http://togogenome.org/gene/1222016:ELD05_RS08835 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6L1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1222016:ELD05_RS10945 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1222016:ELD05_RS13110 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8U5 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1222016:ELD05_RS06150 ^@ http://purl.uniprot.org/uniprot/A0A3T0D592 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS02620 ^@ http://purl.uniprot.org/uniprot/A0A3T0D410 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1222016:ELD05_RS07365 ^@ http://purl.uniprot.org/uniprot/A0A3T0D634 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1222016:ELD05_RS07180 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5W0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1222016:ELD05_RS03015 ^@ http://purl.uniprot.org/uniprot/A0A3T0D348 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1222016:ELD05_RS10400 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7D2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1222016:ELD05_RS05825 ^@ http://purl.uniprot.org/uniprot/A0A3T0D579 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1222016:ELD05_RS05365 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Z8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1222016:ELD05_RS04800 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4S6 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1222016:ELD05_RS05445 ^@ http://purl.uniprot.org/uniprot/A0A3T0D521 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1222016:ELD05_RS08465 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6H0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1222016:ELD05_RS00410 ^@ http://purl.uniprot.org/uniprot/A0A3T0D379 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1222016:ELD05_RS05040 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4T1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1222016:ELD05_RS05055 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4X4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1222016:ELD05_RS11190 ^@ http://purl.uniprot.org/uniprot/A0A3T0D869 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1222016:ELD05_RS04675 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N8 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1222016:ELD05_RS03265 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3S7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1222016:ELD05_RS08720 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6M9 ^@ Similarity ^@ Belongs to the HupF/HypC family. http://togogenome.org/gene/1222016:ELD05_RS08735 ^@ http://purl.uniprot.org/uniprot/A0A3T0D798 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1222016:ELD05_RS06355 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5I4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1222016:ELD05_RS04775 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Q4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL36 family. http://togogenome.org/gene/1222016:ELD05_RS05345 ^@ http://purl.uniprot.org/uniprot/A0A3T0D503 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/1222016:ELD05_RS05230 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Y0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1222016:ELD05_RS08600 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6J4 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1222016:ELD05_RS02990 ^@ http://purl.uniprot.org/uniprot/A0A3T0D361 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1222016:ELD05_RS03635 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3P4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1222016:ELD05_RS02285 ^@ http://purl.uniprot.org/uniprot/A0A3T0D403 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1222016:ELD05_RS13120 ^@ http://purl.uniprot.org/uniprot/A0A3T0D905 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-98 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/1222016:ELD05_RS11590 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS13875 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8W2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1222016:ELD05_RS03495 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3F2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Could methylate the ribose at the nucleotide 34 wobble position in tRNA.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1222016:ELD05_RS07710 ^@ http://purl.uniprot.org/uniprot/A0A3T0D633 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1222016:ELD05_RS03470 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3E5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1222016:ELD05_RS07645 ^@ http://purl.uniprot.org/uniprot/A0A3T0D642 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1222016:ELD05_RS06385 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5F5 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1222016:ELD05_RS05415 ^@ http://purl.uniprot.org/uniprot/A0A3T0D507 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS04795 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4R3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1222016:ELD05_RS00255 ^@ http://purl.uniprot.org/uniprot/A0A3T0D225 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1222016:ELD05_RS01590 ^@ http://purl.uniprot.org/uniprot/A0A3T0D304 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/1222016:ELD05_RS04650 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1222016:ELD05_RS04100 ^@ http://purl.uniprot.org/uniprot/A0A3T0D9F2 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1222016:ELD05_RS04665 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1222016:ELD05_RS05905 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5B5 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1222016:ELD05_RS05060 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4U2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1222016:ELD05_RS12920 ^@ http://purl.uniprot.org/uniprot/A0A3T0D938 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/1222016:ELD05_RS07430 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5Y5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1222016:ELD05_RS07265 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5V5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1222016:ELD05_RS03365 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3C4 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1222016:ELD05_RS04745 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Q3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1222016:ELD05_RS03290 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3Q4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1222016:ELD05_RS08760 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1222016:ELD05_RS07620 ^@ http://purl.uniprot.org/uniprot/A0A3T0D654 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1222016:ELD05_RS10310 ^@ http://purl.uniprot.org/uniprot/A0A3T0D865 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1222016:ELD05_RS04720 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4S4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1222016:ELD05_RS09155 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7G9 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1222016:ELD05_RS06170 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5C8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1222016:ELD05_RS02840 ^@ http://purl.uniprot.org/uniprot/A0A3T0D422 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/1222016:ELD05_RS10200 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/1222016:ELD05_RS06290 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5G9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1222016:ELD05_RS07205 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5U5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1222016:ELD05_RS09265 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6X8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1222016:ELD05_RS08370 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6F7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS08025 ^@ http://purl.uniprot.org/uniprot/A0A3T0D690 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/1222016:ELD05_RS04660 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1222016:ELD05_RS04770 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4T4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1222016:ELD05_RS10525 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7F3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1222016:ELD05_RS13105 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8T0 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/1222016:ELD05_RS10205 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7A5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1222016:ELD05_RS04655 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1222016:ELD05_RS06860 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5R4 ^@ Function|||Similarity|||Subunit ^@ Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.|||Belongs to the HutP family.|||Homohexamer. http://togogenome.org/gene/1222016:ELD05_RS04900 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4R1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1222016:ELD05_RS03550 ^@ http://purl.uniprot.org/uniprot/A0A3T0D478 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1222016:ELD05_RS00500 ^@ http://purl.uniprot.org/uniprot/A0A3T0D220 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1222016:ELD05_RS06360 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5D8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1222016:ELD05_RS12750 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1222016:ELD05_RS05005 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4S5 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1222016:ELD05_RS08585 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6W6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1222016:ELD05_RS06740 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5L0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1222016:ELD05_RS05425 ^@ http://purl.uniprot.org/uniprot/A0A3T0D504 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1222016:ELD05_RS06795 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5L2 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1222016:ELD05_RS07690 ^@ http://purl.uniprot.org/uniprot/A0A3T0D689 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1222016:ELD05_RS06295 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5G7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1222016:ELD05_RS06300 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5C7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1222016:ELD05_RS02430 ^@ http://purl.uniprot.org/uniprot/A0A3T0D2W4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1222016:ELD05_RS08755 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6L5 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/1222016:ELD05_RS03520 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3F9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1222016:ELD05_RS12515 ^@ http://purl.uniprot.org/uniprot/A0A3T0D999 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1222016:ELD05_RS02855 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3C3 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1222016:ELD05_RS04715 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1222016:ELD05_RS13115 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8J0 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1222016:ELD05_RS07570 ^@ http://purl.uniprot.org/uniprot/A0A3T0D617 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1222016:ELD05_RS05970 ^@ http://purl.uniprot.org/uniprot/A0A3T0D586 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1222016:ELD05_RS06390 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5F6 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1222016:ELD05_RS13835 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8V1 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1222016:ELD05_RS01135 ^@ http://purl.uniprot.org/uniprot/A0A3T0D2H5 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/1222016:ELD05_RS02975 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3Q3 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1222016:ELD05_RS08815 ^@ http://purl.uniprot.org/uniprot/A0A3T0D706 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS11555 ^@ http://purl.uniprot.org/uniprot/A0A3T0D841 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1222016:ELD05_RS09715 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7G2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1222016:ELD05_RS12780 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8D0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1222016:ELD05_RS05870 ^@ http://purl.uniprot.org/uniprot/A0A3T0D548 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1222016:ELD05_RS07605 ^@ http://purl.uniprot.org/uniprot/A0A3T0D615 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1222016:ELD05_RS04755 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4P5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1222016:ELD05_RS05280 ^@ http://purl.uniprot.org/uniprot/A0A3T0D584 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/1222016:ELD05_RS07135 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5T9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1222016:ELD05_RS10080 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7C3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1222016:ELD05_RS03690 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3Q0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1222016:ELD05_RS04780 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1222016:ELD05_RS09220 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6T2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS07390 ^@ http://purl.uniprot.org/uniprot/A0A3T0D624 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1222016:ELD05_RS07000 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5Q6 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1222016:ELD05_RS05050 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4U8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1222016:ELD05_RS06930 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5W3 ^@ Caution|||Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1222016:ELD05_RS05360 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8X6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1222016:ELD05_RS10940 ^@ http://purl.uniprot.org/uniprot/A0A3T0D807 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1222016:ELD05_RS08580 ^@ http://purl.uniprot.org/uniprot/A0A3T0D9E2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1222016:ELD05_RS04190 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4D8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1222016:ELD05_RS09910 ^@ http://purl.uniprot.org/uniprot/A0A3T0D731 ^@ Similarity ^@ Belongs to the GerABKA family. http://togogenome.org/gene/1222016:ELD05_RS05730 ^@ http://purl.uniprot.org/uniprot/A0A3T0D544 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1222016:ELD05_RS05930 ^@ http://purl.uniprot.org/uniprot/A0A3T0D599 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1222016:ELD05_RS02190 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3Y3 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1222016:ELD05_RS07610 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6J0 ^@ Similarity ^@ Belongs to the SleB family. http://togogenome.org/gene/1222016:ELD05_RS13125 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8J7 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1222016:ELD05_RS04725 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1222016:ELD05_RS06005 ^@ http://purl.uniprot.org/uniprot/A0A3T0D589 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1222016:ELD05_RS03035 ^@ http://purl.uniprot.org/uniprot/A0A3T0D363 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1222016:ELD05_RS02300 ^@ http://purl.uniprot.org/uniprot/A0A3T0D2U8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1222016:ELD05_RS06165 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1222016:ELD05_RS07560 ^@ http://purl.uniprot.org/uniprot/A0A3T0D646 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1222016:ELD05_RS04785 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1222016:ELD05_RS05065 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1222016:ELD05_RS04740 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1222016:ELD05_RS04730 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4P7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1222016:ELD05_RS13755 ^@ http://purl.uniprot.org/uniprot/A0A3T0D8T7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1222016:ELD05_RS04750 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1222016:ELD05_RS03140 ^@ http://purl.uniprot.org/uniprot/A0A3T0D370 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1222016:ELD05_RS05720 ^@ http://purl.uniprot.org/uniprot/A0A3T0D518 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1222016:ELD05_RS04705 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1222016:ELD05_RS09330 ^@ http://purl.uniprot.org/uniprot/A0A3T0D786 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/1222016:ELD05_RS05435 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4Y9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane|||This protein catalyzes the committed step to the synthesis of the acidic phospholipids. http://togogenome.org/gene/1222016:ELD05_RS04115 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4D6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/1222016:ELD05_RS11010 ^@ http://purl.uniprot.org/uniprot/A0A3T0D843 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1222016:ELD05_RS10120 ^@ http://purl.uniprot.org/uniprot/A0A3T0D7P2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1222016:ELD05_RS03580 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3N9 ^@ Similarity|||Subunit ^@ Belongs to the UPF0210 family.|||Homodimer. http://togogenome.org/gene/1222016:ELD05_RS04690 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1222016:ELD05_RS09985 ^@ http://purl.uniprot.org/uniprot/A0A3T0D791 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1222016:ELD05_RS06335 ^@ http://purl.uniprot.org/uniprot/A0A3T0D5F0 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1222016:ELD05_RS08595 ^@ http://purl.uniprot.org/uniprot/A0A3T0D9J2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1222016:ELD05_RS03585 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3V8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1222016:ELD05_RS03575 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3H0 ^@ Similarity ^@ Belongs to the UPF0237 family. http://togogenome.org/gene/1222016:ELD05_RS04645 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1222016:ELD05_RS04625 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4M8 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1222016:ELD05_RS10110 ^@ http://purl.uniprot.org/uniprot/A0A3T0D792 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1222016:ELD05_RS07460 ^@ http://purl.uniprot.org/uniprot/A0A3T0D669 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/1222016:ELD05_RS08610 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6K9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1222016:ELD05_RS08430 ^@ http://purl.uniprot.org/uniprot/A0A3T0D6H9 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/1222016:ELD05_RS09835 ^@ http://purl.uniprot.org/uniprot/A0A3T0D747 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1222016:ELD05_RS03830 ^@ http://purl.uniprot.org/uniprot/A0A3T0D486 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1222016:ELD05_RS02170 ^@ http://purl.uniprot.org/uniprot/A0A3T0D426 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1222016:ELD05_RS04500 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4J8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1222016:ELD05_RS00290 ^@ http://purl.uniprot.org/uniprot/A0A3T0D3P3 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated Csm2 family.|||This subunit may be involved in monitoring complementarity of crRNA and target RNA. http://togogenome.org/gene/1222016:ELD05_RS01350 ^@ http://purl.uniprot.org/uniprot/A0A3T0D2L1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1222016:ELD05_RS04760 ^@ http://purl.uniprot.org/uniprot/A0A3T0D4N9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.