http://togogenome.org/gene/1209989:TEPRE1_RS11745 ^@ http://purl.uniprot.org/uniprot/F4LT68 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lactate permease family.|||Cell membrane|||Membrane|||Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate. http://togogenome.org/gene/1209989:TEPRE1_RS04325 ^@ http://purl.uniprot.org/uniprot/F4LXD0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1209989:TEPRE1_RS11180 ^@ http://purl.uniprot.org/uniprot/F4LS26 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1209989:TEPRE1_RS11245 ^@ http://purl.uniprot.org/uniprot/F4LSI8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1209989:TEPRE1_RS06050 ^@ http://purl.uniprot.org/uniprot/F4LTM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1209989:TEPRE1_RS01550 ^@ http://purl.uniprot.org/uniprot/F4LTI1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1209989:TEPRE1_RS03000 ^@ http://purl.uniprot.org/uniprot/F4LVU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0316 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10160 ^@ http://purl.uniprot.org/uniprot/F4LR14 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS09530 ^@ http://purl.uniprot.org/uniprot/F4LQN8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1209989:TEPRE1_RS13000 ^@ http://purl.uniprot.org/uniprot/F4LV57 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS06090 ^@ http://purl.uniprot.org/uniprot/F4LTN6 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02320 ^@ http://purl.uniprot.org/uniprot/F4LUU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ALAD family.|||Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.|||Homooctamer. http://togogenome.org/gene/1209989:TEPRE1_RS07860 ^@ http://purl.uniprot.org/uniprot/F4LWB5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03350 ^@ http://purl.uniprot.org/uniprot/F4LW72 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1209989:TEPRE1_RS05950 ^@ http://purl.uniprot.org/uniprot/F4LTK8 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1209989:TEPRE1_RS01165 ^@ http://purl.uniprot.org/uniprot/F4LSY0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS00460 ^@ http://purl.uniprot.org/uniprot/F4LS41 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1209989:TEPRE1_RS01990 ^@ http://purl.uniprot.org/uniprot/F4LUM9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS01710 ^@ http://purl.uniprot.org/uniprot/F4LU18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS06185 ^@ http://purl.uniprot.org/uniprot/F4LTQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1209989:TEPRE1_RS02450 ^@ http://purl.uniprot.org/uniprot/F4LVB3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS00960 ^@ http://purl.uniprot.org/uniprot/F4LST9 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1209989:TEPRE1_RS10030 ^@ http://purl.uniprot.org/uniprot/F4LQY8 ^@ Similarity ^@ Belongs to the UPF0309 family. http://togogenome.org/gene/1209989:TEPRE1_RS00950 ^@ http://purl.uniprot.org/uniprot/F4LST7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1209989:TEPRE1_RS01030 ^@ http://purl.uniprot.org/uniprot/F4LSV3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS10335 ^@ http://purl.uniprot.org/uniprot/F4LR48 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1209989:TEPRE1_RS12790 ^@ http://purl.uniprot.org/uniprot/F4LUL5 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1209989:TEPRE1_RS01025 ^@ http://purl.uniprot.org/uniprot/F4LSV2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1209989:TEPRE1_RS08250 ^@ http://purl.uniprot.org/uniprot/F4LWR4 ^@ Function|||Similarity ^@ Belongs to the transposase 11 family.|||Involved in the transposition of the insertion sequence IS5. http://togogenome.org/gene/1209989:TEPRE1_RS08000 ^@ http://purl.uniprot.org/uniprot/F4LWE3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0291 family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS01750 ^@ http://purl.uniprot.org/uniprot/F4LU25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. C-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/1209989:TEPRE1_RS07840 ^@ http://purl.uniprot.org/uniprot/F4LWB1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS09705 ^@ http://purl.uniprot.org/uniprot/F4LQS3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS06985 ^@ http://purl.uniprot.org/uniprot/F4LV15 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1209989:TEPRE1_RS06010 ^@ http://purl.uniprot.org/uniprot/F4LTM0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.|||Cytoplasm|||Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity. http://togogenome.org/gene/1209989:TEPRE1_RS08740 ^@ http://purl.uniprot.org/uniprot/F4LX86 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS06100 ^@ http://purl.uniprot.org/uniprot/F4LTN8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS08355 ^@ http://purl.uniprot.org/uniprot/F4LWT5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06345 ^@ http://purl.uniprot.org/uniprot/F4LU87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS10880 ^@ http://purl.uniprot.org/uniprot/F4LRW4 ^@ Activity Regulation|||Function|||Similarity ^@ Appears to be allosterically activated by the binding of pArg-containing polypeptides to the pArg-binding pocket localized in the C-terminal domain of McsB.|||Belongs to the ATP:guanido phosphotransferase family.|||Catalyzes the specific phosphorylation of arginine residues in proteins. http://togogenome.org/gene/1209989:TEPRE1_RS07795 ^@ http://purl.uniprot.org/uniprot/F4LWA2 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/1209989:TEPRE1_RS13080 ^@ http://purl.uniprot.org/uniprot/F4LV70 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1209989:TEPRE1_RS13060 ^@ http://purl.uniprot.org/uniprot/F4LV66 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GdpP/PdeA phosphodiesterase family.|||Cell membrane|||For phosphodiesterase activity, probably binds 2 Mn(2+) per subunit.|||Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP). http://togogenome.org/gene/1209989:TEPRE1_RS05965 ^@ http://purl.uniprot.org/uniprot/F4LTL1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1209989:TEPRE1_RS07585 ^@ http://purl.uniprot.org/uniprot/F4LVZ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1209989:TEPRE1_RS00660 ^@ http://purl.uniprot.org/uniprot/F4LS78 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS07145 ^@ http://purl.uniprot.org/uniprot/F4LVI7 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1209989:TEPRE1_RS02530 ^@ http://purl.uniprot.org/uniprot/F4LVC8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10840 ^@ http://purl.uniprot.org/uniprot/F4LRF9 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1209989:TEPRE1_RS12365 ^@ http://purl.uniprot.org/uniprot/F4LTX9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10500 ^@ http://purl.uniprot.org/uniprot/F4LR98 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS09855 ^@ http://purl.uniprot.org/uniprot/F4LQV2 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS01740 ^@ http://purl.uniprot.org/uniprot/F4LU23 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1209989:TEPRE1_RS13150 ^@ http://purl.uniprot.org/uniprot/F4LV84 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1209989:TEPRE1_RS12390 ^@ http://purl.uniprot.org/uniprot/F4LTY4 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1209989:TEPRE1_RS09755 ^@ http://purl.uniprot.org/uniprot/F4LQT2 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04880 ^@ http://purl.uniprot.org/uniprot/F4LRR0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PstS family.|||Cell membrane|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Membrane|||Part of the ABC transporter complex PstSACB involved in phosphate import.|||The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS). http://togogenome.org/gene/1209989:TEPRE1_RS07150 ^@ http://purl.uniprot.org/uniprot/F4LVI8 ^@ Similarity ^@ Belongs to the UPF0473 family. http://togogenome.org/gene/1209989:TEPRE1_RS11225 ^@ http://purl.uniprot.org/uniprot/F4LS35 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS01630 ^@ http://purl.uniprot.org/uniprot/F4LU02 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS02515 ^@ http://purl.uniprot.org/uniprot/F4LVC5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07190 ^@ http://purl.uniprot.org/uniprot/F4LVJ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09485 ^@ http://purl.uniprot.org/uniprot/F4LQM9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05330 ^@ http://purl.uniprot.org/uniprot/F4LSF3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PurS family.|||Cytoplasm|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1209989:TEPRE1_RS06965 ^@ http://purl.uniprot.org/uniprot/F4LV11 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1209989:TEPRE1_RS02905 ^@ http://purl.uniprot.org/uniprot/F4LVS4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1209989:TEPRE1_RS07595 ^@ http://purl.uniprot.org/uniprot/F4LVZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1209989:TEPRE1_RS02170 ^@ http://purl.uniprot.org/uniprot/F4LUR4 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS06040 ^@ http://purl.uniprot.org/uniprot/F4LTM6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1209989:TEPRE1_RS06540 ^@ http://purl.uniprot.org/uniprot/F4LUC6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the OadG family.|||Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS06260 ^@ http://purl.uniprot.org/uniprot/F4LU70 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1209989:TEPRE1_RS10025 ^@ http://purl.uniprot.org/uniprot/F4LQY7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1209989:TEPRE1_RS01575 ^@ http://purl.uniprot.org/uniprot/F4LTI6 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS11120 ^@ http://purl.uniprot.org/uniprot/F4LS13 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/1209989:TEPRE1_RS06680 ^@ http://purl.uniprot.org/uniprot/F4LUV7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS04055 ^@ http://purl.uniprot.org/uniprot/F4LX06 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS02825 ^@ http://purl.uniprot.org/uniprot/F4LVQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1209989:TEPRE1_RS10905 ^@ http://purl.uniprot.org/uniprot/F4LRW9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1209989:TEPRE1_RS06265 ^@ http://purl.uniprot.org/uniprot/F4LU71 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS01045 ^@ http://purl.uniprot.org/uniprot/F4LSV6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1209989:TEPRE1_RS11110 ^@ http://purl.uniprot.org/uniprot/F4LS11 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS01090 ^@ http://purl.uniprot.org/uniprot/F4LSW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC transporter superfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07800 ^@ http://purl.uniprot.org/uniprot/F4LWA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01765 ^@ http://purl.uniprot.org/uniprot/F4LU28 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1209989:TEPRE1_RS04830 ^@ http://purl.uniprot.org/uniprot/F4LRQ0 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1209989:TEPRE1_RS10760 ^@ http://purl.uniprot.org/uniprot/F4LRE7 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1209989:TEPRE1_RS06600 ^@ http://purl.uniprot.org/uniprot/F4LUD8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS02140 ^@ http://purl.uniprot.org/uniprot/F4LUQ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/1209989:TEPRE1_RS01745 ^@ http://purl.uniprot.org/uniprot/F4LU24 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family. N-terminal subunit subfamily.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits. http://togogenome.org/gene/1209989:TEPRE1_RS09350 ^@ http://purl.uniprot.org/uniprot/F4LQK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00650 ^@ http://purl.uniprot.org/uniprot/F4LS76 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1209989:TEPRE1_RS06340 ^@ http://purl.uniprot.org/uniprot/F4LU86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1209989:TEPRE1_RS04165 ^@ http://purl.uniprot.org/uniprot/F4LX26 ^@ Similarity ^@ Belongs to the FlgM family. http://togogenome.org/gene/1209989:TEPRE1_RS00455 ^@ http://purl.uniprot.org/uniprot/F4LS40 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1209989:TEPRE1_RS09120 ^@ http://purl.uniprot.org/uniprot/F4LXN1 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08980 ^@ http://purl.uniprot.org/uniprot/F4LXK3 ^@ Activity Regulation|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1209989:TEPRE1_RS02240 ^@ http://purl.uniprot.org/uniprot/F4LUS8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10145 ^@ http://purl.uniprot.org/uniprot/L0S592 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06155 ^@ http://purl.uniprot.org/uniprot/F4LTP9 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04470 ^@ http://purl.uniprot.org/uniprot/F4LXG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05670 ^@ http://purl.uniprot.org/uniprot/F4LT18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS03520 ^@ http://purl.uniprot.org/uniprot/F4LWH5 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport: it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion.|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1209989:TEPRE1_RS00830 ^@ http://purl.uniprot.org/uniprot/F4LSR3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1209989:TEPRE1_RS01470 ^@ http://purl.uniprot.org/uniprot/F4LTG5 ^@ Subcellular Location Annotation ^@ Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS06045 ^@ http://purl.uniprot.org/uniprot/F4LTM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS07870 ^@ http://purl.uniprot.org/uniprot/F4LWB7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04950 ^@ http://purl.uniprot.org/uniprot/F4LRS4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07315 ^@ http://purl.uniprot.org/uniprot/F4LVM1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS06510 ^@ http://purl.uniprot.org/uniprot/F4LUC0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1209989:TEPRE1_RS10535 ^@ http://purl.uniprot.org/uniprot/F4LRA5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS11205 ^@ http://purl.uniprot.org/uniprot/F4LS31 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS00680 ^@ http://purl.uniprot.org/uniprot/F4LS82 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09135 ^@ http://purl.uniprot.org/uniprot/F4LXN4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS01055 ^@ http://purl.uniprot.org/uniprot/F4LSV8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1209989:TEPRE1_RS01005 ^@ http://purl.uniprot.org/uniprot/F4LSU8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1209989:TEPRE1_RS02060 ^@ http://purl.uniprot.org/uniprot/F4LUP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12950 ^@ http://purl.uniprot.org/uniprot/F4LV47 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/1209989:TEPRE1_RS11370 ^@ http://purl.uniprot.org/uniprot/F4LSL1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS02380 ^@ http://purl.uniprot.org/uniprot/F4LV99 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05480 ^@ http://purl.uniprot.org/uniprot/F4LSI3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1209989:TEPRE1_RS00465 ^@ http://purl.uniprot.org/uniprot/F4LS42 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1209989:TEPRE1_RS03020 ^@ http://purl.uniprot.org/uniprot/F4LVU4 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1209989:TEPRE1_RS05595 ^@ http://purl.uniprot.org/uniprot/F4LT03 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1209989:TEPRE1_RS00930 ^@ http://purl.uniprot.org/uniprot/F4LRF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1209989:TEPRE1_RS03860 ^@ http://purl.uniprot.org/uniprot/F4LWP2 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS03955 ^@ http://purl.uniprot.org/uniprot/F4LWY6 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1209989:TEPRE1_RS01975 ^@ http://purl.uniprot.org/uniprot/F4LUM6 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1209989:TEPRE1_RS05005 ^@ http://purl.uniprot.org/uniprot/F4LRT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobS family.|||Cell membrane|||Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01135 ^@ http://purl.uniprot.org/uniprot/F4LSX4 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1209989:TEPRE1_RS04890 ^@ http://purl.uniprot.org/uniprot/F4LRR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01105 ^@ http://purl.uniprot.org/uniprot/F4LSW8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10770 ^@ http://purl.uniprot.org/uniprot/F4LRE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1209989:TEPRE1_RS01325 ^@ http://purl.uniprot.org/uniprot/F4LTD9 ^@ Similarity ^@ Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS03460 ^@ http://purl.uniprot.org/uniprot/F4LW88 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1209989:TEPRE1_RS01370 ^@ http://purl.uniprot.org/uniprot/F4LTE6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS00425 ^@ http://purl.uniprot.org/uniprot/F4LRN4 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1209989:TEPRE1_RS07355 ^@ http://purl.uniprot.org/uniprot/F4LVM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1209989:TEPRE1_RS00920 ^@ http://purl.uniprot.org/uniprot/F4LST1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1209989:TEPRE1_RS00990 ^@ http://purl.uniprot.org/uniprot/F4LSU5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1209989:TEPRE1_RS01080 ^@ http://purl.uniprot.org/uniprot/F4LSW3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1209989:TEPRE1_RS04815 ^@ http://purl.uniprot.org/uniprot/F4LRP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. OAT subfamily.|||Catalyzes the interconversion of ornithine to glutamate semialdehyde.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS11705 ^@ http://purl.uniprot.org/uniprot/F4LT60 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03685 ^@ http://purl.uniprot.org/uniprot/F4LWK8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07525 ^@ http://purl.uniprot.org/uniprot/F4LVY0 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06585 ^@ http://purl.uniprot.org/uniprot/F4LUD5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS01110 ^@ http://purl.uniprot.org/uniprot/F4LSW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1209989:TEPRE1_RS05570 ^@ http://purl.uniprot.org/uniprot/F4LSZ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1209989:TEPRE1_RS08255 ^@ http://purl.uniprot.org/uniprot/F4LWR5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1209989:TEPRE1_RS03305 ^@ http://purl.uniprot.org/uniprot/F4LW64 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1209989:TEPRE1_RS09100 ^@ http://purl.uniprot.org/uniprot/F4LXM7 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1209989:TEPRE1_RS00500 ^@ http://purl.uniprot.org/uniprot/F4LS49 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1209989:TEPRE1_RS03900 ^@ http://purl.uniprot.org/uniprot/F4LWX5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS12780 ^@ http://purl.uniprot.org/uniprot/F4LUL3 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1209989:TEPRE1_RS14070 ^@ http://purl.uniprot.org/uniprot/F4LQV0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS08105 ^@ http://purl.uniprot.org/uniprot/F4LWG2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS03960 ^@ http://purl.uniprot.org/uniprot/F4LWY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07165 ^@ http://purl.uniprot.org/uniprot/F4LVJ1 ^@ Similarity ^@ Belongs to the UPF0297 family. http://togogenome.org/gene/1209989:TEPRE1_RS00270 ^@ http://purl.uniprot.org/uniprot/F4LRK4 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1209989:TEPRE1_RS12595 ^@ http://purl.uniprot.org/uniprot/F4LUH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1209989:TEPRE1_RS01215 ^@ http://purl.uniprot.org/uniprot/F4LTB8 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS08280 ^@ http://purl.uniprot.org/uniprot/F4LWS0 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1209989:TEPRE1_RS00800 ^@ http://purl.uniprot.org/uniprot/F4LSA7 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1209989:TEPRE1_RS12760 ^@ http://purl.uniprot.org/uniprot/F4LUK9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS06445 ^@ http://purl.uniprot.org/uniprot/F4LUA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS12725 ^@ http://purl.uniprot.org/uniprot/F4LUK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00010 ^@ http://purl.uniprot.org/uniprot/F4LR74 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1209989:TEPRE1_RS08745 ^@ http://purl.uniprot.org/uniprot/F4LX87 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS11675 ^@ http://purl.uniprot.org/uniprot/F4LT54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12720 ^@ http://purl.uniprot.org/uniprot/F4LUK0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09885 ^@ http://purl.uniprot.org/uniprot/F4LQV8 ^@ Function|||Similarity ^@ Belongs to the aspartokinase family.|||Catalyzes the phosphorylation of the beta-carboxyl group of aspartic acid with ATP to yield 4-phospho-L-aspartate, which is involved in the branched biosynthetic pathway leading to the biosynthesis of amino acids threonine, isoleucine and methionine. http://togogenome.org/gene/1209989:TEPRE1_RS03705 ^@ http://purl.uniprot.org/uniprot/F4LWL2 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1209989:TEPRE1_RS00045 ^@ http://purl.uniprot.org/uniprot/F4LRG1 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/1209989:TEPRE1_RS10175 ^@ http://purl.uniprot.org/uniprot/F4LR17 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS01100 ^@ http://purl.uniprot.org/uniprot/F4LSW7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the energy-coupling factor EcfT family.|||Cell membrane|||Forms a stable energy-coupling factor (ECF) transporter complex composed of 2 membrane-embedded substrate-binding proteins (S component), 2 ATP-binding proteins (A component) and 2 transmembrane proteins (T component).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. http://togogenome.org/gene/1209989:TEPRE1_RS02415 ^@ http://purl.uniprot.org/uniprot/F4LVA6 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1209989:TEPRE1_RS10355 ^@ http://purl.uniprot.org/uniprot/F4LR52 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS07780 ^@ http://purl.uniprot.org/uniprot/F4LW29 ^@ Similarity ^@ Belongs to the four-carbon acid sugar kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS07415 ^@ http://purl.uniprot.org/uniprot/F4LVV9 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS02210 ^@ http://purl.uniprot.org/uniprot/F4LUS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08175 ^@ http://purl.uniprot.org/uniprot/F4LWQ3 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS08615 ^@ http://purl.uniprot.org/uniprot/F4LX61 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10835 ^@ http://purl.uniprot.org/uniprot/F4LRF8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS09380 ^@ http://purl.uniprot.org/uniprot/F4LQK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS09850 ^@ http://purl.uniprot.org/uniprot/F4LQV1 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS07390 ^@ http://purl.uniprot.org/uniprot/F4LVN6 ^@ Function|||Similarity|||Subunit ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Homodimer and homohexamer; in equilibrium.|||Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes. http://togogenome.org/gene/1209989:TEPRE1_RS05775 ^@ http://purl.uniprot.org/uniprot/F4LT39 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1209989:TEPRE1_RS07705 ^@ http://purl.uniprot.org/uniprot/F4LW18 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1209989:TEPRE1_RS07330 ^@ http://purl.uniprot.org/uniprot/F4LVM4 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1209989:TEPRE1_RS09230 ^@ http://purl.uniprot.org/uniprot/F4LXQ2 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1209989:TEPRE1_RS00230 ^@ http://purl.uniprot.org/uniprot/F4LRJ7 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS03135 ^@ http://purl.uniprot.org/uniprot/F4LW31 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS05580 ^@ http://purl.uniprot.org/uniprot/F4LT00 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1209989:TEPRE1_RS03065 ^@ http://purl.uniprot.org/uniprot/F4LVU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1209989:TEPRE1_RS10955 ^@ http://purl.uniprot.org/uniprot/F4LRX9 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1209989:TEPRE1_RS06755 ^@ http://purl.uniprot.org/uniprot/F4LUW8 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS06430 ^@ http://purl.uniprot.org/uniprot/F4LUA4 ^@ Similarity ^@ Belongs to the AAA ATPase family.|||In the C-terminal section; belongs to the peptidase M41 family. http://togogenome.org/gene/1209989:TEPRE1_RS04395 ^@ http://purl.uniprot.org/uniprot/F4LXE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03295 ^@ http://purl.uniprot.org/uniprot/F4LW63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06550 ^@ http://purl.uniprot.org/uniprot/F4LUC8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01895 ^@ http://purl.uniprot.org/uniprot/F4LU52 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1209989:TEPRE1_RS06385 ^@ http://purl.uniprot.org/uniprot/F4LU95 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1209989:TEPRE1_RS07005 ^@ http://purl.uniprot.org/uniprot/F4LV19 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1209989:TEPRE1_RS11105 ^@ http://purl.uniprot.org/uniprot/F4LS10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetokinase family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS07900 ^@ http://purl.uniprot.org/uniprot/F4LWC3 ^@ Function|||Similarity ^@ Belongs to the UxaE family.|||Catalyzes the epimerization of D-tagaturonate (D-TagA) to D-fructuronate (D-FruA). http://togogenome.org/gene/1209989:TEPRE1_RS08425 ^@ http://purl.uniprot.org/uniprot/F4LWU9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS02765 ^@ http://purl.uniprot.org/uniprot/F4LVP6 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1209989:TEPRE1_RS00900 ^@ http://purl.uniprot.org/uniprot/F4LSS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1209989:TEPRE1_RS12270 ^@ http://purl.uniprot.org/uniprot/F4LTW1 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS05855 ^@ http://purl.uniprot.org/uniprot/F4LT49 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1209989:TEPRE1_RS13915 ^@ http://purl.uniprot.org/uniprot/L0S205 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CotF family.|||Spore coat http://togogenome.org/gene/1209989:TEPRE1_RS00525 ^@ http://purl.uniprot.org/uniprot/F4LS54 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas6/Cse3/CasE family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1209989:TEPRE1_RS07185 ^@ http://purl.uniprot.org/uniprot/F4LVJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS01935 ^@ http://purl.uniprot.org/uniprot/F4LU60 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1209989:TEPRE1_RS02595 ^@ http://purl.uniprot.org/uniprot/F4LVE1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05730 ^@ http://purl.uniprot.org/uniprot/F4LT30 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1209989:TEPRE1_RS08235 ^@ http://purl.uniprot.org/uniprot/F4LWR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07155 ^@ http://purl.uniprot.org/uniprot/F4LVI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS12840 ^@ http://purl.uniprot.org/uniprot/F4LV23 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1209989:TEPRE1_RS00765 ^@ http://purl.uniprot.org/uniprot/F4LSA0 ^@ Function|||Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family.|||This protein is a Fe-Mo-cofactor biosynthetic component. http://togogenome.org/gene/1209989:TEPRE1_RS05425 ^@ http://purl.uniprot.org/uniprot/F4LSH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1209989:TEPRE1_RS09455 ^@ http://purl.uniprot.org/uniprot/F4LQM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1209989:TEPRE1_RS03765 ^@ http://purl.uniprot.org/uniprot/F4LWM4 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1209989:TEPRE1_RS04175 ^@ http://purl.uniprot.org/uniprot/F4LX28 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1209989:TEPRE1_RS10765 ^@ http://purl.uniprot.org/uniprot/F4LRE8 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1209989:TEPRE1_RS05435 ^@ http://purl.uniprot.org/uniprot/F4LSH4 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1209989:TEPRE1_RS10875 ^@ http://purl.uniprot.org/uniprot/F4LRW3 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1209989:TEPRE1_RS01640 ^@ http://purl.uniprot.org/uniprot/F4LU04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06685 ^@ http://purl.uniprot.org/uniprot/F4LUV8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS08150 ^@ http://purl.uniprot.org/uniprot/F4LWH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04190 ^@ http://purl.uniprot.org/uniprot/F4LX31 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/1209989:TEPRE1_RS09600 ^@ http://purl.uniprot.org/uniprot/F4LQQ2 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS03575 ^@ http://purl.uniprot.org/uniprot/F4LWI6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11055 ^@ http://purl.uniprot.org/uniprot/F4LS00 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS04525 ^@ http://purl.uniprot.org/uniprot/F4LXG9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS06945 ^@ http://purl.uniprot.org/uniprot/F4LV07 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1209989:TEPRE1_RS12825 ^@ http://purl.uniprot.org/uniprot/F4LUM2 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1209989:TEPRE1_RS08220 ^@ http://purl.uniprot.org/uniprot/F4LWR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06270 ^@ http://purl.uniprot.org/uniprot/F4LU72 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS03130 ^@ http://purl.uniprot.org/uniprot/F4LW30 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10210 ^@ http://purl.uniprot.org/uniprot/F4LR24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS01455 ^@ http://purl.uniprot.org/uniprot/F4LTG2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10005 ^@ http://purl.uniprot.org/uniprot/F4LQY3 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1209989:TEPRE1_RS12305 ^@ http://purl.uniprot.org/uniprot/F4LTW8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/1209989:TEPRE1_RS09965 ^@ http://purl.uniprot.org/uniprot/F4LQX4 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1209989:TEPRE1_RS06580 ^@ http://purl.uniprot.org/uniprot/F4LUD4 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1209989:TEPRE1_RS06080 ^@ http://purl.uniprot.org/uniprot/F4LTN4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1209989:TEPRE1_RS08715 ^@ http://purl.uniprot.org/uniprot/F4LX82 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00965 ^@ http://purl.uniprot.org/uniprot/F4LSU0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1209989:TEPRE1_RS00755 ^@ http://purl.uniprot.org/uniprot/F4LS98 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07555 ^@ http://purl.uniprot.org/uniprot/F4LVY7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1209989:TEPRE1_RS03345 ^@ http://purl.uniprot.org/uniprot/F4LW71 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.|||This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one. http://togogenome.org/gene/1209989:TEPRE1_RS09395 ^@ http://purl.uniprot.org/uniprot/F4LQL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrB/RnfD family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS07170 ^@ http://purl.uniprot.org/uniprot/F4LVJ2 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS10870 ^@ http://purl.uniprot.org/uniprot/F4LRW2 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1209989:TEPRE1_RS07400 ^@ http://purl.uniprot.org/uniprot/F4LVN8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1209989:TEPRE1_RS10640 ^@ http://purl.uniprot.org/uniprot/F4LRC6 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS02345 ^@ http://purl.uniprot.org/uniprot/F4LUU9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1209989:TEPRE1_RS10520 ^@ http://purl.uniprot.org/uniprot/F4LRA2 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1209989:TEPRE1_RS09490 ^@ http://purl.uniprot.org/uniprot/F4LQN0 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1209989:TEPRE1_RS10900 ^@ http://purl.uniprot.org/uniprot/F4LRW8 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS06255 ^@ http://purl.uniprot.org/uniprot/F4LU69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09660 ^@ http://purl.uniprot.org/uniprot/F4LQR4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1209989:TEPRE1_RS11255 ^@ http://purl.uniprot.org/uniprot/F4LSJ0 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS00205 ^@ http://purl.uniprot.org/uniprot/F4LRJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01965 ^@ http://purl.uniprot.org/uniprot/F4LU66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1209989:TEPRE1_RS07450 ^@ http://purl.uniprot.org/uniprot/F4LVW5 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1209989:TEPRE1_RS06005 ^@ http://purl.uniprot.org/uniprot/F4LTL9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1209989:TEPRE1_RS01725 ^@ http://purl.uniprot.org/uniprot/F4LU20 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS02550 ^@ http://purl.uniprot.org/uniprot/F4LVD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00735 ^@ http://purl.uniprot.org/uniprot/F4LS94 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1209989:TEPRE1_RS11415 ^@ http://purl.uniprot.org/uniprot/F4LSM0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1209989:TEPRE1_RS03590 ^@ http://purl.uniprot.org/uniprot/F4LWI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/1209989:TEPRE1_RS11805 ^@ http://purl.uniprot.org/uniprot/F4LT80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07695 ^@ http://purl.uniprot.org/uniprot/F4LW16 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS03475 ^@ http://purl.uniprot.org/uniprot/F4LW91 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Nucleus|||Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. http://togogenome.org/gene/1209989:TEPRE1_RS07570 ^@ http://purl.uniprot.org/uniprot/F4LVZ0 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1209989:TEPRE1_RS10135 ^@ http://purl.uniprot.org/uniprot/F4LR09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12515 ^@ http://purl.uniprot.org/uniprot/F4LUG0 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS10245 ^@ http://purl.uniprot.org/uniprot/F4LR31 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1209989:TEPRE1_RS08375 ^@ http://purl.uniprot.org/uniprot/F4LWT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09760 ^@ http://purl.uniprot.org/uniprot/F4LQT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02195 ^@ http://purl.uniprot.org/uniprot/F4LUR9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1209989:TEPRE1_RS10570 ^@ http://purl.uniprot.org/uniprot/F4LRB2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03375 ^@ http://purl.uniprot.org/uniprot/F4LW77 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1209989:TEPRE1_RS05180 ^@ http://purl.uniprot.org/uniprot/F4LSC5 ^@ Similarity ^@ Belongs to the HicA mRNA interferase family. http://togogenome.org/gene/1209989:TEPRE1_RS11985 ^@ http://purl.uniprot.org/uniprot/F4LTA2 ^@ Similarity ^@ Belongs to the Rpn/YhgA-like nuclease family. http://togogenome.org/gene/1209989:TEPRE1_RS05985 ^@ http://purl.uniprot.org/uniprot/F4LTL5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1209989:TEPRE1_RS08625 ^@ http://purl.uniprot.org/uniprot/F4LX63 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS11020 ^@ http://purl.uniprot.org/uniprot/F4LRZ3 ^@ Similarity ^@ Belongs to the RuBisCO large chain family. http://togogenome.org/gene/1209989:TEPRE1_RS12600 ^@ http://purl.uniprot.org/uniprot/F4LUH7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02970 ^@ http://purl.uniprot.org/uniprot/F4LVT4 ^@ Caution|||Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS09300 ^@ http://purl.uniprot.org/uniprot/F4LXR5 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1209989:TEPRE1_RS05390 ^@ http://purl.uniprot.org/uniprot/F4LSG5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08910 ^@ http://purl.uniprot.org/uniprot/F4LXB9 ^@ Function|||Similarity ^@ Belongs to the methylglyoxal synthase family.|||Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS00675 ^@ http://purl.uniprot.org/uniprot/F4LS81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07250 ^@ http://purl.uniprot.org/uniprot/F4LVK8 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS06935 ^@ http://purl.uniprot.org/uniprot/F4LV05 ^@ Cofactor|||Function|||Subcellular Location Annotation ^@ Binds 1 Ca(2+) ion per subunit.|||Cytoplasm|||May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS04140 ^@ http://purl.uniprot.org/uniprot/F4LX21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1209989:TEPRE1_RS07575 ^@ http://purl.uniprot.org/uniprot/F4LVZ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS00225 ^@ http://purl.uniprot.org/uniprot/F4LRJ6 ^@ Similarity ^@ Belongs to the organic radical-activating enzymes family. http://togogenome.org/gene/1209989:TEPRE1_RS09540 ^@ http://purl.uniprot.org/uniprot/F4LQP0 ^@ Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family. http://togogenome.org/gene/1209989:TEPRE1_RS07385 ^@ http://purl.uniprot.org/uniprot/F4LVN5 ^@ Function|||Similarity|||Subunit ^@ Associates with stalled 50S ribosomal subunits.|||Belongs to the NEMF family.|||Part of the ribosome quality control system (RQC). Recruits Ala-charged tRNA and directs the elongation of stalled nascent chains on 50S ribosomal subunits, leading to non-templated C-terminal Ala extensions (Ala tail). The Ala tail promotes nascent chain degradation. May add between 1 and at least 8 Ala residues. Binds to stalled 50S ribosomal subunits. http://togogenome.org/gene/1209989:TEPRE1_RS10845 ^@ http://purl.uniprot.org/uniprot/F4LRG0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS06975 ^@ http://purl.uniprot.org/uniprot/F4LV13 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1209989:TEPRE1_RS04355 ^@ http://purl.uniprot.org/uniprot/F4LXD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05645 ^@ http://purl.uniprot.org/uniprot/F4LT13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1209989:TEPRE1_RS05925 ^@ http://purl.uniprot.org/uniprot/F4LTK3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1209989:TEPRE1_RS05600 ^@ http://purl.uniprot.org/uniprot/F4LT04 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1209989:TEPRE1_RS08530 ^@ http://purl.uniprot.org/uniprot/F4LWX0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the FBP aldolase/phosphatase family.|||Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).|||Consists of a single catalytic domain, but remodels its active-site architecture via a large structural change to exhibit dual activities.|||Homooctamer; dimer of tetramers. http://togogenome.org/gene/1209989:TEPRE1_RS12350 ^@ http://purl.uniprot.org/uniprot/F4LTX6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS08200 ^@ http://purl.uniprot.org/uniprot/F4LWQ7 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS10165 ^@ http://purl.uniprot.org/uniprot/F4LR15 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09370 ^@ http://purl.uniprot.org/uniprot/F4LQK6 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/1209989:TEPRE1_RS09605 ^@ http://purl.uniprot.org/uniprot/F4LQQ3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS12255 ^@ http://purl.uniprot.org/uniprot/L0S2W1 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1209989:TEPRE1_RS06605 ^@ http://purl.uniprot.org/uniprot/F4LUD9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Hfq family.|||Homohexamer.|||RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. http://togogenome.org/gene/1209989:TEPRE1_RS11380 ^@ http://purl.uniprot.org/uniprot/F4LSL3 ^@ Function ^@ Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase. http://togogenome.org/gene/1209989:TEPRE1_RS08870 ^@ http://purl.uniprot.org/uniprot/F4LXB0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03220 ^@ http://purl.uniprot.org/uniprot/F4LW48 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS05900 ^@ http://purl.uniprot.org/uniprot/F4LTJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1209989:TEPRE1_RS05700 ^@ http://purl.uniprot.org/uniprot/F4LT24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1209989:TEPRE1_RS02235 ^@ http://purl.uniprot.org/uniprot/F4LUS7 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1209989:TEPRE1_RS04035 ^@ http://purl.uniprot.org/uniprot/F4LX02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11395 ^@ http://purl.uniprot.org/uniprot/F4LSL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06140 ^@ http://purl.uniprot.org/uniprot/F4LTP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02545 ^@ http://purl.uniprot.org/uniprot/F4LVD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00020 ^@ http://purl.uniprot.org/uniprot/F4LR76 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1209989:TEPRE1_RS03790 ^@ http://purl.uniprot.org/uniprot/F4LWM9 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1209989:TEPRE1_RS12355 ^@ http://purl.uniprot.org/uniprot/F4LTX7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1209989:TEPRE1_RS08515 ^@ http://purl.uniprot.org/uniprot/F4LWW7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1209989:TEPRE1_RS03355 ^@ http://purl.uniprot.org/uniprot/F4LW73 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS05385 ^@ http://purl.uniprot.org/uniprot/F4LSG4 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1209989:TEPRE1_RS13190 ^@ http://purl.uniprot.org/uniprot/F4LV92 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1209989:TEPRE1_RS01530 ^@ http://purl.uniprot.org/uniprot/K7SGY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS04840 ^@ http://purl.uniprot.org/uniprot/F4LRQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0702 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12470 ^@ http://purl.uniprot.org/uniprot/F4LUF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06150 ^@ http://purl.uniprot.org/uniprot/F4LTP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06760 ^@ http://purl.uniprot.org/uniprot/F4LUW9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS12315 ^@ http://purl.uniprot.org/uniprot/F4LTX0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1209989:TEPRE1_RS02205 ^@ http://purl.uniprot.org/uniprot/F4LUS1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12085 ^@ http://purl.uniprot.org/uniprot/F4LTS7 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/1209989:TEPRE1_RS11060 ^@ http://purl.uniprot.org/uniprot/F4LS01 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1209989:TEPRE1_RS10615 ^@ http://purl.uniprot.org/uniprot/F4LRC1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1209989:TEPRE1_RS02180 ^@ http://purl.uniprot.org/uniprot/F4LUR6 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS01010 ^@ http://purl.uniprot.org/uniprot/F4LSU9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1209989:TEPRE1_RS06980 ^@ http://purl.uniprot.org/uniprot/F4LV14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1209989:TEPRE1_RS00440 ^@ http://purl.uniprot.org/uniprot/F4LS37 ^@ Similarity ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS01545 ^@ http://purl.uniprot.org/uniprot/F4LTI0 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1209989:TEPRE1_RS11610 ^@ http://purl.uniprot.org/uniprot/F4LSQ7 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1209989:TEPRE1_RS05845 ^@ http://purl.uniprot.org/uniprot/F4LT47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS08565 ^@ http://purl.uniprot.org/uniprot/F4LX51 ^@ Caution|||Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS02540 ^@ http://purl.uniprot.org/uniprot/F4LVD0 ^@ Similarity ^@ Belongs to the V-ATPase V0D/AC39 subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS11030 ^@ http://purl.uniprot.org/uniprot/F4LRZ5 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS06120 ^@ http://purl.uniprot.org/uniprot/F4LTP2 ^@ Similarity ^@ Belongs to the FlgD family. http://togogenome.org/gene/1209989:TEPRE1_RS10750 ^@ http://purl.uniprot.org/uniprot/F4LRE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1209989:TEPRE1_RS03820 ^@ http://purl.uniprot.org/uniprot/F4LWN5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1209989:TEPRE1_RS08260 ^@ http://purl.uniprot.org/uniprot/F4LWR6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1209989:TEPRE1_RS04315 ^@ http://purl.uniprot.org/uniprot/F4LXC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1209989:TEPRE1_RS09860 ^@ http://purl.uniprot.org/uniprot/F4LQV3 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/1209989:TEPRE1_RS07430 ^@ http://purl.uniprot.org/uniprot/F4LVW2 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1209989:TEPRE1_RS10595 ^@ http://purl.uniprot.org/uniprot/F4LRB7 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1209989:TEPRE1_RS08935 ^@ http://purl.uniprot.org/uniprot/F4LXJ4 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/1209989:TEPRE1_RS02485 ^@ http://purl.uniprot.org/uniprot/F4LVC0 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1209989:TEPRE1_RS12395 ^@ http://purl.uniprot.org/uniprot/F4LTY5 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-I family. http://togogenome.org/gene/1209989:TEPRE1_RS01040 ^@ http://purl.uniprot.org/uniprot/F4LSV5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS00980 ^@ http://purl.uniprot.org/uniprot/F4LSU3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1209989:TEPRE1_RS00275 ^@ http://purl.uniprot.org/uniprot/F4LRK5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03600 ^@ http://purl.uniprot.org/uniprot/F4LWJ1 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain. http://togogenome.org/gene/1209989:TEPRE1_RS01160 ^@ http://purl.uniprot.org/uniprot/F4LSX9 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1209989:TEPRE1_RS02125 ^@ http://purl.uniprot.org/uniprot/F4LUQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10425 ^@ http://purl.uniprot.org/uniprot/F4LR66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07885 ^@ http://purl.uniprot.org/uniprot/F4LWC0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00105 ^@ http://purl.uniprot.org/uniprot/F4LRH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS11735 ^@ http://purl.uniprot.org/uniprot/F4LT66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/1209989:TEPRE1_RS09555 ^@ http://purl.uniprot.org/uniprot/F4LQP3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS08730 ^@ http://purl.uniprot.org/uniprot/F4LX84 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS09030 ^@ http://purl.uniprot.org/uniprot/F4LXL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05970 ^@ http://purl.uniprot.org/uniprot/F4LTL2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1209989:TEPRE1_RS09950 ^@ http://purl.uniprot.org/uniprot/F4LQX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06590 ^@ http://purl.uniprot.org/uniprot/F4LUD6 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1209989:TEPRE1_RS04620 ^@ http://purl.uniprot.org/uniprot/F4LXI7 ^@ Function|||Similarity ^@ Belongs to the transposase mutator family.|||Required for the transposition of the insertion element. http://togogenome.org/gene/1209989:TEPRE1_RS12625 ^@ http://purl.uniprot.org/uniprot/F4LUI1 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS07700 ^@ http://purl.uniprot.org/uniprot/F4LW17 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1209989:TEPRE1_RS09920 ^@ http://purl.uniprot.org/uniprot/F4LQW5 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS09645 ^@ http://purl.uniprot.org/uniprot/F4LQR1 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS10295 ^@ http://purl.uniprot.org/uniprot/F4LR40 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1209989:TEPRE1_RS09890 ^@ http://purl.uniprot.org/uniprot/F4LQV9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS02555 ^@ http://purl.uniprot.org/uniprot/F4LVD3 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS13330 ^@ http://purl.uniprot.org/uniprot/F4LRX8 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1209989:TEPRE1_RS12005 ^@ http://purl.uniprot.org/uniprot/F4LTA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00570 ^@ http://purl.uniprot.org/uniprot/F4LS62 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmE subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10940 ^@ http://purl.uniprot.org/uniprot/F4LRX6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit.|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS09680 ^@ http://purl.uniprot.org/uniprot/F4LQR8 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS01350 ^@ http://purl.uniprot.org/uniprot/F4LTE2 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1209989:TEPRE1_RS00265 ^@ http://purl.uniprot.org/uniprot/F4LRK3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1209989:TEPRE1_RS02265 ^@ http://purl.uniprot.org/uniprot/F4LUT3 ^@ Function|||Similarity ^@ Belongs to the CbiD family.|||Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. http://togogenome.org/gene/1209989:TEPRE1_RS08080 ^@ http://purl.uniprot.org/uniprot/F4LWF9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02985 ^@ http://purl.uniprot.org/uniprot/F4LVT7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1209989:TEPRE1_RS07285 ^@ http://purl.uniprot.org/uniprot/F4LVL5 ^@ Function|||Similarity ^@ Belongs to the alpha/beta-type SASP family.|||SASP are bound to spore DNA. They are double-stranded DNA-binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light. http://togogenome.org/gene/1209989:TEPRE1_RS01950 ^@ http://purl.uniprot.org/uniprot/F4LU63 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05490 ^@ http://purl.uniprot.org/uniprot/F4LSY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02040 ^@ http://purl.uniprot.org/uniprot/F4LUN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine-cytosine permease (2.A.39) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12505 ^@ http://purl.uniprot.org/uniprot/F4LUF8 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS01620 ^@ http://purl.uniprot.org/uniprot/F4LU00 ^@ Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Probably a homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS10910 ^@ http://purl.uniprot.org/uniprot/F4LRX0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09650 ^@ http://purl.uniprot.org/uniprot/F4LQR2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS12560 ^@ http://purl.uniprot.org/uniprot/F4LUG9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05715 ^@ http://purl.uniprot.org/uniprot/F4LT27 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS07495 ^@ http://purl.uniprot.org/uniprot/F4LVX4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1209989:TEPRE1_RS00050 ^@ http://purl.uniprot.org/uniprot/F4LRG2 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1209989:TEPRE1_RS08040 ^@ http://purl.uniprot.org/uniprot/F4LWF1 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1209989:TEPRE1_RS06065 ^@ http://purl.uniprot.org/uniprot/F4LTN1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CodY family.|||Cytoplasm|||DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor. http://togogenome.org/gene/1209989:TEPRE1_RS05860 ^@ http://purl.uniprot.org/uniprot/F4LTI9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1209989:TEPRE1_RS06955 ^@ http://purl.uniprot.org/uniprot/F4LV09 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07725 ^@ http://purl.uniprot.org/uniprot/F4LW22 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS09955 ^@ http://purl.uniprot.org/uniprot/F4LQX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09150 ^@ http://purl.uniprot.org/uniprot/F4LXN7 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1209989:TEPRE1_RS09810 ^@ http://purl.uniprot.org/uniprot/F4LQU3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/1209989:TEPRE1_RS08580 ^@ http://purl.uniprot.org/uniprot/F4LX54 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1209989:TEPRE1_RS03490 ^@ http://purl.uniprot.org/uniprot/F4LW94 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Cell membrane|||Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08030 ^@ http://purl.uniprot.org/uniprot/F4LWE9 ^@ Similarity ^@ Belongs to the NadC/ModD family. http://togogenome.org/gene/1209989:TEPRE1_RS03100 ^@ http://purl.uniprot.org/uniprot/F4LVV3 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS05710 ^@ http://purl.uniprot.org/uniprot/F4LT26 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS06300 ^@ http://purl.uniprot.org/uniprot/F4LU78 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1209989:TEPRE1_RS12380 ^@ http://purl.uniprot.org/uniprot/F4LTY2 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1209989:TEPRE1_RS05705 ^@ http://purl.uniprot.org/uniprot/F4LT25 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase U4 family.|||Cell membrane|||Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. http://togogenome.org/gene/1209989:TEPRE1_RS11750 ^@ http://purl.uniprot.org/uniprot/F4LT69 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1209989:TEPRE1_RS11845 ^@ http://purl.uniprot.org/uniprot/U4Q9M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03150 ^@ http://purl.uniprot.org/uniprot/F4LW34 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1209989:TEPRE1_RS09355 ^@ http://purl.uniprot.org/uniprot/F4LQK2 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS09385 ^@ http://purl.uniprot.org/uniprot/F4LQK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS12370 ^@ http://purl.uniprot.org/uniprot/F4LTY0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS12130 ^@ http://purl.uniprot.org/uniprot/F4LTT5 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS06435 ^@ http://purl.uniprot.org/uniprot/F4LUA5 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1209989:TEPRE1_RS11265 ^@ http://purl.uniprot.org/uniprot/F4LSJ2 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1209989:TEPRE1_RS05325 ^@ http://purl.uniprot.org/uniprot/F4LSF2 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS08570 ^@ http://purl.uniprot.org/uniprot/F4LX52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08995 ^@ http://purl.uniprot.org/uniprot/F4LXK6 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1209989:TEPRE1_RS08600 ^@ http://purl.uniprot.org/uniprot/F4LX58 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/1209989:TEPRE1_RS03800 ^@ http://purl.uniprot.org/uniprot/F4LWN1 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. LacC subfamily.|||Belongs to the carbohydrate kinase pfkB family. http://togogenome.org/gene/1209989:TEPRE1_RS12640 ^@ http://purl.uniprot.org/uniprot/F4LUI4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PdxS/SNZ family.|||Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.|||In the presence of PdxT, forms a dodecamer of heterodimers. http://togogenome.org/gene/1209989:TEPRE1_RS08650 ^@ http://purl.uniprot.org/uniprot/F4LX68 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1209989:TEPRE1_RS08445 ^@ http://purl.uniprot.org/uniprot/F4LWV3 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/1209989:TEPRE1_RS05955 ^@ http://purl.uniprot.org/uniprot/F4LTK9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS06200 ^@ http://purl.uniprot.org/uniprot/F4LTQ8 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/1209989:TEPRE1_RS08050 ^@ http://purl.uniprot.org/uniprot/F4LWF3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1209989:TEPRE1_RS09495 ^@ http://purl.uniprot.org/uniprot/F4LQN1 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1209989:TEPRE1_RS06735 ^@ http://purl.uniprot.org/uniprot/F4LUW4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS07105 ^@ http://purl.uniprot.org/uniprot/F4LVH9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1209989:TEPRE1_RS12865 ^@ http://purl.uniprot.org/uniprot/F4LV30 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS02500 ^@ http://purl.uniprot.org/uniprot/F4LVC2 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1209989:TEPRE1_RS05360 ^@ http://purl.uniprot.org/uniprot/F4LSF9 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1209989:TEPRE1_RS00165 ^@ http://purl.uniprot.org/uniprot/F4LRI4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS13055 ^@ http://purl.uniprot.org/uniprot/F4LV65 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS13315 ^@ http://purl.uniprot.org/uniprot/U4QL35 ^@ Similarity ^@ Belongs to the 'phage' integrase family. http://togogenome.org/gene/1209989:TEPRE1_RS02560 ^@ http://purl.uniprot.org/uniprot/F4LVD4 ^@ Similarity ^@ Belongs to the V-ATPase E subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS10680 ^@ http://purl.uniprot.org/uniprot/F4LRD4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the KduI family.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of 5-dehydro-4-deoxy-D-glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. http://togogenome.org/gene/1209989:TEPRE1_RS05555 ^@ http://purl.uniprot.org/uniprot/F4LSZ5 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1209989:TEPRE1_RS07655 ^@ http://purl.uniprot.org/uniprot/F4LW08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1209989:TEPRE1_RS12630 ^@ http://purl.uniprot.org/uniprot/F4LUI2 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS12485 ^@ http://purl.uniprot.org/uniprot/F4LUF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS11285 ^@ http://purl.uniprot.org/uniprot/F4LSJ6 ^@ Similarity ^@ Belongs to the CitG/MdcB family. http://togogenome.org/gene/1209989:TEPRE1_RS09460 ^@ http://purl.uniprot.org/uniprot/F4LQM4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ApbE family.|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1209989:TEPRE1_RS05000 ^@ http://purl.uniprot.org/uniprot/F4LRT4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03795 ^@ http://purl.uniprot.org/uniprot/F4LWN0 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1209989:TEPRE1_RS01670 ^@ http://purl.uniprot.org/uniprot/L0RZK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08060 ^@ http://purl.uniprot.org/uniprot/F4LWF5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS12845 ^@ http://purl.uniprot.org/uniprot/F4LV26 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07980 ^@ http://purl.uniprot.org/uniprot/F4LWE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS07520 ^@ http://purl.uniprot.org/uniprot/F4LVX9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00985 ^@ http://purl.uniprot.org/uniprot/F4LSU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS14065 ^@ http://purl.uniprot.org/uniprot/F4LQU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1209989:TEPRE1_RS07460 ^@ http://purl.uniprot.org/uniprot/F4LVW7 ^@ Similarity ^@ Belongs to the UPF0735 family. http://togogenome.org/gene/1209989:TEPRE1_RS08690 ^@ http://purl.uniprot.org/uniprot/F4LX77 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS10280 ^@ http://purl.uniprot.org/uniprot/F4LR37 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1209989:TEPRE1_RS11695 ^@ http://purl.uniprot.org/uniprot/F4LT58 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1209989:TEPRE1_RS11335 ^@ http://purl.uniprot.org/uniprot/F4LSK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the CitD family.|||Covalent carrier of the coenzyme of citrate lyase.|||Cytoplasm|||Oligomer with a subunit composition of (alpha,beta,gamma)6. http://togogenome.org/gene/1209989:TEPRE1_RS12195 ^@ http://purl.uniprot.org/uniprot/F4LTU7 ^@ Similarity ^@ Belongs to the DNA polymerase type-A family. http://togogenome.org/gene/1209989:TEPRE1_RS08930 ^@ http://purl.uniprot.org/uniprot/F4LXJ3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1209989:TEPRE1_RS02570 ^@ http://purl.uniprot.org/uniprot/F4LVD6 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/1209989:TEPRE1_RS08770 ^@ http://purl.uniprot.org/uniprot/F4LX90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00665 ^@ http://purl.uniprot.org/uniprot/F4LS79 ^@ Similarity ^@ Belongs to the manganese catalase family. http://togogenome.org/gene/1209989:TEPRE1_RS02330 ^@ http://purl.uniprot.org/uniprot/F4LUU6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS11685 ^@ http://purl.uniprot.org/uniprot/F4LT56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09930 ^@ http://purl.uniprot.org/uniprot/F4LQW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Catalyzes phosphorolysis of the pyrimidine nucleosides uridine, thymidine and 2'-deoxyuridine with the formation of the corresponding pyrimidine base and ribose-1-phosphate.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS07985 ^@ http://purl.uniprot.org/uniprot/F4LWE1 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS01365 ^@ http://purl.uniprot.org/uniprot/F4LTE5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03320 ^@ http://purl.uniprot.org/uniprot/F4LW67 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1209989:TEPRE1_RS10825 ^@ http://purl.uniprot.org/uniprot/F4LRF6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the thymidylate synthase ThyX family.|||Binds 4 FAD per tetramer. Each FAD binding site is formed by three monomers.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS12310 ^@ http://purl.uniprot.org/uniprot/F4LTW9 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS05975 ^@ http://purl.uniprot.org/uniprot/F4LTL3 ^@ Function|||Similarity ^@ Belongs to the UPF0122 family.|||Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein. http://togogenome.org/gene/1209989:TEPRE1_RS03535 ^@ http://purl.uniprot.org/uniprot/F4LWH8 ^@ Function|||Similarity|||Subunit ^@ Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha-keto acid in the first half-reaction.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS08110 ^@ http://purl.uniprot.org/uniprot/F4LWG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1209989:TEPRE1_RS05685 ^@ http://purl.uniprot.org/uniprot/F4LT21 ^@ Similarity ^@ Belongs to the UPF0749 family. http://togogenome.org/gene/1209989:TEPRE1_RS07865 ^@ http://purl.uniprot.org/uniprot/F4LWB6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS13165 ^@ http://purl.uniprot.org/uniprot/F4LV87 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07790 ^@ http://purl.uniprot.org/uniprot/F4LWA1 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1209989:TEPRE1_RS02285 ^@ http://purl.uniprot.org/uniprot/F4LUT7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS05450 ^@ http://purl.uniprot.org/uniprot/F4LSH7 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1209989:TEPRE1_RS10405 ^@ http://purl.uniprot.org/uniprot/F4LR62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12700 ^@ http://purl.uniprot.org/uniprot/F4LUJ6 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1209989:TEPRE1_RS07665 ^@ http://purl.uniprot.org/uniprot/F4LW10 ^@ Function|||Similarity ^@ Belongs to the MinE family.|||Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. http://togogenome.org/gene/1209989:TEPRE1_RS10035 ^@ http://purl.uniprot.org/uniprot/F4LQY9 ^@ Similarity ^@ Belongs to the creatininase superfamily. http://togogenome.org/gene/1209989:TEPRE1_RS10740 ^@ http://purl.uniprot.org/uniprot/F4LRE3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1209989:TEPRE1_RS04200 ^@ http://purl.uniprot.org/uniprot/F4LX33 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS01960 ^@ http://purl.uniprot.org/uniprot/F4LU65 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1209989:TEPRE1_RS07750 ^@ http://purl.uniprot.org/uniprot/F4LW25 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS10290 ^@ http://purl.uniprot.org/uniprot/F4LR39 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1209989:TEPRE1_RS08470 ^@ http://purl.uniprot.org/uniprot/F4LWV8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS03580 ^@ http://purl.uniprot.org/uniprot/F4LWI7 ^@ Similarity ^@ Belongs to the UPF0342 family. http://togogenome.org/gene/1209989:TEPRE1_RS03625 ^@ http://purl.uniprot.org/uniprot/F4LWJ6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS01145 ^@ http://purl.uniprot.org/uniprot/F4LSX6 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS01830 ^@ http://purl.uniprot.org/uniprot/F4LU41 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS08830 ^@ http://purl.uniprot.org/uniprot/F4LXA2 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1209989:TEPRE1_RS02340 ^@ http://purl.uniprot.org/uniprot/F4LUU8 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS12815 ^@ http://purl.uniprot.org/uniprot/F4LUM0 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS01570 ^@ http://purl.uniprot.org/uniprot/F4LTI5 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1209989:TEPRE1_RS04790 ^@ http://purl.uniprot.org/uniprot/F4LRP3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS11620 ^@ http://purl.uniprot.org/uniprot/F4LSQ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1209989:TEPRE1_RS09215 ^@ http://purl.uniprot.org/uniprot/F4LXP9 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1209989:TEPRE1_RS11360 ^@ http://purl.uniprot.org/uniprot/F4LSK9 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1209989:TEPRE1_RS09670 ^@ http://purl.uniprot.org/uniprot/F4LQR6 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS05625 ^@ http://purl.uniprot.org/uniprot/F4LT09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS13155 ^@ http://purl.uniprot.org/uniprot/F4LV85 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS09970 ^@ http://purl.uniprot.org/uniprot/F4LQX5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the diaminopimelate dehydrogenase family.|||Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L-tetrahydrodipicolinate, to generate the meso compound, D,L-2,6-diaminopimelate.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS10505 ^@ http://purl.uniprot.org/uniprot/F4LR99 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1209989:TEPRE1_RS11085 ^@ http://purl.uniprot.org/uniprot/F4LS06 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/1209989:TEPRE1_RS06720 ^@ http://purl.uniprot.org/uniprot/F4LUW1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS08010 ^@ http://purl.uniprot.org/uniprot/F4LWE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08955 ^@ http://purl.uniprot.org/uniprot/F4LXJ8 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1209989:TEPRE1_RS02390 ^@ http://purl.uniprot.org/uniprot/F4LVA1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1209989:TEPRE1_RS03610 ^@ http://purl.uniprot.org/uniprot/L0RZ18 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-C family. DnaE subfamily.|||Cytoplasm|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase. http://togogenome.org/gene/1209989:TEPRE1_RS03620 ^@ http://purl.uniprot.org/uniprot/F4LWJ5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10925 ^@ http://purl.uniprot.org/uniprot/F4LRX3 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS07210 ^@ http://purl.uniprot.org/uniprot/F4LVK0 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1209989:TEPRE1_RS06595 ^@ http://purl.uniprot.org/uniprot/F4LUD7 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1209989:TEPRE1_RS10155 ^@ http://purl.uniprot.org/uniprot/F4LR13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS02250 ^@ http://purl.uniprot.org/uniprot/F4LUT0 ^@ Caution|||Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1209989:TEPRE1_RS06105 ^@ http://purl.uniprot.org/uniprot/F4LTN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12345 ^@ http://purl.uniprot.org/uniprot/F4LTX5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10420 ^@ http://purl.uniprot.org/uniprot/F4LR65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06020 ^@ http://purl.uniprot.org/uniprot/F4LTM2 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1209989:TEPRE1_RS11250 ^@ http://purl.uniprot.org/uniprot/F4LSI9 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1209989:TEPRE1_RS02895 ^@ http://purl.uniprot.org/uniprot/F4LVS2 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1209989:TEPRE1_RS08120 ^@ http://purl.uniprot.org/uniprot/F4LWG5 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1209989:TEPRE1_RS07215 ^@ http://purl.uniprot.org/uniprot/F4LVK1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS11830 ^@ http://purl.uniprot.org/uniprot/U4Q9M7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1209989:TEPRE1_RS09590 ^@ http://purl.uniprot.org/uniprot/F4LQQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07670 ^@ http://purl.uniprot.org/uniprot/F4LW11 ^@ Function|||Similarity ^@ ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.|||Belongs to the ParA family. MinD subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS11420 ^@ http://purl.uniprot.org/uniprot/F4LSM1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1209989:TEPRE1_RS06840 ^@ http://purl.uniprot.org/uniprot/F4LUY5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07425 ^@ http://purl.uniprot.org/uniprot/F4LVW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SepF family.|||Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.|||Cytoplasm|||Homodimer. Interacts with FtsZ. http://togogenome.org/gene/1209989:TEPRE1_RS10365 ^@ http://purl.uniprot.org/uniprot/F4LR54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11785 ^@ http://purl.uniprot.org/uniprot/F4LT76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06905 ^@ http://purl.uniprot.org/uniprot/F4LUZ9 ^@ Function|||Similarity ^@ Belongs to the anti-sigma-factor antagonist family.|||In the phosphorylated form it could act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma f from inhibition. http://togogenome.org/gene/1209989:TEPRE1_RS03855 ^@ http://purl.uniprot.org/uniprot/F4LWP1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS10485 ^@ http://purl.uniprot.org/uniprot/F4LR95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04360 ^@ http://purl.uniprot.org/uniprot/F4LXD7 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS00005 ^@ http://purl.uniprot.org/uniprot/F4LR73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1209989:TEPRE1_RS00945 ^@ http://purl.uniprot.org/uniprot/F4LST6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS07115 ^@ http://purl.uniprot.org/uniprot/F4LVI1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS06660 ^@ http://purl.uniprot.org/uniprot/F4LUV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1209989:TEPRE1_RS01590 ^@ http://purl.uniprot.org/uniprot/F4LTZ4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10745 ^@ http://purl.uniprot.org/uniprot/F4LRE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1209989:TEPRE1_RS03275 ^@ http://purl.uniprot.org/uniprot/F4LW59 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS07255 ^@ http://purl.uniprot.org/uniprot/F4LVK9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcAL family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac-AMP) and then transfers the acetyl group to tRNA to form ac(4)C34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS02585 ^@ http://purl.uniprot.org/uniprot/F4LVD9 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1209989:TEPRE1_RS02260 ^@ http://purl.uniprot.org/uniprot/F4LUT2 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1209989:TEPRE1_RS03105 ^@ http://purl.uniprot.org/uniprot/F4LVV4 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1209989:TEPRE1_RS06715 ^@ http://purl.uniprot.org/uniprot/F4LUW0 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain. http://togogenome.org/gene/1209989:TEPRE1_RS04370 ^@ http://purl.uniprot.org/uniprot/F4LXD9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04980 ^@ http://purl.uniprot.org/uniprot/F4LRT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00560 ^@ http://purl.uniprot.org/uniprot/F4LS60 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the methylaspartate mutase GlmS subunit family.|||Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate).|||Heterotetramer composed of 2 epsilon subunits (GlmE) and 2 sigma subunits (GlmS). GlmE exists as a homodimer and GlmS as a monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07055 ^@ http://purl.uniprot.org/uniprot/F4LVG9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1209989:TEPRE1_RS01520 ^@ http://purl.uniprot.org/uniprot/F4LTH5 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1209989:TEPRE1_RS03260 ^@ http://purl.uniprot.org/uniprot/F4LW56 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS03365 ^@ http://purl.uniprot.org/uniprot/F4LW75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS11900 ^@ http://purl.uniprot.org/uniprot/F4LT91 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS09375 ^@ http://purl.uniprot.org/uniprot/F4LQK7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS07685 ^@ http://purl.uniprot.org/uniprot/F4LW14 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10345 ^@ http://purl.uniprot.org/uniprot/F4LR50 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit. http://togogenome.org/gene/1209989:TEPRE1_RS09815 ^@ http://purl.uniprot.org/uniprot/F4LQU4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08835 ^@ http://purl.uniprot.org/uniprot/F4LXA3 ^@ Similarity ^@ Belongs to the P-Pant transferase superfamily. Gsp/Sfp/HetI/AcpT family. http://togogenome.org/gene/1209989:TEPRE1_RS07125 ^@ http://purl.uniprot.org/uniprot/F4LVI3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1209989:TEPRE1_RS05665 ^@ http://purl.uniprot.org/uniprot/F4LT17 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS00350 ^@ http://purl.uniprot.org/uniprot/F4LRL9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS08490 ^@ http://purl.uniprot.org/uniprot/F4LWW2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS08505 ^@ http://purl.uniprot.org/uniprot/F4LWW5 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS06085 ^@ http://purl.uniprot.org/uniprot/F4LTN5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1209989:TEPRE1_RS13050 ^@ http://purl.uniprot.org/uniprot/F4LV64 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1209989:TEPRE1_RS09415 ^@ http://purl.uniprot.org/uniprot/F4LQL5 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1209989:TEPRE1_RS07500 ^@ http://purl.uniprot.org/uniprot/F4LVX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11155 ^@ http://purl.uniprot.org/uniprot/F4LS21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02870 ^@ http://purl.uniprot.org/uniprot/F4LVR7 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1209989:TEPRE1_RS02940 ^@ http://purl.uniprot.org/uniprot/F4LVT1 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1209989:TEPRE1_RS03965 ^@ http://purl.uniprot.org/uniprot/F4LWY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10525 ^@ http://purl.uniprot.org/uniprot/F4LRA3 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1209989:TEPRE1_RS12715 ^@ http://purl.uniprot.org/uniprot/F4LUJ9 ^@ Function|||Similarity ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). http://togogenome.org/gene/1209989:TEPRE1_RS00545 ^@ http://purl.uniprot.org/uniprot/F4LS58 ^@ Similarity ^@ In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.|||In the central section; belongs to the CRISPR-associated helicase Cas3 family. http://togogenome.org/gene/1209989:TEPRE1_RS00550 ^@ http://purl.uniprot.org/uniprot/F4LS59 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS08360 ^@ http://purl.uniprot.org/uniprot/F4LWT6 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 26 family. TagA/TarA subfamily.|||Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid. http://togogenome.org/gene/1209989:TEPRE1_RS07560 ^@ http://purl.uniprot.org/uniprot/F4LVY8 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1209989:TEPRE1_RS06675 ^@ http://purl.uniprot.org/uniprot/F4LUV6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS03910 ^@ http://purl.uniprot.org/uniprot/F4LWX7 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1209989:TEPRE1_RS08620 ^@ http://purl.uniprot.org/uniprot/F4LX62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02410 ^@ http://purl.uniprot.org/uniprot/F4LVA5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS01085 ^@ http://purl.uniprot.org/uniprot/F4LSW4 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1209989:TEPRE1_RS09935 ^@ http://purl.uniprot.org/uniprot/F4LQW8 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1209989:TEPRE1_RS07675 ^@ http://purl.uniprot.org/uniprot/F4LW12 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MinC family.|||Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.|||Interacts with MinD and FtsZ. http://togogenome.org/gene/1209989:TEPRE1_RS05560 ^@ http://purl.uniprot.org/uniprot/F4LSZ6 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS11365 ^@ http://purl.uniprot.org/uniprot/F4LSL0 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1209989:TEPRE1_RS07875 ^@ http://purl.uniprot.org/uniprot/F4LWB8 ^@ Function|||Similarity|||Subunit ^@ Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization.|||Belongs to the HutP family.|||Homohexamer. http://togogenome.org/gene/1209989:TEPRE1_RS11790 ^@ http://purl.uniprot.org/uniprot/F4LT77 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1209989:TEPRE1_RS06035 ^@ http://purl.uniprot.org/uniprot/F4LTM5 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1209989:TEPRE1_RS01900 ^@ http://purl.uniprot.org/uniprot/F4LU53 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07475 ^@ http://purl.uniprot.org/uniprot/F4LVX0 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1209989:TEPRE1_RS04595 ^@ http://purl.uniprot.org/uniprot/F4LXI0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS06845 ^@ http://purl.uniprot.org/uniprot/F4LUY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01955 ^@ http://purl.uniprot.org/uniprot/F4LU64 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02490 ^@ http://purl.uniprot.org/uniprot/F4LVC1 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1209989:TEPRE1_RS06320 ^@ http://purl.uniprot.org/uniprot/F4LU82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1209989:TEPRE1_RS10300 ^@ http://purl.uniprot.org/uniprot/F4LR41 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS09390 ^@ http://purl.uniprot.org/uniprot/F4LQL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS04985 ^@ http://purl.uniprot.org/uniprot/F4LRT1 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS03780 ^@ http://purl.uniprot.org/uniprot/F4LWM7 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1209989:TEPRE1_RS08920 ^@ http://purl.uniprot.org/uniprot/F4LXC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10515 ^@ http://purl.uniprot.org/uniprot/F4LRA1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1209989:TEPRE1_RS06420 ^@ http://purl.uniprot.org/uniprot/F4LUA2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS10250 ^@ http://purl.uniprot.org/uniprot/F4LR32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11765 ^@ http://purl.uniprot.org/uniprot/F4LT72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/1209989:TEPRE1_RS07275 ^@ http://purl.uniprot.org/uniprot/F4LVL3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1209989:TEPRE1_RS05400 ^@ http://purl.uniprot.org/uniprot/F4LSG7 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1209989:TEPRE1_RS08430 ^@ http://purl.uniprot.org/uniprot/F4LWV0 ^@ Function|||Similarity ^@ Belongs to the LarC family.|||Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2+), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor-dependent enzymes. http://togogenome.org/gene/1209989:TEPRE1_RS05990 ^@ http://purl.uniprot.org/uniprot/F4LTL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1209989:TEPRE1_RS00825 ^@ http://purl.uniprot.org/uniprot/F4LSR2 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS05695 ^@ http://purl.uniprot.org/uniprot/F4LT23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1209989:TEPRE1_RS06015 ^@ http://purl.uniprot.org/uniprot/F4LTM1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1209989:TEPRE1_RS10395 ^@ http://purl.uniprot.org/uniprot/F4LR60 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. SigI subfamily.|||Cytoplasm|||Interacts with RsgI.|||Negatively regulated by the anti-sigma-I factor RsgI.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS08140 ^@ http://purl.uniprot.org/uniprot/F4LWG9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the anthranilate synthase component I family.|||Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).|||Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. http://togogenome.org/gene/1209989:TEPRE1_RS11950 ^@ http://purl.uniprot.org/uniprot/F4LT97 ^@ Similarity ^@ Belongs to the PemK/MazF family. http://togogenome.org/gene/1209989:TEPRE1_RS10650 ^@ http://purl.uniprot.org/uniprot/F4LRC8 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1209989:TEPRE1_RS04895 ^@ http://purl.uniprot.org/uniprot/F4LRR3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS11325 ^@ http://purl.uniprot.org/uniprot/F4LSK2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS08965 ^@ http://purl.uniprot.org/uniprot/F4LXK0 ^@ Similarity ^@ In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family. http://togogenome.org/gene/1209989:TEPRE1_RS00915 ^@ http://purl.uniprot.org/uniprot/F4LST0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1209989:TEPRE1_RS00090 ^@ http://purl.uniprot.org/uniprot/F4LRH0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1209989:TEPRE1_RS12520 ^@ http://purl.uniprot.org/uniprot/F4LUG1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1209989:TEPRE1_RS10045 ^@ http://purl.uniprot.org/uniprot/F4LQZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06075 ^@ http://purl.uniprot.org/uniprot/F4LTN3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1209989:TEPRE1_RS05675 ^@ http://purl.uniprot.org/uniprot/F4LT19 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS06990 ^@ http://purl.uniprot.org/uniprot/F4LV16 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1209989:TEPRE1_RS06305 ^@ http://purl.uniprot.org/uniprot/F4LU79 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS08145 ^@ http://purl.uniprot.org/uniprot/F4LWH1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1209989:TEPRE1_RS10600 ^@ http://purl.uniprot.org/uniprot/F4LRB8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS12475 ^@ http://purl.uniprot.org/uniprot/F4LUF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10620 ^@ http://purl.uniprot.org/uniprot/F4LRC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS05940 ^@ http://purl.uniprot.org/uniprot/F4LTK6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS12455 ^@ http://purl.uniprot.org/uniprot/F4LUE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12260 ^@ http://purl.uniprot.org/uniprot/F4LTV9 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/1209989:TEPRE1_RS01395 ^@ http://purl.uniprot.org/uniprot/F4LTF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02845 ^@ http://purl.uniprot.org/uniprot/F4LVR2 ^@ Activity Regulation|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1209989:TEPRE1_RS03940 ^@ http://purl.uniprot.org/uniprot/F4LWY3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS08865 ^@ http://purl.uniprot.org/uniprot/F4LXA9 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1209989:TEPRE1_RS00405 ^@ http://purl.uniprot.org/uniprot/F4LRN0 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1209989:TEPRE1_RS03010 ^@ http://purl.uniprot.org/uniprot/F4LVU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1209989:TEPRE1_RS05890 ^@ http://purl.uniprot.org/uniprot/F4LTJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YajC family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04090 ^@ http://purl.uniprot.org/uniprot/F4LX13 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS05760 ^@ http://purl.uniprot.org/uniprot/F4LT36 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1209989:TEPRE1_RS05050 ^@ http://purl.uniprot.org/uniprot/F4LRU4 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS06070 ^@ http://purl.uniprot.org/uniprot/F4LTN2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1209989:TEPRE1_RS09180 ^@ http://purl.uniprot.org/uniprot/F4LXP3 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS05340 ^@ http://purl.uniprot.org/uniprot/F4LSF5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FGAMS family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1209989:TEPRE1_RS06370 ^@ http://purl.uniprot.org/uniprot/F4LU92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1209989:TEPRE1_RS06650 ^@ http://purl.uniprot.org/uniprot/F4LUV0 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS10215 ^@ http://purl.uniprot.org/uniprot/F4LR25 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS12905 ^@ http://purl.uniprot.org/uniprot/F4LV39 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS06180 ^@ http://purl.uniprot.org/uniprot/F4LTQ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1209989:TEPRE1_RS05875 ^@ http://purl.uniprot.org/uniprot/F4LTJ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1209989:TEPRE1_RS02025 ^@ http://purl.uniprot.org/uniprot/F4LUN6 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1209989:TEPRE1_RS09010 ^@ http://purl.uniprot.org/uniprot/F4LXK9 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1209989:TEPRE1_RS01425 ^@ http://purl.uniprot.org/uniprot/F4LTF6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1209989:TEPRE1_RS02055 ^@ http://purl.uniprot.org/uniprot/F4LUP2 ^@ Similarity ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS03885 ^@ http://purl.uniprot.org/uniprot/F4LWP8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS01695 ^@ http://purl.uniprot.org/uniprot/F4LU15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS06835 ^@ http://purl.uniprot.org/uniprot/F4LUY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ScpA family.|||Component of a cohesin-like complex composed of ScpA, ScpB and the Smc homodimer, in which ScpA and ScpB bind to the head domain of Smc. The presence of the three proteins is required for the association of the complex with DNA.|||Cytoplasm|||Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves. http://togogenome.org/gene/1209989:TEPRE1_RS02335 ^@ http://purl.uniprot.org/uniprot/F4LUU7 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.|||Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS12495 ^@ http://purl.uniprot.org/uniprot/F4LUF6 ^@ Caution|||Function|||Similarity ^@ Belongs to the type IA topoisomerase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1209989:TEPRE1_RS11010 ^@ http://purl.uniprot.org/uniprot/F4LRZ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05920 ^@ http://purl.uniprot.org/uniprot/F4LTK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1209989:TEPRE1_RS10360 ^@ http://purl.uniprot.org/uniprot/F4LR53 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1209989:TEPRE1_RS02400 ^@ http://purl.uniprot.org/uniprot/F4LVA3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1209989:TEPRE1_RS01870 ^@ http://purl.uniprot.org/uniprot/F4LU47 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS05835 ^@ http://purl.uniprot.org/uniprot/F4LT45 ^@ Similarity ^@ Belongs to the IMPACT family. http://togogenome.org/gene/1209989:TEPRE1_RS09640 ^@ http://purl.uniprot.org/uniprot/F4LQR0 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS09430 ^@ http://purl.uniprot.org/uniprot/F4LQL8 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1209989:TEPRE1_RS00730 ^@ http://purl.uniprot.org/uniprot/F4LS93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family.|||Cell membrane|||Membrane|||Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. http://togogenome.org/gene/1209989:TEPRE1_RS08875 ^@ http://purl.uniprot.org/uniprot/F4LXB1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01360 ^@ http://purl.uniprot.org/uniprot/F4LTE4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06130 ^@ http://purl.uniprot.org/uniprot/L0RYH8 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1209989:TEPRE1_RS11015 ^@ http://purl.uniprot.org/uniprot/F4LRZ2 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Non-allosteric. http://togogenome.org/gene/1209989:TEPRE1_RS00085 ^@ http://purl.uniprot.org/uniprot/F4LRG9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS01380 ^@ http://purl.uniprot.org/uniprot/F4LTE8 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1209989:TEPRE1_RS03745 ^@ http://purl.uniprot.org/uniprot/F4LWM0 ^@ Similarity ^@ Belongs to the GerABKC lipoprotein family. http://togogenome.org/gene/1209989:TEPRE1_RS03545 ^@ http://purl.uniprot.org/uniprot/F4LWI0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS03140 ^@ http://purl.uniprot.org/uniprot/F4LW32 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS06525 ^@ http://purl.uniprot.org/uniprot/F4LUC3 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS10495 ^@ http://purl.uniprot.org/uniprot/F4LR97 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1209989:TEPRE1_RS02190 ^@ http://purl.uniprot.org/uniprot/F4LUR8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS04935 ^@ http://purl.uniprot.org/uniprot/F4LRS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1209989:TEPRE1_RS04915 ^@ http://purl.uniprot.org/uniprot/F4LRR7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1209989:TEPRE1_RS08410 ^@ http://purl.uniprot.org/uniprot/F4LWU6 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1209989:TEPRE1_RS11090 ^@ http://purl.uniprot.org/uniprot/F4LS07 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1209989:TEPRE1_RS12500 ^@ http://purl.uniprot.org/uniprot/F4LUF7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10010 ^@ http://purl.uniprot.org/uniprot/F4LQY4 ^@ Similarity ^@ Belongs to the UPF0340 family. http://togogenome.org/gene/1209989:TEPRE1_RS12750 ^@ http://purl.uniprot.org/uniprot/F4LUK7 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1209989:TEPRE1_RS09290 ^@ http://purl.uniprot.org/uniprot/U4QL53 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS03425 ^@ http://purl.uniprot.org/uniprot/F4LW80 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07550 ^@ http://purl.uniprot.org/uniprot/F4LVY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS10105 ^@ http://purl.uniprot.org/uniprot/F4LR03 ^@ Caution|||Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS05495 ^@ http://purl.uniprot.org/uniprot/F4LSY3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes. http://togogenome.org/gene/1209989:TEPRE1_RS09910 ^@ http://purl.uniprot.org/uniprot/F4LQW3 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS10265 ^@ http://purl.uniprot.org/uniprot/F4LR34 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS05375 ^@ http://purl.uniprot.org/uniprot/F4LSG2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1209989:TEPRE1_RS12705 ^@ http://purl.uniprot.org/uniprot/F4LUJ7 ^@ Similarity ^@ Belongs to the EamA transporter family. http://togogenome.org/gene/1209989:TEPRE1_RS00515 ^@ http://purl.uniprot.org/uniprot/F4LS52 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1209989:TEPRE1_RS01435 ^@ http://purl.uniprot.org/uniprot/F4LTF8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1209989:TEPRE1_RS00510 ^@ http://purl.uniprot.org/uniprot/F4LS51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11930 ^@ http://purl.uniprot.org/uniprot/F4LT95 ^@ Similarity ^@ Belongs to the RelB/DinJ antitoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS00445 ^@ http://purl.uniprot.org/uniprot/F4LS38 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/1209989:TEPRE1_RS00260 ^@ http://purl.uniprot.org/uniprot/F4LRK2 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1209989:TEPRE1_RS12730 ^@ http://purl.uniprot.org/uniprot/F4LUK2 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1209989:TEPRE1_RS05460 ^@ http://purl.uniprot.org/uniprot/F4LSH9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1209989:TEPRE1_RS06635 ^@ http://purl.uniprot.org/uniprot/F4LUE5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1209989:TEPRE1_RS01355 ^@ http://purl.uniprot.org/uniprot/F4LTE3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS00975 ^@ http://purl.uniprot.org/uniprot/F4LSU2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1209989:TEPRE1_RS05335 ^@ http://purl.uniprot.org/uniprot/F4LSF4 ^@ Caution|||Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.|||Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL. http://togogenome.org/gene/1209989:TEPRE1_RS10890 ^@ http://purl.uniprot.org/uniprot/F4LRW6 ^@ Similarity ^@ Belongs to the CtsR family. http://togogenome.org/gene/1209989:TEPRE1_RS04330 ^@ http://purl.uniprot.org/uniprot/F4LXD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1209989:TEPRE1_RS04885 ^@ http://purl.uniprot.org/uniprot/F4LRR1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12280 ^@ http://purl.uniprot.org/uniprot/F4LTW3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS10775 ^@ http://purl.uniprot.org/uniprot/F4LRF0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1209989:TEPRE1_RS06195 ^@ http://purl.uniprot.org/uniprot/F4LTQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1209989:TEPRE1_RS10630 ^@ http://purl.uniprot.org/uniprot/F4LRC4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1209989:TEPRE1_RS08585 ^@ http://purl.uniprot.org/uniprot/F4LX55 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02305 ^@ http://purl.uniprot.org/uniprot/F4LUU1 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1209989:TEPRE1_RS06000 ^@ http://purl.uniprot.org/uniprot/F4LTL8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1209989:TEPRE1_RS03785 ^@ http://purl.uniprot.org/uniprot/F4LWM8 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1209989:TEPRE1_RS09665 ^@ http://purl.uniprot.org/uniprot/F4LQR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS01390 ^@ http://purl.uniprot.org/uniprot/F4LTE9 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1209989:TEPRE1_RS07925 ^@ http://purl.uniprot.org/uniprot/F4LWC8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10755 ^@ http://purl.uniprot.org/uniprot/F4LRE6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1209989:TEPRE1_RS12820 ^@ http://purl.uniprot.org/uniprot/F4LUM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03525 ^@ http://purl.uniprot.org/uniprot/F4LWH6 ^@ Similarity ^@ Belongs to the PGI/PMI family. http://togogenome.org/gene/1209989:TEPRE1_RS07300 ^@ http://purl.uniprot.org/uniprot/F4LVL8 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1209989:TEPRE1_RS07690 ^@ http://purl.uniprot.org/uniprot/F4LW15 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1209989:TEPRE1_RS08480 ^@ http://purl.uniprot.org/uniprot/F4LWW0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS05430 ^@ http://purl.uniprot.org/uniprot/F4LSH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1209989:TEPRE1_RS13070 ^@ http://purl.uniprot.org/uniprot/F4LV68 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1209989:TEPRE1_RS05635 ^@ http://purl.uniprot.org/uniprot/F4LT11 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/1209989:TEPRE1_RS02800 ^@ http://purl.uniprot.org/uniprot/F4LVQ3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1209989:TEPRE1_RS02480 ^@ http://purl.uniprot.org/uniprot/F4LVB9 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1209989:TEPRE1_RS10930 ^@ http://purl.uniprot.org/uniprot/F4LRX4 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1209989:TEPRE1_RS04350 ^@ http://purl.uniprot.org/uniprot/F4LXD5 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. L-methionine gamma-lyase subfamily. http://togogenome.org/gene/1209989:TEPRE1_RS01245 ^@ http://purl.uniprot.org/uniprot/F4LTC5 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/1209989:TEPRE1_RS05765 ^@ http://purl.uniprot.org/uniprot/F4LT37 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS10080 ^@ http://purl.uniprot.org/uniprot/F4LQZ7 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1209989:TEPRE1_RS11035 ^@ http://purl.uniprot.org/uniprot/F4LRZ6 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Activated by phosphorylation and inhibited by fructose 1,6-bisphosphate (FBP).|||Belongs to the FGGY kinase family.|||Homotetramer and homodimer (in equilibrium).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS05640 ^@ http://purl.uniprot.org/uniprot/F4LT12 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS03480 ^@ http://purl.uniprot.org/uniprot/F4LW92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS06915 ^@ http://purl.uniprot.org/uniprot/F4LV01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1209989:TEPRE1_RS04940 ^@ http://purl.uniprot.org/uniprot/F4LRS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS08290 ^@ http://purl.uniprot.org/uniprot/F4LWS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell membrane|||Membrane|||Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. http://togogenome.org/gene/1209989:TEPRE1_RS05525 ^@ http://purl.uniprot.org/uniprot/F4LSY9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS05770 ^@ http://purl.uniprot.org/uniprot/F4LT38 ^@ Function|||Subcellular Location Annotation ^@ ATPase. Has a role at an early stage in the morphogenesis of the spore coat.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS06910 ^@ http://purl.uniprot.org/uniprot/F4LV00 ^@ Function|||Similarity ^@ Belongs to the peptidase S11 family.|||Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. http://togogenome.org/gene/1209989:TEPRE1_RS03570 ^@ http://purl.uniprot.org/uniprot/F4LWI5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS04195 ^@ http://purl.uniprot.org/uniprot/F4LX32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1209989:TEPRE1_RS04215 ^@ http://purl.uniprot.org/uniprot/F4LX35 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS07825 ^@ http://purl.uniprot.org/uniprot/F4LWA8 ^@ Cofactor|||Similarity ^@ Belongs to the AlaDH/PNT family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS02470 ^@ http://purl.uniprot.org/uniprot/F4LVB7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1209989:TEPRE1_RS08475 ^@ http://purl.uniprot.org/uniprot/F4LWV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02280 ^@ http://purl.uniprot.org/uniprot/F4LUT6 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS00495 ^@ http://purl.uniprot.org/uniprot/F4LS48 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1209989:TEPRE1_RS08810 ^@ http://purl.uniprot.org/uniprot/F4LX98 ^@ Similarity ^@ Belongs to the FemABX family. http://togogenome.org/gene/1209989:TEPRE1_RS05935 ^@ http://purl.uniprot.org/uniprot/F4LTK5 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1209989:TEPRE1_RS10320 ^@ http://purl.uniprot.org/uniprot/F4LR45 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07375 ^@ http://purl.uniprot.org/uniprot/F4LVN3 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/1209989:TEPRE1_RS08170 ^@ http://purl.uniprot.org/uniprot/F4LWQ2 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1209989:TEPRE1_RS04075 ^@ http://purl.uniprot.org/uniprot/F4LX10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS05455 ^@ http://purl.uniprot.org/uniprot/F4LSH8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1209989:TEPRE1_RS06365 ^@ http://purl.uniprot.org/uniprot/F4LU91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS08300 ^@ http://purl.uniprot.org/uniprot/F4LWS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS10855 ^@ http://purl.uniprot.org/uniprot/F4LRV9 ^@ Similarity ^@ Belongs to the ycf81 family. http://togogenome.org/gene/1209989:TEPRE1_RS07360 ^@ http://purl.uniprot.org/uniprot/F4LVN0 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS00240 ^@ http://purl.uniprot.org/uniprot/F4LRJ9 ^@ Similarity ^@ Belongs to the DSD1 family. http://togogenome.org/gene/1209989:TEPRE1_RS08710 ^@ http://purl.uniprot.org/uniprot/F4LX81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS14000 ^@ http://purl.uniprot.org/uniprot/F4LVT5 ^@ Similarity ^@ Belongs to the UPF0236 family. http://togogenome.org/gene/1209989:TEPRE1_RS10695 ^@ http://purl.uniprot.org/uniprot/F4LRD7 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1209989:TEPRE1_RS00040 ^@ http://purl.uniprot.org/uniprot/F4LR80 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1209989:TEPRE1_RS00095 ^@ http://purl.uniprot.org/uniprot/F4LRH1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03715 ^@ http://purl.uniprot.org/uniprot/F4LWL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MurCDEF family. MurT subfamily.|||Forms a heterodimer with GatD.|||The lipid II isoglutaminyl synthase complex catalyzes the formation of alpha-D-isoglutamine in the cell wall lipid II stem peptide. The MurT subunit catalyzes the ATP-dependent amidation of D-glutamate residue of lipid II, converting it to an isoglutamine residue. http://togogenome.org/gene/1209989:TEPRE1_RS01800 ^@ http://purl.uniprot.org/uniprot/F4LU35 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS09155 ^@ http://purl.uniprot.org/uniprot/F4LXN8 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1209989:TEPRE1_RS03015 ^@ http://purl.uniprot.org/uniprot/F4LVU3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1209989:TEPRE1_RS10470 ^@ http://purl.uniprot.org/uniprot/F4LR92 ^@ Function|||Similarity ^@ Belongs to the NanE family.|||Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P). http://togogenome.org/gene/1209989:TEPRE1_RS05345 ^@ http://purl.uniprot.org/uniprot/F4LSF6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS06360 ^@ http://purl.uniprot.org/uniprot/F4LU90 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1209989:TEPRE1_RS03810 ^@ http://purl.uniprot.org/uniprot/F4LWN3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.|||Cell membrane|||Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.|||The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1209989:TEPRE1_RS05550 ^@ http://purl.uniprot.org/uniprot/F4LSZ4 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1209989:TEPRE1_RS05440 ^@ http://purl.uniprot.org/uniprot/F4LSH5 ^@ Similarity ^@ Belongs to the TCP-1 chaperonin family. http://togogenome.org/gene/1209989:TEPRE1_RS02590 ^@ http://purl.uniprot.org/uniprot/F4LVE0 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1209989:TEPRE1_RS01735 ^@ http://purl.uniprot.org/uniprot/F4LU22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1209989:TEPRE1_RS03465 ^@ http://purl.uniprot.org/uniprot/F4LW89 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1209989:TEPRE1_RS02310 ^@ http://purl.uniprot.org/uniprot/F4LUU2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1209989:TEPRE1_RS02740 ^@ http://purl.uniprot.org/uniprot/K7SWE7 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1209989:TEPRE1_RS10040 ^@ http://purl.uniprot.org/uniprot/F4LQZ0 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1209989:TEPRE1_RS09995 ^@ http://purl.uniprot.org/uniprot/F4LQY0 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS05530 ^@ http://purl.uniprot.org/uniprot/F4LSZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03495 ^@ http://purl.uniprot.org/uniprot/F4LW95 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1209989:TEPRE1_RS10785 ^@ http://purl.uniprot.org/uniprot/F4LRF2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1209989:TEPRE1_RS03555 ^@ http://purl.uniprot.org/uniprot/F4LWI2 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1209989:TEPRE1_RS12680 ^@ http://purl.uniprot.org/uniprot/F4LUJ2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS05885 ^@ http://purl.uniprot.org/uniprot/F4LTJ4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1209989:TEPRE1_RS09075 ^@ http://purl.uniprot.org/uniprot/F4LXM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03925 ^@ http://purl.uniprot.org/uniprot/F4LWY0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07335 ^@ http://purl.uniprot.org/uniprot/F4LVM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1209989:TEPRE1_RS05945 ^@ http://purl.uniprot.org/uniprot/F4LTK7 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS12655 ^@ http://purl.uniprot.org/uniprot/F4LUI7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07205 ^@ http://purl.uniprot.org/uniprot/F4LVJ9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS07365 ^@ http://purl.uniprot.org/uniprot/F4LVN1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1209989:TEPRE1_RS04095 ^@ http://purl.uniprot.org/uniprot/F4LX14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1209989:TEPRE1_RS11100 ^@ http://purl.uniprot.org/uniprot/F4LS09 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS13185 ^@ http://purl.uniprot.org/uniprot/F4LV91 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1209989:TEPRE1_RS10670 ^@ http://purl.uniprot.org/uniprot/F4LRD2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS09800 ^@ http://purl.uniprot.org/uniprot/F4LQU1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09505 ^@ http://purl.uniprot.org/uniprot/F4LQN3 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1209989:TEPRE1_RS08820 ^@ http://purl.uniprot.org/uniprot/F4LXA0 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS00200 ^@ http://purl.uniprot.org/uniprot/F4LRJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06290 ^@ http://purl.uniprot.org/uniprot/F4LU76 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12785 ^@ http://purl.uniprot.org/uniprot/F4LUL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1209989:TEPRE1_RS06190 ^@ http://purl.uniprot.org/uniprot/F4LTQ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1209989:TEPRE1_RS09655 ^@ http://purl.uniprot.org/uniprot/F4LQR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the LeuD family. LeuD type 2 subfamily.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1209989:TEPRE1_RS09105 ^@ http://purl.uniprot.org/uniprot/F4LXM8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/1209989:TEPRE1_RS05790 ^@ http://purl.uniprot.org/uniprot/F4LT42 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1209989:TEPRE1_RS08330 ^@ http://purl.uniprot.org/uniprot/F4LWT0 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1209989:TEPRE1_RS03175 ^@ http://purl.uniprot.org/uniprot/F4LW39 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1209989:TEPRE1_RS03265 ^@ http://purl.uniprot.org/uniprot/F4LW57 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1209989:TEPRE1_RS08960 ^@ http://purl.uniprot.org/uniprot/F4LXJ9 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS08160 ^@ http://purl.uniprot.org/uniprot/F4LWQ0 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1209989:TEPRE1_RS04180 ^@ http://purl.uniprot.org/uniprot/F4LX29 ^@ Similarity ^@ Belongs to the bacterial flagellin family. http://togogenome.org/gene/1209989:TEPRE1_RS00970 ^@ http://purl.uniprot.org/uniprot/F4LSU1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1209989:TEPRE1_RS07775 ^@ http://purl.uniprot.org/uniprot/F4LW28 ^@ Similarity|||Subunit ^@ Belongs to the PdxA family. PdxA2 subfamily.|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS08130 ^@ http://purl.uniprot.org/uniprot/F4LWG7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS13160 ^@ http://purl.uniprot.org/uniprot/F4LV86 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1209989:TEPRE1_RS01115 ^@ http://purl.uniprot.org/uniprot/F4LSX0 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1209989:TEPRE1_RS07535 ^@ http://purl.uniprot.org/uniprot/F4LVY2 ^@ Caution|||Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS01865 ^@ http://purl.uniprot.org/uniprot/F4LU46 ^@ Similarity ^@ Belongs to the asp23 family. http://togogenome.org/gene/1209989:TEPRE1_RS00310 ^@ http://purl.uniprot.org/uniprot/F4LRL1 ^@ Function|||Similarity ^@ Belongs to the ROK (NagC/XylR) family.|||Transcriptional repressor of xylose-utilizing enzymes. http://togogenome.org/gene/1209989:TEPRE1_RS02200 ^@ http://purl.uniprot.org/uniprot/F4LUS0 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1209989:TEPRE1_RS08990 ^@ http://purl.uniprot.org/uniprot/F4LXK5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1209989:TEPRE1_RS07100 ^@ http://purl.uniprot.org/uniprot/F4LVH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS02900 ^@ http://purl.uniprot.org/uniprot/F4LVS3 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1209989:TEPRE1_RS00355 ^@ http://purl.uniprot.org/uniprot/F4LRM0 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/1209989:TEPRE1_RS05445 ^@ http://purl.uniprot.org/uniprot/F4LSH6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1209989:TEPRE1_RS10945 ^@ http://purl.uniprot.org/uniprot/F4LRX7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS06950 ^@ http://purl.uniprot.org/uniprot/F4LV08 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1209989:TEPRE1_RS01540 ^@ http://purl.uniprot.org/uniprot/F4LTH9 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1209989:TEPRE1_RS07545 ^@ http://purl.uniprot.org/uniprot/F4LVY4 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1209989:TEPRE1_RS01035 ^@ http://purl.uniprot.org/uniprot/F4LSV4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1209989:TEPRE1_RS05980 ^@ http://purl.uniprot.org/uniprot/F4LTL4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1209989:TEPRE1_RS11710 ^@ http://purl.uniprot.org/uniprot/F4LT61 ^@ Similarity|||Subunit ^@ Belongs to the beta-eliminating lyase family.|||Homotetramer. http://togogenome.org/gene/1209989:TEPRE1_RS06160 ^@ http://purl.uniprot.org/uniprot/F4LTQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07830 ^@ http://purl.uniprot.org/uniprot/F4LWA9 ^@ Similarity ^@ Belongs to the hexokinase family. http://togogenome.org/gene/1209989:TEPRE1_RS04150 ^@ http://purl.uniprot.org/uniprot/F4LX23 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS09400 ^@ http://purl.uniprot.org/uniprot/F4LQL2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1209989:TEPRE1_RS09205 ^@ http://purl.uniprot.org/uniprot/F4LXP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS12295 ^@ http://purl.uniprot.org/uniprot/F4LTW6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1209989:TEPRE1_RS12665 ^@ http://purl.uniprot.org/uniprot/F4LUI9 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS12810 ^@ http://purl.uniprot.org/uniprot/F4LUL9 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1209989:TEPRE1_RS05365 ^@ http://purl.uniprot.org/uniprot/F4LSG0 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1209989:TEPRE1_RS03930 ^@ http://purl.uniprot.org/uniprot/F4LWY1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS12320 ^@ http://purl.uniprot.org/uniprot/F4LTX1 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1209989:TEPRE1_RS03585 ^@ http://purl.uniprot.org/uniprot/F4LWI8 ^@ Function|||Similarity ^@ Belongs to the RapZ-like family.|||Displays ATPase and GTPase activities. http://togogenome.org/gene/1209989:TEPRE1_RS07815 ^@ http://purl.uniprot.org/uniprot/F4LWA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1209989:TEPRE1_RS09675 ^@ http://purl.uniprot.org/uniprot/F4LQR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1209989:TEPRE1_RS10455 ^@ http://purl.uniprot.org/uniprot/F4LR72 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1209989:TEPRE1_RS13175 ^@ http://purl.uniprot.org/uniprot/F4LV89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11995 ^@ http://purl.uniprot.org/uniprot/F4LTA4 ^@ Function|||Similarity ^@ Belongs to the 'phage' integrase family.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1209989:TEPRE1_RS10450 ^@ http://purl.uniprot.org/uniprot/F4LR71 ^@ Similarity ^@ Belongs to the UPF0065 (bug) family. http://togogenome.org/gene/1209989:TEPRE1_RS05150 ^@ http://purl.uniprot.org/uniprot/F4LSB8 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS07680 ^@ http://purl.uniprot.org/uniprot/F4LW13 ^@ Similarity ^@ Belongs to the transpeptidase family. http://togogenome.org/gene/1209989:TEPRE1_RS12590 ^@ http://purl.uniprot.org/uniprot/F4LUH5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS12585 ^@ http://purl.uniprot.org/uniprot/F4LUH4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/1209989:TEPRE1_RS07770 ^@ http://purl.uniprot.org/uniprot/F4LW27 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1209989:TEPRE1_RS00805 ^@ http://purl.uniprot.org/uniprot/F4LSA8 ^@ Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers). http://togogenome.org/gene/1209989:TEPRE1_RS01020 ^@ http://purl.uniprot.org/uniprot/F4LSV1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1209989:TEPRE1_RS09880 ^@ http://purl.uniprot.org/uniprot/F4LQV7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS10735 ^@ http://purl.uniprot.org/uniprot/F4LRE2 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 130 family. http://togogenome.org/gene/1209989:TEPRE1_RS05630 ^@ http://purl.uniprot.org/uniprot/F4LT10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00375 ^@ http://purl.uniprot.org/uniprot/F4LRM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1209989:TEPRE1_RS01485 ^@ http://purl.uniprot.org/uniprot/F4LTG8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS03070 ^@ http://purl.uniprot.org/uniprot/F4LVU7 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1209989:TEPRE1_RS01015 ^@ http://purl.uniprot.org/uniprot/F4LSV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1209989:TEPRE1_RS12375 ^@ http://purl.uniprot.org/uniprot/F4LTY1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer. http://togogenome.org/gene/1209989:TEPRE1_RS02575 ^@ http://purl.uniprot.org/uniprot/F4LVD7 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1209989:TEPRE1_RS08055 ^@ http://purl.uniprot.org/uniprot/F4LWF4 ^@ Similarity ^@ Belongs to the zinc-associated anti-sigma factor (ZAS) superfamily. Anti-sigma-W factor family. http://togogenome.org/gene/1209989:TEPRE1_RS07395 ^@ http://purl.uniprot.org/uniprot/F4LVN7 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1209989:TEPRE1_RS09260 ^@ http://purl.uniprot.org/uniprot/L0S0M7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS01305 ^@ http://purl.uniprot.org/uniprot/F4LTD5 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1209989:TEPRE1_RS09125 ^@ http://purl.uniprot.org/uniprot/F4LXN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06895 ^@ http://purl.uniprot.org/uniprot/F4LUZ7 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS12265 ^@ http://purl.uniprot.org/uniprot/F4LTW0 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1209989:TEPRE1_RS01970 ^@ http://purl.uniprot.org/uniprot/F4LUM5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1209989:TEPRE1_RS04910 ^@ http://purl.uniprot.org/uniprot/F4LRR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1209989:TEPRE1_RS02360 ^@ http://purl.uniprot.org/uniprot/F4LV95 ^@ Function ^@ May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. http://togogenome.org/gene/1209989:TEPRE1_RS03360 ^@ http://purl.uniprot.org/uniprot/F4LW74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1209989:TEPRE1_RS07220 ^@ http://purl.uniprot.org/uniprot/F4LVK2 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1209989:TEPRE1_RS03075 ^@ http://purl.uniprot.org/uniprot/F4LVU8 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1209989:TEPRE1_RS08155 ^@ http://purl.uniprot.org/uniprot/F4LWH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS07370 ^@ http://purl.uniprot.org/uniprot/F4LVN2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1209989:TEPRE1_RS09405 ^@ http://purl.uniprot.org/uniprot/F4LQL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FNT transporter (TC 2.A.44) family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06235 ^@ http://purl.uniprot.org/uniprot/F4LTR5 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1209989:TEPRE1_RS10340 ^@ http://purl.uniprot.org/uniprot/F4LR49 ^@ Function|||Similarity ^@ Belongs to the ATPase alpha/beta chains family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit. http://togogenome.org/gene/1209989:TEPRE1_RS03440 ^@ http://purl.uniprot.org/uniprot/F4LW83 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1209989:TEPRE1_RS09330 ^@ http://purl.uniprot.org/uniprot/F4LQJ7 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1209989:TEPRE1_RS10370 ^@ http://purl.uniprot.org/uniprot/F4LR55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase 116 kDa subunit family.|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS11355 ^@ http://purl.uniprot.org/uniprot/F4LSK8 ^@ Similarity ^@ Belongs to the PrpF family. http://togogenome.org/gene/1209989:TEPRE1_RS12460 ^@ http://purl.uniprot.org/uniprot/F4LUE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1209989:TEPRE1_RS00845 ^@ http://purl.uniprot.org/uniprot/F4LSR6 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.|||Binds 1 Mn(2+) ion per subunit.|||Cytoplasm|||Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1209989:TEPRE1_RS12690 ^@ http://purl.uniprot.org/uniprot/F4LUJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1209989:TEPRE1_RS06850 ^@ http://purl.uniprot.org/uniprot/F4LUY7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1209989:TEPRE1_RS08525 ^@ http://purl.uniprot.org/uniprot/F4LWW9 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1209989:TEPRE1_RS06280 ^@ http://purl.uniprot.org/uniprot/F4LU74 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.