http://togogenome.org/gene/1294273:ROSELON_RS16180 ^@ http://purl.uniprot.org/uniprot/W8ST79 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS00190 ^@ http://purl.uniprot.org/uniprot/W8RXH6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1294273:ROSELON_RS10085 ^@ http://purl.uniprot.org/uniprot/W8S2T2 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1294273:ROSELON_RS04990 ^@ http://purl.uniprot.org/uniprot/W8RQP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS15590 ^@ http://purl.uniprot.org/uniprot/W8RWM7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1294273:ROSELON_RS12040 ^@ http://purl.uniprot.org/uniprot/W8SQT5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1294273:ROSELON_RS11700 ^@ http://purl.uniprot.org/uniprot/W8RUB9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1294273:ROSELON_RS09230 ^@ http://purl.uniprot.org/uniprot/W8S296 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1294273:ROSELON_RS12185 ^@ http://purl.uniprot.org/uniprot/W8SQZ8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS07740 ^@ http://purl.uniprot.org/uniprot/W8RS84 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS08065 ^@ http://purl.uniprot.org/uniprot/W8RSD7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. http://togogenome.org/gene/1294273:ROSELON_RS00290 ^@ http://purl.uniprot.org/uniprot/W8RNF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the COX11/CtaG family.|||Cell inner membrane|||Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I. http://togogenome.org/gene/1294273:ROSELON_RS15915 ^@ http://purl.uniprot.org/uniprot/W8RWT7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1294273:ROSELON_RS05260 ^@ http://purl.uniprot.org/uniprot/W8S409 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1294273:ROSELON_RS07825 ^@ http://purl.uniprot.org/uniprot/W8S5E3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1294273:ROSELON_RS07100 ^@ http://purl.uniprot.org/uniprot/W8RS00 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS15850 ^@ http://purl.uniprot.org/uniprot/W8RWS2 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1294273:ROSELON_RS05525 ^@ http://purl.uniprot.org/uniprot/W8S0B3 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1294273:ROSELON_RS09280 ^@ http://purl.uniprot.org/uniprot/W8S644 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1294273:ROSELON_RS02075 ^@ http://purl.uniprot.org/uniprot/W8RYH5 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1294273:ROSELON_RS08220 ^@ http://purl.uniprot.org/uniprot/W8S5L2 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1294273:ROSELON_RS08130 ^@ http://purl.uniprot.org/uniprot/W8RSK3 ^@ Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1294273:ROSELON_RS04915 ^@ http://purl.uniprot.org/uniprot/W8RQW3 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1294273:ROSELON_RS14975 ^@ http://purl.uniprot.org/uniprot/W8SSJ9 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/1294273:ROSELON_RS14370 ^@ http://purl.uniprot.org/uniprot/W8SS53 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1294273:ROSELON_RS06495 ^@ http://purl.uniprot.org/uniprot/W8RRP3 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/1294273:ROSELON_RS07735 ^@ http://purl.uniprot.org/uniprot/W8RSE7 ^@ Function|||Subcellular Location Annotation ^@ Could be a virulence factor.|||Membrane|||Secreted http://togogenome.org/gene/1294273:ROSELON_RS14620 ^@ http://purl.uniprot.org/uniprot/W8SSE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1294273:ROSELON_RS03580 ^@ http://purl.uniprot.org/uniprot/W8SKW9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04355 ^@ http://purl.uniprot.org/uniprot/W8SLB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS15795 ^@ http://purl.uniprot.org/uniprot/W8RWE4 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1294273:ROSELON_RS09310 ^@ http://purl.uniprot.org/uniprot/W8S2B1 ^@ Caution|||Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS14635 ^@ http://purl.uniprot.org/uniprot/W8RVW9 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1294273:ROSELON_RS07330 ^@ http://purl.uniprot.org/uniprot/W8SN67 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1294273:ROSELON_RS06195 ^@ http://purl.uniprot.org/uniprot/W8RR99 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1294273:ROSELON_RS12365 ^@ http://purl.uniprot.org/uniprot/W8S459 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1294273:ROSELON_RS02145 ^@ http://purl.uniprot.org/uniprot/W8S2G8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1294273:ROSELON_RS08670 ^@ http://purl.uniprot.org/uniprot/W8SNU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15845 ^@ http://purl.uniprot.org/uniprot/W8RWF3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia. http://togogenome.org/gene/1294273:ROSELON_RS00370 ^@ http://purl.uniprot.org/uniprot/W8RN48 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1294273:ROSELON_RS03225 ^@ http://purl.uniprot.org/uniprot/W8RPL3 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1294273:ROSELON_RS14125 ^@ http://purl.uniprot.org/uniprot/W8S510 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS04655 ^@ http://purl.uniprot.org/uniprot/W8RZV3 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1294273:ROSELON_RS16745 ^@ http://purl.uniprot.org/uniprot/W8RWV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS08780 ^@ http://purl.uniprot.org/uniprot/W8RSW5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1294273:ROSELON_RS15570 ^@ http://purl.uniprot.org/uniprot/W8SSV0 ^@ Similarity ^@ Belongs to the TelA family. http://togogenome.org/gene/1294273:ROSELON_RS11135 ^@ http://purl.uniprot.org/uniprot/W8RU05 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS07855 ^@ http://purl.uniprot.org/uniprot/W8S1K5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS06065 ^@ http://purl.uniprot.org/uniprot/W8S0K6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1294273:ROSELON_RS00285 ^@ http://purl.uniprot.org/uniprot/W8RXJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14090 ^@ http://purl.uniprot.org/uniprot/W8SRZ2 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1294273:ROSELON_RS16820 ^@ http://purl.uniprot.org/uniprot/W8RWX0 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1294273:ROSELON_RS05080 ^@ http://purl.uniprot.org/uniprot/W8S036 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ChlB/BchB/BchZ family.|||Chlorophyllide reductase is composed of three subunits; BchX, BchY and BchZ. Forms a heterodimer of one BchY and one BchZ subunit.|||Converts chlorophylls (Chl) into bacteriochlorophylls (BChl) by reducing ring B of the tetrapyrrole. http://togogenome.org/gene/1294273:ROSELON_RS05785 ^@ http://purl.uniprot.org/uniprot/W8RRB2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1294273:ROSELON_RS16070 ^@ http://purl.uniprot.org/uniprot/W8RWW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS04980 ^@ http://purl.uniprot.org/uniprot/W8S018 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1294273:ROSELON_RS05645 ^@ http://purl.uniprot.org/uniprot/W8SM32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS11130 ^@ http://purl.uniprot.org/uniprot/W8RU17 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS09330 ^@ http://purl.uniprot.org/uniprot/W8RT04 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1294273:ROSELON_RS07535 ^@ http://purl.uniprot.org/uniprot/W8RS49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS01075 ^@ http://purl.uniprot.org/uniprot/W8RXX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS01610 ^@ http://purl.uniprot.org/uniprot/W8RP45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS02650 ^@ http://purl.uniprot.org/uniprot/W8RYS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS06715 ^@ http://purl.uniprot.org/uniprot/W8S0X5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1294273:ROSELON_RS07335 ^@ http://purl.uniprot.org/uniprot/W8S573 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1294273:ROSELON_RS00650 ^@ http://purl.uniprot.org/uniprot/W8S1I8 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS04105 ^@ http://purl.uniprot.org/uniprot/W8RQ36 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1294273:ROSELON_RS08090 ^@ http://purl.uniprot.org/uniprot/W8RSE2 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/1294273:ROSELON_RS07245 ^@ http://purl.uniprot.org/uniprot/W8S1B3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1294273:ROSELON_RS13410 ^@ http://purl.uniprot.org/uniprot/W8S4N0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS06775 ^@ http://purl.uniprot.org/uniprot/W8RRM1 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1294273:ROSELON_RS06835 ^@ http://purl.uniprot.org/uniprot/W8S101 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/1294273:ROSELON_RS03780 ^@ http://purl.uniprot.org/uniprot/W8S382 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS13540 ^@ http://purl.uniprot.org/uniprot/W8SRM9 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1294273:ROSELON_RS11720 ^@ http://purl.uniprot.org/uniprot/W8S3Q0 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1294273:ROSELON_RS10885 ^@ http://purl.uniprot.org/uniprot/W8RTW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS05845 ^@ http://purl.uniprot.org/uniprot/W8S4B9 ^@ Similarity ^@ Belongs to the transglycosylase Slt family.|||Belongs to the virb1 family. http://togogenome.org/gene/1294273:ROSELON_RS09505 ^@ http://purl.uniprot.org/uniprot/W8RT93 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS16170 ^@ http://purl.uniprot.org/uniprot/W8RWK9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1294273:ROSELON_RS06335 ^@ http://purl.uniprot.org/uniprot/W8S4K0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS05100 ^@ http://purl.uniprot.org/uniprot/W8S3Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the reaction center PufL/M/PsbA/D family.|||Cellular chromatophore membrane|||Membrane|||The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS08185 ^@ http://purl.uniprot.org/uniprot/W8RSF8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS01595 ^@ http://purl.uniprot.org/uniprot/W8SJV0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.|||Belongs to the antenna complex beta subunit family.|||Cell inner membrane|||Membrane|||The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components. http://togogenome.org/gene/1294273:ROSELON_RS14330 ^@ http://purl.uniprot.org/uniprot/W8S544 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS15265 ^@ http://purl.uniprot.org/uniprot/W8S5P1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1294273:ROSELON_RS14280 ^@ http://purl.uniprot.org/uniprot/W8S534 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS04975 ^@ http://purl.uniprot.org/uniprot/W8S3W5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS10320 ^@ http://purl.uniprot.org/uniprot/W8S2X9 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1294273:ROSELON_RS13450 ^@ http://purl.uniprot.org/uniprot/W8SRL5 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1294273:ROSELON_RS12785 ^@ http://purl.uniprot.org/uniprot/W8RUW6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS12425 ^@ http://purl.uniprot.org/uniprot/W8RUU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1294273:ROSELON_RS05675 ^@ http://purl.uniprot.org/uniprot/W8S486 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS06010 ^@ http://purl.uniprot.org/uniprot/W8SM99 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS13985 ^@ http://purl.uniprot.org/uniprot/W8RVP6 ^@ Caution|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS08035 ^@ http://purl.uniprot.org/uniprot/W8RSI8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1294273:ROSELON_RS16565 ^@ http://purl.uniprot.org/uniprot/W8RWR9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS05040 ^@ http://purl.uniprot.org/uniprot/W8RQQ0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1294273:ROSELON_RS05820 ^@ http://purl.uniprot.org/uniprot/W8S4B6 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1294273:ROSELON_RS13370 ^@ http://purl.uniprot.org/uniprot/W8SRK0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1294273:ROSELON_RS14605 ^@ http://purl.uniprot.org/uniprot/W8RVW7 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1294273:ROSELON_RS09360 ^@ http://purl.uniprot.org/uniprot/W8SP93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS11920 ^@ http://purl.uniprot.org/uniprot/W8S3T3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1294273:ROSELON_RS16290 ^@ http://purl.uniprot.org/uniprot/W8RX10 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS12440 ^@ http://purl.uniprot.org/uniprot/W8S470 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1294273:ROSELON_RS16845 ^@ http://purl.uniprot.org/uniprot/W8RWX6 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1294273:ROSELON_RS12980 ^@ http://purl.uniprot.org/uniprot/W8RUZ8 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/1294273:ROSELON_RS06085 ^@ http://purl.uniprot.org/uniprot/W8S4G3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1294273:ROSELON_RS03100 ^@ http://purl.uniprot.org/uniprot/W8S2X0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1294273:ROSELON_RS02730 ^@ http://purl.uniprot.org/uniprot/W8RPE9 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS15840 ^@ http://purl.uniprot.org/uniprot/W8S5Z4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS16960 ^@ http://purl.uniprot.org/uniprot/W8S6H4 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1294273:ROSELON_RS15150 ^@ http://purl.uniprot.org/uniprot/W8S971 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS14100 ^@ http://purl.uniprot.org/uniprot/W8S505 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation. http://togogenome.org/gene/1294273:ROSELON_RS00810 ^@ http://purl.uniprot.org/uniprot/W8RNQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS09455 ^@ http://purl.uniprot.org/uniprot/W8RT85 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1294273:ROSELON_RS14400 ^@ http://purl.uniprot.org/uniprot/W8S8R9 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS15830 ^@ http://purl.uniprot.org/uniprot/W8ST07 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1294273:ROSELON_RS09865 ^@ http://purl.uniprot.org/uniprot/W8RTC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS18125 ^@ http://purl.uniprot.org/uniprot/W8S0D4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1294273:ROSELON_RS02630 ^@ http://purl.uniprot.org/uniprot/W8RPQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS07650 ^@ http://purl.uniprot.org/uniprot/W8RS67 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/1294273:ROSELON_RS00110 ^@ http://purl.uniprot.org/uniprot/W8RN13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1294273:ROSELON_RS16955 ^@ http://purl.uniprot.org/uniprot/W8SA31 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1294273:ROSELON_RS05910 ^@ http://purl.uniprot.org/uniprot/W8SM80 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS02685 ^@ http://purl.uniprot.org/uniprot/W8RPE1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS14665 ^@ http://purl.uniprot.org/uniprot/W8SSF3 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1294273:ROSELON_RS01480 ^@ http://purl.uniprot.org/uniprot/W8S201 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1294273:ROSELON_RS12720 ^@ http://purl.uniprot.org/uniprot/W8SR79 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS01500 ^@ http://purl.uniprot.org/uniprot/W8S204 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS11450 ^@ http://purl.uniprot.org/uniprot/W8S756 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1294273:ROSELON_RS00120 ^@ http://purl.uniprot.org/uniprot/W8S1A3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS03940 ^@ http://purl.uniprot.org/uniprot/W8RZE5 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1294273:ROSELON_RS00800 ^@ http://purl.uniprot.org/uniprot/W8S1M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS05180 ^@ http://purl.uniprot.org/uniprot/W8RQS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PucC family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS08760 ^@ http://purl.uniprot.org/uniprot/W8RSQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ExbB/TolQ family.|||Cell inner membrane|||Membrane|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1294273:ROSELON_RS12305 ^@ http://purl.uniprot.org/uniprot/W8S7Q8 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1294273:ROSELON_RS09140 ^@ http://purl.uniprot.org/uniprot/W8SP50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1294273:ROSELON_RS09710 ^@ http://purl.uniprot.org/uniprot/W8RTA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10070 ^@ http://purl.uniprot.org/uniprot/W8RTI9 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS00255 ^@ http://purl.uniprot.org/uniprot/W8S1C7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS07410 ^@ http://purl.uniprot.org/uniprot/W8S587 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1294273:ROSELON_RS09715 ^@ http://purl.uniprot.org/uniprot/W8SPJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS12590 ^@ http://purl.uniprot.org/uniprot/W8SR58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS02395 ^@ http://purl.uniprot.org/uniprot/W8S2K2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS10095 ^@ http://purl.uniprot.org/uniprot/W8RTF2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS11365 ^@ http://purl.uniprot.org/uniprot/W8RU54 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1294273:ROSELON_RS06205 ^@ http://purl.uniprot.org/uniprot/W8S4I2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1294273:ROSELON_RS00785 ^@ http://purl.uniprot.org/uniprot/W8RNP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS10580 ^@ http://purl.uniprot.org/uniprot/W8RTQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07220 ^@ http://purl.uniprot.org/uniprot/W8S1B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1294273:ROSELON_RS12730 ^@ http://purl.uniprot.org/uniprot/W8S4B5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00875 ^@ http://purl.uniprot.org/uniprot/W8RNR6 ^@ Similarity ^@ Belongs to the complex I 24 kDa subunit family. http://togogenome.org/gene/1294273:ROSELON_RS00070 ^@ http://purl.uniprot.org/uniprot/W8S197 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS10465 ^@ http://purl.uniprot.org/uniprot/W8S2Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS09125 ^@ http://purl.uniprot.org/uniprot/W8S277 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1294273:ROSELON_RS13890 ^@ http://purl.uniprot.org/uniprot/W8SRV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1294273:ROSELON_RS15765 ^@ http://purl.uniprot.org/uniprot/W8S5Y3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1294273:ROSELON_RS16205 ^@ http://purl.uniprot.org/uniprot/W8ST84 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/1294273:ROSELON_RS10175 ^@ http://purl.uniprot.org/uniprot/W8RTK9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS11550 ^@ http://purl.uniprot.org/uniprot/W8S3L7 ^@ Function|||Similarity ^@ Belongs to the bacterioferritin family.|||Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex. http://togogenome.org/gene/1294273:ROSELON_RS14440 ^@ http://purl.uniprot.org/uniprot/W8RVZ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family. ParE type 1 subfamily.|||Heterotetramer composed of ParC and ParE.|||Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule. http://togogenome.org/gene/1294273:ROSELON_RS08180 ^@ http://purl.uniprot.org/uniprot/W8RSL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS11615 ^@ http://purl.uniprot.org/uniprot/W8S7A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS07935 ^@ http://purl.uniprot.org/uniprot/W8SNF7 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS15025 ^@ http://purl.uniprot.org/uniprot/W8S954 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1294273:ROSELON_RS13790 ^@ http://purl.uniprot.org/uniprot/W8SRT1 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1294273:ROSELON_RS11370 ^@ http://purl.uniprot.org/uniprot/W8SQD8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1294273:ROSELON_RS09235 ^@ http://purl.uniprot.org/uniprot/W8RT50 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1294273:ROSELON_RS18580 ^@ http://purl.uniprot.org/uniprot/W8S2D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04485 ^@ http://purl.uniprot.org/uniprot/W8RZR2 ^@ Function|||Similarity ^@ Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.|||Belongs to the Nudix hydrolase family. RppH subfamily. http://togogenome.org/gene/1294273:ROSELON_RS01055 ^@ http://purl.uniprot.org/uniprot/W8RNV0 ^@ Cofactor|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1294273:ROSELON_RS14935 ^@ http://purl.uniprot.org/uniprot/W8S938 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PdxA family.|||Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).|||Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).|||Cytoplasm|||Homodimer.|||The active site is located at the dimer interface. http://togogenome.org/gene/1294273:ROSELON_RS10340 ^@ http://purl.uniprot.org/uniprot/W8S6N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS08325 ^@ http://purl.uniprot.org/uniprot/W8RSN3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS08405 ^@ http://purl.uniprot.org/uniprot/W8RSI9 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1294273:ROSELON_RS04060 ^@ http://purl.uniprot.org/uniprot/W8SL55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1294273:ROSELON_RS11950 ^@ http://purl.uniprot.org/uniprot/W8S3T9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS04660 ^@ http://purl.uniprot.org/uniprot/W8RQP2 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1294273:ROSELON_RS10245 ^@ http://purl.uniprot.org/uniprot/W8RTM2 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS10730 ^@ http://purl.uniprot.org/uniprot/W8S346 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1294273:ROSELON_RS14820 ^@ http://purl.uniprot.org/uniprot/W8RVZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07055 ^@ http://purl.uniprot.org/uniprot/W8SMY8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS05430 ^@ http://purl.uniprot.org/uniprot/W8SLY9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS04045 ^@ http://purl.uniprot.org/uniprot/W8RZG5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1294273:ROSELON_RS02475 ^@ http://purl.uniprot.org/uniprot/W8RYP9 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS02605 ^@ http://purl.uniprot.org/uniprot/W8RPQ0 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1294273:ROSELON_RS06230 ^@ http://purl.uniprot.org/uniprot/W8SME3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1294273:ROSELON_RS11395 ^@ http://purl.uniprot.org/uniprot/W8SQE3 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/1294273:ROSELON_RS08865 ^@ http://purl.uniprot.org/uniprot/W8RSY0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1294273:ROSELON_RS14575 ^@ http://purl.uniprot.org/uniprot/W8S5C0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS05055 ^@ http://purl.uniprot.org/uniprot/W8S030 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1294273:ROSELON_RS03860 ^@ http://purl.uniprot.org/uniprot/W8S397 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1294273:ROSELON_RS06340 ^@ http://purl.uniprot.org/uniprot/W8S0Q5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS04710 ^@ http://purl.uniprot.org/uniprot/W8RQT2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00570 ^@ http://purl.uniprot.org/uniprot/W8S1H5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00300 ^@ http://purl.uniprot.org/uniprot/W8SJ62 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Interacts with CtaA.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10375 ^@ http://purl.uniprot.org/uniprot/W8RTN9 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1294273:ROSELON_RS16020 ^@ http://purl.uniprot.org/uniprot/W8ST49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS09840 ^@ http://purl.uniprot.org/uniprot/W8RTB7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS09810 ^@ http://purl.uniprot.org/uniprot/W8RTB5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS08700 ^@ http://purl.uniprot.org/uniprot/W8S5V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1294273:ROSELON_RS13860 ^@ http://purl.uniprot.org/uniprot/W8RVM1 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1294273:ROSELON_RS10450 ^@ http://purl.uniprot.org/uniprot/W8RTM5 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1294273:ROSELON_RS05980 ^@ http://purl.uniprot.org/uniprot/W8RRF3 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the WrbA family.|||Binds 1 FMN per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS00700 ^@ http://purl.uniprot.org/uniprot/W8RNM6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1294273:ROSELON_RS15250 ^@ http://purl.uniprot.org/uniprot/W8RWG7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04595 ^@ http://purl.uniprot.org/uniprot/W8RQE2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS07190 ^@ http://purl.uniprot.org/uniprot/W8S549 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS14845 ^@ http://purl.uniprot.org/uniprot/W8RW02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00410 ^@ http://purl.uniprot.org/uniprot/W8RXL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS09470 ^@ http://purl.uniprot.org/uniprot/W8S688 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1294273:ROSELON_RS14250 ^@ http://purl.uniprot.org/uniprot/W8S8N5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14955 ^@ http://purl.uniprot.org/uniprot/W8SSJ5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1294273:ROSELON_RS14775 ^@ http://purl.uniprot.org/uniprot/W8RVZ0 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1294273:ROSELON_RS06825 ^@ http://purl.uniprot.org/uniprot/W8SMS6 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1294273:ROSELON_RS01255 ^@ http://purl.uniprot.org/uniprot/W8S1W2 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1294273:ROSELON_RS00310 ^@ http://purl.uniprot.org/uniprot/W8RXJ4 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1294273:ROSELON_RS13880 ^@ http://purl.uniprot.org/uniprot/W8RVE9 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/1294273:ROSELON_RS01850 ^@ http://purl.uniprot.org/uniprot/W8RYC6 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1294273:ROSELON_RS08740 ^@ http://purl.uniprot.org/uniprot/W8SNW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1294273:ROSELON_RS13960 ^@ http://purl.uniprot.org/uniprot/W8RVP0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1294273:ROSELON_RS14485 ^@ http://purl.uniprot.org/uniprot/W8RVR8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1294273:ROSELON_RS16500 ^@ http://purl.uniprot.org/uniprot/W8STC5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1294273:ROSELON_RS03495 ^@ http://purl.uniprot.org/uniprot/W8RZ62 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1294273:ROSELON_RS03885 ^@ http://purl.uniprot.org/uniprot/W8S3A2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1294273:ROSELON_RS13835 ^@ http://purl.uniprot.org/uniprot/W8SRU1 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1294273:ROSELON_RS06305 ^@ http://purl.uniprot.org/uniprot/W8SMF6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1294273:ROSELON_RS00565 ^@ http://purl.uniprot.org/uniprot/W8SJA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1294273:ROSELON_RS07575 ^@ http://purl.uniprot.org/uniprot/W8S5B2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1294273:ROSELON_RS12825 ^@ http://purl.uniprot.org/uniprot/W8S7Y6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1294273:ROSELON_RS12495 ^@ http://purl.uniprot.org/uniprot/W8S7T6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1294273:ROSELON_RS09145 ^@ http://purl.uniprot.org/uniprot/W8S629 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1294273:ROSELON_RS08505 ^@ http://purl.uniprot.org/uniprot/W8RSK5 ^@ Similarity ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family. http://togogenome.org/gene/1294273:ROSELON_RS13650 ^@ http://purl.uniprot.org/uniprot/W8S8C5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS07155 ^@ http://purl.uniprot.org/uniprot/W8RRY8 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1294273:ROSELON_RS08840 ^@ http://purl.uniprot.org/uniprot/W8RSX6 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1294273:ROSELON_RS04410 ^@ http://purl.uniprot.org/uniprot/W8SLC2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1294273:ROSELON_RS10035 ^@ http://purl.uniprot.org/uniprot/W8S6J5 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/1294273:ROSELON_RS05205 ^@ http://purl.uniprot.org/uniprot/W8SLV0 ^@ Function|||Similarity ^@ Belongs to the AcsF family.|||Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME). http://togogenome.org/gene/1294273:ROSELON_RS08115 ^@ http://purl.uniprot.org/uniprot/W8SNI5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1294273:ROSELON_RS00655 ^@ http://purl.uniprot.org/uniprot/W8RXQ1 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/1294273:ROSELON_RS01670 ^@ http://purl.uniprot.org/uniprot/W8S235 ^@ Function ^@ Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. http://togogenome.org/gene/1294273:ROSELON_RS08860 ^@ http://purl.uniprot.org/uniprot/W8S223 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04270 ^@ http://purl.uniprot.org/uniprot/W8RQG6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1294273:ROSELON_RS01680 ^@ http://purl.uniprot.org/uniprot/W8RP56 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS04570 ^@ http://purl.uniprot.org/uniprot/W8RQD5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1294273:ROSELON_RS08315 ^@ http://purl.uniprot.org/uniprot/W8S5M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0283 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13845 ^@ http://purl.uniprot.org/uniprot/W8S4V8 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1294273:ROSELON_RS12885 ^@ http://purl.uniprot.org/uniprot/W8RV36 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1294273:ROSELON_RS14120 ^@ http://purl.uniprot.org/uniprot/W8S8K7 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1294273:ROSELON_RS05420 ^@ http://purl.uniprot.org/uniprot/W8RR43 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS16660 ^@ http://purl.uniprot.org/uniprot/W8S6C8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1294273:ROSELON_RS03985 ^@ http://purl.uniprot.org/uniprot/W8SL41 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1294273:ROSELON_RS16010 ^@ http://purl.uniprot.org/uniprot/W8RWI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS06655 ^@ http://purl.uniprot.org/uniprot/W8S4Q7 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1294273:ROSELON_RS04810 ^@ http://purl.uniprot.org/uniprot/W8RQL4 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1294273:ROSELON_RS07390 ^@ http://purl.uniprot.org/uniprot/W8S1D5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1294273:ROSELON_RS13110 ^@ http://purl.uniprot.org/uniprot/W8S836 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1294273:ROSELON_RS00405 ^@ http://purl.uniprot.org/uniprot/W8S1F0 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1294273:ROSELON_RS07695 ^@ http://purl.uniprot.org/uniprot/W8RS75 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1294273:ROSELON_RS13070 ^@ http://purl.uniprot.org/uniprot/W8RV16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS01080 ^@ http://purl.uniprot.org/uniprot/W8RNG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS11690 ^@ http://purl.uniprot.org/uniprot/W8S7B6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1294273:ROSELON_RS09795 ^@ http://purl.uniprot.org/uniprot/W8S6G7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1294273:ROSELON_RS05160 ^@ http://purl.uniprot.org/uniprot/W8RQR6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ChlB/BchB/BchZ family.|||Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.|||Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits. http://togogenome.org/gene/1294273:ROSELON_RS15595 ^@ http://purl.uniprot.org/uniprot/W8SSV5 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1294273:ROSELON_RS14825 ^@ http://purl.uniprot.org/uniprot/W8RWA5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS16975 ^@ http://purl.uniprot.org/uniprot/W8SA39 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1294273:ROSELON_RS01835 ^@ http://purl.uniprot.org/uniprot/W8RNW9 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1294273:ROSELON_RS12950 ^@ http://purl.uniprot.org/uniprot/W8S806 ^@ Similarity ^@ Belongs to the SHMT family. http://togogenome.org/gene/1294273:ROSELON_RS09685 ^@ http://purl.uniprot.org/uniprot/W8RT97 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1294273:ROSELON_RS05580 ^@ http://purl.uniprot.org/uniprot/W8S0C2 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/1294273:ROSELON_RS03290 ^@ http://purl.uniprot.org/uniprot/W8RZ30 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family.|||Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.|||Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS15105 ^@ http://purl.uniprot.org/uniprot/W8RWE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS05850 ^@ http://purl.uniprot.org/uniprot/W8RRC6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1294273:ROSELON_RS08450 ^@ http://purl.uniprot.org/uniprot/W8RSQ7 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS01150 ^@ http://purl.uniprot.org/uniprot/W8RNX0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS14220 ^@ http://purl.uniprot.org/uniprot/W8S8N0 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1294273:ROSELON_RS04995 ^@ http://purl.uniprot.org/uniprot/W8SLR8 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/1294273:ROSELON_RS13995 ^@ http://purl.uniprot.org/uniprot/W8S8I2 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1294273:ROSELON_RS03745 ^@ http://purl.uniprot.org/uniprot/W8RPV9 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1294273:ROSELON_RS06100 ^@ http://purl.uniprot.org/uniprot/W8SMC0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS13495 ^@ http://purl.uniprot.org/uniprot/W8S4P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1294273:ROSELON_RS00455 ^@ http://purl.uniprot.org/uniprot/W8SJ87 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.|||Cytoplasm|||Homotrimer.|||In the C-terminal section; belongs to the transferase hexapeptide repeat family.|||In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS15295 ^@ http://purl.uniprot.org/uniprot/W8SSQ3 ^@ Similarity ^@ Belongs to the SdhE FAD assembly factor family. http://togogenome.org/gene/1294273:ROSELON_RS04615 ^@ http://purl.uniprot.org/uniprot/W8RQN2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueG family.|||Binds 2 [4Fe-4S] clusters per monomer.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS04420 ^@ http://purl.uniprot.org/uniprot/W8RZP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1294273:ROSELON_RS14410 ^@ http://purl.uniprot.org/uniprot/W8RVQ5 ^@ Function ^@ Multidrug efflux pump. http://togogenome.org/gene/1294273:ROSELON_RS02085 ^@ http://purl.uniprot.org/uniprot/W8RP19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1294273:ROSELON_RS14230 ^@ http://purl.uniprot.org/uniprot/W8S526 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1294273:ROSELON_RS05770 ^@ http://purl.uniprot.org/uniprot/W8SM52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS15875 ^@ http://purl.uniprot.org/uniprot/W8RWS7 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1294273:ROSELON_RS04625 ^@ http://purl.uniprot.org/uniprot/W8SLH0 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1294273:ROSELON_RS14680 ^@ http://purl.uniprot.org/uniprot/W8S5D3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase D family.|||Cytoplasm|||Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides. http://togogenome.org/gene/1294273:ROSELON_RS06970 ^@ http://purl.uniprot.org/uniprot/W8RRX7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1294273:ROSELON_RS04550 ^@ http://purl.uniprot.org/uniprot/W8SLF1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS15525 ^@ http://purl.uniprot.org/uniprot/W8SSU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS05740 ^@ http://purl.uniprot.org/uniprot/W8SM47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS03620 ^@ http://purl.uniprot.org/uniprot/W8RQ52 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1294273:ROSELON_RS08920 ^@ http://purl.uniprot.org/uniprot/W8RST1 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1294273:ROSELON_RS05620 ^@ http://purl.uniprot.org/uniprot/W8SM27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS12500 ^@ http://purl.uniprot.org/uniprot/W8S476 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS05880 ^@ http://purl.uniprot.org/uniprot/W8RR37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1294273:ROSELON_RS13145 ^@ http://purl.uniprot.org/uniprot/W8RV31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS07850 ^@ http://purl.uniprot.org/uniprot/W8S5E7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1294273:ROSELON_RS04030 ^@ http://purl.uniprot.org/uniprot/W8RQ18 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS01110 ^@ http://purl.uniprot.org/uniprot/W8RNH0 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS03870 ^@ http://purl.uniprot.org/uniprot/W8RQ96 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1294273:ROSELON_RS06915 ^@ http://purl.uniprot.org/uniprot/W8RRQ0 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1294273:ROSELON_RS11035 ^@ http://purl.uniprot.org/uniprot/W8SQ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09085 ^@ http://purl.uniprot.org/uniprot/W8RT23 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS15045 ^@ http://purl.uniprot.org/uniprot/W8SSL1 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS13685 ^@ http://purl.uniprot.org/uniprot/W8RVB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS16475 ^@ http://purl.uniprot.org/uniprot/W8RWQ4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/1294273:ROSELON_RS07305 ^@ http://purl.uniprot.org/uniprot/W8SN63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS05215 ^@ http://purl.uniprot.org/uniprot/W8S060 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS11985 ^@ http://purl.uniprot.org/uniprot/W8RUJ6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1294273:ROSELON_RS07345 ^@ http://purl.uniprot.org/uniprot/W8RS79 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1294273:ROSELON_RS15345 ^@ http://purl.uniprot.org/uniprot/W8RWI2 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1294273:ROSELON_RS08235 ^@ http://purl.uniprot.org/uniprot/W8RSG4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1294273:ROSELON_RS14580 ^@ http://purl.uniprot.org/uniprot/W8RVW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1294273:ROSELON_RS07565 ^@ http://purl.uniprot.org/uniprot/W8RS54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1294273:ROSELON_RS12210 ^@ http://purl.uniprot.org/uniprot/W8RUR5 ^@ Function|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Has multiple catalytic activities. Apart from catalyzing the oxidation of (+)-tartrate to oxaloglycolate, also converts meso-tartrate to D-glycerate and catalyzes the oxidative decarboxylation of D-malate to pyruvate. http://togogenome.org/gene/1294273:ROSELON_RS09570 ^@ http://purl.uniprot.org/uniprot/W8S6A5 ^@ Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS07570 ^@ http://purl.uniprot.org/uniprot/W8SNA2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1294273:ROSELON_RS01260 ^@ http://purl.uniprot.org/uniprot/W8RNZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13040 ^@ http://purl.uniprot.org/uniprot/W8S4G9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS12330 ^@ http://purl.uniprot.org/uniprot/W8RUT4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS14135 ^@ http://purl.uniprot.org/uniprot/W8RVS5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS07225 ^@ http://purl.uniprot.org/uniprot/W8RS58 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1294273:ROSELON_RS10795 ^@ http://purl.uniprot.org/uniprot/W8S6V1 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1294273:ROSELON_RS08030 ^@ http://purl.uniprot.org/uniprot/W8S1N5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the histone-like protein H-NS family.|||nucleoid http://togogenome.org/gene/1294273:ROSELON_RS08755 ^@ http://purl.uniprot.org/uniprot/W8RSW0 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1294273:ROSELON_RS12545 ^@ http://purl.uniprot.org/uniprot/W8RUW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS04290 ^@ http://purl.uniprot.org/uniprot/W8RZL2 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1294273:ROSELON_RS06280 ^@ http://purl.uniprot.org/uniprot/W8SMF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1294273:ROSELON_RS00135 ^@ http://purl.uniprot.org/uniprot/W8RN17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09575 ^@ http://purl.uniprot.org/uniprot/W8S2G0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS10140 ^@ http://purl.uniprot.org/uniprot/W8S6K6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS15600 ^@ http://purl.uniprot.org/uniprot/W8S9D9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS16995 ^@ http://purl.uniprot.org/uniprot/W8STN4 ^@ Similarity ^@ In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the malic enzymes family. http://togogenome.org/gene/1294273:ROSELON_RS13105 ^@ http://purl.uniprot.org/uniprot/W8SRF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS04910 ^@ http://purl.uniprot.org/uniprot/W8S010 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1294273:ROSELON_RS07810 ^@ http://purl.uniprot.org/uniprot/W8RSF7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1294273:ROSELON_RS03485 ^@ http://purl.uniprot.org/uniprot/W8SKV2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/1294273:ROSELON_RS06895 ^@ http://purl.uniprot.org/uniprot/W8RRP6 ^@ Similarity ^@ Belongs to the proline racemase family. http://togogenome.org/gene/1294273:ROSELON_RS15280 ^@ http://purl.uniprot.org/uniprot/W8S988 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1294273:ROSELON_RS12070 ^@ http://purl.uniprot.org/uniprot/W8S3Z1 ^@ Function|||Similarity ^@ Belongs to the thioredoxin family. DsbA subfamily.|||May be required for disulfide bond formation in some proteins. http://togogenome.org/gene/1294273:ROSELON_RS11235 ^@ http://purl.uniprot.org/uniprot/W8RU36 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS06685 ^@ http://purl.uniprot.org/uniprot/W8S0X0 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1294273:ROSELON_RS15120 ^@ http://purl.uniprot.org/uniprot/W8S5L9 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1294273:ROSELON_RS10845 ^@ http://purl.uniprot.org/uniprot/W8SQ26 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial microcompartment|||Belongs to the EutB family.|||Binds between the large and small subunits.|||Catalyzes the deamination of various vicinal amino-alcohols to oxo compounds. Allows this organism to utilize ethanolamine as the sole source of nitrogen and carbon in the presence of vitamin B12.|||The basic unit is a heterodimer which dimerizes to form tetramers. The heterotetramers trimerize; 6 large subunits form a core ring with 6 small subunits projecting outwards. http://togogenome.org/gene/1294273:ROSELON_RS07380 ^@ http://purl.uniprot.org/uniprot/W8SN73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1294273:ROSELON_RS00520 ^@ http://purl.uniprot.org/uniprot/W8RNJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1294273:ROSELON_RS09985 ^@ http://purl.uniprot.org/uniprot/W8SPN8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1294273:ROSELON_RS07060 ^@ http://purl.uniprot.org/uniprot/W8S4Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS12755 ^@ http://purl.uniprot.org/uniprot/W8S4C1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1294273:ROSELON_RS05115 ^@ http://purl.uniprot.org/uniprot/W8RQR0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS11155 ^@ http://purl.uniprot.org/uniprot/W8RU22 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1294273:ROSELON_RS04425 ^@ http://purl.uniprot.org/uniprot/W8RQJ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS04920 ^@ http://purl.uniprot.org/uniprot/W8SLQ7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1294273:ROSELON_RS08815 ^@ http://purl.uniprot.org/uniprot/W8SNY0 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1294273:ROSELON_RS11775 ^@ http://purl.uniprot.org/uniprot/W8RUF5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1294273:ROSELON_RS13665 ^@ http://purl.uniprot.org/uniprot/W8RVH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1294273:ROSELON_RS05010 ^@ http://purl.uniprot.org/uniprot/W8RQY2 ^@ Similarity ^@ Belongs to the Tim44 family. http://togogenome.org/gene/1294273:ROSELON_RS09885 ^@ http://purl.uniprot.org/uniprot/W8RTG3 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1294273:ROSELON_RS04725 ^@ http://purl.uniprot.org/uniprot/W8S3T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14165 ^@ http://purl.uniprot.org/uniprot/W8S8M0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS04565 ^@ http://purl.uniprot.org/uniprot/W8RQM1 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1294273:ROSELON_RS01950 ^@ http://purl.uniprot.org/uniprot/W8RYE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14940 ^@ http://purl.uniprot.org/uniprot/W8S5I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1294273:ROSELON_RS01310 ^@ http://purl.uniprot.org/uniprot/W8RNK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15555 ^@ http://purl.uniprot.org/uniprot/W8S5U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the trans-sulfuration enzymes family. MetZ subfamily.|||Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS11200 ^@ http://purl.uniprot.org/uniprot/W8RU28 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS11175 ^@ http://purl.uniprot.org/uniprot/W8S3C8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1294273:ROSELON_RS11570 ^@ http://purl.uniprot.org/uniprot/W8S789 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS03925 ^@ http://purl.uniprot.org/uniprot/W8RPZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07470 ^@ http://purl.uniprot.org/uniprot/W8SN87 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1294273:ROSELON_RS13675 ^@ http://purl.uniprot.org/uniprot/W8S8C9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1294273:ROSELON_RS14415 ^@ http://purl.uniprot.org/uniprot/W8RVZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NiCoT transporter (TC 2.A.52) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14780 ^@ http://purl.uniprot.org/uniprot/W8RW96 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1294273:ROSELON_RS03590 ^@ http://purl.uniprot.org/uniprot/W8RZ81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00935 ^@ http://purl.uniprot.org/uniprot/W8RND7 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1294273:ROSELON_RS11490 ^@ http://purl.uniprot.org/uniprot/W8S769 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS13595 ^@ http://purl.uniprot.org/uniprot/W8S8B8 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1294273:ROSELON_RS15055 ^@ http://purl.uniprot.org/uniprot/W8RW31 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase U32 family. UbiV subfamily.|||Forms an heterodimer with UbiU.|||Required for O(2)-independent ubiquinone (coenzyme Q) biosynthesis. Together with UbiU, is essential for the C6-hydroxylation reaction in the oxygen-independent ubiquinone biosynthesis pathway. http://togogenome.org/gene/1294273:ROSELON_RS01020 ^@ http://purl.uniprot.org/uniprot/W8S1R6 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1294273:ROSELON_RS08645 ^@ http://purl.uniprot.org/uniprot/W8SNU0 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1294273:ROSELON_RS02300 ^@ http://purl.uniprot.org/uniprot/W8S2I8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1294273:ROSELON_RS13605 ^@ http://purl.uniprot.org/uniprot/W8RVA2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS12650 ^@ http://purl.uniprot.org/uniprot/W8SR69 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1294273:ROSELON_RS07665 ^@ http://purl.uniprot.org/uniprot/W8S1H4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1294273:ROSELON_RS02705 ^@ http://purl.uniprot.org/uniprot/W8RPE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09215 ^@ http://purl.uniprot.org/uniprot/W8RSY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS03765 ^@ http://purl.uniprot.org/uniprot/W8RZB2 ^@ Subcellular Location Annotation ^@ chloroplast http://togogenome.org/gene/1294273:ROSELON_RS05800 ^@ http://purl.uniprot.org/uniprot/W8S4B0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00675 ^@ http://purl.uniprot.org/uniprot/W8S1J4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YciB family.|||Cell inner membrane|||Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis. http://togogenome.org/gene/1294273:ROSELON_RS05455 ^@ http://purl.uniprot.org/uniprot/W8S443 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS07490 ^@ http://purl.uniprot.org/uniprot/W8RS41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP12 family.|||Mitochondrion http://togogenome.org/gene/1294273:ROSELON_RS17030 ^@ http://purl.uniprot.org/uniprot/W8S6I6 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS04905 ^@ http://purl.uniprot.org/uniprot/W8S3V6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1294273:ROSELON_RS09020 ^@ http://purl.uniprot.org/uniprot/W8RSU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS07370 ^@ http://purl.uniprot.org/uniprot/W8RS82 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1294273:ROSELON_RS00495 ^@ http://purl.uniprot.org/uniprot/W8RXM5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS08915 ^@ http://purl.uniprot.org/uniprot/W8RSY8 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1294273:ROSELON_RS01040 ^@ http://purl.uniprot.org/uniprot/W8SJJ7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS12075 ^@ http://purl.uniprot.org/uniprot/W8RUL5 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS08525 ^@ http://purl.uniprot.org/uniprot/W8RSS3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1294273:ROSELON_RS12935 ^@ http://purl.uniprot.org/uniprot/W8RUZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS05235 ^@ http://purl.uniprot.org/uniprot/W8S405 ^@ Function|||Similarity ^@ Belongs to the Mg-chelatase subunits D/I family.|||Involved in bacteriochlorophyll biosynthesis; introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. http://togogenome.org/gene/1294273:ROSELON_RS08105 ^@ http://purl.uniprot.org/uniprot/W8RSJ9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1294273:ROSELON_RS06110 ^@ http://purl.uniprot.org/uniprot/W8S0L4 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1294273:ROSELON_RS01025 ^@ http://purl.uniprot.org/uniprot/W8RXW9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS01140 ^@ http://purl.uniprot.org/uniprot/W8S1T9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS03430 ^@ http://purl.uniprot.org/uniprot/W8SKU9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS05995 ^@ http://purl.uniprot.org/uniprot/W8S0J6 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1294273:ROSELON_RS09535 ^@ http://purl.uniprot.org/uniprot/W8RT98 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1294273:ROSELON_RS12405 ^@ http://purl.uniprot.org/uniprot/W8SR31 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1294273:ROSELON_RS16740 ^@ http://purl.uniprot.org/uniprot/W8S6D7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS10910 ^@ http://purl.uniprot.org/uniprot/W8RTW8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS16915 ^@ http://purl.uniprot.org/uniprot/W8RWZ1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1294273:ROSELON_RS09945 ^@ http://purl.uniprot.org/uniprot/W8RTH0 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1294273:ROSELON_RS12910 ^@ http://purl.uniprot.org/uniprot/W8RV41 ^@ Similarity ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1294273:ROSELON_RS06500 ^@ http://purl.uniprot.org/uniprot/W8RRG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1294273:ROSELON_RS09060 ^@ http://purl.uniprot.org/uniprot/W8S262 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1294273:ROSELON_RS13185 ^@ http://purl.uniprot.org/uniprot/W8RV38 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1294273:ROSELON_RS14920 ^@ http://purl.uniprot.org/uniprot/W8RW12 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS09340 ^@ http://purl.uniprot.org/uniprot/W8S659 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS12050 ^@ http://purl.uniprot.org/uniprot/W8S3W0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1294273:ROSELON_RS05285 ^@ http://purl.uniprot.org/uniprot/W8S073 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/1294273:ROSELON_RS11350 ^@ http://purl.uniprot.org/uniprot/W8S734 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS13075 ^@ http://purl.uniprot.org/uniprot/W8RV74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS01575 ^@ http://purl.uniprot.org/uniprot/W8S213 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10700 ^@ http://purl.uniprot.org/uniprot/W8SQ04 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS09970 ^@ http://purl.uniprot.org/uniprot/W8S2R1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15015 ^@ http://purl.uniprot.org/uniprot/W8RWD6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1294273:ROSELON_RS07765 ^@ http://purl.uniprot.org/uniprot/W8RS88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS05270 ^@ http://purl.uniprot.org/uniprot/W8RR20 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1294273:ROSELON_RS17090 ^@ http://purl.uniprot.org/uniprot/W8S6K8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS08510 ^@ http://purl.uniprot.org/uniprot/W8SNR4 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/1294273:ROSELON_RS02315 ^@ http://purl.uniprot.org/uniprot/W8RP86 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS13015 ^@ http://purl.uniprot.org/uniprot/W8S4G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS12955 ^@ http://purl.uniprot.org/uniprot/W8S4F4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1294273:ROSELON_RS09165 ^@ http://purl.uniprot.org/uniprot/W8SP55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS10215 ^@ http://purl.uniprot.org/uniprot/W8S2W0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00770 ^@ http://purl.uniprot.org/uniprot/W8RNA9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS04785 ^@ http://purl.uniprot.org/uniprot/W8RQL0 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1294273:ROSELON_RS01855 ^@ http://purl.uniprot.org/uniprot/W8RPA1 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1294273:ROSELON_RS08305 ^@ http://purl.uniprot.org/uniprot/W8RSH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS06690 ^@ http://purl.uniprot.org/uniprot/W8RRS3 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1294273:ROSELON_RS14215 ^@ http://purl.uniprot.org/uniprot/W8SS18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS05730 ^@ http://purl.uniprot.org/uniprot/W8RRA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS10780 ^@ http://purl.uniprot.org/uniprot/W8S358 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1294273:ROSELON_RS04210 ^@ http://purl.uniprot.org/uniprot/W8RZJ7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b family.|||Binds 2 heme groups non-covalently.|||Cell membrane|||Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.|||Membrane|||The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein. http://togogenome.org/gene/1294273:ROSELON_RS08685 ^@ http://purl.uniprot.org/uniprot/W8RSU9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS14490 ^@ http://purl.uniprot.org/uniprot/W8RW11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1294273:ROSELON_RS02495 ^@ http://purl.uniprot.org/uniprot/W8S2L8 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/1294273:ROSELON_RS07140 ^@ http://purl.uniprot.org/uniprot/W8S530 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS12150 ^@ http://purl.uniprot.org/uniprot/W8S428 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1294273:ROSELON_RS04605 ^@ http://purl.uniprot.org/uniprot/W8S3P4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 51 family.|||Cell inner membrane|||Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. http://togogenome.org/gene/1294273:ROSELON_RS02965 ^@ http://purl.uniprot.org/uniprot/W8SKM0 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS12205 ^@ http://purl.uniprot.org/uniprot/W8RUN1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS04575 ^@ http://purl.uniprot.org/uniprot/W8SLF6 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1294273:ROSELON_RS13670 ^@ http://purl.uniprot.org/uniprot/W8SRQ4 ^@ Function ^@ This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited. http://togogenome.org/gene/1294273:ROSELON_RS06905 ^@ http://purl.uniprot.org/uniprot/W8S4V9 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1294273:ROSELON_RS03015 ^@ http://purl.uniprot.org/uniprot/W8RPI4 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1294273:ROSELON_RS13425 ^@ http://purl.uniprot.org/uniprot/W8SRL1 ^@ PTM ^@ Binds 1 heme group per subunit. http://togogenome.org/gene/1294273:ROSELON_RS15180 ^@ http://purl.uniprot.org/uniprot/W8S976 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09150 ^@ http://purl.uniprot.org/uniprot/W8S281 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1294273:ROSELON_RS14305 ^@ http://purl.uniprot.org/uniprot/W8S539 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS02735 ^@ http://purl.uniprot.org/uniprot/W8SKI7 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS05105 ^@ http://purl.uniprot.org/uniprot/W8S039 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the reaction center PufL/M/PsbA/D family.|||Cellular chromatophore membrane|||Membrane|||Reaction center is composed of four bacteriochlorophylls, two bacteriopheophytins, two ubiquinones, one iron, and highly hydrophobic polypeptide chains.|||The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS01285 ^@ http://purl.uniprot.org/uniprot/W8RP00 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS08600 ^@ http://purl.uniprot.org/uniprot/W8S1Y3 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1294273:ROSELON_RS06720 ^@ http://purl.uniprot.org/uniprot/W8RRS8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1294273:ROSELON_RS13590 ^@ http://purl.uniprot.org/uniprot/W8SRN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1294273:ROSELON_RS05660 ^@ http://purl.uniprot.org/uniprot/W8RR90 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1294273:ROSELON_RS04635 ^@ http://purl.uniprot.org/uniprot/W8RZU7 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1294273:ROSELON_RS05875 ^@ http://purl.uniprot.org/uniprot/W8RRD1 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS13975 ^@ http://purl.uniprot.org/uniprot/W8S4Y3 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1294273:ROSELON_RS06090 ^@ http://purl.uniprot.org/uniprot/W8S0L1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1294273:ROSELON_RS00925 ^@ http://purl.uniprot.org/uniprot/W8RXV3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS00590 ^@ http://purl.uniprot.org/uniprot/W8SJB0 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS03890 ^@ http://purl.uniprot.org/uniprot/W8RZD6 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1294273:ROSELON_RS15920 ^@ http://purl.uniprot.org/uniprot/W8ST28 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/1294273:ROSELON_RS12895 ^@ http://purl.uniprot.org/uniprot/W8S7Z8 ^@ Function|||Similarity ^@ Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.|||Belongs to the Nudix hydrolase family. NudF subfamily. http://togogenome.org/gene/1294273:ROSELON_RS08855 ^@ http://purl.uniprot.org/uniprot/W8S5X8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS07445 ^@ http://purl.uniprot.org/uniprot/W8RS35 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1294273:ROSELON_RS03275 ^@ http://purl.uniprot.org/uniprot/W8RPM3 ^@ Function|||Similarity ^@ Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). http://togogenome.org/gene/1294273:ROSELON_RS05120 ^@ http://purl.uniprot.org/uniprot/W8SLT6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS14020 ^@ http://purl.uniprot.org/uniprot/W8S8I6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1294273:ROSELON_RS00960 ^@ http://purl.uniprot.org/uniprot/W8RNE4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS08190 ^@ http://purl.uniprot.org/uniprot/W8SNJ8 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS11865 ^@ http://purl.uniprot.org/uniprot/W8S7F3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS00790 ^@ http://purl.uniprot.org/uniprot/W8RNB3 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS01220 ^@ http://purl.uniprot.org/uniprot/W8RNY3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS11245 ^@ http://purl.uniprot.org/uniprot/W8SQB0 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1294273:ROSELON_RS06595 ^@ http://purl.uniprot.org/uniprot/W8S0U9 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/1294273:ROSELON_RS14850 ^@ http://purl.uniprot.org/uniprot/W8RWA9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS09695 ^@ http://purl.uniprot.org/uniprot/W8S6F5 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1294273:ROSELON_RS11535 ^@ http://purl.uniprot.org/uniprot/W8RU95 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/1294273:ROSELON_RS00175 ^@ http://purl.uniprot.org/uniprot/W8RN23 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS12780 ^@ http://purl.uniprot.org/uniprot/W8S4C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS04235 ^@ http://purl.uniprot.org/uniprot/W8RZK2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1294273:ROSELON_RS04230 ^@ http://purl.uniprot.org/uniprot/W8S3G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS04380 ^@ http://purl.uniprot.org/uniprot/W8RQ89 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1294273:ROSELON_RS07030 ^@ http://purl.uniprot.org/uniprot/W8SMY2 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1294273:ROSELON_RS03630 ^@ http://purl.uniprot.org/uniprot/W8SKX8 ^@ Subunit ^@ Monomer. http://togogenome.org/gene/1294273:ROSELON_RS17005 ^@ http://purl.uniprot.org/uniprot/W8S6I2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS04945 ^@ http://purl.uniprot.org/uniprot/W8SLR1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1294273:ROSELON_RS08935 ^@ http://purl.uniprot.org/uniprot/W8S237 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1294273:ROSELON_RS15255 ^@ http://purl.uniprot.org/uniprot/W8SSP1 ^@ Similarity ^@ Belongs to the DDAH family. http://togogenome.org/gene/1294273:ROSELON_RS07240 ^@ http://purl.uniprot.org/uniprot/W8S556 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1294273:ROSELON_RS04545 ^@ http://purl.uniprot.org/uniprot/W8RQC9 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. http://togogenome.org/gene/1294273:ROSELON_RS08295 ^@ http://purl.uniprot.org/uniprot/W8S1T2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS00640 ^@ http://purl.uniprot.org/uniprot/W8RN86 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1294273:ROSELON_RS04940 ^@ http://purl.uniprot.org/uniprot/W8RQN5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1294273:ROSELON_RS11540 ^@ http://purl.uniprot.org/uniprot/W8SQH7 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1294273:ROSELON_RS03840 ^@ http://purl.uniprot.org/uniprot/W8RQ91 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1294273:ROSELON_RS08255 ^@ http://purl.uniprot.org/uniprot/W8RSG9 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07435 ^@ http://purl.uniprot.org/uniprot/W8S590 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS11620 ^@ http://purl.uniprot.org/uniprot/W8S3N3 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS01485 ^@ http://purl.uniprot.org/uniprot/W8RY47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04000 ^@ http://purl.uniprot.org/uniprot/W8RQB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS10940 ^@ http://purl.uniprot.org/uniprot/W8S6X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1294273:ROSELON_RS06315 ^@ http://purl.uniprot.org/uniprot/W8S0Q0 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1294273:ROSELON_RS13400 ^@ http://purl.uniprot.org/uniprot/W8S889 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS08590 ^@ http://purl.uniprot.org/uniprot/W8SNT1 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1294273:ROSELON_RS15770 ^@ http://purl.uniprot.org/uniprot/W8RWE1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS16850 ^@ http://purl.uniprot.org/uniprot/W8STK0 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1294273:ROSELON_RS06535 ^@ http://purl.uniprot.org/uniprot/W8S4N6 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1294273:ROSELON_RS13240 ^@ http://purl.uniprot.org/uniprot/W8SRH6 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1294273:ROSELON_RS03165 ^@ http://purl.uniprot.org/uniprot/W8SKQ2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1294273:ROSELON_RS14095 ^@ http://purl.uniprot.org/uniprot/W8S8K3 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1294273:ROSELON_RS15285 ^@ http://purl.uniprot.org/uniprot/W8RW59 ^@ Similarity ^@ Belongs to the thioredoxin family. DsbE subfamily. http://togogenome.org/gene/1294273:ROSELON_RS00485 ^@ http://purl.uniprot.org/uniprot/W8SJ91 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1294273:ROSELON_RS07710 ^@ http://purl.uniprot.org/uniprot/W8RSE3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS07970 ^@ http://purl.uniprot.org/uniprot/W8RSC2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS14295 ^@ http://purl.uniprot.org/uniprot/W8SS36 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1294273:ROSELON_RS01165 ^@ http://purl.uniprot.org/uniprot/W8S1U3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/1294273:ROSELON_RS09815 ^@ http://purl.uniprot.org/uniprot/W8SPL2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1294273:ROSELON_RS06815 ^@ http://purl.uniprot.org/uniprot/W8RRU7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1294273:ROSELON_RS08205 ^@ http://purl.uniprot.org/uniprot/W8RSL3 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1294273:ROSELON_RS16240 ^@ http://purl.uniprot.org/uniprot/W8S9Q2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Probably responsible for the translocation of the substrate across the membrane.|||Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.|||The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB). http://togogenome.org/gene/1294273:ROSELON_RS16970 ^@ http://purl.uniprot.org/uniprot/W8STM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer.|||The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. http://togogenome.org/gene/1294273:ROSELON_RS00930 ^@ http://purl.uniprot.org/uniprot/W8RNS4 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1294273:ROSELON_RS01200 ^@ http://purl.uniprot.org/uniprot/W8RNX8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS12790 ^@ http://purl.uniprot.org/uniprot/W8RV14 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1294273:ROSELON_RS01530 ^@ http://purl.uniprot.org/uniprot/W8SJT9 ^@ Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. http://togogenome.org/gene/1294273:ROSELON_RS05135 ^@ http://purl.uniprot.org/uniprot/W8RR02 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS12035 ^@ http://purl.uniprot.org/uniprot/W8RUK7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1294273:ROSELON_RS04440 ^@ http://purl.uniprot.org/uniprot/W8RZQ0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS06190 ^@ http://purl.uniprot.org/uniprot/W8RRJ6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1294273:ROSELON_RS12180 ^@ http://purl.uniprot.org/uniprot/W8RUR2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1294273:ROSELON_RS02660 ^@ http://purl.uniprot.org/uniprot/W8RPD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14990 ^@ http://purl.uniprot.org/uniprot/W8RW22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes.|||Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS08680 ^@ http://purl.uniprot.org/uniprot/W8S1Z5 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this 1-Cys peroxiredoxin, no C(R) is present and C(P) instead forms a disulfide with a cysteine from another protein or with a small thiol molecule.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1294273:ROSELON_RS07395 ^@ http://purl.uniprot.org/uniprot/W8RS86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1294273:ROSELON_RS00995 ^@ http://purl.uniprot.org/uniprot/W8S1R1 ^@ Function|||Similarity ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. http://togogenome.org/gene/1294273:ROSELON_RS03425 ^@ http://purl.uniprot.org/uniprot/W8RPP7 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS15160 ^@ http://purl.uniprot.org/uniprot/W8RW42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS10500 ^@ http://purl.uniprot.org/uniprot/W8RTN4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00065 ^@ http://purl.uniprot.org/uniprot/W8SJ21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS08125 ^@ http://purl.uniprot.org/uniprot/W8S1Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).|||Homodimer. Part of the 2-oxoglutarate dehydrogenase (OGDH) complex composed of E1 (2-oxoglutarate dehydrogenase), E2 (dihydrolipoamide succinyltransferase) and E3 (dihydrolipoamide dehydrogenase); the complex contains multiple copies of the three enzymatic components (E1, E2 and E3). http://togogenome.org/gene/1294273:ROSELON_RS07475 ^@ http://purl.uniprot.org/uniprot/W8S598 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS06145 ^@ http://purl.uniprot.org/uniprot/W8RR89 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1294273:ROSELON_RS16115 ^@ http://purl.uniprot.org/uniprot/W8RWK0 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS01170 ^@ http://purl.uniprot.org/uniprot/W8RXZ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1294273:ROSELON_RS12610 ^@ http://purl.uniprot.org/uniprot/W8S7V5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1294273:ROSELON_RS14615 ^@ http://purl.uniprot.org/uniprot/W8RW63 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. http://togogenome.org/gene/1294273:ROSELON_RS12710 ^@ http://purl.uniprot.org/uniprot/W8S4B1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the COX15/CtaA family. Type 2 subfamily.|||Catalyzes the conversion of heme O to heme A by two successive hydroxylations of the methyl group at C8. The first hydroxylation forms heme I, the second hydroxylation results in an unstable dihydroxymethyl group, which spontaneously dehydrates, resulting in the formyl group of heme A.|||Cell membrane|||Interacts with CtaB.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS16815 ^@ http://purl.uniprot.org/uniprot/W8S6E7 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1294273:ROSELON_RS11675 ^@ http://purl.uniprot.org/uniprot/W8RUB3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS12670 ^@ http://purl.uniprot.org/uniprot/W8RUV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1294273:ROSELON_RS03185 ^@ http://purl.uniprot.org/uniprot/W8RPK9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS03510 ^@ http://purl.uniprot.org/uniprot/W8RZ67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK. http://togogenome.org/gene/1294273:ROSELON_RS02405 ^@ http://purl.uniprot.org/uniprot/W8RPA0 ^@ Similarity ^@ Belongs to the MreC family. http://togogenome.org/gene/1294273:ROSELON_RS07375 ^@ http://purl.uniprot.org/uniprot/W8RS24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS13765 ^@ http://purl.uniprot.org/uniprot/W8SRS5 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1294273:ROSELON_RS15035 ^@ http://purl.uniprot.org/uniprot/W8RW28 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS16230 ^@ http://purl.uniprot.org/uniprot/W8RX00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS09275 ^@ http://purl.uniprot.org/uniprot/W8SP74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS13390 ^@ http://purl.uniprot.org/uniprot/W8RV72 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS17050 ^@ http://purl.uniprot.org/uniprot/W8STP6 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1294273:ROSELON_RS06300 ^@ http://purl.uniprot.org/uniprot/W8RRB9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1294273:ROSELON_RS16965 ^@ http://purl.uniprot.org/uniprot/W8RXE4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1294273:ROSELON_RS03970 ^@ http://purl.uniprot.org/uniprot/W8RZF2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1294273:ROSELON_RS09075 ^@ http://purl.uniprot.org/uniprot/W8S614 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1294273:ROSELON_RS07385 ^@ http://purl.uniprot.org/uniprot/W8S583 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS06475 ^@ http://purl.uniprot.org/uniprot/W8RRN9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1294273:ROSELON_RS05885 ^@ http://purl.uniprot.org/uniprot/W8SM73 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1294273:ROSELON_RS01815 ^@ http://purl.uniprot.org/uniprot/W8RNW3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS12360 ^@ http://purl.uniprot.org/uniprot/W8S7R6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS13945 ^@ http://purl.uniprot.org/uniprot/W8S4X8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS03385 ^@ http://purl.uniprot.org/uniprot/W8SKT6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07585 ^@ http://purl.uniprot.org/uniprot/W8RSC0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07875 ^@ http://purl.uniprot.org/uniprot/W8S5E9 ^@ Function|||Similarity ^@ A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex.|||Belongs to the bacterial AtpI family. http://togogenome.org/gene/1294273:ROSELON_RS03315 ^@ http://purl.uniprot.org/uniprot/W8RZ35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13755 ^@ http://purl.uniprot.org/uniprot/W8RVC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1294273:ROSELON_RS03800 ^@ http://purl.uniprot.org/uniprot/W8SL09 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1294273:ROSELON_RS12395 ^@ http://purl.uniprot.org/uniprot/W8RUQ8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS07090 ^@ http://purl.uniprot.org/uniprot/W8S158 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00350 ^@ http://purl.uniprot.org/uniprot/W8SJ70 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1294273:ROSELON_RS01230 ^@ http://purl.uniprot.org/uniprot/W8SJM9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1294273:ROSELON_RS10635 ^@ http://purl.uniprot.org/uniprot/W8RTR0 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1294273:ROSELON_RS05895 ^@ http://purl.uniprot.org/uniprot/W8S0H8 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1294273:ROSELON_RS07895 ^@ http://purl.uniprot.org/uniprot/W8SNF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07415 ^@ http://purl.uniprot.org/uniprot/W8S1D9 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1294273:ROSELON_RS01900 ^@ http://purl.uniprot.org/uniprot/W8RYD8 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS15855 ^@ http://purl.uniprot.org/uniprot/W8ST13 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1294273:ROSELON_RS00050 ^@ http://purl.uniprot.org/uniprot/W8RXF4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS03090 ^@ http://purl.uniprot.org/uniprot/W8RPJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS10735 ^@ http://purl.uniprot.org/uniprot/W8RTU8 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1294273:ROSELON_RS08785 ^@ http://purl.uniprot.org/uniprot/W8RSQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS07260 ^@ http://purl.uniprot.org/uniprot/W8SN56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1294273:ROSELON_RS02350 ^@ http://purl.uniprot.org/uniprot/W8RYN3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1294273:ROSELON_RS03235 ^@ http://purl.uniprot.org/uniprot/W8S2Z1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1294273:ROSELON_RS11785 ^@ http://purl.uniprot.org/uniprot/W8S7D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS02610 ^@ http://purl.uniprot.org/uniprot/W8RPD2 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS01300 ^@ http://purl.uniprot.org/uniprot/W8RY14 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1294273:ROSELON_RS02585 ^@ http://purl.uniprot.org/uniprot/W8RPC7 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1294273:ROSELON_RS02895 ^@ http://purl.uniprot.org/uniprot/W8RPH0 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1294273:ROSELON_RS06290 ^@ http://purl.uniprot.org/uniprot/W8S0P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1294273:ROSELON_RS17085 ^@ http://purl.uniprot.org/uniprot/W8SA78 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS07310 ^@ http://purl.uniprot.org/uniprot/W8S549 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS00130 ^@ http://purl.uniprot.org/uniprot/W8RNC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09335 ^@ http://purl.uniprot.org/uniprot/W8SP89 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1294273:ROSELON_RS17040 ^@ http://purl.uniprot.org/uniprot/W8RXG2 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1294273:ROSELON_RS11325 ^@ http://purl.uniprot.org/uniprot/W8S731 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1294273:ROSELON_RS03910 ^@ http://purl.uniprot.org/uniprot/W8S3A6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10480 ^@ http://purl.uniprot.org/uniprot/W8SPW7 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1294273:ROSELON_RS10330 ^@ http://purl.uniprot.org/uniprot/W8RTK0 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1294273:ROSELON_RS05130 ^@ http://purl.uniprot.org/uniprot/W8S044 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PucC family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00435 ^@ http://purl.uniprot.org/uniprot/W8S1F4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15720 ^@ http://purl.uniprot.org/uniprot/W8RWD4 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS04470 ^@ http://purl.uniprot.org/uniprot/W8RQB2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BPG-independent phosphoglycerate mutase family.|||Binds 2 manganese ions per subunit.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS06120 ^@ http://purl.uniprot.org/uniprot/W8RR83 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1294273:ROSELON_RS07425 ^@ http://purl.uniprot.org/uniprot/W8RS32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS02460 ^@ http://purl.uniprot.org/uniprot/W8SKE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS02090 ^@ http://purl.uniprot.org/uniprot/W8SK59 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS03010 ^@ http://purl.uniprot.org/uniprot/W8RPW0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14930 ^@ http://purl.uniprot.org/uniprot/W8SSJ2 ^@ Similarity ^@ Belongs to the PpiC/parvulin rotamase family. http://togogenome.org/gene/1294273:ROSELON_RS13475 ^@ http://purl.uniprot.org/uniprot/W8SRM0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS04845 ^@ http://purl.uniprot.org/uniprot/W8SLP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1294273:ROSELON_RS16785 ^@ http://purl.uniprot.org/uniprot/W8STI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1294273:ROSELON_RS11520 ^@ http://purl.uniprot.org/uniprot/W8S3L2 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1294273:ROSELON_RS11125 ^@ http://purl.uniprot.org/uniprot/W8S3B8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1294273:ROSELON_RS07265 ^@ http://purl.uniprot.org/uniprot/W8S561 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1294273:ROSELON_RS16910 ^@ http://purl.uniprot.org/uniprot/W8S6G5 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1294273:ROSELON_RS12345 ^@ http://purl.uniprot.org/uniprot/W8S454 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS05110 ^@ http://purl.uniprot.org/uniprot/W8RQZ9 ^@ Function|||PTM ^@ Binds 4 heme groups per subunit.|||The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor. http://togogenome.org/gene/1294273:ROSELON_RS06170 ^@ http://purl.uniprot.org/uniprot/W8RR94 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1294273:ROSELON_RS15805 ^@ http://purl.uniprot.org/uniprot/W8ST02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1294273:ROSELON_RS03730 ^@ http://purl.uniprot.org/uniprot/W8S372 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1294273:ROSELON_RS13990 ^@ http://purl.uniprot.org/uniprot/W8SRX4 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1294273:ROSELON_RS10370 ^@ http://purl.uniprot.org/uniprot/W8S2Y5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS09070 ^@ http://purl.uniprot.org/uniprot/W8SP32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15800 ^@ http://purl.uniprot.org/uniprot/W8RWR2 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1294273:ROSELON_RS06750 ^@ http://purl.uniprot.org/uniprot/W8RRL5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1294273:ROSELON_RS09080 ^@ http://purl.uniprot.org/uniprot/W8S266 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1294273:ROSELON_RS08055 ^@ http://purl.uniprot.org/uniprot/W8S1P0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.|||Binds 1 [2Fe-2S] cluster.|||Binds 1 [3Fe-4S] cluster.|||Binds 1 [4Fe-4S] cluster.|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur, cytochrome b-556, and a hydrophobic anchor protein. http://togogenome.org/gene/1294273:ROSELON_RS08720 ^@ http://purl.uniprot.org/uniprot/W8S5V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1294273:ROSELON_RS16655 ^@ http://purl.uniprot.org/uniprot/W8S9W4 ^@ Function|||Similarity ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia. http://togogenome.org/gene/1294273:ROSELON_RS16095 ^@ http://purl.uniprot.org/uniprot/W8RWX3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1294273:ROSELON_RS16105 ^@ http://purl.uniprot.org/uniprot/W8S9N2 ^@ Function ^@ Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. http://togogenome.org/gene/1294273:ROSELON_RS14545 ^@ http://purl.uniprot.org/uniprot/W8SS93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/1294273:ROSELON_RS04280 ^@ http://purl.uniprot.org/uniprot/W8SL97 ^@ Function ^@ Acts on leucine, isoleucine and valine. http://togogenome.org/gene/1294273:ROSELON_RS06575 ^@ http://purl.uniprot.org/uniprot/W8RRQ5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1294273:ROSELON_RS08110 ^@ http://purl.uniprot.org/uniprot/W8RSE6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1294273:ROSELON_RS01440 ^@ http://purl.uniprot.org/uniprot/W8RY38 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1294273:ROSELON_RS06080 ^@ http://purl.uniprot.org/uniprot/W8SMB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1294273:ROSELON_RS05445 ^@ http://purl.uniprot.org/uniprot/W8RQW4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1294273:ROSELON_RS07300 ^@ http://purl.uniprot.org/uniprot/W8RS17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1294273:ROSELON_RS04665 ^@ http://purl.uniprot.org/uniprot/W8RQG0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1294273:ROSELON_RS15540 ^@ http://purl.uniprot.org/uniprot/W8RWM0 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/1294273:ROSELON_RS10290 ^@ http://purl.uniprot.org/uniprot/W8S6M8 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS04500 ^@ http://purl.uniprot.org/uniprot/W8SLE0 ^@ Function|||Similarity ^@ Belongs to the methyltransferase superfamily. UbiG/COQ3 family.|||O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. http://togogenome.org/gene/1294273:ROSELON_RS03025 ^@ http://purl.uniprot.org/uniprot/W8S2V8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS07420 ^@ http://purl.uniprot.org/uniprot/W8RS91 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS02655 ^@ http://purl.uniprot.org/uniprot/W8RPQ7 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS12605 ^@ http://purl.uniprot.org/uniprot/W8SR61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1294273:ROSELON_RS06225 ^@ http://purl.uniprot.org/uniprot/W8RRA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10135 ^@ http://purl.uniprot.org/uniprot/W8SPR5 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1294273:ROSELON_RS15700 ^@ http://purl.uniprot.org/uniprot/W8RWD0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS05000 ^@ http://purl.uniprot.org/uniprot/W8S3W8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecB family.|||Cytoplasm|||Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.|||One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. http://togogenome.org/gene/1294273:ROSELON_RS00075 ^@ http://purl.uniprot.org/uniprot/W8RXF8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS03555 ^@ http://purl.uniprot.org/uniprot/W8SKW5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1294273:ROSELON_RS04800 ^@ http://purl.uniprot.org/uniprot/W8RZZ7 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS05050 ^@ http://purl.uniprot.org/uniprot/W8S3X6 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/1294273:ROSELON_RS16390 ^@ http://purl.uniprot.org/uniprot/W8RWP2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1294273:ROSELON_RS00710 ^@ http://purl.uniprot.org/uniprot/W8SJC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1294273:ROSELON_RS07200 ^@ http://purl.uniprot.org/uniprot/W8RS52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS00100 ^@ http://purl.uniprot.org/uniprot/W8RXG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS13320 ^@ http://purl.uniprot.org/uniprot/W8S876 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1294273:ROSELON_RS00965 ^@ http://purl.uniprot.org/uniprot/W8SJI4 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/1294273:ROSELON_RS04510 ^@ http://purl.uniprot.org/uniprot/W8RZR9 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1294273:ROSELON_RS14560 ^@ http://purl.uniprot.org/uniprot/W8RVU8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 7 family.|||Homodimer.|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS10165 ^@ http://purl.uniprot.org/uniprot/W8S6K9 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS13020 ^@ http://purl.uniprot.org/uniprot/W8RV07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00900 ^@ http://purl.uniprot.org/uniprot/W8RXU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 30 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS06165 ^@ http://purl.uniprot.org/uniprot/W8RRJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS07075 ^@ http://purl.uniprot.org/uniprot/W8RRT8 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1294273:ROSELON_RS03810 ^@ http://purl.uniprot.org/uniprot/W8RZC2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS13435 ^@ http://purl.uniprot.org/uniprot/W8S4N3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS09495 ^@ http://purl.uniprot.org/uniprot/W8S692 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14375 ^@ http://purl.uniprot.org/uniprot/W8S8R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS11425 ^@ http://purl.uniprot.org/uniprot/W8SQE8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS07025 ^@ http://purl.uniprot.org/uniprot/W8RRS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1294273:ROSELON_RS11695 ^@ http://purl.uniprot.org/uniprot/W8S3P5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1294273:ROSELON_RS07010 ^@ http://purl.uniprot.org/uniprot/W8S4Y5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS01690 ^@ http://purl.uniprot.org/uniprot/W8SJX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04960 ^@ http://purl.uniprot.org/uniprot/W8RQX3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1294273:ROSELON_RS03815 ^@ http://purl.uniprot.org/uniprot/W8RQ86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1294273:ROSELON_RS16520 ^@ http://purl.uniprot.org/uniprot/W8STC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1294273:ROSELON_RS00660 ^@ http://purl.uniprot.org/uniprot/W8RNL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS07160 ^@ http://purl.uniprot.org/uniprot/W8SN39 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS03040 ^@ http://purl.uniprot.org/uniprot/W8RPI6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS15480 ^@ http://purl.uniprot.org/uniprot/W8S9C3 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1294273:ROSELON_RS14895 ^@ http://purl.uniprot.org/uniprot/W8RW09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS11595 ^@ http://purl.uniprot.org/uniprot/W8S3M7 ^@ Similarity|||Subunit ^@ Belongs to the transketolase family.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS09755 ^@ http://purl.uniprot.org/uniprot/W8RTB0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS05030 ^@ http://purl.uniprot.org/uniprot/W8S028 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS13740 ^@ http://purl.uniprot.org/uniprot/W8SRR9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS02645 ^@ http://purl.uniprot.org/uniprot/W8S2P6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07355 ^@ http://purl.uniprot.org/uniprot/W8SN70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS10235 ^@ http://purl.uniprot.org/uniprot/W8S6M1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS17620 ^@ http://purl.uniprot.org/uniprot/W8RWQ2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1294273:ROSELON_RS13935 ^@ http://purl.uniprot.org/uniprot/W8SRW3 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS04985 ^@ http://purl.uniprot.org/uniprot/W8RQX7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). http://togogenome.org/gene/1294273:ROSELON_RS06550 ^@ http://purl.uniprot.org/uniprot/W8RRQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS06105 ^@ http://purl.uniprot.org/uniprot/W8S4G6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS14160 ^@ http://purl.uniprot.org/uniprot/W8RVT0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1294273:ROSELON_RS06765 ^@ http://purl.uniprot.org/uniprot/W8S0Y6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS15455 ^@ http://purl.uniprot.org/uniprot/W8S9B9 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1294273:ROSELON_RS12550 ^@ http://purl.uniprot.org/uniprot/W8SR50 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS00095 ^@ http://purl.uniprot.org/uniprot/W8S198 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1294273:ROSELON_RS00155 ^@ http://purl.uniprot.org/uniprot/W8RN19 ^@ Similarity ^@ Belongs to the trimethylamine methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07885 ^@ http://purl.uniprot.org/uniprot/W8RSG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00890 ^@ http://purl.uniprot.org/uniprot/W8SJG7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS01860 ^@ http://purl.uniprot.org/uniprot/W8RNX5 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1294273:ROSELON_RS07085 ^@ http://purl.uniprot.org/uniprot/W8S502 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS11055 ^@ http://purl.uniprot.org/uniprot/W8RTZ3 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1294273:ROSELON_RS14520 ^@ http://purl.uniprot.org/uniprot/W8SS87 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS10180 ^@ http://purl.uniprot.org/uniprot/W8RTH1 ^@ Function ^@ Catalyzes the methylation of C-1 in precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A. http://togogenome.org/gene/1294273:ROSELON_RS10425 ^@ http://purl.uniprot.org/uniprot/W8RTL9 ^@ Function|||Similarity ^@ Belongs to the ribose 1,5-bisphosphokinase family.|||Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). http://togogenome.org/gene/1294273:ROSELON_RS01495 ^@ http://purl.uniprot.org/uniprot/W8SJT5 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS00440 ^@ http://purl.uniprot.org/uniprot/W8RXL6 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS04155 ^@ http://purl.uniprot.org/uniprot/W8RZI6 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1294273:ROSELON_RS06820 ^@ http://purl.uniprot.org/uniprot/W8RRN0 ^@ Caution|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1294273:ROSELON_RS14300 ^@ http://purl.uniprot.org/uniprot/W8S8P4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IlvD/Edd family.|||Binds 1 [4Fe-4S] cluster.|||Catalyzes the dehydration of 6-phospho-D-gluconate to 2-dehydro-3-deoxy-6-phospho-D-gluconate. http://togogenome.org/gene/1294273:ROSELON_RS01235 ^@ http://purl.uniprot.org/uniprot/W8S1V8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS01785 ^@ http://purl.uniprot.org/uniprot/W8RP84 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS00910 ^@ http://purl.uniprot.org/uniprot/W8RND3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS12285 ^@ http://purl.uniprot.org/uniprot/W8RUS9 ^@ Function|||Similarity ^@ Belongs to the polysaccharide deacetylase family.|||Is involved in generating a small heat-stable compound (Nod), an acylated oligomer of N-acetylglucosamine, that stimulates mitosis in various plant protoplasts. http://togogenome.org/gene/1294273:ROSELON_RS12090 ^@ http://purl.uniprot.org/uniprot/W8S7M7 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS04480 ^@ http://purl.uniprot.org/uniprot/W8S3M1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1294273:ROSELON_RS03955 ^@ http://purl.uniprot.org/uniprot/W8SL35 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1294273:ROSELON_RS10605 ^@ http://purl.uniprot.org/uniprot/W8RTS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1294273:ROSELON_RS04950 ^@ http://purl.uniprot.org/uniprot/W8S3W3 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/1294273:ROSELON_RS13285 ^@ http://purl.uniprot.org/uniprot/W8RVB3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS16220 ^@ http://purl.uniprot.org/uniprot/W8RWL8 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1294273:ROSELON_RS07040 ^@ http://purl.uniprot.org/uniprot/W8S144 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1294273:ROSELON_RS16580 ^@ http://purl.uniprot.org/uniprot/W8STE0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04100 ^@ http://purl.uniprot.org/uniprot/W8RQD9 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS09705 ^@ http://purl.uniprot.org/uniprot/W8RTD6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1294273:ROSELON_RS09370 ^@ http://purl.uniprot.org/uniprot/W8S2C5 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS12475 ^@ http://purl.uniprot.org/uniprot/W8RUS0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS10620 ^@ http://purl.uniprot.org/uniprot/W8S6S5 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1294273:ROSELON_RS10775 ^@ http://purl.uniprot.org/uniprot/W8S6U7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS04680 ^@ http://purl.uniprot.org/uniprot/W8RZW0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/1294273:ROSELON_RS08650 ^@ http://purl.uniprot.org/uniprot/W8S5U2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoH subfamily.|||Cytoplasm|||Interacts with the RNA polymerase core enzyme.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. http://togogenome.org/gene/1294273:ROSELON_RS14325 ^@ http://purl.uniprot.org/uniprot/W8S8Q2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS14515 ^@ http://purl.uniprot.org/uniprot/W8RW17 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/1294273:ROSELON_RS11915 ^@ http://purl.uniprot.org/uniprot/W8S7G4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1294273:ROSELON_RS10545 ^@ http://purl.uniprot.org/uniprot/W8RTR7 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1294273:ROSELON_RS09600 ^@ http://purl.uniprot.org/uniprot/W8S2G5 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1294273:ROSELON_RS02340 ^@ http://purl.uniprot.org/uniprot/W8SKC2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS02955 ^@ http://purl.uniprot.org/uniprot/W8RPV1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS00850 ^@ http://purl.uniprot.org/uniprot/W8RNR2 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1294273:ROSELON_RS07020 ^@ http://purl.uniprot.org/uniprot/W8RRY6 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1294273:ROSELON_RS06520 ^@ http://purl.uniprot.org/uniprot/W8RRG8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS04320 ^@ http://purl.uniprot.org/uniprot/W8RQH4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family.|||Cytoplasm|||Homotrimer. http://togogenome.org/gene/1294273:ROSELON_RS05370 ^@ http://purl.uniprot.org/uniprot/W8S087 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS04770 ^@ http://purl.uniprot.org/uniprot/W8S3U1 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1294273:ROSELON_RS02720 ^@ http://purl.uniprot.org/uniprot/W8RYU2 ^@ Function|||Subunit ^@ DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease. http://togogenome.org/gene/1294273:ROSELON_RS07325 ^@ http://purl.uniprot.org/uniprot/W8RS19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS12350 ^@ http://purl.uniprot.org/uniprot/W8RUQ0 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1294273:ROSELON_RS10350 ^@ http://purl.uniprot.org/uniprot/W8RTN7 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1294273:ROSELON_RS13215 ^@ http://purl.uniprot.org/uniprot/W8RVA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14565 ^@ http://purl.uniprot.org/uniprot/W8SSC2 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1294273:ROSELON_RS13785 ^@ http://purl.uniprot.org/uniprot/W8RVK4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MetA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1294273:ROSELON_RS01730 ^@ http://purl.uniprot.org/uniprot/W8RYA0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00535 ^@ http://purl.uniprot.org/uniprot/W8S1H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS16585 ^@ http://purl.uniprot.org/uniprot/W8S9V1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS01415 ^@ http://purl.uniprot.org/uniprot/W8RY33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS12850 ^@ http://purl.uniprot.org/uniprot/W8S4D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS01365 ^@ http://purl.uniprot.org/uniprot/W8RP14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Belongs to the major facilitator superfamily. TCR/Tet family.|||Cell inner membrane|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1294273:ROSELON_RS06245 ^@ http://purl.uniprot.org/uniprot/W8RRK3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS01965 ^@ http://purl.uniprot.org/uniprot/W8SK37 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS11660 ^@ http://purl.uniprot.org/uniprot/W8SQK5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Could be part of an ABC transporter complex.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS02665 ^@ http://purl.uniprot.org/uniprot/W8SKH4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS09955 ^@ http://purl.uniprot.org/uniprot/W8SPN4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS07550 ^@ http://purl.uniprot.org/uniprot/W8S1F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1294273:ROSELON_RS14645 ^@ http://purl.uniprot.org/uniprot/W8SSE7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1294273:ROSELON_RS01930 ^@ http://purl.uniprot.org/uniprot/W8RPB9 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1294273:ROSELON_RS09025 ^@ http://purl.uniprot.org/uniprot/W8SP21 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS16550 ^@ http://purl.uniprot.org/uniprot/W8STD5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1294273:ROSELON_RS02135 ^@ http://purl.uniprot.org/uniprot/W8RP58 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1294273:ROSELON_RS03490 ^@ http://purl.uniprot.org/uniprot/W8S328 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1294273:ROSELON_RS09650 ^@ http://purl.uniprot.org/uniprot/W8S6E8 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1294273:ROSELON_RS05650 ^@ http://purl.uniprot.org/uniprot/W8S482 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1294273:ROSELON_RS11740 ^@ http://purl.uniprot.org/uniprot/W8S7C7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1294273:ROSELON_RS03030 ^@ http://purl.uniprot.org/uniprot/W8RYY9 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1294273:ROSELON_RS06590 ^@ http://purl.uniprot.org/uniprot/W8S4P5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS16900 ^@ http://purl.uniprot.org/uniprot/W8STK8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS05700 ^@ http://purl.uniprot.org/uniprot/W8S491 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1294273:ROSELON_RS08385 ^@ http://purl.uniprot.org/uniprot/W8RSI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1294273:ROSELON_RS15960 ^@ http://purl.uniprot.org/uniprot/W8RWH2 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1294273:ROSELON_RS12570 ^@ http://purl.uniprot.org/uniprot/W8S7U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1294273:ROSELON_RS07755 ^@ http://purl.uniprot.org/uniprot/W8S1J0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS11850 ^@ http://purl.uniprot.org/uniprot/W8RUE8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS06660 ^@ http://purl.uniprot.org/uniprot/W8S0W3 ^@ Function|||Similarity ^@ Belongs to the peroxiredoxin family. Prx5 subfamily.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1294273:ROSELON_RS09835 ^@ http://purl.uniprot.org/uniprot/W8RTF4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1294273:ROSELON_RS14530 ^@ http://purl.uniprot.org/uniprot/W8S592 ^@ Similarity ^@ Belongs to the HIBADH-related family. http://togogenome.org/gene/1294273:ROSELON_RS13620 ^@ http://purl.uniprot.org/uniprot/W8S8C1 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1294273:ROSELON_RS11390 ^@ http://purl.uniprot.org/uniprot/W8RU59 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1294273:ROSELON_RS10240 ^@ http://purl.uniprot.org/uniprot/W8S2W6 ^@ Function ^@ Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/1294273:ROSELON_RS12260 ^@ http://purl.uniprot.org/uniprot/W8RUS3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS12155 ^@ http://purl.uniprot.org/uniprot/W8RUM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS04285 ^@ http://purl.uniprot.org/uniprot/W8S3H3 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1294273:ROSELON_RS01000 ^@ http://purl.uniprot.org/uniprot/W8RXW5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by fructose 1,6-bisphosphate (FBP).|||Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS11340 ^@ http://purl.uniprot.org/uniprot/W8RU49 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1294273:ROSELON_RS01765 ^@ http://purl.uniprot.org/uniprot/W8RNV2 ^@ Similarity ^@ Belongs to the NTE family. http://togogenome.org/gene/1294273:ROSELON_RS03540 ^@ http://purl.uniprot.org/uniprot/W8RQ41 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1294273:ROSELON_RS07465 ^@ http://purl.uniprot.org/uniprot/W8RS38 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/1294273:ROSELON_RS08200 ^@ http://purl.uniprot.org/uniprot/W8S1R5 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS14350 ^@ http://purl.uniprot.org/uniprot/W8SS46 ^@ Similarity ^@ Belongs to the bacterial glucokinase family. http://togogenome.org/gene/1294273:ROSELON_RS01585 ^@ http://purl.uniprot.org/uniprot/W8RP42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PucC family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13455 ^@ http://purl.uniprot.org/uniprot/W8S899 ^@ Caution|||Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Belongs to the IspF family.|||Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS06790 ^@ http://purl.uniprot.org/uniprot/W8S0Z2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS03070 ^@ http://purl.uniprot.org/uniprot/W8SKN8 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1294273:ROSELON_RS09300 ^@ http://purl.uniprot.org/uniprot/W8SP80 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS12985 ^@ http://purl.uniprot.org/uniprot/W8SRD2 ^@ Function|||Subcellular Location Annotation ^@ Could be a virulence factor.|||Secreted http://togogenome.org/gene/1294273:ROSELON_RS04695 ^@ http://purl.uniprot.org/uniprot/W8SLK9 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/1294273:ROSELON_RS04350 ^@ http://purl.uniprot.org/uniprot/W8RQ82 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M20A family. DapE subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS03525 ^@ http://purl.uniprot.org/uniprot/W8SKW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS09130 ^@ http://purl.uniprot.org/uniprot/W8RT32 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1294273:ROSELON_RS00280 ^@ http://purl.uniprot.org/uniprot/W8S1D1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS07590 ^@ http://purl.uniprot.org/uniprot/W8RS57 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1294273:ROSELON_RS00335 ^@ http://purl.uniprot.org/uniprot/W8RXJ8 ^@ Cofactor|||Similarity ^@ Belongs to the nitroreductase family.|||Binds 1 FMN per subunit. http://togogenome.org/gene/1294273:ROSELON_RS10665 ^@ http://purl.uniprot.org/uniprot/W8S6T1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS15785 ^@ http://purl.uniprot.org/uniprot/W8S9G9 ^@ Similarity ^@ Belongs to the dihydropyrimidine dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS01775 ^@ http://purl.uniprot.org/uniprot/W8S263 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1294273:ROSELON_RS14875 ^@ http://purl.uniprot.org/uniprot/W8RWB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1294273:ROSELON_RS08070 ^@ http://purl.uniprot.org/uniprot/W8SNH7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cytochrome b560 family.|||Membrane|||Membrane-anchoring subunit of succinate dehydrogenase (SDH).|||Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.|||The heme is bound between the two transmembrane subunits. http://togogenome.org/gene/1294273:ROSELON_RS01880 ^@ http://purl.uniprot.org/uniprot/W8RPA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00815 ^@ http://purl.uniprot.org/uniprot/W8RNB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1294273:ROSELON_RS00395 ^@ http://purl.uniprot.org/uniprot/W8SJ79 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1294273:ROSELON_RS13795 ^@ http://purl.uniprot.org/uniprot/W8S8E9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1294273:ROSELON_RS04860 ^@ http://purl.uniprot.org/uniprot/W8S003 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS11115 ^@ http://purl.uniprot.org/uniprot/W8SQ77 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS05090 ^@ http://purl.uniprot.org/uniprot/W8RQQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.|||Belongs to the antenna complex beta subunit family.|||Cell inner membrane|||Membrane|||The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components. http://togogenome.org/gene/1294273:ROSELON_RS07805 ^@ http://purl.uniprot.org/uniprot/W8S1J7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1294273:ROSELON_RS13655 ^@ http://purl.uniprot.org/uniprot/W8S4R6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS10280 ^@ http://purl.uniprot.org/uniprot/W8RTJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS13690 ^@ http://purl.uniprot.org/uniprot/W8RVI3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1294273:ROSELON_RS06645 ^@ http://purl.uniprot.org/uniprot/W8RRJ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00080 ^@ http://purl.uniprot.org/uniprot/W8RNB5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1294273:ROSELON_RS14915 ^@ http://purl.uniprot.org/uniprot/W8S5I3 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS12880 ^@ http://purl.uniprot.org/uniprot/W8RUY3 ^@ Similarity ^@ Belongs to the DNA photolyase family. http://togogenome.org/gene/1294273:ROSELON_RS05610 ^@ http://purl.uniprot.org/uniprot/W8RR79 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1294273:ROSELON_RS04925 ^@ http://purl.uniprot.org/uniprot/W8S3V9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1294273:ROSELON_RS00360 ^@ http://purl.uniprot.org/uniprot/W8RXK2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS02375 ^@ http://purl.uniprot.org/uniprot/W8RYN6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS09160 ^@ http://purl.uniprot.org/uniprot/W8RSX2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1294273:ROSELON_RS09175 ^@ http://purl.uniprot.org/uniprot/W8S287 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1294273:ROSELON_RS10590 ^@ http://purl.uniprot.org/uniprot/W8SPY5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS01505 ^@ http://purl.uniprot.org/uniprot/W8RY52 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS10800 ^@ http://purl.uniprot.org/uniprot/W8S363 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS11230 ^@ http://purl.uniprot.org/uniprot/W8S717 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS08435 ^@ http://purl.uniprot.org/uniprot/W8SNQ0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1294273:ROSELON_RS01535 ^@ http://purl.uniprot.org/uniprot/W8S208 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/1294273:ROSELON_RS02005 ^@ http://purl.uniprot.org/uniprot/W8RPD6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1294273:ROSELON_RS00085 ^@ http://purl.uniprot.org/uniprot/W8RN10 ^@ Similarity ^@ Belongs to the complex I 75 kDa subunit family. http://togogenome.org/gene/1294273:ROSELON_RS13265 ^@ http://purl.uniprot.org/uniprot/W8SRI0 ^@ Caution|||Function|||Similarity ^@ Belongs to the Dus family. DusA subfamily.|||Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS10660 ^@ http://purl.uniprot.org/uniprot/W8SPZ6 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1294273:ROSELON_RS00060 ^@ http://purl.uniprot.org/uniprot/W8RN09 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS10640 ^@ http://purl.uniprot.org/uniprot/W8S6S8 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1294273:ROSELON_RS13350 ^@ http://purl.uniprot.org/uniprot/W8S4M0 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1294273:ROSELON_RS16865 ^@ http://purl.uniprot.org/uniprot/W8RWY1 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1294273:ROSELON_RS07050 ^@ http://purl.uniprot.org/uniprot/W8RRT3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS06760 ^@ http://purl.uniprot.org/uniprot/W8S4S7 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1294273:ROSELON_RS04065 ^@ http://purl.uniprot.org/uniprot/W8S3D1 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1294273:ROSELON_RS01175 ^@ http://purl.uniprot.org/uniprot/W8RNX4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1294273:ROSELON_RS02445 ^@ http://purl.uniprot.org/uniprot/W8RYP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS00905 ^@ http://purl.uniprot.org/uniprot/W8RNS0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS08490 ^@ http://purl.uniprot.org/uniprot/W8S5R4 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1294273:ROSELON_RS12275 ^@ http://purl.uniprot.org/uniprot/W8S447 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1294273:ROSELON_RS14770 ^@ http://purl.uniprot.org/uniprot/W8S5F4 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1294273:ROSELON_RS12970 ^@ http://purl.uniprot.org/uniprot/W8S810 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. L-carnitine dehydrogenase subfamily.|||Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3-dehydrocarnitine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS03825 ^@ http://purl.uniprot.org/uniprot/W8SL13 ^@ Similarity ^@ Belongs to the SDHAF4 family. http://togogenome.org/gene/1294273:ROSELON_RS12735 ^@ http://purl.uniprot.org/uniprot/W8RUW2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/1294273:ROSELON_RS06175 ^@ http://purl.uniprot.org/uniprot/W8SMD5 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1294273:ROSELON_RS16100 ^@ http://purl.uniprot.org/uniprot/W8ST64 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS07255 ^@ http://purl.uniprot.org/uniprot/W8RS08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1294273:ROSELON_RS07350 ^@ http://purl.uniprot.org/uniprot/W8RS22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1294273:ROSELON_RS03190 ^@ http://purl.uniprot.org/uniprot/W8SKQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1294273:ROSELON_RS00445 ^@ http://purl.uniprot.org/uniprot/W8RNI1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1294273:ROSELON_RS15275 ^@ http://purl.uniprot.org/uniprot/W8SSP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1294273:ROSELON_RS02950 ^@ http://purl.uniprot.org/uniprot/W8RYX5 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1294273:ROSELON_RS09180 ^@ http://purl.uniprot.org/uniprot/W8RT41 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/1294273:ROSELON_RS09315 ^@ http://purl.uniprot.org/uniprot/W8RT00 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS09855 ^@ http://purl.uniprot.org/uniprot/W8S2P4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS01980 ^@ http://purl.uniprot.org/uniprot/W8RPC9 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS14040 ^@ http://purl.uniprot.org/uniprot/W8S8J1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 68 family. http://togogenome.org/gene/1294273:ROSELON_RS16065 ^@ http://purl.uniprot.org/uniprot/W8RWJ1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1294273:ROSELON_RS15020 ^@ http://purl.uniprot.org/uniprot/W8SSK7 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.|||In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1294273:ROSELON_RS08145 ^@ http://purl.uniprot.org/uniprot/W8S1Q8 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1294273:ROSELON_RS09035 ^@ http://purl.uniprot.org/uniprot/W8S258 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LysR transcriptional regulatory family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS01470 ^@ http://purl.uniprot.org/uniprot/W8RNP0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1294273:ROSELON_RS04735 ^@ http://purl.uniprot.org/uniprot/W8RQT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS14270 ^@ http://purl.uniprot.org/uniprot/W8SS29 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS13440 ^@ http://purl.uniprot.org/uniprot/W8RV80 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1294273:ROSELON_RS02055 ^@ http://purl.uniprot.org/uniprot/W8RP13 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1294273:ROSELON_RS10880 ^@ http://purl.uniprot.org/uniprot/W8RTX7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS17035 ^@ http://purl.uniprot.org/uniprot/W8RX18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS00325 ^@ http://purl.uniprot.org/uniprot/W8SJ67 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1294273:ROSELON_RS04035 ^@ http://purl.uniprot.org/uniprot/W8SL50 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS13550 ^@ http://purl.uniprot.org/uniprot/W8S4Q0 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1294273:ROSELON_RS17135 ^@ http://purl.uniprot.org/uniprot/W8S6L9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS16545 ^@ http://purl.uniprot.org/uniprot/W8RX50 ^@ Similarity ^@ Belongs to the UPF0262 family. http://togogenome.org/gene/1294273:ROSELON_RS03845 ^@ http://purl.uniprot.org/uniprot/W8RPY0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1294273:ROSELON_RS15980 ^@ http://purl.uniprot.org/uniprot/W8S618 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1294273:ROSELON_RS14815 ^@ http://purl.uniprot.org/uniprot/W8S5G3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS17130 ^@ http://purl.uniprot.org/uniprot/W8SA94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14265 ^@ http://purl.uniprot.org/uniprot/W8RVU9 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1294273:ROSELON_RS14660 ^@ http://purl.uniprot.org/uniprot/W8RW74 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS03980 ^@ http://purl.uniprot.org/uniprot/W8RQ08 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1294273:ROSELON_RS12225 ^@ http://purl.uniprot.org/uniprot/W8S439 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1294273:ROSELON_RS10935 ^@ http://purl.uniprot.org/uniprot/W8SQ45 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1294273:ROSELON_RS11565 ^@ http://purl.uniprot.org/uniprot/W8SQI3 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1294273:ROSELON_RS01955 ^@ http://purl.uniprot.org/uniprot/W8RPC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13560 ^@ http://purl.uniprot.org/uniprot/W8SRN3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmE/CycJ family.|||Cell membrane|||Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. http://togogenome.org/gene/1294273:ROSELON_RS07505 ^@ http://purl.uniprot.org/uniprot/W8S1F3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS02265 ^@ http://purl.uniprot.org/uniprot/W8RPK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS12235 ^@ http://purl.uniprot.org/uniprot/W8RUR9 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1294273:ROSELON_RS16015 ^@ http://purl.uniprot.org/uniprot/W8RWV7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS07945 ^@ http://purl.uniprot.org/uniprot/W8S1L9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS16245 ^@ http://purl.uniprot.org/uniprot/W8S667 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS06965 ^@ http://purl.uniprot.org/uniprot/W8S4X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS16040 ^@ http://purl.uniprot.org/uniprot/W8RWW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1294273:ROSELON_RS14925 ^@ http://purl.uniprot.org/uniprot/W8RWC1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS08930 ^@ http://purl.uniprot.org/uniprot/W8S5Y9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1294273:ROSELON_RS00795 ^@ http://purl.uniprot.org/uniprot/W8SJE8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1294273:ROSELON_RS06770 ^@ http://purl.uniprot.org/uniprot/W8RRT7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS11630 ^@ http://purl.uniprot.org/uniprot/W8RUC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS03145 ^@ http://purl.uniprot.org/uniprot/W8S2Y0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1294273:ROSELON_RS02935 ^@ http://purl.uniprot.org/uniprot/W8SKL6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1294273:ROSELON_RS07540 ^@ http://purl.uniprot.org/uniprot/W8SN99 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1294273:ROSELON_RS03330 ^@ http://purl.uniprot.org/uniprot/W8RPM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS10705 ^@ http://purl.uniprot.org/uniprot/W8S6T7 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1294273:ROSELON_RS01605 ^@ http://purl.uniprot.org/uniprot/W8RY66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS10260 ^@ http://purl.uniprot.org/uniprot/W8RTI6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1294273:ROSELON_RS04730 ^@ http://purl.uniprot.org/uniprot/W8RZY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS11925 ^@ http://purl.uniprot.org/uniprot/W8RUG3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1294273:ROSELON_RS07815 ^@ http://purl.uniprot.org/uniprot/W8RS97 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1294273:ROSELON_RS15755 ^@ http://purl.uniprot.org/uniprot/W8SSZ2 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1294273:ROSELON_RS01065 ^@ http://purl.uniprot.org/uniprot/W8SJK1 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS07440 ^@ http://purl.uniprot.org/uniprot/W8RS96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1294273:ROSELON_RS03440 ^@ http://purl.uniprot.org/uniprot/W8RZ58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS03380 ^@ http://purl.uniprot.org/uniprot/W8RPN8 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1294273:ROSELON_RS16860 ^@ http://purl.uniprot.org/uniprot/W8S6F7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS11635 ^@ http://purl.uniprot.org/uniprot/W8SQJ9 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1294273:ROSELON_RS06885 ^@ http://purl.uniprot.org/uniprot/W8S112 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1294273:ROSELON_RS05095 ^@ http://purl.uniprot.org/uniprot/W8SLT2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers.|||Belongs to the antenna complex alpha subunit family.|||Cell inner membrane|||Membrane|||The core complex is formed by different alpha and beta chains, binding bacteriochlorophyll molecules, and arranged most probably in tetrameric structures disposed around the reaction center. The non-pigmented gamma chains may constitute additional components. http://togogenome.org/gene/1294273:ROSELON_RS07725 ^@ http://purl.uniprot.org/uniprot/W8S5D0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1294273:ROSELON_RS04775 ^@ http://purl.uniprot.org/uniprot/W8RZZ5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1294273:ROSELON_RS16795 ^@ http://purl.uniprot.org/uniprot/W8S6E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 7 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS09725 ^@ http://purl.uniprot.org/uniprot/W8S2M0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS05340 ^@ http://purl.uniprot.org/uniprot/W8S081 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS09560 ^@ http://purl.uniprot.org/uniprot/W8RTA3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS10100 ^@ http://purl.uniprot.org/uniprot/W8SPQ8 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS01370 ^@ http://purl.uniprot.org/uniprot/W8RNL8 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1294273:ROSELON_RS05155 ^@ http://purl.uniprot.org/uniprot/W8RR05 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the BchN/ChlN family.|||Binds 1 [4Fe-4S] cluster per heterodimer. The cluster is bound at the heterodimer interface by residues from both subunits.|||Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex.|||Protochlorophyllide reductase is composed of three subunits; BchL, BchN and BchB. Forms a heterotetramer of two BchB and two BchN subunits. http://togogenome.org/gene/1294273:ROSELON_RS04930 ^@ http://purl.uniprot.org/uniprot/W8S012 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1294273:ROSELON_RS15670 ^@ http://purl.uniprot.org/uniprot/W8S5W9 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1294273:ROSELON_RS04175 ^@ http://purl.uniprot.org/uniprot/W8SL76 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS10575 ^@ http://purl.uniprot.org/uniprot/W8RTR9 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS02980 ^@ http://purl.uniprot.org/uniprot/W8RPV5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS04375 ^@ http://purl.uniprot.org/uniprot/W8RQI3 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07150 ^@ http://purl.uniprot.org/uniprot/W8RS45 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1294273:ROSELON_RS14885 ^@ http://purl.uniprot.org/uniprot/W8S932 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS15890 ^@ http://purl.uniprot.org/uniprot/W8RWG0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1294273:ROSELON_RS13775 ^@ http://purl.uniprot.org/uniprot/W8S4U2 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/1294273:ROSELON_RS06640 ^@ http://purl.uniprot.org/uniprot/W8RRR7 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1294273:ROSELON_RS06035 ^@ http://purl.uniprot.org/uniprot/W8RR62 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS01555 ^@ http://purl.uniprot.org/uniprot/W8RP38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Could be part of an ABC transporter complex.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS14315 ^@ http://purl.uniprot.org/uniprot/W8RVW4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS07800 ^@ http://purl.uniprot.org/uniprot/W8S5E1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1294273:ROSELON_RS16620 ^@ http://purl.uniprot.org/uniprot/W8RX65 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1294273:ROSELON_RS17370 ^@ http://purl.uniprot.org/uniprot/W8S434 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RTX toxin acyltransferase family.|||Cytoplasm|||Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin. http://togogenome.org/gene/1294273:ROSELON_RS15940 ^@ http://purl.uniprot.org/uniprot/W8RWU2 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1294273:ROSELON_RS13200 ^@ http://purl.uniprot.org/uniprot/W8S853 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS16035 ^@ http://purl.uniprot.org/uniprot/W8RWI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS13870 ^@ http://purl.uniprot.org/uniprot/W8S8G1 ^@ Similarity ^@ Belongs to the HpcH/HpaI aldolase family. http://togogenome.org/gene/1294273:ROSELON_RS16045 ^@ http://purl.uniprot.org/uniprot/W8ST54 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS16140 ^@ http://purl.uniprot.org/uniprot/W8S653 ^@ Similarity|||Subunit ^@ Belongs to the P(II) protein family.|||Homotrimer. http://togogenome.org/gene/1294273:ROSELON_RS16360 ^@ http://purl.uniprot.org/uniprot/W8RWN7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07340 ^@ http://purl.uniprot.org/uniprot/W8S1C9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1294273:ROSELON_RS17650 ^@ http://purl.uniprot.org/uniprot/W8RXL3 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1294273:ROSELON_RS07275 ^@ http://purl.uniprot.org/uniprot/W8RS66 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1294273:ROSELON_RS16235 ^@ http://purl.uniprot.org/uniprot/W8ST88 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS03220 ^@ http://purl.uniprot.org/uniprot/W8RPZ3 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1294273:ROSELON_RS08970 ^@ http://purl.uniprot.org/uniprot/W8SP11 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1294273:ROSELON_RS09565 ^@ http://purl.uniprot.org/uniprot/W8RT49 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS04815 ^@ http://purl.uniprot.org/uniprot/W8SLP2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS14155 ^@ http://purl.uniprot.org/uniprot/W8RVK3 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS03740 ^@ http://purl.uniprot.org/uniprot/W8RQ71 ^@ Similarity ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Belongs to the peroxiredoxin family. Prx6 subfamily. http://togogenome.org/gene/1294273:ROSELON_RS02125 ^@ http://purl.uniprot.org/uniprot/W8RYK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1294273:ROSELON_RS06935 ^@ http://purl.uniprot.org/uniprot/W8SMV7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS16455 ^@ http://purl.uniprot.org/uniprot/W8STC1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS14950 ^@ http://purl.uniprot.org/uniprot/W8RWC4 ^@ Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1294273:ROSELON_RS08925 ^@ http://purl.uniprot.org/uniprot/W8SP00 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/1294273:ROSELON_RS12455 ^@ http://purl.uniprot.org/uniprot/W8SR40 ^@ Similarity ^@ Belongs to the GcvT family. http://togogenome.org/gene/1294273:ROSELON_RS11205 ^@ http://purl.uniprot.org/uniprot/W8RU18 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1294273:ROSELON_RS15100 ^@ http://purl.uniprot.org/uniprot/W8RW36 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS13810 ^@ http://purl.uniprot.org/uniprot/W8SRT6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS00665 ^@ http://purl.uniprot.org/uniprot/W8RN90 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS09200 ^@ http://purl.uniprot.org/uniprot/W8S636 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1294273:ROSELON_RS12575 ^@ http://purl.uniprot.org/uniprot/W8S489 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1294273:ROSELON_RS14790 ^@ http://purl.uniprot.org/uniprot/W8S915 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell inner membrane|||Cell membrane http://togogenome.org/gene/1294273:ROSELON_RS08735 ^@ http://purl.uniprot.org/uniprot/W8RSP4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1294273:ROSELON_RS05320 ^@ http://purl.uniprot.org/uniprot/W8RR26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS06020 ^@ http://purl.uniprot.org/uniprot/W8S0J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS06920 ^@ http://purl.uniprot.org/uniprot/W8SMV0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1294273:ROSELON_RS07840 ^@ http://purl.uniprot.org/uniprot/W8RSA1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cell inner membrane|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1294273:ROSELON_RS03095 ^@ http://purl.uniprot.org/uniprot/W8SKP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1294273:ROSELON_RS15485 ^@ http://purl.uniprot.org/uniprot/W8S5T4 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1294273:ROSELON_RS15095 ^@ http://purl.uniprot.org/uniprot/W8S5L6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1294273:ROSELON_RS05685 ^@ http://purl.uniprot.org/uniprot/W8RR95 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1294273:ROSELON_RS14550 ^@ http://purl.uniprot.org/uniprot/W8S8V2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/1294273:ROSELON_RS00090 ^@ http://purl.uniprot.org/uniprot/W8SJ25 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1294273:ROSELON_RS06980 ^@ http://purl.uniprot.org/uniprot/W8SMX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS11665 ^@ http://purl.uniprot.org/uniprot/W8S7B1 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1294273:ROSELON_RS08265 ^@ http://purl.uniprot.org/uniprot/W8S5M0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1294273:ROSELON_RS07120 ^@ http://purl.uniprot.org/uniprot/W8S164 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1294273:ROSELON_RS02675 ^@ http://purl.uniprot.org/uniprot/W8RYT3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS08195 ^@ http://purl.uniprot.org/uniprot/W8S5K7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS17390 ^@ http://purl.uniprot.org/uniprot/W8S0B8 ^@ Function ^@ Converts beta-D-mannuronic acid (M) to alpha-L-guluronic acid (G), producing a polymer with gel-forming capacity, required for the formation of the cyst coat. http://togogenome.org/gene/1294273:ROSELON_RS06095 ^@ http://purl.uniprot.org/uniprot/W8RR77 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1294273:ROSELON_RS01625 ^@ http://purl.uniprot.org/uniprot/W8S225 ^@ Function|||Similarity ^@ Belongs to the gamma-glutamylcyclotransferase family.|||Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. http://togogenome.org/gene/1294273:ROSELON_RS04090 ^@ http://purl.uniprot.org/uniprot/W8S3D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS05635 ^@ http://purl.uniprot.org/uniprot/W8RR85 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1294273:ROSELON_RS12460 ^@ http://purl.uniprot.org/uniprot/W8S7T3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0053 family. Hemolysin C subfamily.|||Membrane http://togogenome.org/gene/1294273:ROSELON_RS07045 ^@ http://purl.uniprot.org/uniprot/W8RRZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1294273:ROSELON_RS16145 ^@ http://purl.uniprot.org/uniprot/W8RWK4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutamine synthetase family.|||Catalyzes the ATP-dependent biosynthesis of glutamine from glutamate and ammonia.|||Oligomer of 12 subunits arranged in the form of two hexameric ring. http://togogenome.org/gene/1294273:ROSELON_RS06450 ^@ http://purl.uniprot.org/uniprot/W8RRF1 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1294273:ROSELON_RS01425 ^@ http://purl.uniprot.org/uniprot/W8RNM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1294273:ROSELON_RS03325 ^@ http://purl.uniprot.org/uniprot/W8RQ10 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS07405 ^@ http://purl.uniprot.org/uniprot/W8SN76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1294273:ROSELON_RS01130 ^@ http://purl.uniprot.org/uniprot/W8RNW5 ^@ Similarity ^@ Belongs to the UPF0276 family. http://togogenome.org/gene/1294273:ROSELON_RS02155 ^@ http://purl.uniprot.org/uniprot/W8RPJ1 ^@ Function ^@ Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. http://togogenome.org/gene/1294273:ROSELON_RS09775 ^@ http://purl.uniprot.org/uniprot/W8RTE6 ^@ Similarity ^@ Belongs to the UbiH/COQ6 family. http://togogenome.org/gene/1294273:ROSELON_RS00270 ^@ http://purl.uniprot.org/uniprot/W8RN36 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1294273:ROSELON_RS16460 ^@ http://purl.uniprot.org/uniprot/W8S9T5 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1294273:ROSELON_RS08340 ^@ http://purl.uniprot.org/uniprot/W8S5N4 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1294273:ROSELON_RS09430 ^@ http://purl.uniprot.org/uniprot/W8RT83 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1294273:ROSELON_RS06200 ^@ http://purl.uniprot.org/uniprot/W8SMD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FlgA family.|||Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly.|||Periplasm http://togogenome.org/gene/1294273:ROSELON_RS05860 ^@ http://purl.uniprot.org/uniprot/W8SM69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1294273:ROSELON_RS07450 ^@ http://purl.uniprot.org/uniprot/W8SN83 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1294273:ROSELON_RS06180 ^@ http://purl.uniprot.org/uniprot/W8S4H9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1294273:ROSELON_RS03345 ^@ http://purl.uniprot.org/uniprot/W8RZ40 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1294273:ROSELON_RS00275 ^@ http://purl.uniprot.org/uniprot/W8SJ57 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1294273:ROSELON_RS07480 ^@ http://purl.uniprot.org/uniprot/W8S1E9 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1294273:ROSELON_RS12585 ^@ http://purl.uniprot.org/uniprot/W8RUX3 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1294273:ROSELON_RS04150 ^@ http://purl.uniprot.org/uniprot/W8S3E9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1294273:ROSELON_RS13330 ^@ http://purl.uniprot.org/uniprot/W8RV63 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1294273:ROSELON_RS10600 ^@ http://purl.uniprot.org/uniprot/W8S318 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.