http://togogenome.org/gene/1184267:A11Q_RS00770 ^@ http://purl.uniprot.org/uniprot/M4V4W2 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03615 ^@ http://purl.uniprot.org/uniprot/M4VA92 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11890 ^@ http://purl.uniprot.org/uniprot/M4VTQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1184267:A11Q_RS10710 ^@ http://purl.uniprot.org/uniprot/M4VAA8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02615 ^@ http://purl.uniprot.org/uniprot/M4VNQ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS05430 ^@ http://purl.uniprot.org/uniprot/M4VQ70 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1184267:A11Q_RS09640 ^@ http://purl.uniprot.org/uniprot/M4VA90 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1184267:A11Q_RS12890 ^@ http://purl.uniprot.org/uniprot/M4VFE7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS02550 ^@ http://purl.uniprot.org/uniprot/M4V9M6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS08590 ^@ http://purl.uniprot.org/uniprot/M4V943 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1184267:A11Q_RS06740 ^@ http://purl.uniprot.org/uniprot/M4VC10 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS06795 ^@ http://purl.uniprot.org/uniprot/M4V855 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1184267:A11Q_RS02395 ^@ http://purl.uniprot.org/uniprot/M4V9J6 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1184267:A11Q_RS01350 ^@ http://purl.uniprot.org/uniprot/M4V915 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS07755 ^@ http://purl.uniprot.org/uniprot/M4V8N3 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1184267:A11Q_RS11590 ^@ http://purl.uniprot.org/uniprot/M4VTK6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1184267:A11Q_RS07290 ^@ http://purl.uniprot.org/uniprot/M4V8E6 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1184267:A11Q_RS08915 ^@ http://purl.uniprot.org/uniprot/M4VS33 ^@ Similarity ^@ Belongs to the GPI family. http://togogenome.org/gene/1184267:A11Q_RS09650 ^@ http://purl.uniprot.org/uniprot/M4VCC5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1184267:A11Q_RS10845 ^@ http://purl.uniprot.org/uniprot/M4VT35 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09600 ^@ http://purl.uniprot.org/uniprot/M4VCB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1184267:A11Q_RS06900 ^@ http://purl.uniprot.org/uniprot/M4VQZ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS04055 ^@ http://purl.uniprot.org/uniprot/M4V756 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04580 ^@ http://purl.uniprot.org/uniprot/M4V7E7 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated Cas9 family.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.|||Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Binds crRNA and tracrRNA. http://togogenome.org/gene/1184267:A11Q_RS08440 ^@ http://purl.uniprot.org/uniprot/M4V9K3 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/1184267:A11Q_RS12435 ^@ http://purl.uniprot.org/uniprot/M4VTZ3 ^@ Similarity ^@ Belongs to the arylamine N-acetyltransferase family. http://togogenome.org/gene/1184267:A11Q_RS04605 ^@ http://purl.uniprot.org/uniprot/M4V7F2 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1184267:A11Q_RS00420 ^@ http://purl.uniprot.org/uniprot/M4V790 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS13060 ^@ http://purl.uniprot.org/uniprot/M4VFI2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS10285 ^@ http://purl.uniprot.org/uniprot/M4VA27 ^@ Similarity ^@ Belongs to the peptidase S13 family. http://togogenome.org/gene/1184267:A11Q_RS05185 ^@ http://purl.uniprot.org/uniprot/M4V9W4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the tryptophan 2,3-dioxygenase family.|||Binds 1 heme group per subunit.|||Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09520 ^@ http://purl.uniprot.org/uniprot/M4VSD5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS07115 ^@ http://purl.uniprot.org/uniprot/M4VR36 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1184267:A11Q_RS06670 ^@ http://purl.uniprot.org/uniprot/M4V834 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS09400 ^@ http://purl.uniprot.org/uniprot/M4VC81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS05665 ^@ http://purl.uniprot.org/uniprot/M4VA54 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1184267:A11Q_RS06730 ^@ http://purl.uniprot.org/uniprot/M4VQX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12755 ^@ http://purl.uniprot.org/uniprot/M4VU56 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1184267:A11Q_RS03035 ^@ http://purl.uniprot.org/uniprot/M4VNX2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS05440 ^@ http://purl.uniprot.org/uniprot/M4VB97 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1184267:A11Q_RS10685 ^@ http://purl.uniprot.org/uniprot/M4VAA2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS04270 ^@ http://purl.uniprot.org/uniprot/M4V6S5 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1184267:A11Q_RS09190 ^@ http://purl.uniprot.org/uniprot/M4VA19 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1184267:A11Q_RS00150 ^@ http://purl.uniprot.org/uniprot/M4V737 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1184267:A11Q_RS04715 ^@ http://purl.uniprot.org/uniprot/M4V9N4 ^@ Similarity ^@ Belongs to the peptidase C15 family. http://togogenome.org/gene/1184267:A11Q_RS09455 ^@ http://purl.uniprot.org/uniprot/M4VDI8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04945 ^@ http://purl.uniprot.org/uniprot/M4VB00 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YceF subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1184267:A11Q_RS08320 ^@ http://purl.uniprot.org/uniprot/M4VRQ9 ^@ Function|||Similarity ^@ Belongs to the aldehyde dehydrogenase family.|||In the C-terminal section; belongs to the aldehyde dehydrogenase family.|||In the N-terminal section; belongs to the proline dehydrogenase family.|||Oxidizes proline to glutamate for use as a carbon and nitrogen source. http://togogenome.org/gene/1184267:A11Q_RS11400 ^@ http://purl.uniprot.org/uniprot/M4VEN8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1184267:A11Q_RS04545 ^@ http://purl.uniprot.org/uniprot/M4VAS3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS04940 ^@ http://purl.uniprot.org/uniprot/M4V9S3 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1184267:A11Q_RS07930 ^@ http://purl.uniprot.org/uniprot/M4VCN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS04230 ^@ http://purl.uniprot.org/uniprot/M4V787 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS03925 ^@ http://purl.uniprot.org/uniprot/M4V6L7 ^@ Cofactor|||Function ^@ Accepts electrons from ETF and reduces ubiquinone.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1184267:A11Q_RS04655 ^@ http://purl.uniprot.org/uniprot/M4V7G1 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1184267:A11Q_RS05715 ^@ http://purl.uniprot.org/uniprot/M4VQC0 ^@ Function|||Similarity ^@ Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.|||Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids. http://togogenome.org/gene/1184267:A11Q_RS04420 ^@ http://purl.uniprot.org/uniprot/M4VAQ3 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1184267:A11Q_RS10255 ^@ http://purl.uniprot.org/uniprot/M4VDY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS03675 ^@ http://purl.uniprot.org/uniprot/M4V6X7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS09225 ^@ http://purl.uniprot.org/uniprot/M4VC52 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS09230 ^@ http://purl.uniprot.org/uniprot/M4VDE9 ^@ Similarity ^@ Belongs to the TOP6A family. http://togogenome.org/gene/1184267:A11Q_RS02775 ^@ http://purl.uniprot.org/uniprot/M4V9S2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS06190 ^@ http://purl.uniprot.org/uniprot/M4V8B0 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.|||Binds 2 Zn(2+) ions per subunit.|||Monomer.|||Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid. http://togogenome.org/gene/1184267:A11Q_RS11705 ^@ http://purl.uniprot.org/uniprot/M4VAY8 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1184267:A11Q_RS09830 ^@ http://purl.uniprot.org/uniprot/M4VDP9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS05655 ^@ http://purl.uniprot.org/uniprot/M4V7Z3 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1184267:A11Q_RS03765 ^@ http://purl.uniprot.org/uniprot/M4VAE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS10865 ^@ http://purl.uniprot.org/uniprot/M4VAX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS09030 ^@ http://purl.uniprot.org/uniprot/M4V9F5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS07325 ^@ http://purl.uniprot.org/uniprot/M4VB24 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. http://togogenome.org/gene/1184267:A11Q_RS01650 ^@ http://purl.uniprot.org/uniprot/M4V963 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1184267:A11Q_RS08235 ^@ http://purl.uniprot.org/uniprot/M4V8X6 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1184267:A11Q_RS02845 ^@ http://purl.uniprot.org/uniprot/M4V9T5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS12645 ^@ http://purl.uniprot.org/uniprot/M4VBF4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1184267:A11Q_RS13260 ^@ http://purl.uniprot.org/uniprot/M4VN58 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1184267:A11Q_RS05500 ^@ http://purl.uniprot.org/uniprot/M4V7W0 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the IcmF family.|||Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.|||Homodimer.|||Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS07050 ^@ http://purl.uniprot.org/uniprot/M4VC63 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1184267:A11Q_RS06880 ^@ http://purl.uniprot.org/uniprot/M4VAT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1184267:A11Q_RS05385 ^@ http://purl.uniprot.org/uniprot/M4VA02 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/1184267:A11Q_RS13130 ^@ http://purl.uniprot.org/uniprot/M4VEA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase delta chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1184267:A11Q_RS02315 ^@ http://purl.uniprot.org/uniprot/M4V8A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.|||Cytoplasm|||Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. http://togogenome.org/gene/1184267:A11Q_RS04175 ^@ http://purl.uniprot.org/uniprot/M4V6Q7 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS04710 ^@ http://purl.uniprot.org/uniprot/M4VPU3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS07590 ^@ http://purl.uniprot.org/uniprot/M4VRC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02630 ^@ http://purl.uniprot.org/uniprot/M4V5V8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS05705 ^@ http://purl.uniprot.org/uniprot/M4V7H9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1184267:A11Q_RS08360 ^@ http://purl.uniprot.org/uniprot/M4V8Z6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02780 ^@ http://purl.uniprot.org/uniprot/M4V6F0 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1184267:A11Q_RS09505 ^@ http://purl.uniprot.org/uniprot/M4VDJ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1184267:A11Q_RS10670 ^@ http://purl.uniprot.org/uniprot/M4VSZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS06315 ^@ http://purl.uniprot.org/uniprot/M4V8F9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1184267:A11Q_RS11425 ^@ http://purl.uniprot.org/uniprot/M4VEP2 ^@ Similarity ^@ Belongs to the HMG-CoA lyase family. http://togogenome.org/gene/1184267:A11Q_RS03610 ^@ http://purl.uniprot.org/uniprot/M4V913 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1184267:A11Q_RS10400 ^@ http://purl.uniprot.org/uniprot/M4VCR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1184267:A11Q_RS08510 ^@ http://purl.uniprot.org/uniprot/M4VCZ8 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1184267:A11Q_RS09625 ^@ http://purl.uniprot.org/uniprot/M4VCC2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1184267:A11Q_RS11170 ^@ http://purl.uniprot.org/uniprot/M4VEH5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1184267:A11Q_RS00085 ^@ http://purl.uniprot.org/uniprot/M4V4H9 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1184267:A11Q_RS02805 ^@ http://purl.uniprot.org/uniprot/M4V6F3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1184267:A11Q_RS05530 ^@ http://purl.uniprot.org/uniprot/M4VQ88 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/1184267:A11Q_RS01290 ^@ http://purl.uniprot.org/uniprot/M4VN40 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1184267:A11Q_RS04075 ^@ http://purl.uniprot.org/uniprot/M4V6P1 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1184267:A11Q_RS09835 ^@ http://purl.uniprot.org/uniprot/M4V9U3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1184267:A11Q_RS05170 ^@ http://purl.uniprot.org/uniprot/M4V774 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS06395 ^@ http://purl.uniprot.org/uniprot/M4V8H4 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1184267:A11Q_RS02260 ^@ http://purl.uniprot.org/uniprot/M4V655 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/1184267:A11Q_RS13570 ^@ http://purl.uniprot.org/uniprot/M4V9M7 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1184267:A11Q_RS02850 ^@ http://purl.uniprot.org/uniprot/M4V601 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS06545 ^@ http://purl.uniprot.org/uniprot/M4V813 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS01245 ^@ http://purl.uniprot.org/uniprot/M4VN31 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/1184267:A11Q_RS11500 ^@ http://purl.uniprot.org/uniprot/M4VEQ3 ^@ Similarity ^@ Belongs to the nitroreductase family. http://togogenome.org/gene/1184267:A11Q_RS10135 ^@ http://purl.uniprot.org/uniprot/M4V9Z8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS08420 ^@ http://purl.uniprot.org/uniprot/M4VRS9 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1184267:A11Q_RS09535 ^@ http://purl.uniprot.org/uniprot/M4V9P0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1184267:A11Q_RS07410 ^@ http://purl.uniprot.org/uniprot/M4V8G8 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1184267:A11Q_RS11680 ^@ http://purl.uniprot.org/uniprot/M4VAY3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12900 ^@ http://purl.uniprot.org/uniprot/M4VC12 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1184267:A11Q_RS07040 ^@ http://purl.uniprot.org/uniprot/M4VR22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00290 ^@ http://purl.uniprot.org/uniprot/M4VMG9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1184267:A11Q_RS01280 ^@ http://purl.uniprot.org/uniprot/M4V901 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS06535 ^@ http://purl.uniprot.org/uniprot/M4VAN4 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS06405 ^@ http://purl.uniprot.org/uniprot/M4VAL5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1184267:A11Q_RS09665 ^@ http://purl.uniprot.org/uniprot/M4VA94 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1184267:A11Q_RS00440 ^@ http://purl.uniprot.org/uniprot/M4VMJ7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09155 ^@ http://purl.uniprot.org/uniprot/M4VDD7 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1184267:A11Q_RS06300 ^@ http://purl.uniprot.org/uniprot/M4VAJ5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1184267:A11Q_RS02495 ^@ http://purl.uniprot.org/uniprot/M4V9L7 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1184267:A11Q_RS13925 ^@ http://purl.uniprot.org/uniprot/M4V9C7 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1184267:A11Q_RS08465 ^@ http://purl.uniprot.org/uniprot/M4V916 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09445 ^@ http://purl.uniprot.org/uniprot/M4VSC3 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/1184267:A11Q_RS12990 ^@ http://purl.uniprot.org/uniprot/M4VBM3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS00090 ^@ http://purl.uniprot.org/uniprot/M4V4Y2 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1184267:A11Q_RS08230 ^@ http://purl.uniprot.org/uniprot/M4VCT9 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1184267:A11Q_RS04900 ^@ http://purl.uniprot.org/uniprot/M4V722 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12880 ^@ http://purl.uniprot.org/uniprot/M4VU83 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1184267:A11Q_RS04340 ^@ http://purl.uniprot.org/uniprot/M4VAP2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1184267:A11Q_RS03990 ^@ http://purl.uniprot.org/uniprot/M4V9A1 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03700 ^@ http://purl.uniprot.org/uniprot/M4V6Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS05080 ^@ http://purl.uniprot.org/uniprot/M4V7N4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10290 ^@ http://purl.uniprot.org/uniprot/M4VAK0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1184267:A11Q_RS00960 ^@ http://purl.uniprot.org/uniprot/M4V5F2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09735 ^@ http://purl.uniprot.org/uniprot/M4V9S5 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10885 ^@ http://purl.uniprot.org/uniprot/M4VAE2 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS01975 ^@ http://purl.uniprot.org/uniprot/M4V5J6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1184267:A11Q_RS06475 ^@ http://purl.uniprot.org/uniprot/M4VQT4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1184267:A11Q_RS03695 ^@ http://purl.uniprot.org/uniprot/M4V6F6 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1184267:A11Q_RS03905 ^@ http://purl.uniprot.org/uniprot/M4V733 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS13090 ^@ http://purl.uniprot.org/uniprot/M4VBP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1184267:A11Q_RS07555 ^@ http://purl.uniprot.org/uniprot/M4V8J5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS10820 ^@ http://purl.uniprot.org/uniprot/M4VT29 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1184267:A11Q_RS09920 ^@ http://purl.uniprot.org/uniprot/M4VSJ5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1184267:A11Q_RS06940 ^@ http://purl.uniprot.org/uniprot/M4V884 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09170 ^@ http://purl.uniprot.org/uniprot/M4VS76 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1184267:A11Q_RS09065 ^@ http://purl.uniprot.org/uniprot/M4V9Z7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1184267:A11Q_RS02605 ^@ http://purl.uniprot.org/uniprot/M4V5V4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1184267:A11Q_RS07230 ^@ http://purl.uniprot.org/uniprot/M4VC95 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS06310 ^@ http://purl.uniprot.org/uniprot/M4V7X0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1184267:A11Q_RS02240 ^@ http://purl.uniprot.org/uniprot/M4VNJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03290 ^@ http://purl.uniprot.org/uniprot/M4V6P6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09570 ^@ http://purl.uniprot.org/uniprot/M4VSE5 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1184267:A11Q_RS12050 ^@ http://purl.uniprot.org/uniprot/M4VEZ5 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1184267:A11Q_RS00925 ^@ http://purl.uniprot.org/uniprot/M4V8R4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1184267:A11Q_RS05420 ^@ http://purl.uniprot.org/uniprot/M4V7C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS06305 ^@ http://purl.uniprot.org/uniprot/M4VBU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1184267:A11Q_RS00285 ^@ http://purl.uniprot.org/uniprot/M4V518 ^@ Similarity ^@ Belongs to the diaminopimelate epimerase family. http://togogenome.org/gene/1184267:A11Q_RS11065 ^@ http://purl.uniprot.org/uniprot/M4VT77 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS06250 ^@ http://purl.uniprot.org/uniprot/M4VAG3 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/1184267:A11Q_RS09740 ^@ http://purl.uniprot.org/uniprot/M4VAA4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS08115 ^@ http://purl.uniprot.org/uniprot/M4V8U9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1184267:A11Q_RS08240 ^@ http://purl.uniprot.org/uniprot/M4V9F8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1184267:A11Q_RS04915 ^@ http://purl.uniprot.org/uniprot/M4V9R9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1184267:A11Q_RS11230 ^@ http://purl.uniprot.org/uniprot/M4VB58 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/1184267:A11Q_RS11600 ^@ http://purl.uniprot.org/uniprot/M4VER8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1184267:A11Q_RS06820 ^@ http://purl.uniprot.org/uniprot/M4V861 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1184267:A11Q_RS03680 ^@ http://purl.uniprot.org/uniprot/M4VP93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS02810 ^@ http://purl.uniprot.org/uniprot/M4VNT6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1184267:A11Q_RS13065 ^@ http://purl.uniprot.org/uniprot/M4VBN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04160 ^@ http://purl.uniprot.org/uniprot/M4VPJ7 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1184267:A11Q_RS13170 ^@ http://purl.uniprot.org/uniprot/M4VC66 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1184267:A11Q_RS04950 ^@ http://purl.uniprot.org/uniprot/M4V732 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS12005 ^@ http://purl.uniprot.org/uniprot/M4VB41 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1184267:A11Q_RS03175 ^@ http://purl.uniprot.org/uniprot/M4VA01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09125 ^@ http://purl.uniprot.org/uniprot/M4VC37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS00665 ^@ http://purl.uniprot.org/uniprot/M4V7E3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS00825 ^@ http://purl.uniprot.org/uniprot/M4V4X2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04755 ^@ http://purl.uniprot.org/uniprot/M4V7I0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04620 ^@ http://purl.uniprot.org/uniprot/M4VAT6 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1184267:A11Q_RS01615 ^@ http://purl.uniprot.org/uniprot/M4VN89 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MGMT family.|||Cytoplasm|||Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.|||This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles. http://togogenome.org/gene/1184267:A11Q_RS02640 ^@ http://purl.uniprot.org/uniprot/M4VNQ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1184267:A11Q_RS08565 ^@ http://purl.uniprot.org/uniprot/M4V939 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1184267:A11Q_RS12955 ^@ http://purl.uniprot.org/uniprot/M4VE68 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1184267:A11Q_RS12325 ^@ http://purl.uniprot.org/uniprot/M4VB92 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS09235 ^@ http://purl.uniprot.org/uniprot/M4V9I9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TOP6B family.|||Homodimer. Heterotetramer of two Top6A and two Top6B chains.|||Relaxes both positive and negative superturns and exhibits a strong decatenase activity. http://togogenome.org/gene/1184267:A11Q_RS08225 ^@ http://purl.uniprot.org/uniprot/M4VBJ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1184267:A11Q_RS13200 ^@ http://purl.uniprot.org/uniprot/M4V8C3 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1184267:A11Q_RS09595 ^@ http://purl.uniprot.org/uniprot/M4VSF0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1184267:A11Q_RS10120 ^@ http://purl.uniprot.org/uniprot/M4VSN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1184267:A11Q_RS06090 ^@ http://purl.uniprot.org/uniprot/M4V7Q2 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1184267:A11Q_RS08750 ^@ http://purl.uniprot.org/uniprot/M4V978 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1184267:A11Q_RS00215 ^@ http://purl.uniprot.org/uniprot/M4V505 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS05620 ^@ http://purl.uniprot.org/uniprot/M4VBD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12865 ^@ http://purl.uniprot.org/uniprot/M4VFE1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1184267:A11Q_RS13385 ^@ http://purl.uniprot.org/uniprot/M4V6W1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10105 ^@ http://purl.uniprot.org/uniprot/M4VDV4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS03565 ^@ http://purl.uniprot.org/uniprot/M4VA81 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1184267:A11Q_RS04730 ^@ http://purl.uniprot.org/uniprot/M4V7H6 ^@ Similarity ^@ Belongs to the peptidase M17 family. http://togogenome.org/gene/1184267:A11Q_RS03275 ^@ http://purl.uniprot.org/uniprot/M4V8V0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1184267:A11Q_RS12650 ^@ http://purl.uniprot.org/uniprot/M4VBW3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1184267:A11Q_RS09025 ^@ http://purl.uniprot.org/uniprot/M4VDB8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12750 ^@ http://purl.uniprot.org/uniprot/M4VBX9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1184267:A11Q_RS10610 ^@ http://purl.uniprot.org/uniprot/M4VE50 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmJ family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the guanosine in position 1516 of 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS03530 ^@ http://purl.uniprot.org/uniprot/M4VP66 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1184267:A11Q_RS01120 ^@ http://purl.uniprot.org/uniprot/M4V7M9 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1184267:A11Q_RS06375 ^@ http://purl.uniprot.org/uniprot/M4VQR3 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1184267:A11Q_RS10170 ^@ http://purl.uniprot.org/uniprot/M4VSP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS02620 ^@ http://purl.uniprot.org/uniprot/M4V8F6 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1184267:A11Q_RS11385 ^@ http://purl.uniprot.org/uniprot/M4VBB0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1184267:A11Q_RS03490 ^@ http://purl.uniprot.org/uniprot/M4VA66 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1184267:A11Q_RS01355 ^@ http://purl.uniprot.org/uniprot/M4V595 ^@ Similarity ^@ Belongs to the FrmR/RcnR family. http://togogenome.org/gene/1184267:A11Q_RS09220 ^@ http://purl.uniprot.org/uniprot/M4VS86 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1184267:A11Q_RS10985 ^@ http://purl.uniprot.org/uniprot/M4VB03 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1184267:A11Q_RS13115 ^@ http://purl.uniprot.org/uniprot/M4VBP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1184267:A11Q_RS04490 ^@ http://purl.uniprot.org/uniprot/M4V9J2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of glycine to tRNA(Gly).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS06710 ^@ http://purl.uniprot.org/uniprot/M4VAQ9 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1184267:A11Q_RS07340 ^@ http://purl.uniprot.org/uniprot/M4V8Y3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07120 ^@ http://purl.uniprot.org/uniprot/M4VAY5 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1184267:A11Q_RS10260 ^@ http://purl.uniprot.org/uniprot/M4VA21 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1184267:A11Q_RS01485 ^@ http://purl.uniprot.org/uniprot/M4V5S5 ^@ Function|||Similarity ^@ Belongs to the beta-class carbonic anhydrase family.|||Reversible hydration of carbon dioxide. http://togogenome.org/gene/1184267:A11Q_RS08790 ^@ http://purl.uniprot.org/uniprot/M4VBW4 ^@ Similarity ^@ Belongs to the UPRTase family. http://togogenome.org/gene/1184267:A11Q_RS01900 ^@ http://purl.uniprot.org/uniprot/M4V5Z7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10760 ^@ http://purl.uniprot.org/uniprot/M4VAB8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1184267:A11Q_RS10320 ^@ http://purl.uniprot.org/uniprot/M4VSS9 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1184267:A11Q_RS07355 ^@ http://purl.uniprot.org/uniprot/M4VCC0 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1184267:A11Q_RS10490 ^@ http://purl.uniprot.org/uniprot/M4VAP1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS07780 ^@ http://purl.uniprot.org/uniprot/M4V8N9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS11745 ^@ http://purl.uniprot.org/uniprot/M4VDJ7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS05200 ^@ http://purl.uniprot.org/uniprot/M4V7Q7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1184267:A11Q_RS05495 ^@ http://purl.uniprot.org/uniprot/M4V7D9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1184267:A11Q_RS06905 ^@ http://purl.uniprot.org/uniprot/M4VAU3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1184267:A11Q_RS07900 ^@ http://purl.uniprot.org/uniprot/M4VBC7 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1184267:A11Q_RS07710 ^@ http://purl.uniprot.org/uniprot/M4V954 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1184267:A11Q_RS06270 ^@ http://purl.uniprot.org/uniprot/M4VQN8 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1184267:A11Q_RS12745 ^@ http://purl.uniprot.org/uniprot/M4VBH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS09070 ^@ http://purl.uniprot.org/uniprot/M4VS60 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1184267:A11Q_RS09540 ^@ http://purl.uniprot.org/uniprot/M4VA73 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1184267:A11Q_RS13125 ^@ http://purl.uniprot.org/uniprot/M4VUD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1184267:A11Q_RS03720 ^@ http://purl.uniprot.org/uniprot/M4V6H2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09510 ^@ http://purl.uniprot.org/uniprot/M4V9N6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS00845 ^@ http://purl.uniprot.org/uniprot/M4V8Q0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00345 ^@ http://purl.uniprot.org/uniprot/M4V776 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1184267:A11Q_RS04020 ^@ http://purl.uniprot.org/uniprot/M4VAI6 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.|||In the C-terminal section; belongs to the DHPS family. http://togogenome.org/gene/1184267:A11Q_RS00160 ^@ http://purl.uniprot.org/uniprot/M4V4J4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1184267:A11Q_RS05840 ^@ http://purl.uniprot.org/uniprot/M4VQE6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS11940 ^@ http://purl.uniprot.org/uniprot/M4VTR1 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1184267:A11Q_RS05415 ^@ http://purl.uniprot.org/uniprot/M4VB93 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1184267:A11Q_RS00655 ^@ http://purl.uniprot.org/uniprot/M4V590 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1184267:A11Q_RS05255 ^@ http://purl.uniprot.org/uniprot/M4V7R7 ^@ Similarity ^@ Belongs to the helicase family. RecQ subfamily. http://togogenome.org/gene/1184267:A11Q_RS09515 ^@ http://purl.uniprot.org/uniprot/M4VA70 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1184267:A11Q_RS10520 ^@ http://purl.uniprot.org/uniprot/M4VAP6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS03095 ^@ http://purl.uniprot.org/uniprot/M4V9Y4 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1184267:A11Q_RS06685 ^@ http://purl.uniprot.org/uniprot/M4VAQ6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS00710 ^@ http://purl.uniprot.org/uniprot/M4V7F3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1184267:A11Q_RS09150 ^@ http://purl.uniprot.org/uniprot/M4VC41 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS01260 ^@ http://purl.uniprot.org/uniprot/M4V580 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1184267:A11Q_RS07455 ^@ http://purl.uniprot.org/uniprot/M4VCE0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1184267:A11Q_RS08655 ^@ http://purl.uniprot.org/uniprot/M4V9P9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09815 ^@ http://purl.uniprot.org/uniprot/M4VAB7 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1184267:A11Q_RS02795 ^@ http://purl.uniprot.org/uniprot/M4V9S6 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1184267:A11Q_RS10485 ^@ http://purl.uniprot.org/uniprot/M4VA64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1184267:A11Q_RS11250 ^@ http://purl.uniprot.org/uniprot/M4VEJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10150 ^@ http://purl.uniprot.org/uniprot/M4VCL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS07490 ^@ http://purl.uniprot.org/uniprot/M4V912 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS01015 ^@ http://purl.uniprot.org/uniprot/M4VMV6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS11540 ^@ http://purl.uniprot.org/uniprot/M4VTJ7 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1184267:A11Q_RS08560 ^@ http://purl.uniprot.org/uniprot/M4VD09 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07730 ^@ http://purl.uniprot.org/uniprot/M4V8M9 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1184267:A11Q_RS13320 ^@ http://purl.uniprot.org/uniprot/M4V9K6 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1184267:A11Q_RS04035 ^@ http://purl.uniprot.org/uniprot/M4VPG8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09825 ^@ http://purl.uniprot.org/uniprot/M4VCF7 ^@ Function|||Similarity ^@ In the C-terminal section; belongs to the complex I 49 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS07485 ^@ http://purl.uniprot.org/uniprot/M4V8I4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1184267:A11Q_RS13080 ^@ http://purl.uniprot.org/uniprot/M4VE96 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS05270 ^@ http://purl.uniprot.org/uniprot/M4VB67 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1184267:A11Q_RS06265 ^@ http://purl.uniprot.org/uniprot/M4V8D2 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1184267:A11Q_RS06570 ^@ http://purl.uniprot.org/uniprot/M4V816 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS02490 ^@ http://purl.uniprot.org/uniprot/M4V8D8 ^@ Similarity ^@ Belongs to the arginase family. Agmatinase subfamily. http://togogenome.org/gene/1184267:A11Q_RS05790 ^@ http://purl.uniprot.org/uniprot/M4VQD7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS03500 ^@ http://purl.uniprot.org/uniprot/M4V6U1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11945 ^@ http://purl.uniprot.org/uniprot/M4VDN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS10960 ^@ http://purl.uniprot.org/uniprot/M4VAZ8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1184267:A11Q_RS05165 ^@ http://purl.uniprot.org/uniprot/M4VB48 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS01295 ^@ http://purl.uniprot.org/uniprot/M4V7T6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS06500 ^@ http://purl.uniprot.org/uniprot/M4VQT8 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1184267:A11Q_RS11440 ^@ http://purl.uniprot.org/uniprot/M4VTI0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1184267:A11Q_RS13450 ^@ http://purl.uniprot.org/uniprot/M4VA26 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1184267:A11Q_RS03795 ^@ http://purl.uniprot.org/uniprot/M4V6J9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/1184267:A11Q_RS10815 ^@ http://purl.uniprot.org/uniprot/M4VAW2 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1184267:A11Q_RS01130 ^@ http://purl.uniprot.org/uniprot/M4V535 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1184267:A11Q_RS09610 ^@ http://purl.uniprot.org/uniprot/M4V9Q6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL3 family. http://togogenome.org/gene/1184267:A11Q_RS05550 ^@ http://purl.uniprot.org/uniprot/M4VQ92 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/1184267:A11Q_RS03155 ^@ http://purl.uniprot.org/uniprot/M4V654 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09615 ^@ http://purl.uniprot.org/uniprot/M4VA86 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS06635 ^@ http://purl.uniprot.org/uniprot/M4VAP7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1184267:A11Q_RS03000 ^@ http://purl.uniprot.org/uniprot/M4V629 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1184267:A11Q_RS10165 ^@ http://purl.uniprot.org/uniprot/M4VAH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS01360 ^@ http://purl.uniprot.org/uniprot/M4V5Q3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07460 ^@ http://purl.uniprot.org/uniprot/M4V8H8 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/1184267:A11Q_RS08930 ^@ http://purl.uniprot.org/uniprot/M4V9D8 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS09295 ^@ http://purl.uniprot.org/uniprot/M4VS97 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS08130 ^@ http://purl.uniprot.org/uniprot/M4VBH4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1184267:A11Q_RS13150 ^@ http://purl.uniprot.org/uniprot/M4VUE0 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/1184267:A11Q_RS02860 ^@ http://purl.uniprot.org/uniprot/M4VNU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1184267:A11Q_RS09385 ^@ http://purl.uniprot.org/uniprot/M4V9L5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS03280 ^@ http://purl.uniprot.org/uniprot/M4VA24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1184267:A11Q_RS04025 ^@ http://purl.uniprot.org/uniprot/M4V6N1 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/1184267:A11Q_RS10565 ^@ http://purl.uniprot.org/uniprot/M4VA78 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS07605 ^@ http://purl.uniprot.org/uniprot/M4V8K4 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1184267:A11Q_RS04190 ^@ http://purl.uniprot.org/uniprot/M4V9D2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the serine/threonine dehydratase family.|||Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.|||In the native structure, TdcB is in a dimeric form, whereas in the TdcB-AMP complex, it exists in a tetrameric form (dimer of dimers).|||TdcB also dehydrates serine to yield pyruvate via analogous enamine/imine intermediates. http://togogenome.org/gene/1184267:A11Q_RS04295 ^@ http://purl.uniprot.org/uniprot/M4V6S9 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS05435 ^@ http://purl.uniprot.org/uniprot/M4VA09 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1184267:A11Q_RS04855 ^@ http://purl.uniprot.org/uniprot/M4V7J7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1184267:A11Q_RS08845 ^@ http://purl.uniprot.org/uniprot/M4VD82 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/1184267:A11Q_RS03315 ^@ http://purl.uniprot.org/uniprot/M4VA29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1184267:A11Q_RS04085 ^@ http://purl.uniprot.org/uniprot/M4VPI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1184267:A11Q_RS03045 ^@ http://purl.uniprot.org/uniprot/M4V9X4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1184267:A11Q_RS04185 ^@ http://purl.uniprot.org/uniprot/M4VPK2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1184267:A11Q_RS04790 ^@ http://purl.uniprot.org/uniprot/M4V9P6 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11365 ^@ http://purl.uniprot.org/uniprot/M4VTG7 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/1184267:A11Q_RS10965 ^@ http://purl.uniprot.org/uniprot/M4VT58 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09175 ^@ http://purl.uniprot.org/uniprot/M4VC45 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1184267:A11Q_RS09545 ^@ http://purl.uniprot.org/uniprot/M4VSE0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1184267:A11Q_RS07480 ^@ http://purl.uniprot.org/uniprot/M4VCE5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1184267:A11Q_RS10085 ^@ http://purl.uniprot.org/uniprot/M4V9Y6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1184267:A11Q_RS10100 ^@ http://purl.uniprot.org/uniprot/M4VCL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02680 ^@ http://purl.uniprot.org/uniprot/M4V5W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS11760 ^@ http://purl.uniprot.org/uniprot/M4VBH1 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1184267:A11Q_RS11260 ^@ http://purl.uniprot.org/uniprot/M4VB63 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1184267:A11Q_RS06180 ^@ http://purl.uniprot.org/uniprot/M4VBP5 ^@ Function ^@ Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. http://togogenome.org/gene/1184267:A11Q_RS05360 ^@ http://purl.uniprot.org/uniprot/M4V9Z6 ^@ Similarity ^@ Belongs to the SELO family. http://togogenome.org/gene/1184267:A11Q_RS05145 ^@ http://purl.uniprot.org/uniprot/M4V768 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1184267:A11Q_RS03995 ^@ http://purl.uniprot.org/uniprot/M4VAI3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS07525 ^@ http://purl.uniprot.org/uniprot/M4VCF5 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1184267:A11Q_RS00350 ^@ http://purl.uniprot.org/uniprot/M4V8F7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1184267:A11Q_RS11225 ^@ http://purl.uniprot.org/uniprot/M4VAL7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS03895 ^@ http://purl.uniprot.org/uniprot/M4VAG7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1184267:A11Q_RS03060 ^@ http://purl.uniprot.org/uniprot/M4VNX7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell membrane|||Membrane|||Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1184267:A11Q_RS01465 ^@ http://purl.uniprot.org/uniprot/M4VN66 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS09485 ^@ http://purl.uniprot.org/uniprot/M4V9N1 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1184267:A11Q_RS00570 ^@ http://purl.uniprot.org/uniprot/M4V8J7 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1184267:A11Q_RS08490 ^@ http://purl.uniprot.org/uniprot/M4V921 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1184267:A11Q_RS12355 ^@ http://purl.uniprot.org/uniprot/M4VBR5 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1184267:A11Q_RS04665 ^@ http://purl.uniprot.org/uniprot/M4V9M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11595 ^@ http://purl.uniprot.org/uniprot/M4VDH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1184267:A11Q_RS02870 ^@ http://purl.uniprot.org/uniprot/M4V9U0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09060 ^@ http://purl.uniprot.org/uniprot/M4V9F9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1184267:A11Q_RS09440 ^@ http://purl.uniprot.org/uniprot/M4VA59 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/1184267:A11Q_RS09180 ^@ http://purl.uniprot.org/uniprot/M4VDE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07630 ^@ http://purl.uniprot.org/uniprot/M4V8K9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/1184267:A11Q_RS04155 ^@ http://purl.uniprot.org/uniprot/M4V773 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS11070 ^@ http://purl.uniprot.org/uniprot/M4VD50 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS10410 ^@ http://purl.uniprot.org/uniprot/M4VA52 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1184267:A11Q_RS09630 ^@ http://purl.uniprot.org/uniprot/M4VDL9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1184267:A11Q_RS08020 ^@ http://purl.uniprot.org/uniprot/M4VRK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the low molecular weight phosphotyrosine protein phosphatase family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS02075 ^@ http://purl.uniprot.org/uniprot/M4V5K8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1184267:A11Q_RS09950 ^@ http://purl.uniprot.org/uniprot/M4VCI1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS06295 ^@ http://purl.uniprot.org/uniprot/M4VQP9 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1184267:A11Q_RS03725 ^@ http://purl.uniprot.org/uniprot/M4V6Z9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02485 ^@ http://purl.uniprot.org/uniprot/M4VNN4 ^@ Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family. http://togogenome.org/gene/1184267:A11Q_RS08255 ^@ http://purl.uniprot.org/uniprot/M4VCU6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.|||Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS07865 ^@ http://purl.uniprot.org/uniprot/M4V980 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS07765 ^@ http://purl.uniprot.org/uniprot/M4VRF7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1184267:A11Q_RS04250 ^@ http://purl.uniprot.org/uniprot/M4V791 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS04930 ^@ http://purl.uniprot.org/uniprot/M4V7K9 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1184267:A11Q_RS09555 ^@ http://purl.uniprot.org/uniprot/M4VDK7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1184267:A11Q_RS06645 ^@ http://purl.uniprot.org/uniprot/M4V830 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1184267:A11Q_RS02455 ^@ http://purl.uniprot.org/uniprot/M4V690 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1184267:A11Q_RS03750 ^@ http://purl.uniprot.org/uniprot/M4V709 ^@ Similarity ^@ Belongs to the CarB family. http://togogenome.org/gene/1184267:A11Q_RS01155 ^@ http://purl.uniprot.org/uniprot/M4V541 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02535 ^@ http://purl.uniprot.org/uniprot/M4VNP2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00025 ^@ http://purl.uniprot.org/uniprot/M4V716 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1184267:A11Q_RS06210 ^@ http://purl.uniprot.org/uniprot/M4V7S5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS01535 ^@ http://purl.uniprot.org/uniprot/M4V5T4 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1184267:A11Q_RS04600 ^@ http://purl.uniprot.org/uniprot/M4V6X9 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1184267:A11Q_RS00565 ^@ http://purl.uniprot.org/uniprot/M4V7C2 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1184267:A11Q_RS03485 ^@ http://purl.uniprot.org/uniprot/M4V8Y9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1184267:A11Q_RS12375 ^@ http://purl.uniprot.org/uniprot/M4VBA1 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1184267:A11Q_RS02290 ^@ http://purl.uniprot.org/uniprot/M4VNJ9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1184267:A11Q_RS12020 ^@ http://purl.uniprot.org/uniprot/M4VDP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS08090 ^@ http://purl.uniprot.org/uniprot/M4V8U3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1184267:A11Q_RS02065 ^@ http://purl.uniprot.org/uniprot/M4V862 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1184267:A11Q_RS11020 ^@ http://purl.uniprot.org/uniprot/M4VD42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS03900 ^@ http://purl.uniprot.org/uniprot/M4V6L2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1184267:A11Q_RS10345 ^@ http://purl.uniprot.org/uniprot/M4VST4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates ribosomal protein L11. http://togogenome.org/gene/1184267:A11Q_RS04830 ^@ http://purl.uniprot.org/uniprot/M4V7J2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07475 ^@ http://purl.uniprot.org/uniprot/M4VB52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1184267:A11Q_RS10590 ^@ http://purl.uniprot.org/uniprot/M4VA83 ^@ Similarity ^@ Belongs to the LEA type 2 family. http://togogenome.org/gene/1184267:A11Q_RS11125 ^@ http://purl.uniprot.org/uniprot/M4VEG6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1184267:A11Q_RS11380 ^@ http://purl.uniprot.org/uniprot/M4VAT0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1184267:A11Q_RS07575 ^@ http://purl.uniprot.org/uniprot/M4VCG5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00890 ^@ http://purl.uniprot.org/uniprot/M4VMT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1184267:A11Q_RS08520 ^@ http://purl.uniprot.org/uniprot/M4V9M1 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1184267:A11Q_RS01375 ^@ http://purl.uniprot.org/uniprot/M4V920 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02250 ^@ http://purl.uniprot.org/uniprot/M4V9G7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS10765 ^@ http://purl.uniprot.org/uniprot/M4VAV1 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1184267:A11Q_RS06800 ^@ http://purl.uniprot.org/uniprot/M4V8N7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS05010 ^@ http://purl.uniprot.org/uniprot/M4VPZ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1184267:A11Q_RS00265 ^@ http://purl.uniprot.org/uniprot/M4VMG3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03180 ^@ http://purl.uniprot.org/uniprot/M4V660 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09270 ^@ http://purl.uniprot.org/uniprot/M4VS92 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1184267:A11Q_RS09050 ^@ http://purl.uniprot.org/uniprot/M4VC25 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1184267:A11Q_RS13390 ^@ http://purl.uniprot.org/uniprot/M4VPB1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS06460 ^@ http://purl.uniprot.org/uniprot/M4VBW6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS00355 ^@ http://purl.uniprot.org/uniprot/M4V4N0 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1184267:A11Q_RS00005 ^@ http://purl.uniprot.org/uniprot/M4V897 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1184267:A11Q_RS10660 ^@ http://purl.uniprot.org/uniprot/M4VA97 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS07280 ^@ http://purl.uniprot.org/uniprot/M4VB14 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1184267:A11Q_RS09970 ^@ http://purl.uniprot.org/uniprot/M4VSK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS07275 ^@ http://purl.uniprot.org/uniprot/M4VR64 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1184267:A11Q_RS06640 ^@ http://purl.uniprot.org/uniprot/M4VBZ3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1184267:A11Q_RS03330 ^@ http://purl.uniprot.org/uniprot/M4VP27 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1184267:A11Q_RS12655 ^@ http://purl.uniprot.org/uniprot/M4VU35 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1184267:A11Q_RS10455 ^@ http://purl.uniprot.org/uniprot/M4VE23 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1184267:A11Q_RS03055 ^@ http://purl.uniprot.org/uniprot/M4V6J8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1184267:A11Q_RS04815 ^@ http://purl.uniprot.org/uniprot/M4V9Q1 ^@ Function|||Similarity ^@ Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.|||Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. http://togogenome.org/gene/1184267:A11Q_RS06530 ^@ http://purl.uniprot.org/uniprot/M4VQU1 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1184267:A11Q_RS06400 ^@ http://purl.uniprot.org/uniprot/M4VQS0 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit A family. http://togogenome.org/gene/1184267:A11Q_RS02825 ^@ http://purl.uniprot.org/uniprot/M4V5Z6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1184267:A11Q_RS00885 ^@ http://purl.uniprot.org/uniprot/M4V5D5 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1184267:A11Q_RS11290 ^@ http://purl.uniprot.org/uniprot/M4VTC7 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1184267:A11Q_RS09955 ^@ http://purl.uniprot.org/uniprot/M4VDS5 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1184267:A11Q_RS11520 ^@ http://purl.uniprot.org/uniprot/M4VDG0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS06150 ^@ http://purl.uniprot.org/uniprot/M4VQK3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Binds 1 copper ion per subunit, denoted as copper B.|||Binds 2 heme groups per subunit, denoted as high- and low-spin.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00045 ^@ http://purl.uniprot.org/uniprot/M4VMC3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase A chain family.|||Cell membrane|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03385 ^@ http://purl.uniprot.org/uniprot/M4V8W9 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1184267:A11Q_RS02430 ^@ http://purl.uniprot.org/uniprot/M4V685 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1184267:A11Q_RS10140 ^@ http://purl.uniprot.org/uniprot/M4VAH2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS06845 ^@ http://purl.uniprot.org/uniprot/M4V864 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell membrane|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS06280 ^@ http://purl.uniprot.org/uniprot/M4VBS8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1184267:A11Q_RS07725 ^@ http://purl.uniprot.org/uniprot/M4VCJ3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS09760 ^@ http://purl.uniprot.org/uniprot/M4V9S9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS01305 ^@ http://purl.uniprot.org/uniprot/M4V587 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1184267:A11Q_RS05135 ^@ http://purl.uniprot.org/uniprot/M4V9V5 ^@ Similarity ^@ Belongs to the peptidase C1 family. http://togogenome.org/gene/1184267:A11Q_RS04360 ^@ http://purl.uniprot.org/uniprot/M4V9G6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1184267:A11Q_RS03590 ^@ http://purl.uniprot.org/uniprot/M4VA87 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1184267:A11Q_RS09680 ^@ http://purl.uniprot.org/uniprot/M4VCD1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1184267:A11Q_RS00690 ^@ http://purl.uniprot.org/uniprot/M4V7E8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1184267:A11Q_RS05675 ^@ http://purl.uniprot.org/uniprot/M4V7H5 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1184267:A11Q_RS04860 ^@ http://purl.uniprot.org/uniprot/M4VPW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1184267:A11Q_RS10775 ^@ http://purl.uniprot.org/uniprot/M4VCZ0 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1184267:A11Q_RS07635 ^@ http://purl.uniprot.org/uniprot/M4V941 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.|||Belongs to the GSP E family.|||Cell inner membrane http://togogenome.org/gene/1184267:A11Q_RS04170 ^@ http://purl.uniprot.org/uniprot/M4VAK9 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1184267:A11Q_RS03555 ^@ http://purl.uniprot.org/uniprot/M4VP70 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1184267:A11Q_RS06920 ^@ http://purl.uniprot.org/uniprot/M4V8Q7 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1184267:A11Q_RS02725 ^@ http://purl.uniprot.org/uniprot/M4V9R2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1184267:A11Q_RS02765 ^@ http://purl.uniprot.org/uniprot/M4VNT0 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1184267:A11Q_RS08780 ^@ http://purl.uniprot.org/uniprot/M4V9T7 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1184267:A11Q_RS11395 ^@ http://purl.uniprot.org/uniprot/M4VDD8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS09435 ^@ http://purl.uniprot.org/uniprot/M4V9M3 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1184267:A11Q_RS07785 ^@ http://purl.uniprot.org/uniprot/M4V964 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1184267:A11Q_RS08985 ^@ http://purl.uniprot.org/uniprot/M4V9Y5 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1184267:A11Q_RS02340 ^@ http://purl.uniprot.org/uniprot/M4V8B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS05365 ^@ http://purl.uniprot.org/uniprot/M4VB83 ^@ Function|||Similarity|||Subunit ^@ Belongs to the high-potential iron-sulfur protein (HiPIP) family.|||Homodimer.|||Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria. http://togogenome.org/gene/1184267:A11Q_RS00835 ^@ http://purl.uniprot.org/uniprot/M4VMS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS03755 ^@ http://purl.uniprot.org/uniprot/M4VPC2 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1184267:A11Q_RS07305 ^@ http://purl.uniprot.org/uniprot/M4VB19 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/1184267:A11Q_RS09820 ^@ http://purl.uniprot.org/uniprot/M4VSI1 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1184267:A11Q_RS10095 ^@ http://purl.uniprot.org/uniprot/M4VSN0 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1184267:A11Q_RS08145 ^@ http://purl.uniprot.org/uniprot/M4V9D6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1184267:A11Q_RS09560 ^@ http://purl.uniprot.org/uniprot/M4V9P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1184267:A11Q_RS04180 ^@ http://purl.uniprot.org/uniprot/M4V777 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS07420 ^@ http://purl.uniprot.org/uniprot/M4VR89 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/1184267:A11Q_RS10115 ^@ http://purl.uniprot.org/uniprot/M4VAG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1184267:A11Q_RS00405 ^@ http://purl.uniprot.org/uniprot/M4V4P0 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS07075 ^@ http://purl.uniprot.org/uniprot/M4VC68 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1184267:A11Q_RS11865 ^@ http://purl.uniprot.org/uniprot/M4VTP8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS06655 ^@ http://purl.uniprot.org/uniprot/M4VQW1 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS01315 ^@ http://purl.uniprot.org/uniprot/M4VN43 ^@ Similarity ^@ Belongs to the YjdM family. http://togogenome.org/gene/1184267:A11Q_RS09055 ^@ http://purl.uniprot.org/uniprot/M4VDC2 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1184267:A11Q_RS10750 ^@ http://purl.uniprot.org/uniprot/M4VCY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS13120 ^@ http://purl.uniprot.org/uniprot/M4VC58 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1184267:A11Q_RS11655 ^@ http://purl.uniprot.org/uniprot/M4VAX8 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1184267:A11Q_RS10795 ^@ http://purl.uniprot.org/uniprot/M4VT23 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04865 ^@ http://purl.uniprot.org/uniprot/M4V9R0 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1184267:A11Q_RS03850 ^@ http://purl.uniprot.org/uniprot/M4V6K5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS08625 ^@ http://purl.uniprot.org/uniprot/M4V947 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS02685 ^@ http://purl.uniprot.org/uniprot/M4V6D0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS07415 ^@ http://purl.uniprot.org/uniprot/M4V8Z5 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS10875 ^@ http://purl.uniprot.org/uniprot/M4VD12 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidine kinase family.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1184267:A11Q_RS03495 ^@ http://purl.uniprot.org/uniprot/M4V6B7 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS07125 ^@ http://purl.uniprot.org/uniprot/M4VC76 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1184267:A11Q_RS06705 ^@ http://purl.uniprot.org/uniprot/M4VQW7 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1184267:A11Q_RS09135 ^@ http://purl.uniprot.org/uniprot/M4V9H0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1184267:A11Q_RS05100 ^@ http://purl.uniprot.org/uniprot/M4V7N9 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1184267:A11Q_RS08445 ^@ http://purl.uniprot.org/uniprot/M4VRT5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the glyoxalase I family.|||Binds 1 nickel ion per subunit.|||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. http://togogenome.org/gene/1184267:A11Q_RS09655 ^@ http://purl.uniprot.org/uniprot/M4VDM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1184267:A11Q_RS07975 ^@ http://purl.uniprot.org/uniprot/M4VBE3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04870 ^@ http://purl.uniprot.org/uniprot/M4VAY4 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1184267:A11Q_RS04355 ^@ http://purl.uniprot.org/uniprot/M4VPN3 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1184267:A11Q_RS02330 ^@ http://purl.uniprot.org/uniprot/M4V666 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1184267:A11Q_RS09495 ^@ http://purl.uniprot.org/uniprot/M4VSD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1184267:A11Q_RS13440 ^@ http://purl.uniprot.org/uniprot/M4VQ65 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1184267:A11Q_RS02625 ^@ http://purl.uniprot.org/uniprot/M4V9P2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS08375 ^@ http://purl.uniprot.org/uniprot/M4VBM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11150 ^@ http://purl.uniprot.org/uniprot/M4VAJ8 ^@ Function|||Subunit ^@ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).|||Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1184267:A11Q_RS05525 ^@ http://purl.uniprot.org/uniprot/M4V7W4 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1184267:A11Q_RS10935 ^@ http://purl.uniprot.org/uniprot/M4VAF3 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1184267:A11Q_RS00410 ^@ http://purl.uniprot.org/uniprot/M4V542 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1184267:A11Q_RS00940 ^@ http://purl.uniprot.org/uniprot/M4VMU4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Forms a membrane-associated complex with FtsE.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02885 ^@ http://purl.uniprot.org/uniprot/M4VNU8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00820 ^@ http://purl.uniprot.org/uniprot/M4V8P6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00600 ^@ http://purl.uniprot.org/uniprot/M4V4S7 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1184267:A11Q_RS06815 ^@ http://purl.uniprot.org/uniprot/M4VC22 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1184267:A11Q_RS02840 ^@ http://purl.uniprot.org/uniprot/M4V8K7 ^@ Function|||Similarity ^@ Belongs to the FlgN family.|||Required for the efficient initiation of filament assembly. http://togogenome.org/gene/1184267:A11Q_RS01695 ^@ http://purl.uniprot.org/uniprot/M4V7Z8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS09725 ^@ http://purl.uniprot.org/uniprot/M4VCD6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS07450 ^@ http://purl.uniprot.org/uniprot/M4VB47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09580 ^@ http://purl.uniprot.org/uniprot/M4VDL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1184267:A11Q_RS03075 ^@ http://purl.uniprot.org/uniprot/M4V642 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1184267:A11Q_RS09645 ^@ http://purl.uniprot.org/uniprot/M4VSF8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1184267:A11Q_RS12950 ^@ http://purl.uniprot.org/uniprot/M4VU99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1184267:A11Q_RS07685 ^@ http://purl.uniprot.org/uniprot/M4V949 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS13140 ^@ http://purl.uniprot.org/uniprot/M4VBP8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase B chain family.|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04780 ^@ http://purl.uniprot.org/uniprot/M4V7I4 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1184267:A11Q_RS05595 ^@ http://purl.uniprot.org/uniprot/M4V7G0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1184267:A11Q_RS07390 ^@ http://purl.uniprot.org/uniprot/M4V8Z1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS06390 ^@ http://purl.uniprot.org/uniprot/M4V7Y5 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1184267:A11Q_RS09130 ^@ http://purl.uniprot.org/uniprot/M4VDD1 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1184267:A11Q_RS11405 ^@ http://purl.uniprot.org/uniprot/M4VAT5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS08720 ^@ http://purl.uniprot.org/uniprot/M4VD40 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12220 ^@ http://purl.uniprot.org/uniprot/M4VF19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS13195 ^@ http://purl.uniprot.org/uniprot/M4VC72 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1184267:A11Q_RS01150 ^@ http://purl.uniprot.org/uniprot/M4V8V8 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/1184267:A11Q_RS02525 ^@ http://purl.uniprot.org/uniprot/M4V5T9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1184267:A11Q_RS02705 ^@ http://purl.uniprot.org/uniprot/M4V5X4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS05280 ^@ http://purl.uniprot.org/uniprot/M4V7S0 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/1184267:A11Q_RS11205 ^@ http://purl.uniprot.org/uniprot/M4VB51 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS03025 ^@ http://purl.uniprot.org/uniprot/M4V633 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS05235 ^@ http://purl.uniprot.org/uniprot/M4V9X3 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1184267:A11Q_RS00790 ^@ http://purl.uniprot.org/uniprot/M4V8P0 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1184267:A11Q_RS12835 ^@ http://purl.uniprot.org/uniprot/M4VE43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS01180 ^@ http://purl.uniprot.org/uniprot/M4V544 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1184267:A11Q_RS01575 ^@ http://purl.uniprot.org/uniprot/M4V953 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1184267:A11Q_RS11860 ^@ http://purl.uniprot.org/uniprot/M4VBI7 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1184267:A11Q_RS04220 ^@ http://purl.uniprot.org/uniprot/M4VAL8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1184267:A11Q_RS10690 ^@ http://purl.uniprot.org/uniprot/M4VAT1 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1184267:A11Q_RS11555 ^@ http://purl.uniprot.org/uniprot/M4VAW1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS09670 ^@ http://purl.uniprot.org/uniprot/M4VSG2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09635 ^@ http://purl.uniprot.org/uniprot/M4V9R1 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1184267:A11Q_RS07715 ^@ http://purl.uniprot.org/uniprot/M4VRE6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1184267:A11Q_RS07105 ^@ http://purl.uniprot.org/uniprot/M4V8B6 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS01340 ^@ http://purl.uniprot.org/uniprot/M4VN48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00320 ^@ http://purl.uniprot.org/uniprot/M4V770 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04405 ^@ http://purl.uniprot.org/uniprot/M4V7B5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS13165 ^@ http://purl.uniprot.org/uniprot/M4VBQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS04910 ^@ http://purl.uniprot.org/uniprot/M4VPX5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1184267:A11Q_RS10350 ^@ http://purl.uniprot.org/uniprot/M4VCQ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS09140 ^@ http://purl.uniprot.org/uniprot/M4VA10 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1184267:A11Q_RS07795 ^@ http://purl.uniprot.org/uniprot/M4VBA8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1184267:A11Q_RS06995 ^@ http://purl.uniprot.org/uniprot/M4VAW3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS03360 ^@ http://purl.uniprot.org/uniprot/M4V8W4 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1184267:A11Q_RS07770 ^@ http://purl.uniprot.org/uniprot/M4VBA4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1184267:A11Q_RS05995 ^@ http://purl.uniprot.org/uniprot/M4V867 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1184267:A11Q_RS12215 ^@ http://purl.uniprot.org/uniprot/M4VDS4 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1184267:A11Q_RS04400 ^@ http://purl.uniprot.org/uniprot/M4V6U6 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1184267:A11Q_RS10810 ^@ http://purl.uniprot.org/uniprot/M4VAC7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1184267:A11Q_RS13220 ^@ http://purl.uniprot.org/uniprot/M4V7D2 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1184267:A11Q_RS03010 ^@ http://purl.uniprot.org/uniprot/M4VNW8 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1184267:A11Q_RS03770 ^@ http://purl.uniprot.org/uniprot/M4V6J5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1184267:A11Q_RS08205 ^@ http://purl.uniprot.org/uniprot/M4VCT6 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1184267:A11Q_RS05260 ^@ http://purl.uniprot.org/uniprot/M4VQ41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS02355 ^@ http://purl.uniprot.org/uniprot/M4V669 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS09550 ^@ http://purl.uniprot.org/uniprot/M4VCA8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1184267:A11Q_RS05290 ^@ http://purl.uniprot.org/uniprot/M4V9Y2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS06540 ^@ http://purl.uniprot.org/uniprot/M4VBX7 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TtcA family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is chelated by three Cys residues, the fourth Fe has a free coordination site that may bind a sulfur atom transferred from the persulfide of IscS.|||Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system.|||Cytoplasm|||Homodimer.|||The thiolation reaction likely consists of two steps: a first activation step by ATP to form an adenylated intermediate of the target base of tRNA, and a second nucleophilic substitution step of the sulfur (S) atom supplied by the hydrosulfide attached to the Fe-S cluster. http://togogenome.org/gene/1184267:A11Q_RS04300 ^@ http://purl.uniprot.org/uniprot/M4V799 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell membrane http://togogenome.org/gene/1184267:A11Q_RS04895 ^@ http://purl.uniprot.org/uniprot/M4VAZ0 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1184267:A11Q_RS07140 ^@ http://purl.uniprot.org/uniprot/M4VR40 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1184267:A11Q_RS12335 ^@ http://purl.uniprot.org/uniprot/M4VTX6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02580 ^@ http://purl.uniprot.org/uniprot/M4V5V0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S41B family.|||Cytoplasm|||Degrades oligopeptides. http://togogenome.org/gene/1184267:A11Q_RS11710 ^@ http://purl.uniprot.org/uniprot/M4VBG2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1184267:A11Q_RS13075 ^@ http://purl.uniprot.org/uniprot/M4VUC5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS07055 ^@ http://purl.uniprot.org/uniprot/M4V8A7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1184267:A11Q_RS07640 ^@ http://purl.uniprot.org/uniprot/M4VRD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00340 ^@ http://purl.uniprot.org/uniprot/M4VMH6 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1184267:A11Q_RS00295 ^@ http://purl.uniprot.org/uniprot/M4V765 ^@ Similarity ^@ Belongs to the DapB family. http://togogenome.org/gene/1184267:A11Q_RS09660 ^@ http://purl.uniprot.org/uniprot/M4V9R6 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1184267:A11Q_RS05975 ^@ http://purl.uniprot.org/uniprot/M4VQG9 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS04380 ^@ http://purl.uniprot.org/uniprot/M4V9H1 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/1184267:A11Q_RS04775 ^@ http://purl.uniprot.org/uniprot/M4V705 ^@ Similarity|||Subunit ^@ Belongs to the GTP cyclohydrolase I family.|||Homopolymer. http://togogenome.org/gene/1184267:A11Q_RS12910 ^@ http://purl.uniprot.org/uniprot/M4VE58 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04625 ^@ http://purl.uniprot.org/uniprot/M4V6Y3 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1184267:A11Q_RS07130 ^@ http://purl.uniprot.org/uniprot/M4V8C2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1184267:A11Q_RS09720 ^@ http://purl.uniprot.org/uniprot/M4VSG6 ^@ Function ^@ Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). http://togogenome.org/gene/1184267:A11Q_RS03670 ^@ http://purl.uniprot.org/uniprot/M4V6F1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS11640 ^@ http://purl.uniprot.org/uniprot/M4VTL3 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1184267:A11Q_RS11535 ^@ http://purl.uniprot.org/uniprot/M4VBD6 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily.|||Belongs to the spermidine/spermine synthase family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Heterotetramer of two alpha and two beta chains arranged as a dimer of alpha/beta heterodimers.|||Homodimer or homotetramer.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl group blocking the N-terminus of the alpha chain.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS00995 ^@ http://purl.uniprot.org/uniprot/M4V7K8 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1184267:A11Q_RS07295 ^@ http://purl.uniprot.org/uniprot/M4V8X3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/1184267:A11Q_RS07705 ^@ http://purl.uniprot.org/uniprot/M4V8M4 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1184267:A11Q_RS07330 ^@ http://purl.uniprot.org/uniprot/M4VCB5 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1184267:A11Q_RS04285 ^@ http://purl.uniprot.org/uniprot/M4V9F2 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS05350 ^@ http://purl.uniprot.org/uniprot/M4V7A9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1184267:A11Q_RS07660 ^@ http://purl.uniprot.org/uniprot/M4V945 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP J family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02880 ^@ http://purl.uniprot.org/uniprot/M4V6G5 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1184267:A11Q_RS10640 ^@ http://purl.uniprot.org/uniprot/M4VA93 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1184267:A11Q_RS08060 ^@ http://purl.uniprot.org/uniprot/M4V8T8 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1184267:A11Q_RS09100 ^@ http://purl.uniprot.org/uniprot/M4VC35 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1184267:A11Q_RS12930 ^@ http://purl.uniprot.org/uniprot/M4VU95 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1184267:A11Q_RS00050 ^@ http://purl.uniprot.org/uniprot/M4V720 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase C chain family.|||Cell membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10705 ^@ http://purl.uniprot.org/uniprot/M4VE72 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS09605 ^@ http://purl.uniprot.org/uniprot/M4VDL5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS10405 ^@ http://purl.uniprot.org/uniprot/M4VE13 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1184267:A11Q_RS08190 ^@ http://purl.uniprot.org/uniprot/M4V9E8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS00670 ^@ http://purl.uniprot.org/uniprot/M4V8L7 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1184267:A11Q_RS01495 ^@ http://purl.uniprot.org/uniprot/M4V7W7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10180 ^@ http://purl.uniprot.org/uniprot/M4VDX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1184267:A11Q_RS06840 ^@ http://purl.uniprot.org/uniprot/M4VC27 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1184267:A11Q_RS12945 ^@ http://purl.uniprot.org/uniprot/M4VC23 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1184267:A11Q_RS02835 ^@ http://purl.uniprot.org/uniprot/M4VNU0 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/1184267:A11Q_RS13185 ^@ http://purl.uniprot.org/uniprot/M4VFK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1184267:A11Q_RS12720 ^@ http://purl.uniprot.org/uniprot/M4VBG9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS03985 ^@ http://purl.uniprot.org/uniprot/M4VPF9 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1184267:A11Q_RS04480 ^@ http://purl.uniprot.org/uniprot/M4V7D0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS09590 ^@ http://purl.uniprot.org/uniprot/M4VA82 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1184267:A11Q_RS04510 ^@ http://purl.uniprot.org/uniprot/M4VPQ9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1184267:A11Q_RS07920 ^@ http://purl.uniprot.org/uniprot/M4VRI5 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1184267:A11Q_RS02380 ^@ http://purl.uniprot.org/uniprot/M4V675 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1184267:A11Q_RS08480 ^@ http://purl.uniprot.org/uniprot/M4VBP3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS10240 ^@ http://purl.uniprot.org/uniprot/M4VAI9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1184267:A11Q_RS02280 ^@ http://purl.uniprot.org/uniprot/M4V5P1 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1184267:A11Q_RS04850 ^@ http://purl.uniprot.org/uniprot/M4V715 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1184267:A11Q_RS00415 ^@ http://purl.uniprot.org/uniprot/M4VMJ1 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1184267:A11Q_RS12980 ^@ http://purl.uniprot.org/uniprot/M4VE74 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1184267:A11Q_RS00875 ^@ http://purl.uniprot.org/uniprot/M4V8Q4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1184267:A11Q_RS04810 ^@ http://purl.uniprot.org/uniprot/M4VPV9 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1184267:A11Q_RS07980 ^@ http://purl.uniprot.org/uniprot/M4VCN8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04590 ^@ http://purl.uniprot.org/uniprot/M4V9L0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02410 ^@ http://purl.uniprot.org/uniprot/M4VNM2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS03715 ^@ http://purl.uniprot.org/uniprot/M4VAB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1184267:A11Q_RS04205 ^@ http://purl.uniprot.org/uniprot/M4V782 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS05985 ^@ http://purl.uniprot.org/uniprot/M4VBK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS00010 ^@ http://purl.uniprot.org/uniprot/M4V4G4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1184267:A11Q_RS04825 ^@ http://purl.uniprot.org/uniprot/M4V712 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1184267:A11Q_RS03020 ^@ http://purl.uniprot.org/uniprot/M4V9W9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10065 ^@ http://purl.uniprot.org/uniprot/M4VAG0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS09450 ^@ http://purl.uniprot.org/uniprot/M4VC89 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1184267:A11Q_RS08535 ^@ http://purl.uniprot.org/uniprot/M4VD03 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS04275 ^@ http://purl.uniprot.org/uniprot/M4V795 ^@ Caution|||Function|||Similarity ^@ Belongs to the NrdR family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1184267:A11Q_RS07405 ^@ http://purl.uniprot.org/uniprot/M4VCD0 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1184267:A11Q_RS00590 ^@ http://purl.uniprot.org/uniprot/M4V7C7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS01490 ^@ http://purl.uniprot.org/uniprot/M4VN69 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1184267:A11Q_RS13530 ^@ http://purl.uniprot.org/uniprot/M4VAX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10825 ^@ http://purl.uniprot.org/uniprot/M4VD02 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1184267:A11Q_RS12685 ^@ http://purl.uniprot.org/uniprot/M4VE17 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1184267:A11Q_RS08475 ^@ http://purl.uniprot.org/uniprot/M4VRU0 ^@ Caution|||Function|||Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.|||Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS09490 ^@ http://purl.uniprot.org/uniprot/M4VA65 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1184267:A11Q_RS03435 ^@ http://purl.uniprot.org/uniprot/M4V8X8 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1184267:A11Q_RS09575 ^@ http://purl.uniprot.org/uniprot/M4VCB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS05195 ^@ http://purl.uniprot.org/uniprot/M4V779 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1184267:A11Q_RS09260 ^@ http://purl.uniprot.org/uniprot/M4V9J4 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1184267:A11Q_RS06950 ^@ http://purl.uniprot.org/uniprot/M4VAV2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1184267:A11Q_RS12480 ^@ http://purl.uniprot.org/uniprot/M4VBT4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1184267:A11Q_RS04120 ^@ http://purl.uniprot.org/uniprot/M4VAJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS03875 ^@ http://purl.uniprot.org/uniprot/M4V6K9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS04675 ^@ http://purl.uniprot.org/uniprot/M4V6Z1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS03740 ^@ http://purl.uniprot.org/uniprot/M4VAD1 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1184267:A11Q_RS13520 ^@ http://purl.uniprot.org/uniprot/M4VQZ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS04495 ^@ http://purl.uniprot.org/uniprot/M4VAR4 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1184267:A11Q_RS07020 ^@ http://purl.uniprot.org/uniprot/M4VAW8 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1184267:A11Q_RS08210 ^@ http://purl.uniprot.org/uniprot/M4V8X0 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1184267:A11Q_RS05720 ^@ http://purl.uniprot.org/uniprot/M4VA63 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1184267:A11Q_RS05390 ^@ http://purl.uniprot.org/uniprot/M4VB89 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1184267:A11Q_RS09250 ^@ http://purl.uniprot.org/uniprot/M4VC57 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS06930 ^@ http://purl.uniprot.org/uniprot/M4VAU8 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1184267:A11Q_RS03090 ^@ http://purl.uniprot.org/uniprot/M4V8Q1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS08540 ^@ http://purl.uniprot.org/uniprot/M4V933 ^@ Function|||Similarity ^@ Belongs to the RNase Y family.|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1184267:A11Q_RS06850 ^@ http://purl.uniprot.org/uniprot/M4V8P5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS11935 ^@ http://purl.uniprot.org/uniprot/M4VBK1 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1184267:A11Q_RS06770 ^@ http://purl.uniprot.org/uniprot/M4V850 ^@ Similarity ^@ Belongs to the SufE family. http://togogenome.org/gene/1184267:A11Q_RS10500 ^@ http://purl.uniprot.org/uniprot/M4VCT4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1184267:A11Q_RS12465 ^@ http://purl.uniprot.org/uniprot/M4VDX1 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1184267:A11Q_RS09565 ^@ http://purl.uniprot.org/uniprot/M4VA77 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS05735 ^@ http://purl.uniprot.org/uniprot/M4V811 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1184267:A11Q_RS09460 ^@ http://purl.uniprot.org/uniprot/M4V9M8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS10595 ^@ http://purl.uniprot.org/uniprot/M4VAR0 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1184267:A11Q_RS02385 ^@ http://purl.uniprot.org/uniprot/M4VNL7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GDT1 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS04820 ^@ http://purl.uniprot.org/uniprot/M4VAX6 ^@ Similarity ^@ Belongs to the PrpD family. http://togogenome.org/gene/1184267:A11Q_RS12875 ^@ http://purl.uniprot.org/uniprot/M4VC07 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS12735 ^@ http://purl.uniprot.org/uniprot/M4VE26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1184267:A11Q_RS01590 ^@ http://purl.uniprot.org/uniprot/M4VN84 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acyl-ACP thioesterase family.|||chloroplast http://togogenome.org/gene/1184267:A11Q_RS09160 ^@ http://purl.uniprot.org/uniprot/M4V9H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS00105 ^@ http://purl.uniprot.org/uniprot/M4V8B8 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1184267:A11Q_RS06615 ^@ http://purl.uniprot.org/uniprot/M4VBY8 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1184267:A11Q_RS10155 ^@ http://purl.uniprot.org/uniprot/M4VDW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS04330 ^@ http://purl.uniprot.org/uniprot/M4VPN0 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1184267:A11Q_RS11980 ^@ http://purl.uniprot.org/uniprot/M4VB36 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1184267:A11Q_RS08710 ^@ http://purl.uniprot.org/uniprot/M4VRZ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS08325 ^@ http://purl.uniprot.org/uniprot/M4VBL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS13110 ^@ http://purl.uniprot.org/uniprot/M4VFJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1184267:A11Q_RS02300 ^@ http://purl.uniprot.org/uniprot/M4V9H7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1184267:A11Q_RS13355 ^@ http://purl.uniprot.org/uniprot/M4V645 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1184267:A11Q_RS03950 ^@ http://purl.uniprot.org/uniprot/M4V6M0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1184267:A11Q_RS03510 ^@ http://purl.uniprot.org/uniprot/M4V8Z3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS07790 ^@ http://purl.uniprot.org/uniprot/M4VRG0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1184267:A11Q_RS04840 ^@ http://purl.uniprot.org/uniprot/M4V9Q5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1184267:A11Q_RS10620 ^@ http://purl.uniprot.org/uniprot/M4VAR5 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1184267:A11Q_RS04210 ^@ http://purl.uniprot.org/uniprot/M4VPK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS02760 ^@ http://purl.uniprot.org/uniprot/M4V6E5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1184267:A11Q_RS03310 ^@ http://purl.uniprot.org/uniprot/M4V8V5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1184267:A11Q_RS06865 ^@ http://purl.uniprot.org/uniprot/M4VC31 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1184267:A11Q_RS09530 ^@ http://purl.uniprot.org/uniprot/M4VDK3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1184267:A11Q_RS02755 ^@ http://purl.uniprot.org/uniprot/M4V5Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS07530 ^@ http://purl.uniprot.org/uniprot/M4V8J1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/1184267:A11Q_RS05125 ^@ http://purl.uniprot.org/uniprot/M4V7P4 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1184267:A11Q_RS03620 ^@ http://purl.uniprot.org/uniprot/M4V6E1 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS07750 ^@ http://purl.uniprot.org/uniprot/M4VCJ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS00735 ^@ http://purl.uniprot.org/uniprot/M4V7F8 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1184267:A11Q_RS09985 ^@ http://purl.uniprot.org/uniprot/M4V9W8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1184267:A11Q_RS09990 ^@ http://purl.uniprot.org/uniprot/M4VAE4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS10425 ^@ http://purl.uniprot.org/uniprot/M4VCS0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1184267:A11Q_RS09075 ^@ http://purl.uniprot.org/uniprot/M4VC29 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1184267:A11Q_RS07540 ^@ http://purl.uniprot.org/uniprot/M4VRB1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1184267:A11Q_RS09805 ^@ http://purl.uniprot.org/uniprot/M4VDP4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1184267:A11Q_RS13420 ^@ http://purl.uniprot.org/uniprot/M4VAW0 ^@ Subcellular Location Annotation ^@ Cell outer membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS12740 ^@ http://purl.uniprot.org/uniprot/M4VFB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1184267:A11Q_RS10700 ^@ http://purl.uniprot.org/uniprot/M4VCX5 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1184267:A11Q_RS06365 ^@ http://purl.uniprot.org/uniprot/M4V7Y0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02590 ^@ http://purl.uniprot.org/uniprot/M4VNQ0 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1184267:A11Q_RS00240 ^@ http://purl.uniprot.org/uniprot/M4VMF9 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1184267:A11Q_RS12570 ^@ http://purl.uniprot.org/uniprot/M4VBE0 ^@ Similarity ^@ Belongs to the NodU/CmcH family. http://togogenome.org/gene/1184267:A11Q_RS01630 ^@ http://purl.uniprot.org/uniprot/M4V5E0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1184267:A11Q_RS04705 ^@ http://purl.uniprot.org/uniprot/M4V7H1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1184267:A11Q_RS02425 ^@ http://purl.uniprot.org/uniprot/M4V5R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS02955 ^@ http://purl.uniprot.org/uniprot/M4V6H9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1184267:A11Q_RS10160 ^@ http://purl.uniprot.org/uniprot/M4VA00 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS05965 ^@ http://purl.uniprot.org/uniprot/M4V7M6 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily. http://togogenome.org/gene/1184267:A11Q_RS01710 ^@ http://purl.uniprot.org/uniprot/M4V5W3 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1184267:A11Q_RS02555 ^@ http://purl.uniprot.org/uniprot/M4V5U4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07890 ^@ http://purl.uniprot.org/uniprot/M4V985 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1184267:A11Q_RS06835 ^@ http://purl.uniprot.org/uniprot/M4VAS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00540 ^@ http://purl.uniprot.org/uniprot/M4V7B7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS03975 ^@ http://purl.uniprot.org/uniprot/M4V6M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type IA topoisomerase family.|||Monomer.|||Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone. http://togogenome.org/gene/1184267:A11Q_RS12640 ^@ http://purl.uniprot.org/uniprot/M4VF97 ^@ Caution|||Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS03065 ^@ http://purl.uniprot.org/uniprot/M4V8P7 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/1184267:A11Q_RS10680 ^@ http://purl.uniprot.org/uniprot/M4VE66 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1184267:A11Q_RS03285 ^@ http://purl.uniprot.org/uniprot/M4V678 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1184267:A11Q_RS11575 ^@ http://purl.uniprot.org/uniprot/M4VER4 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1184267:A11Q_RS01640 ^@ http://purl.uniprot.org/uniprot/M4VN94 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1184267:A11Q_RS03625 ^@ http://purl.uniprot.org/uniprot/M4V6W8 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1184267:A11Q_RS02230 ^@ http://purl.uniprot.org/uniprot/M4V5N1 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1184267:A11Q_RS02710 ^@ http://purl.uniprot.org/uniprot/M4V6D4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS11880 ^@ http://purl.uniprot.org/uniprot/M4VB18 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1184267:A11Q_RS08330 ^@ http://purl.uniprot.org/uniprot/M4VCW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS06760 ^@ http://purl.uniprot.org/uniprot/M4VAR6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS03375 ^@ http://purl.uniprot.org/uniprot/M4V6R2 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1184267:A11Q_RS07350 ^@ http://purl.uniprot.org/uniprot/M4VB29 ^@ Similarity ^@ Belongs to the bacterial sugar transferase family. http://togogenome.org/gene/1184267:A11Q_RS00300 ^@ http://purl.uniprot.org/uniprot/M4V8E8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1184267:A11Q_RS07070 ^@ http://purl.uniprot.org/uniprot/M4VAX7 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1184267:A11Q_RS00660 ^@ http://purl.uniprot.org/uniprot/M4VMP3 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by GTP. Inhibited by UTP.|||Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS04045 ^@ http://purl.uniprot.org/uniprot/M4VAJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS02585 ^@ http://purl.uniprot.org/uniprot/M4V6B4 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1184267:A11Q_RS10250 ^@ http://purl.uniprot.org/uniprot/M4VCN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS11970 ^@ http://purl.uniprot.org/uniprot/M4VDN3 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS05820 ^@ http://purl.uniprot.org/uniprot/M4VA80 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS06665 ^@ http://purl.uniprot.org/uniprot/M4VBZ8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1184267:A11Q_RS01875 ^@ http://purl.uniprot.org/uniprot/M4V5H9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS10805 ^@ http://purl.uniprot.org/uniprot/M4VE94 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02370 ^@ http://purl.uniprot.org/uniprot/M4V9J1 ^@ Similarity ^@ Belongs to the EPSP synthase family. http://togogenome.org/gene/1184267:A11Q_RS07085 ^@ http://purl.uniprot.org/uniprot/M4V8T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS05635 ^@ http://purl.uniprot.org/uniprot/M4VQA6 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1184267:A11Q_RS10090 ^@ http://purl.uniprot.org/uniprot/M4VAG5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS05845 ^@ http://purl.uniprot.org/uniprot/M4VA85 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/1184267:A11Q_RS04325 ^@ http://purl.uniprot.org/uniprot/M4V7A3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS00250 ^@ http://purl.uniprot.org/uniprot/M4V8E1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS04520 ^@ http://purl.uniprot.org/uniprot/M4VAR9 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1184267:A11Q_RS00055 ^@ http://purl.uniprot.org/uniprot/M4V8A6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1184267:A11Q_RS10790 ^@ http://purl.uniprot.org/uniprot/M4VAV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1184267:A11Q_RS07535 ^@ http://purl.uniprot.org/uniprot/M4V922 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1184267:A11Q_RS13505 ^@ http://purl.uniprot.org/uniprot/M4V8J0 ^@ Function|||Similarity ^@ Belongs to the LipB family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. http://togogenome.org/gene/1184267:A11Q_RS09585 ^@ http://purl.uniprot.org/uniprot/M4V9Q0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1184267:A11Q_RS11215 ^@ http://purl.uniprot.org/uniprot/M4VD77 ^@ Function ^@ Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/1184267:A11Q_RS12850 ^@ http://purl.uniprot.org/uniprot/M4VC01 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1184267:A11Q_RS11900 ^@ http://purl.uniprot.org/uniprot/M4VEW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS08160 ^@ http://purl.uniprot.org/uniprot/M4VCS5 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1184267:A11Q_RS02645 ^@ http://purl.uniprot.org/uniprot/M4V8G1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1184267:A11Q_RS07760 ^@ http://purl.uniprot.org/uniprot/M4V961 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1184267:A11Q_RS07190 ^@ http://purl.uniprot.org/uniprot/M4V8V6 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1184267:A11Q_RS00620 ^@ http://purl.uniprot.org/uniprot/M4V8K8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1184267:A11Q_RS13070 ^@ http://purl.uniprot.org/uniprot/M4VC47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 5 family.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS08920 ^@ http://purl.uniprot.org/uniprot/M4VBZ9 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1184267:A11Q_RS04575 ^@ http://purl.uniprot.org/uniprot/M4V6X5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1184267:A11Q_RS04255 ^@ http://purl.uniprot.org/uniprot/M4VPL6 ^@ Function|||Similarity ^@ Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.|||Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. http://togogenome.org/gene/1184267:A11Q_RS02255 ^@ http://purl.uniprot.org/uniprot/M4V5N6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02720 ^@ http://purl.uniprot.org/uniprot/M4V8H5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS03050 ^@ http://purl.uniprot.org/uniprot/M4V638 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1184267:A11Q_RS09750 ^@ http://purl.uniprot.org/uniprot/M4VCE2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1184267:A11Q_RS02390 ^@ http://purl.uniprot.org/uniprot/M4V8C1 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/1184267:A11Q_RS10185 ^@ http://purl.uniprot.org/uniprot/M4VA05 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1184267:A11Q_RS13135 ^@ http://purl.uniprot.org/uniprot/M4VFJ4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1184267:A11Q_RS02360 ^@ http://purl.uniprot.org/uniprot/M4VNL2 ^@ Cofactor|||Similarity ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1184267:A11Q_RS09620 ^@ http://purl.uniprot.org/uniprot/M4VSF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1184267:A11Q_RS00015 ^@ http://purl.uniprot.org/uniprot/M4V4X0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1184267:A11Q_RS07005 ^@ http://purl.uniprot.org/uniprot/M4V898 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/1184267:A11Q_RS08410 ^@ http://purl.uniprot.org/uniprot/M4V907 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/1184267:A11Q_RS09525 ^@ http://purl.uniprot.org/uniprot/M4VCA3 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1184267:A11Q_RS02080 ^@ http://purl.uniprot.org/uniprot/M4V626 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1184267:A11Q_RS03630 ^@ http://purl.uniprot.org/uniprot/M4VP84 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer.