LOC101869005 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSZ4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. http://togogenome.org/gene/13146:LOC101871910 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/13146:LOC101878798 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HNF1 homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101873584 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Bcl-2 family.|||Cytoplasm|||Endoplasmic reticulum membrane|||Membrane|||Mitochondrion outer membrane|||Nucleus membrane http://togogenome.org/gene/13146:LOC101877798 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEV7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.|||Binds 2 magnesium ions per subunit.|||Nucleus http://togogenome.org/gene/13146:LOC101877632 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879656 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1K3|||http://purl.uniprot.org/uniprot/A0A8C6K535 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B family. http://togogenome.org/gene/13146:LOC101875635 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RPF2 family.|||nucleolus http://togogenome.org/gene/13146:LOC101871151 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0X8 ^@ Similarity ^@ Belongs to the TPD52 family. http://togogenome.org/gene/13146:LOC101874264 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. BCS1 subfamily.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101876969 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD18 ^@ Subcellular Location Annotation ^@ Nucleus|||Perikaryon|||axon http://togogenome.org/gene/13146:LOC101875502 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDF2 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/13146:LOC101873568 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY52 ^@ Similarity ^@ Belongs to the UFL1 family. http://togogenome.org/gene/13146:LOC101869662 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYW0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptogyrin family.|||Membrane http://togogenome.org/gene/13146:LOC101878231 ^@ http://purl.uniprot.org/uniprot/A0A8C6N666 ^@ Subcellular Location Annotation ^@ Cleavage furrow|||Endosome membrane|||Membrane|||Midbody|||Recycling endosome membrane http://togogenome.org/gene/13146:LOC101876344 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.|||Nucleus http://togogenome.org/gene/13146:LOC101877611 ^@ http://purl.uniprot.org/uniprot/A0A8C6K587 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat NOL10/ENP2 family.|||nucleolus http://togogenome.org/gene/13146:LOC101868552 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family.|||Secreted http://togogenome.org/gene/13146:LOC101874154 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrimidine 5'-nucleotidase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101872884 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGU1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NTAQ1 family.|||Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.|||Monomer. http://togogenome.org/gene/13146:LOC101878540 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWU9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101880413 ^@ http://purl.uniprot.org/uniprot/A0A8C6N780 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/13146:LOC101871081 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW54 ^@ Similarity ^@ Belongs to the TBP family. http://togogenome.org/gene/13146:LOC101873259 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2K7 ^@ Function|||Similarity ^@ Belongs to the DNA glycosylase MPG family.|||Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions. http://togogenome.org/gene/13146:LOC101875618 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101877160 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4R7 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/13146:LOC101869728 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1N5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.|||Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.|||nucleolus http://togogenome.org/gene/13146:LOC101881198 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6V5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase T2 family.|||Lysosome lumen http://togogenome.org/gene/13146:LOC101878370 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPH0 ^@ Similarity ^@ Belongs to the importin alpha family. http://togogenome.org/gene/13146:LOC101876478 ^@ http://purl.uniprot.org/uniprot/A0A8C6K417 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TBCA family.|||Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.|||Tubulin-folding protein; involved in the early step of the tubulin folding pathway.|||cytoskeleton http://togogenome.org/gene/13146:LOC101875306 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clarin family.|||Membrane http://togogenome.org/gene/13146:LOC101867681 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKZ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II (RNAPII).|||Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/13146:LOC101881567 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP96 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/13146:LOC101873632 ^@ http://purl.uniprot.org/uniprot/A0A8C6J486 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAM family.|||Membrane http://togogenome.org/gene/13146:LOC101875846 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Z7 ^@ Similarity ^@ Belongs to the NCBP3 family. http://togogenome.org/gene/13146:SOD2 ^@ http://purl.uniprot.org/uniprot/Q802D9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems.|||Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.|||Homotetramer.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101868877 ^@ http://purl.uniprot.org/uniprot/A0A8C6J449 ^@ Similarity ^@ Belongs to the CYFIP family. http://togogenome.org/gene/13146:LOC101879835 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COQ9 family.|||Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.|||Mitochondrion http://togogenome.org/gene/13146:LOC101881187 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101869610 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZB2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101873780 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF44 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/13146:LOC101877379 ^@ http://purl.uniprot.org/uniprot/A0A8C6N732 ^@ Domain|||Subcellular Location Annotation ^@ The N-terminal C2 domain associates with lipid membranes upon calcium binding.|||cytosol http://togogenome.org/gene/13146:LOC101872857 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4T1|||http://purl.uniprot.org/uniprot/A0A8C6J5P3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.|||Belongs to the NPR3 family.|||Lysosome http://togogenome.org/gene/13146:LOC101880990 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M10A family.|||Secreted http://togogenome.org/gene/13146:LOC101873639 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCM9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101879184 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSI7 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. http://togogenome.org/gene/13146:LOC101874155 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAQ3 ^@ Similarity ^@ Belongs to the galactose-3-O-sulfotransferase family. http://togogenome.org/gene/13146:LOC101871067 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDJ3 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/13146:LOC101871114 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRP5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homodimer; disulfide-linked. http://togogenome.org/gene/13146:LOC101875440 ^@ http://purl.uniprot.org/uniprot/A0A8C6J809 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101867640 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAG1 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/13146:LOC101871294 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101880295 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWB2 ^@ Similarity ^@ Belongs to the SVAP1 family. http://togogenome.org/gene/13146:LOC101875034 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TADA1 family.|||Nucleus|||Probably involved in transcriptional regulation. http://togogenome.org/gene/13146:LOC101871968 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101881324 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBH1 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/13146:LOC101872319 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HesB/IscA family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101876886 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTX2 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/13146:LOC101868316 ^@ http://purl.uniprot.org/uniprot/A0A8C6J942 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine). http://togogenome.org/gene/13146:LOC101875295 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILN3 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/13146:LOC101877452 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW26 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferrin family.|||Monomer.|||Secreted http://togogenome.org/gene/13146:LOC101873468 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/13146:LOC101868029 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAX1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 21 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101876792 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.|||centriole http://togogenome.org/gene/13146:LOC101870401 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQX1 ^@ Subcellular Location Annotation ^@ Synapse http://togogenome.org/gene/13146:LOC101876490 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1U6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/13146:LOC101868419 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.|||Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. http://togogenome.org/gene/13146:LOC101881932 ^@ http://purl.uniprot.org/uniprot/A0A8C6INZ6 ^@ Cofactor|||Similarity ^@ Belongs to the paraoxonase family.|||Binds 2 calcium ions per subunit. http://togogenome.org/gene/13146:LOC101872808 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M14 family.|||cytosol http://togogenome.org/gene/13146:LOC101881483 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYM1 ^@ Similarity ^@ Belongs to the RING-box family. http://togogenome.org/gene/13146:LOC101880393 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7M6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP SmB/SmN family.|||Nucleus http://togogenome.org/gene/13146:LOC101880585 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101873999 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3I1 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/13146:LOC101875030 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFU5 ^@ Similarity ^@ Belongs to the FAM102 family. http://togogenome.org/gene/13146:LOC101876468 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGU2 ^@ Similarity ^@ Belongs to the TENT family. http://togogenome.org/gene/13146:LOC101871699 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metaxin family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101876170 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWK6 ^@ Similarity ^@ Belongs to the CARF family. http://togogenome.org/gene/13146:LOC101871529 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY86 ^@ Similarity ^@ Belongs to the PHAF1 family. http://togogenome.org/gene/13146:LOC101874847 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRV6 ^@ Similarity ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. http://togogenome.org/gene/13146:LOC101880188 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101877628 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5C7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/13146:LOC101877843 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3B2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101872402 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101873726 ^@ http://purl.uniprot.org/uniprot/A0A8C6K332 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101878064 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRD2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101881031 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101878326 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IL-10 family.|||Immune regulatory cytokine.|||Secreted http://togogenome.org/gene/13146:LOC101878924 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STEAP family.|||Endosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101867817 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY99 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/13146:LOC101877189 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITW6 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/13146:LOC101868816 ^@ http://purl.uniprot.org/uniprot/A0A8C6K511 ^@ Similarity ^@ Belongs to the ATG8 family. http://togogenome.org/gene/13146:LOC101868795 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAS7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101876431 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872307 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT10 family.|||Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101867873 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYX6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101874054 ^@ http://purl.uniprot.org/uniprot/A0A8C6N672 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Component of the ribosome. http://togogenome.org/gene/13146:LOC101869921 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KHDRBS family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101879221 ^@ http://purl.uniprot.org/uniprot/A0A8C6N712 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 56 family. http://togogenome.org/gene/13146:LOC101869449 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQF3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101880382 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the teashirt C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/13146:LOC101880370 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXR8 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/13146:LOC101869626 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM45 family.|||Membrane http://togogenome.org/gene/13146:LOC101877116 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJY0 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870568 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8B9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NOA36 family.|||nucleolus http://togogenome.org/gene/13146:LOC101874765 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCE4 ^@ Similarity ^@ Belongs to the RCAN family. http://togogenome.org/gene/13146:LOC101870814 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TAF9 family. CENP-S/MHF1 subfamily.|||Nucleus|||kinetochore http://togogenome.org/gene/13146:LOC101868823 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJR1 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/13146:LOC101875107 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILN5 ^@ Similarity ^@ Belongs to the ITPK1 family. http://togogenome.org/gene/13146:LOC101877055 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYK7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRH family.|||Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.|||Secreted http://togogenome.org/gene/13146:LOC101881766 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTL5 ^@ Similarity ^@ Belongs to the nucleobindin family. http://togogenome.org/gene/13146:LOC101880149 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHD9 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101881206 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 29 family.|||Membrane http://togogenome.org/gene/13146:LOC101878863 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDV3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.|||Belongs to the ALG6/ALG8 glucosyltransferase family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101873461 ^@ http://purl.uniprot.org/uniprot/A0A8C6K184 ^@ Similarity ^@ Belongs to the SMEK family. http://togogenome.org/gene/13146:LOC101873842 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB45|||http://purl.uniprot.org/uniprot/A0A8C6JBH1|||http://purl.uniprot.org/uniprot/A0A8C6JBS8|||http://purl.uniprot.org/uniprot/A0A8C6JE49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101873160 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQC2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COQ7 family.|||Binds 2 iron ions per subunit.|||Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. Interacts with ADCK4 and COQ6. Interacts with COQ9.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101874563 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAZ2 ^@ Similarity ^@ Belongs to the SEC2 family. http://togogenome.org/gene/13146:LOC101878637 ^@ http://purl.uniprot.org/uniprot/A0A8C6N933 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/13146:LOC101879937 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NKD family.|||Cell autonomous antagonist of the canonical Wnt signaling pathway.|||Cell membrane|||Cytoplasm|||Membrane http://togogenome.org/gene/13146:LOC101871701 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQM1 ^@ Similarity ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/13146:LOC101880554 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKI8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101870850 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWG2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101876685 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone deacetylase family. HD Type 1 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101873286 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPI8 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:TXN ^@ http://purl.uniprot.org/uniprot/Q802D7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/13146:LOC101873258 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ07 ^@ Similarity ^@ Belongs to the pellino family. http://togogenome.org/gene/13146:LOC101872896 ^@ http://purl.uniprot.org/uniprot/A0A8C6J210 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfatase family.|||Binds 1 Ca(2+) ion per subunit.|||Cell surface|||Endoplasmic reticulum|||Golgi stack|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/13146:LOC101876557 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJV7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAF1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101872174 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8I9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.|||Endoplasmic reticulum membrane|||Microsome membrane http://togogenome.org/gene/13146:LOC101871869 ^@ http://purl.uniprot.org/uniprot/A0A8C6J513 ^@ Similarity ^@ Belongs to the FAM234 family. http://togogenome.org/gene/13146:LOC101870138 ^@ http://purl.uniprot.org/uniprot/A0A8C6K420 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871412 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAR6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875200 ^@ http://purl.uniprot.org/uniprot/A0A8C6J131 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101868027 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H2 subunit B family.|||Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.|||Nucleus|||The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C. http://togogenome.org/gene/13146:LOC101871130 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/13146:LOC101874012 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTD4 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/13146:LOC101881074 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ14 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/13146:LOC101878051 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0W8 ^@ Similarity ^@ Belongs to the NAD kinase family. http://togogenome.org/gene/13146:LOC101876109 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4W1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101876061 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-2-alpha family.|||Stress granule http://togogenome.org/gene/13146:LOC101871430 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.|||Membrane http://togogenome.org/gene/13146:LOC101874167 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3X8 ^@ Similarity|||Subunit ^@ In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.|||In the N-terminal section; belongs to the ubiquitin family.|||Ribosomal protein S27a is part of the 40S ribosomal subunit. http://togogenome.org/gene/13146:LOC101875468 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM69 ^@ Similarity ^@ Belongs to the SBNO family. http://togogenome.org/gene/13146:LOC101874287 ^@ http://purl.uniprot.org/uniprot/A0A8C6J888 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101877296 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYJ5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type I cytokine receptor family. Type 4 subfamily.|||Membrane|||Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).|||The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R. http://togogenome.org/gene/13146:LOC101879740 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW71 ^@ Function|||Similarity ^@ Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.|||Belongs to the NMT family. http://togogenome.org/gene/13146:AZIN1 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ08 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/13146:LOC101869218 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV51 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/13146:LOC101871951 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVY6 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/13146:LOC101868694 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL10 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868762 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101873129 ^@ http://purl.uniprot.org/uniprot/A0A8C6K324 ^@ Similarity ^@ Belongs to the D-glutamate cyclase family. http://togogenome.org/gene/13146:LOC101876331 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTG4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase A2 family.|||Binds 1 Ca(2+) ion per subunit.|||Secreted http://togogenome.org/gene/13146:LOC101872640 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTK0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101868412 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I 75 kDa subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101881684 ^@ http://purl.uniprot.org/uniprot/A0A8C6J721 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BCL9 family.|||Nucleus http://togogenome.org/gene/13146:LOC101876649 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family.|||Nucleus|||Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. http://togogenome.org/gene/13146:LOC101875545 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEK3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/13146:LOC101879704 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/13146:LOC101868924 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCV1 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101876101 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH13 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL24 family. http://togogenome.org/gene/13146:LOC101873886 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7Q2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876234 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101877288 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872298 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OSTC family.|||Component of the oligosaccharyltransferase (OST) complex.|||Membrane|||Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. http://togogenome.org/gene/13146:LOC101876675 ^@ http://purl.uniprot.org/uniprot/A0A8C6N636 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM208 family.|||Endoplasmic reticulum membrane|||May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.|||Membrane http://togogenome.org/gene/13146:LOC101878053 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA63 ^@ Similarity ^@ Belongs to the eukaryotic/archaeal RNase P protein component 3 family. http://togogenome.org/gene/13146:LOC101870104 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT32 ^@ Subcellular Location Annotation ^@ Z line http://togogenome.org/gene/13146:LOC101878298 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R5 ^@ Similarity ^@ Belongs to the TIP41 family. http://togogenome.org/gene/13146:LOC101870438 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7A8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Integrator subunit 10 family.|||Nucleus http://togogenome.org/gene/13146:LOC101868578 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYP7 ^@ Similarity ^@ Belongs to the SKI family. http://togogenome.org/gene/13146:LOC101875881 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5R5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101881876 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2M0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/13146:LOC101875907 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP82 ^@ Similarity ^@ Belongs to the BZW family. http://togogenome.org/gene/13146:LOC101874502 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPSB family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101878652 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXJ3 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/13146:LOC101871608 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX64 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101872901 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane http://togogenome.org/gene/13146:LOC101881507 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFC4 ^@ Similarity ^@ Belongs to the SH2B adapter family. http://togogenome.org/gene/13146:LOC101880091 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPG5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA-intron endonuclease family.|||Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.|||Nucleus http://togogenome.org/gene/13146:LOC101873499 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6E8 ^@ Similarity ^@ Belongs to the FAM91 family. http://togogenome.org/gene/13146:LOC101867839 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVD5 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101871579 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Endoplasmic reticulum membrane|||Membrane|||Peroxisome membrane|||Vesicle http://togogenome.org/gene/13146:RNASEH1 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVS7 ^@ Function|||Similarity ^@ Belongs to the RNase H family.|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. http://togogenome.org/gene/13146:LOC101874377 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/13146:LOC101868656 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptophysin/synaptobrevin family.|||Membrane http://togogenome.org/gene/13146:LOC101874537 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX63 ^@ Similarity ^@ Belongs to the LSM14 family. http://togogenome.org/gene/13146:LOC101880702 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Membrane http://togogenome.org/gene/13146:LOC101871737 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFQ7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/13146:LOC101870732 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU31 ^@ Similarity ^@ Belongs to the GST superfamily. Alpha family. http://togogenome.org/gene/13146:LOC101873852 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXG8 ^@ Cofactor ^@ Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain. http://togogenome.org/gene/13146:LOC101880650 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHC8 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101873244 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISW7 ^@ Similarity ^@ In the C-terminal section; belongs to the sulfate adenylyltransferase family.|||In the N-terminal section; belongs to the APS kinase family. http://togogenome.org/gene/13146:LOC101874933 ^@ http://purl.uniprot.org/uniprot/A0A8C6N904 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878857 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTF3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/13146:LOC101876414 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABITRAM family.|||growth cone|||lamellipodium http://togogenome.org/gene/13146:LOC101877044 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UNC119-binding protein family.|||Cytoplasm|||cilium http://togogenome.org/gene/13146:LOC101876330 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNP8 ^@ Cofactor|||Similarity ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/13146:LOC101874358 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1U5 ^@ Similarity ^@ Belongs to the PPP4R2 family. http://togogenome.org/gene/13146:LOC101874021 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1R9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H4 family.|||Chromosome|||Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101874354 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC72 ^@ Similarity ^@ Belongs to the CD225/Dispanin family. http://togogenome.org/gene/13146:LOC101879498 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKF4 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. http://togogenome.org/gene/13146:LOC101868983 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4J2 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/13146:LOC101873756 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ubiquitin-activating E1 family.|||Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.|||Nucleus|||The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. http://togogenome.org/gene/13146:LOC101871063 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VOPP1/ECOP family.|||Cytoplasmic vesicle membrane|||Membrane http://togogenome.org/gene/13146:LOC101874777 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY83 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/13146:LOC101870262 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0T5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101880444 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDE1 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101872303 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876907 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDU1 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/13146:LOC101872040 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101876559 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFT7|||http://purl.uniprot.org/uniprot/A0A8C6JI47 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.|||In the C-terminal section; belongs to the MoeA family.|||In the N-terminal section; belongs to the MoaB/Mog family. http://togogenome.org/gene/13146:LOC101875219 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101877589 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY61 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101875186 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF91|||http://purl.uniprot.org/uniprot/A0A8C6NBM3 ^@ Subcellular Location Annotation ^@ Membrane|||cytoskeleton http://togogenome.org/gene/13146:LOC101875220 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXL0 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. http://togogenome.org/gene/13146:LOC101881754 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2W3 ^@ Subcellular Location Annotation ^@ Cytoplasm|||dendrite http://togogenome.org/gene/13146:LOC101879582 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868523 ^@ http://purl.uniprot.org/uniprot/A0A8C6K367 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101880489 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF06 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL2 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane|||The C-terminal di-lysine motif may confer endoplasmic reticulum localization. http://togogenome.org/gene/13146:LOC101868225 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7P2 ^@ Similarity|||Subunit ^@ Belongs to the avian keratin family.|||The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides. http://togogenome.org/gene/13146:LOC101869723 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879533 ^@ http://purl.uniprot.org/uniprot/A0A8C6JII4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C. http://togogenome.org/gene/13146:LOC101870587 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9I3 ^@ Similarity ^@ Belongs to the DCP1 family. http://togogenome.org/gene/13146:LOC101878742 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2F4 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. http://togogenome.org/gene/13146:LOC101875401 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSB6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871103 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1Z1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the junctophilin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.|||Membrane http://togogenome.org/gene/13146:LOC101879334 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPB4 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/13146:LOC101878136 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD83 ^@ Function|||Similarity ^@ Belongs to the GST superfamily. Omega family.|||Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA). http://togogenome.org/gene/13146:LOC101871098 ^@ http://purl.uniprot.org/uniprot/A0A8C6J066 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Secreted http://togogenome.org/gene/13146:LOC101868294 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE48 ^@ Similarity ^@ Belongs to the eIF-2B gamma/epsilon subunits family. http://togogenome.org/gene/13146:LOC101878283 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPY1 ^@ Function ^@ Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein. http://togogenome.org/gene/13146:LOC101881181 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1C8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Interacts with PPIF; the interaction is impaired by CsA.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101872237 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHN9 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/13146:LOC101870043 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Z0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 divalent metal cation per subunit.|||Mitochondrion|||Monomer.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. http://togogenome.org/gene/13146:LOC101878254 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQV2 ^@ Similarity ^@ Belongs to the actin family. ARP3 subfamily. http://togogenome.org/gene/13146:LOC101870014 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPC9 RNA polymerase subunit family.|||Nucleus http://togogenome.org/gene/13146:LOC101878945 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV57 ^@ Function|||Similarity ^@ Belongs to the TFIIE alpha subunit family.|||Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. http://togogenome.org/gene/13146:LOC101878958 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI06 ^@ Function|||Similarity ^@ Belongs to the methylmalonyl-CoA mutase family.|||Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle. http://togogenome.org/gene/13146:LOC101873216 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI14 ^@ Similarity ^@ Belongs to the TTC36 family. http://togogenome.org/gene/13146:LOC101873211 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIU8 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/13146:LOC101878588 ^@ http://purl.uniprot.org/uniprot/A0A8C6N727 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the INSIG family.|||Endoplasmic reticulum membrane|||Mediates feedback control of cholesterol synthesis.|||Membrane http://togogenome.org/gene/13146:LOC101873394 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9K2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.|||Nucleus http://togogenome.org/gene/13146:LOC101868761 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874505 ^@ http://purl.uniprot.org/uniprot/A0A8C6K335 ^@ Similarity ^@ Belongs to the dihydrofolate reductase family. http://togogenome.org/gene/13146:LOC101872838 ^@ http://purl.uniprot.org/uniprot/A0A8C6K9V2 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101869915 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPY5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily. http://togogenome.org/gene/13146:LOC101872547 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTF2H2 family.|||Nucleus http://togogenome.org/gene/13146:LOC101880242 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCF7 ^@ Function|||Similarity ^@ Belongs to the RCAN family.|||Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development. http://togogenome.org/gene/13146:LOC101877410 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hook family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101879350 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNP1|||http://purl.uniprot.org/uniprot/A0A8C6JR73 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101879459 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5I1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the snRNP Sm proteins family.|||Binds specifically to the 3'-terminal U-tract of U6 snRNA.|||LSm subunits form a heteromer with a doughnut shape.|||Nucleus http://togogenome.org/gene/13146:LOC101877080 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY50 ^@ Similarity|||Subunit ^@ Belongs to the peptidase C19 family. USP14/UBP6 subfamily.|||Homodimer (Potential). Associates with the 26S proteasome. Interacts with FANCC, CXCR4 and ERN1. Interacts with TRIM14; this interaction recruits USP14 to cleave ubiquitin chains of CGAS. http://togogenome.org/gene/13146:LOC101879178 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC94 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101868459 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSB0 ^@ Function|||Similarity ^@ Belongs to the APC4 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. http://togogenome.org/gene/13146:LOC101868714 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUT0 ^@ Similarity ^@ Belongs to the interleukin-1 receptor family. http://togogenome.org/gene/13146:LOC101868601 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101881032 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCW1 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. http://togogenome.org/gene/13146:LOC101877649 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5X6 ^@ Similarity|||Subunit ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Interacts with MAPK8IP2. http://togogenome.org/gene/13146:LOC101870446 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101872449 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MICOS complex subunit Mic10 family.|||Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.|||Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101876668 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUN1 ^@ Similarity ^@ Belongs to the CEMIP family. http://togogenome.org/gene/13146:LOC101872194 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYW1 ^@ Subcellular Location Annotation ^@ extracellular matrix http://togogenome.org/gene/13146:LOC101879032 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101876496 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQT7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Mitochondrion matrix|||NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues. http://togogenome.org/gene/13146:LOC101875462 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXB5 ^@ Similarity ^@ Belongs to the taxilin family. http://togogenome.org/gene/13146:LOC101868687 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8H8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UTP11 family.|||Component of the ribosomal small subunit (SSU) processome.|||Involved in nucleolar processing of pre-18S ribosomal RNA.|||nucleolus http://togogenome.org/gene/13146:LOC101869550 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874619 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUU0|||http://purl.uniprot.org/uniprot/A0A8C6IWK0 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/13146:LOC101870008 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXU1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101872117 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SPOT14 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101876930 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFU9 ^@ Similarity ^@ Belongs to the RRM CPEB family. http://togogenome.org/gene/13146:LOC101877542 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISI1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868872 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. MFSD6 family.|||Membrane http://togogenome.org/gene/13146:LOC101878451 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND67 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL22 family. http://togogenome.org/gene/13146:LOC101875759 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQD5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101874746 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ68 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101878321 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SWD2 family.|||Nucleus http://togogenome.org/gene/13146:LOC101880240 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the APC5 family.|||Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.|||spindle http://togogenome.org/gene/13146:LOC101878015 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1Y8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat DCAF13/WDSOF1 family.|||nucleolus http://togogenome.org/gene/13146:LOC101880830 ^@ http://purl.uniprot.org/uniprot/A0A8C6INM1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870095 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQW8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101874373 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPC4 ^@ Similarity ^@ Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily. http://togogenome.org/gene/13146:LOC101877894 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDV2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101878181 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMDT1/EMRE family.|||Component of the uniplex complex. Interacts (via the transmembrane region) with MCU (via the first transmembrane region); the interaction is direct.|||Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101881102 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HDDC2 family.|||Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).|||Homodimer. http://togogenome.org/gene/13146:LOC101869497 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-CoA oxidase family.|||Peroxisome http://togogenome.org/gene/13146:LOC101868539 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGL2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane|||Nucleus http://togogenome.org/gene/13146:LOC101878477 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGZ5 ^@ Similarity ^@ Belongs to the cytochrome c oxidase VIIa family. http://togogenome.org/gene/13146:LOC101876579 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWA8 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101871717 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDT6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101869175 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer; disulfide-linked.|||Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.|||extracellular matrix http://togogenome.org/gene/13146:LOC101879602 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUM7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family.|||Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.|||Homodimer. The active form is probably a hexamer composed of 3 homodimers. http://togogenome.org/gene/13146:LOC101868337 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ10 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).|||Membrane http://togogenome.org/gene/13146:LOC101878836 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZL8 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101881444 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUQ8 ^@ Function ^@ May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. http://togogenome.org/gene/13146:LOC101875497 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVJ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/13146:LOC101867832 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101871521 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5K9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.|||Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.|||Cell projection|||Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.|||Cytoplasm|||Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. http://togogenome.org/gene/13146:LOC101881524 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CHFR family.|||PML body http://togogenome.org/gene/13146:LOC101878174 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFY2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Cell membrane|||Membrane|||extracellular exosome http://togogenome.org/gene/13146:LOC101867936 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6G1 ^@ Similarity ^@ Belongs to the cullin family. http://togogenome.org/gene/13146:LOC101871905 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 56 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101878792 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878646 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTQ5 ^@ Subcellular Location Annotation ^@ Z line http://togogenome.org/gene/13146:LOC101870368 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7R8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adaptor complexes small subunit family.|||Cytoplasmic vesicle membrane|||Membrane|||Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. http://togogenome.org/gene/13146:LOC101868355 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101871689 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5W2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/13146:LOC101879399 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0I8 ^@ Similarity ^@ Belongs to the TEX28 family. http://togogenome.org/gene/13146:LOC101875803 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLQ9 ^@ Similarity ^@ Belongs to the popeye family. http://togogenome.org/gene/13146:LOC101873139 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCI6 ^@ Similarity ^@ Belongs to the PHYHIP family. http://togogenome.org/gene/13146:LOC101881628 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasm|||Membrane|||This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.|||caveola http://togogenome.org/gene/13146:LOC101879869 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101879364 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCT1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101871570 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWH2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878242 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUS2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101880032 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the selenoprotein K family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101875702 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZF2|||http://purl.uniprot.org/uniprot/A0A8C6K013 ^@ Similarity ^@ Belongs to the TSC-22/Dip/Bun family. http://togogenome.org/gene/13146:LOC101874945 ^@ http://purl.uniprot.org/uniprot/A0A8C6K291 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/13146:LOC101868065 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN00 ^@ Subcellular Location Annotation ^@ Secreted|||Synapse http://togogenome.org/gene/13146:LOC101869653 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COE family.|||Nucleus http://togogenome.org/gene/13146:LOC101879722 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872551 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4R4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZHX family.|||Nucleus http://togogenome.org/gene/13146:LOC101876906 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITJ4 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/13146:LOC101881377 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M10A family.|||extracellular matrix http://togogenome.org/gene/13146:LOC101869757 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDC0 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/13146:LOC101879902 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPD1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878687 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Z3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JUPITER family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101877307 ^@ http://purl.uniprot.org/uniprot/A0A8C6J276 ^@ Similarity ^@ Belongs to the calycin superfamily. Lipocalin family. http://togogenome.org/gene/13146:LOC101868642 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3S4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.|||Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.|||Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.|||Nucleus http://togogenome.org/gene/13146:LOC101878894 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4C3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/13146:LOC101870578 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1B5 ^@ Similarity ^@ Belongs to the ARTD/PARP family. http://togogenome.org/gene/13146:LOC101879725 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLK2 ^@ Similarity ^@ Belongs to the WD repeat TAF5 family. http://togogenome.org/gene/13146:LOC101880135 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2B0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBCE family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101876335 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUT1 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101871795 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Membrane|||The small GTPases Rab are key regulators in vesicle trafficking. http://togogenome.org/gene/13146:LOC101873058 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT54 ^@ Similarity ^@ Belongs to the angiomotin family. http://togogenome.org/gene/13146:LOC101879968 ^@ http://purl.uniprot.org/uniprot/A0A8C6J947 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101870593 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 4 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101877743 ^@ http://purl.uniprot.org/uniprot/A0A8C6N922 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RAG1 family.|||Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).|||Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.|||Homodimer.|||Nucleus|||The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp. http://togogenome.org/gene/13146:LOC101879433 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS4 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871690 ^@ http://purl.uniprot.org/uniprot/A0A8C6J517 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.|||Secreted http://togogenome.org/gene/13146:LOC101872953 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/PBX homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101875614 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873302 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL65 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/13146:LOC101867837 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK69|||http://purl.uniprot.org/uniprot/A0A8C6JN01 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101868307 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQL6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily. Lipase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101879652 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS48 ^@ Similarity ^@ Belongs to the RIMBP family. http://togogenome.org/gene/13146:LOC101881533 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the rad21 family.|||Nucleus http://togogenome.org/gene/13146:LOC101881926 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF87 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101881043 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/13146:LOC101868067 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat Groucho/TLE family.|||Nucleus http://togogenome.org/gene/13146:LOC101875681 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1L5 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. http://togogenome.org/gene/13146:LOC101874803 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5E0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRM6/GCD10 family.|||Heterotetramer.|||Nucleus|||Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. http://togogenome.org/gene/13146:LOC101881344 ^@ http://purl.uniprot.org/uniprot/A0A8C6J689 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.|||Enterostatin has a biological activity as a satiety signal.|||Forms a 1:1 stoichiometric complex with pancreatic lipase.|||Secreted http://togogenome.org/gene/13146:LOC101875647 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAS0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.|||Cytoplasm|||Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.|||Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.|||Nucleus|||perinuclear region http://togogenome.org/gene/13146:LOC101881309 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN24 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat rae1 family.|||spindle pole http://togogenome.org/gene/13146:LOC101875858 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ClpA/ClpB family. Torsin subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101879766 ^@ http://purl.uniprot.org/uniprot/A0A8C6INQ4 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101871678 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c-type heme lyase family.|||Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101877030 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQH6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868729 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUX1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875162 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Y1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/13146:LOC101879667 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI12 ^@ Similarity ^@ Belongs to the MMACHC family. http://togogenome.org/gene/13146:LOC101875626 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NDRG family.|||cytosol http://togogenome.org/gene/13146:LOC101871782 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYL7 ^@ Function|||Similarity ^@ Anti-proliferative protein.|||Belongs to the BTG family. http://togogenome.org/gene/13146:LOC101874396 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP18 family.|||Nucleus speckle http://togogenome.org/gene/13146:LOC101874934 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDJ0|||http://purl.uniprot.org/uniprot/A0A8C6JEJ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876880 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CUT homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101876145 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1E6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SCAMP family.|||Membrane http://togogenome.org/gene/13146:LOC101871854 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISI3 ^@ Subcellular Location Annotation ^@ Nucleus matrix http://togogenome.org/gene/13146:LOC101872289 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY40 ^@ Similarity ^@ Belongs to the peptidase C19 family. http://togogenome.org/gene/13146:LOC101880502 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9R3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.|||Interacts with SLC9A3R1. Interacts with GABARAPL1.|||Membrane http://togogenome.org/gene/13146:LOC101877477 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT80 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the annexin family.|||Cell membrane|||Cytoplasm|||Lateral cell membrane|||Membrane|||Nucleus|||The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.|||cilium http://togogenome.org/gene/13146:LOC101880170 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUN7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101880402 ^@ http://purl.uniprot.org/uniprot/A0A8C6J257 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/13146:LOC101868624 ^@ http://purl.uniprot.org/uniprot/A0A8C6J520 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hedgehog family.|||Cell membrane|||Endoplasmic reticulum membrane|||Golgi apparatus membrane|||Membrane|||Multimer.|||The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.|||The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development. http://togogenome.org/gene/13146:LOC101877984 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFB1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sideroflexin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101869713 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADIP family.|||adherens junction|||centriolar satellite http://togogenome.org/gene/13146:LOC101876233 ^@ http://purl.uniprot.org/uniprot/A0A8C6N908 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101880331 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCE0 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/13146:LOC101876757 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101873631 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU40 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101880296 ^@ http://purl.uniprot.org/uniprot/A0A8C6J802 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101878006 ^@ http://purl.uniprot.org/uniprot/A0A8C6JME6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNIP family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101881909 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3B1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CREC family.|||Golgi apparatus lumen http://togogenome.org/gene/13146:LOC101869270 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXQ8 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/13146:LOC101874353 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCTS1 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868296 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the argonaute family. Ago subfamily.|||P-body|||Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. http://togogenome.org/gene/13146:LOC101874489 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6Q1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101870879 ^@ http://purl.uniprot.org/uniprot/A0A8C6J045 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.|||Membrane|||Monomer and homodimer. http://togogenome.org/gene/13146:LOC101868172 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATG13 family. Metazoan subfamily.|||Preautophagosomal structure http://togogenome.org/gene/13146:LOC101869865 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS48 ^@ Similarity ^@ Belongs to the RRN3 family. http://togogenome.org/gene/13146:LOC101869824 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tango11 family.|||Membrane|||Mitochondrion outer membrane|||Peroxisome|||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. http://togogenome.org/gene/13146:LOC101868866 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF38 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.|||Cytoplasm http://togogenome.org/gene/13146:LOC101878533 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB92 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/13146:LOC101874951 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLU4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAMOX/DASOX family.|||Peroxisome http://togogenome.org/gene/13146:LOC101874401 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869430 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LRRC8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872745 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876301 ^@ http://purl.uniprot.org/uniprot/A0A8C6K242 ^@ Subcellular Location Annotation ^@ Nucleus|||Vesicle|||clathrin-coated pit|||clathrin-coated vesicle http://togogenome.org/gene/13146:LOC101872778 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTD5 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101876158 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101879359 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPQ1 ^@ Domain ^@ The N-terminal C2 domain associates with lipid membranes upon calcium binding. http://togogenome.org/gene/13146:LOC101870733 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY52 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/13146:LOC101880886 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWW9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20A family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/13146:LOC101880972 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1E3 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101871652 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVF7 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/13146:LOC101873794 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7X6 ^@ Similarity|||Subunit ^@ Belongs to the group II decarboxylase family.|||Homodimer. http://togogenome.org/gene/13146:LOC101868857 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBG6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/13146:LOC101872594 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPQ2 ^@ Function|||Similarity ^@ Belongs to the serpin family.|||Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen. http://togogenome.org/gene/13146:LOC101872692 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Nucleus http://togogenome.org/gene/13146:FOXP2 ^@ http://purl.uniprot.org/uniprot/Q6S511 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877641 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5M7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/13146:LOC101878111 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYS6 ^@ Similarity|||Subunit ^@ Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.|||Interacts with PDZK1. http://togogenome.org/gene/13146:LOC101872782 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPS9 ^@ Similarity ^@ Belongs to the NUF2 family. http://togogenome.org/gene/13146:LOC101877152 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB71 ^@ Cofactor|||Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/13146:LOC101867812 ^@ http://purl.uniprot.org/uniprot/A0A8C6J815 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FMR1 family.|||Cell membrane|||Cytoplasmic ribonucleoprotein granule|||Membrane|||Perikaryon|||Presynaptic cell membrane|||Synaptic cell membrane|||axon|||centromere|||dendrite|||dendritic spine|||filopodium tip|||growth cone|||neuron projection|||nucleolus|||perinuclear region|||synaptosome http://togogenome.org/gene/13146:LOC101880195 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynein light chain family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101876794 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEM5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101876517 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 47 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101873921 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.|||Belongs to the DEAD box helicase family. DEAH subfamily.|||Cytoplasm|||Part of the 43S pre-initiation complex (PIC). http://togogenome.org/gene/13146:LOC101874890 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.|||Nucleus http://togogenome.org/gene/13146:LOC101874464 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1F5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101870253 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869528 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP20 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101880235 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBH9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101869234 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRR5 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/13146:LOC101870899 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT42 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. http://togogenome.org/gene/13146:LOC101874841 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE53 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UQCR10/QCR9 family.|||Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.|||Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101874936 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT61 ^@ Similarity ^@ Belongs to the FAM20 family. http://togogenome.org/gene/13146:LOC101876827 ^@ http://purl.uniprot.org/uniprot/A0A8C6INF6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101878896 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6V2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101881863 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV41 ^@ Similarity ^@ Belongs to the FAM102 family. http://togogenome.org/gene/13146:LOC101872149 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK11 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101876736 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6R9 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/13146:LOC101872219 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872528 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBG5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the lunapark family.|||Endoplasmic reticulum membrane|||Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.|||Plays a role in determining ER morphology.|||The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation. http://togogenome.org/gene/13146:LOC101878610 ^@ http://purl.uniprot.org/uniprot/A0A8C6JER2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875009 ^@ http://purl.uniprot.org/uniprot/A0A8C6JER0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the adrenomedullin family.|||Secreted http://togogenome.org/gene/13146:LOC101877245 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.|||Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.|||Monomer. http://togogenome.org/gene/13146:LOC101870439 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIF3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/13146:LOC101878264 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZC2 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/13146:LOC101876989 ^@ http://purl.uniprot.org/uniprot/A0A8C6J770 ^@ Function|||Similarity ^@ Belongs to the parvalbumin family.|||In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions. http://togogenome.org/gene/13146:LOC101870328 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX16 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101872921 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPM3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anoctamin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101879318 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDG3 ^@ Similarity ^@ Belongs to the CCDC90 family. http://togogenome.org/gene/13146:LOC101879437 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101870335 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1U3 ^@ Similarity ^@ Belongs to the proteasome subunit S10 family. http://togogenome.org/gene/13146:LOC101871847 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX55 ^@ Similarity ^@ Belongs to the FAM13 family. http://togogenome.org/gene/13146:LOC101874451 ^@ http://purl.uniprot.org/uniprot/A0A8C6N935 ^@ Similarity ^@ Belongs to the LAPTM4/LAPTM5 transporter family. http://togogenome.org/gene/13146:LOC101867703 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWA5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.|||Cell membrane|||Cell projection|||Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.|||Perikaryon|||Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm. http://togogenome.org/gene/13146:LOC101871123 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4F9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.|||Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.|||Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.|||Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.|||Cytoplasm|||centrosome|||spindle|||spindle pole http://togogenome.org/gene/13146:LOC101871083 ^@ http://purl.uniprot.org/uniprot/A0A8C6J536 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101867643 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND74 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875270 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101873416 ^@ http://purl.uniprot.org/uniprot/A0A8C6INY6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101869404 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CKS family.|||Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.|||Forms a homohexamer that can probably bind six kinase subunits. http://togogenome.org/gene/13146:LOC101874061 ^@ http://purl.uniprot.org/uniprot/A0A8C6J993 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101880777 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQX2 ^@ Subcellular Location Annotation ^@ Early endosome membrane|||Endosome membrane|||Vesicle|||clathrin-coated vesicle|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101879069 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRD3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101876119 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101877329 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIX0 ^@ Similarity ^@ Belongs to the CBP3 family. http://togogenome.org/gene/13146:LOC101872877 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB90 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101876012 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILK6 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.|||Nucleus http://togogenome.org/gene/13146:LOC101868177 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISF9 ^@ Similarity|||Subunit ^@ Belongs to the avian keratin family.|||The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides. http://togogenome.org/gene/13146:LOC101871202 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM55 ^@ Similarity ^@ Belongs to the peptidase S9A family. http://togogenome.org/gene/13146:LOC101872572 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6F6 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101877335 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/13146:LOC101871467 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family.|||May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.|||perinuclear region http://togogenome.org/gene/13146:LOC101874241 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSX7 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. NTM1 family. http://togogenome.org/gene/13146:LOC101877599 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the L6 tetraspanin family.|||Membrane http://togogenome.org/gene/13146:LOC101872308 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STEAP family.|||Endosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101872574 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/13146:LOC101873598 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVG2 ^@ Similarity ^@ Belongs to the NC2 beta/DR1 family. http://togogenome.org/gene/13146:LOC101874160 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZD8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878963 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXE7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TGF-beta family.|||Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.|||Secreted http://togogenome.org/gene/13146:LOC101880114 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101880277 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PHAX family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101880097 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OB-RGRP/VPS55 family.|||Membrane http://togogenome.org/gene/13146:LOC101878349 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH64 ^@ Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Interacts with ATP6V0C.|||Membrane http://togogenome.org/gene/13146:LOC101872843 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101874650 ^@ http://purl.uniprot.org/uniprot/A0A8C6J205 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR0 subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101878334 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFH1 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/13146:LOC101867891 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDC42SE/SPEC family.|||Cell membrane|||Membrane|||cytoskeleton http://togogenome.org/gene/13146:LOC101872861 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT93 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101880689 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFS6 ^@ Similarity ^@ Belongs to the complex I LYR family. http://togogenome.org/gene/13146:LOC101873442 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3L1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878337 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prickle / espinas / testin family.|||focal adhesion http://togogenome.org/gene/13146:LOC101868421 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101869848 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101869417 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101881931 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWK9 ^@ Function ^@ Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. http://togogenome.org/gene/13146:LOC101881318 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQM2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Catalytic component of the tRNA-splicing ligase complex.|||Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.|||Cytoplasm|||Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP. http://togogenome.org/gene/13146:LOC101874010 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCB9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868379 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRQ4 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/13146:LOC101871244 ^@ http://purl.uniprot.org/uniprot/A0A8C6NES2 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101880176 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101881598 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101875637 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPW3 ^@ Similarity ^@ Belongs to the protein prenyltransferase subunit alpha family. http://togogenome.org/gene/13146:LOC101874877 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase subunit 6c family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871838 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB22 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/13146:LOC101871489 ^@ http://purl.uniprot.org/uniprot/A0A8C6J728 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily. http://togogenome.org/gene/13146:LOC101879623 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CPSF4/YTH1 family.|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).|||Component of the cleavage and polyadenylation specificity factor (CPSF) complex.|||Nucleus http://togogenome.org/gene/13146:LOC101881148 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGF2 ^@ Function|||Similarity ^@ Belongs to the BLOC1S5 family.|||Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). http://togogenome.org/gene/13146:LOC101873489 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFH1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/13146:LOC101877617 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEL0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101876536 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.|||Cell membrane http://togogenome.org/gene/13146:LOC101869584 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GGA protein family.|||Early endosome membrane|||Endosome membrane|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101868717 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FUN14 family.|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101881126 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMTC family.|||Endoplasmic reticulum|||Membrane http://togogenome.org/gene/13146:LOC101875298 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNK2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic AdoMetDC family.|||Binds 1 pyruvoyl group covalently per subunit.|||Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels. http://togogenome.org/gene/13146:LOC101872363 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hcp beta-lactamase family.|||Mitochondrion intermembrane space http://togogenome.org/gene/13146:LOC101869800 ^@ http://purl.uniprot.org/uniprot/A0A8C6J204 ^@ Similarity ^@ Belongs to the indoleamine 2,3-dioxygenase family. http://togogenome.org/gene/13146:LOC101870480 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL33 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/13146:LOC101880922 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXN0|||http://purl.uniprot.org/uniprot/A0A8C6K0B5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the fibulin family.|||Homomultimerizes and interacts with various extracellular matrix components.|||Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101877814 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH24 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101878132 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0S0 ^@ Similarity ^@ Belongs to the FAM168 family. http://togogenome.org/gene/13146:LOC101868790 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7L9 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101881678 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBH2 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101871258 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101875309 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7R4 ^@ Similarity ^@ Belongs to the TAF11 family. http://togogenome.org/gene/13146:LOC101872710 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBR4 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/13146:LOC101874909 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW80 ^@ Similarity ^@ Belongs to the centrin family. http://togogenome.org/gene/13146:LOC101871290 ^@ http://purl.uniprot.org/uniprot/A0A8C6J734 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.|||Nucleus|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/13146:LOC101870419 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869035 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNH9 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.|||Membrane http://togogenome.org/gene/13146:LOC101877206 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHZ5 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101879710 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2U3 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/13146:LOC101878024 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the villin/gelsolin family.|||cytoskeleton|||podosome http://togogenome.org/gene/13146:LOC101875292 ^@ http://purl.uniprot.org/uniprot/A0A8C6K847 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/13146:LOC101873237 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC27 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101874431 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2L8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSG1 family.|||Membrane http://togogenome.org/gene/13146:LOC101871668 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHY6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/13146:LOC101875396 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC75 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HAT1 family.|||Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.|||Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac). http://togogenome.org/gene/13146:LOC101874641 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITV4 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/13146:LOC101869231 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875817 ^@ http://purl.uniprot.org/uniprot/A0A8C6K615 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101872368 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8N5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871257 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the borealin family.|||centromere http://togogenome.org/gene/13146:LOC101874657 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0I4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873860 ^@ http://purl.uniprot.org/uniprot/A0A8C6K076 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879995 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX46 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.|||Mitochondrion http://togogenome.org/gene/13146:LOC101869750 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5F8 ^@ Domain|||Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.|||Induces caspases and apoptosis. Counters the protective effect of BCL2.|||Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101875566 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101870436 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWI1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tenascin family. Teneurin subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101870560 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB72 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875353 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIC0 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/13146:LOC101880487 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXB2 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/13146:LOC101873360 ^@ http://purl.uniprot.org/uniprot/A0A8C6INV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868311 ^@ http://purl.uniprot.org/uniprot/A0A8C6KAD3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGM family.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.|||Membrane http://togogenome.org/gene/13146:LOC101878113 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMK1 ^@ Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Cytoplasm|||Membrane http://togogenome.org/gene/13146:LOC101874452 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R4 ^@ Similarity ^@ Belongs to the NUP186/NUP192/NUP205 family. http://togogenome.org/gene/13146:LOC101876058 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ADP-ribosyl cyclase family.|||Membrane http://togogenome.org/gene/13146:LOC101872859 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITC3 ^@ Similarity ^@ Belongs to the UPF0400 (RTT103) family. http://togogenome.org/gene/13146:LOC101877228 ^@ http://purl.uniprot.org/uniprot/A0A8C6K460 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGB family.|||Chromosome http://togogenome.org/gene/13146:LOC101870286 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXN6 ^@ Similarity ^@ Belongs to the carotenoid oxygenase family. http://togogenome.org/gene/13146:LOC101881718 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL43 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101874011 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPJ1 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/13146:LOC101875387 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0I3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101875821 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR65 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101880545 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7T6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877271 ^@ http://purl.uniprot.org/uniprot/A0A8C6K214 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/13146:LOC101871563 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/13146:LOC101871517 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP46 ^@ Similarity ^@ Belongs to the FAM53 family. http://togogenome.org/gene/13146:LOC101873096 ^@ http://purl.uniprot.org/uniprot/A0A8C6K178 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101869758 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101873455 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7S5 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/13146:LOC101876741 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family. Jun subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101869937 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNW family.|||Identified in the spliceosome C complex.|||Involved in pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/13146:LOC101881281 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4J5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Nucleus|||centriole|||cilium http://togogenome.org/gene/13146:LOC101871105 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cytoplasmic vesicle|||G-protein coupled receptor for 5-hydroxytryptamine (serotonin).|||Membrane|||Presynapse|||Synapse|||Vesicle|||axon|||caveola|||dendrite http://togogenome.org/gene/13146:LOC101876264 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYX8 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/13146:LOC101876313 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISR1 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/13146:LOC101868994 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDG4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP-alpha family.|||Endoplasmic reticulum membrane|||Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.|||Membrane|||Shows a remarkable charge distribution with the N-terminus being highly negatively charged, and the cytoplasmic C-terminus positively charged.|||TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after completion of the translocation process or may function as a membrane-bound chaperone facilitating folding of translocated proteins. http://togogenome.org/gene/13146:LOC101871444 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTN0 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101874226 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9H2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871069 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1N6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/13146:LOC101869641 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101868603 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0N7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/13146:LOC101871398 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTK3 ^@ Caution|||Subcellular Location Annotation ^@ Endoplasmic reticulum|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Mitochondrion intermembrane space|||Mitochondrion outer membrane|||Rough endoplasmic reticulum|||cilium|||extracellular exosome|||extracellular space http://togogenome.org/gene/13146:LOC101874020 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKR5 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/13146:LOC101881096 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVF9 ^@ Similarity ^@ Belongs to the SMAP family. http://togogenome.org/gene/13146:LOC101869143 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1D4 ^@ Function|||Similarity ^@ Belongs to the pex2/pex10/pex12 family.|||Somewhat implicated in the biogenesis of peroxisomes. http://togogenome.org/gene/13146:LOC101871046 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXB4 ^@ Similarity ^@ Belongs to the SERF family. http://togogenome.org/gene/13146:LOC101868028 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFV2 ^@ Similarity ^@ Belongs to the HUS1 family. http://togogenome.org/gene/13146:LOC101869777 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101880432 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR62 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875208 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNY3 ^@ Subcellular Location Annotation ^@ extracellular matrix http://togogenome.org/gene/13146:LOC101874218 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBG8 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/13146:LOC101881073 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SEC23/SEC24 family. SEC24 subfamily.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Membrane|||cytosol http://togogenome.org/gene/13146:LOC101874023 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101876772 ^@ http://purl.uniprot.org/uniprot/A0A8C6J674 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/13146:LOC101872030 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP12 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/13146:LOC101879597 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC85 family.|||adherens junction http://togogenome.org/gene/13146:LOC101871527 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-50 family.|||Membrane|||Nucleus inner membrane http://togogenome.org/gene/13146:LOC101875787 ^@ http://purl.uniprot.org/uniprot/A0A8C6J697 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Cell membrane|||Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.|||Membrane|||Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.|||Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. http://togogenome.org/gene/13146:LOC101879697 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclin family. Cyclin G subfamily.|||May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.|||Nucleus http://togogenome.org/gene/13146:LOC101872761 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY03 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101880443 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQX7 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/13146:LOC101880065 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSC0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101870380 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGF4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880591 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM44 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TAM41 family.|||Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101873803 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRS8 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/13146:LOC101872732 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT77 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SNF5 family.|||Component of the multiprotein chromatin-remodeling complexes SWI/SNF.|||Nucleus http://togogenome.org/gene/13146:LOC101874611 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SOSS-C family.|||Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).|||Component of the SOSS complex.|||Nucleus http://togogenome.org/gene/13146:LOC101880265 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY13 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||centrosome|||cilium basal body|||perinuclear region|||spindle http://togogenome.org/gene/13146:LOC101875284 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3N0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.|||Peroxisome membrane http://togogenome.org/gene/13146:LOC101881219 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMJ2 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101877576 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS75 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101879777 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJZ1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.|||Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. http://togogenome.org/gene/13146:LOC101880819 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY79 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/13146:LOC101871195 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND95 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/13146:LOC101880021 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDM0 ^@ Similarity ^@ Belongs to the glycerate kinase type-2 family. http://togogenome.org/gene/13146:LOC101875161 ^@ http://purl.uniprot.org/uniprot/A0A8C6J273 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/13146:LOC101877667 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNQ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/13146:LOC101870282 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWE1 ^@ Similarity ^@ Belongs to the guanylate kinase family. http://togogenome.org/gene/13146:LOC101872181 ^@ http://purl.uniprot.org/uniprot/A0A8C6K701 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/13146:LOC101873865 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUD1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORC4 family.|||Component of the origin recognition complex (ORC) that binds origins of replication.|||Nucleus http://togogenome.org/gene/13146:LOC101877555 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8J8 ^@ Similarity ^@ Belongs to the heparin-binding growth factors family. http://togogenome.org/gene/13146:LOC101868525 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCB3 ^@ Similarity ^@ Belongs to the peptidase M14 family. http://togogenome.org/gene/13146:LOC101868861 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNZ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with ARRB1.|||Membrane http://togogenome.org/gene/13146:LOC101874425 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBN8 ^@ Similarity ^@ Belongs to the FAD-binding oxidoreductase/transferase type 4 family. http://togogenome.org/gene/13146:LOC101872391 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 2 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101879084 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEM3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/13146:LOC101869930 ^@ http://purl.uniprot.org/uniprot/A0A8C6K158 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/13146:LOC101878144 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the POC5 family.|||Essential for the assembly of the distal half of centrioles, required for centriole elongation.|||centriole http://togogenome.org/gene/13146:LOC101878453 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2V6 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/13146:LOC101874302 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.|||Belongs to the TBCC family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872397 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Spartan family.|||Chromosome|||Nucleus http://togogenome.org/gene/13146:LOC101875929 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3F4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TNF receptor-associated factor family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101879644 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCS8 ^@ Similarity ^@ Belongs to the adenylate kinase family. http://togogenome.org/gene/13146:LOC101871531 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic mitochondrial porin family.|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101874158 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWW2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Cytoplasmic vesicle membrane|||Membrane|||cytosol|||ruffle membrane|||synaptosome http://togogenome.org/gene/13146:LOC101876735 ^@ http://purl.uniprot.org/uniprot/A0A8C6K124 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101875330 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8U4 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101881261 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8Q9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase V0D/AC39 subunit family.|||Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101871458 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGS8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/13146:LOC101878576 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWQ2 ^@ Subcellular Location Annotation ^@ centrosome http://togogenome.org/gene/13146:LOC101877450 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0239 family.|||Membrane http://togogenome.org/gene/13146:LOC101872344 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SH3RF family.|||lamellipodium|||perinuclear region|||trans-Golgi network http://togogenome.org/gene/13146:LOC101879645 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJB0 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Cytoplasm|||Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.|||Membrane http://togogenome.org/gene/13146:LOC101871451 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISH4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101872102 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101867876 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7T1 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/13146:LOC101878752 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV23 ^@ Similarity ^@ Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. http://togogenome.org/gene/13146:LOC101869441 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR58 ^@ Similarity ^@ Belongs to the CFAP97 family. http://togogenome.org/gene/13146:LOC101871966 ^@ http://purl.uniprot.org/uniprot/A0A8C6IK68 ^@ Similarity ^@ Belongs to the serpin family. Ov-serpin subfamily. http://togogenome.org/gene/13146:LOC101874371 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU01 ^@ Similarity ^@ Belongs to the SNF7 family. http://togogenome.org/gene/13146:LOC101871194 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat EDC4 family.|||P-body http://togogenome.org/gene/13146:LOC101880250 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI30 ^@ Subcellular Location Annotation|||Subunit ^@ Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.|||Secreted http://togogenome.org/gene/13146:LOC101867768 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVH1 ^@ Function|||Similarity ^@ Belongs to the ferritin family.|||Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. http://togogenome.org/gene/13146:LOC101880079 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3R6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the P2X receptor family.|||Functional P2XRs are organized as homomeric and heteromeric trimers.|||Membrane|||Receptor for ATP that acts as a ligand-gated ion channel. http://togogenome.org/gene/13146:LOC101877788 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN20 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eIF-3 subunit D family.|||Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.|||Cytoplasm|||The RNA gate region regulates mRNA cap recognition to prevent promiscuous mRNA-binding before assembly of eif3d into the full eukaryotic translation initiation factor 3 (eIF-3) complex.|||mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7-methylguanosine cap of a subset of mRNAs. http://togogenome.org/gene/13146:LOC101872006 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD26 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101868901 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLA2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily. http://togogenome.org/gene/13146:LOC101878378 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8N1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879148 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0U2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC181 family.|||Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.|||cytoskeleton|||flagellum http://togogenome.org/gene/13146:LOC101880048 ^@ http://purl.uniprot.org/uniprot/A0A8C6INW7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tachykinin family.|||Secreted|||Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. http://togogenome.org/gene/13146:LOC101879844 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A connexon is composed of a hexamer of connexins.|||Belongs to the connexin family. Alpha-type (group II) subfamily.|||Cell membrane|||Membrane|||One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.|||gap junction http://togogenome.org/gene/13146:LOC101868025 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101877311 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0S5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101879633 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SSU72 phosphatase family.|||Nucleus|||Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination. http://togogenome.org/gene/13146:LOC101877356 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM21 ^@ Similarity ^@ Belongs to the dermatan-sulfate isomerase family. http://togogenome.org/gene/13146:LOC101870366 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN7/EIF3M family. CSN7 subfamily.|||Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101877653 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101869278 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRW0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Cytoplasm|||Nucleus|||The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. http://togogenome.org/gene/13146:LOC101876373 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HIT family.|||Cytoplasm|||Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway.|||Homodimer. Associates with components of the exosome multienzyme ribonuclease complex, such as EXOSC3 and EXOSC4. Interacts with NDOR1.|||Nucleus http://togogenome.org/gene/13146:LOC101873848 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UTP23/FCF1 family. FCF1 subfamily.|||nucleolus http://togogenome.org/gene/13146:LOC101870016 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXA2 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/13146:LOC101881091 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5I0 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/13146:LOC101868432 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101867696 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101880104 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWR9 ^@ Cofactor|||Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase family.|||Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. http://togogenome.org/gene/13146:LOC101881687 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKQ3 ^@ Subcellular Location Annotation ^@ Chromosome|||Cytoplasm http://togogenome.org/gene/13146:LOC101870030 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lariat debranching enzyme family.|||Nucleus http://togogenome.org/gene/13146:LOC101869351 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GLI C2H2-type zinc-finger protein family.|||Nucleus http://togogenome.org/gene/13146:LOC101868703 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVZ5 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/13146:LOC106023495 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWH0 ^@ Similarity ^@ Belongs to the FMC1 family. http://togogenome.org/gene/13146:LOC101880318 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2N6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880608 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRF7 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101872779 ^@ http://purl.uniprot.org/uniprot/A0A8C6INY0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101873657 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0V7 ^@ Subcellular Location Annotation ^@ Endosome|||Recycling endosome http://togogenome.org/gene/13146:LOC101870771 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101881576 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE25 ^@ Similarity ^@ Belongs to the glycosyltransferase 92 family. http://togogenome.org/gene/13146:LOC101881527 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PRP38 family.|||May be required for pre-mRNA splicing.|||Nucleus http://togogenome.org/gene/13146:LOC101874019 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYD7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/13146:LOC101871879 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PLAP family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101871017 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1G5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MTFR1 family.|||Mitochondrion|||Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission. http://togogenome.org/gene/13146:LOC101876393 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2M3 ^@ Subcellular Location Annotation ^@ perinuclear region http://togogenome.org/gene/13146:LOC101868697 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Q6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PPP phosphatase family. PP-1 subfamily.|||Cleavage furrow|||Cytoplasm|||Midbody http://togogenome.org/gene/13146:LOC101881761 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW44 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877522 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITL5 ^@ Similarity ^@ Belongs to the MSANTD3 family. http://togogenome.org/gene/13146:LOC101869949 ^@ http://purl.uniprot.org/uniprot/A0A8C6J042 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. http://togogenome.org/gene/13146:LOC101879928 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLD6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily. http://togogenome.org/gene/13146:LOC101869932 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/13146:LOC101880484 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101879151 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP06 ^@ Subcellular Location Annotation ^@ Membrane|||Membrane raft|||Secreted http://togogenome.org/gene/13146:LOC101869247 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSR8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.|||Functions as a zinc transporter.|||Homooligomer.|||Membrane|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101876182 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMK7 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101880601 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2E9 ^@ Subcellular Location Annotation ^@ Cytoplasm|||Nucleus|||Secreted http://togogenome.org/gene/13146:LOC101873826 ^@ http://purl.uniprot.org/uniprot/A0A8C6J261 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferrin family.|||Monomer.|||Secreted http://togogenome.org/gene/13146:LOC101868571 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876436 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NK-2 homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101874297 ^@ http://purl.uniprot.org/uniprot/A0A8C6JII2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 7B2 family.|||Secreted http://togogenome.org/gene/13146:LOC101880758 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI20 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880495 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9R5 ^@ Function|||Similarity ^@ Belongs to the alpha-carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/13146:LOC101880260 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBC3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/13146:LOC101872250 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7X7 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||May be involved in photoreceptor outer segment disk morphogenesis.|||Photoreceptor inner segment http://togogenome.org/gene/13146:LOC101879329 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX75 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101869705 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868846 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HMG-CoA lyase family.|||Homodimer; disulfide-linked. Can also form homotetramers.|||Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism. http://togogenome.org/gene/13146:LOC101868555 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL52|||http://purl.uniprot.org/uniprot/A0A8C6NDF3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily. http://togogenome.org/gene/13146:LOC101872540 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CFAP52 family.|||Cytoplasm|||flagellum http://togogenome.org/gene/13146:LOC101879417 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101870199 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDL2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.|||Belongs to the RNR ribonuclease family. DIS3L2 subfamily.|||Cytoplasm|||P-body|||Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site. http://togogenome.org/gene/13146:LOC101867869 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSQ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with C6orf89.|||Membrane http://togogenome.org/gene/13146:LOC101875019 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101877282 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW96 ^@ Similarity ^@ Belongs to the FAH family. http://togogenome.org/gene/13146:LOC101875380 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLT9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pinin family.|||Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.|||Nucleus speckle|||desmosome http://togogenome.org/gene/13146:LOC101874707 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTH3 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/13146:LOC101874649 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMP-30/CGR1 family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101869477 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cathelicidin family.|||Secreted http://togogenome.org/gene/13146:LOC101875949 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBU9 ^@ Similarity ^@ Belongs to the WD repeat G protein beta family. http://togogenome.org/gene/13146:LOC101875215 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VTI1 family.|||Membrane http://togogenome.org/gene/13146:LOC101880301 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101871831 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ZHX family.|||Nucleus http://togogenome.org/gene/13146:LOC101870532 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872828 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUS4 ^@ Function|||Similarity ^@ As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.|||Belongs to the CIA30 family. http://togogenome.org/gene/13146:LOC101878849 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCS4 ^@ Similarity ^@ Belongs to the DEAD box helicase family. eIF4A subfamily. http://togogenome.org/gene/13146:LOC101868021 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKX9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the EF-1-beta/EF-1-delta family.|||EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.|||EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP. http://togogenome.org/gene/13146:LOC101877779 ^@ http://purl.uniprot.org/uniprot/A0A8C6N915 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 7 family.|||Golgi apparatus membrane|||Membrane|||Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. http://togogenome.org/gene/13146:LOC101877696 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDH0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CALHM family.|||Membrane http://togogenome.org/gene/13146:LOC101878375 ^@ http://purl.uniprot.org/uniprot/A0A8C6N790 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101867835 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWB0 ^@ Similarity ^@ Belongs to the dermatan-sulfate isomerase family. http://togogenome.org/gene/13146:LOC101879210 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9J2 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101873421 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX82 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101876534 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bombesin/neuromedin-B/ranatensin family.|||Secreted http://togogenome.org/gene/13146:LOC101869059 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEW7 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101869895 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCM3 ^@ Similarity ^@ Belongs to the carnitine/choline acetyltransferase family. http://togogenome.org/gene/13146:LOC101871620 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE33 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101876510 ^@ http://purl.uniprot.org/uniprot/A0A8C6J652 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101876031 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5A1 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/13146:LOC101869656 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tubulin polyglutamylase family.|||cilium basal body http://togogenome.org/gene/13146:LOC101879496 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5C2 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/13146:LOC101879780 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the WD repeat LIS1/nudF family.|||Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.|||Dimerization mediated by the LisH domain may be required to activate dynein.|||Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.|||centrosome|||cytoskeleton http://togogenome.org/gene/13146:LOC101873775 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869635 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITI8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101870669 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU36 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/13146:LOC101879297 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1A1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tweety family.|||Cell membrane|||Membrane|||Probable chloride channel. http://togogenome.org/gene/13146:LOC101877517 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR61 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Monomer. Interacts with ANKRD16; the interaction is direct. http://togogenome.org/gene/13146:LOC101881756 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/13146:LOC101878683 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCV0 ^@ Similarity ^@ Belongs to the dysbindin family. http://togogenome.org/gene/13146:LOC101881457 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWD4 ^@ Similarity ^@ Belongs to the ELP6 family. http://togogenome.org/gene/13146:LOC101871323 ^@ http://purl.uniprot.org/uniprot/A0A8C6K094 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel CLIC family.|||Membrane http://togogenome.org/gene/13146:LOC101880814 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA35 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/13146:LOC101873965 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4S6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/13146:LOC101868771 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYD0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S26 family.|||Heterodimer of 2 subunits, IMMPL1 and IMMPL2.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101875568 ^@ http://purl.uniprot.org/uniprot/A0A8C6J321 ^@ Similarity ^@ Belongs to the small GTPase superfamily. Arf family. http://togogenome.org/gene/13146:LOC101869572 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEW6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase G subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101871904 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGN4 ^@ Similarity ^@ Belongs to the CBF/MAK21 family. http://togogenome.org/gene/13146:LOC101879368 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZD4 ^@ Similarity ^@ Belongs to the DeSI family. http://togogenome.org/gene/13146:LOC101877933 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV00 ^@ Similarity ^@ Belongs to the BTG family. http://togogenome.org/gene/13146:LOC101872670 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP77|||http://purl.uniprot.org/uniprot/A0A8C6JUU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tropomyosin family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101872803 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSC1 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL43 family. http://togogenome.org/gene/13146:LOC101879089 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family.|||mitochondrion nucleoid http://togogenome.org/gene/13146:LOC101869609 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPW4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Tango11 family.|||Membrane|||Mitochondrion outer membrane|||Peroxisome|||Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. http://togogenome.org/gene/13146:LOC101881589 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/13146:LOC101879775 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY54 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ COPI-coated vesicle membrane|||Cytoplasm|||Golgi apparatus membrane|||Membrane|||Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.|||The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. http://togogenome.org/gene/13146:LOC101875739 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMQ7 ^@ Function|||Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. http://togogenome.org/gene/13146:LOC101874034 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101881035 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TBP family.|||Nucleus http://togogenome.org/gene/13146:LOC101877958 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Secreted http://togogenome.org/gene/13146:LOC101872800 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868425 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISZ2 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IRF family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleus http://togogenome.org/gene/13146:LOC101877663 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Chromosome|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/13146:LOC101877846 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PSMG1 family.|||Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.|||Cytoplasm|||Forms a heterodimer with psmg2. http://togogenome.org/gene/13146:LOC101881302 ^@ http://purl.uniprot.org/uniprot/A0A8C6K9S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101881370 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZH2 ^@ Subcellular Location Annotation ^@ nucleolus http://togogenome.org/gene/13146:LOC101875575 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Q8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL50 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101875796 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CSN8 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101879756 ^@ http://purl.uniprot.org/uniprot/A0A8C6J618 ^@ Similarity ^@ Belongs to the NDRG family. http://togogenome.org/gene/13146:LOC101867884 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the helicase family. RLR subfamily.|||Cytoplasm http://togogenome.org/gene/13146:LOC101878489 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3J8 ^@ Similarity ^@ Belongs to the 'GDXG' lipolytic enzyme family. http://togogenome.org/gene/13146:LOC101868077 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMB1 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/13146:LOC101872531 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STAM family.|||Early endosome membrane http://togogenome.org/gene/13146:LOC101877928 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat striatin family.|||Membrane http://togogenome.org/gene/13146:LOC101879589 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQQ3 ^@ Function|||Similarity ^@ Belongs to the UFM1 family.|||Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress. http://togogenome.org/gene/13146:LOC101876171 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUG4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101878442 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISM4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the P2X receptor family.|||Functional P2XRs are organized as homomeric and heteromeric trimers.|||Membrane|||Receptor for ATP that acts as a ligand-gated ion channel. http://togogenome.org/gene/13146:LOC101871979 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP71 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/13146:LOC101879536 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic/archaeal RNase P protein component 2 family.|||Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.|||nucleolus http://togogenome.org/gene/13146:LOC101872725 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Early endosome membrane|||Endosome membrane|||Golgi apparatus membrane|||Recycling endosome|||phagosome|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101875931 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101871872 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872764 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAI6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alkaline ceramidase family.|||Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101873099 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily.|||Membrane http://togogenome.org/gene/13146:LOC101872432 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX90 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptotagmin family.|||Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.|||May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.|||Membrane|||chromaffin granule membrane|||synaptic vesicle membrane http://togogenome.org/gene/13146:LOC101878650 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS44 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101873226 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101874959 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWL0 ^@ Function|||Similarity ^@ Belongs to the WD repeat EIF2A family.|||Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. http://togogenome.org/gene/13146:LOC101869167 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bZIP family.|||Nucleus http://togogenome.org/gene/13146:LOC101878462 ^@ http://purl.uniprot.org/uniprot/A0A8C6K246 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acyl-CoA reductase family.|||Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.|||Peroxisome membrane http://togogenome.org/gene/13146:LOC101877076 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITW9|||http://purl.uniprot.org/uniprot/A0A8C6IWV1|||http://purl.uniprot.org/uniprot/A0A8C6N7L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871161 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG14 ^@ Similarity|||Subunit ^@ Belongs to the tectonic family.|||Part of the tectonic-like complex (also named B9 complex). http://togogenome.org/gene/13146:LOC101875547 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPP small subunits family. BET3 subfamily.|||Endoplasmic reticulum|||cis-Golgi network http://togogenome.org/gene/13146:LOC101873821 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGZ2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101876538 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZQ0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101873957 ^@ http://purl.uniprot.org/uniprot/A0A8C6K160 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101872079 ^@ http://purl.uniprot.org/uniprot/A0A8C6K000 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MiT/TFE family.|||Nucleus http://togogenome.org/gene/13146:LOC101876645 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6J5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101872590 ^@ http://purl.uniprot.org/uniprot/A0A8C6K486 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/13146:LOC101876714 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6Y0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868285 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1A0 ^@ Similarity ^@ Belongs to the GADD45 family. http://togogenome.org/gene/13146:LOC101874685 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9E8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101869212 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCR4/nocturin family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101881279 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5N3 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 38 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/13146:LOC101880663 ^@ http://purl.uniprot.org/uniprot/A0A8C6INL1 ^@ Similarity ^@ Belongs to the copine family. http://togogenome.org/gene/13146:LOC101880315 ^@ http://purl.uniprot.org/uniprot/A0A8C6J050 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR3 subfamily.|||Mitochondrion|||Nucleus|||centrosome|||spindle http://togogenome.org/gene/13146:LOC101868098 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC35F solute transporter family.|||Membrane http://togogenome.org/gene/13146:LOC101875797 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0A3 ^@ Similarity ^@ Belongs to the MT-A70-like family. http://togogenome.org/gene/13146:LOC101877945 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 43 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101871873 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA87 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/13146:LOC101871801 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2L4 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871930 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 13 family.|||Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101876277 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/13146:LOC101879861 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQK5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101871324 ^@ http://purl.uniprot.org/uniprot/A0A8C6K074 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the somatostatin family.|||Secreted http://togogenome.org/gene/13146:LOC101879636 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH72 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101876844 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXS8 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/13146:LOC101875498 ^@ http://purl.uniprot.org/uniprot/A0A8C6J068 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Interacts with UHRF2/NIRF.|||May be involved in cell cycle regulation.|||Nucleus http://togogenome.org/gene/13146:LOC101870391 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDIP1/LITAF family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101870042 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0E1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ING family.|||Component of an histone acetyltransferase complex.|||Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.|||Nucleus|||The PHD-type zinc finger mediates the binding to H3K4me3. http://togogenome.org/gene/13146:LOC101880307 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Y1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/13146:LOC101876509 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILZ2 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1. http://togogenome.org/gene/13146:LOC101868996 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AROS family.|||nucleolus http://togogenome.org/gene/13146:LOC101873535 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the enhancer of polycomb family.|||Nucleus http://togogenome.org/gene/13146:LOC101873415 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family. PCH2 subfamily.|||Nucleus|||Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. http://togogenome.org/gene/13146:LOC101879824 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL80 ^@ Similarity ^@ Belongs to the Diphthine--ammonia ligase family. http://togogenome.org/gene/13146:LOC101880531 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome P450 family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101872545 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDQ4 ^@ Similarity ^@ Belongs to the CD36 family. http://togogenome.org/gene/13146:LOC101875878 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9F2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cAMP-dependent kinase regulatory chain family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101870326 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9P1 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/13146:LOC101878232 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFV0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872259 ^@ http://purl.uniprot.org/uniprot/A0A8C6NER3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101874385 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6F0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/13146:LOC101881107 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6P0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic ribosomal protein eL27 family.|||Endoplasmic reticulum|||Rough endoplasmic reticulum http://togogenome.org/gene/13146:LOC101873224 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101871117 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1P4 ^@ Similarity ^@ Belongs to the TAFA family. http://togogenome.org/gene/13146:LOC101867715 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869869 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the JUPITER family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101867889 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK74 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868506 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Z7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. http://togogenome.org/gene/13146:LOC106023564 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF27 ^@ Similarity ^@ Belongs to the CSN9 family. http://togogenome.org/gene/13146:LOC101878424 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVA3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CCDC93 family.|||Early endosome http://togogenome.org/gene/13146:LOC101875318 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4V0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM172 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101868655 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQ77 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.|||Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.|||Cytoplasm|||Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.|||Nucleus speckle|||Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits. http://togogenome.org/gene/13146:LOC101879483 ^@ http://purl.uniprot.org/uniprot/A0A8C6J836 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane|||cell cortex|||cytoskeleton http://togogenome.org/gene/13146:LOC101874179 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY07 ^@ Similarity ^@ Belongs to the CRK family. http://togogenome.org/gene/13146:LOC101880171 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101878302 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Membrane http://togogenome.org/gene/13146:LOC101872645 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYY4 ^@ Similarity ^@ Belongs to the BCLAF1/THRAP3 family. http://togogenome.org/gene/13146:LOC101878186 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFQ6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS8 family. http://togogenome.org/gene/13146:LOC101873919 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101878586 ^@ http://purl.uniprot.org/uniprot/A0A8C6K175 ^@ Similarity ^@ Belongs to the TMEM9 family. http://togogenome.org/gene/13146:LOC101878868 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the SPC25 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/13146:LOC101873963 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/13146:LOC101881630 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1N3 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/13146:LOC101869739 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the band 7/mec-2 family.|||Membrane http://togogenome.org/gene/13146:LOC101877680 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYV7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Apical cell membrane|||Belongs to the G-protein coupled receptor Fz/Smo family.|||Cell membrane|||Cell surface|||Cytoplasmic vesicle membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101874592 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DIM1 family.|||Nucleus|||Plays role in pre-mRNA splicing. http://togogenome.org/gene/13146:LOC101871234 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Toll-like receptor family.|||Membrane http://togogenome.org/gene/13146:LOC101881600 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RETREG family.|||Membrane http://togogenome.org/gene/13146:LOC101878923 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAB4 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/13146:LOC101872720 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIW0 ^@ Subcellular Location Annotation ^@ Golgi apparatus|||Membrane raft|||Secreted http://togogenome.org/gene/13146:LOC101872084 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXH8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/13146:LOC101878612 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU75 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Nth/MutY family.|||Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.|||Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.|||Mitochondrion|||Nucleus http://togogenome.org/gene/13146:LOC101868831 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWI3 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/13146:LOC101873354 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN68 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/13146:LOC101876099 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8V9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/13146:LOC101881501 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTJ9 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101876879 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.|||Secreted http://togogenome.org/gene/13146:LOC101869506 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR09 ^@ Similarity ^@ Belongs to the phosducin family. http://togogenome.org/gene/13146:LOC101879124 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLL4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869674 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5E1 ^@ Similarity ^@ Belongs to the gasdermin family. http://togogenome.org/gene/13146:LOC101873079 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family.|||Membrane http://togogenome.org/gene/13146:LOC101873514 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQM2 ^@ Similarity ^@ Belongs to the MIF family. http://togogenome.org/gene/13146:LOC101875558 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101872951 ^@ http://purl.uniprot.org/uniprot/A0A8C6ING5 ^@ Similarity ^@ Belongs to the cystatin family. http://togogenome.org/gene/13146:LOC101880384 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the extended synaptotagmin family.|||Cell membrane|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101880125 ^@ http://purl.uniprot.org/uniprot/A0A8C6IST6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101867979 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRI8 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101869142 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family.|||Nucleus http://togogenome.org/gene/13146:LOC101868486 ^@ http://purl.uniprot.org/uniprot/A0A8C6JID1 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL6 family. http://togogenome.org/gene/13146:LOC101871237 ^@ http://purl.uniprot.org/uniprot/A0A8C6N790 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101879798 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 10 family.|||Golgi stack membrane http://togogenome.org/gene/13146:LOC101873940 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871166 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMG3|||http://purl.uniprot.org/uniprot/A0A8C6JQE4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101871590 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQC5 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/13146:LOC101870851 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8T2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bifunctional mRNA-capping enzyme exhibiting RNA 5'-triphosphate monophosphatase activity in the N-terminal part and mRNA guanylyltransferase activity in the C-terminal part. Catalyzes the first two steps of cap formation: by removing the gamma-phosphate from the 5'-triphosphate end of nascent mRNA to yield a diphosphate end, and by transferring the GMP moiety of GTP to the 5'-diphosphate terminus of RNA via a covalent enzyme-GMP reaction intermediate.|||In the C-terminal section; belongs to the eukaryotic GTase family.|||In the N-terminal section; belongs to the non-receptor class of the protein-tyrosine phosphatase family.|||Nucleus http://togogenome.org/gene/13146:LOC101871417 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS37 ^@ Similarity ^@ Belongs to the FBPase class 1 family. http://togogenome.org/gene/13146:LOC101875281 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZG4 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101870641 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ro 60 kDa family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875391 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family.|||Membrane http://togogenome.org/gene/13146:LOC101868087 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane http://togogenome.org/gene/13146:LOC101869045 ^@ http://purl.uniprot.org/uniprot/A0A8C6K383 ^@ Similarity ^@ Belongs to the FAM193 family. http://togogenome.org/gene/13146:LOC101880150 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the IAP family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101868366 ^@ http://purl.uniprot.org/uniprot/A0A8C6K198 ^@ Similarity ^@ Belongs to the RAMP family. http://togogenome.org/gene/13146:LOC101873334 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXC2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101869316 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SNAP-25 family.|||synaptosome http://togogenome.org/gene/13146:LOC101873646 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR01 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101873403 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5J9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870268 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQH9 ^@ Activity Regulation|||Similarity ^@ Activated by threonine and tyrosine phosphorylation.|||Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.|||Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/13146:LOC101868825 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP43 family.|||cilium basal body http://togogenome.org/gene/13146:LOC101868867 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK52 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.|||Homodimer; disulfide-linked.|||Membrane http://togogenome.org/gene/13146:LOC101872637 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.|||Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875033 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLF9 ^@ Similarity|||Subunit ^@ Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.|||Heterodimer of a catalytic heavy chain and a regulatory light chain. http://togogenome.org/gene/13146:LOC101871826 ^@ http://purl.uniprot.org/uniprot/A0A8C6N919 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874709 ^@ http://purl.uniprot.org/uniprot/A0A8C6K095 ^@ Miscellaneous|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer.|||In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes. http://togogenome.org/gene/13146:LOC101881872 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKW6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101874899 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPB8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101877511 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Membrane|||Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. http://togogenome.org/gene/13146:LOC101868373 ^@ http://purl.uniprot.org/uniprot/A0A8C6K149 ^@ Function|||Similarity|||Subunit ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.|||Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.|||Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site. http://togogenome.org/gene/13146:LOC101868579 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/13146:LOC101878675 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEK3 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/13146:LOC101878978 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Y2 ^@ Function|||Subcellular Location Annotation ^@ Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.|||cytoskeleton http://togogenome.org/gene/13146:LOC101877995 ^@ http://purl.uniprot.org/uniprot/A0A8C6K564 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/13146:LOC101872387 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP04 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SDA1 family.|||Required for 60S pre-ribosomal subunits export to the cytoplasm.|||nucleolus http://togogenome.org/gene/13146:LOC101869976 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4K0 ^@ Similarity ^@ Belongs to the CTNNBIP1 family. http://togogenome.org/gene/13146:LOC101876793 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6H3 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/13146:LOC101871411 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family.|||Membrane http://togogenome.org/gene/13146:LOC101872002 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3Z0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.|||Membrane http://togogenome.org/gene/13146:LOC101874507 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101867708 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ashwin family.|||Nucleus http://togogenome.org/gene/13146:LOC101875093 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101867861 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA14 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870778 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/13146:LOC101879945 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/13146:LOC101871235 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1D9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type-B carboxylesterase/lipase family.|||Secreted http://togogenome.org/gene/13146:LOC101881299 ^@ http://purl.uniprot.org/uniprot/A0A8C6K489 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874824 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSR3 ^@ Similarity ^@ Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. http://togogenome.org/gene/13146:LOC101874530 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKM8 ^@ Similarity ^@ Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. http://togogenome.org/gene/13146:LOC101880998 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tissue factor family.|||Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.|||Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII. http://togogenome.org/gene/13146:LOC101879919 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU21 ^@ Similarity ^@ Belongs to the SLT11 family. http://togogenome.org/gene/13146:LOC101878570 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSD6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Interacts with MTUS1.|||Membrane http://togogenome.org/gene/13146:LOC101874099 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUT6 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/13146:LOC101870430 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS46 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ITM2 family.|||Membrane http://togogenome.org/gene/13146:LOC101871416 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVG0|||http://purl.uniprot.org/uniprot/A0A8C6IXG5 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101872123 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRZ7 ^@ Similarity|||Subunit ^@ Belongs to the uridine kinase family.|||Homotetramer. http://togogenome.org/gene/13146:LOC101871796 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV03 ^@ Similarity|||Subunit ^@ Belongs to the DapA family.|||Homotetramer. http://togogenome.org/gene/13146:LOC101879754 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Endosome|||Late endosome|||Membrane http://togogenome.org/gene/13146:LOC101869340 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE15 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL31 family.|||Component of the large ribosomal subunit. http://togogenome.org/gene/13146:LOC101871828 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZJ5 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/13146:LOC101876290 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISX5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycoprotein hormones subunit beta family.|||Secreted http://togogenome.org/gene/13146:LOC101877397 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the shroom family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101871342 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY08 ^@ Similarity ^@ Belongs to the NDK family. http://togogenome.org/gene/13146:LOC101870620 ^@ http://purl.uniprot.org/uniprot/A0A8C6J954 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/13146:LOC101877176 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/13146:LOC101870279 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVC8 ^@ Similarity ^@ Belongs to the ATP:guanido phosphotransferase family. http://togogenome.org/gene/13146:LOC101867789 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7L6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869592 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND10 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/13146:LOC101869196 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8Z1 ^@ Similarity ^@ Belongs to the R-spondin family. http://togogenome.org/gene/13146:LOC101873877 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6E8 ^@ Similarity ^@ Belongs to the paralemmin family. http://togogenome.org/gene/13146:LOC101872034 ^@ http://purl.uniprot.org/uniprot/A0A8C6K377 ^@ Subcellular Location Annotation ^@ centriolar satellite|||cilium membrane http://togogenome.org/gene/13146:LOC101875588 ^@ http://purl.uniprot.org/uniprot/A0A8C6JET8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MTFR1 family.|||Mitochondrion|||Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission. http://togogenome.org/gene/13146:LOC101876561 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQH5 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101870201 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ATG12 family.|||Forms a conjugate with ATG5.|||Ubiquitin-like protein involved in autophagic vesicle formation. http://togogenome.org/gene/13146:LOC101872729 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7M5 ^@ Subcellular Location Annotation ^@ cytoskeleton|||cytosol http://togogenome.org/gene/13146:LOC101873931 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQG8 ^@ Subcellular Location Annotation ^@ Membrane|||Nucleus|||autophagosome http://togogenome.org/gene/13146:LOC101878609 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.|||cytoskeleton http://togogenome.org/gene/13146:LOC101876329 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAB7 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 2 family. http://togogenome.org/gene/13146:LOC101868792 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101880491 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1D3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101875822 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCP2 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101880224 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Y3 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor Fz/Smo family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101881690 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101878696 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZM8 ^@ Domain|||Function|||Similarity ^@ Belongs to the SINA (Seven in absentia) family.|||E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.|||The RING-type zinc finger domain is essential for ubiquitin ligase activity.|||The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family. http://togogenome.org/gene/13146:LOC101873278 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE17 ^@ Subcellular Location Annotation ^@ Membrane|||dendrite http://togogenome.org/gene/13146:LOC101868528 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1K1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the hydrogen channel family.|||Homodimer.|||Membrane http://togogenome.org/gene/13146:LOC101868169 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXM4 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874844 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bestrophin family.|||Cell membrane|||Forms chloride channels.|||Membrane http://togogenome.org/gene/13146:LOC101876908 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the vasculin family.|||Nucleus http://togogenome.org/gene/13146:LOC101881560 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEE1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SYF2 family.|||Involved in pre-mRNA splicing.|||May be part of a spliceosome complex.|||Nucleus http://togogenome.org/gene/13146:LOC101873507 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFN6 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/13146:LOC101870812 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUU3 ^@ Similarity ^@ Belongs to the peptidase C12 family. http://togogenome.org/gene/13146:LOC101881561 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG26 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101869483 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWU8 ^@ Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family. http://togogenome.org/gene/13146:LOC101874701 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone H1/H5 family.|||Nucleus http://togogenome.org/gene/13146:LOC101871550 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTS2 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/13146:LOC101877004 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVZ4 ^@ Similarity ^@ Belongs to the eukaryotic initiation factor 4E family. http://togogenome.org/gene/13146:LOC101876698 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3L5 ^@ Function|||Similarity ^@ Belongs to the VPS35 family.|||Plays a role in vesicular protein sorting. http://togogenome.org/gene/13146:LOC101879927 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PER33/POM33 family.|||Membrane http://togogenome.org/gene/13146:LOC101872958 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0T9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VMA21 family.|||COPII-coated vesicle membrane|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum. http://togogenome.org/gene/13146:LOC101874453 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJN6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101874916 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPZ4 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/13146:LOC101872509 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL56 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.|||May play a role in motor coordination and exploratory behavior. http://togogenome.org/gene/13146:LOC101870447 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8T5 ^@ Similarity ^@ Belongs to the small GTPase superfamily. RGK family. http://togogenome.org/gene/13146:LOC101877115 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE32 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. http://togogenome.org/gene/13146:LOC101875999 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVC4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101879336 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1C9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101872329 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6F0 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101874990 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4M1 ^@ Similarity ^@ Belongs to the NXPE family. http://togogenome.org/gene/13146:LOC101873312 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT01 ^@ Function|||Similarity ^@ Belongs to the queuosine salvage protein family.|||Involved in salvaging queuosine. http://togogenome.org/gene/13146:LOC101869612 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILP0 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily. http://togogenome.org/gene/13146:LOC101878141 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVD3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101869399 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ku80 family.|||Nucleus|||Single-stranded DNA-dependent ATP-dependent helicase. http://togogenome.org/gene/13146:LOC101872009 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872069 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ORC2 family.|||Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.|||Component of the origin recognition complex (ORC).|||Nucleus http://togogenome.org/gene/13146:LOC101876782 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R1 ^@ Similarity ^@ Belongs to the mab-21 family. http://togogenome.org/gene/13146:LOC101868214 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted http://togogenome.org/gene/13146:LOC101880718 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVL8 ^@ Similarity ^@ Belongs to the sorting nexin family. http://togogenome.org/gene/13146:LOC101869448 ^@ http://purl.uniprot.org/uniprot/A0A8C6N944 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CAF1 family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101874692 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9D1 ^@ Similarity ^@ Belongs to the SLITRK family. http://togogenome.org/gene/13146:LOC101874518 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7F0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101877167 ^@ http://purl.uniprot.org/uniprot/A0A8C6INH7 ^@ Similarity ^@ Belongs to the FAM114 family. http://togogenome.org/gene/13146:LOC101876184 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUP3 ^@ Similarity ^@ Belongs to the FAM110 family. http://togogenome.org/gene/13146:LOC101881777 ^@ http://purl.uniprot.org/uniprot/A0A8C6N866 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101877818 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874159 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CEP19 family.|||centriole|||cilium basal body|||spindle pole http://togogenome.org/gene/13146:LOC101873961 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0B8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101874589 ^@ http://purl.uniprot.org/uniprot/A0A8C6N607 ^@ Similarity ^@ Belongs to the peptidase C13 family. http://togogenome.org/gene/13146:LOC101873024 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDR6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family. http://togogenome.org/gene/13146:LOC101876166 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW17 ^@ Subcellular Location Annotation ^@ Synapse|||axon|||dendritic spine http://togogenome.org/gene/13146:LOC101881083 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101877716 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT38 ^@ Similarity ^@ Belongs to the RPAP1 family. http://togogenome.org/gene/13146:LOC101870823 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein arginine deiminase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101881430 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCY9 ^@ Similarity ^@ Belongs to the amidase family. http://togogenome.org/gene/13146:LOC101868016 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ETS family.|||Nucleus http://togogenome.org/gene/13146:LOC101872462 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101869091 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101873170 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DENND6 family.|||Endosome|||Recycling endosome http://togogenome.org/gene/13146:LOC101874763 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTJ4 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101874596 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2K1|||http://purl.uniprot.org/uniprot/A0A8C6N8Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the galanin family.|||Secreted http://togogenome.org/gene/13146:LOC101880817 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RRM RBM47 family.|||Nucleus http://togogenome.org/gene/13146:LOC101878163 ^@ http://purl.uniprot.org/uniprot/A0A8C6K7X6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. http://togogenome.org/gene/13146:LOC101872848 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3C9 ^@ Similarity|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer; disulfide-linked. http://togogenome.org/gene/13146:LOC101870770 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQW0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane|||Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport. http://togogenome.org/gene/13146:LOC101870643 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/13146:LOC101874136 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA43 RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/13146:LOC101880156 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7M5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879745 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1E7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/13146:LOC101867988 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the synembryn family.|||Cytoplasm|||Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.|||Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma. http://togogenome.org/gene/13146:LOC101879075 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHR6 ^@ Similarity ^@ Belongs to the RELT family. http://togogenome.org/gene/13146:LOC101877112 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN75 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the neuregulin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101879367 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWN3 ^@ Similarity ^@ Belongs to the DCK/DGK family. http://togogenome.org/gene/13146:LOC101877022 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0J3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101868420 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Mediator complex subunit 13 family.|||Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Component of the Mediator complex.|||Nucleus http://togogenome.org/gene/13146:LOC101872404 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXW5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101873516 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1E4|||http://purl.uniprot.org/uniprot/A0A8C6K2F3 ^@ Caution|||Subcellular Location Annotation ^@ Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101879062 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/13146:LOC101876777 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101871972 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZF4 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell junction|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871341 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQT1 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/13146:LOC101876785 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ41 ^@ Function|||Similarity ^@ Belongs to the 5'-AMP-activated protein kinase beta subunit family.|||Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3). http://togogenome.org/gene/13146:LOC101871510 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876637 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3J0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101874883 ^@ http://purl.uniprot.org/uniprot/A0A8C6JB27 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDK/BCKDK protein kinase family.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101872195 ^@ http://purl.uniprot.org/uniprot/A0A8C6J507 ^@ Similarity ^@ Belongs to the TAPR1 family. http://togogenome.org/gene/13146:LOC101870184 ^@ http://purl.uniprot.org/uniprot/A0A8C6INU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protein sulfotransferase family.|||Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.|||Golgi apparatus membrane http://togogenome.org/gene/13146:LOC101878319 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NGG1 family.|||Nucleus http://togogenome.org/gene/13146:LOC101876624 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF02 ^@ Function|||Similarity ^@ Belongs to the globin family.|||Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. http://togogenome.org/gene/13146:LOC101870181 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101873426 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUR7 ^@ Similarity ^@ Belongs to the MIP18 family. http://togogenome.org/gene/13146:LOC101875371 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ04 ^@ Similarity ^@ Belongs to the BRINP family. http://togogenome.org/gene/13146:LOC101871664 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGK2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NodC/HAS family.|||Endoplasmic reticulum membrane|||Lysosome|||Membrane http://togogenome.org/gene/13146:LOC101868408 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF07 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the intercrine alpha (chemokine CxC) family.|||Homodimer.|||Secreted http://togogenome.org/gene/13146:LOC101877058 ^@ http://purl.uniprot.org/uniprot/A0A8C6INB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Melanosome|||Membrane|||SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.|||cis-Golgi network membrane|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101870885 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8D3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. http://togogenome.org/gene/13146:LOC101868359 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZL1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ephrin family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101880362 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQT4 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101873083 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8L1 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase family.|||Homodimer. http://togogenome.org/gene/13146:LOC101879563 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXK5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL14 family. http://togogenome.org/gene/13146:LOC101878420 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6H5 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Component of the 40S small ribosomal subunit. http://togogenome.org/gene/13146:LOC101875551 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY04|||http://purl.uniprot.org/uniprot/A0A8C6K0Y3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the InsP3 receptor family.|||Endoplasmic reticulum membrane|||Homotetramer.|||Membrane|||Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.|||The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region. http://togogenome.org/gene/13146:LOC101876347 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILS4 ^@ Similarity ^@ Belongs to the SEC6 family. http://togogenome.org/gene/13146:LOC101875675 ^@ http://purl.uniprot.org/uniprot/A0A8C6K018 ^@ Similarity ^@ Belongs to the RHPN family. http://togogenome.org/gene/13146:LOC101874470 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7B0 ^@ Similarity ^@ Belongs to the TFIIB family. http://togogenome.org/gene/13146:LOC101872927 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUY2 ^@ Similarity ^@ Belongs to the activator 1 small subunits family. http://togogenome.org/gene/13146:LOC101881811 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLK4 ^@ Similarity ^@ Belongs to the rtf2 family. http://togogenome.org/gene/13146:LOC101869720 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8V8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homo- and heterotetramers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101874966 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2R3 ^@ Similarity ^@ Belongs to the aldo/keto reductase family. http://togogenome.org/gene/13146:LOC101873571 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ2 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101876648 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEJ0 ^@ Similarity ^@ Belongs to the dynein light chain Tctex-type family. http://togogenome.org/gene/13146:LOC101878121 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW79|||http://purl.uniprot.org/uniprot/A0A8C6JXY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101870582 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the POU transcription factor family. Class-2 subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101873644 ^@ http://purl.uniprot.org/uniprot/A0A8C6J127 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC2 subfamily.|||Chromosome|||Nucleus http://togogenome.org/gene/13146:LOC101871498 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101868473 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101880638 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM3 family.|||Secreted http://togogenome.org/gene/13146:LOC101880509 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU20 ^@ Similarity ^@ Belongs to the perilipin family. http://togogenome.org/gene/13146:LOC101876039 ^@ http://purl.uniprot.org/uniprot/A0A8C6K078 ^@ Similarity ^@ Belongs to the cyclin family. http://togogenome.org/gene/13146:LOC101870598 ^@ http://purl.uniprot.org/uniprot/A0A8C6JU22 ^@ Similarity ^@ Belongs to the chondromodulin-1 family. http://togogenome.org/gene/13146:LOC101868670 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the integrin alpha chain family.|||Membrane http://togogenome.org/gene/13146:LOC101876788 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIU5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101881703 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Mediator complex subunit 30 family.|||Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.|||Nucleus http://togogenome.org/gene/13146:LOC101873130 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0A7 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily. http://togogenome.org/gene/13146:LOC101875237 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBA4 ^@ Similarity ^@ Belongs to the peptidase C14A family. http://togogenome.org/gene/13146:LOC101875229 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GINS3/PSF3 family.|||Chromosome|||Component of the GINS complex.|||Nucleus|||The GINS complex plays an essential role in the initiation of DNA replication. http://togogenome.org/gene/13146:LOC101880264 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUB2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.|||Nucleus http://togogenome.org/gene/13146:LOC101868206 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101875600 ^@ http://purl.uniprot.org/uniprot/A0A8C6IN76 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.|||Catalyzes the hydrolysis of ATP coupled with the transport of calcium.|||Golgi stack membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. Homodimer.|||trans-Golgi network membrane http://togogenome.org/gene/13146:LOC101879527 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.|||Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.|||Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine. http://togogenome.org/gene/13146:LOC101879797 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSE3 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. http://togogenome.org/gene/13146:LOC101876137 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLZ1|||http://purl.uniprot.org/uniprot/A0A8C6JR39 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/13146:LOC101878238 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCT5 ^@ Subcellular Location Annotation|||Subunit ^@ Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.|||Secreted http://togogenome.org/gene/13146:LOC101879026 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZS9 ^@ Similarity ^@ Belongs to the WFIKKN family. http://togogenome.org/gene/13146:LOC101872499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HMGN family.|||Nucleus http://togogenome.org/gene/13146:LOC101871010 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the P33MONOX family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101878418 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUY7 ^@ Similarity ^@ Belongs to the yippee family. http://togogenome.org/gene/13146:LOC101877936 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4D5 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/13146:LOC101878164 ^@ http://purl.uniprot.org/uniprot/A0A8C6K558 ^@ Similarity ^@ Belongs to the MDFI family. http://togogenome.org/gene/13146:LOC101876719 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101874582 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHC9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101869893 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PSMG2 family.|||Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.|||Forms a heterodimer with PSMG1. http://togogenome.org/gene/13146:LOC101869201 ^@ http://purl.uniprot.org/uniprot/A0A8C6K5Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.|||Cytoplasm|||Nucleus|||Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'. http://togogenome.org/gene/13146:LOC101880033 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF17 ^@ Similarity ^@ Belongs to the uridine kinase family. http://togogenome.org/gene/13146:LOC101868037 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEX5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871949 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYA1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871507 ^@ http://purl.uniprot.org/uniprot/A0A8C6K548 ^@ Activity Regulation|||Similarity|||Subcellular Location Annotation ^@ Activated by DAG and phorbol esters.|||Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.|||Cytoplasm|||Membrane http://togogenome.org/gene/13146:LOC101879574 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFA12 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101868900 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM200 family.|||Membrane http://togogenome.org/gene/13146:LOC101872410 ^@ http://purl.uniprot.org/uniprot/A0A8C6IL49 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101870454 ^@ http://purl.uniprot.org/uniprot/A0A8C6JA02 ^@ Similarity ^@ Belongs to the poly(ADP-ribose) glycohydrolase family. http://togogenome.org/gene/13146:LOC101870722 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the COX16 family.|||Membrane http://togogenome.org/gene/13146:LOC101869781 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPJ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglutaminase-like superfamily. PNGase family.|||Cytoplasm|||Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins. http://togogenome.org/gene/13146:LOC101868040 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9R7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.|||Cytoplasm|||Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.|||Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. http://togogenome.org/gene/13146:LOC101880659 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the alpha-carbonic anhydrase family.|||Cytoplasm|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/13146:LOC101872301 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1F9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosyl-DNA phosphodiesterase family.|||Nucleus http://togogenome.org/gene/13146:LOC101873558 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7G9 ^@ Similarity ^@ Belongs to the PPP phosphatase family. http://togogenome.org/gene/13146:LOC101875699 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAZ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MDM2/MDM4 family.|||Cytoplasm|||nucleolus|||nucleoplasm http://togogenome.org/gene/13146:LOC101871973 ^@ http://purl.uniprot.org/uniprot/A0A8C6J071|||http://purl.uniprot.org/uniprot/A0A8C6J0H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMAUG family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101872759 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101874880 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQX0 ^@ Similarity ^@ Belongs to the syntaxin family. http://togogenome.org/gene/13146:LOC101868715 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PDGF/VEGF growth factor family.|||Secreted http://togogenome.org/gene/13146:PRL ^@ http://purl.uniprot.org/uniprot/A8CGJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the somatotropin/prolactin family.|||Secreted http://togogenome.org/gene/13146:LOC101879386 ^@ http://purl.uniprot.org/uniprot/A0A8C6INP4 ^@ Similarity ^@ Belongs to the ANP32 family. http://togogenome.org/gene/13146:LOC101875597 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane http://togogenome.org/gene/13146:LOC101879997 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZL2 ^@ Subcellular Location Annotation|||Subunit ^@ Cell membrane|||Cytoplasmic vesicle membrane|||Interacts with ARF6.|||Membrane|||Presynapse|||Synapse http://togogenome.org/gene/13146:LOC101867880 ^@ http://purl.uniprot.org/uniprot/A0A8C6JES6 ^@ Similarity ^@ Belongs to the pyridoxine kinase family. http://togogenome.org/gene/13146:LOC101881315 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ61 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the insulin family.|||Secreted http://togogenome.org/gene/13146:LOC101873248 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWI7 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/13146:LOC101879714 ^@ http://purl.uniprot.org/uniprot/A0A8C6IW29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/13146:LOC101878626 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXD7 ^@ Similarity ^@ Belongs to the SMC family. RAD50 subfamily. http://togogenome.org/gene/13146:LOC101870131 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLS9 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101872024 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0602 family.|||centrosome http://togogenome.org/gene/13146:LOC101881929 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2I4 ^@ Similarity ^@ Belongs to the ubinuclein family. http://togogenome.org/gene/13146:LOC101869532 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYRI family.|||Membrane http://togogenome.org/gene/13146:LOC101880837 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF66 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101872018 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8B1 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX41 subfamily. http://togogenome.org/gene/13146:LOC101867724 ^@ http://purl.uniprot.org/uniprot/A0A8C6INY9 ^@ Similarity ^@ Belongs to the R-spondin family. http://togogenome.org/gene/13146:LOC101877084 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSP5 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/13146:LOC101879205 ^@ http://purl.uniprot.org/uniprot/A0A8C6J935 ^@ Similarity ^@ Belongs to the TTC39 family. http://togogenome.org/gene/13146:LOC101877951 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXE4 ^@ Similarity ^@ Belongs to the Bcl-2 family. http://togogenome.org/gene/13146:LOC101871051 ^@ http://purl.uniprot.org/uniprot/A0A8C6K068 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/13146:LOC101881267 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ45 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101867647 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH45 ^@ Similarity ^@ Belongs to the ubiquitin-conjugating enzyme family. http://togogenome.org/gene/13146:LOC101870917 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3W0 ^@ Caution|||Similarity ^@ Belongs to the thrombospondin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101878702 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the patched family.|||Membrane http://togogenome.org/gene/13146:LOC101869249 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the neurochondrin family.|||Postsynapse http://togogenome.org/gene/13146:LOC101870904 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVQ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallophosphoesterase superfamily. MPPE1 family.|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Membrane|||Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.|||cis-Golgi network membrane http://togogenome.org/gene/13146:LOC101870584 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYB3 ^@ Similarity ^@ Belongs to the VPS8 family. http://togogenome.org/gene/13146:LOC101881536 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3N1 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101880873 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK61 ^@ Caution|||Similarity ^@ Belongs to the secreted frizzled-related protein (sFRP) family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101870372 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBT3 ^@ Similarity ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. http://togogenome.org/gene/13146:LOC101872248 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWT1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101875201 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101868433 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2Y4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.|||Homodimer; disulfide-linked.|||Membrane http://togogenome.org/gene/13146:LOC101872405 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISJ4 ^@ Subcellular Location Annotation ^@ extracellular matrix http://togogenome.org/gene/13146:LOC101872384 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQE3 ^@ Similarity ^@ Belongs to the inositol phosphokinase (IPK) family. http://togogenome.org/gene/13146:LOC101872798 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE79 ^@ Similarity ^@ Belongs to the SGT family. http://togogenome.org/gene/13146:LOC101875937 ^@ http://purl.uniprot.org/uniprot/A0A8C6J459 ^@ Subcellular Location Annotation ^@ cytoskeleton http://togogenome.org/gene/13146:LOC101880194 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE43 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Ran family.|||GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.|||Nucleus http://togogenome.org/gene/13146:LOC101879823 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHQ1 ^@ Similarity ^@ Belongs to the nucleosome assembly protein (NAP) family. http://togogenome.org/gene/13146:LOC101875532 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8L8 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/13146:LOC101879226 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVD2 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster per subunit.|||Membrane|||Mitochondrion inner membrane|||The Rieske protein is a high potential 2Fe-2S protein. http://togogenome.org/gene/13146:LOC101879007 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYD0 ^@ Similarity ^@ Belongs to the CDR2 family. http://togogenome.org/gene/13146:LOC101880647 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY32 ^@ Similarity ^@ Belongs to the OSBP family. http://togogenome.org/gene/13146:LOC101876410 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB27 ^@ Similarity ^@ Belongs to the biotin--protein ligase family. http://togogenome.org/gene/13146:LOC101878831 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872027 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101867819 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A1 family.|||Lysosome http://togogenome.org/gene/13146:LOC101877316 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPC1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880604 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP61 ^@ Similarity ^@ Belongs to the PPase family. http://togogenome.org/gene/13146:LOC101880575 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBI1 ^@ Caution|||Cofactor|||Subcellular Location Annotation ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||extracellular matrix http://togogenome.org/gene/13146:LOC101872503 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZ76|||http://purl.uniprot.org/uniprot/A0A8C6K0X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.|||Cell membrane|||Early endosome membrane|||Endosome membrane|||Late endosome membrane|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101877569 ^@ http://purl.uniprot.org/uniprot/A0A8C6J790 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OCIAD1 family.|||Endosome|||Interacts with STAT3.|||Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.|||The OCIA domain is necessary and sufficient for endosomal localization. http://togogenome.org/gene/13146:LOC101879584 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND69 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/13146:LOC101880869 ^@ http://purl.uniprot.org/uniprot/A0A8C6J916 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/13146:LOC101867699 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chondroitin N-acetylgalactosaminyltransferase family.|||Golgi stack membrane|||Membrane http://togogenome.org/gene/13146:LOC101878504 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLY2 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. http://togogenome.org/gene/13146:LOC101878435 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITQ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mitochondrion-specific ribosomal protein mL41 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101880482 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0F8|||http://purl.uniprot.org/uniprot/A0A8C6K5H9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101871916 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVU5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2B family.|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101874733 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the VPS11 family.|||Cytoplasmic vesicle|||Early endosome|||Late endosome membrane|||Lysosome membrane|||Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.|||autophagosome|||clathrin-coated vesicle http://togogenome.org/gene/13146:LOC101878414 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Q0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/13146:LOC101880029 ^@ http://purl.uniprot.org/uniprot/A0A8C6ND66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101870141 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 31 family.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101878423 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAA3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily. http://togogenome.org/gene/13146:LOC101878506 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sorting nexin family.|||Cytoplasmic vesicle membrane http://togogenome.org/gene/13146:LOC101879244 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGC1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. http://togogenome.org/gene/13146:LOC101867826 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ZRANB2 family.|||May interfere with constitutive 5'-splice site selection.|||Nucleus http://togogenome.org/gene/13146:LOC101879944 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the paired homeobox family. Bicoid subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101874204 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM47 family.|||Membrane http://togogenome.org/gene/13146:LOC101874421 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZA0 ^@ Function|||Subcellular Location Annotation ^@ Cadherins are calcium-dependent cell adhesion proteins.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101880997 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF67 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101875550 ^@ http://purl.uniprot.org/uniprot/A0A8C6NC60 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/13146:LOC101872513 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZS5 ^@ Similarity ^@ Belongs to the CDPF1 family. http://togogenome.org/gene/13146:LOC101877353 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUR9 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101871369 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class V-like SAM-binding methyltransferase superfamily.|||Cytoplasm|||Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.|||Nucleus|||Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions. http://togogenome.org/gene/13146:LOC101873372 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta-catenin family.|||Belongs to the eutherian X-chromosome-specific Armcx family.|||Membrane|||Vacuole membrane http://togogenome.org/gene/13146:LOC101868811 ^@ http://purl.uniprot.org/uniprot/A0A8C6JR88 ^@ Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Plays an important role in the elongation step of protein synthesis. http://togogenome.org/gene/13146:LOC101875905 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3T4 ^@ Similarity ^@ Belongs to the alpha-carbonic anhydrase family. http://togogenome.org/gene/13146:LOC101869276 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRT6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the mitochondrial carrier (TC 2.A.29) family.|||Catalyzes the exchange of ADP and ATP across the membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Monomer. http://togogenome.org/gene/13146:LOC101870934 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPH3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.|||Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.|||Mitochondrion http://togogenome.org/gene/13146:LOC101881693 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXM5 ^@ Similarity ^@ Belongs to the ANKLE2 family. http://togogenome.org/gene/13146:LOC101876062 ^@ http://purl.uniprot.org/uniprot/A0A8C6K338 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||Endosome membrane|||Late endosome membrane|||Lysosome membrane http://togogenome.org/gene/13146:LOC101881357 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101874026 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXN7 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/13146:LOC101873833 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5S9 ^@ Similarity ^@ Belongs to the PRORSD1 family. http://togogenome.org/gene/13146:LOC101871745 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWU9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101873615 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCD8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the POMC family.|||Endogenous opiate.|||Secreted|||Stimulates the adrenal glands to release cortisol. http://togogenome.org/gene/13146:LOC101868651 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the unc-93 family.|||Membrane http://togogenome.org/gene/13146:LOC101870764 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQB9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101879476 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHK5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101876655 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJ64 ^@ Similarity ^@ Belongs to the FAM167 (SEC) family. http://togogenome.org/gene/13146:LOC101877209 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8Q1 ^@ Similarity ^@ Belongs to the angiomotin family. http://togogenome.org/gene/13146:LOC101870529 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITJ8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the cysteine dioxygenase family.|||Binds 1 Fe cation per subunit.|||Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen. http://togogenome.org/gene/13146:LOC101879904 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGB7 ^@ Similarity ^@ Belongs to the GDA1/CD39 NTPase family. http://togogenome.org/gene/13146:LOC101878177 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9B4 ^@ Similarity ^@ Belongs to the NFX1 family. http://togogenome.org/gene/13146:LOC101881387 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ELL/occludin family.|||Nucleus http://togogenome.org/gene/13146:LOC101875454 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6J9 ^@ Similarity ^@ Belongs to the SNF2/RAD54 helicase family. http://togogenome.org/gene/13146:LOC101879408 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XK family.|||Membrane http://togogenome.org/gene/13146:LOC101877002 ^@ http://purl.uniprot.org/uniprot/A0A8C6K164 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M16 family.|||Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101868499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEL2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878445 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6V3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TCP-1 chaperonin family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101878191 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the C19orf12 family.|||Mitochondrion membrane http://togogenome.org/gene/13146:LOC101877328 ^@ http://purl.uniprot.org/uniprot/A0A8C6INI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. http://togogenome.org/gene/13146:LOC101881821 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lin-7 family.|||Cell junction|||Cell membrane|||Membrane|||Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. http://togogenome.org/gene/13146:LOC101869030 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nudE family.|||centrosome|||spindle http://togogenome.org/gene/13146:LOC101868352 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CITED family.|||Nucleus http://togogenome.org/gene/13146:LOC101879284 ^@ http://purl.uniprot.org/uniprot/A0A8C6K303 ^@ Subcellular Location Annotation ^@ Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101876501 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU81 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MESD family.|||Endoplasmic reticulum http://togogenome.org/gene/13146:LOC101868048 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHM4 ^@ Subcellular Location Annotation ^@ Cell membrane|||invadopodium membrane|||lamellipodium membrane http://togogenome.org/gene/13146:LOC101878270 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUM9 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/13146:LOC101881001 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6J3 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/13146:LOC101869736 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH71 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101868093 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCZ0|||http://purl.uniprot.org/uniprot/A0A8C6JEU4|||http://purl.uniprot.org/uniprot/A0A8C6JGQ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.|||Cell membrane|||Membrane|||Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. http://togogenome.org/gene/13146:LOC101875571 ^@ http://purl.uniprot.org/uniprot/A0A8C6JSA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XRCC4-XLF family. XLF subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101880784 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyadenylate-binding protein type-1 family.|||Binds the poly(A) tail of mRNA.|||Cytoplasm http://togogenome.org/gene/13146:LOC101872885 ^@ http://purl.uniprot.org/uniprot/A0A8C6J309 ^@ Similarity ^@ Belongs to the actin family. ARP6 subfamily. http://togogenome.org/gene/13146:LOC101870841 ^@ http://purl.uniprot.org/uniprot/A0A8C6J540 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.|||Membrane|||Mitochondrion outer membrane http://togogenome.org/gene/13146:LOC101878363 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR65 ^@ Similarity ^@ Belongs to the TMEM106 family. http://togogenome.org/gene/13146:LOC101867996 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY60 ^@ Function|||Similarity ^@ Belongs to the WD repeat DCAF10 family.|||May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. http://togogenome.org/gene/13146:LOC101877154 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDD1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase F subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101868658 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJD8 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/13146:LOC101872424 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS18 ^@ Similarity ^@ Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily. http://togogenome.org/gene/13146:LOC101880168 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNE2 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acid sphingomyelinase family.|||Binds 2 Zn(2+) per subunit.|||Secreted http://togogenome.org/gene/13146:LOC101881193 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUM6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the VPS36 family.|||Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.|||Component of the endosomal sorting complex required for transport II (ESCRT-II).|||Cytoplasm|||Endosome http://togogenome.org/gene/13146:LOC101872941 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDT8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the F-actin-capping protein alpha subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit. http://togogenome.org/gene/13146:LOC101880929 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4I4 ^@ Function ^@ The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/13146:LOC101874932 ^@ http://purl.uniprot.org/uniprot/A0A8C6N611 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromogranin/secretogranin protein family.|||Secreted http://togogenome.org/gene/13146:LOC101868507 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the translin family.|||DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.|||Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.|||Nucleus|||Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring. http://togogenome.org/gene/13146:LOC101873368 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW34 ^@ Function ^@ Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. http://togogenome.org/gene/13146:LOC101871672 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0A2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TFIIA subunit 2 family.|||Nucleus|||TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. http://togogenome.org/gene/13146:LOC101868301 ^@ http://purl.uniprot.org/uniprot/A0A8C6IP53 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NADP-dependent oxidoreductase L4BD family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/13146:LOC101880775 ^@ http://purl.uniprot.org/uniprot/A0A8C6J545 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tektin family.|||flagellum http://togogenome.org/gene/13146:LOC101870781 ^@ http://purl.uniprot.org/uniprot/A0A8C6NET9 ^@ Similarity ^@ Belongs to the NCF2/NOXA1 family. http://togogenome.org/gene/13146:LOC101869269 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101875751 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMP5 ^@ Similarity ^@ Belongs to the MAK16 family. http://togogenome.org/gene/13146:LOC101875738 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC32 ^@ Similarity ^@ Belongs to the dynein intermediate chain family. http://togogenome.org/gene/13146:LOC101871787 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7E5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase C14A family.|||Cytoplasm|||Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.|||Nucleus http://togogenome.org/gene/13146:LOC101871748 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZR7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101881287 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYQ0 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/13146:LOC101880644 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the proteasome subunit S2 family.|||Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.|||Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).|||Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. http://togogenome.org/gene/13146:LOC101880041 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXV4 ^@ Similarity ^@ Belongs to the CRISP family. http://togogenome.org/gene/13146:LOC101873766 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLT5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sestrin family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101869454 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEZ1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c family.|||Binds 1 heme group per subunit.|||Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.|||Mitochondrion intermembrane space http://togogenome.org/gene/13146:LOC101879305 ^@ http://purl.uniprot.org/uniprot/A0A8C6J980 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PIGU family.|||Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101873524 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMJ6 ^@ Function|||Similarity ^@ Belongs to the RutC family.|||Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase. http://togogenome.org/gene/13146:LOC101868450 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the derlin family.|||Endoplasmic reticulum membrane|||Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.|||Membrane http://togogenome.org/gene/13146:LOC101879982 ^@ http://purl.uniprot.org/uniprot/A0A8C6J117 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heparin-binding growth factors family.|||Cytoplasm|||Nucleus|||Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.|||Secreted|||cell cortex|||cytosol http://togogenome.org/gene/13146:LOC101869109 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3I6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the XPF family.|||Nucleus http://togogenome.org/gene/13146:LOC101881833 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUZ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.|||Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).|||Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.|||Membrane http://togogenome.org/gene/13146:LOC101872567 ^@ http://purl.uniprot.org/uniprot/A0A8C6IS28 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/13146:LOC101875112 ^@ http://purl.uniprot.org/uniprot/A0A8C6J289 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/13146:LOC101869832 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITW7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101871298 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the akirin family.|||Nucleus http://togogenome.org/gene/13146:LOC101871747 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101879352 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CYSTM1 family.|||Membrane http://togogenome.org/gene/13146:LOC101869325 ^@ http://purl.uniprot.org/uniprot/A0A8C6K696 ^@ Similarity ^@ Belongs to the ADP-ribosylglycohydrolase family. http://togogenome.org/gene/13146:LOC101874301 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRU6 ^@ Similarity ^@ Belongs to the LRRC42 family. http://togogenome.org/gene/13146:LOC101867694 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP21 ^@ Subcellular Location Annotation ^@ Early endosome|||Endosome http://togogenome.org/gene/13146:LOC101873585 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIJ8 ^@ Similarity ^@ Belongs to the fl(2)d family. http://togogenome.org/gene/13146:LOC101875368 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Caudal homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101876796 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0V6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine gamma family.|||Secreted http://togogenome.org/gene/13146:LOC101870809 ^@ http://purl.uniprot.org/uniprot/A0A8C6K724 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101872579 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILB5 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.|||Nucleus http://togogenome.org/gene/13146:LOC101873103 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM60 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the kynurenine formamidase family.|||Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.|||Homodimer.|||Nucleus|||The main chain amide nitrogen atoms of the second glycine and its adjacent residue in the HGGXW motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.|||cytosol http://togogenome.org/gene/13146:LOC101869818 ^@ http://purl.uniprot.org/uniprot/A0A8C6K6R0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily. http://togogenome.org/gene/13146:LOC101869496 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFC1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the protein kinase superfamily. ADCK protein kinase family.|||Secreted http://togogenome.org/gene/13146:LOC101877370 ^@ http://purl.uniprot.org/uniprot/A0A8C6K482 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CRF-binding protein family.|||Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.|||Secreted http://togogenome.org/gene/13146:LOC101872831 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDP3 ^@ Similarity ^@ Belongs to the LanC-like protein family. http://togogenome.org/gene/13146:LOC101874263 ^@ http://purl.uniprot.org/uniprot/A0A8C6IV22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/13146:LOC101875570 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFS6 subunit family.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101877836 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane|||The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. http://togogenome.org/gene/13146:LOC101881456 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE73 ^@ Similarity ^@ Belongs to the peptidase S28 family. http://togogenome.org/gene/13146:LOC101880276 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TDE1 family.|||Membrane http://togogenome.org/gene/13146:LOC101875455 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874506 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the squalene monooxygenase family.|||Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101879664 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Q9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/13146:LOC101881734 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGB8 ^@ Similarity ^@ Belongs to the adaptor complexes medium subunit family. http://togogenome.org/gene/13146:LOC101870622 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Tim17/Tim22/Tim23 family.|||Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.|||Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101877015 ^@ http://purl.uniprot.org/uniprot/A0A8C6J495 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/13146:LOC101878043 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNB7 ^@ Similarity|||Subunit ^@ Belongs to the ADPRibase-Mn family.|||Monomer. http://togogenome.org/gene/13146:LOC101873786 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway. http://togogenome.org/gene/13146:LOC101874703 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.|||Cell membrane|||Membrane|||Perikaryon http://togogenome.org/gene/13146:LOC101878691 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/13146:LOC101868360 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876897 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0Q9 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101877495 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4G2 ^@ Subcellular Location Annotation ^@ Membrane|||Secreted|||secretory vesicle membrane http://togogenome.org/gene/13146:LOC101872245 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK39 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101878582 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7U9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LBH family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101872078 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FRG1 family.|||Cajal body|||nucleolus http://togogenome.org/gene/13146:LOC101870377 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8K5 ^@ Similarity ^@ Belongs to the KDELC family. http://togogenome.org/gene/13146:LOC101874088 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872176 ^@ http://purl.uniprot.org/uniprot/A0A8C6JQF8|||http://purl.uniprot.org/uniprot/A0A8C6NE91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the F-actin-capping protein beta subunit family.|||F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.|||Heterodimer of an alpha and a beta subunit.|||cytoskeleton http://togogenome.org/gene/13146:LOC101874312 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZP7 ^@ Similarity ^@ Belongs to the serpin family. http://togogenome.org/gene/13146:LOC101870661 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAY2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/13146:LOC101879495 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the splicing factor SR family.|||Nucleus speckle http://togogenome.org/gene/13146:LOC101880995 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101872039 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/13146:LOC101871075 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2B4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetyltransferase family. NAA60 subfamily.|||Golgi apparatus membrane http://togogenome.org/gene/13146:LOC101870718 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6Z2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GPN-loop GTPase family.|||Binds to RNA polymerase II.|||Cytoplasm|||Nucleus|||Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. http://togogenome.org/gene/13146:LOC101868006 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tyrosinase family.|||Melanosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101881650 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1L5 ^@ Similarity ^@ Belongs to the FAM10 family. http://togogenome.org/gene/13146:LOC101874461 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTD0 ^@ Similarity ^@ Belongs to the 14-3-3 family. http://togogenome.org/gene/13146:LOC101878347 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DAN family.|||Secreted http://togogenome.org/gene/13146:LOC101868891 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGX1 ^@ Subcellular Location Annotation ^@ cilium axoneme http://togogenome.org/gene/13146:LOC101869874 ^@ http://purl.uniprot.org/uniprot/A0A8C6JZH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ORM family.|||Endoplasmic reticulum membrane|||Membrane|||Negative regulator of sphingolipid synthesis. http://togogenome.org/gene/13146:LOC101878961 ^@ http://purl.uniprot.org/uniprot/A0A8C6INP9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prostaglandin G/H synthase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Endoplasmic reticulum membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Microsome membrane http://togogenome.org/gene/13146:LOC101875422 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874108 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7D4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873143 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101869349 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6B0 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. LDH family. http://togogenome.org/gene/13146:LOC101881223 ^@ http://purl.uniprot.org/uniprot/A0A8C6IMR9 ^@ Similarity ^@ Belongs to the SH3BGR family. http://togogenome.org/gene/13146:LOC101872192 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAE1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101875379 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4I6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101871495 ^@ http://purl.uniprot.org/uniprot/A0A8C6K779 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the syntrophin family.|||Cell junction|||cytoskeleton http://togogenome.org/gene/13146:LOC101878383 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6N8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101877626 ^@ http://purl.uniprot.org/uniprot/A0A8C6J8G6 ^@ Function|||Similarity ^@ Belongs to the pex2/pex10/pex12 family.|||Somewhat implicated in the biogenesis of peroxisomes. http://togogenome.org/gene/13146:LOC101870208 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase d subunit family.|||Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871433 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZU2 ^@ Similarity ^@ Belongs to the CEP63 family. http://togogenome.org/gene/13146:LOC101877571 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ninjurin family.|||Membrane http://togogenome.org/gene/13146:LOC101878386 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the E2F/DP family.|||Nucleus http://togogenome.org/gene/13146:LOC101872525 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM170 family.|||Membrane http://togogenome.org/gene/13146:LOC101880666 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.|||Golgi apparatus membrane|||Membrane http://togogenome.org/gene/13146:LOC101877077 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101869289 ^@ http://purl.uniprot.org/uniprot/A0A8C6K084 ^@ Domain|||Similarity ^@ A pair of annexin repeats may form one binding site for calcium and phospholipid.|||Belongs to the annexin family. http://togogenome.org/gene/13146:LOC101871962 ^@ http://purl.uniprot.org/uniprot/A0A8C6JE58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101879666 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP19 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily. http://togogenome.org/gene/13146:LOC101873060 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYA8 ^@ Similarity|||Subunit ^@ Belongs to the NDUFAF4 family.|||Binds calmodulin. Interacts with NDUFAF3. http://togogenome.org/gene/13146:LOC101872897 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBE1 ^@ Similarity ^@ Belongs to the CoA-transferase III family. http://togogenome.org/gene/13146:LOC101868210 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat PWP2 family.|||nucleolus http://togogenome.org/gene/13146:LOC101871452 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CSM3 family.|||Nucleus|||Plays an important role in the control of DNA replication and the maintenance of replication fork stability. http://togogenome.org/gene/13146:LOC101880336 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7R0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the V-ATPase H subunit family.|||Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.|||V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. http://togogenome.org/gene/13146:LOC101877449 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM39 family.|||Membrane http://togogenome.org/gene/13146:LOC101881103 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC12A transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101870726 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBE2 ^@ Similarity ^@ Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily. http://togogenome.org/gene/13146:LOC101875717 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the snRNP core protein family.|||Nucleus|||cytosol http://togogenome.org/gene/13146:LOC101877772 ^@ http://purl.uniprot.org/uniprot/A0A8C6IM53 ^@ Similarity ^@ Belongs to the phosphatase 2A regulatory subunit B56 family. http://togogenome.org/gene/13146:LOC101872521 ^@ http://purl.uniprot.org/uniprot/A0A8C6J383 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M67A family. CSN5 subfamily.|||synaptic vesicle http://togogenome.org/gene/13146:LOC101868769 ^@ http://purl.uniprot.org/uniprot/A0A8C6J4B0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glucagon family.|||Secreted|||VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder. http://togogenome.org/gene/13146:LOC101873561 ^@ http://purl.uniprot.org/uniprot/A0A8C6K891 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the natriuretic peptide family.|||Secreted http://togogenome.org/gene/13146:LOC101878621 ^@ http://purl.uniprot.org/uniprot/A0A8C6JH07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101871740 ^@ http://purl.uniprot.org/uniprot/A0A8C6N746 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101875882 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCE5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dolichyldiphosphatase family.|||Endoplasmic reticulum membrane|||Membrane|||Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. http://togogenome.org/gene/13146:LOC101871347 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACC family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101870063 ^@ http://purl.uniprot.org/uniprot/A0A8C6JC23 ^@ Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family. http://togogenome.org/gene/13146:LOC101879440 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101876581 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the clusterin family.|||Secreted http://togogenome.org/gene/13146:LOC101881251 ^@ http://purl.uniprot.org/uniprot/A0A8C6K045 ^@ Caution|||Similarity ^@ Belongs to the peptidase M14 family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101881003 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C26 family.|||extracellular space http://togogenome.org/gene/13146:LOC101879183 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the tubulin family.|||Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.|||Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.|||cytoskeleton http://togogenome.org/gene/13146:LOC101869391 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGZ3 ^@ Similarity ^@ Belongs to the G-protein coupled receptor 1 family. http://togogenome.org/gene/13146:LOC101873837 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0P3 ^@ Similarity ^@ Belongs to the MAD1 family. http://togogenome.org/gene/13146:LOC101873976 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY33 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/13146:LOC101870005 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEP7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL2 family. http://togogenome.org/gene/13146:LOC101879585 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGF9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL24 family. http://togogenome.org/gene/13146:LOC101878336 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Z5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Rab family.|||Cell membrane|||Protein transport. http://togogenome.org/gene/13146:LOC101868263 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ80 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAPPC11 family.|||Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.|||cis-Golgi network http://togogenome.org/gene/13146:LOC101881289 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat SCAP family.|||COPII-coated vesicle membrane|||Golgi apparatus membrane http://togogenome.org/gene/13146:LOC101881665 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWF6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the very long-chain fatty acids dehydratase HACD family.|||Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101878686 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cyclin family. Cyclin D subfamily.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101877174 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG30 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AAA ATPase family.|||Cytoplasm http://togogenome.org/gene/13146:LOC101875015 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MCM family.|||Nucleus http://togogenome.org/gene/13146:LOC101872875 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUW6 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101877801 ^@ http://purl.uniprot.org/uniprot/A0A8C6JX53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATR family.|||Membrane http://togogenome.org/gene/13146:LOC101872678 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ERG28 family.|||Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101876055 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1J8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.|||cytoskeleton http://togogenome.org/gene/13146:LOC101875075 ^@ http://purl.uniprot.org/uniprot/A0A8C6N9G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OLFML3 family.|||Secreted http://togogenome.org/gene/13146:LOC101874645 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITN3 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/13146:LOC101876733 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0R3 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101877491 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCW0 ^@ Similarity ^@ Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. http://togogenome.org/gene/13146:LOC101879653 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFZ0 ^@ Similarity ^@ Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. http://togogenome.org/gene/13146:LOC101874960 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876855 ^@ http://purl.uniprot.org/uniprot/A0A8C6JM01 ^@ Similarity ^@ Belongs to the sulfotransferase 1 family. http://togogenome.org/gene/13146:LOC101877279 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXC8 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation. http://togogenome.org/gene/13146:LOC101879467 ^@ http://purl.uniprot.org/uniprot/A0A8C6JIP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.|||Membrane http://togogenome.org/gene/13146:LOC101875267 ^@ http://purl.uniprot.org/uniprot/A0A8C6K815 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.|||Membrane|||Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. http://togogenome.org/gene/13146:LOC101881510 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the mastermind family.|||Nucleus speckle http://togogenome.org/gene/13146:LOC101881632 ^@ http://purl.uniprot.org/uniprot/A0A8C6J351 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101872057 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILZ9 ^@ Similarity ^@ Belongs to the immunoglobulin superfamily. AMIGO family. http://togogenome.org/gene/13146:LOC101868669 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFJ1 ^@ Similarity ^@ Belongs to the TPA1 family. http://togogenome.org/gene/13146:LOC101869352 ^@ http://purl.uniprot.org/uniprot/A0A8C6JK45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.|||Binds with high affinity to CRF receptors 2-alpha and 2-beta.|||Secreted|||Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. http://togogenome.org/gene/13146:LOC101874529 ^@ http://purl.uniprot.org/uniprot/A0A8C6IXF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the WD repeat WDR48 family.|||Endosome|||Late endosome http://togogenome.org/gene/13146:LOC101869382 ^@ http://purl.uniprot.org/uniprot/A0A8C6N786 ^@ Function|||Similarity ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]). http://togogenome.org/gene/13146:LOC101868257 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLH6 ^@ Similarity ^@ Belongs to the DOK family. Type B subfamily. http://togogenome.org/gene/13146:LOC101881098 ^@ http://purl.uniprot.org/uniprot/A0A8C6JBH9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transthyretin family.|||Homotetramer.|||Secreted|||Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. http://togogenome.org/gene/13146:LOC101872833 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal ribosomal protein uS10 family.|||Mitochondrion http://togogenome.org/gene/13146:LOC101873532 ^@ http://purl.uniprot.org/uniprot/A0A8C6J973 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101876740 ^@ http://purl.uniprot.org/uniprot/A0A8C6JF89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TGF-beta family. GDNF subfamily.|||Secreted http://togogenome.org/gene/13146:LOC101876853 ^@ http://purl.uniprot.org/uniprot/A0A8C6JY29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the tetraspanin (TM4SF) family.|||Membrane http://togogenome.org/gene/13146:LOC101880166 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.|||Belongs to the NDC80/HEC1 family.|||Component of the NDC80 complex.|||Nucleus|||kinetochore http://togogenome.org/gene/13146:LOC101872386 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFK9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the histone H2A family.|||Chromosome|||Nucleus|||The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. http://togogenome.org/gene/13146:LOC101880040 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTC2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871853 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase C54 family.|||Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.|||Cytoplasm http://togogenome.org/gene/13146:SOD1 ^@ http://purl.uniprot.org/uniprot/Q802E0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/13146:LOC101879192 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ku70 family.|||Nucleus http://togogenome.org/gene/13146:LOC101875886 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT83 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytospin-A family.|||Involved in cytokinesis and spindle organization. May play a role in actin cytoskeleton organization and microtubule stabilization and hence required for proper cell adhesion and migration.|||May interact with both microtubules and actin cytoskeleton.|||cytoskeleton|||gap junction|||spindle http://togogenome.org/gene/13146:LOC101878236 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN83 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/13146:LOC101872455 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRQ5 ^@ Function|||Similarity ^@ Belongs to the MOZART1 family.|||Required for gamma-tubulin complex recruitment to the centrosome. http://togogenome.org/gene/13146:LOC101877903 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9A3 ^@ Similarity ^@ Belongs to the protein kinase superfamily. Tyr protein kinase family. http://togogenome.org/gene/13146:LOC101878170 ^@ http://purl.uniprot.org/uniprot/A0A8C6J828|||http://purl.uniprot.org/uniprot/A0A8C6J8L6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TALE/MEIS homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101873239 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYG1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101880374 ^@ http://purl.uniprot.org/uniprot/A0A8C6INS3 ^@ Similarity ^@ Belongs to the YY transcription factor family. http://togogenome.org/gene/13146:LOC101874983 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101872037 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAQ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Abd-B homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101875473 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQB1 ^@ Similarity ^@ Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily. http://togogenome.org/gene/13146:LOC101877393 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MAPEG family.|||Membrane http://togogenome.org/gene/13146:LOC101873958 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the amidinotransferase family.|||Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.|||Homodimer.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101874187 ^@ http://purl.uniprot.org/uniprot/A0A8C6J1V0 ^@ Domain|||Similarity ^@ Belongs to the Xin family.|||Xin repeats bind F-actin. http://togogenome.org/gene/13146:LOC101879761 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1N1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ERGIC family.|||Endoplasmic reticulum membrane|||Endoplasmic reticulum-Golgi intermediate compartment membrane|||Golgi apparatus membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays a role in transport between endoplasmic reticulum and Golgi. http://togogenome.org/gene/13146:LOC101880722 ^@ http://purl.uniprot.org/uniprot/A0A8C6JHR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the small GTPase superfamily. Arf family.|||centrosome http://togogenome.org/gene/13146:LOC101869437 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG65 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/13146:LOC101871540 ^@ http://purl.uniprot.org/uniprot/A0A8C6JP91 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATG5 family.|||Conjugated with ATG12.|||Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.|||May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.|||Preautophagosomal structure membrane http://togogenome.org/gene/13146:LOC101877416 ^@ http://purl.uniprot.org/uniprot/A0A8C6JEX2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Homodimer. Heterodimer with HTR1D.|||Membrane http://togogenome.org/gene/13146:LOC101877773 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXC8 ^@ Similarity ^@ Belongs to the FAM83 family. http://togogenome.org/gene/13146:LOC101876992 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGX2 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870618 ^@ http://purl.uniprot.org/uniprot/A0A8C6NF56 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.|||Belongs to the GAMAD family.|||cytoskeleton http://togogenome.org/gene/13146:LOC101871422 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYX0 ^@ Similarity ^@ Belongs to the beta-catenin family. http://togogenome.org/gene/13146:LOC101877124 ^@ http://purl.uniprot.org/uniprot/A0A8C6JGK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Membrane|||Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. http://togogenome.org/gene/13146:LOC101872882 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.|||cytoskeleton http://togogenome.org/gene/13146:LOC101870989 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2V7 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101876995 ^@ http://purl.uniprot.org/uniprot/A0A8C6INF5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101868821 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the intercrine beta (chemokine CC) family.|||Secreted http://togogenome.org/gene/13146:LOC101868509 ^@ http://purl.uniprot.org/uniprot/A0A8C6N876 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family. http://togogenome.org/gene/13146:LOC101881340 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/13146:LOC101876502 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI75 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101868625 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAG4 ^@ Similarity ^@ Belongs to the peptidase C2 family. http://togogenome.org/gene/13146:LOC101867623 ^@ http://purl.uniprot.org/uniprot/A0A8C6N8A7 ^@ Function|||Similarity ^@ Belongs to the MPI phosphatase family.|||Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. http://togogenome.org/gene/13146:LOC101872244 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3B8 ^@ Similarity ^@ Belongs to the acid ceramidase family. http://togogenome.org/gene/13146:LOC101869743 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN28 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the STT3 family.|||Membrane http://togogenome.org/gene/13146:LOC101873762 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRY9 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.|||Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form. http://togogenome.org/gene/13146:LOC101878964 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5X4 ^@ Similarity ^@ Belongs to the PNO1 family. http://togogenome.org/gene/13146:LOC101875114 ^@ http://purl.uniprot.org/uniprot/A0A8C6JLU2 ^@ Similarity ^@ Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. http://togogenome.org/gene/13146:LOC101869983 ^@ http://purl.uniprot.org/uniprot/A0A8C6JN51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DDOST 48 kDa subunit family.|||Component of the oligosaccharyltransferase (OST) complex.|||Endoplasmic reticulum membrane|||Membrane|||Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). http://togogenome.org/gene/13146:LOC101867667 ^@ http://purl.uniprot.org/uniprot/A0A8C6N7V1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||May be involved in vesicle transport between the ER and the Golgi complex.|||Membrane http://togogenome.org/gene/13146:LOC101879908 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY02 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.|||Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.|||Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).|||Cytoplasm|||Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis. http://togogenome.org/gene/13146:LOC101871970 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBQ0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101876074 ^@ http://purl.uniprot.org/uniprot/A0A8C6NBC4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the claudin family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.|||tight junction http://togogenome.org/gene/13146:LOC101871632 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDI1 ^@ Similarity ^@ Belongs to the pleiotrophin family. http://togogenome.org/gene/13146:LOC101869697 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNU3 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/13146:LOC101870452 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the G protein gamma family.|||Cell membrane|||G proteins are composed of 3 units; alpha, beta and gamma.|||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. http://togogenome.org/gene/13146:LOC101881819 ^@ http://purl.uniprot.org/uniprot/A0A8C6IR07 ^@ Similarity ^@ Belongs to the DNA photolyase class-1 family. http://togogenome.org/gene/13146:LOC101877790 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5Z5 ^@ Function|||Similarity ^@ Belongs to the PKI family.|||Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains. http://togogenome.org/gene/13146:LOC101880528 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2N9 ^@ Similarity ^@ Belongs to the chondromodulin-1 family. http://togogenome.org/gene/13146:LOC101871733 ^@ http://purl.uniprot.org/uniprot/A0A8C6K208 ^@ Similarity ^@ Belongs to the ZC3H15/TMA46 family. http://togogenome.org/gene/13146:LOC101873912 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1E3 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101874141 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2M2 ^@ Subcellular Location Annotation ^@ Peroxisome http://togogenome.org/gene/13146:LOC101869146 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI25 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/13146:LOC101880674 ^@ http://purl.uniprot.org/uniprot/A0A8C6NEM7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the endophilin family.|||Membrane http://togogenome.org/gene/13146:LOC101871969 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUE2 ^@ Similarity ^@ Belongs to the HEBP family. http://togogenome.org/gene/13146:LOC101879922 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRI5 ^@ Subcellular Location Annotation ^@ Nucleus speckle http://togogenome.org/gene/13146:LOC101868165 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.|||nucleolus http://togogenome.org/gene/13146:LOC101871082 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDZ9 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.|||DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.|||Nucleus http://togogenome.org/gene/13146:LOC101875900 ^@ http://purl.uniprot.org/uniprot/A0A8C6JYN5 ^@ Function|||Similarity ^@ Belongs to the phospholipase B-like family.|||Putative phospholipase. http://togogenome.org/gene/13146:LOC101871216 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUF5 ^@ Similarity ^@ Belongs to the AccD/PCCB family. http://togogenome.org/gene/13146:LOC101875852 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ04 ^@ Similarity ^@ Belongs to the NOP10 family. http://togogenome.org/gene/13146:LOC101869368 ^@ http://purl.uniprot.org/uniprot/A0A8C6JD84 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 79 family. http://togogenome.org/gene/13146:LOC101879967 ^@ http://purl.uniprot.org/uniprot/A0A8C6IX67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Wnt family.|||Ligand for members of the frizzled family of seven transmembrane receptors.|||extracellular matrix http://togogenome.org/gene/13146:LOC101874293 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2J3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CND3 (condensin subunit 3) family.|||Chromosome http://togogenome.org/gene/13146:LOC101871779 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAE7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL22 family. http://togogenome.org/gene/13146:LOC101879085 ^@ http://purl.uniprot.org/uniprot/A0A8C6IY12 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/13146:LOC101879543 ^@ http://purl.uniprot.org/uniprot/A0A8C6N6T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.|||Belongs to the MCM family.|||Component of the MCM2-7 complex.|||Nucleus http://togogenome.org/gene/13146:LOC101874439 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDP3 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine. http://togogenome.org/gene/13146:LOC101871741 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA1 family.|||Membrane http://togogenome.org/gene/13146:LOC101871639 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAY4 ^@ Similarity|||Subunit ^@ Belongs to the synuclein family.|||May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation. http://togogenome.org/gene/13146:LOC101872138 ^@ http://purl.uniprot.org/uniprot/A0A8C6N861 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the synaptobrevin family.|||Endoplasmic reticulum membrane|||May be involved in vesicle transport between the ER and the Golgi complex.|||Membrane http://togogenome.org/gene/13146:LOC101881188 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKS8 ^@ Similarity ^@ Belongs to the glycosyltransferase 25 family. http://togogenome.org/gene/13146:LOC101873342 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Y8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome c oxidase VIIc family.|||Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).|||Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.|||Membrane|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871325 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4Q6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL13 family. http://togogenome.org/gene/13146:LOC101874791 ^@ http://purl.uniprot.org/uniprot/A0A8C6K497 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||Component of the post-replicative DNA mismatch repair system (MMR). http://togogenome.org/gene/13146:LOC101877955 ^@ http://purl.uniprot.org/uniprot/A0A8C6J353 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101869377 ^@ http://purl.uniprot.org/uniprot/A0A8C6JTX5 ^@ Caution|||Function|||Subcellular Location Annotation ^@ Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Secreted http://togogenome.org/gene/13146:LOC101879431 ^@ http://purl.uniprot.org/uniprot/A0A8C6N837 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101879389 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase epsilon subunit B family.|||Nucleus|||Participates in DNA repair and in chromosomal DNA replication. http://togogenome.org/gene/13146:LOC101881323 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUS1|||http://purl.uniprot.org/uniprot/A0A8C6IWR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the myelin proteolipid protein family.|||Membrane http://togogenome.org/gene/13146:LOC101872090 ^@ http://purl.uniprot.org/uniprot/A0A8C6JXW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the BRX1 family.|||Required for biogenesis of the 60S ribosomal subunit.|||nucleolus http://togogenome.org/gene/13146:LOC101876108 ^@ http://purl.uniprot.org/uniprot/A0A8C6J3I9 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/13146:LOC101869636 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4T5 ^@ Similarity ^@ Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily. http://togogenome.org/gene/13146:LOC101871282 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUE6 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ELO family. ELOVL6 subfamily.|||Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.|||Endoplasmic reticulum membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||N-Glycosylated. http://togogenome.org/gene/13146:LOC101874886 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/13146:LOC101871446 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFI5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.|||Binds to laminin.|||extracellular matrix http://togogenome.org/gene/13146:LOC101867725 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNM9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.|||Belongs to the complex I LYR family.|||Interacts with UQCRFS1.|||Mitochondrion matrix http://togogenome.org/gene/13146:LOC101878194 ^@ http://purl.uniprot.org/uniprot/A0A8C6IPZ0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101869595 ^@ http://purl.uniprot.org/uniprot/A0A8C6JPQ0 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/13146:LOC101872077 ^@ http://purl.uniprot.org/uniprot/A0A8C6JT32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the clathrin heavy chain family.|||Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.|||Cytoplasmic vesicle membrane|||Membrane|||coated pit http://togogenome.org/gene/13146:LOC101871329 ^@ http://purl.uniprot.org/uniprot/A0A8C6JI82 ^@ Similarity ^@ Belongs to the acetyltransferase family. GNAT subfamily. http://togogenome.org/gene/13146:LOC101871692 ^@ http://purl.uniprot.org/uniprot/A0A8C6JNK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRP38 family.|||Component of the spliceosome B complex.|||Involved in pre-mRNA splicing as a component of the spliceosome.|||Nucleus http://togogenome.org/gene/13146:LOC101874875 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISH1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. http://togogenome.org/gene/13146:LOC101877244 ^@ http://purl.uniprot.org/uniprot/A0A8C6JDI6 ^@ Similarity ^@ Belongs to the LCA5 family. http://togogenome.org/gene/13146:LOC101869638 ^@ http://purl.uniprot.org/uniprot/A0A8C6JRR6 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101880876 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISI4 ^@ Similarity ^@ Belongs to the synapsin family. http://togogenome.org/gene/13146:LOC101878832 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MUSTANG family.|||Nucleus http://togogenome.org/gene/13146:LOC101873075 ^@ http://purl.uniprot.org/uniprot/A0A8C6ITR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sphingomyelin synthase family.|||Membrane http://togogenome.org/gene/13146:LOC101870068 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG81 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family. AK3 subfamily.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.|||Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.|||Mitochondrion matrix|||Monomer. http://togogenome.org/gene/13146:LOC101880148 ^@ http://purl.uniprot.org/uniprot/A0A8C6JJV2 ^@ Similarity|||Subcellular Location Annotation ^@ Basolateral cell membrane|||Belongs to the potassium channel family. KQT (TC 1.A.1.15) subfamily. Kv7.1/KCNQ1 sub-subfamily.|||Cell membrane|||Cytoplasmic vesicle membrane|||Endoplasmic reticulum|||Lateral cell membrane|||Membrane|||Membrane raft http://togogenome.org/gene/13146:LOC101872406 ^@ http://purl.uniprot.org/uniprot/A0A8C6N951 ^@ Similarity ^@ Belongs to the TFIIE alpha subunit family. http://togogenome.org/gene/13146:LOC101873926 ^@ http://purl.uniprot.org/uniprot/A0A8C6IT34 ^@ Subcellular Location Annotation ^@ Chromosome|||Nucleus speckle http://togogenome.org/gene/13146:LOC101875050 ^@ http://purl.uniprot.org/uniprot/A0A8C6J7G7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL30 family. http://togogenome.org/gene/13146:LOC101881088 ^@ http://purl.uniprot.org/uniprot/A0A8C6J341 ^@ Domain|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DHHC palmitoyltransferase family.|||Membrane|||The DHHC domain is required for palmitoyltransferase activity. http://togogenome.org/gene/13146:LOC101874593 ^@ http://purl.uniprot.org/uniprot/A0A8C6IYP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). http://togogenome.org/gene/13146:LOC101867757 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6R3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family.|||Nucleus http://togogenome.org/gene/13146:LOC101875611 ^@ http://purl.uniprot.org/uniprot/A0A8C6J562 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.|||Membrane http://togogenome.org/gene/13146:LOC101869312 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Membrane|||Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. http://togogenome.org/gene/13146:LOC101878061 ^@ http://purl.uniprot.org/uniprot/A0A8C6NGV1 ^@ Similarity ^@ Belongs to the actin family. http://togogenome.org/gene/13146:LOC101868815 ^@ http://purl.uniprot.org/uniprot/A0A8C6K1Y0 ^@ Similarity ^@ Belongs to the CSN12 family. http://togogenome.org/gene/13146:LOC101878446 ^@ http://purl.uniprot.org/uniprot/A0A8C6IME7 ^@ Function|||Subcellular Location Annotation ^@ Nucleus|||Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.|||cytosol http://togogenome.org/gene/13146:LOC101879292 ^@ http://purl.uniprot.org/uniprot/A0A8C6JES8 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101870267 ^@ http://purl.uniprot.org/uniprot/A0A8C6NE06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the retinoblastoma protein (RB) family.|||Nucleus http://togogenome.org/gene/13146:LOC101868742 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDP5 ^@ Similarity ^@ Belongs to the VPS26 family. http://togogenome.org/gene/13146:LOC101870638 ^@ http://purl.uniprot.org/uniprot/A0A8C6K4A5 ^@ Similarity ^@ Belongs to the intermediate filament family. http://togogenome.org/gene/13146:LOC101874988 ^@ http://purl.uniprot.org/uniprot/A0A8C6IU42 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101877879 ^@ http://purl.uniprot.org/uniprot/A0A8C6IVE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAM174 family.|||Membrane http://togogenome.org/gene/13146:LOC101869380 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMF1 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/13146:LOC101878340 ^@ http://purl.uniprot.org/uniprot/A0A8C6IST0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.|||Belongs to the SPARC family.|||Membrane|||basement membrane http://togogenome.org/gene/13146:LOC101879859 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ubiquitin family. SUMO subfamily.|||Nucleus http://togogenome.org/gene/13146:LOC101877499 ^@ http://purl.uniprot.org/uniprot/A0A8C6JKC4 ^@ Similarity ^@ Belongs to the TGF-beta family. http://togogenome.org/gene/13146:LOC101874048 ^@ http://purl.uniprot.org/uniprot/A0A8C6J9W9 ^@ Similarity ^@ Belongs to the protein kinase superfamily. http://togogenome.org/gene/13146:LOC101869011 ^@ http://purl.uniprot.org/uniprot/A0A8C6ILY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the nuclear hormone receptor family. NR1 subfamily.|||Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.|||Nucleus http://togogenome.org/gene/13146:LOC101872589 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2B5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Cell surface|||Endosome|||Membrane http://togogenome.org/gene/13146:LOC101878276 ^@ http://purl.uniprot.org/uniprot/A0A8C6JUD4 ^@ Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. http://togogenome.org/gene/13146:LOC101878941 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFL0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Antp homeobox family.|||Nucleus http://togogenome.org/gene/13146:LOC101878468 ^@ http://purl.uniprot.org/uniprot/A0A8C6JFI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873807 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CNOT9 family.|||P-body http://togogenome.org/gene/13146:LOC101875800 ^@ http://purl.uniprot.org/uniprot/A0A8C6IQ73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the G-protein coupled receptor 1 family.|||Cell membrane|||Early endosome|||Endosome|||Late endosome|||Lysosome|||Membrane http://togogenome.org/gene/13146:LOC101877775 ^@ http://purl.uniprot.org/uniprot/A0A8C6JL69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dwarfin/SMAD family.|||Cytoplasm|||Nucleus http://togogenome.org/gene/13146:LOC101869136 ^@ http://purl.uniprot.org/uniprot/A0A8C6K3Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC4 subfamily.|||Chromosome|||Nucleus http://togogenome.org/gene/13146:LOC101870009 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sulfotransferase 1 family. NDST subfamily.|||Membrane http://togogenome.org/gene/13146:LOC101872853 ^@ http://purl.uniprot.org/uniprot/A0A8C6NDE6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.|||Belongs to the complex I NDUFB2 subunit family.|||Complex I is composed of 45 different subunits.|||Mitochondrion inner membrane http://togogenome.org/gene/13146:LOC101871926 ^@ http://purl.uniprot.org/uniprot/A0A8C6NER1 ^@ Similarity ^@ Belongs to the SAPAP family. http://togogenome.org/gene/13146:LOC101879008 ^@ http://purl.uniprot.org/uniprot/A0A8C6NFU0 ^@ Caution|||Similarity ^@ Belongs to the peptidase M10A family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101880363 ^@ http://purl.uniprot.org/uniprot/A0A8C6JW18|||http://purl.uniprot.org/uniprot/A0A8C6K0K1 ^@ Function|||Subcellular Location Annotation ^@ Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.|||Cytoplasm http://togogenome.org/gene/13146:LOC101879643 ^@ http://purl.uniprot.org/uniprot/A0A8C6KAK8 ^@ Subcellular Location Annotation ^@ cell cortex|||dendritic spine http://togogenome.org/gene/13146:LOC101869702 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG06 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heat shock protein 70 family.|||Endoplasmic reticulum lumen http://togogenome.org/gene/13146:LOC101878973 ^@ http://purl.uniprot.org/uniprot/A0A8C6NA46 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/13146:LOC101872975 ^@ http://purl.uniprot.org/uniprot/A0A8C6JV73 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DIPK family.|||Endoplasmic reticulum membrane http://togogenome.org/gene/13146:LOC101868030 ^@ http://purl.uniprot.org/uniprot/A0A8C6JVI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vestigial family.|||May act as a specific coactivator for the mammalian TEFs.|||Nucleus http://togogenome.org/gene/13146:LOC101878074 ^@ http://purl.uniprot.org/uniprot/A0A8C6J2Y3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HIBADH-related family. NP60 subfamily.|||Chromosome http://togogenome.org/gene/13146:LOC101877377 ^@ http://purl.uniprot.org/uniprot/A0A8C6IRU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complexin/synaphin family.|||Synapse http://togogenome.org/gene/13146:LOC101880812 ^@ http://purl.uniprot.org/uniprot/A0A8C6NB94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101873623 ^@ http://purl.uniprot.org/uniprot/A0A8C6NG02 ^@ Caution|||Similarity ^@ Belongs to the semaphorin family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/13146:LOC101871821 ^@ http://purl.uniprot.org/uniprot/A0A8C6IWV7 ^@ Similarity ^@ Belongs to the WD repeat RAPTOR family. http://togogenome.org/gene/13146:LOC101880966 ^@ http://purl.uniprot.org/uniprot/A0A8C6J6M9|||http://purl.uniprot.org/uniprot/A0A8C6J8G8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.|||Endomembrane system|||Golgi apparatus|||Membrane|||Mitochondrion outer membrane|||Peroxisome|||clathrin-coated pit|||cytosol|||synaptic vesicle membrane http://togogenome.org/gene/13146:LOC101872186 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5D1 ^@ Similarity ^@ Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. http://togogenome.org/gene/13146:LOC101873998 ^@ http://purl.uniprot.org/uniprot/A0A8C6IUU1 ^@ Similarity ^@ Belongs to the PP1 inhibitor family. http://togogenome.org/gene/13146:LOC101874250 ^@ http://purl.uniprot.org/uniprot/A0A8C6J0I7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RNF152 family.|||Lysosome membrane|||Membrane http://togogenome.org/gene/13146:LOC101870158 ^@ http://purl.uniprot.org/uniprot/A0A8C6NAT4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ligand-gated ion channel (TC 1.A.9) family.|||Cell membrane|||Membrane|||Postsynaptic cell membrane|||Synaptic cell membrane http://togogenome.org/gene/13146:LOC101876580 ^@ http://purl.uniprot.org/uniprot/A0A8C6ISX9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/13146:LOC101874578 ^@ http://purl.uniprot.org/uniprot/A0A8C6K0Y0 ^@ Subcellular Location Annotation ^@ Midbody|||centriole|||spindle pole http://togogenome.org/gene/13146:LOC101874750 ^@ http://purl.uniprot.org/uniprot/A0A8C6JMU6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ELP3 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs. http://togogenome.org/gene/13146:LOC101881588 ^@ http://purl.uniprot.org/uniprot/A0A8C6IZ44 ^@ Similarity ^@ Belongs to the peptidase M10A family. http://togogenome.org/gene/13146:LOC101874792 ^@ http://purl.uniprot.org/uniprot/A0A8C6J5T9 ^@ Similarity ^@ Belongs to the spectrin family. http://togogenome.org/gene/13146:LOC101871065 ^@ http://purl.uniprot.org/uniprot/A0A8C6NCT8 ^@ Cofactor|||Similarity ^@ Belongs to the eukaryotic GSH synthase family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/13146:LOC101873853 ^@ http://purl.uniprot.org/uniprot/A0A8C6JG97 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/13146:LOC101869762 ^@ http://purl.uniprot.org/uniprot/A0A8C6JS10 ^@ Similarity ^@ Belongs to the UFD1 family. http://togogenome.org/gene/13146:LOC101875713 ^@ http://purl.uniprot.org/uniprot/A0A8C6JCJ6 ^@ Similarity ^@ Belongs to the mitoguardin family. http://togogenome.org/gene/13146:LOC101880144 ^@ http://purl.uniprot.org/uniprot/A0A8C6K2S1 ^@ Similarity ^@ Belongs to the TTC38 family. http://togogenome.org/gene/13146:LOC101872468 ^@ http://purl.uniprot.org/uniprot/A0A8C6JWS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.|||Belongs to the dynein light intermediate chain family.|||Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).|||cytoskeleton http://togogenome.org/gene/13146:CAT ^@ http://purl.uniprot.org/uniprot/Q802D8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the catalase family.|||Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.|||Peroxisome http://togogenome.org/gene/13146:LOC101877144 ^@ http://purl.uniprot.org/uniprot/A0A8C6JAW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SMC family. SMC3 subfamily.|||Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.|||Nucleus|||centromere