http://togogenome.org/gene/1198449:ACAM_RS01715 ^@ http://purl.uniprot.org/uniprot/U3TBK8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.|||Belongs to the Holliday junction resolvase Hjc family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer. http://togogenome.org/gene/1198449:ACAM_RS01995 ^@ http://purl.uniprot.org/uniprot/U3TBR1 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1B family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1198449:ACAM_RS05785 ^@ http://purl.uniprot.org/uniprot/U3TH27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS04620 ^@ http://purl.uniprot.org/uniprot/U3TGC7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL15 family. http://togogenome.org/gene/1198449:ACAM_RS05915 ^@ http://purl.uniprot.org/uniprot/U3TAV4 ^@ Function|||Similarity ^@ Belongs to the TBP family.|||General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. http://togogenome.org/gene/1198449:ACAM_RS00315 ^@ http://purl.uniprot.org/uniprot/U3T7P0 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1198449:ACAM_RS05075 ^@ http://purl.uniprot.org/uniprot/U3TDG5 ^@ Function|||Similarity ^@ Belongs to the AdoMet synthase 2 family.|||Catalyzes the formation of S-adenosylmethionine from methionine and ATP. http://togogenome.org/gene/1198449:ACAM_RS07195 ^@ http://purl.uniprot.org/uniprot/U3TBG8 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1198449:ACAM_RS03660 ^@ http://purl.uniprot.org/uniprot/U3TDT9 ^@ Similarity ^@ Belongs to the UPF0173 family. http://togogenome.org/gene/1198449:ACAM_RS05980 ^@ http://purl.uniprot.org/uniprot/U3TH58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05790 ^@ http://purl.uniprot.org/uniprot/U3TF29 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS00250 ^@ http://purl.uniprot.org/uniprot/U3TDT3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS00220 ^@ http://purl.uniprot.org/uniprot/U3TC39 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1198449:ACAM_RS02550 ^@ http://purl.uniprot.org/uniprot/U3TC11 ^@ Similarity ^@ Belongs to the LDH/MDH superfamily. http://togogenome.org/gene/1198449:ACAM_RS07820 ^@ http://purl.uniprot.org/uniprot/U3TEY1 ^@ Function ^@ Part of a potassium transport system. http://togogenome.org/gene/1198449:ACAM_RS01485 ^@ http://purl.uniprot.org/uniprot/U3TEL5 ^@ Function|||Similarity ^@ Belongs to the V-ATPase E subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1198449:ACAM_RS02890 ^@ http://purl.uniprot.org/uniprot/U3TC69 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methyltransferase superfamily. TrmY family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs. http://togogenome.org/gene/1198449:ACAM_RS00300 ^@ http://purl.uniprot.org/uniprot/U3TDU1 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Heterooctamer of four alpha and four beta chains arranged as a tetramer of alpha/beta heterodimers.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity. http://togogenome.org/gene/1198449:ACAM_RS06450 ^@ http://purl.uniprot.org/uniprot/U3TB31 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1198449:ACAM_RS08020 ^@ http://purl.uniprot.org/uniprot/U3TBY6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05025 ^@ http://purl.uniprot.org/uniprot/U3TAA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS06985 ^@ http://purl.uniprot.org/uniprot/U3TEH3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.|||Binds 3 Mg(2+) cations per subunit. The strongest magnesium site (Mg1) is bound to the beta- and gamma-phosphates of ATP and four water molecules complete its coordination sphere.|||Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS03625 ^@ http://purl.uniprot.org/uniprot/U3TDZ7 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the C5 position of cytosine 72 in several tRNAs. http://togogenome.org/gene/1198449:ACAM_RS06400 ^@ http://purl.uniprot.org/uniprot/U3TB22 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates.|||Belongs to the AAA ATPase family.|||Consists of three main regions, an N-terminal coiled-coil domain that may assist in substrate recognition, an interdomain involved in PAN hexamerization, and a C-terminal ATPase domain of the AAA type.|||Cytoplasm|||Homohexamer. The hexameric complex has a two-ring architecture resembling a top hat that caps the 20S proteasome core at one or both ends. Upon ATP-binding, the C-terminus of PAN interacts with the alpha-rings of the proteasome core by binding to the intersubunit pockets. http://togogenome.org/gene/1198449:ACAM_RS05515 ^@ http://purl.uniprot.org/uniprot/U3TEV0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1198449:ACAM_RS06630 ^@ http://purl.uniprot.org/uniprot/U3TB59 ^@ Similarity ^@ Belongs to the UPF0107 family. http://togogenome.org/gene/1198449:ACAM_RS00980 ^@ http://purl.uniprot.org/uniprot/U3TEB9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the archaeal Spt4 family.|||Heterodimer composed of Spt4 and Spt5.|||Stimulates transcription elongation. http://togogenome.org/gene/1198449:ACAM_RS05705 ^@ http://purl.uniprot.org/uniprot/U3TGY9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic release factor 1 family. Pelota subfamily.|||Cytoplasm|||May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.|||Monomer.|||The N-terminal domain has the RNA-binding Sm fold. It harbors the endoribonuclease activity. http://togogenome.org/gene/1198449:ACAM_RS05875 ^@ http://purl.uniprot.org/uniprot/U3TF40 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NusA family.|||Cytoplasm|||Participates in transcription termination. http://togogenome.org/gene/1198449:ACAM_RS00865 ^@ http://purl.uniprot.org/uniprot/U3T818 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS07965 ^@ http://purl.uniprot.org/uniprot/U3TF04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0056 (MarC) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1198449:ACAM_RS06335 ^@ http://purl.uniprot.org/uniprot/U3TFA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS04415 ^@ http://purl.uniprot.org/uniprot/U3TEF4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS04380 ^@ http://purl.uniprot.org/uniprot/U3TD31 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS00430 ^@ http://purl.uniprot.org/uniprot/U3TAV3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL40 family. http://togogenome.org/gene/1198449:ACAM_RS02065 ^@ http://purl.uniprot.org/uniprot/U3TCW1 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1198449:ACAM_RS01305 ^@ http://purl.uniprot.org/uniprot/U3T882 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1198449:ACAM_RS00730 ^@ http://purl.uniprot.org/uniprot/U3TB36 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. Hel308 subfamily.|||DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.|||Monomer. http://togogenome.org/gene/1198449:ACAM_RS02060 ^@ http://purl.uniprot.org/uniprot/U3TEW6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the eukaryotic ribosomal protein eL37 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. http://togogenome.org/gene/1198449:ACAM_RS04685 ^@ http://purl.uniprot.org/uniprot/U3TA37 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS03995 ^@ http://purl.uniprot.org/uniprot/U3TDZ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1198449:ACAM_RS03220 ^@ http://purl.uniprot.org/uniprot/U3TCD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NucS endonuclease family.|||Cleaves both 3' and 5' ssDNA extremities of branched DNA structures.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS06535 ^@ http://purl.uniprot.org/uniprot/U3TB42 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. Homoserine kinase subfamily.|||Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS04855 ^@ http://purl.uniprot.org/uniprot/U3TEG9 ^@ Similarity ^@ Belongs to the FUN14 family. http://togogenome.org/gene/1198449:ACAM_RS00630 ^@ http://purl.uniprot.org/uniprot/U3T7V0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/1198449:ACAM_RS05635 ^@ http://purl.uniprot.org/uniprot/U3TEX8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ 2 residues (Tyr-66 and Arg-69) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.|||Belongs to the sirtuin family. Class III subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription. http://togogenome.org/gene/1198449:ACAM_RS05295 ^@ http://purl.uniprot.org/uniprot/U3TEQ7 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1198449:ACAM_RS01090 ^@ http://purl.uniprot.org/uniprot/U3TCK4 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1198449:ACAM_RS08175 ^@ http://purl.uniprot.org/uniprot/U3TF43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS01625 ^@ http://purl.uniprot.org/uniprot/U3TCU4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/1198449:ACAM_RS06695 ^@ http://purl.uniprot.org/uniprot/U3TFH3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1198449:ACAM_RS00785 ^@ http://purl.uniprot.org/uniprot/U3TB48 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/1198449:ACAM_RS06610 ^@ http://purl.uniprot.org/uniprot/U3TFL1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the eIF-5A family.|||Cytoplasm|||Functions by promoting the formation of the first peptide bond. http://togogenome.org/gene/1198449:ACAM_RS04860 ^@ http://purl.uniprot.org/uniprot/U3TDC7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the methylthiotransferase family. CDKAL1 subfamily.|||Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1198449:ACAM_RS02495 ^@ http://purl.uniprot.org/uniprot/U3T8V6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.|||Belongs to the TiaS family.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS02770 ^@ http://purl.uniprot.org/uniprot/U3T908 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS04645 ^@ http://purl.uniprot.org/uniprot/U3TGD2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. LysZ subfamily.|||Cytoplasm|||Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis). http://togogenome.org/gene/1198449:ACAM_RS01235 ^@ http://purl.uniprot.org/uniprot/U3TCM9 ^@ Similarity ^@ Belongs to the RuvB family. http://togogenome.org/gene/1198449:ACAM_RS07755 ^@ http://purl.uniprot.org/uniprot/U3TG73 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS04780 ^@ http://purl.uniprot.org/uniprot/U3TEF2 ^@ Similarity ^@ Belongs to the UPF0273 family. http://togogenome.org/gene/1198449:ACAM_RS05055 ^@ http://purl.uniprot.org/uniprot/U3TES6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS03510 ^@ http://purl.uniprot.org/uniprot/U3TFS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS07905 ^@ http://purl.uniprot.org/uniprot/U3TI42 ^@ Function|||Similarity ^@ Belongs to the EF-1-beta/EF-1-delta family.|||Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. http://togogenome.org/gene/1198449:ACAM_RS05855 ^@ http://purl.uniprot.org/uniprot/U3TDY8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1198449:ACAM_RS05400 ^@ http://purl.uniprot.org/uniprot/U3TDL7 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1198449:ACAM_RS07775 ^@ http://purl.uniprot.org/uniprot/U3TBT4 ^@ Caution|||Function|||Similarity ^@ Belongs to the TFIIB family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). http://togogenome.org/gene/1198449:ACAM_RS05885 ^@ http://purl.uniprot.org/uniprot/U3TAU9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms part of the jaw domain.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS02740 ^@ http://purl.uniprot.org/uniprot/U3TC44 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1198449:ACAM_RS05550 ^@ http://purl.uniprot.org/uniprot/U3TAL1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.|||Binds 1 zinc ion.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS06900 ^@ http://purl.uniprot.org/uniprot/U3TEG0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1198449:ACAM_RS06680 ^@ http://purl.uniprot.org/uniprot/U3TB67 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1198449:ACAM_RS03690 ^@ http://purl.uniprot.org/uniprot/U3TCP7 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eS31 family.|||Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS02620 ^@ http://purl.uniprot.org/uniprot/U3TF64 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1198449:ACAM_RS07560 ^@ http://purl.uniprot.org/uniprot/U3TFZ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NDK family.|||Cytoplasm|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1198449:ACAM_RS05800 ^@ http://purl.uniprot.org/uniprot/U3TAT5 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GyaR subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1198449:ACAM_RS03315 ^@ http://purl.uniprot.org/uniprot/U3TFN4 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL34 family. http://togogenome.org/gene/1198449:ACAM_RS00555 ^@ http://purl.uniprot.org/uniprot/U3T7T5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS01165 ^@ http://purl.uniprot.org/uniprot/U3TCE4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1198449:ACAM_RS02420 ^@ http://purl.uniprot.org/uniprot/U3TD91 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1198449:ACAM_RS01350 ^@ http://purl.uniprot.org/uniprot/U3TBE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L24e, part of which may contact the 16S rRNA in 2 intersubunit bridges. http://togogenome.org/gene/1198449:ACAM_RS03975 ^@ http://purl.uniprot.org/uniprot/U3TCV1 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1198449:ACAM_RS04515 ^@ http://purl.uniprot.org/uniprot/U3TEH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS01300 ^@ http://purl.uniprot.org/uniprot/U3TBD0 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Part of the 30S ribosomal subunit. Contacts protein S4.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1198449:ACAM_RS05900 ^@ http://purl.uniprot.org/uniprot/U3TF44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS02600 ^@ http://purl.uniprot.org/uniprot/U3TD70 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1198449:ACAM_RS03170 ^@ http://purl.uniprot.org/uniprot/U3TCC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05565 ^@ http://purl.uniprot.org/uniprot/U3TEW1 ^@ Similarity ^@ Belongs to the UPF0200 family. http://togogenome.org/gene/1198449:ACAM_RS04690 ^@ http://purl.uniprot.org/uniprot/U3TEK8 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS01035 ^@ http://purl.uniprot.org/uniprot/U3TEC9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS02950 ^@ http://purl.uniprot.org/uniprot/U3TDJ4 ^@ Function|||Similarity ^@ Belongs to the TYW3 family.|||S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72. http://togogenome.org/gene/1198449:ACAM_RS00100 ^@ http://purl.uniprot.org/uniprot/U3TDQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS06385 ^@ http://purl.uniprot.org/uniprot/U3THC3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the aTrm56 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs. http://togogenome.org/gene/1198449:ACAM_RS06785 ^@ http://purl.uniprot.org/uniprot/U3TFP4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Forms a complex with TatC.|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. http://togogenome.org/gene/1198449:ACAM_RS01360 ^@ http://purl.uniprot.org/uniprot/U3TCP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 1 family.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/1198449:ACAM_RS00985 ^@ http://purl.uniprot.org/uniprot/U3TCB6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Forms 2 domains with an elongated structure; Rpo4 packs into the hinge region between the 2 domains.|||Nucleus|||Part of the RNA polymerase complex. Forms a stalk with Rpo4 that extends from the main structure. http://togogenome.org/gene/1198449:ACAM_RS06860 ^@ http://purl.uniprot.org/uniprot/U3TFQ9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1198449:ACAM_RS00180 ^@ http://purl.uniprot.org/uniprot/U3TBT2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1198449:ACAM_RS01310 ^@ http://purl.uniprot.org/uniprot/U3TCN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL19 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS01340 ^@ http://purl.uniprot.org/uniprot/U3TEI6 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS4 family. http://togogenome.org/gene/1198449:ACAM_RS04605 ^@ http://purl.uniprot.org/uniprot/U3TD76 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase T1A family.|||Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.|||Cytoplasm|||The 20S proteasome core is composed of 14 alpha and 14 beta subunits that assemble into four stacked heptameric rings, resulting in a barrel-shaped structure. The two inner rings, each composed of seven catalytic beta subunits, are sandwiched by two outer rings, each composed of seven alpha subunits. The catalytic chamber with the active sites is on the inside of the barrel. Has a gated structure, the ends of the cylinder being occluded by the N-termini of the alpha-subunits. Is capped at one or both ends by the proteasome regulatory ATPase, PAN.|||The formation of the proteasomal ATPase PAN-20S proteasome complex, via the docking of the C-termini of PAN into the intersubunit pockets in the alpha-rings, triggers opening of the gate for substrate entry. Interconversion between the open-gate and close-gate conformations leads to a dynamic regulation of the 20S proteasome proteolysis activity. http://togogenome.org/gene/1198449:ACAM_RS07570 ^@ http://purl.uniprot.org/uniprot/U3TBP7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL24 family.|||Binds 1 zinc ion per subunit.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L14. http://togogenome.org/gene/1198449:ACAM_RS05230 ^@ http://purl.uniprot.org/uniprot/U3TAE3 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS01205 ^@ http://purl.uniprot.org/uniprot/U3TCM5 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1198449:ACAM_RS02575 ^@ http://purl.uniprot.org/uniprot/U3TC16 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1198449:ACAM_RS05200 ^@ http://purl.uniprot.org/uniprot/U3TDI7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS04530 ^@ http://purl.uniprot.org/uniprot/U3TD62 ^@ Similarity ^@ Belongs to the complex I 20 kDa subunit family. http://togogenome.org/gene/1198449:ACAM_RS01375 ^@ http://purl.uniprot.org/uniprot/U3TBE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1198449:ACAM_RS06140 ^@ http://purl.uniprot.org/uniprot/U3TF76 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the archaeal phosphopantothenate synthetase family.|||Catalyzes the condensation of (R)-4-phosphopantoate and beta-alanine to 4'-phosphopantothenate in the CoA biosynthesis pathway.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS03595 ^@ http://purl.uniprot.org/uniprot/U3T9I7 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL39 family. http://togogenome.org/gene/1198449:ACAM_RS00755 ^@ http://purl.uniprot.org/uniprot/U3TB46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS02030 ^@ http://purl.uniprot.org/uniprot/U3TD19 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1198449:ACAM_RS07490 ^@ http://purl.uniprot.org/uniprot/U3TER9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS01855 ^@ http://purl.uniprot.org/uniprot/U3TCR7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1198449:ACAM_RS01470 ^@ http://purl.uniprot.org/uniprot/U3TBG4 ^@ Function|||Similarity ^@ Belongs to the V-ATPase D subunit family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1198449:ACAM_RS06185 ^@ http://purl.uniprot.org/uniprot/U3TH90 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1198449:ACAM_RS07705 ^@ http://purl.uniprot.org/uniprot/U3TG63 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1198449:ACAM_RS00560 ^@ http://purl.uniprot.org/uniprot/U3TCA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M54 family.|||Binds 2 Zn(2+) ions per subunit. One is catalytic, whereas the other seems to have a structural role.|||Monomer.|||Probable zinc metalloprotease whose natural substrate is unknown. http://togogenome.org/gene/1198449:ACAM_RS08295 ^@ http://purl.uniprot.org/uniprot/U3TIE5 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1198449:ACAM_RS06895 ^@ http://purl.uniprot.org/uniprot/U3TFL3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein P1/P2 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the 50S ribosomal subunit. Homodimer, it forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Forms a heptameric L10(L12)2(L12)2(L12)2 complex, where L10 forms an elongated spine to which the L12 dimers bind in a sequential fashion. http://togogenome.org/gene/1198449:ACAM_RS07520 ^@ http://purl.uniprot.org/uniprot/U3TBN6 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1198449:ACAM_RS00135 ^@ http://purl.uniprot.org/uniprot/U3TAP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS06875 ^@ http://purl.uniprot.org/uniprot/U3TEF6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS04560 ^@ http://purl.uniprot.org/uniprot/U3TA14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prefoldin subunit beta family.|||Cytoplasm|||Heterohexamer of two alpha and four beta subunits.|||Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. http://togogenome.org/gene/1198449:ACAM_RS01645 ^@ http://purl.uniprot.org/uniprot/U3T8D5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS03615 ^@ http://purl.uniprot.org/uniprot/U3TCN6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic/archaeal RNase P protein component 4 family.|||Binds 1 zinc ion per subunit.|||Consists of a catalytic RNA component and at least 4-5 protein subunits.|||Cytoplasm|||Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. http://togogenome.org/gene/1198449:ACAM_RS07790 ^@ http://purl.uniprot.org/uniprot/U3TG38 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS04585 ^@ http://purl.uniprot.org/uniprot/U3TA19 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily.|||Binds to the 23S rRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS05030 ^@ http://purl.uniprot.org/uniprot/U3TES2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS03745 ^@ http://purl.uniprot.org/uniprot/U3T9K9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS1 family. http://togogenome.org/gene/1198449:ACAM_RS07240 ^@ http://purl.uniprot.org/uniprot/U3TFS6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. Prx6 subfamily.|||Cytoplasm|||Homodecamer. Pentamer of dimers that assemble into a ring structure.|||The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1198449:ACAM_RS02510 ^@ http://purl.uniprot.org/uniprot/U3TD54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS00030 ^@ http://purl.uniprot.org/uniprot/U3TBP8 ^@ Similarity ^@ Belongs to the DeoC/FbaB aldolase family. http://togogenome.org/gene/1198449:ACAM_RS07340 ^@ http://purl.uniprot.org/uniprot/U3THT4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase IV family.|||Binds 1 Fe(2+) ion per subunit.|||Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.|||Homodimer. http://togogenome.org/gene/1198449:ACAM_RS05310 ^@ http://purl.uniprot.org/uniprot/U3TEX4 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS05745 ^@ http://purl.uniprot.org/uniprot/U3TDV5 ^@ Similarity ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. http://togogenome.org/gene/1198449:ACAM_RS00185 ^@ http://purl.uniprot.org/uniprot/U3TAQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1198449:ACAM_RS05870 ^@ http://purl.uniprot.org/uniprot/U3TH40 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Part of the 30S ribosomal subunit.|||With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. http://togogenome.org/gene/1198449:ACAM_RS06790 ^@ http://purl.uniprot.org/uniprot/U3THJ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamine synthetase family.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS00705 ^@ http://purl.uniprot.org/uniprot/U3TB30 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1198449:ACAM_RS00570 ^@ http://purl.uniprot.org/uniprot/U3TC20 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1198449:ACAM_RS05950 ^@ http://purl.uniprot.org/uniprot/U3TF99 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1198449:ACAM_RS01295 ^@ http://purl.uniprot.org/uniprot/U3TCG4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS04865 ^@ http://purl.uniprot.org/uniprot/U3TA73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the eIF-2-beta/eIF-5 family.|||Heterotrimer composed of an alpha, a beta and a gamma chain.|||eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. http://togogenome.org/gene/1198449:ACAM_RS01395 ^@ http://purl.uniprot.org/uniprot/U3TCI3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/1198449:ACAM_RS06675 ^@ http://purl.uniprot.org/uniprot/U3TEB8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS07900 ^@ http://purl.uniprot.org/uniprot/U3TBW2 ^@ Similarity ^@ Belongs to the AAA ATPase family. CDC48 subfamily. http://togogenome.org/gene/1198449:ACAM_RS03525 ^@ http://purl.uniprot.org/uniprot/U3T9H5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TYW1 family.|||Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1198449:ACAM_RS03490 ^@ http://purl.uniprot.org/uniprot/U3TDR5 ^@ Similarity ^@ Belongs to the flavin oxidoreductase frp family. http://togogenome.org/gene/1198449:ACAM_RS05825 ^@ http://purl.uniprot.org/uniprot/U3TAT7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1198449:ACAM_RS01495 ^@ http://purl.uniprot.org/uniprot/U3TBH1 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1198449:ACAM_RS05595 ^@ http://purl.uniprot.org/uniprot/U3TDR0 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1198449:ACAM_RS06405 ^@ http://purl.uniprot.org/uniprot/U3TFH7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo8 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS01670 ^@ http://purl.uniprot.org/uniprot/U3T8E2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL16 family. http://togogenome.org/gene/1198449:ACAM_RS02895 ^@ http://purl.uniprot.org/uniprot/U3T934 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS04500 ^@ http://purl.uniprot.org/uniprot/U3TE94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS02870 ^@ http://purl.uniprot.org/uniprot/U3T929 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS04660 ^@ http://purl.uniprot.org/uniprot/U3TA32 ^@ Similarity ^@ Belongs to the RimK family. LysX subfamily. http://togogenome.org/gene/1198449:ACAM_RS04675 ^@ http://purl.uniprot.org/uniprot/U3TED1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1198449:ACAM_RS06035 ^@ http://purl.uniprot.org/uniprot/U3TH66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1198449:ACAM_RS07455 ^@ http://purl.uniprot.org/uniprot/U3THV7 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/1198449:ACAM_RS06995 ^@ http://purl.uniprot.org/uniprot/U3TFT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the methyltransferase superfamily. Fibrillarin family.|||Interacts with nop5. Component of box C/D small ribonucleoprotein (sRNP) particles that contain rpl7ae, FlpA and nop5, plus a guide RNA.|||Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. http://togogenome.org/gene/1198449:ACAM_RS03545 ^@ http://purl.uniprot.org/uniprot/U3T9H9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1198449:ACAM_RS04815 ^@ http://purl.uniprot.org/uniprot/U3TA63 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1198449:ACAM_RS03815 ^@ http://purl.uniprot.org/uniprot/U3TFY2 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1198449:ACAM_RS03000 ^@ http://purl.uniprot.org/uniprot/U3T953 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS03710 ^@ http://purl.uniprot.org/uniprot/U3TDU6 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS07015 ^@ http://purl.uniprot.org/uniprot/U3TBD2 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate.|||Belongs to the GatB/GatE family. GatE subfamily.|||Heterodimer of GatD and GatE. http://togogenome.org/gene/1198449:ACAM_RS06920 ^@ http://purl.uniprot.org/uniprot/U3TFL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY (alpha), SecG (beta) and SecE (gamma) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS04670 ^@ http://purl.uniprot.org/uniprot/U3TGD7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M20A family. LysK subfamily.|||Binds 2 Zn(2+) or Co(2+) ions per subunit.|||Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine and the release of L-ornithine from [LysW]-L-ornithine.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS04760 ^@ http://purl.uniprot.org/uniprot/U3TDA8 ^@ Similarity ^@ Belongs to the Ahb/Nir family. http://togogenome.org/gene/1198449:ACAM_RS06700 ^@ http://purl.uniprot.org/uniprot/U3TEC3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the archaeal riboflavin kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS05560 ^@ http://purl.uniprot.org/uniprot/U3TGV4 ^@ Similarity ^@ Belongs to the UPF0201 family. http://togogenome.org/gene/1198449:ACAM_RS00385 ^@ http://purl.uniprot.org/uniprot/U3T7Q4 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1198449:ACAM_RS01325 ^@ http://purl.uniprot.org/uniprot/U3TBD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS03335 ^@ http://purl.uniprot.org/uniprot/U3TDU4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. May interact with SecDF, and other proteins may be involved.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1198449:ACAM_RS03770 ^@ http://purl.uniprot.org/uniprot/U3T9L2 ^@ Similarity ^@ Belongs to the SDO1/SBDS family. http://togogenome.org/gene/1198449:ACAM_RS06760 ^@ http://purl.uniprot.org/uniprot/U3TFN8 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1198449:ACAM_RS00900 ^@ http://purl.uniprot.org/uniprot/U3TEA7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1198449:ACAM_RS02160 ^@ http://purl.uniprot.org/uniprot/U3T8N7 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. http://togogenome.org/gene/1198449:ACAM_RS01990 ^@ http://purl.uniprot.org/uniprot/U3TCU3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1198449:ACAM_RS06635 ^@ http://purl.uniprot.org/uniprot/U3TFL5 ^@ Caution|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS07135 ^@ http://purl.uniprot.org/uniprot/U3TFQ6 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1198449:ACAM_RS03275 ^@ http://purl.uniprot.org/uniprot/U3TCG2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS07410 ^@ http://purl.uniprot.org/uniprot/U3TG05 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the V-ATPase proteolipid subunit family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS01730 ^@ http://purl.uniprot.org/uniprot/U3TEQ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ThiI family.|||Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS00720 ^@ http://purl.uniprot.org/uniprot/U3TE70 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1198449:ACAM_RS03240 ^@ http://purl.uniprot.org/uniprot/U3TFK0 ^@ Similarity ^@ Belongs to the AAA ATPase family. http://togogenome.org/gene/1198449:ACAM_RS02135 ^@ http://purl.uniprot.org/uniprot/U3T8N2 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/1198449:ACAM_RS03305 ^@ http://purl.uniprot.org/uniprot/U3T9D8 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL14 family. http://togogenome.org/gene/1198449:ACAM_RS07735 ^@ http://purl.uniprot.org/uniprot/U3TI08 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1198449:ACAM_RS03580 ^@ http://purl.uniprot.org/uniprot/U3TFT7 ^@ Similarity|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL20 family.|||Part of the 50S ribosomal subunit. Binds 23S rRNA. http://togogenome.org/gene/1198449:ACAM_RS06005 ^@ http://purl.uniprot.org/uniprot/U3TFA7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1198449:ACAM_RS05420 ^@ http://purl.uniprot.org/uniprot/U3TET1 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1198449:ACAM_RS03600 ^@ http://purl.uniprot.org/uniprot/U3TDZ1 ^@ Similarity ^@ Belongs to the PDCD5 family. http://togogenome.org/gene/1198449:ACAM_RS05535 ^@ http://purl.uniprot.org/uniprot/U3TGU9 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL18 family. http://togogenome.org/gene/1198449:ACAM_RS05485 ^@ http://purl.uniprot.org/uniprot/U3TGT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS03630 ^@ http://purl.uniprot.org/uniprot/U3TFU6 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1198449:ACAM_RS06145 ^@ http://purl.uniprot.org/uniprot/U3TE35 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. PoK subfamily.|||Phosphorylates (R)-pantoate to form (R)-4-phosphopantoate in the CoA biosynthesis pathway. http://togogenome.org/gene/1198449:ACAM_RS00025 ^@ http://purl.uniprot.org/uniprot/U3TDN3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS03550 ^@ http://purl.uniprot.org/uniprot/U3TDY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1198449:ACAM_RS07715 ^@ http://purl.uniprot.org/uniprot/U3TG23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the beta-RFA-P synthase family.|||Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).|||Homodimer. http://togogenome.org/gene/1198449:ACAM_RS05605 ^@ http://purl.uniprot.org/uniprot/U3TF30 ^@ Similarity ^@ Belongs to the isopentenyl phosphate kinase family. http://togogenome.org/gene/1198449:ACAM_RS03990 ^@ http://purl.uniprot.org/uniprot/U3TG15 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the CRISPR-associated exonuclease Cas4 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).|||Mg(2+) or Mn(2+) required for ssDNA cleavage activity. http://togogenome.org/gene/1198449:ACAM_RS06820 ^@ http://purl.uniprot.org/uniprot/U3TFJ7 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1198449:ACAM_RS02735 ^@ http://purl.uniprot.org/uniprot/U3TD99 ^@ Function|||Similarity ^@ Belongs to the eIF-1A family.|||Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. http://togogenome.org/gene/1198449:ACAM_RS00940 ^@ http://purl.uniprot.org/uniprot/U3TB71 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glutaminase PdxT/SNO family.|||Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.|||In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer. http://togogenome.org/gene/1198449:ACAM_RS01785 ^@ http://purl.uniprot.org/uniprot/U3TBM2 ^@ Function ^@ CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1198449:ACAM_RS06180 ^@ http://purl.uniprot.org/uniprot/U3TFD7 ^@ Similarity ^@ Belongs to the ZPR1 family. http://togogenome.org/gene/1198449:ACAM_RS03075 ^@ http://purl.uniprot.org/uniprot/U3T967 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS00215 ^@ http://purl.uniprot.org/uniprot/U3T7L7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS01320 ^@ http://purl.uniprot.org/uniprot/U3TCG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1198449:ACAM_RS02915 ^@ http://purl.uniprot.org/uniprot/U3TC74 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the 'phage' integrase family. XerA subfamily.|||Cytoplasm|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. http://togogenome.org/gene/1198449:ACAM_RS04890 ^@ http://purl.uniprot.org/uniprot/U3TA79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TmcA family.|||Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||nucleolus http://togogenome.org/gene/1198449:ACAM_RS03830 ^@ http://purl.uniprot.org/uniprot/U3T9M3 ^@ Similarity ^@ Belongs to the sulfate adenylyltransferase family. http://togogenome.org/gene/1198449:ACAM_RS05455 ^@ http://purl.uniprot.org/uniprot/U3TF03 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1198449:ACAM_RS04665 ^@ http://purl.uniprot.org/uniprot/U3TEK3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||Involved in both the arginine and lysine biosynthetic pathways.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS05290 ^@ http://purl.uniprot.org/uniprot/U3TGP7 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1198449:ACAM_RS00115 ^@ http://purl.uniprot.org/uniprot/U3T7J5 ^@ Similarity ^@ Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. http://togogenome.org/gene/1198449:ACAM_RS00860 ^@ http://purl.uniprot.org/uniprot/U3TB60 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L24e. http://togogenome.org/gene/1198449:ACAM_RS02145 ^@ http://purl.uniprot.org/uniprot/U3TEY0 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL21 family. http://togogenome.org/gene/1198449:ACAM_RS04580 ^@ http://purl.uniprot.org/uniprot/U3TD71 ^@ Function ^@ Probably involved in the biogenesis of the ribosome. http://togogenome.org/gene/1198449:ACAM_RS06750 ^@ http://purl.uniprot.org/uniprot/U3TED2 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS03570 ^@ http://purl.uniprot.org/uniprot/U3T9I3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. http://togogenome.org/gene/1198449:ACAM_RS01330 ^@ http://purl.uniprot.org/uniprot/U3T887 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS06915 ^@ http://purl.uniprot.org/uniprot/U3THL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SPT5 family.|||Belongs to the archaeal Spt5 family.|||Heterodimer composed of Spt4 and Spt5. Interacts with RNA polymerase (RNAP).|||Stimulates transcription elongation. http://togogenome.org/gene/1198449:ACAM_RS03160 ^@ http://purl.uniprot.org/uniprot/U3TFI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS01755 ^@ http://purl.uniprot.org/uniprot/U3TCP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1198449:ACAM_RS01885 ^@ http://purl.uniprot.org/uniprot/U3TBP1 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS05365 ^@ http://purl.uniprot.org/uniprot/U3TGR3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05350 ^@ http://purl.uniprot.org/uniprot/U3TDL0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05580 ^@ http://purl.uniprot.org/uniprot/U3TF25 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/1198449:ACAM_RS04445 ^@ http://purl.uniprot.org/uniprot/U3TG96 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS08305 ^@ http://purl.uniprot.org/uniprot/U3TF98 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1198449:ACAM_RS03685 ^@ http://purl.uniprot.org/uniprot/U3TDU3 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS24 family. http://togogenome.org/gene/1198449:ACAM_RS05270 ^@ http://purl.uniprot.org/uniprot/U3TEQ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PTH2 family.|||Cytoplasm|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1198449:ACAM_RS06380 ^@ http://purl.uniprot.org/uniprot/U3TFH4 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the TFE family.|||Monomer. Interaction with RNA polymerase subunits RpoF and RpoE is necessary for Tfe stimulatory transcription activity. Able to interact with Tbp and RNA polymerase in the absence of DNA promoter. Interacts both with the preinitiation and elongation complexes.|||The winged helix domain is involved in binding to DNA in the preinitiation complex.|||Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes. http://togogenome.org/gene/1198449:ACAM_RS01050 ^@ http://purl.uniprot.org/uniprot/U3TB85 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the UPF0165 family. http://togogenome.org/gene/1198449:ACAM_RS05890 ^@ http://purl.uniprot.org/uniprot/U3TF91 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds at least 2 Zn(2+) per subunit.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Forms the clamp head domain.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS04710 ^@ http://purl.uniprot.org/uniprot/U3TA42 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DtdA deacylase family.|||Binds 2 Zn(2+) ions per subunit.|||D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo.|||Monomer. http://togogenome.org/gene/1198449:ACAM_RS05770 ^@ http://purl.uniprot.org/uniprot/U3TDX1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase may regulate its activity.|||Belongs to the histone-like Alba family.|||Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes.|||Chromosome|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1198449:ACAM_RS00605 ^@ http://purl.uniprot.org/uniprot/U3T7U5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS06945 ^@ http://purl.uniprot.org/uniprot/U3TFM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PCNA family.|||Homotrimer. The subunits circularize to form a toroid; DNA passes through its center. Replication factor C (RFC) is required to load the toroid on the DNA.|||Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. http://togogenome.org/gene/1198449:ACAM_RS05850 ^@ http://purl.uniprot.org/uniprot/U3TF37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1198449:ACAM_RS07510 ^@ http://purl.uniprot.org/uniprot/U3TFY5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS07940 ^@ http://purl.uniprot.org/uniprot/U3TF01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS01250 ^@ http://purl.uniprot.org/uniprot/U3TBC1 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the dCTP deaminase family.|||Catalyzes the deamination of dCTP to dUTP.|||Homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1198449:ACAM_RS07800 ^@ http://purl.uniprot.org/uniprot/U3TBU0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1198449:ACAM_RS01680 ^@ http://purl.uniprot.org/uniprot/U3TEP9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils.|||Belongs to the Cren7 family.|||Cytoplasm|||Methylated at multiple sites, to varying extents.|||Monomer. http://togogenome.org/gene/1198449:ACAM_RS05495 ^@ http://purl.uniprot.org/uniprot/U3TDN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS07550 ^@ http://purl.uniprot.org/uniprot/U3TG35 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eS6 family. http://togogenome.org/gene/1198449:ACAM_RS05305 ^@ http://purl.uniprot.org/uniprot/U3TAF6 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS05275 ^@ http://purl.uniprot.org/uniprot/U3TDJ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrI family.|||Binds 1 zinc ion per subunit.|||Contains catalytic and regulatory chains.|||Involved in allosteric regulation of aspartate carbamoyltransferase. http://togogenome.org/gene/1198449:ACAM_RS02235 ^@ http://purl.uniprot.org/uniprot/U3T8Q4 ^@ Subunit ^@ Heterodimer composed of an alpha and a beta subunit. http://togogenome.org/gene/1198449:ACAM_RS02880 ^@ http://purl.uniprot.org/uniprot/U3TFB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS03070 ^@ http://purl.uniprot.org/uniprot/U3TCA6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.|||Cytoplasm|||DNA-dependent RNA polymerase (RNAP) catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Part of the RNA polymerase complex. http://togogenome.org/gene/1198449:ACAM_RS06460 ^@ http://purl.uniprot.org/uniprot/U3TFI5 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1198449:ACAM_RS08210 ^@ http://purl.uniprot.org/uniprot/U3TC27 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS01490 ^@ http://purl.uniprot.org/uniprot/U3TCK2 ^@ Similarity ^@ Belongs to the V-ATPase F subunit family. http://togogenome.org/gene/1198449:ACAM_RS02485 ^@ http://purl.uniprot.org/uniprot/U3TD48 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SEC61-beta family.|||Cell membrane|||Component of the protein translocase complex. Heterotrimer consisting of alpha (SecY), beta (SecG) and gamma (SecE) subunits. Can form oligomers of the heterotrimer.|||Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS02995 ^@ http://purl.uniprot.org/uniprot/U3TC90 ^@ Similarity ^@ Belongs to the UPF0175 family. http://togogenome.org/gene/1198449:ACAM_RS07395 ^@ http://purl.uniprot.org/uniprot/U3TEQ2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL33 family. http://togogenome.org/gene/1198449:ACAM_RS06465 ^@ http://purl.uniprot.org/uniprot/U3THD6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the archaeal MetE family.|||Binds 1 zinc ion per subunit.|||Catalyzes the transfer of a methyl group to L-homocysteine resulting in methionine formation. The physiological methyl donor is unknown. http://togogenome.org/gene/1198449:ACAM_RS01590 ^@ http://purl.uniprot.org/uniprot/U3T8C6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-archaeol synthase family.|||Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids.|||Cell membrane http://togogenome.org/gene/1198449:ACAM_RS00050 ^@ http://purl.uniprot.org/uniprot/U3TDN9 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1198449:ACAM_RS04180 ^@ http://purl.uniprot.org/uniprot/U3TG51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS03155 ^@ http://purl.uniprot.org/uniprot/U3T980 ^@ Similarity ^@ Belongs to the UPF0248 family. http://togogenome.org/gene/1198449:ACAM_RS07695 ^@ http://purl.uniprot.org/uniprot/U3TEV8 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1198449:ACAM_RS00105 ^@ http://purl.uniprot.org/uniprot/U3TBR4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1198449:ACAM_RS04955 ^@ http://purl.uniprot.org/uniprot/U3TGH7 ^@ Function|||Similarity ^@ Belongs to the HARP family.|||RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. http://togogenome.org/gene/1198449:ACAM_RS07555 ^@ http://purl.uniprot.org/uniprot/U3THX6 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. http://togogenome.org/gene/1198449:ACAM_RS02865 ^@ http://purl.uniprot.org/uniprot/U3TC64 ^@ Similarity ^@ Belongs to the GPN-loop GTPase family. http://togogenome.org/gene/1198449:ACAM_RS03590 ^@ http://purl.uniprot.org/uniprot/U3TCN2 ^@ Similarity ^@ Belongs to the eukaryotic ribosomal protein eL31 family.|||Belongs to the ribosomal protein L31e family. http://togogenome.org/gene/1198449:ACAM_RS05000 ^@ http://purl.uniprot.org/uniprot/U3TER7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS00580 ^@ http://purl.uniprot.org/uniprot/U3T7U0 ^@ Similarity ^@ Belongs to the CDC6/cdc18 family. http://togogenome.org/gene/1198449:ACAM_RS04600 ^@ http://purl.uniprot.org/uniprot/U3TEB6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RRP4 family.|||Component of the archaeal exosome complex. Forms a trimer of Rrp4 and/or Csl4 subunits. The trimer associates with an hexameric ring-like arrangement composed of 3 Rrp41-Rrp42 heterodimers.|||Cytoplasm|||Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. http://togogenome.org/gene/1198449:ACAM_RS00565 ^@ http://purl.uniprot.org/uniprot/U3TE06 ^@ Function|||Similarity ^@ Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently.|||Belongs to the archease family. http://togogenome.org/gene/1198449:ACAM_RS05520 ^@ http://purl.uniprot.org/uniprot/U3TDP2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1198449:ACAM_RS03350 ^@ http://purl.uniprot.org/uniprot/U3TCI6 ^@ Similarity ^@ Belongs to the DMRL synthase family. http://togogenome.org/gene/1198449:ACAM_RS05135 ^@ http://purl.uniprot.org/uniprot/U3TEU2 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1198449:ACAM_RS04810 ^@ http://purl.uniprot.org/uniprot/U3TDB7 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1198449:ACAM_RS00410 ^@ http://purl.uniprot.org/uniprot/U3T7Q8 ^@ Similarity ^@ Belongs to the HerA family. http://togogenome.org/gene/1198449:ACAM_RS05755 ^@ http://purl.uniprot.org/uniprot/U3TF73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the eukaryotic ribosomal protein eL8 family.|||Cytoplasm|||Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs.|||Part of the 50S ribosomal subunit. Probably part of the RNase P complex. http://togogenome.org/gene/1198449:ACAM_RS06510 ^@ http://purl.uniprot.org/uniprot/U3TFJ6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1198449:ACAM_RS05300 ^@ http://purl.uniprot.org/uniprot/U3TDK4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1198449:ACAM_RS03330 ^@ http://purl.uniprot.org/uniprot/U3T9E3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the archaeal adenylate kinase family.|||Cytoplasm http://togogenome.org/gene/1198449:ACAM_RS06300 ^@ http://purl.uniprot.org/uniprot/U3TFG0 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1198449:ACAM_RS01970 ^@ http://purl.uniprot.org/uniprot/U3TBQ6 ^@ Similarity ^@ Belongs to the UPF0282 family. http://togogenome.org/gene/1198449:ACAM_RS05545 ^@ http://purl.uniprot.org/uniprot/U3TDP7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family.