http://togogenome.org/gene/1246995:AFR_RS36835 ^@ http://purl.uniprot.org/uniprot/U5W8T4 ^@ Function|||Similarity ^@ Belongs to the CofC family.|||Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. http://togogenome.org/gene/1246995:AFR_RS40535 ^@ http://purl.uniprot.org/uniprot/U5WBF7 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS42075 ^@ http://purl.uniprot.org/uniprot/U5WFD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18025 ^@ http://purl.uniprot.org/uniprot/U5VXY1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/1246995:AFR_RS09495 ^@ http://purl.uniprot.org/uniprot/U5VWS8 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1246995:AFR_RS11230 ^@ http://purl.uniprot.org/uniprot/U5VUG4 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1246995:AFR_RS01710 ^@ http://purl.uniprot.org/uniprot/U5VSL7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS11725 ^@ http://purl.uniprot.org/uniprot/U5VUU2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS10060 ^@ http://purl.uniprot.org/uniprot/U5VX32 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CobB/CobQ family. GatD subfamily.|||Forms a heterodimer with MurT.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The GatD subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia. The resulting ammonia molecule is channeled to the active site of MurT. http://togogenome.org/gene/1246995:AFR_RS08310 ^@ http://purl.uniprot.org/uniprot/U5VW91 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS01520 ^@ http://purl.uniprot.org/uniprot/U5VNS5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnE family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. http://togogenome.org/gene/1246995:AFR_RS30655 ^@ http://purl.uniprot.org/uniprot/U5W8U1 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1246995:AFR_RS30375 ^@ http://purl.uniprot.org/uniprot/U5W8J8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS39880 ^@ http://purl.uniprot.org/uniprot/U5WAH5 ^@ Similarity ^@ Belongs to the PAPS reductase family. CysD subfamily. http://togogenome.org/gene/1246995:AFR_RS07640 ^@ http://purl.uniprot.org/uniprot/U5VSF6 ^@ Caution|||Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS16120 ^@ http://purl.uniprot.org/uniprot/U5VX85 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1246995:AFR_RS36560 ^@ http://purl.uniprot.org/uniprot/U5W8K1 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS18965 ^@ http://purl.uniprot.org/uniprot/U5VZ53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS06265 ^@ http://purl.uniprot.org/uniprot/U5VRT0 ^@ Similarity ^@ Belongs to the ACC deaminase/D-cysteine desulfhydrase family. http://togogenome.org/gene/1246995:AFR_RS10295 ^@ http://purl.uniprot.org/uniprot/U5VU39 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS36490 ^@ http://purl.uniprot.org/uniprot/U5W8P3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1246995:AFR_RS04305 ^@ http://purl.uniprot.org/uniprot/U5VQR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS11825 ^@ http://purl.uniprot.org/uniprot/U5VUV9 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/1246995:AFR_RS10395 ^@ http://purl.uniprot.org/uniprot/U5VU59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1246995:AFR_RS08780 ^@ http://purl.uniprot.org/uniprot/U5VT84 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS16160 ^@ http://purl.uniprot.org/uniprot/U5W0M6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS06325 ^@ http://purl.uniprot.org/uniprot/U5VRS1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS02035 ^@ http://purl.uniprot.org/uniprot/U5VSJ7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS42580 ^@ http://purl.uniprot.org/uniprot/U5WFB1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1246995:AFR_RS13295 ^@ http://purl.uniprot.org/uniprot/U5VZ23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS23380 ^@ http://purl.uniprot.org/uniprot/U5W196 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1246995:AFR_RS13910 ^@ http://purl.uniprot.org/uniprot/U5VW43 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1246995:AFR_RS37935 ^@ http://purl.uniprot.org/uniprot/U5W9V4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS05490 ^@ http://purl.uniprot.org/uniprot/U5VR96 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39845 ^@ http://purl.uniprot.org/uniprot/U5WE36 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1246995:AFR_RS01120 ^@ http://purl.uniprot.org/uniprot/U5VNF7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS40825 ^@ http://purl.uniprot.org/uniprot/U5WB57 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1246995:AFR_RS14550 ^@ http://purl.uniprot.org/uniprot/U5VWE0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS09410 ^@ http://purl.uniprot.org/uniprot/U5VT57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS26420 ^@ http://purl.uniprot.org/uniprot/U5W312 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/1246995:AFR_RS23705 ^@ http://purl.uniprot.org/uniprot/U5W4Q5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS15150 ^@ http://purl.uniprot.org/uniprot/U5VZZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39175 ^@ http://purl.uniprot.org/uniprot/U5WAB1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS31235 ^@ http://purl.uniprot.org/uniprot/U5W640 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1246995:AFR_RS42630 ^@ http://purl.uniprot.org/uniprot/U5WFC0 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1246995:AFR_RS30370 ^@ http://purl.uniprot.org/uniprot/U5W580 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1246995:AFR_RS31305 ^@ http://purl.uniprot.org/uniprot/U5W972 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS00475 ^@ http://purl.uniprot.org/uniprot/U5VRU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS35165 ^@ http://purl.uniprot.org/uniprot/U5W7S0 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1246995:AFR_RS22405 ^@ http://purl.uniprot.org/uniprot/U5W412 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS01865 ^@ http://purl.uniprot.org/uniprot/U5VPC0 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS39690 ^@ http://purl.uniprot.org/uniprot/U5WDQ7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS19700 ^@ http://purl.uniprot.org/uniprot/U5VZH8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Part of an ABC transporter complex. Responsible for energy coupling to the transport system. http://togogenome.org/gene/1246995:AFR_RS32500 ^@ http://purl.uniprot.org/uniprot/U5W6F5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family.|||Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/1246995:AFR_RS38735 ^@ http://purl.uniprot.org/uniprot/U5WDD8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS22430 ^@ http://purl.uniprot.org/uniprot/U5W417 ^@ Similarity ^@ Belongs to the DszC flavin monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS11505 ^@ http://purl.uniprot.org/uniprot/U5VXZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS37310 ^@ http://purl.uniprot.org/uniprot/U5W912 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS16000 ^@ http://purl.uniprot.org/uniprot/U5W0F1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1246995:AFR_RS41585 ^@ http://purl.uniprot.org/uniprot/U5WBK2 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1246995:AFR_RS30670 ^@ http://purl.uniprot.org/uniprot/U5W5E0 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1246995:AFR_RS19740 ^@ http://purl.uniprot.org/uniprot/U5W2I1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1246995:AFR_RS20945 ^@ http://purl.uniprot.org/uniprot/U5W071 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1246995:AFR_RS35970 ^@ http://purl.uniprot.org/uniprot/U5W8E6 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1246995:AFR_RS02670 ^@ http://purl.uniprot.org/uniprot/U5VPB8 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1246995:AFR_RS00805 ^@ http://purl.uniprot.org/uniprot/U5VNS1 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/1246995:AFR_RS30800 ^@ http://purl.uniprot.org/uniprot/U5W8S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1246995:AFR_RS02885 ^@ http://purl.uniprot.org/uniprot/U5VT74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39185 ^@ http://purl.uniprot.org/uniprot/U5WDR4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09815 ^@ http://purl.uniprot.org/uniprot/U5VWY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS22780 ^@ http://purl.uniprot.org/uniprot/U5W487 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS01760 ^@ http://purl.uniprot.org/uniprot/U5VSM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS27670 ^@ http://purl.uniprot.org/uniprot/U5W423 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1246995:AFR_RS14360 ^@ http://purl.uniprot.org/uniprot/U5VZR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39890 ^@ http://purl.uniprot.org/uniprot/U5WDU6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS01825 ^@ http://purl.uniprot.org/uniprot/U5VPC3 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1246995:AFR_RS31745 ^@ http://purl.uniprot.org/uniprot/U5W9J8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1246995:AFR_RS42705 ^@ http://purl.uniprot.org/uniprot/U5WFD5 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1246995:AFR_RS27225 ^@ http://purl.uniprot.org/uniprot/U5W6X8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/1246995:AFR_RS40715 ^@ http://purl.uniprot.org/uniprot/U5WBI6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane|||Plays a role in the flagellum-specific transport system. http://togogenome.org/gene/1246995:AFR_RS40510 ^@ http://purl.uniprot.org/uniprot/U5WBF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyltransferase group 1 family. MshA subfamily.|||Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2-acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS36595 ^@ http://purl.uniprot.org/uniprot/U5WC39 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1246995:AFR_RS22900 ^@ http://purl.uniprot.org/uniprot/U5W0Z7 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1246995:AFR_RS10375 ^@ http://purl.uniprot.org/uniprot/U5VTL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS43225 ^@ http://purl.uniprot.org/uniprot/U5WCH0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1246995:AFR_RS04485 ^@ http://purl.uniprot.org/uniprot/U5VQR3 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1246995:AFR_RS36465 ^@ http://purl.uniprot.org/uniprot/U5W8P0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1246995:AFR_RS06620 ^@ http://purl.uniprot.org/uniprot/U5VVF0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS00180 ^@ http://purl.uniprot.org/uniprot/U5VNG2 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1246995:AFR_RS02975 ^@ http://purl.uniprot.org/uniprot/U5VPZ4 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS27560 ^@ http://purl.uniprot.org/uniprot/U5W6Z0 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS19255 ^@ http://purl.uniprot.org/uniprot/U5VZ11 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS37080 ^@ http://purl.uniprot.org/uniprot/U5W8X0 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1246995:AFR_RS40595 ^@ http://purl.uniprot.org/uniprot/U5WB08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1246995:AFR_RS05915 ^@ http://purl.uniprot.org/uniprot/U5VR57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1246995:AFR_RS08290 ^@ http://purl.uniprot.org/uniprot/U5VSY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS09020 ^@ http://purl.uniprot.org/uniprot/U5VTB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS31060 ^@ http://purl.uniprot.org/uniprot/U5W601 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease beta subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1246995:AFR_RS32085 ^@ http://purl.uniprot.org/uniprot/U5W699 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS14260 ^@ http://purl.uniprot.org/uniprot/U5VWG3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS01755 ^@ http://purl.uniprot.org/uniprot/U5VSE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS40695 ^@ http://purl.uniprot.org/uniprot/U5WAV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1246995:AFR_RS18460 ^@ http://purl.uniprot.org/uniprot/U5W1Y7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18545 ^@ http://purl.uniprot.org/uniprot/U5VY83 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS05985 ^@ http://purl.uniprot.org/uniprot/U5VUZ0 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS40970 ^@ http://purl.uniprot.org/uniprot/U5WB15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1246995:AFR_RS04695 ^@ http://purl.uniprot.org/uniprot/U5VQY4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1246995:AFR_RS38400 ^@ http://purl.uniprot.org/uniprot/U5WD68 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1246995:AFR_RS06450 ^@ http://purl.uniprot.org/uniprot/U5VRV8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1246995:AFR_RS28090 ^@ http://purl.uniprot.org/uniprot/U5W3Z4 ^@ Cofactor ^@ Binds 4 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1246995:AFR_RS03190 ^@ http://purl.uniprot.org/uniprot/U5VPM7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS06865 ^@ http://purl.uniprot.org/uniprot/U5VRR4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS42735 ^@ http://purl.uniprot.org/uniprot/U5WFQ3 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1246995:AFR_RS14625 ^@ http://purl.uniprot.org/uniprot/U5VWF3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS30810 ^@ http://purl.uniprot.org/uniprot/U5W5V4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS22525 ^@ http://purl.uniprot.org/uniprot/U5W0T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS15960 ^@ http://purl.uniprot.org/uniprot/U5VXD8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39850 ^@ http://purl.uniprot.org/uniprot/U5WB17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS05965 ^@ http://purl.uniprot.org/uniprot/U5VR68 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1246995:AFR_RS21880 ^@ http://purl.uniprot.org/uniprot/U5W0I9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S8 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS17200 ^@ http://purl.uniprot.org/uniprot/U5W1B6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS36080 ^@ http://purl.uniprot.org/uniprot/U5WBV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS40370 ^@ http://purl.uniprot.org/uniprot/U5WAW3 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1246995:AFR_RS37055 ^@ http://purl.uniprot.org/uniprot/U5W8W5 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1246995:AFR_RS05520 ^@ http://purl.uniprot.org/uniprot/U5VUH8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1246995:AFR_RS38695 ^@ http://purl.uniprot.org/uniprot/U5W9S1 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1246995:AFR_RS03690 ^@ http://purl.uniprot.org/uniprot/U5VPY7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1246995:AFR_RS28390 ^@ http://purl.uniprot.org/uniprot/U5W455 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS18330 ^@ http://purl.uniprot.org/uniprot/U5W1Q3 ^@ Similarity ^@ Belongs to the peptidase S15 family. http://togogenome.org/gene/1246995:AFR_RS29235 ^@ http://purl.uniprot.org/uniprot/U5W4P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS24570 ^@ http://purl.uniprot.org/uniprot/U5W5G2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS36505 ^@ http://purl.uniprot.org/uniprot/U5W933 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1246995:AFR_RS04940 ^@ http://purl.uniprot.org/uniprot/U5VUF2 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS30660 ^@ http://purl.uniprot.org/uniprot/U5W5S5 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1246995:AFR_RS06890 ^@ http://purl.uniprot.org/uniprot/U5VRR6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1246995:AFR_RS40730 ^@ http://purl.uniprot.org/uniprot/U5WEA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1246995:AFR_RS00020 ^@ http://purl.uniprot.org/uniprot/U5VMU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1246995:AFR_RS10095 ^@ http://purl.uniprot.org/uniprot/U5VTZ8 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS28350 ^@ http://purl.uniprot.org/uniprot/U5W7H7 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS06400 ^@ http://purl.uniprot.org/uniprot/U5VRV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1246995:AFR_RS21320 ^@ http://purl.uniprot.org/uniprot/U5W0E1 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1246995:AFR_RS36865 ^@ http://purl.uniprot.org/uniprot/U5W8Z6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 1 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1246995:AFR_RS11950 ^@ http://purl.uniprot.org/uniprot/U5VUL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS13525 ^@ http://purl.uniprot.org/uniprot/U5VVE0 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS04575 ^@ http://purl.uniprot.org/uniprot/U5VQH1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1246995:AFR_RS11030 ^@ http://purl.uniprot.org/uniprot/U5VXL6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1246995:AFR_RS31590 ^@ http://purl.uniprot.org/uniprot/U5W9B1 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1246995:AFR_RS04690 ^@ http://purl.uniprot.org/uniprot/U5VUA5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1246995:AFR_RS38195 ^@ http://purl.uniprot.org/uniprot/U5W9N4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1246995:AFR_RS00490 ^@ http://purl.uniprot.org/uniprot/U5VRM7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS33230 ^@ http://purl.uniprot.org/uniprot/U5W6U9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS30705 ^@ http://purl.uniprot.org/uniprot/U5W8U9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1246995:AFR_RS10710 ^@ http://purl.uniprot.org/uniprot/U5VXL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1246995:AFR_RS35315 ^@ http://purl.uniprot.org/uniprot/U5W7U7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS09600 ^@ http://purl.uniprot.org/uniprot/U5VX17 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS37930 ^@ http://purl.uniprot.org/uniprot/U5WCY7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS02920 ^@ http://purl.uniprot.org/uniprot/U5VPG7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS32815 ^@ http://purl.uniprot.org/uniprot/U5W9Y4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS32475 ^@ http://purl.uniprot.org/uniprot/U5W6F1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1246995:AFR_RS35135 ^@ http://purl.uniprot.org/uniprot/U5W8B3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS40645 ^@ http://purl.uniprot.org/uniprot/U5WB19 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS09735 ^@ http://purl.uniprot.org/uniprot/U5VTM5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1246995:AFR_RS19450 ^@ http://purl.uniprot.org/uniprot/U5VZD6 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS04765 ^@ http://purl.uniprot.org/uniprot/U5VUB8 ^@ Function ^@ Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1246995:AFR_RS07505 ^@ http://purl.uniprot.org/uniprot/U5VS16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07830 ^@ http://purl.uniprot.org/uniprot/U5VSJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1246995:AFR_RS32870 ^@ http://purl.uniprot.org/uniprot/U5WA40 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1246995:AFR_RS43110 ^@ http://purl.uniprot.org/uniprot/U5WFW1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1246995:AFR_RS14005 ^@ http://purl.uniprot.org/uniprot/U5VVT3 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/1246995:AFR_RS23680 ^@ http://purl.uniprot.org/uniprot/U5W4P9 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS04685 ^@ http://purl.uniprot.org/uniprot/U5VU27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1246995:AFR_RS38265 ^@ http://purl.uniprot.org/uniprot/U5W9H8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAPS reductase family. CysH subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS07340 ^@ http://purl.uniprot.org/uniprot/U5VSA4 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS12005 ^@ http://purl.uniprot.org/uniprot/U5VUY7 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS19625 ^@ http://purl.uniprot.org/uniprot/U5VZG4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS14050 ^@ http://purl.uniprot.org/uniprot/U5VWD3 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1246995:AFR_RS34545 ^@ http://purl.uniprot.org/uniprot/U5W7H0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS01585 ^@ http://purl.uniprot.org/uniprot/U5VSJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS41125 ^@ http://purl.uniprot.org/uniprot/U5WBB5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1246995:AFR_RS01210 ^@ http://purl.uniprot.org/uniprot/U5VS76 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS02100 ^@ http://purl.uniprot.org/uniprot/U5VP21 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1246995:AFR_RS10765 ^@ http://purl.uniprot.org/uniprot/U5VUC4 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1246995:AFR_RS04290 ^@ http://purl.uniprot.org/uniprot/U5VQN6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS17070 ^@ http://purl.uniprot.org/uniprot/U5W133 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16245 ^@ http://purl.uniprot.org/uniprot/U5VWZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05680 ^@ http://purl.uniprot.org/uniprot/U5VRG7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1246995:AFR_RS10185 ^@ http://purl.uniprot.org/uniprot/U5VTV5 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1246995:AFR_RS22585 ^@ http://purl.uniprot.org/uniprot/U5W4B1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1246995:AFR_RS04515 ^@ http://purl.uniprot.org/uniprot/U5VU76 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS08090 ^@ http://purl.uniprot.org/uniprot/U5VW51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37015 ^@ http://purl.uniprot.org/uniprot/U5W9D2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30830 ^@ http://purl.uniprot.org/uniprot/U5W8X8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS21410 ^@ http://purl.uniprot.org/uniprot/U5W3E7 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1246995:AFR_RS42420 ^@ http://purl.uniprot.org/uniprot/U5WCJ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1246995:AFR_RS21135 ^@ http://purl.uniprot.org/uniprot/U5W388 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30780 ^@ http://purl.uniprot.org/uniprot/U5W8W6 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1246995:AFR_RS33275 ^@ http://purl.uniprot.org/uniprot/U5W6W1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS22590 ^@ http://purl.uniprot.org/uniprot/U5W169 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS00340 ^@ http://purl.uniprot.org/uniprot/U5VRJ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS46825 ^@ http://purl.uniprot.org/uniprot/U5W442 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1246995:AFR_RS19705 ^@ http://purl.uniprot.org/uniprot/U5VYY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS15000 ^@ http://purl.uniprot.org/uniprot/U5VZX0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS33065 ^@ http://purl.uniprot.org/uniprot/U5WA31 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1246995:AFR_RS20690 ^@ http://purl.uniprot.org/uniprot/U5W364 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS30980 ^@ http://purl.uniprot.org/uniprot/U5W910 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12105 ^@ http://purl.uniprot.org/uniprot/U5VUN5 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS48100 ^@ http://purl.uniprot.org/uniprot/U5W9K2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1246995:AFR_RS35995 ^@ http://purl.uniprot.org/uniprot/U5W8F0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS14915 ^@ http://purl.uniprot.org/uniprot/U5VW77 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS05270 ^@ http://purl.uniprot.org/uniprot/U5VR94 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1246995:AFR_RS35380 ^@ http://purl.uniprot.org/uniprot/U5WBH1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1246995:AFR_RS40635 ^@ http://purl.uniprot.org/uniprot/U5WBH3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS11305 ^@ http://purl.uniprot.org/uniprot/U5VXR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS20790 ^@ http://purl.uniprot.org/uniprot/U5W383 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1246995:AFR_RS43035 ^@ http://purl.uniprot.org/uniprot/U5WFJ8 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1246995:AFR_RS10825 ^@ http://purl.uniprot.org/uniprot/U5VU83 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1246995:AFR_RS10925 ^@ http://purl.uniprot.org/uniprot/U5VUA0 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS37535 ^@ http://purl.uniprot.org/uniprot/U5W950 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1246995:AFR_RS26820 ^@ http://purl.uniprot.org/uniprot/U5W6K1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS06780 ^@ http://purl.uniprot.org/uniprot/U5VS53 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS23895 ^@ http://purl.uniprot.org/uniprot/U5W188 ^@ Similarity ^@ Belongs to the acetaldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS02995 ^@ http://purl.uniprot.org/uniprot/U5VPI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS22705 ^@ http://purl.uniprot.org/uniprot/U5W473 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1246995:AFR_RS36700 ^@ http://purl.uniprot.org/uniprot/U5WCB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS41640 ^@ http://purl.uniprot.org/uniprot/U5WEW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS09335 ^@ http://purl.uniprot.org/uniprot/U5VT46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS01800 ^@ http://purl.uniprot.org/uniprot/U5VPB9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS14885 ^@ http://purl.uniprot.org/uniprot/U5W003 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS33925 ^@ http://purl.uniprot.org/uniprot/U5W739 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1246995:AFR_RS30230 ^@ http://purl.uniprot.org/uniprot/U5W8L7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS02735 ^@ http://purl.uniprot.org/uniprot/U5VT50 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1246995:AFR_RS02325 ^@ http://purl.uniprot.org/uniprot/U5VP52 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/1246995:AFR_RS36525 ^@ http://purl.uniprot.org/uniprot/U5WC37 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS25355 ^@ http://purl.uniprot.org/uniprot/U5W248 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1246995:AFR_RS18560 ^@ http://purl.uniprot.org/uniprot/U5W205 ^@ Similarity ^@ Belongs to the glycosyl hydrolase. http://togogenome.org/gene/1246995:AFR_RS16205 ^@ http://purl.uniprot.org/uniprot/U5W0J2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1246995:AFR_RS04505 ^@ http://purl.uniprot.org/uniprot/U5VQF9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1246995:AFR_RS02835 ^@ http://purl.uniprot.org/uniprot/U5VT64 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1246995:AFR_RS22365 ^@ http://purl.uniprot.org/uniprot/U5W122 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/1246995:AFR_RS02495 ^@ http://purl.uniprot.org/uniprot/U5VPN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS23670 ^@ http://purl.uniprot.org/uniprot/U5W140 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS19605 ^@ http://purl.uniprot.org/uniprot/U5VYW5 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1246995:AFR_RS24015 ^@ http://purl.uniprot.org/uniprot/U5W218 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS36195 ^@ http://purl.uniprot.org/uniprot/U5W8I7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1246995:AFR_RS29755 ^@ http://purl.uniprot.org/uniprot/U5W599 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1246995:AFR_RS34360 ^@ http://purl.uniprot.org/uniprot/U5WAZ3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1246995:AFR_RS21990 ^@ http://purl.uniprot.org/uniprot/U5W400 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1246995:AFR_RS02250 ^@ http://purl.uniprot.org/uniprot/U5VP39 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. http://togogenome.org/gene/1246995:AFR_RS42105 ^@ http://purl.uniprot.org/uniprot/U5WFE1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS04850 ^@ http://purl.uniprot.org/uniprot/U5VQL4 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1246995:AFR_RS09415 ^@ http://purl.uniprot.org/uniprot/U5VTH5 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1246995:AFR_RS26525 ^@ http://purl.uniprot.org/uniprot/U5W6F2 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the Pup ligase/Pup deamidase family. Pup-conjugating enzyme subfamily.|||Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine.|||The reaction mechanism probably proceeds via the activation of Pup by phosphorylation of its C-terminal glutamate, which is then subject to nucleophilic attack by the substrate lysine, resulting in an isopeptide bond and the release of phosphate as a good leaving group. http://togogenome.org/gene/1246995:AFR_RS35985 ^@ http://purl.uniprot.org/uniprot/U5W8S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39225 ^@ http://purl.uniprot.org/uniprot/U5WAC3 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/1246995:AFR_RS29450 ^@ http://purl.uniprot.org/uniprot/U5W542 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS13290 ^@ http://purl.uniprot.org/uniprot/U5VYW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS29000 ^@ http://purl.uniprot.org/uniprot/U5W7X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS08120 ^@ http://purl.uniprot.org/uniprot/U5VSV2 ^@ Similarity ^@ Belongs to the UPF0045 family. http://togogenome.org/gene/1246995:AFR_RS05630 ^@ http://purl.uniprot.org/uniprot/U5VRF8 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS35430 ^@ http://purl.uniprot.org/uniprot/U5WBI1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS30025 ^@ http://purl.uniprot.org/uniprot/U5W8D6 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS36170 ^@ http://purl.uniprot.org/uniprot/U5W8I2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1246995:AFR_RS05930 ^@ http://purl.uniprot.org/uniprot/U5VUY2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1246995:AFR_RS42190 ^@ http://purl.uniprot.org/uniprot/U5WC01 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. Flotillin subfamily. http://togogenome.org/gene/1246995:AFR_RS37550 ^@ http://purl.uniprot.org/uniprot/U5WCS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1246995:AFR_RS24225 ^@ http://purl.uniprot.org/uniprot/U5W1V7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS10410 ^@ http://purl.uniprot.org/uniprot/U5VXG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1246995:AFR_RS05780 ^@ http://purl.uniprot.org/uniprot/U5VRI5 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1246995:AFR_RS37685 ^@ http://purl.uniprot.org/uniprot/U5W974 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS31680 ^@ http://purl.uniprot.org/uniprot/U5W5X5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1246995:AFR_RS08535 ^@ http://purl.uniprot.org/uniprot/U5VSL0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1246995:AFR_RS23595 ^@ http://purl.uniprot.org/uniprot/U5W123 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS03960 ^@ http://purl.uniprot.org/uniprot/U5VQ78 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Belongs to the glycosyltransferase 2 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS12285 ^@ http://purl.uniprot.org/uniprot/U5VUQ9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS30610 ^@ http://purl.uniprot.org/uniprot/U5W5R7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1246995:AFR_RS29620 ^@ http://purl.uniprot.org/uniprot/U5W8B1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS24500 ^@ http://purl.uniprot.org/uniprot/U5W2A0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04480 ^@ http://purl.uniprot.org/uniprot/U5VQF6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1246995:AFR_RS27805 ^@ http://purl.uniprot.org/uniprot/U5W3T8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS13945 ^@ http://purl.uniprot.org/uniprot/U5VZJ0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS01515 ^@ http://purl.uniprot.org/uniprot/U5VP57 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1246995:AFR_RS02575 ^@ http://purl.uniprot.org/uniprot/U5VPR5 ^@ Similarity ^@ Belongs to the WXG100 family. http://togogenome.org/gene/1246995:AFR_RS07635 ^@ http://purl.uniprot.org/uniprot/U5VS36 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1246995:AFR_RS37875 ^@ http://purl.uniprot.org/uniprot/U5WCR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0060 family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS19330 ^@ http://purl.uniprot.org/uniprot/U5VYS6 ^@ Cofactor|||PTM|||Similarity ^@ Belongs to the copper/topaquinone oxidase family.|||Contains 1 topaquinone per subunit.|||Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. http://togogenome.org/gene/1246995:AFR_RS12000 ^@ http://purl.uniprot.org/uniprot/U5VUM1 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS10230 ^@ http://purl.uniprot.org/uniprot/U5VTW3 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1246995:AFR_RS37880 ^@ http://purl.uniprot.org/uniprot/U5WCX9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS09370 ^@ http://purl.uniprot.org/uniprot/U5VWQ5 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS04905 ^@ http://purl.uniprot.org/uniprot/U5VQY6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1246995:AFR_RS40600 ^@ http://purl.uniprot.org/uniprot/U5WE78 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1246995:AFR_RS05150 ^@ http://purl.uniprot.org/uniprot/U5VQR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1246995:AFR_RS05585 ^@ http://purl.uniprot.org/uniprot/U5VQZ2 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1246995:AFR_RS41430 ^@ http://purl.uniprot.org/uniprot/U5WBB3 ^@ Similarity ^@ Belongs to the homogentisate dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS03500 ^@ http://purl.uniprot.org/uniprot/U5VTB5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS41485 ^@ http://purl.uniprot.org/uniprot/U5WBI4 ^@ Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). http://togogenome.org/gene/1246995:AFR_RS33475 ^@ http://purl.uniprot.org/uniprot/U5W6U1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS39825 ^@ http://purl.uniprot.org/uniprot/U5WB12 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS31065 ^@ http://purl.uniprot.org/uniprot/U5W5F4 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1246995:AFR_RS42830 ^@ http://purl.uniprot.org/uniprot/U5WFG1 ^@ Similarity|||Subunit ^@ Belongs to the Bpa family.|||Forms a homooligomeric, either hexameric or heptameric, ring-like structure which stacks co-axially with the proteasomal alpha-rings. http://togogenome.org/gene/1246995:AFR_RS11760 ^@ http://purl.uniprot.org/uniprot/U5VYA6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS07035 ^@ http://purl.uniprot.org/uniprot/U5VRT8 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1246995:AFR_RS10005 ^@ http://purl.uniprot.org/uniprot/U5VTE9 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS08295 ^@ http://purl.uniprot.org/uniprot/U5VSF4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12965 ^@ http://purl.uniprot.org/uniprot/U5VYQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS38080 ^@ http://purl.uniprot.org/uniprot/U5WD13 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1246995:AFR_RS20435 ^@ http://purl.uniprot.org/uniprot/U5W2V8 ^@ Function|||Similarity ^@ Belongs to the Stf0 sulfotransferase family.|||Catalyzes the sulfuryl group transfer from 3'-phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). http://togogenome.org/gene/1246995:AFR_RS05200 ^@ http://purl.uniprot.org/uniprot/U5VQS3 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS00730 ^@ http://purl.uniprot.org/uniprot/U5VNQ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1246995:AFR_RS07715 ^@ http://purl.uniprot.org/uniprot/U5VVY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1246995:AFR_RS36375 ^@ http://purl.uniprot.org/uniprot/U5WC14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS07580 ^@ http://purl.uniprot.org/uniprot/U5VSE7 ^@ Similarity|||Subunit ^@ Belongs to the acetyltransferase Eis family.|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1246995:AFR_RS38025 ^@ http://purl.uniprot.org/uniprot/U5WCT8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1246995:AFR_RS26660 ^@ http://purl.uniprot.org/uniprot/U5W3I6 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1246995:AFR_RS39750 ^@ http://purl.uniprot.org/uniprot/U5WAZ5 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS18220 ^@ http://purl.uniprot.org/uniprot/U5VY16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS24670 ^@ http://purl.uniprot.org/uniprot/U5W5H9 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1246995:AFR_RS07945 ^@ http://purl.uniprot.org/uniprot/U5VSR9 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1246995:AFR_RS17955 ^@ http://purl.uniprot.org/uniprot/U5VY70 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS30170 ^@ http://purl.uniprot.org/uniprot/U5W543 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS23410 ^@ http://purl.uniprot.org/uniprot/U5W4J8 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS43195 ^@ http://purl.uniprot.org/uniprot/U5WCY8 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1246995:AFR_RS36710 ^@ http://purl.uniprot.org/uniprot/U5W8R5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1246995:AFR_RS40250 ^@ http://purl.uniprot.org/uniprot/U5WE15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer.|||In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.|||In the N-terminal section; belongs to the MIP18 family. http://togogenome.org/gene/1246995:AFR_RS27900 ^@ http://purl.uniprot.org/uniprot/U5W3M1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS01770 ^@ http://purl.uniprot.org/uniprot/U5VNW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS09000 ^@ http://purl.uniprot.org/uniprot/U5VWJ7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1246995:AFR_RS08020 ^@ http://purl.uniprot.org/uniprot/U5VST3 ^@ Similarity ^@ Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family. http://togogenome.org/gene/1246995:AFR_RS04805 ^@ http://purl.uniprot.org/uniprot/U5VQW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS21525 ^@ http://purl.uniprot.org/uniprot/U5W0N4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS40060 ^@ http://purl.uniprot.org/uniprot/U5WB60 ^@ Similarity ^@ Belongs to the cyclic nucleotide phosphodiesterase class-III family. http://togogenome.org/gene/1246995:AFR_RS34155 ^@ http://purl.uniprot.org/uniprot/U5W7H3 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS11595 ^@ http://purl.uniprot.org/uniprot/U5VUF8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS01885 ^@ http://purl.uniprot.org/uniprot/U5VSQ0 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS22250 ^@ http://purl.uniprot.org/uniprot/U5W0P0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS27915 ^@ http://purl.uniprot.org/uniprot/U5W796 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS12655 ^@ http://purl.uniprot.org/uniprot/U5VUX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS42140 ^@ http://purl.uniprot.org/uniprot/U5WBZ1 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/1246995:AFR_RS28070 ^@ http://purl.uniprot.org/uniprot/U5W7C4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS03820 ^@ http://purl.uniprot.org/uniprot/U5VTM8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS08070 ^@ http://purl.uniprot.org/uniprot/U5VSU1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS17175 ^@ http://purl.uniprot.org/uniprot/U5W1B3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS29395 ^@ http://purl.uniprot.org/uniprot/U5W869 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS22570 ^@ http://purl.uniprot.org/uniprot/U5W0J9 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1246995:AFR_RS10520 ^@ http://purl.uniprot.org/uniprot/U5VTP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS16100 ^@ http://purl.uniprot.org/uniprot/U5W0H3 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS01390 ^@ http://purl.uniprot.org/uniprot/U5VP38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS09315 ^@ http://purl.uniprot.org/uniprot/U5VTF8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS06060 ^@ http://purl.uniprot.org/uniprot/U5VV05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS20065 ^@ http://purl.uniprot.org/uniprot/U5W2V6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS33060 ^@ http://purl.uniprot.org/uniprot/U5W6R0 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1246995:AFR_RS25945 ^@ http://purl.uniprot.org/uniprot/U5W2G0 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/1246995:AFR_RS07570 ^@ http://purl.uniprot.org/uniprot/U5VSJ4 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1246995:AFR_RS21795 ^@ http://purl.uniprot.org/uniprot/U5W3W2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS36775 ^@ http://purl.uniprot.org/uniprot/U5WCD5 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1246995:AFR_RS20620 ^@ http://purl.uniprot.org/uniprot/U5W008 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS08505 ^@ http://purl.uniprot.org/uniprot/U5VT34 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1246995:AFR_RS21875 ^@ http://purl.uniprot.org/uniprot/U5W082 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Vgb family.|||Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS39900 ^@ http://purl.uniprot.org/uniprot/U5WB28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1246995:AFR_RS05825 ^@ http://purl.uniprot.org/uniprot/U5VUW1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the DyP-type peroxidase family.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group non-covalently per subunit.|||Involved in the recovery of exogenous heme iron. Extracts iron from heme while preserving the protoporphyrin ring intact. http://togogenome.org/gene/1246995:AFR_RS24085 ^@ http://purl.uniprot.org/uniprot/U5W572 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS19015 ^@ http://purl.uniprot.org/uniprot/U5W2B9 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 2 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1246995:AFR_RS09060 ^@ http://purl.uniprot.org/uniprot/U5VTH6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS25490 ^@ http://purl.uniprot.org/uniprot/U5W2H4 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family.|||Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09500 ^@ http://purl.uniprot.org/uniprot/U5VWZ8 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1246995:AFR_RS10665 ^@ http://purl.uniprot.org/uniprot/U5VUA6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS42685 ^@ http://purl.uniprot.org/uniprot/U5WFP4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS07625 ^@ http://purl.uniprot.org/uniprot/U5VVX0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1246995:AFR_RS43215 ^@ http://purl.uniprot.org/uniprot/U5WFX6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1246995:AFR_RS31210 ^@ http://purl.uniprot.org/uniprot/U5W635 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1246995:AFR_RS36545 ^@ http://purl.uniprot.org/uniprot/U5WC10 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1246995:AFR_RS30740 ^@ http://purl.uniprot.org/uniprot/U5W583 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1246995:AFR_RS27370 ^@ http://purl.uniprot.org/uniprot/U5W6V0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1246995:AFR_RS06255 ^@ http://purl.uniprot.org/uniprot/U5VUW3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS19035 ^@ http://purl.uniprot.org/uniprot/U5W266 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1246995:AFR_RS05865 ^@ http://purl.uniprot.org/uniprot/U5VRG1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1246995:AFR_RS38340 ^@ http://purl.uniprot.org/uniprot/U5W9R4 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1246995:AFR_RS21290 ^@ http://purl.uniprot.org/uniprot/U5W3I0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS31135 ^@ http://purl.uniprot.org/uniprot/U5W616 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS26360 ^@ http://purl.uniprot.org/uniprot/U5W3B2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1246995:AFR_RS27230 ^@ http://purl.uniprot.org/uniprot/U5W3T6 ^@ Similarity|||Subunit ^@ Belongs to the aminoglycoside phosphotransferase family.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS30250 ^@ http://purl.uniprot.org/uniprot/U5W8H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS22685 ^@ http://purl.uniprot.org/uniprot/U5W4C6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS06050 ^@ http://purl.uniprot.org/uniprot/U5VRJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS41370 ^@ http://purl.uniprot.org/uniprot/U5WBW5 ^@ Function|||Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.|||May catalyze the transamination reaction in phenylalanine biosynthesis. http://togogenome.org/gene/1246995:AFR_RS06245 ^@ http://purl.uniprot.org/uniprot/U5VRC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS34475 ^@ http://purl.uniprot.org/uniprot/U5W7M6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS26260 ^@ http://purl.uniprot.org/uniprot/U5W6A9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS20605 ^@ http://purl.uniprot.org/uniprot/U5VZP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39655 ^@ http://purl.uniprot.org/uniprot/U5WAD3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1246995:AFR_RS03965 ^@ http://purl.uniprot.org/uniprot/U5VQI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS29390 ^@ http://purl.uniprot.org/uniprot/U5W818 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS12760 ^@ http://purl.uniprot.org/uniprot/U5VVB7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS31645 ^@ http://purl.uniprot.org/uniprot/U5W9I1 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/1246995:AFR_RS37405 ^@ http://purl.uniprot.org/uniprot/U5W9J9 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1246995:AFR_RS18795 ^@ http://purl.uniprot.org/uniprot/U5VYE4 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS12795 ^@ http://purl.uniprot.org/uniprot/U5VYT1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07220 ^@ http://purl.uniprot.org/uniprot/U5VVP9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07455 ^@ http://purl.uniprot.org/uniprot/U5VS04 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS02305 ^@ http://purl.uniprot.org/uniprot/U5VPK9 ^@ Similarity ^@ Belongs to the CDP-glycerol glycerophosphotransferase family. http://togogenome.org/gene/1246995:AFR_RS25940 ^@ http://purl.uniprot.org/uniprot/U5W329 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1246995:AFR_RS19610 ^@ http://purl.uniprot.org/uniprot/U5VZ66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS13630 ^@ http://purl.uniprot.org/uniprot/U5VVU2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS27845 ^@ http://purl.uniprot.org/uniprot/U5W459 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS25755 ^@ http://purl.uniprot.org/uniprot/U5W5V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS29745 ^@ http://purl.uniprot.org/uniprot/U5W886 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1246995:AFR_RS03510 ^@ http://purl.uniprot.org/uniprot/U5VQ89 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1246995:AFR_RS39555 ^@ http://purl.uniprot.org/uniprot/U5WAB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS24810 ^@ http://purl.uniprot.org/uniprot/U5W246 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS01440 ^@ http://purl.uniprot.org/uniprot/U5VP44 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS42100 ^@ http://purl.uniprot.org/uniprot/U5WF30 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/1246995:AFR_RS16025 ^@ http://purl.uniprot.org/uniprot/U5W0F9 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1246995:AFR_RS06485 ^@ http://purl.uniprot.org/uniprot/U5VVC7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS31230 ^@ http://purl.uniprot.org/uniprot/U5W959 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS37645 ^@ http://purl.uniprot.org/uniprot/U5WCL4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS36320 ^@ http://purl.uniprot.org/uniprot/U5W8L3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1246995:AFR_RS26665 ^@ http://purl.uniprot.org/uniprot/U5W2Z6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS22560 ^@ http://purl.uniprot.org/uniprot/U5W4A7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16825 ^@ http://purl.uniprot.org/uniprot/U5W149 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS27105 ^@ http://purl.uniprot.org/uniprot/U5W6V5 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1246995:AFR_RS31265 ^@ http://purl.uniprot.org/uniprot/U5W5K1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Catalyzes the conjugation of the 1'-hydroxyl group of D-myo-inositol-3-phosphate (also named L-myo-inositol-1-phosphate) with a lipid tail of cytidine diphosphate diacylglycerol (CDP-DAG), forming phosphatidylinositol phosphate (PIP) and CMP. PIP is a precursor of phosphatidylinositol (PI) which is an essential lipid required for cell wall formation.|||Cell membrane|||Contains a di-nuclear catalytic Mg(2+) center.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS00005 ^@ http://purl.uniprot.org/uniprot/U5VRE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1246995:AFR_RS32270 ^@ http://purl.uniprot.org/uniprot/U5W6C2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12425 ^@ http://purl.uniprot.org/uniprot/U5VVB6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS43895 ^@ http://purl.uniprot.org/uniprot/U5W2N4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1246995:AFR_RS25840 ^@ http://purl.uniprot.org/uniprot/U5W308 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1246995:AFR_RS06425 ^@ http://purl.uniprot.org/uniprot/U5VRV4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1246995:AFR_RS19020 ^@ http://purl.uniprot.org/uniprot/U5VZ77 ^@ Similarity ^@ Belongs to the transglycosylase family. Rpf subfamily. http://togogenome.org/gene/1246995:AFR_RS01745 ^@ http://purl.uniprot.org/uniprot/U5VNW4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS17770 ^@ http://purl.uniprot.org/uniprot/U5VY38 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 42 family. http://togogenome.org/gene/1246995:AFR_RS09975 ^@ http://purl.uniprot.org/uniprot/U5VTX4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS11740 ^@ http://purl.uniprot.org/uniprot/U5VV01 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS39495 ^@ http://purl.uniprot.org/uniprot/U5WDM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS41400 ^@ http://purl.uniprot.org/uniprot/U5WBA7 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS16240 ^@ http://purl.uniprot.org/uniprot/U5VXI9 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1246995:AFR_RS18840 ^@ http://purl.uniprot.org/uniprot/U5W201 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS18650 ^@ http://purl.uniprot.org/uniprot/U5VYK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS31185 ^@ http://purl.uniprot.org/uniprot/U5W627 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1246995:AFR_RS39315 ^@ http://purl.uniprot.org/uniprot/U5WAR0 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1246995:AFR_RS04655 ^@ http://purl.uniprot.org/uniprot/U5VQU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS44280 ^@ http://purl.uniprot.org/uniprot/U5WBS5 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS04540 ^@ http://purl.uniprot.org/uniprot/U5VU81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1246995:AFR_RS33090 ^@ http://purl.uniprot.org/uniprot/U5WA35 ^@ Similarity ^@ Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family. http://togogenome.org/gene/1246995:AFR_RS19555 ^@ http://purl.uniprot.org/uniprot/U5VYV8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS21190 ^@ http://purl.uniprot.org/uniprot/U5W3G1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS20555 ^@ http://purl.uniprot.org/uniprot/U5VZN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS38550 ^@ http://purl.uniprot.org/uniprot/U5WD27 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1246995:AFR_RS16680 ^@ http://purl.uniprot.org/uniprot/U5VXM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS22660 ^@ http://purl.uniprot.org/uniprot/U5W4C3 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1246995:AFR_RS00765 ^@ http://purl.uniprot.org/uniprot/U5VNR8 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1246995:AFR_RS42380 ^@ http://purl.uniprot.org/uniprot/U5WCJ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18150 ^@ http://purl.uniprot.org/uniprot/U5VYB1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/1246995:AFR_RS20120 ^@ http://purl.uniprot.org/uniprot/U5VZR7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS04405 ^@ http://purl.uniprot.org/uniprot/U5VQT2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS07785 ^@ http://purl.uniprot.org/uniprot/U5VVS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1246995:AFR_RS03400 ^@ http://purl.uniprot.org/uniprot/U5VT99 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS00575 ^@ http://purl.uniprot.org/uniprot/U5VNM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1246995:AFR_RS22320 ^@ http://purl.uniprot.org/uniprot/U5W0F6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS18355 ^@ http://purl.uniprot.org/uniprot/U5W1Q8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS30850 ^@ http://purl.uniprot.org/uniprot/U5W8S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1246995:AFR_RS27460 ^@ http://purl.uniprot.org/uniprot/U5W6X0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS40425 ^@ http://purl.uniprot.org/uniprot/U5WE45 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS05910 ^@ http://purl.uniprot.org/uniprot/U5VRL0 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF2.|||Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. http://togogenome.org/gene/1246995:AFR_RS13840 ^@ http://purl.uniprot.org/uniprot/U5VZE4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1246995:AFR_RS23215 ^@ http://purl.uniprot.org/uniprot/U5W4L9 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS30390 ^@ http://purl.uniprot.org/uniprot/U5W513 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1246995:AFR_RS08000 ^@ http://purl.uniprot.org/uniprot/U5VS98 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1246995:AFR_RS41510 ^@ http://purl.uniprot.org/uniprot/U5WBI9 ^@ Similarity ^@ Belongs to the DszC flavin monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS01255 ^@ http://purl.uniprot.org/uniprot/U5VS17 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS41375 ^@ http://purl.uniprot.org/uniprot/U5WBA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS33915 ^@ http://purl.uniprot.org/uniprot/U5WAN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS10600 ^@ http://purl.uniprot.org/uniprot/U5VU40 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1246995:AFR_RS36660 ^@ http://purl.uniprot.org/uniprot/U5W8Q6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1246995:AFR_RS00735 ^@ http://purl.uniprot.org/uniprot/U5VN83 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1246995:AFR_RS00540 ^@ http://purl.uniprot.org/uniprot/U5VRN8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1246995:AFR_RS39170 ^@ http://purl.uniprot.org/uniprot/U5WA51 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09105 ^@ http://purl.uniprot.org/uniprot/U5VWT1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS35960 ^@ http://purl.uniprot.org/uniprot/U5W8S0 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1246995:AFR_RS05070 ^@ http://purl.uniprot.org/uniprot/U5VR54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS24455 ^@ http://purl.uniprot.org/uniprot/U5W1Z5 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS32770 ^@ http://purl.uniprot.org/uniprot/U5WA25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SsgA family.|||Cell septum http://togogenome.org/gene/1246995:AFR_RS33890 ^@ http://purl.uniprot.org/uniprot/U5WAM6 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1246995:AFR_RS31105 ^@ http://purl.uniprot.org/uniprot/U5W937 ^@ Function|||Similarity ^@ Belongs to the peptidase S51 family.|||Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides. http://togogenome.org/gene/1246995:AFR_RS40670 ^@ http://purl.uniprot.org/uniprot/U5WAU8 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/1246995:AFR_RS26560 ^@ http://purl.uniprot.org/uniprot/U5W3G9 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1246995:AFR_RS37275 ^@ http://purl.uniprot.org/uniprot/U5WCM3 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1246995:AFR_RS09145 ^@ http://purl.uniprot.org/uniprot/U5VTI5 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS14490 ^@ http://purl.uniprot.org/uniprot/U5VWK2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS14085 ^@ http://purl.uniprot.org/uniprot/U5VW71 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS10075 ^@ http://purl.uniprot.org/uniprot/U5VTG5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1246995:AFR_RS27580 ^@ http://purl.uniprot.org/uniprot/U5W3P3 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS39715 ^@ http://purl.uniprot.org/uniprot/U5WDR2 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS19575 ^@ http://purl.uniprot.org/uniprot/U5VZF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS30890 ^@ http://purl.uniprot.org/uniprot/U5W5B5 ^@ Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily. http://togogenome.org/gene/1246995:AFR_RS23870 ^@ http://purl.uniprot.org/uniprot/U5W1W0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS24380 ^@ http://purl.uniprot.org/uniprot/U5W564 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS10675 ^@ http://purl.uniprot.org/uniprot/U5VU55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1246995:AFR_RS04635 ^@ http://purl.uniprot.org/uniprot/U5VU17 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1246995:AFR_RS08835 ^@ http://purl.uniprot.org/uniprot/U5VSU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS21405 ^@ http://purl.uniprot.org/uniprot/U5W057 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1246995:AFR_RS30595 ^@ http://purl.uniprot.org/uniprot/U5W5C5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1246995:AFR_RS16690 ^@ http://purl.uniprot.org/uniprot/U5W134 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1246995:AFR_RS11145 ^@ http://purl.uniprot.org/uniprot/U5VU24 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1246995:AFR_RS19715 ^@ http://purl.uniprot.org/uniprot/U5W2H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS01750 ^@ http://purl.uniprot.org/uniprot/U5VPB1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS01725 ^@ http://purl.uniprot.org/uniprot/U5VPA6 ^@ Similarity ^@ Belongs to the complex I 24 kDa subunit family. http://togogenome.org/gene/1246995:AFR_RS10590 ^@ http://purl.uniprot.org/uniprot/U5VU94 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS20430 ^@ http://purl.uniprot.org/uniprot/U5VZK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1246995:AFR_RS25670 ^@ http://purl.uniprot.org/uniprot/U5W2L1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37255 ^@ http://purl.uniprot.org/uniprot/U5W9G9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1246995:AFR_RS39980 ^@ http://purl.uniprot.org/uniprot/U5WB45 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1246995:AFR_RS02970 ^@ http://purl.uniprot.org/uniprot/U5VPH8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS31195 ^@ http://purl.uniprot.org/uniprot/U5W5Q4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1246995:AFR_RS39660 ^@ http://purl.uniprot.org/uniprot/U5WAK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39670 ^@ http://purl.uniprot.org/uniprot/U5WE04 ^@ Similarity ^@ Belongs to the CDP-glycerol glycerophosphotransferase family. http://togogenome.org/gene/1246995:AFR_RS15340 ^@ http://purl.uniprot.org/uniprot/U5VWF2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS13400 ^@ http://purl.uniprot.org/uniprot/U5VVW2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS26475 ^@ http://purl.uniprot.org/uniprot/U5W6A8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1246995:AFR_RS04315 ^@ http://purl.uniprot.org/uniprot/U5VQN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS41115 ^@ http://purl.uniprot.org/uniprot/U5WBR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS44340 ^@ http://purl.uniprot.org/uniprot/U5WDA9 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1246995:AFR_RS24065 ^@ http://purl.uniprot.org/uniprot/U5W232 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS35080 ^@ http://purl.uniprot.org/uniprot/U5WBC0 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS27045 ^@ http://purl.uniprot.org/uniprot/U5W3F3 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and hydrogenobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of hydrogenobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CobB catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1246995:AFR_RS04275 ^@ http://purl.uniprot.org/uniprot/U5VU37 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1246995:AFR_RS13165 ^@ http://purl.uniprot.org/uniprot/U5VYU5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS31015 ^@ http://purl.uniprot.org/uniprot/U5W5E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS00330 ^@ http://purl.uniprot.org/uniprot/U5VMZ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrgA family.|||Cell membrane|||Involved in cell division. http://togogenome.org/gene/1246995:AFR_RS36155 ^@ http://purl.uniprot.org/uniprot/U5WBW6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1246995:AFR_RS38055 ^@ http://purl.uniprot.org/uniprot/U5WD09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1246995:AFR_RS41555 ^@ http://purl.uniprot.org/uniprot/U5WBE0 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1246995:AFR_RS38105 ^@ http://purl.uniprot.org/uniprot/U5WD17 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1246995:AFR_RS05580 ^@ http://purl.uniprot.org/uniprot/U5VRF1 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/1246995:AFR_RS23330 ^@ http://purl.uniprot.org/uniprot/U5W185 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS11175 ^@ http://purl.uniprot.org/uniprot/U5VU30 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1246995:AFR_RS00720 ^@ http://purl.uniprot.org/uniprot/U5VRR9 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1246995:AFR_RS30295 ^@ http://purl.uniprot.org/uniprot/U5W565 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS41635 ^@ http://purl.uniprot.org/uniprot/U5WBN5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS40685 ^@ http://purl.uniprot.org/uniprot/U5WEH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS20520 ^@ http://purl.uniprot.org/uniprot/U5VZZ1 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS34715 ^@ http://purl.uniprot.org/uniprot/U5WB54 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS09075 ^@ http://purl.uniprot.org/uniprot/U5VWK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS28840 ^@ http://purl.uniprot.org/uniprot/U5W4D2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS06080 ^@ http://purl.uniprot.org/uniprot/U5VUS7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS19865 ^@ http://purl.uniprot.org/uniprot/U5W2S3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS31220 ^@ http://purl.uniprot.org/uniprot/U5W5Q8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1246995:AFR_RS05120 ^@ http://purl.uniprot.org/uniprot/U5VR64 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1246995:AFR_RS32430 ^@ http://purl.uniprot.org/uniprot/U5W9R2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1246995:AFR_RS14855 ^@ http://purl.uniprot.org/uniprot/U5VZU1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 11 (cellulase G) family. http://togogenome.org/gene/1246995:AFR_RS36165 ^@ http://purl.uniprot.org/uniprot/U5W8B5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1246995:AFR_RS41750 ^@ http://purl.uniprot.org/uniprot/U5WC76 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1246995:AFR_RS21480 ^@ http://purl.uniprot.org/uniprot/U5W075 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS14720 ^@ http://purl.uniprot.org/uniprot/U5VW47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS01765 ^@ http://purl.uniprot.org/uniprot/U5VPA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS11635 ^@ http://purl.uniprot.org/uniprot/U5VY84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS02160 ^@ http://purl.uniprot.org/uniprot/U5VSL9 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1246995:AFR_RS40710 ^@ http://purl.uniprot.org/uniprot/U5WEI3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS42950 ^@ http://purl.uniprot.org/uniprot/U5WCB5 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1246995:AFR_RS19150 ^@ http://purl.uniprot.org/uniprot/U5VYQ2 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS10260 ^@ http://purl.uniprot.org/uniprot/U5VX67 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1246995:AFR_RS30340 ^@ http://purl.uniprot.org/uniprot/U5W504 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS42010 ^@ http://purl.uniprot.org/uniprot/U5WBX2 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1246995:AFR_RS21935 ^@ http://purl.uniprot.org/uniprot/U5W3S0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS11195 ^@ http://purl.uniprot.org/uniprot/U5VUL0 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1246995:AFR_RS22645 ^@ http://purl.uniprot.org/uniprot/U5W0L2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1246995:AFR_RS39820 ^@ http://purl.uniprot.org/uniprot/U5WE31 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS31165 ^@ http://purl.uniprot.org/uniprot/U5W5H7 ^@ Similarity|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS42005 ^@ http://purl.uniprot.org/uniprot/U5WBQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS40380 ^@ http://purl.uniprot.org/uniprot/U5WEC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1246995:AFR_RS07265 ^@ http://purl.uniprot.org/uniprot/U5VVJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS30725 ^@ http://purl.uniprot.org/uniprot/U5W8Q7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1246995:AFR_RS11355 ^@ http://purl.uniprot.org/uniprot/U5VXW7 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS39865 ^@ http://purl.uniprot.org/uniprot/U5WDU2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 51 family. http://togogenome.org/gene/1246995:AFR_RS38270 ^@ http://purl.uniprot.org/uniprot/U5WCY1 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/1246995:AFR_RS30955 ^@ http://purl.uniprot.org/uniprot/U5W903 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS09710 ^@ http://purl.uniprot.org/uniprot/U5VTL9 ^@ Caution|||Cofactor|||Function|||Subunit ^@ Binds 1 Mg(2+) ion per subunit.|||Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS20580 ^@ http://purl.uniprot.org/uniprot/U5VZN7 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/1246995:AFR_RS34020 ^@ http://purl.uniprot.org/uniprot/U5W7P9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS02960 ^@ http://purl.uniprot.org/uniprot/U5VT85 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16445 ^@ http://purl.uniprot.org/uniprot/U5VXI3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS39580 ^@ http://purl.uniprot.org/uniprot/U5WAB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS11990 ^@ http://purl.uniprot.org/uniprot/U5VYE5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1246995:AFR_RS22060 ^@ http://purl.uniprot.org/uniprot/U5W3U5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05040 ^@ http://purl.uniprot.org/uniprot/U5VUH2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05035 ^@ http://purl.uniprot.org/uniprot/U5VU90 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS17855 ^@ http://purl.uniprot.org/uniprot/U5W1G6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS16555 ^@ http://purl.uniprot.org/uniprot/U5W109 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1246995:AFR_RS13010 ^@ http://purl.uniprot.org/uniprot/U5VVH1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS22505 ^@ http://purl.uniprot.org/uniprot/U5W432 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS24195 ^@ http://purl.uniprot.org/uniprot/U5W1K4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS21240 ^@ http://purl.uniprot.org/uniprot/U5W3H0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sbp family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS29405 ^@ http://purl.uniprot.org/uniprot/U5W4J1 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1246995:AFR_RS15840 ^@ http://purl.uniprot.org/uniprot/U5VWQ1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS27750 ^@ http://purl.uniprot.org/uniprot/U5W3J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39000 ^@ http://purl.uniprot.org/uniprot/U5WA42 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1246995:AFR_RS06710 ^@ http://purl.uniprot.org/uniprot/U5VRP0 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS13040 ^@ http://purl.uniprot.org/uniprot/U5VYS2 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS20205 ^@ http://purl.uniprot.org/uniprot/U5VZG3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS20615 ^@ http://purl.uniprot.org/uniprot/U5W352 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS34595 ^@ http://purl.uniprot.org/uniprot/U5W7H9 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/1246995:AFR_RS43660 ^@ http://purl.uniprot.org/uniprot/U5W0G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS22890 ^@ http://purl.uniprot.org/uniprot/U5W1C5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1246995:AFR_RS07915 ^@ http://purl.uniprot.org/uniprot/U5VW18 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39485 ^@ http://purl.uniprot.org/uniprot/U5WAA3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS37485 ^@ http://purl.uniprot.org/uniprot/U5W944 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS07630 ^@ http://purl.uniprot.org/uniprot/U5VSK5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1246995:AFR_RS41315 ^@ http://purl.uniprot.org/uniprot/U5WEV2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS32525 ^@ http://purl.uniprot.org/uniprot/U5W6B2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS07235 ^@ http://purl.uniprot.org/uniprot/U5VS87 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS42415 ^@ http://purl.uniprot.org/uniprot/U5WFJ4 ^@ Caution|||Similarity ^@ Belongs to the globin family. Two-domain flavohemoproteins subfamily.|||In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS33440 ^@ http://purl.uniprot.org/uniprot/U5WAE4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1246995:AFR_RS32655 ^@ http://purl.uniprot.org/uniprot/U5W6I2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS31795 ^@ http://purl.uniprot.org/uniprot/U5W9K7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS04210 ^@ http://purl.uniprot.org/uniprot/U5VQC0 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/1246995:AFR_RS04830 ^@ http://purl.uniprot.org/uniprot/U5VQX1 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS04630 ^@ http://purl.uniprot.org/uniprot/U5VQT7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1246995:AFR_RS30940 ^@ http://purl.uniprot.org/uniprot/U5W5C6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS00530 ^@ http://purl.uniprot.org/uniprot/U5VN38 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1246995:AFR_RS36100 ^@ http://purl.uniprot.org/uniprot/U5WBR2 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1246995:AFR_RS03160 ^@ http://purl.uniprot.org/uniprot/U5VQ22 ^@ Similarity ^@ Belongs to the LOR family. http://togogenome.org/gene/1246995:AFR_RS11295 ^@ http://purl.uniprot.org/uniprot/U5VU58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS01705 ^@ http://purl.uniprot.org/uniprot/U5VSD4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS30855 ^@ http://purl.uniprot.org/uniprot/U5W8Y4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS15170 ^@ http://purl.uniprot.org/uniprot/U5VWP8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS36380 ^@ http://purl.uniprot.org/uniprot/U5W904 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1246995:AFR_RS34705 ^@ http://purl.uniprot.org/uniprot/U5W7R4 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS37360 ^@ http://purl.uniprot.org/uniprot/U5W920 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1246995:AFR_RS23425 ^@ http://purl.uniprot.org/uniprot/U5W0Y4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic Ku family.|||Homodimer. Interacts with LigD.|||With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. http://togogenome.org/gene/1246995:AFR_RS47550 ^@ http://purl.uniprot.org/uniprot/U5W9X4 ^@ Cofactor|||Function ^@ Binds 1 [3Fe-4S] cluster.|||Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1246995:AFR_RS20795 ^@ http://purl.uniprot.org/uniprot/U5W040 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS06570 ^@ http://purl.uniprot.org/uniprot/U5VS23 ^@ Function|||Subcellular Location Annotation ^@ Cell membrane|||May be specifically involved in the processing, transport, and/or maturation of the MADH beta-subunit.|||Membrane http://togogenome.org/gene/1246995:AFR_RS33130 ^@ http://purl.uniprot.org/uniprot/U5W6L2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS06370 ^@ http://purl.uniprot.org/uniprot/U5VRI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS28430 ^@ http://purl.uniprot.org/uniprot/U5W4H8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Set transporter family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS09740 ^@ http://purl.uniprot.org/uniprot/U5VWX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS08065 ^@ http://purl.uniprot.org/uniprot/U5VW46 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1246995:AFR_RS43045 ^@ http://purl.uniprot.org/uniprot/U5WCW5 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1246995:AFR_RS25110 ^@ http://purl.uniprot.org/uniprot/U5W2A1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1246995:AFR_RS05310 ^@ http://purl.uniprot.org/uniprot/U5VUD6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1246995:AFR_RS09280 ^@ http://purl.uniprot.org/uniprot/U5VTK6 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1246995:AFR_RS35765 ^@ http://purl.uniprot.org/uniprot/U5W829 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS16945 ^@ http://purl.uniprot.org/uniprot/U5W110 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS17330 ^@ http://purl.uniprot.org/uniprot/U5VY58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS24580 ^@ http://purl.uniprot.org/uniprot/U5W1R0 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS18970 ^@ http://purl.uniprot.org/uniprot/U5VYJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS42205 ^@ http://purl.uniprot.org/uniprot/U5WCF7 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1246995:AFR_RS04770 ^@ http://purl.uniprot.org/uniprot/U5VQZ9 ^@ Function ^@ Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P. http://togogenome.org/gene/1246995:AFR_RS00645 ^@ http://purl.uniprot.org/uniprot/U5VRQ6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class II fructose-bisphosphate aldolase family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.|||Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. http://togogenome.org/gene/1246995:AFR_RS36395 ^@ http://purl.uniprot.org/uniprot/U5WBX4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1246995:AFR_RS14365 ^@ http://purl.uniprot.org/uniprot/U5VWH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS38455 ^@ http://purl.uniprot.org/uniprot/U5WA54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS41230 ^@ http://purl.uniprot.org/uniprot/U5WEI9 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1246995:AFR_RS25725 ^@ http://purl.uniprot.org/uniprot/U5W5V6 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1246995:AFR_RS39025 ^@ http://purl.uniprot.org/uniprot/U5WA46 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1246995:AFR_RS32090 ^@ http://purl.uniprot.org/uniprot/U5W9K0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS43900 ^@ http://purl.uniprot.org/uniprot/U5W5M1 ^@ Similarity ^@ Belongs to the DyP-type peroxidase family. http://togogenome.org/gene/1246995:AFR_RS15615 ^@ http://purl.uniprot.org/uniprot/U5VWK4 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1246995:AFR_RS34275 ^@ http://purl.uniprot.org/uniprot/U5W7J1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS39405 ^@ http://purl.uniprot.org/uniprot/U5WDV7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1246995:AFR_RS00445 ^@ http://purl.uniprot.org/uniprot/U5VRL8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS26175 ^@ http://purl.uniprot.org/uniprot/U5W2W1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS10625 ^@ http://purl.uniprot.org/uniprot/U5VU45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS34945 ^@ http://purl.uniprot.org/uniprot/U5WB59 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 12 (cellulase H) family. http://togogenome.org/gene/1246995:AFR_RS32875 ^@ http://purl.uniprot.org/uniprot/U5W723 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1246995:AFR_RS03880 ^@ http://purl.uniprot.org/uniprot/U5VQK1 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS41775 ^@ http://purl.uniprot.org/uniprot/U5WC80 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PPase family.|||Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.|||Cytoplasm|||Homohexamer. http://togogenome.org/gene/1246995:AFR_RS09375 ^@ http://purl.uniprot.org/uniprot/U5VWX6 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1246995:AFR_RS46070 ^@ http://purl.uniprot.org/uniprot/U5VVR8 ^@ Similarity ^@ Belongs to the GMC oxidoreductase family. http://togogenome.org/gene/1246995:AFR_RS24750 ^@ http://purl.uniprot.org/uniprot/U5W2E6 ^@ Similarity ^@ Belongs to the tannase family. http://togogenome.org/gene/1246995:AFR_RS04975 ^@ http://purl.uniprot.org/uniprot/U5VQN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1246995:AFR_RS37680 ^@ http://purl.uniprot.org/uniprot/U5W9Q4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1246995:AFR_RS02930 ^@ http://purl.uniprot.org/uniprot/U5VT10 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS22390 ^@ http://purl.uniprot.org/uniprot/U5W127 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS01625 ^@ http://purl.uniprot.org/uniprot/U5VP91 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnA subfamily.|||Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1246995:AFR_RS10405 ^@ http://purl.uniprot.org/uniprot/U5VX94 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1246995:AFR_RS31140 ^@ http://purl.uniprot.org/uniprot/U5W5H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS02255 ^@ http://purl.uniprot.org/uniprot/U5VPJ9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1246995:AFR_RS20965 ^@ http://purl.uniprot.org/uniprot/U5W3C0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1246995:AFR_RS00610 ^@ http://purl.uniprot.org/uniprot/U5VNN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS05165 ^@ http://purl.uniprot.org/uniprot/U5VUJ5 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1246995:AFR_RS11290 ^@ http://purl.uniprot.org/uniprot/U5VUM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS41455 ^@ http://purl.uniprot.org/uniprot/U5WBB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS10530 ^@ http://purl.uniprot.org/uniprot/U5VXB9 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. http://togogenome.org/gene/1246995:AFR_RS35875 ^@ http://purl.uniprot.org/uniprot/U5WBM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS09535 ^@ http://purl.uniprot.org/uniprot/U5VT75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS00160 ^@ http://purl.uniprot.org/uniprot/U5VRG6 ^@ Similarity ^@ Belongs to the heat shock protein 90 family. http://togogenome.org/gene/1246995:AFR_RS10585 ^@ http://purl.uniprot.org/uniprot/U5VXJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS36950 ^@ http://purl.uniprot.org/uniprot/U5W909 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS10680 ^@ http://purl.uniprot.org/uniprot/U5VXE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS09755 ^@ http://purl.uniprot.org/uniprot/U5VTA9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1246995:AFR_RS16430 ^@ http://purl.uniprot.org/uniprot/U5W0Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16505 ^@ http://purl.uniprot.org/uniprot/U5W102 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS43055 ^@ http://purl.uniprot.org/uniprot/U5WCD4 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS42605 ^@ http://purl.uniprot.org/uniprot/U5WFB6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EccB family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS04585 ^@ http://purl.uniprot.org/uniprot/U5VU07 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1246995:AFR_RS06735 ^@ http://purl.uniprot.org/uniprot/U5VRP5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS34310 ^@ http://purl.uniprot.org/uniprot/U5WAY3 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS38190 ^@ http://purl.uniprot.org/uniprot/U5W9G3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/1246995:AFR_RS10225 ^@ http://purl.uniprot.org/uniprot/U5VU25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS30005 ^@ http://purl.uniprot.org/uniprot/U5W5F3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reductive amination of pyruvate to L-alanine. http://togogenome.org/gene/1246995:AFR_RS26265 ^@ http://purl.uniprot.org/uniprot/U5W391 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS10735 ^@ http://purl.uniprot.org/uniprot/U5VXM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1246995:AFR_RS10120 ^@ http://purl.uniprot.org/uniprot/U5VU03 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS01680 ^@ http://purl.uniprot.org/uniprot/U5VSD1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1246995:AFR_RS09540 ^@ http://purl.uniprot.org/uniprot/U5VTJ3 ^@ Caution|||PTM|||Subcellular Location Annotation|||Subunit ^@ Binds 2 heme c groups covalently per subunit.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The cytochrome bc1 complex is composed of a cytochrome b (QcrB), the Rieske iron-sulfur protein (QcrA) and a diheme cytochrome c (QcrC) subunit. http://togogenome.org/gene/1246995:AFR_RS10105 ^@ http://purl.uniprot.org/uniprot/U5VTU2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS09675 ^@ http://purl.uniprot.org/uniprot/U5VTR9 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS00930 ^@ http://purl.uniprot.org/uniprot/U5VNU8 ^@ Similarity ^@ Belongs to the DNA photolyase family. http://togogenome.org/gene/1246995:AFR_RS37505 ^@ http://purl.uniprot.org/uniprot/U5W9L8 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1246995:AFR_RS24215 ^@ http://purl.uniprot.org/uniprot/U5W255 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/1246995:AFR_RS26615 ^@ http://purl.uniprot.org/uniprot/U5W2Y8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04915 ^@ http://purl.uniprot.org/uniprot/U5VUE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS24095 ^@ http://purl.uniprot.org/uniprot/U5W1I6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS34355 ^@ http://purl.uniprot.org/uniprot/U5WAU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS38860 ^@ http://purl.uniprot.org/uniprot/U5WDG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS03265 ^@ http://purl.uniprot.org/uniprot/U5VPP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS32560 ^@ http://purl.uniprot.org/uniprot/U5W9T6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS07155 ^@ http://purl.uniprot.org/uniprot/U5VRV5 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1246995:AFR_RS08190 ^@ http://purl.uniprot.org/uniprot/U5VSW4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1246995:AFR_RS40360 ^@ http://purl.uniprot.org/uniprot/U5WBC2 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1246995:AFR_RS10150 ^@ http://purl.uniprot.org/uniprot/U5VTI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DivIVA family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS11275 ^@ http://purl.uniprot.org/uniprot/U5VUH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurD2 subfamily.|||Cell wall formation. Catalyzes the addition of L-glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS27445 ^@ http://purl.uniprot.org/uniprot/U5W3X7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1246995:AFR_RS10670 ^@ http://purl.uniprot.org/uniprot/U5VTS5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS08860 ^@ http://purl.uniprot.org/uniprot/U5VSW5 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1246995:AFR_RS35330 ^@ http://purl.uniprot.org/uniprot/U5WBG3 ^@ Similarity ^@ Belongs to the WrbA family. http://togogenome.org/gene/1246995:AFR_RS21115 ^@ http://purl.uniprot.org/uniprot/U5W3E8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS25870 ^@ http://purl.uniprot.org/uniprot/U5W2E5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS06360 ^@ http://purl.uniprot.org/uniprot/U5VVA5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Cell membrane|||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.|||Membrane http://togogenome.org/gene/1246995:AFR_RS37530 ^@ http://purl.uniprot.org/uniprot/U5W9M2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1246995:AFR_RS36690 ^@ http://purl.uniprot.org/uniprot/U5W8W4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS12910 ^@ http://purl.uniprot.org/uniprot/U5VVE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS10875 ^@ http://purl.uniprot.org/uniprot/U5VU92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS15040 ^@ http://purl.uniprot.org/uniprot/U5VW98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS38780 ^@ http://purl.uniprot.org/uniprot/U5WD70 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS03065 ^@ http://purl.uniprot.org/uniprot/U5VTA4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. http://togogenome.org/gene/1246995:AFR_RS07015 ^@ http://purl.uniprot.org/uniprot/U5VS49 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 20 family. http://togogenome.org/gene/1246995:AFR_RS42020 ^@ http://purl.uniprot.org/uniprot/U5WFC9 ^@ Similarity ^@ Belongs to the DnaX/STICHEL family. http://togogenome.org/gene/1246995:AFR_RS10915 ^@ http://purl.uniprot.org/uniprot/U5VUF5 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS17900 ^@ http://purl.uniprot.org/uniprot/U5VXV8 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1246995:AFR_RS42650 ^@ http://purl.uniprot.org/uniprot/U5WC60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS22155 ^@ http://purl.uniprot.org/uniprot/U5W0M7 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/1246995:AFR_RS20685 ^@ http://purl.uniprot.org/uniprot/U5W305 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS34080 ^@ http://purl.uniprot.org/uniprot/U5W7F0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1246995:AFR_RS31625 ^@ http://purl.uniprot.org/uniprot/U5W6E4 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS04880 ^@ http://purl.uniprot.org/uniprot/U5VQY1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1246995:AFR_RS35640 ^@ http://purl.uniprot.org/uniprot/U5W803 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS20425 ^@ http://purl.uniprot.org/uniprot/U5VZA5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1246995:AFR_RS13350 ^@ http://purl.uniprot.org/uniprot/U5VVV0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS27075 ^@ http://purl.uniprot.org/uniprot/U5W6P6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS08300 ^@ http://purl.uniprot.org/uniprot/U5VST5 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS08105 ^@ http://purl.uniprot.org/uniprot/U5VSP6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS35685 ^@ http://purl.uniprot.org/uniprot/U5W8M1 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1246995:AFR_RS25575 ^@ http://purl.uniprot.org/uniprot/U5W5S8 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS25615 ^@ http://purl.uniprot.org/uniprot/U5W294 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37040 ^@ http://purl.uniprot.org/uniprot/U5WCA3 ^@ Similarity ^@ Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS40625 ^@ http://purl.uniprot.org/uniprot/U5WE83 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1246995:AFR_RS36695 ^@ http://purl.uniprot.org/uniprot/U5WC52 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS04460 ^@ http://purl.uniprot.org/uniprot/U5VTY2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1246995:AFR_RS12775 ^@ http://purl.uniprot.org/uniprot/U5VVI7 ^@ Function|||Similarity ^@ Belongs to the UPF0677 family.|||Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity. http://togogenome.org/gene/1246995:AFR_RS10115 ^@ http://purl.uniprot.org/uniprot/U5VXA5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS35775 ^@ http://purl.uniprot.org/uniprot/U5WBK1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS13510 ^@ http://purl.uniprot.org/uniprot/U5VZ14 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS31055 ^@ http://purl.uniprot.org/uniprot/U5W927 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the urease gamma subunit family.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1246995:AFR_RS20405 ^@ http://purl.uniprot.org/uniprot/U5VZK1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS16225 ^@ http://purl.uniprot.org/uniprot/U5VXA6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1246995:AFR_RS01365 ^@ http://purl.uniprot.org/uniprot/U5VP33 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS02445 ^@ http://purl.uniprot.org/uniprot/U5VPM8 ^@ Similarity ^@ Belongs to the cysteine dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS42360 ^@ http://purl.uniprot.org/uniprot/U5WBW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS35800 ^@ http://purl.uniprot.org/uniprot/U5WBK6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS05345 ^@ http://purl.uniprot.org/uniprot/U5VRA9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1246995:AFR_RS19135 ^@ http://purl.uniprot.org/uniprot/U5W279 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS41340 ^@ http://purl.uniprot.org/uniprot/U5WEV5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS14445 ^@ http://purl.uniprot.org/uniprot/U5VW07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS38070 ^@ http://purl.uniprot.org/uniprot/U5W9K3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS41580 ^@ http://purl.uniprot.org/uniprot/U5WBE5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS35310 ^@ http://purl.uniprot.org/uniprot/U5W8E9 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1246995:AFR_RS13575 ^@ http://purl.uniprot.org/uniprot/U5VVF2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS03395 ^@ http://purl.uniprot.org/uniprot/U5VQ69 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS17120 ^@ http://purl.uniprot.org/uniprot/U5W143 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1246995:AFR_RS10305 ^@ http://purl.uniprot.org/uniprot/U5VTY0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS23555 ^@ http://purl.uniprot.org/uniprot/U5W4M5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/1246995:AFR_RS16860 ^@ http://purl.uniprot.org/uniprot/U5VXD7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS06730 ^@ http://purl.uniprot.org/uniprot/U5VS43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS37740 ^@ http://purl.uniprot.org/uniprot/U5W984 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS10135 ^@ http://purl.uniprot.org/uniprot/U5VX42 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1246995:AFR_RS37615 ^@ http://purl.uniprot.org/uniprot/U5W9C0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS05090 ^@ http://purl.uniprot.org/uniprot/U5VUI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS35440 ^@ http://purl.uniprot.org/uniprot/U5W7W7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS11040 ^@ http://purl.uniprot.org/uniprot/U5VUI1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS26225 ^@ http://purl.uniprot.org/uniprot/U5W648 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1246995:AFR_RS05050 ^@ http://purl.uniprot.org/uniprot/U5VQP9 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1246995:AFR_RS10130 ^@ http://purl.uniprot.org/uniprot/U5VTU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1246995:AFR_RS23875 ^@ http://purl.uniprot.org/uniprot/U5W1I8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS25535 ^@ http://purl.uniprot.org/uniprot/U5W2V0 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1246995:AFR_RS06745 ^@ http://purl.uniprot.org/uniprot/U5VV91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.|||Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.|||The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD). http://togogenome.org/gene/1246995:AFR_RS33680 ^@ http://purl.uniprot.org/uniprot/U5W749 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS28195 ^@ http://purl.uniprot.org/uniprot/U5W7A4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/1246995:AFR_RS41905 ^@ http://purl.uniprot.org/uniprot/U5WBN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS17920 ^@ http://purl.uniprot.org/uniprot/U5VYH5 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS13585 ^@ http://purl.uniprot.org/uniprot/U5VZ30 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS22715 ^@ http://purl.uniprot.org/uniprot/U5W192 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS35005 ^@ http://purl.uniprot.org/uniprot/U5W887 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LamB/PxpA family.|||Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.|||Forms a complex composed of PxpA, PxpB and PxpC. http://togogenome.org/gene/1246995:AFR_RS13460 ^@ http://purl.uniprot.org/uniprot/U5VVQ6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS39430 ^@ http://purl.uniprot.org/uniprot/U5WDW0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS09665 ^@ http://purl.uniprot.org/uniprot/U5VWW1 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS36725 ^@ http://purl.uniprot.org/uniprot/U5WCC4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1246995:AFR_RS03305 ^@ http://purl.uniprot.org/uniprot/U5VTF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37555 ^@ http://purl.uniprot.org/uniprot/U5W9M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1246995:AFR_RS32410 ^@ http://purl.uniprot.org/uniprot/U5W9W6 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1246995:AFR_RS46080 ^@ http://purl.uniprot.org/uniprot/U5VWE1 ^@ Similarity ^@ Belongs to the ros/MucR family. http://togogenome.org/gene/1246995:AFR_RS02285 ^@ http://purl.uniprot.org/uniprot/U5VSP4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS30760 ^@ http://purl.uniprot.org/uniprot/U5W5U4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1246995:AFR_RS24985 ^@ http://purl.uniprot.org/uniprot/U5W278 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1246995:AFR_RS23695 ^@ http://purl.uniprot.org/uniprot/U5W145 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS37635 ^@ http://purl.uniprot.org/uniprot/U5W966 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the NOS family. Bacterial NOS oxygenase subfamily.|||Catalyzes the production of nitric oxide.|||Homodimer.|||This protein is similar to the oxygenase domain of eukaryotic nitric oxide synthases but lacks the reductase domain which, in eukaryotes, is responsible for transfer of electrons to the ferric heme during nitric oxide synthesis. http://togogenome.org/gene/1246995:AFR_RS07935 ^@ http://purl.uniprot.org/uniprot/U5VVV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1246995:AFR_RS04840 ^@ http://purl.uniprot.org/uniprot/U5VUD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1246995:AFR_RS14815 ^@ http://purl.uniprot.org/uniprot/U5VWQ7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS02370 ^@ http://purl.uniprot.org/uniprot/U5VPL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS05620 ^@ http://purl.uniprot.org/uniprot/U5VUJ7 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1246995:AFR_RS37160 ^@ http://purl.uniprot.org/uniprot/U5W8Y5 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1246995:AFR_RS17785 ^@ http://purl.uniprot.org/uniprot/U5VYF0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 10 (cellulase F) family. http://togogenome.org/gene/1246995:AFR_RS00755 ^@ http://purl.uniprot.org/uniprot/U5VNQ9 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1246995:AFR_RS37450 ^@ http://purl.uniprot.org/uniprot/U5WCQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS38450 ^@ http://purl.uniprot.org/uniprot/U5WD78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30735 ^@ http://purl.uniprot.org/uniprot/U5W5U0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS31905 ^@ http://purl.uniprot.org/uniprot/U5W610 ^@ Similarity ^@ Belongs to the peptidase S15 family. http://togogenome.org/gene/1246995:AFR_RS02040 ^@ http://purl.uniprot.org/uniprot/U5VSS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS20325 ^@ http://purl.uniprot.org/uniprot/U5VZ88 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS31725 ^@ http://purl.uniprot.org/uniprot/U5W6F8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyl hydrolase 13 family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS10220 ^@ http://purl.uniprot.org/uniprot/U5VXC6 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS09820 ^@ http://purl.uniprot.org/uniprot/U5VX50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS38255 ^@ http://purl.uniprot.org/uniprot/U5WD42 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1246995:AFR_RS40310 ^@ http://purl.uniprot.org/uniprot/U5WAN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1246995:AFR_RS36650 ^@ http://purl.uniprot.org/uniprot/U5WCA6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS05560 ^@ http://purl.uniprot.org/uniprot/U5VQY7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1246995:AFR_RS15965 ^@ http://purl.uniprot.org/uniprot/U5VWT0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS43080 ^@ http://purl.uniprot.org/uniprot/U5WFK9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS05595 ^@ http://purl.uniprot.org/uniprot/U5VUJ3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics.|||Belongs to the MshB deacetylase family. Mca subfamily.|||Binds 1 zinc ion per subunit.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS14775 ^@ http://purl.uniprot.org/uniprot/U5VWH7 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS40140 ^@ http://purl.uniprot.org/uniprot/U5WB77 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1246995:AFR_RS31735 ^@ http://purl.uniprot.org/uniprot/U5W636 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS16655 ^@ http://purl.uniprot.org/uniprot/U5VXL9 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS35815 ^@ http://purl.uniprot.org/uniprot/U5W839 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1246995:AFR_RS05475 ^@ http://purl.uniprot.org/uniprot/U5VUP6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1246995:AFR_RS30860 ^@ http://purl.uniprot.org/uniprot/U5W5W5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS19455 ^@ http://purl.uniprot.org/uniprot/U5VYU3 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS17755 ^@ http://purl.uniprot.org/uniprot/U5W1L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS43140 ^@ http://purl.uniprot.org/uniprot/U5WFW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04715 ^@ http://purl.uniprot.org/uniprot/U5VUA9 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1246995:AFR_RS04665 ^@ http://purl.uniprot.org/uniprot/U5VUA1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS04700 ^@ http://purl.uniprot.org/uniprot/U5VQI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1246995:AFR_RS13595 ^@ http://purl.uniprot.org/uniprot/U5VW04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS42325 ^@ http://purl.uniprot.org/uniprot/U5WFI2 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1246995:AFR_RS03050 ^@ http://purl.uniprot.org/uniprot/U5VPJ4 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS19885 ^@ http://purl.uniprot.org/uniprot/U5W2K9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1246995:AFR_RS20815 ^@ http://purl.uniprot.org/uniprot/U5W390 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS40630 ^@ http://purl.uniprot.org/uniprot/U5WEG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1246995:AFR_RS09835 ^@ http://purl.uniprot.org/uniprot/U5VTP2 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1246995:AFR_RS34880 ^@ http://purl.uniprot.org/uniprot/U5W861 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS09230 ^@ http://purl.uniprot.org/uniprot/U5VTJ9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the glutamine synthetase family.|||Cytoplasm|||Oligomer of 12 subunits arranged in the form of two hexagons. http://togogenome.org/gene/1246995:AFR_RS01020 ^@ http://purl.uniprot.org/uniprot/U5VNW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05790 ^@ http://purl.uniprot.org/uniprot/U5VRE8 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1246995:AFR_RS10215 ^@ http://purl.uniprot.org/uniprot/U5VX55 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1246995:AFR_RS31245 ^@ http://purl.uniprot.org/uniprot/U5VXL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1246995:AFR_RS32220 ^@ http://purl.uniprot.org/uniprot/U5W6B6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS36140 ^@ http://purl.uniprot.org/uniprot/U5W8B0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1246995:AFR_RS00040 ^@ http://purl.uniprot.org/uniprot/U5VNB8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1246995:AFR_RS08695 ^@ http://purl.uniprot.org/uniprot/U5VW96 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS22020 ^@ http://purl.uniprot.org/uniprot/U5W0V6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS30700 ^@ http://purl.uniprot.org/uniprot/U5W8Q2 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1246995:AFR_RS33395 ^@ http://purl.uniprot.org/uniprot/U5W7C1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS41950 ^@ http://purl.uniprot.org/uniprot/U5WCA9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS36755 ^@ http://purl.uniprot.org/uniprot/U5W991 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/1246995:AFR_RS25545 ^@ http://purl.uniprot.org/uniprot/U5W2I5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS04240 ^@ http://purl.uniprot.org/uniprot/U5VQM8 ^@ Similarity ^@ Belongs to the ComB family. http://togogenome.org/gene/1246995:AFR_RS40620 ^@ http://purl.uniprot.org/uniprot/U5WB14 ^@ Similarity ^@ Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1246995:AFR_RS05020 ^@ http://purl.uniprot.org/uniprot/U5VR45 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1246995:AFR_RS01395 ^@ http://purl.uniprot.org/uniprot/U5VNQ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04620 ^@ http://purl.uniprot.org/uniprot/U5VQW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1246995:AFR_RS10465 ^@ http://purl.uniprot.org/uniprot/U5VU73 ^@ Similarity|||Subunit ^@ Belongs to the pyruvate kinase family.|||Homotetramer. http://togogenome.org/gene/1246995:AFR_RS40950 ^@ http://purl.uniprot.org/uniprot/U5WB80 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the acetyltransferase family. MshD subfamily.|||Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS01735 ^@ http://purl.uniprot.org/uniprot/U5VSM0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the complex I 75 kDa subunit family.|||Binds 1 [2Fe-2S] cluster per subunit.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS00200 ^@ http://purl.uniprot.org/uniprot/U5VMX4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS19945 ^@ http://purl.uniprot.org/uniprot/U5VZM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS42045 ^@ http://purl.uniprot.org/uniprot/U5WF21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18875 ^@ http://purl.uniprot.org/uniprot/U5VZ16 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS10340 ^@ http://purl.uniprot.org/uniprot/U5VXE9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS06750 ^@ http://purl.uniprot.org/uniprot/U5VVH2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS11160 ^@ http://purl.uniprot.org/uniprot/U5VXV3 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/1246995:AFR_RS04650 ^@ http://purl.uniprot.org/uniprot/U5VQI2 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS24610 ^@ http://purl.uniprot.org/uniprot/U5W219 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Catalyzes the reversible hydration of carbon dioxide to form bicarbonate. http://togogenome.org/gene/1246995:AFR_RS36475 ^@ http://purl.uniprot.org/uniprot/U5WC29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS30625 ^@ http://purl.uniprot.org/uniprot/U5W8N9 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1246995:AFR_RS15285 ^@ http://purl.uniprot.org/uniprot/U5VX04 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS20755 ^@ http://purl.uniprot.org/uniprot/U5VZS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS11795 ^@ http://purl.uniprot.org/uniprot/U5VUJ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04550 ^@ http://purl.uniprot.org/uniprot/U5VQG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1246995:AFR_RS32660 ^@ http://purl.uniprot.org/uniprot/U5W9V5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS26905 ^@ http://purl.uniprot.org/uniprot/U5W3M7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1246995:AFR_RS33640 ^@ http://purl.uniprot.org/uniprot/U5WAI3 ^@ Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. http://togogenome.org/gene/1246995:AFR_RS38730 ^@ http://purl.uniprot.org/uniprot/U5WD60 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the type 2 tetrahydrodipicolinate N-succinyltransferase family.|||Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.|||Cytoplasm|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS36470 ^@ http://purl.uniprot.org/uniprot/U5WBZ2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1246995:AFR_RS13095 ^@ http://purl.uniprot.org/uniprot/U5VYY4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04570 ^@ http://purl.uniprot.org/uniprot/U5VQV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1246995:AFR_RS24815 ^@ http://purl.uniprot.org/uniprot/U5W5E2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12650 ^@ http://purl.uniprot.org/uniprot/U5VVG3 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1246995:AFR_RS13770 ^@ http://purl.uniprot.org/uniprot/U5VW37 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09715 ^@ http://purl.uniprot.org/uniprot/U5VWX0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS21365 ^@ http://purl.uniprot.org/uniprot/U5W3J3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1246995:AFR_RS32425 ^@ http://purl.uniprot.org/uniprot/U5W6E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1246995:AFR_RS16800 ^@ http://purl.uniprot.org/uniprot/U5W144 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1246995:AFR_RS09760 ^@ http://purl.uniprot.org/uniprot/U5VTN0 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1246995:AFR_RS39455 ^@ http://purl.uniprot.org/uniprot/U5WDW5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS00695 ^@ http://purl.uniprot.org/uniprot/U5VRR5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1246995:AFR_RS06965 ^@ http://purl.uniprot.org/uniprot/U5VS40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS29575 ^@ http://purl.uniprot.org/uniprot/U5W563 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/1246995:AFR_RS35350 ^@ http://purl.uniprot.org/uniprot/U5WBD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III. http://togogenome.org/gene/1246995:AFR_RS23015 ^@ http://purl.uniprot.org/uniprot/U5W1E6 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1246995:AFR_RS18205 ^@ http://purl.uniprot.org/uniprot/U5W1N2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1246995:AFR_RS14065 ^@ http://purl.uniprot.org/uniprot/U5VZF4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS16470 ^@ http://purl.uniprot.org/uniprot/U5VXI7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS13145 ^@ http://purl.uniprot.org/uniprot/U5VYZ4 ^@ Similarity ^@ Belongs to the extradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1246995:AFR_RS13005 ^@ http://purl.uniprot.org/uniprot/U5VV37 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS27525 ^@ http://purl.uniprot.org/uniprot/U5W3F8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1246995:AFR_RS21440 ^@ http://purl.uniprot.org/uniprot/U5W3K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS14520 ^@ http://purl.uniprot.org/uniprot/U5VW16 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1246995:AFR_RS39815 ^@ http://purl.uniprot.org/uniprot/U5WDT0 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS39410 ^@ http://purl.uniprot.org/uniprot/U5WAS7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1246995:AFR_RS10495 ^@ http://purl.uniprot.org/uniprot/U5VTP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04245 ^@ http://purl.uniprot.org/uniprot/U5VTU9 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1246995:AFR_RS02630 ^@ http://purl.uniprot.org/uniprot/U5VSV4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS40995 ^@ http://purl.uniprot.org/uniprot/U5WB20 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16355 ^@ http://purl.uniprot.org/uniprot/U5W0T7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An FAD-requiring monooxygenase active on some tetracycline antibiotic derivatives, which leads to their inactivation. Hydroxylates carbon 11a of tetracycline and some analogs.|||Belongs to the aromatic-ring hydroxylase family. TetX subfamily.|||Consists of an N-terminal FAD-binding domain with a Rossman fold and a C-terminal substrate-binding domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS03355 ^@ http://purl.uniprot.org/uniprot/U5VTG1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS02165 ^@ http://purl.uniprot.org/uniprot/U5VSU3 ^@ Function|||Similarity ^@ Belongs to the PNP/UDP phosphorylase family. Futalosine hydrolase subfamily.|||Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1246995:AFR_RS30205 ^@ http://purl.uniprot.org/uniprot/U5W8L4 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/1246995:AFR_RS19630 ^@ http://purl.uniprot.org/uniprot/U5VYW9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||In the N-terminal section; belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1246995:AFR_RS36520 ^@ http://purl.uniprot.org/uniprot/U5WC04 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS26720 ^@ http://purl.uniprot.org/uniprot/U5W6I5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS10635 ^@ http://purl.uniprot.org/uniprot/U5VXK3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1246995:AFR_RS02925 ^@ http://purl.uniprot.org/uniprot/U5VPY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS04310 ^@ http://purl.uniprot.org/uniprot/U5VQD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS18670 ^@ http://purl.uniprot.org/uniprot/U5VYB3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS37640 ^@ http://purl.uniprot.org/uniprot/U5W9C5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS30615 ^@ http://purl.uniprot.org/uniprot/U5W555 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS34930 ^@ http://purl.uniprot.org/uniprot/U5W873 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS25315 ^@ http://purl.uniprot.org/uniprot/U5W5N5 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1246995:AFR_RS09470 ^@ http://purl.uniprot.org/uniprot/U5VTI1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS20570 ^@ http://purl.uniprot.org/uniprot/U5W000 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1246995:AFR_RS01930 ^@ http://purl.uniprot.org/uniprot/U5VSH8 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS14120 ^@ http://purl.uniprot.org/uniprot/U5VZM3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS19105 ^@ http://purl.uniprot.org/uniprot/U5VYY7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS43150 ^@ http://purl.uniprot.org/uniprot/U5WC87 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS33630 ^@ http://purl.uniprot.org/uniprot/U5W736 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1246995:AFR_RS40585 ^@ http://purl.uniprot.org/uniprot/U5WBG5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1246995:AFR_RS26425 ^@ http://purl.uniprot.org/uniprot/U5W696 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS07465 ^@ http://purl.uniprot.org/uniprot/U5VVM5 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1246995:AFR_RS15260 ^@ http://purl.uniprot.org/uniprot/U5VX00 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/1246995:AFR_RS32405 ^@ http://purl.uniprot.org/uniprot/U5W9Q6 ^@ Similarity ^@ Belongs to the F420H(2)-dependent quinone reductase family. http://togogenome.org/gene/1246995:AFR_RS34550 ^@ http://purl.uniprot.org/uniprot/U5W7N8 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1246995:AFR_RS08170 ^@ http://purl.uniprot.org/uniprot/U5VSC9 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1246995:AFR_RS42315 ^@ http://purl.uniprot.org/uniprot/U5WC19 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS31480 ^@ http://purl.uniprot.org/uniprot/U5W5Q1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18775 ^@ http://purl.uniprot.org/uniprot/U5VYN5 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1246995:AFR_RS05095 ^@ http://purl.uniprot.org/uniprot/U5VR59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS19695 ^@ http://purl.uniprot.org/uniprot/U5W2P0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1246995:AFR_RS47785 ^@ http://purl.uniprot.org/uniprot/U5VV25 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1246995:AFR_RS08910 ^@ http://purl.uniprot.org/uniprot/U5VTF2 ^@ Similarity ^@ Belongs to the barstar family. http://togogenome.org/gene/1246995:AFR_RS33500 ^@ http://purl.uniprot.org/uniprot/U5W6U7 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1246995:AFR_RS40280 ^@ http://purl.uniprot.org/uniprot/U5WBA8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1246995:AFR_RS37240 ^@ http://purl.uniprot.org/uniprot/U5W957 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1246995:AFR_RS14880 ^@ http://purl.uniprot.org/uniprot/U5VZU4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS22690 ^@ http://purl.uniprot.org/uniprot/U5W187 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS01450 ^@ http://purl.uniprot.org/uniprot/U5VP58 ^@ Similarity ^@ Belongs to the UbiD family. http://togogenome.org/gene/1246995:AFR_RS04670 ^@ http://purl.uniprot.org/uniprot/U5VQX9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1246995:AFR_RS34135 ^@ http://purl.uniprot.org/uniprot/U5WAR7 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1246995:AFR_RS37675 ^@ http://purl.uniprot.org/uniprot/U5WCU6 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09900 ^@ http://purl.uniprot.org/uniprot/U5VTW0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1246995:AFR_RS29230 ^@ http://purl.uniprot.org/uniprot/U5W4G6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS35500 ^@ http://purl.uniprot.org/uniprot/U5WBG1 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1246995:AFR_RS02345 ^@ http://purl.uniprot.org/uniprot/U5VPK8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS06380 ^@ http://purl.uniprot.org/uniprot/U5VV26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30440 ^@ http://purl.uniprot.org/uniprot/U5W523 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1246995:AFR_RS03010 ^@ http://purl.uniprot.org/uniprot/U5VT26 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS44135 ^@ http://purl.uniprot.org/uniprot/U5W5L3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS19480 ^@ http://purl.uniprot.org/uniprot/U5VYU8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS19110 ^@ http://purl.uniprot.org/uniprot/U5W276 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS28130 ^@ http://purl.uniprot.org/uniprot/U5W4B6 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1246995:AFR_RS04605 ^@ http://purl.uniprot.org/uniprot/U5VQT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS40095 ^@ http://purl.uniprot.org/uniprot/U5WAK9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1246995:AFR_RS43400 ^@ http://purl.uniprot.org/uniprot/U5VRR1 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1246995:AFR_RS40020 ^@ http://purl.uniprot.org/uniprot/U5WAQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS39005 ^@ http://purl.uniprot.org/uniprot/U5WDB7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1246995:AFR_RS22805 ^@ http://purl.uniprot.org/uniprot/U5W492 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/1246995:AFR_RS37480 ^@ http://purl.uniprot.org/uniprot/U5W9L3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS10945 ^@ http://purl.uniprot.org/uniprot/U5VTY1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1246995:AFR_RS27295 ^@ http://purl.uniprot.org/uniprot/U5W6T9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS23720 ^@ http://purl.uniprot.org/uniprot/U5W150 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1246995:AFR_RS22960 ^@ http://purl.uniprot.org/uniprot/U5W4H9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07965 ^@ http://purl.uniprot.org/uniprot/U5VW26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1246995:AFR_RS09080 ^@ http://purl.uniprot.org/uniprot/U5VWS6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS10250 ^@ http://purl.uniprot.org/uniprot/U5VTJ5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS05525 ^@ http://purl.uniprot.org/uniprot/U5VUQ5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1246995:AFR_RS10140 ^@ http://purl.uniprot.org/uniprot/U5VXB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1246995:AFR_RS05005 ^@ http://purl.uniprot.org/uniprot/U5VR04 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1246995:AFR_RS40375 ^@ http://purl.uniprot.org/uniprot/U5WE37 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1246995:AFR_RS04295 ^@ http://purl.uniprot.org/uniprot/U5VTV7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS37100 ^@ http://purl.uniprot.org/uniprot/U5W9E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS37165 ^@ http://purl.uniprot.org/uniprot/U5W945 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1246995:AFR_RS07390 ^@ http://purl.uniprot.org/uniprot/U5VSB3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS08725 ^@ http://purl.uniprot.org/uniprot/U5VWH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04660 ^@ http://purl.uniprot.org/uniprot/U5VU23 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1246995:AFR_RS00345 ^@ http://purl.uniprot.org/uniprot/U5VRR8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04920 ^@ http://purl.uniprot.org/uniprot/U5VR25 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1246995:AFR_RS06105 ^@ http://purl.uniprot.org/uniprot/U5VUT1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS38325 ^@ http://purl.uniprot.org/uniprot/U5WD54 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1246995:AFR_RS12130 ^@ http://purl.uniprot.org/uniprot/U5VUN8 ^@ Subcellular Location Annotation ^@ Endosome membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS07730 ^@ http://purl.uniprot.org/uniprot/U5VSH2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1246995:AFR_RS16150 ^@ http://purl.uniprot.org/uniprot/U5VX90 ^@ Function|||Similarity ^@ Belongs to the bacterial two-domain DSD family.|||Catalyzes the conversion of 3-dehydroshikimate to protocatechuate (3,4-dihydroxybenzoate), a common intermediate of quinate and shikimate degradation pathways. http://togogenome.org/gene/1246995:AFR_RS02260 ^@ http://purl.uniprot.org/uniprot/U5VSN9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS41675 ^@ http://purl.uniprot.org/uniprot/U5WC63 ^@ Function|||Similarity ^@ Belongs to the DHNA family.|||Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin. http://togogenome.org/gene/1246995:AFR_RS26480 ^@ http://purl.uniprot.org/uniprot/U5W6E8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1246995:AFR_RS17760 ^@ http://purl.uniprot.org/uniprot/U5VYE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS38815 ^@ http://purl.uniprot.org/uniprot/U5WAC2 ^@ Function|||Similarity ^@ Belongs to the EgtB family.|||Catalyzes the oxidative sulfurization of hercynine (N-alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/1246995:AFR_RS04565 ^@ http://purl.uniprot.org/uniprot/U5VU84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS40965 ^@ http://purl.uniprot.org/uniprot/U5WBN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PstS family.|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1246995:AFR_RS27760 ^@ http://purl.uniprot.org/uniprot/U5W727 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS20670 ^@ http://purl.uniprot.org/uniprot/U5W016 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS14695 ^@ http://purl.uniprot.org/uniprot/U5VW42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS37070 ^@ http://purl.uniprot.org/uniprot/U5WCI5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS20075 ^@ http://purl.uniprot.org/uniprot/U5VZ46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS01090 ^@ http://purl.uniprot.org/uniprot/U5VNX1 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS43165 ^@ http://purl.uniprot.org/uniprot/U5WFW8 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1246995:AFR_RS23610 ^@ http://purl.uniprot.org/uniprot/U5W4U8 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS34585 ^@ http://purl.uniprot.org/uniprot/U5WB31 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1246995:AFR_RS13615 ^@ http://purl.uniprot.org/uniprot/U5VZ78 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS09545 ^@ http://purl.uniprot.org/uniprot/U5VWT9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Rieske iron-sulfur protein family.|||Cell membrane|||Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis.|||Membrane http://togogenome.org/gene/1246995:AFR_RS24765 ^@ http://purl.uniprot.org/uniprot/U5W5D3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS05920 ^@ http://purl.uniprot.org/uniprot/U5VRG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1246995:AFR_RS30560 ^@ http://purl.uniprot.org/uniprot/U5W5R0 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1246995:AFR_RS40580 ^@ http://purl.uniprot.org/uniprot/U5WEG3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1246995:AFR_RS34820 ^@ http://purl.uniprot.org/uniprot/U5WB72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS04900 ^@ http://purl.uniprot.org/uniprot/U5VQM2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD. http://togogenome.org/gene/1246995:AFR_RS11345 ^@ http://purl.uniprot.org/uniprot/U5VU91 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS08440 ^@ http://purl.uniprot.org/uniprot/U5VSW2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS03380 ^@ http://purl.uniprot.org/uniprot/U5VTG8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1246995:AFR_RS40900 ^@ http://purl.uniprot.org/uniprot/U5WB70 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity ^@ Belongs to the nitrobindin family.|||Binds 1 heme b group per subunit, that coordinates a highly solvent-exposed Fe(III) atom.|||Forms a 10-stranded antiparallel beta-barrel structure able to accommodate a hydrophobic ligand in its interior. In fact, this fold hosts the heme group, which is located in a wide surface cleft.|||Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS05180 ^@ http://purl.uniprot.org/uniprot/U5VR38 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/1246995:AFR_RS22225 ^@ http://purl.uniprot.org/uniprot/U5W0N6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS30950 ^@ http://purl.uniprot.org/uniprot/U5W8U7 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1246995:AFR_RS31030 ^@ http://purl.uniprot.org/uniprot/U5W921 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1246995:AFR_RS32840 ^@ http://purl.uniprot.org/uniprot/U5W9Y9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS39645 ^@ http://purl.uniprot.org/uniprot/U5WE00 ^@ Subunit ^@ Heterodimer of an alpha and a beta chain. http://togogenome.org/gene/1246995:AFR_RS14990 ^@ http://purl.uniprot.org/uniprot/U5VW90 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1246995:AFR_RS03245 ^@ http://purl.uniprot.org/uniprot/U5VQ41 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1246995:AFR_RS07330 ^@ http://purl.uniprot.org/uniprot/U5VSE6 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS19910 ^@ http://purl.uniprot.org/uniprot/U5W2L4 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/1246995:AFR_RS36090 ^@ http://purl.uniprot.org/uniprot/U5W8A0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1246995:AFR_RS25005 ^@ http://purl.uniprot.org/uniprot/U5W1Y6 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1246995:AFR_RS13905 ^@ http://purl.uniprot.org/uniprot/U5VVR4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1246995:AFR_RS06065 ^@ http://purl.uniprot.org/uniprot/U5VRP4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1246995:AFR_RS15860 ^@ http://purl.uniprot.org/uniprot/U5VXB8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS01720 ^@ http://purl.uniprot.org/uniprot/U5VNV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS24450 ^@ http://purl.uniprot.org/uniprot/U5W1P2 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/1246995:AFR_RS23835 ^@ http://purl.uniprot.org/uniprot/U5W4S9 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS31020 ^@ http://purl.uniprot.org/uniprot/U5W5L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS04625 ^@ http://purl.uniprot.org/uniprot/U5VQH8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1246995:AFR_RS39895 ^@ http://purl.uniprot.org/uniprot/U5WE46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1246995:AFR_RS02300 ^@ http://purl.uniprot.org/uniprot/U5VP47 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1246995:AFR_RS00700 ^@ http://purl.uniprot.org/uniprot/U5VRX7 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1246995:AFR_RS00780 ^@ http://purl.uniprot.org/uniprot/U5VNR5 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1246995:AFR_RS13920 ^@ http://purl.uniprot.org/uniprot/U5VZI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12110 ^@ http://purl.uniprot.org/uniprot/U5VV03 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS15175 ^@ http://purl.uniprot.org/uniprot/U5VZZ7 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS31360 ^@ http://purl.uniprot.org/uniprot/U5W5M2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS15385 ^@ http://purl.uniprot.org/uniprot/U5VX25 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS40615 ^@ http://purl.uniprot.org/uniprot/U5WAT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1246995:AFR_RS33325 ^@ http://purl.uniprot.org/uniprot/U5W6X1 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1246995:AFR_RS22400 ^@ http://purl.uniprot.org/uniprot/U5W0R4 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/1246995:AFR_RS20290 ^@ http://purl.uniprot.org/uniprot/U5W2Z4 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. Lipase family. http://togogenome.org/gene/1246995:AFR_RS22460 ^@ http://purl.uniprot.org/uniprot/U5W491 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein SsuA/TauA family.|||Periplasm http://togogenome.org/gene/1246995:AFR_RS36095 ^@ http://purl.uniprot.org/uniprot/U5W8G9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1246995:AFR_RS32165 ^@ http://purl.uniprot.org/uniprot/U5W9L5 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrA/ParC subunit family. http://togogenome.org/gene/1246995:AFR_RS39940 ^@ http://purl.uniprot.org/uniprot/U5WAP0 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS15350 ^@ http://purl.uniprot.org/uniprot/U5W029 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1246995:AFR_RS39735 ^@ http://purl.uniprot.org/uniprot/U5WAL4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS20675 ^@ http://purl.uniprot.org/uniprot/U5VZE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS03490 ^@ http://purl.uniprot.org/uniprot/U5VPU2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS23980 ^@ http://purl.uniprot.org/uniprot/U5W4X4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS34860 ^@ http://purl.uniprot.org/uniprot/U5W7M5 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1246995:AFR_RS05195 ^@ http://purl.uniprot.org/uniprot/U5VR80 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1246995:AFR_RS04710 ^@ http://purl.uniprot.org/uniprot/U5VU32 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1246995:AFR_RS04990 ^@ http://purl.uniprot.org/uniprot/U5VUG2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1246995:AFR_RS37210 ^@ http://purl.uniprot.org/uniprot/U5W8Z5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1246995:AFR_RS26090 ^@ http://purl.uniprot.org/uniprot/U5W357 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1246995:AFR_RS07320 ^@ http://purl.uniprot.org/uniprot/U5VVK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS17280 ^@ http://purl.uniprot.org/uniprot/U5VY48 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS29385 ^@ http://purl.uniprot.org/uniprot/U5W4S0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS35835 ^@ http://purl.uniprot.org/uniprot/U5W8P7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS30280 ^@ http://purl.uniprot.org/uniprot/U5W8M5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS04490 ^@ http://purl.uniprot.org/uniprot/U5VTY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1246995:AFR_RS39070 ^@ http://purl.uniprot.org/uniprot/U5WA00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS34955 ^@ http://purl.uniprot.org/uniprot/U5W878 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS10070 ^@ http://purl.uniprot.org/uniprot/U5VTZ4 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1246995:AFR_RS26345 ^@ http://purl.uniprot.org/uniprot/U5W2Z7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS36500 ^@ http://purl.uniprot.org/uniprot/U5WC32 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ A probable RNA-binding protein.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS39180 ^@ http://purl.uniprot.org/uniprot/U5WDI9 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1246995:AFR_RS27425 ^@ http://purl.uniprot.org/uniprot/U5W3E1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37245 ^@ http://purl.uniprot.org/uniprot/U5WCE1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1246995:AFR_RS37855 ^@ http://purl.uniprot.org/uniprot/U5WCX4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS26760 ^@ http://purl.uniprot.org/uniprot/U5W316 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent condensation of GlcN-Ins and L-cysteine to form L-Cys-GlcN-Ins.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS25170 ^@ http://purl.uniprot.org/uniprot/U5W5R5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS14440 ^@ http://purl.uniprot.org/uniprot/U5VWJ3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 1 family. http://togogenome.org/gene/1246995:AFR_RS37020 ^@ http://purl.uniprot.org/uniprot/U5W8V9 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1246995:AFR_RS38540 ^@ http://purl.uniprot.org/uniprot/U5W9N9 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1246995:AFR_RS35890 ^@ http://purl.uniprot.org/uniprot/U5W854 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS17375 ^@ http://purl.uniprot.org/uniprot/U5W1E3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1246995:AFR_RS07175 ^@ http://purl.uniprot.org/uniprot/U5VSC0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS41295 ^@ http://purl.uniprot.org/uniprot/U5WBU8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1246995:AFR_RS35895 ^@ http://purl.uniprot.org/uniprot/U5W8C9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS03105 ^@ http://purl.uniprot.org/uniprot/U5VT47 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS34070 ^@ http://purl.uniprot.org/uniprot/U5W7S6 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1246995:AFR_RS05635 ^@ http://purl.uniprot.org/uniprot/U5VR02 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS36860 ^@ http://purl.uniprot.org/uniprot/U5W8T7 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1246995:AFR_RS43050 ^@ http://purl.uniprot.org/uniprot/U5WC70 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1246995:AFR_RS33335 ^@ http://purl.uniprot.org/uniprot/U5WAC5 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1246995:AFR_RS13330 ^@ http://purl.uniprot.org/uniprot/U5VV98 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS34605 ^@ http://purl.uniprot.org/uniprot/U5WAZ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS03590 ^@ http://purl.uniprot.org/uniprot/U5VPW4 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS36610 ^@ http://purl.uniprot.org/uniprot/U5W8P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1246995:AFR_RS08785 ^@ http://purl.uniprot.org/uniprot/U5VSR5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1246995:AFR_RS24535 ^@ http://purl.uniprot.org/uniprot/U5W208 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS28125 ^@ http://purl.uniprot.org/uniprot/U5W7D3 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1246995:AFR_RS35505 ^@ http://purl.uniprot.org/uniprot/U5WBJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1246995:AFR_RS01300 ^@ http://purl.uniprot.org/uniprot/U5VP35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04595 ^@ http://purl.uniprot.org/uniprot/U5VQW4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS09365 ^@ http://purl.uniprot.org/uniprot/U5VTG6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1246995:AFR_RS17065 ^@ http://purl.uniprot.org/uniprot/U5VXS1 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS40780 ^@ http://purl.uniprot.org/uniprot/U5WEB0 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1246995:AFR_RS07795 ^@ http://purl.uniprot.org/uniprot/U5VSN8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS09155 ^@ http://purl.uniprot.org/uniprot/U5VTD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS00945 ^@ http://purl.uniprot.org/uniprot/U5VNU6 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS10240 ^@ http://purl.uniprot.org/uniprot/U5VXD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS26240 ^@ http://purl.uniprot.org/uniprot/U5W386 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1246995:AFR_RS25685 ^@ http://purl.uniprot.org/uniprot/U5W2X7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the arabinose isomerase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of L-arabinose to L-ribulose. http://togogenome.org/gene/1246995:AFR_RS02600 ^@ http://purl.uniprot.org/uniprot/U5VPR9 ^@ Similarity ^@ Belongs to the EccD/Snm4 family. http://togogenome.org/gene/1246995:AFR_RS09445 ^@ http://purl.uniprot.org/uniprot/U5VWS0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS30075 ^@ http://purl.uniprot.org/uniprot/U5W8E5 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1246995:AFR_RS11730 ^@ http://purl.uniprot.org/uniprot/U5VY34 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1246995:AFR_RS11455 ^@ http://purl.uniprot.org/uniprot/U5VXZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS08705 ^@ http://purl.uniprot.org/uniprot/U5VT72 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS33670 ^@ http://purl.uniprot.org/uniprot/U5W7H1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS27060 ^@ http://purl.uniprot.org/uniprot/U5W3Q3 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1246995:AFR_RS01250 ^@ http://purl.uniprot.org/uniprot/U5VP12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1246995:AFR_RS31200 ^@ http://purl.uniprot.org/uniprot/U5W8Z7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1246995:AFR_RS28885 ^@ http://purl.uniprot.org/uniprot/U5W472 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS21850 ^@ http://purl.uniprot.org/uniprot/U5W078 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 39 family. http://togogenome.org/gene/1246995:AFR_RS43060 ^@ http://purl.uniprot.org/uniprot/U5WFK3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1246995:AFR_RS33340 ^@ http://purl.uniprot.org/uniprot/U5W7B2 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1246995:AFR_RS36390 ^@ http://purl.uniprot.org/uniprot/U5W8M9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS10145 ^@ http://purl.uniprot.org/uniprot/U5VU09 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1246995:AFR_RS31450 ^@ http://purl.uniprot.org/uniprot/U5W693 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS16995 ^@ http://purl.uniprot.org/uniprot/U5W120 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1246995:AFR_RS16730 ^@ http://purl.uniprot.org/uniprot/U5VXN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1246995:AFR_RS12985 ^@ http://purl.uniprot.org/uniprot/U5VVG6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/1246995:AFR_RS42885 ^@ http://purl.uniprot.org/uniprot/U5WFS6 ^@ Similarity ^@ Belongs to the fructosamine kinase family. http://togogenome.org/gene/1246995:AFR_RS41085 ^@ http://purl.uniprot.org/uniprot/U5WEQ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cell surface|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.|||capsule|||cell wall http://togogenome.org/gene/1246995:AFR_RS18830 ^@ http://purl.uniprot.org/uniprot/U5VYF1 ^@ Function ^@ Catalyzes the reduction of sulfite to sulfide, a step in the biosynthesis of sulfur-containing amino acids and cofactors. http://togogenome.org/gene/1246995:AFR_RS04720 ^@ http://purl.uniprot.org/uniprot/U5VQY8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS07110 ^@ http://purl.uniprot.org/uniprot/U5VRU9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the xylose isomerase family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS24125 ^@ http://purl.uniprot.org/uniprot/U5W1U1 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1246995:AFR_RS33240 ^@ http://purl.uniprot.org/uniprot/U5WAA4 ^@ Similarity ^@ Belongs to the UPF0225 family. http://togogenome.org/gene/1246995:AFR_RS20330 ^@ http://purl.uniprot.org/uniprot/U5VZI6 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1246995:AFR_RS39420 ^@ http://purl.uniprot.org/uniprot/U5WAG1 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1246995:AFR_RS16715 ^@ http://purl.uniprot.org/uniprot/U5W139 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS30380 ^@ http://purl.uniprot.org/uniprot/U5W8P1 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1246995:AFR_RS30510 ^@ http://purl.uniprot.org/uniprot/U5W5Q0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS14150 ^@ http://purl.uniprot.org/uniprot/U5VWE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39600 ^@ http://purl.uniprot.org/uniprot/U5WAW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS41755 ^@ http://purl.uniprot.org/uniprot/U5WBL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS13205 ^@ http://purl.uniprot.org/uniprot/U5VV74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS13430 ^@ http://purl.uniprot.org/uniprot/U5VVC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS31675 ^@ http://purl.uniprot.org/uniprot/U5W6F0 ^@ Function|||Similarity ^@ Belongs to the uricase family.|||Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. http://togogenome.org/gene/1246995:AFR_RS17830 ^@ http://purl.uniprot.org/uniprot/U5W1M1 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS35140 ^@ http://purl.uniprot.org/uniprot/U5W7R8 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS08600 ^@ http://purl.uniprot.org/uniprot/U5VWF0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS19355 ^@ http://purl.uniprot.org/uniprot/U5VYS9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1246995:AFR_RS06495 ^@ http://purl.uniprot.org/uniprot/U5VRK7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20 family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1246995:AFR_RS14425 ^@ http://purl.uniprot.org/uniprot/U5VWC1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS21605 ^@ http://purl.uniprot.org/uniprot/U5W0E2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS24965 ^@ http://purl.uniprot.org/uniprot/U5W5H0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS13650 ^@ http://purl.uniprot.org/uniprot/U5VVG7 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1246995:AFR_RS32665 ^@ http://purl.uniprot.org/uniprot/U5WA10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS27965 ^@ http://purl.uniprot.org/uniprot/U5W7A5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1246995:AFR_RS05820 ^@ http://purl.uniprot.org/uniprot/U5VUN1 ^@ Similarity ^@ Belongs to the EfeM/EfeO family. http://togogenome.org/gene/1246995:AFR_RS04535 ^@ http://purl.uniprot.org/uniprot/U5VTZ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1246995:AFR_RS31470 ^@ http://purl.uniprot.org/uniprot/U5W9A3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS37965 ^@ http://purl.uniprot.org/uniprot/U5W9C3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS41460 ^@ http://purl.uniprot.org/uniprot/U5WBH9 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1246995:AFR_RS39100 ^@ http://purl.uniprot.org/uniprot/U5WA62 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS31845 ^@ http://purl.uniprot.org/uniprot/U5W9L4 ^@ Similarity ^@ Belongs to the selenium-binding protein family. http://togogenome.org/gene/1246995:AFR_RS33720 ^@ http://purl.uniprot.org/uniprot/U5W7I2 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS08285 ^@ http://purl.uniprot.org/uniprot/U5VW87 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS30750 ^@ http://purl.uniprot.org/uniprot/U5W8R1 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/1246995:AFR_RS35100 ^@ http://purl.uniprot.org/uniprot/U5WB87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1246995:AFR_RS30285 ^@ http://purl.uniprot.org/uniprot/U5W5K3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS20900 ^@ http://purl.uniprot.org/uniprot/U5VZJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Gfo/Idh/MocA family.|||Homotetramer.|||Involved in the oxidation of myo-inositol (MI) to 2-keto-myo-inositol (2KMI or 2-inosose). http://togogenome.org/gene/1246995:AFR_RS36870 ^@ http://purl.uniprot.org/uniprot/U5WC78 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1246995:AFR_RS22880 ^@ http://purl.uniprot.org/uniprot/U5W4A5 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS40365 ^@ http://purl.uniprot.org/uniprot/U5WAP7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS31080 ^@ http://purl.uniprot.org/uniprot/U5W932 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1246995:AFR_RS38835 ^@ http://purl.uniprot.org/uniprot/U5WDF4 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS20210 ^@ http://purl.uniprot.org/uniprot/U5W2S1 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1246995:AFR_RS12790 ^@ http://purl.uniprot.org/uniprot/U5VYM4 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS39605 ^@ http://purl.uniprot.org/uniprot/U5WAC4 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1246995:AFR_RS30785 ^@ http://purl.uniprot.org/uniprot/U5W5U9 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1246995:AFR_RS18800 ^@ http://purl.uniprot.org/uniprot/U5VYN9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05815 ^@ http://purl.uniprot.org/uniprot/U5VRF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS09685 ^@ http://purl.uniprot.org/uniprot/U5VTL5 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1246995:AFR_RS29165 ^@ http://purl.uniprot.org/uniprot/U5W7X9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS29775 ^@ http://purl.uniprot.org/uniprot/U5W890 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/1246995:AFR_RS33175 ^@ http://purl.uniprot.org/uniprot/U5W6M3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1246995:AFR_RS29140 ^@ http://purl.uniprot.org/uniprot/U5W7X6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04520 ^@ http://purl.uniprot.org/uniprot/U5VQU8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS04580 ^@ http://purl.uniprot.org/uniprot/U5VQT0 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1246995:AFR_RS36325 ^@ http://purl.uniprot.org/uniprot/U5WBV9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS20180 ^@ http://purl.uniprot.org/uniprot/U5VZF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS29570 ^@ http://purl.uniprot.org/uniprot/U5W8A2 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS32580 ^@ http://purl.uniprot.org/uniprot/U5W6G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1246995:AFR_RS35865 ^@ http://purl.uniprot.org/uniprot/U5W849 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS06085 ^@ http://purl.uniprot.org/uniprot/U5VV09 ^@ Similarity ^@ Belongs to the peptidase M7 family. http://togogenome.org/gene/1246995:AFR_RS30765 ^@ http://purl.uniprot.org/uniprot/U5W587 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS41600 ^@ http://purl.uniprot.org/uniprot/U5WC15 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1246995:AFR_RS05795 ^@ http://purl.uniprot.org/uniprot/U5VUM8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS31640 ^@ http://purl.uniprot.org/uniprot/U5W9B8 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/1246995:AFR_RS35530 ^@ http://purl.uniprot.org/uniprot/U5WBJ7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/1246995:AFR_RS37515 ^@ http://purl.uniprot.org/uniprot/U5W9A1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1246995:AFR_RS34140 ^@ http://purl.uniprot.org/uniprot/U5WAV5 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1246995:AFR_RS35690 ^@ http://purl.uniprot.org/uniprot/U5W814 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1246995:AFR_RS19360 ^@ http://purl.uniprot.org/uniprot/U5VXL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1246995:AFR_RS30065 ^@ http://purl.uniprot.org/uniprot/U5W4W2 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1246995:AFR_RS10700 ^@ http://purl.uniprot.org/uniprot/U5VU61 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS23345 ^@ http://purl.uniprot.org/uniprot/U5W1K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS37670 ^@ http://purl.uniprot.org/uniprot/U5WCM0 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1246995:AFR_RS11015 ^@ http://purl.uniprot.org/uniprot/U5VUH7 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1246995:AFR_RS23190 ^@ http://purl.uniprot.org/uniprot/U5W4L3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37985 ^@ http://purl.uniprot.org/uniprot/U5W9W5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS10715 ^@ http://purl.uniprot.org/uniprot/U5VUB5 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1246995:AFR_RS05960 ^@ http://purl.uniprot.org/uniprot/U5VRM1 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/1246995:AFR_RS20870 ^@ http://purl.uniprot.org/uniprot/U5W055 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1246995:AFR_RS09010 ^@ http://purl.uniprot.org/uniprot/U5VTG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS16985 ^@ http://purl.uniprot.org/uniprot/U5VXF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS15880 ^@ http://purl.uniprot.org/uniprot/U5W0I2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the polysaccharide lyase 1 family.|||Secreted http://togogenome.org/gene/1246995:AFR_RS40475 ^@ http://purl.uniprot.org/uniprot/U5WE55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1246995:AFR_RS16980 ^@ http://purl.uniprot.org/uniprot/U5VXZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS00910 ^@ http://purl.uniprot.org/uniprot/U5VRU8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the IPP isomerase type 1 family.|||Binds 1 Mg(2+) ion per subunit. The magnesium ion binds only when substrate is bound.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS18135 ^@ http://purl.uniprot.org/uniprot/U5W1S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS35795 ^@ http://purl.uniprot.org/uniprot/U5W8A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS33855 ^@ http://purl.uniprot.org/uniprot/U5W781 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1246995:AFR_RS03235 ^@ http://purl.uniprot.org/uniprot/U5VQ35 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS18010 ^@ http://purl.uniprot.org/uniprot/U5W1J6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS40500 ^@ http://purl.uniprot.org/uniprot/U5WE59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12805 ^@ http://purl.uniprot.org/uniprot/U5VV02 ^@ Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. http://togogenome.org/gene/1246995:AFR_RS30630 ^@ http://purl.uniprot.org/uniprot/U5W8T6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PRA-PH family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS38820 ^@ http://purl.uniprot.org/uniprot/U5W9U8 ^@ Function ^@ Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. http://togogenome.org/gene/1246995:AFR_RS22825 ^@ http://purl.uniprot.org/uniprot/U5W0Y2 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1246995:AFR_RS10805 ^@ http://purl.uniprot.org/uniprot/U5VXG8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS14600 ^@ http://purl.uniprot.org/uniprot/U5VWE9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS21840 ^@ http://purl.uniprot.org/uniprot/U5W3X0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS35610 ^@ http://purl.uniprot.org/uniprot/U5W8K9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1246995:AFR_RS30490 ^@ http://purl.uniprot.org/uniprot/U5W531 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS00715 ^@ http://purl.uniprot.org/uniprot/U5VNQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07955 ^@ http://purl.uniprot.org/uniprot/U5VSL8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS41010 ^@ http://purl.uniprot.org/uniprot/U5WEP2 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS16915 ^@ http://purl.uniprot.org/uniprot/U5VXP7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS02950 ^@ http://purl.uniprot.org/uniprot/U5VPY8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS15015 ^@ http://purl.uniprot.org/uniprot/U5VW94 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS21250 ^@ http://purl.uniprot.org/uniprot/U5VZS0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1246995:AFR_RS24685 ^@ http://purl.uniprot.org/uniprot/U5W226 ^@ Similarity ^@ Belongs to the DszC flavin monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS09345 ^@ http://purl.uniprot.org/uniprot/U5VWQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS05230 ^@ http://purl.uniprot.org/uniprot/U5VR47 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1246995:AFR_RS04385 ^@ http://purl.uniprot.org/uniprot/U5VQE9 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS23450 ^@ http://purl.uniprot.org/uniprot/U5W0Y9 ^@ Similarity ^@ Belongs to the acyl-CoA oxidase family. http://togogenome.org/gene/1246995:AFR_RS15550 ^@ http://purl.uniprot.org/uniprot/U5W070 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS00535 ^@ http://purl.uniprot.org/uniprot/U5VNM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1246995:AFR_RS38960 ^@ http://purl.uniprot.org/uniprot/U5WDH8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS14845 ^@ http://purl.uniprot.org/uniprot/U5VW65 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS07930 ^@ http://purl.uniprot.org/uniprot/U5VSL2 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1246995:AFR_RS02135 ^@ http://purl.uniprot.org/uniprot/U5VSL4 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1246995:AFR_RS04465 ^@ http://purl.uniprot.org/uniprot/U5VU68 ^@ Similarity ^@ Belongs to the UPF0336 family. http://togogenome.org/gene/1246995:AFR_RS08850 ^@ http://purl.uniprot.org/uniprot/U5VWN6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS17240 ^@ http://purl.uniprot.org/uniprot/U5VXU7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 27 family. http://togogenome.org/gene/1246995:AFR_RS06445 ^@ http://purl.uniprot.org/uniprot/U5VRJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1246995:AFR_RS13435 ^@ http://purl.uniprot.org/uniprot/U5VVQ1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS27895 ^@ http://purl.uniprot.org/uniprot/U5W469 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS04610 ^@ http://purl.uniprot.org/uniprot/U5VU12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1246995:AFR_RS30590 ^@ http://purl.uniprot.org/uniprot/U5W550 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1246995:AFR_RS01730 ^@ http://purl.uniprot.org/uniprot/U5VSD8 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1246995:AFR_RS37285 ^@ http://purl.uniprot.org/uniprot/U5W908 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS22170 ^@ http://purl.uniprot.org/uniprot/U5W0C8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NRAMP family.|||Cell membrane|||H(+)-stimulated, divalent metal cation uptake system. http://togogenome.org/gene/1246995:AFR_RS35255 ^@ http://purl.uniprot.org/uniprot/U5WBF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS05305 ^@ http://purl.uniprot.org/uniprot/U5VR62 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS08270 ^@ http://purl.uniprot.org/uniprot/U5VSE8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1246995:AFR_RS40185 ^@ http://purl.uniprot.org/uniprot/U5WB88 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1246995:AFR_RS16440 ^@ http://purl.uniprot.org/uniprot/U5VX75 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS08100 ^@ http://purl.uniprot.org/uniprot/U5VSB4 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1246995:AFR_RS33235 ^@ http://purl.uniprot.org/uniprot/U5WA63 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS31900 ^@ http://purl.uniprot.org/uniprot/U5W6I4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS02340 ^@ http://purl.uniprot.org/uniprot/U5VSX2 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1246995:AFR_RS34745 ^@ http://purl.uniprot.org/uniprot/U5W835 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS15060 ^@ http://purl.uniprot.org/uniprot/U5VWW0 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 Fe cation per subunit.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS10660 ^@ http://purl.uniprot.org/uniprot/U5VXK8 ^@ Function|||Similarity ^@ Belongs to the WhiA family.|||Involved in cell division and chromosome segregation. http://togogenome.org/gene/1246995:AFR_RS41955 ^@ http://purl.uniprot.org/uniprot/U5WBP4 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids lysine, threonine, isoleucine and methionine. http://togogenome.org/gene/1246995:AFR_RS26635 ^@ http://purl.uniprot.org/uniprot/U5W3I2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS30255 ^@ http://purl.uniprot.org/uniprot/U5W8M0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS10415 ^@ http://purl.uniprot.org/uniprot/U5VU65 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1246995:AFR_RS09795 ^@ http://purl.uniprot.org/uniprot/U5VX46 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1246995:AFR_RS03425 ^@ http://purl.uniprot.org/uniprot/U5VTA3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS10045 ^@ http://purl.uniprot.org/uniprot/U5VX88 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS38205 ^@ http://purl.uniprot.org/uniprot/U5WD34 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AB hydrolase superfamily.|||Periplasm http://togogenome.org/gene/1246995:AFR_RS14660 ^@ http://purl.uniprot.org/uniprot/U5VZW7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.|||Belongs to the azoreductase type 1 family.|||Binds 1 FMN per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones. http://togogenome.org/gene/1246995:AFR_RS07790 ^@ http://purl.uniprot.org/uniprot/U5VVZ7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1246995:AFR_RS25450 ^@ http://purl.uniprot.org/uniprot/U5W5V7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS32100 ^@ http://purl.uniprot.org/uniprot/U5W6M1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1246995:AFR_RS21415 ^@ http://purl.uniprot.org/uniprot/U5W3K3 ^@ Similarity ^@ Belongs to the IucA/IucC family. http://togogenome.org/gene/1246995:AFR_RS22520 ^@ http://purl.uniprot.org/uniprot/U5W0J0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS39680 ^@ http://purl.uniprot.org/uniprot/U5WAD8 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/1246995:AFR_RS28260 ^@ http://purl.uniprot.org/uniprot/U5W3U1 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS29400 ^@ http://purl.uniprot.org/uniprot/U5W533 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1246995:AFR_RS36765 ^@ http://purl.uniprot.org/uniprot/U5W8X9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1246995:AFR_RS22940 ^@ http://purl.uniprot.org/uniprot/U5W1D4 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS42720 ^@ http://purl.uniprot.org/uniprot/U5WC23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS03165 ^@ http://purl.uniprot.org/uniprot/U5VPM2 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS36790 ^@ http://purl.uniprot.org/uniprot/U5W8Y3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS42815 ^@ http://purl.uniprot.org/uniprot/U5WCS1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer. http://togogenome.org/gene/1246995:AFR_RS11815 ^@ http://purl.uniprot.org/uniprot/U5VV12 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1246995:AFR_RS43115 ^@ http://purl.uniprot.org/uniprot/U5WCX6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS20050 ^@ http://purl.uniprot.org/uniprot/U5VZ43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30040 ^@ http://purl.uniprot.org/uniprot/U5W4W0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS11325 ^@ http://purl.uniprot.org/uniprot/U5VUI9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1246995:AFR_RS04645 ^@ http://purl.uniprot.org/uniprot/U5VQX4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1246995:AFR_RS09150 ^@ http://purl.uniprot.org/uniprot/U5VT16 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1246995:AFR_RS42725 ^@ http://purl.uniprot.org/uniprot/U5WC74 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/1246995:AFR_RS08180 ^@ http://purl.uniprot.org/uniprot/U5VW02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS32970 ^@ http://purl.uniprot.org/uniprot/U5WA59 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1246995:AFR_RS27575 ^@ http://purl.uniprot.org/uniprot/U5W3G4 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1246995:AFR_RS26605 ^@ http://purl.uniprot.org/uniprot/U5W6L5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS18735 ^@ http://purl.uniprot.org/uniprot/U5W229 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS10515 ^@ http://purl.uniprot.org/uniprot/U5VU80 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1246995:AFR_RS33400 ^@ http://purl.uniprot.org/uniprot/U5W6S6 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1246995:AFR_RS11380 ^@ http://purl.uniprot.org/uniprot/U5VXX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the Ro 60 kDa family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS25585 ^@ http://purl.uniprot.org/uniprot/U5W2V9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS08865 ^@ http://purl.uniprot.org/uniprot/U5VT86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS45830 ^@ http://purl.uniprot.org/uniprot/U5VQN1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37215 ^@ http://purl.uniprot.org/uniprot/U5W953 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF alpha-subunit/FixB family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1246995:AFR_RS09990 ^@ http://purl.uniprot.org/uniprot/U5VX19 ^@ Function|||Similarity ^@ Belongs to the DNA polymerase type-Y family.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1246995:AFR_RS25440 ^@ http://purl.uniprot.org/uniprot/U5W2G4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS16315 ^@ http://purl.uniprot.org/uniprot/U5VXK6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS37610 ^@ http://purl.uniprot.org/uniprot/U5W962 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1246995:AFR_RS21925 ^@ http://purl.uniprot.org/uniprot/U5W088 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1246995:AFR_RS38665 ^@ http://purl.uniprot.org/uniprot/U5WA92 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS35435 ^@ http://purl.uniprot.org/uniprot/U5W8H6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS06070 ^@ http://purl.uniprot.org/uniprot/U5VR88 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1246995:AFR_RS26230 ^@ http://purl.uniprot.org/uniprot/U5W6A4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM175 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS41000 ^@ http://purl.uniprot.org/uniprot/U5WB89 ^@ Similarity ^@ Belongs to the PhoU family.|||Belongs to the UPF0111 family. http://togogenome.org/gene/1246995:AFR_RS23125 ^@ http://purl.uniprot.org/uniprot/U5W141 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/1246995:AFR_RS34345 ^@ http://purl.uniprot.org/uniprot/U5W7E0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1246995:AFR_RS10785 ^@ http://purl.uniprot.org/uniprot/U5VXN1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily. http://togogenome.org/gene/1246995:AFR_RS41305 ^@ http://purl.uniprot.org/uniprot/U5WBF4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1246995:AFR_RS09520 ^@ http://purl.uniprot.org/uniprot/U5VWT2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS41140 ^@ http://purl.uniprot.org/uniprot/U5WBR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS04510 ^@ http://purl.uniprot.org/uniprot/U5VTZ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1246995:AFR_RS14560 ^@ http://purl.uniprot.org/uniprot/U5VZV0 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS40890 ^@ http://purl.uniprot.org/uniprot/U5WBM0 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1246995:AFR_RS34235 ^@ http://purl.uniprot.org/uniprot/U5WAW9 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. http://togogenome.org/gene/1246995:AFR_RS26535 ^@ http://purl.uniprot.org/uniprot/U5W3G5 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped by the proteasome-associated ATPase, ARC.|||The formation of the proteasomal ATPase ARC-20S proteasome complex, likely via the docking of the C-termini of ARC into the intersubunit pockets in the alpha-rings, may trigger opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1246995:AFR_RS28065 ^@ http://purl.uniprot.org/uniprot/U5W783 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/1246995:AFR_RS05765 ^@ http://purl.uniprot.org/uniprot/U5VRE4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS09510 ^@ http://purl.uniprot.org/uniprot/U5VT71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Associates with subunits I, II and III to form cytochrome c oxidase.|||Belongs to the cytochrome c oxidase bacterial subunit CtaF family.|||Cell membrane|||Membrane|||Part of cytochrome c oxidase, its function is unknown. http://togogenome.org/gene/1246995:AFR_RS15290 ^@ http://purl.uniprot.org/uniprot/U5VWE2 ^@ Similarity ^@ Belongs to the bacterial phospholipase C family. http://togogenome.org/gene/1246995:AFR_RS30290 ^@ http://purl.uniprot.org/uniprot/U5W4Z4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39460 ^@ http://purl.uniprot.org/uniprot/U5WA99 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS14450 ^@ http://purl.uniprot.org/uniprot/U5VWC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS08220 ^@ http://purl.uniprot.org/uniprot/U5VSD9 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1246995:AFR_RS08135 ^@ http://purl.uniprot.org/uniprot/U5VW59 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30545 ^@ http://purl.uniprot.org/uniprot/U5W5B6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS16815 ^@ http://purl.uniprot.org/uniprot/U5VXN2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1246995:AFR_RS38765 ^@ http://purl.uniprot.org/uniprot/U5WAB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the beta sliding clamp family.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS44050 ^@ http://purl.uniprot.org/uniprot/U5W4Q0 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS00010 ^@ http://purl.uniprot.org/uniprot/U5VRK6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1246995:AFR_RS32185 ^@ http://purl.uniprot.org/uniprot/U5W6N5 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-3 family. http://togogenome.org/gene/1246995:AFR_RS35850 ^@ http://purl.uniprot.org/uniprot/U5WBL6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1246995:AFR_RS04325 ^@ http://purl.uniprot.org/uniprot/U5VU47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS12225 ^@ http://purl.uniprot.org/uniprot/U5VYI5 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1246995:AFR_RS09385 ^@ http://purl.uniprot.org/uniprot/U5VT53 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1246995:AFR_RS30640 ^@ http://purl.uniprot.org/uniprot/U5W561 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS04300 ^@ http://purl.uniprot.org/uniprot/U5VU42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS23220 ^@ http://purl.uniprot.org/uniprot/U5W1I1 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1246995:AFR_RS43070 ^@ http://purl.uniprot.org/uniprot/U5WCW8 ^@ Similarity ^@ Belongs to the AP endonuclease 2 family. http://togogenome.org/gene/1246995:AFR_RS06250 ^@ http://purl.uniprot.org/uniprot/U5VRN6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS38825 ^@ http://purl.uniprot.org/uniprot/U5WA11 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. EgtD family.|||Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine.|||Monomer. http://togogenome.org/gene/1246995:AFR_RS40110 ^@ http://purl.uniprot.org/uniprot/U5WE85 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1246995:AFR_RS20310 ^@ http://purl.uniprot.org/uniprot/U5W2T7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS00075 ^@ http://purl.uniprot.org/uniprot/U5VMV4 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1246995:AFR_RS21650 ^@ http://purl.uniprot.org/uniprot/U5W0Q3 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1246995:AFR_RS20745 ^@ http://purl.uniprot.org/uniprot/U5W031 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1246995:AFR_RS40160 ^@ http://purl.uniprot.org/uniprot/U5WE93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS15850 ^@ http://purl.uniprot.org/uniprot/U5W0C0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS24585 ^@ http://purl.uniprot.org/uniprot/U5W216 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS28600 ^@ http://purl.uniprot.org/uniprot/U5W7N0 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1246995:AFR_RS03460 ^@ http://purl.uniprot.org/uniprot/U5VQ79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1246995:AFR_RS40675 ^@ http://purl.uniprot.org/uniprot/U5WB24 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1246995:AFR_RS19510 ^@ http://purl.uniprot.org/uniprot/U5VZ52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS30150 ^@ http://purl.uniprot.org/uniprot/U5W8F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS40720 ^@ http://purl.uniprot.org/uniprot/U5WAW1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1246995:AFR_RS36240 ^@ http://purl.uniprot.org/uniprot/U5W8D1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS02625 ^@ http://purl.uniprot.org/uniprot/U5VPS4 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS05850 ^@ http://purl.uniprot.org/uniprot/U5VUW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1246995:AFR_RS24275 ^@ http://purl.uniprot.org/uniprot/U5W1W6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS41355 ^@ http://purl.uniprot.org/uniprot/U5WBG2 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1246995:AFR_RS05755 ^@ http://purl.uniprot.org/uniprot/U5VRI0 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS33920 ^@ http://purl.uniprot.org/uniprot/U5W7M7 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1246995:AFR_RS20125 ^@ http://purl.uniprot.org/uniprot/U5VZ55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS17265 ^@ http://purl.uniprot.org/uniprot/U5VXV2 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS36385 ^@ http://purl.uniprot.org/uniprot/U5W8G2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS08685 ^@ http://purl.uniprot.org/uniprot/U5VSP2 ^@ Similarity ^@ Belongs to the SurE nucleotidase family. http://togogenome.org/gene/1246995:AFR_RS30680 ^@ http://purl.uniprot.org/uniprot/U5W8U5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS04865 ^@ http://purl.uniprot.org/uniprot/U5VUD7 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS00400 ^@ http://purl.uniprot.org/uniprot/U5VRS6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Bifunctional enzyme that catalyzes both the deamination of dCTP to dUTP and the hydrolysis of dUTP to dUMP without releasing the toxic dUTP intermediate.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS07910 ^@ http://purl.uniprot.org/uniprot/U5VVV1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1246995:AFR_RS26570 ^@ http://purl.uniprot.org/uniprot/U5W371 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.|||Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.|||Homotetramer composed of a dimer of dimers. http://togogenome.org/gene/1246995:AFR_RS27090 ^@ http://purl.uniprot.org/uniprot/U5W368 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1246995:AFR_RS05145 ^@ http://purl.uniprot.org/uniprot/U5VR69 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1246995:AFR_RS07425 ^@ http://purl.uniprot.org/uniprot/U5VVT5 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SURF1 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS22295 ^@ http://purl.uniprot.org/uniprot/U5W0F4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS38795 ^@ http://purl.uniprot.org/uniprot/U5W9U2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1246995:AFR_RS21395 ^@ http://purl.uniprot.org/uniprot/U5W0F8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1246995:AFR_RS37075 ^@ http://purl.uniprot.org/uniprot/U5W9D9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1246995:AFR_RS23550 ^@ http://purl.uniprot.org/uniprot/U5W1C8 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/1246995:AFR_RS12515 ^@ http://purl.uniprot.org/uniprot/U5VYI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS36370 ^@ http://purl.uniprot.org/uniprot/U5WBW9 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1246995:AFR_RS12900 ^@ http://purl.uniprot.org/uniprot/U5VVL3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS10565 ^@ http://purl.uniprot.org/uniprot/U5VU89 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1246995:AFR_RS20225 ^@ http://purl.uniprot.org/uniprot/U5VZ71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS27485 ^@ http://purl.uniprot.org/uniprot/U5W6X5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS06575 ^@ http://purl.uniprot.org/uniprot/U5VRL9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS25695 ^@ http://purl.uniprot.org/uniprot/U5W2L5 ^@ Similarity ^@ Belongs to the ribulokinase family. http://togogenome.org/gene/1246995:AFR_RS36235 ^@ http://purl.uniprot.org/uniprot/U5W8X3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1246995:AFR_RS04600 ^@ http://purl.uniprot.org/uniprot/U5VQH5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1246995:AFR_RS37500 ^@ http://purl.uniprot.org/uniprot/U5WCR4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS33530 ^@ http://purl.uniprot.org/uniprot/U5WAB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS21815 ^@ http://purl.uniprot.org/uniprot/U5W3W6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS46695 ^@ http://purl.uniprot.org/uniprot/U5VSM2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1246995:AFR_RS04555 ^@ http://purl.uniprot.org/uniprot/U5VQS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1246995:AFR_RS15025 ^@ http://purl.uniprot.org/uniprot/U5VZX4 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1246995:AFR_RS01880 ^@ http://purl.uniprot.org/uniprot/U5VSG8 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1246995:AFR_RS22970 ^@ http://purl.uniprot.org/uniprot/U5W0R0 ^@ Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-69 and Arg-72) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. http://togogenome.org/gene/1246995:AFR_RS10780 ^@ http://purl.uniprot.org/uniprot/U5VXG4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1246995:AFR_RS16920 ^@ http://purl.uniprot.org/uniprot/U5W105 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1246995:AFR_RS01460 ^@ http://purl.uniprot.org/uniprot/U5VSG9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS05010 ^@ http://purl.uniprot.org/uniprot/U5VU86 ^@ Similarity ^@ Belongs to the IMPDH/GMPR family. http://togogenome.org/gene/1246995:AFR_RS26545 ^@ http://purl.uniprot.org/uniprot/U5W367 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the prokaryotic ubiquitin-like protein family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation.|||Strongly interacts with the proteasome-associated ATPase ARC through a hydrophobic interface; the interacting region of Pup lies in its C-terminal half. There is one Pup binding site per ARC hexamer ring.|||The N-terminal unstructured half of Pup provides a signal required to initiate unfolding and degradation by the proteasome but is not needed for pupylation, while the C-terminal helical half of Pup interacts with ARC to target proteins to the proteasome. http://togogenome.org/gene/1246995:AFR_RS14245 ^@ http://purl.uniprot.org/uniprot/U5VW93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS36130 ^@ http://purl.uniprot.org/uniprot/U5WBW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS01175 ^@ http://purl.uniprot.org/uniprot/U5VNZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS39810 ^@ http://purl.uniprot.org/uniprot/U5WAM3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS27520 ^@ http://purl.uniprot.org/uniprot/U5W3Z2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS30835 ^@ http://purl.uniprot.org/uniprot/U5W5W0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1246995:AFR_RS08985 ^@ http://purl.uniprot.org/uniprot/U5VTG4 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1246995:AFR_RS15355 ^@ http://purl.uniprot.org/uniprot/U5W089 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS09180 ^@ http://purl.uniprot.org/uniprot/U5VTD5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07475 ^@ http://purl.uniprot.org/uniprot/U5VSH5 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1246995:AFR_RS36485 ^@ http://purl.uniprot.org/uniprot/U5W8I4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1246995:AFR_RS30385 ^@ http://purl.uniprot.org/uniprot/U5W5M4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS04705 ^@ http://purl.uniprot.org/uniprot/U5VQV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1246995:AFR_RS04945 ^@ http://purl.uniprot.org/uniprot/U5VR30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS35855 ^@ http://purl.uniprot.org/uniprot/U5WBQ4 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1246995:AFR_RS41320 ^@ http://purl.uniprot.org/uniprot/U5WBV4 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1246995:AFR_RS09140 ^@ http://purl.uniprot.org/uniprot/U5VWT6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1246995:AFR_RS23030 ^@ http://purl.uniprot.org/uniprot/U5W4C8 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS09215 ^@ http://purl.uniprot.org/uniprot/U5VTD8 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS41590 ^@ http://purl.uniprot.org/uniprot/U5WER2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate, the first step in the de novo biosynthesis of NAD(+).|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS03300 ^@ http://purl.uniprot.org/uniprot/U5VT82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS06095 ^@ http://purl.uniprot.org/uniprot/U5VR93 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1246995:AFR_RS31215 ^@ http://purl.uniprot.org/uniprot/U5W5J0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1246995:AFR_RS30775 ^@ http://purl.uniprot.org/uniprot/U5W8R7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1246995:AFR_RS21390 ^@ http://purl.uniprot.org/uniprot/U5W3J8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS19860 ^@ http://purl.uniprot.org/uniprot/U5W2K4 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1246995:AFR_RS31340 ^@ http://purl.uniprot.org/uniprot/U5W5T0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1246995:AFR_RS27070 ^@ http://purl.uniprot.org/uniprot/U5W3F5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS41615 ^@ http://purl.uniprot.org/uniprot/U5WET9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1246995:AFR_RS42625 ^@ http://purl.uniprot.org/uniprot/U5WC56 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1246995:AFR_RS38770 ^@ http://purl.uniprot.org/uniprot/U5W9T7 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/1246995:AFR_RS21675 ^@ http://purl.uniprot.org/uniprot/U5W0Q7 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1246995:AFR_RS24185 ^@ http://purl.uniprot.org/uniprot/U5W592 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS40705 ^@ http://purl.uniprot.org/uniprot/U5WE98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS44210 ^@ http://purl.uniprot.org/uniprot/U5W755 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1246995:AFR_RS15770 ^@ http://purl.uniprot.org/uniprot/U5VX22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1246995:AFR_RS30805 ^@ http://purl.uniprot.org/uniprot/U5W8X2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1246995:AFR_RS03095 ^@ http://purl.uniprot.org/uniprot/U5VPK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS07890 ^@ http://purl.uniprot.org/uniprot/U5VW13 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1246995:AFR_RS22510 ^@ http://purl.uniprot.org/uniprot/U5W4A0 ^@ Similarity ^@ Belongs to the NtaA/SnaA/DszA monooxygenase family. http://togogenome.org/gene/1246995:AFR_RS14950 ^@ http://purl.uniprot.org/uniprot/U5VZW0 ^@ Similarity ^@ Belongs to the AfsR/DnrI/RedD regulatory family. http://togogenome.org/gene/1246995:AFR_RS42440 ^@ http://purl.uniprot.org/uniprot/U5WFK0 ^@ Similarity ^@ Belongs to the UPF0098 family. http://togogenome.org/gene/1246995:AFR_RS19990 ^@ http://purl.uniprot.org/uniprot/U5W2U4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1246995:AFR_RS36015 ^@ http://purl.uniprot.org/uniprot/U5W883 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1246995:AFR_RS08775 ^@ http://purl.uniprot.org/uniprot/U5VWI6 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1246995:AFR_RS09765 ^@ http://purl.uniprot.org/uniprot/U5VWX8 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/1246995:AFR_RS07115 ^@ http://purl.uniprot.org/uniprot/U5VS64 ^@ Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate. http://togogenome.org/gene/1246995:AFR_RS05730 ^@ http://purl.uniprot.org/uniprot/U5VRH5 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Acts as a transcriptional regulator. Probably redox-responsive. The apo- but not holo-form probably binds DNA.|||Belongs to the WhiB family.|||Binds 1 [4Fe-4S] cluster per subunit. Following nitrosylation of the [4Fe-4S] cluster binds 1 [4Fe-8(NO)] cluster per subunit.|||Cytoplasm|||The Fe-S cluster can be nitrosylated by nitric oxide (NO).|||Upon Fe-S cluster removal intramolecular disulfide bonds are formed. http://togogenome.org/gene/1246995:AFR_RS01370 ^@ http://purl.uniprot.org/uniprot/U5VNP9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS41060 ^@ http://purl.uniprot.org/uniprot/U5WEQ2 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS30395 ^@ http://purl.uniprot.org/uniprot/U5W585 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1246995:AFR_RS36020 ^@ http://purl.uniprot.org/uniprot/U5W8F5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1246995:AFR_RS24715 ^@ http://purl.uniprot.org/uniprot/U5W5C2 ^@ Similarity ^@ Belongs to the DAMOX/DASOX family. http://togogenome.org/gene/1246995:AFR_RS24650 ^@ http://purl.uniprot.org/uniprot/U5W2C6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/1246995:AFR_RS19055 ^@ http://purl.uniprot.org/uniprot/U5VYX7 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS43100 ^@ http://purl.uniprot.org/uniprot/U5WCE4 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1246995:AFR_RS21230 ^@ http://purl.uniprot.org/uniprot/U5W020 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS37545 ^@ http://purl.uniprot.org/uniprot/U5WCJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1246995:AFR_RS25415 ^@ http://purl.uniprot.org/uniprot/U5W2F9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1246995:AFR_RS05380 ^@ http://purl.uniprot.org/uniprot/U5VR77 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1246995:AFR_RS31445 ^@ http://purl.uniprot.org/uniprot/U5W998 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1246995:AFR_RS07380 ^@ http://purl.uniprot.org/uniprot/U5VSF7 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. http://togogenome.org/gene/1246995:AFR_RS11155 ^@ http://purl.uniprot.org/uniprot/U5VXN8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Cytoplasm|||Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1246995:AFR_RS00015 ^@ http://purl.uniprot.org/uniprot/U5VNB3 ^@ Similarity ^@ Belongs to the 6-phosphogluconate dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS19895 ^@ http://purl.uniprot.org/uniprot/U5VZL9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS20370 ^@ http://purl.uniprot.org/uniprot/U5VZW5 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1246995:AFR_RS37235 ^@ http://purl.uniprot.org/uniprot/U5W901 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS41885 ^@ http://purl.uniprot.org/uniprot/U5WF05 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1246995:AFR_RS32575 ^@ http://purl.uniprot.org/uniprot/U5W6B8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS07070 ^@ http://purl.uniprot.org/uniprot/U5VVF1 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1246995:AFR_RS08210 ^@ http://purl.uniprot.org/uniprot/U5VW72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS38440 ^@ http://purl.uniprot.org/uniprot/U5W9T5 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/1246995:AFR_RS07685 ^@ http://purl.uniprot.org/uniprot/U5VVQ9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1246995:AFR_RS35585 ^@ http://purl.uniprot.org/uniprot/U5W8K5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS10360 ^@ http://purl.uniprot.org/uniprot/U5VX86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1246995:AFR_RS09395 ^@ http://purl.uniprot.org/uniprot/U5VWR0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1246995:AFR_RS14525 ^@ http://purl.uniprot.org/uniprot/U5VWD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS42595 ^@ http://purl.uniprot.org/uniprot/U5WC03 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1246995:AFR_RS37220 ^@ http://purl.uniprot.org/uniprot/U5WCD7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ETF beta-subunit/FixA family.|||Heterodimer of an alpha and a beta subunit.|||The electron transfer flavoprotein serves as a specific electron acceptor for other dehydrogenases. It transfers the electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase). http://togogenome.org/gene/1246995:AFR_RS03550 ^@ http://purl.uniprot.org/uniprot/U5VTC6 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/1246995:AFR_RS27660 ^@ http://purl.uniprot.org/uniprot/U5W708 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1246995:AFR_RS39905 ^@ http://purl.uniprot.org/uniprot/U5WAI0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1246995:AFR_RS27205 ^@ http://purl.uniprot.org/uniprot/U5W3T0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS42645 ^@ http://purl.uniprot.org/uniprot/U5WC13 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1246995:AFR_RS20315 ^@ http://purl.uniprot.org/uniprot/U5W2Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS10685 ^@ http://purl.uniprot.org/uniprot/U5VXL3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase-binding protein RbpA family.|||Bind 1 Zn(2+) per subunit.|||Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters.|||Forms a complex with the RNAP catalytic core and with free principal sigma factors. http://togogenome.org/gene/1246995:AFR_RS04425 ^@ http://purl.uniprot.org/uniprot/U5VTX8 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1246995:AFR_RS01085 ^@ http://purl.uniprot.org/uniprot/U5VS51 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS31110 ^@ http://purl.uniprot.org/uniprot/U5W611 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS24520 ^@ http://purl.uniprot.org/uniprot/U5W5F1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS36415 ^@ http://purl.uniprot.org/uniprot/U5W8N3 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1246995:AFR_RS07650 ^@ http://purl.uniprot.org/uniprot/U5VVX5 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1246995:AFR_RS13365 ^@ http://purl.uniprot.org/uniprot/U5VYY0 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS33775 ^@ http://purl.uniprot.org/uniprot/U5W706 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1246995:AFR_RS23775 ^@ http://purl.uniprot.org/uniprot/U5W160 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1246995:AFR_RS33155 ^@ http://purl.uniprot.org/uniprot/U5W6T2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1246995:AFR_RS21235 ^@ http://purl.uniprot.org/uniprot/U5W3B1 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/1246995:AFR_RS35520 ^@ http://purl.uniprot.org/uniprot/U5W853 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1246995:AFR_RS00630 ^@ http://purl.uniprot.org/uniprot/U5VN61 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1246995:AFR_RS11190 ^@ http://purl.uniprot.org/uniprot/U5VXV7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1246995:AFR_RS30605 ^@ http://purl.uniprot.org/uniprot/U5W8T1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1246995:AFR_RS26825 ^@ http://purl.uniprot.org/uniprot/U5W6Q5 ^@ Similarity|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Homohexamer. The oligomerization is ATP-dependent. http://togogenome.org/gene/1246995:AFR_RS15895 ^@ http://purl.uniprot.org/uniprot/U5VX44 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1246995:AFR_RS37170 ^@ http://purl.uniprot.org/uniprot/U5WCC6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1246995:AFR_RS36025 ^@ http://purl.uniprot.org/uniprot/U5WBP5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1246995:AFR_RS05785 ^@ http://purl.uniprot.org/uniprot/U5VR32 ^@ Similarity ^@ Belongs to the UPF0434 family. http://togogenome.org/gene/1246995:AFR_RS24070 ^@ http://purl.uniprot.org/uniprot/U5W1I3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1246995:AFR_RS13915 ^@ http://purl.uniprot.org/uniprot/U5VZC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1246995:AFR_RS31270 ^@ http://purl.uniprot.org/uniprot/U5W5R8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1246995:AFR_RS36820 ^@ http://purl.uniprot.org/uniprot/U5WC68 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1246995:AFR_RS12025 ^@ http://purl.uniprot.org/uniprot/U5VUM4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1246995:AFR_RS23890 ^@ http://purl.uniprot.org/uniprot/U5W1W5 ^@ Similarity ^@ Belongs to the 4-hydroxy-2-oxovalerate aldolase family. http://togogenome.org/gene/1246995:AFR_RS16110 ^@ http://purl.uniprot.org/uniprot/U5VXG5 ^@ Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. http://togogenome.org/gene/1246995:AFR_RS07815 ^@ http://purl.uniprot.org/uniprot/U5VW01 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1246995:AFR_RS40690 ^@ http://purl.uniprot.org/uniprot/U5WBI2 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1246995:AFR_RS36230 ^@ http://purl.uniprot.org/uniprot/U5WBY3 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1246995:AFR_RS26975 ^@ http://purl.uniprot.org/uniprot/U5W6M8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1246995:AFR_RS04230 ^@ http://purl.uniprot.org/uniprot/U5VQQ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1246995:AFR_RS30695 ^@ http://purl.uniprot.org/uniprot/U5W5E5 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. http://togogenome.org/gene/1246995:AFR_RS35940 ^@ http://purl.uniprot.org/uniprot/U5W867 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/1246995:AFR_RS19825 ^@ http://purl.uniprot.org/uniprot/U5VZ05 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1246995:AFR_RS35160 ^@ http://purl.uniprot.org/uniprot/U5W8B9 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 65 family. http://togogenome.org/gene/1246995:AFR_RS43160 ^@ http://purl.uniprot.org/uniprot/U5WFM3 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1246995:AFR_RS24885 ^@ http://purl.uniprot.org/uniprot/U5W260 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family.