http://togogenome.org/gene/1167006:UWK_RS09480 ^@ http://purl.uniprot.org/uniprot/M1NFN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS13275 ^@ http://purl.uniprot.org/uniprot/M1NHZ3 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/1167006:UWK_RS06570 ^@ http://purl.uniprot.org/uniprot/M1PN62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05560 ^@ http://purl.uniprot.org/uniprot/M1P7K8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1167006:UWK_RS16330 ^@ http://purl.uniprot.org/uniprot/M1NJR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS10225 ^@ http://purl.uniprot.org/uniprot/M1PG01 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS17 family.|||One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS04290 ^@ http://purl.uniprot.org/uniprot/M1PCF7 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1167006:UWK_RS04170 ^@ http://purl.uniprot.org/uniprot/M1PCD3 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). http://togogenome.org/gene/1167006:UWK_RS10045 ^@ http://purl.uniprot.org/uniprot/M1NFY7 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1167006:UWK_RS17125 ^@ http://purl.uniprot.org/uniprot/M1NK69 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1167006:UWK_RS09160 ^@ http://purl.uniprot.org/uniprot/M1NFF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS10280 ^@ http://purl.uniprot.org/uniprot/M1PG11 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1167006:UWK_RS01205 ^@ http://purl.uniprot.org/uniprot/M1NZX1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS16665 ^@ http://purl.uniprot.org/uniprot/M1P8T0 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1167006:UWK_RS12465 ^@ http://purl.uniprot.org/uniprot/M1PBP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1167006:UWK_RS17705 ^@ http://purl.uniprot.org/uniprot/M1NKG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS04165 ^@ http://purl.uniprot.org/uniprot/M1NC93 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/1167006:UWK_RS08135 ^@ http://purl.uniprot.org/uniprot/M1PEQ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1167006:UWK_RS05800 ^@ http://purl.uniprot.org/uniprot/M1PMQ8 ^@ Similarity ^@ Belongs to the peptidase A31 family. http://togogenome.org/gene/1167006:UWK_RS17520 ^@ http://purl.uniprot.org/uniprot/M1NKE0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1167006:UWK_RS07480 ^@ http://purl.uniprot.org/uniprot/M1NEE0 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1167006:UWK_RS00210 ^@ http://purl.uniprot.org/uniprot/M1PA06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS08030 ^@ http://purl.uniprot.org/uniprot/M1NEP0 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1167006:UWK_RS01165 ^@ http://purl.uniprot.org/uniprot/M1PAJ5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS10105 ^@ http://purl.uniprot.org/uniprot/M1PAB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1167006:UWK_RS08425 ^@ http://purl.uniprot.org/uniprot/M1P442 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS16115 ^@ http://purl.uniprot.org/uniprot/M1PJP2 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1167006:UWK_RS17815 ^@ http://purl.uniprot.org/uniprot/M1NKI4 ^@ Similarity ^@ Belongs to the HsdR family. http://togogenome.org/gene/1167006:UWK_RS14470 ^@ http://purl.uniprot.org/uniprot/M1PT08 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS13770 ^@ http://purl.uniprot.org/uniprot/M1P754 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1167006:UWK_RS16935 ^@ http://purl.uniprot.org/uniprot/M1PED1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1167006:UWK_RS05630 ^@ http://purl.uniprot.org/uniprot/M1PMM1 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1167006:UWK_RS05145 ^@ http://purl.uniprot.org/uniprot/M1NCX3 ^@ Function|||Similarity ^@ Belongs to the acetyltransferase family. EctA subfamily.|||Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A. http://togogenome.org/gene/1167006:UWK_RS01955 ^@ http://purl.uniprot.org/uniprot/M1PB47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS04520 ^@ http://purl.uniprot.org/uniprot/M1P1X3 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS07440 ^@ http://purl.uniprot.org/uniprot/M1PNR8 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1167006:UWK_RS02320 ^@ http://purl.uniprot.org/uniprot/M1PBB5 ^@ Function|||Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate. http://togogenome.org/gene/1167006:UWK_RS02740 ^@ http://purl.uniprot.org/uniprot/M1P609 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00860 ^@ http://purl.uniprot.org/uniprot/M1P4W7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS17895 ^@ http://purl.uniprot.org/uniprot/M1NKK0 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1167006:UWK_RS04490 ^@ http://purl.uniprot.org/uniprot/M1P701 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS03005 ^@ http://purl.uniprot.org/uniprot/M1P0X2 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS17360 ^@ http://purl.uniprot.org/uniprot/M1PUL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS07625 ^@ http://purl.uniprot.org/uniprot/M1P3P7 ^@ Function|||Similarity ^@ Belongs to the PhnJ family.|||Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose. http://togogenome.org/gene/1167006:UWK_RS16850 ^@ http://purl.uniprot.org/uniprot/M1PK49 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS11170 ^@ http://purl.uniprot.org/uniprot/M1P5L7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the adenylate cyclase family. DacA/CdaA subfamily.|||Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Probably a homodimer. http://togogenome.org/gene/1167006:UWK_RS03995 ^@ http://purl.uniprot.org/uniprot/M1P6N1 ^@ Similarity ^@ Belongs to the SfsA family. http://togogenome.org/gene/1167006:UWK_RS17670 ^@ http://purl.uniprot.org/uniprot/M1PEV2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1167006:UWK_RS01000 ^@ http://purl.uniprot.org/uniprot/M1NAA2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1167006:UWK_RS17875 ^@ http://purl.uniprot.org/uniprot/M1PKS6 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS17445 ^@ http://purl.uniprot.org/uniprot/M1NKC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09085 ^@ http://purl.uniprot.org/uniprot/M1P4H1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS03050 ^@ http://purl.uniprot.org/uniprot/M1P663 ^@ Cofactor|||Similarity ^@ Belongs to the RimK family.|||Binds 2 magnesium or manganese ions per subunit. http://togogenome.org/gene/1167006:UWK_RS13010 ^@ http://purl.uniprot.org/uniprot/M1PC02 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS06810 ^@ http://purl.uniprot.org/uniprot/M1PE03 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1167006:UWK_RS04245 ^@ http://purl.uniprot.org/uniprot/M1PCE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS10150 ^@ http://purl.uniprot.org/uniprot/M1PFY7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1167006:UWK_RS02680 ^@ http://purl.uniprot.org/uniprot/M1PKV4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1167006:UWK_RS10530 ^@ http://purl.uniprot.org/uniprot/M1PG69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase Y family.|||Cell membrane|||Endoribonuclease that initiates mRNA decay. http://togogenome.org/gene/1167006:UWK_RS16045 ^@ http://purl.uniprot.org/uniprot/M1PTT0 ^@ Cofactor|||Similarity ^@ Belongs to the PTPS family. QueD subfamily.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1167006:UWK_RS12080 ^@ http://purl.uniprot.org/uniprot/M1P6C4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS17700 ^@ http://purl.uniprot.org/uniprot/M1P9F7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS02180 ^@ http://purl.uniprot.org/uniprot/M1P5R9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS06690 ^@ http://purl.uniprot.org/uniprot/M1P8B4 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1167006:UWK_RS07025 ^@ http://purl.uniprot.org/uniprot/M1PE55 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SurE nucleotidase family.|||Binds 1 divalent metal cation per subunit.|||Cytoplasm|||Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates. http://togogenome.org/gene/1167006:UWK_RS12845 ^@ http://purl.uniprot.org/uniprot/M1P6P4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. http://togogenome.org/gene/1167006:UWK_RS01765 ^@ http://purl.uniprot.org/uniprot/M1P5H7 ^@ Function|||Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family.|||This protein may play a role in the biosynthesis of the prosthetic group of nitrogenase (FeMo cofactor). http://togogenome.org/gene/1167006:UWK_RS08300 ^@ http://purl.uniprot.org/uniprot/M1P416 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1167006:UWK_RS00075 ^@ http://purl.uniprot.org/uniprot/M1P9Y7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1167006:UWK_RS11660 ^@ http://purl.uniprot.org/uniprot/M1PB66 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS16550 ^@ http://purl.uniprot.org/uniprot/M1PE49 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1167006:UWK_RS14645 ^@ http://purl.uniprot.org/uniprot/M1PD11 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1167006:UWK_RS18025 ^@ http://purl.uniprot.org/uniprot/M1NZY7 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1167006:UWK_RS07365 ^@ http://purl.uniprot.org/uniprot/M1PNQ5 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1167006:UWK_RS13565 ^@ http://purl.uniprot.org/uniprot/M1PSE2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the radical SAM superfamily. MqnC family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1167006:UWK_RS00050 ^@ http://purl.uniprot.org/uniprot/M1P9Y5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1167006:UWK_RS05010 ^@ http://purl.uniprot.org/uniprot/M1P264 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05160 ^@ http://purl.uniprot.org/uniprot/M1NCX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS11530 ^@ http://purl.uniprot.org/uniprot/M1PR51 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1167006:UWK_RS03425 ^@ http://purl.uniprot.org/uniprot/M1PBW3 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1167006:UWK_RS14950 ^@ http://purl.uniprot.org/uniprot/M1P7U9 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1167006:UWK_RS02455 ^@ http://purl.uniprot.org/uniprot/M1PKR4 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1167006:UWK_RS03490 ^@ http://purl.uniprot.org/uniprot/M1P161 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1167006:UWK_RS12410 ^@ http://purl.uniprot.org/uniprot/M1PRR8 ^@ Caution|||Function|||Similarity ^@ Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1167006:UWK_RS10870 ^@ http://purl.uniprot.org/uniprot/M1P5F9 ^@ Function|||Similarity|||Subunit ^@ Associates with the 50S ribosomal subunit.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.|||GTPase that plays an essential role in the late steps of ribosome biogenesis. http://togogenome.org/gene/1167006:UWK_RS18360 ^@ http://purl.uniprot.org/uniprot/M1P3L2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS04875 ^@ http://purl.uniprot.org/uniprot/M1PCT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1167006:UWK_RS07095 ^@ http://purl.uniprot.org/uniprot/M1PNK5 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1167006:UWK_RS15710 ^@ http://purl.uniprot.org/uniprot/M1P882 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1167006:UWK_RS07700 ^@ http://purl.uniprot.org/uniprot/M1P3Q9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS13270 ^@ http://purl.uniprot.org/uniprot/M1P6W8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1167006:UWK_RS13595 ^@ http://purl.uniprot.org/uniprot/M1PCC9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS00595 ^@ http://purl.uniprot.org/uniprot/M1NA21 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS02580 ^@ http://purl.uniprot.org/uniprot/M1P0Q6 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS10260 ^@ http://purl.uniprot.org/uniprot/M1PQD2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1167006:UWK_RS04435 ^@ http://purl.uniprot.org/uniprot/M1PCI9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS17790 ^@ http://purl.uniprot.org/uniprot/M1NKH9 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1167006:UWK_RS08055 ^@ http://purl.uniprot.org/uniprot/M1NEP4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16140 ^@ http://purl.uniprot.org/uniprot/M1PTV4 ^@ Function ^@ Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. http://togogenome.org/gene/1167006:UWK_RS12650 ^@ http://purl.uniprot.org/uniprot/M1P6L2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family.|||Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer and homodimer. http://togogenome.org/gene/1167006:UWK_RS11035 ^@ http://purl.uniprot.org/uniprot/M1PQT5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PNT beta subunit family.|||Cell inner membrane|||Membrane|||The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1167006:UWK_RS16295 ^@ http://purl.uniprot.org/uniprot/M1PE02 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/1167006:UWK_RS02965 ^@ http://purl.uniprot.org/uniprot/M1NBI3 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS16395 ^@ http://purl.uniprot.org/uniprot/M1PE22 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05060 ^@ http://purl.uniprot.org/uniprot/M1P7B5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS16835 ^@ http://purl.uniprot.org/uniprot/M1PUA7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS03980 ^@ http://purl.uniprot.org/uniprot/M1NC50 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS08480 ^@ http://purl.uniprot.org/uniprot/M1NEZ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1167006:UWK_RS01040 ^@ http://purl.uniprot.org/uniprot/M1P503 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1167006:UWK_RS01895 ^@ http://purl.uniprot.org/uniprot/M1P0D1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transglycosylase MltG family.|||Cell inner membrane|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1167006:UWK_RS14715 ^@ http://purl.uniprot.org/uniprot/M1PD20 ^@ Similarity ^@ Belongs to the prephenate/arogenate dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS12785 ^@ http://purl.uniprot.org/uniprot/M1PRY4 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1167006:UWK_RS05795 ^@ http://purl.uniprot.org/uniprot/M1PDA3 ^@ Similarity ^@ Belongs to the HypE family. http://togogenome.org/gene/1167006:UWK_RS08005 ^@ http://purl.uniprot.org/uniprot/M1NEN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1167006:UWK_RS10175 ^@ http://purl.uniprot.org/uniprot/M1PFZ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS00070 ^@ http://purl.uniprot.org/uniprot/M1N9S1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1167006:UWK_RS01830 ^@ http://purl.uniprot.org/uniprot/M1PB03 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1167006:UWK_RS11485 ^@ http://purl.uniprot.org/uniprot/M1PB28 ^@ Function|||Similarity|||Subunit ^@ Belongs to the MoaC family.|||Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).|||Homohexamer; trimer of dimers. http://togogenome.org/gene/1167006:UWK_RS12620 ^@ http://purl.uniprot.org/uniprot/M1PBS6 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS10310 ^@ http://purl.uniprot.org/uniprot/M1PAE2 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1167006:UWK_RS08060 ^@ http://purl.uniprot.org/uniprot/M1PEN7 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1167006:UWK_RS04870 ^@ http://purl.uniprot.org/uniprot/M1NCS5 ^@ Function|||Similarity ^@ Belongs to the ATPase gamma chain family.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1167006:UWK_RS13890 ^@ http://purl.uniprot.org/uniprot/M1PSM0 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1167006:UWK_RS17090 ^@ http://purl.uniprot.org/uniprot/M1P931 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS11130 ^@ http://purl.uniprot.org/uniprot/M1PGK6 ^@ Similarity ^@ Belongs to the MEMO1 family. http://togogenome.org/gene/1167006:UWK_RS10455 ^@ http://purl.uniprot.org/uniprot/M1PQG9 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1167006:UWK_RS14460 ^@ http://purl.uniprot.org/uniprot/M1NIQ6 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1167006:UWK_RS06205 ^@ http://purl.uniprot.org/uniprot/M1PDK5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1167006:UWK_RS04265 ^@ http://purl.uniprot.org/uniprot/M1PCF2 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1167006:UWK_RS12795 ^@ http://purl.uniprot.org/uniprot/M1P6N3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1167006:UWK_RS14465 ^@ http://purl.uniprot.org/uniprot/M1PIM9 ^@ Similarity ^@ Belongs to the TrpC family. http://togogenome.org/gene/1167006:UWK_RS08825 ^@ http://purl.uniprot.org/uniprot/M1P9J9 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1167006:UWK_RS00250 ^@ http://purl.uniprot.org/uniprot/M1NZF1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1167006:UWK_RS16900 ^@ http://purl.uniprot.org/uniprot/M1PK63 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1167006:UWK_RS14390 ^@ http://purl.uniprot.org/uniprot/M1PSY8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS15530 ^@ http://purl.uniprot.org/uniprot/M1P852 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1167006:UWK_RS02620 ^@ http://purl.uniprot.org/uniprot/M1NBC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1167006:UWK_RS14075 ^@ http://purl.uniprot.org/uniprot/M1NIH4 ^@ Similarity ^@ Belongs to the CutA family. http://togogenome.org/gene/1167006:UWK_RS10440 ^@ http://purl.uniprot.org/uniprot/M1NG59 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1167006:UWK_RS06660 ^@ http://purl.uniprot.org/uniprot/M1PDW8 ^@ Cofactor ^@ Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1167006:UWK_RS04060 ^@ http://purl.uniprot.org/uniprot/M1PCA9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1167006:UWK_RS02040 ^@ http://purl.uniprot.org/uniprot/M1PB68 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS11555 ^@ http://purl.uniprot.org/uniprot/M1PR57 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1167006:UWK_RS09315 ^@ http://purl.uniprot.org/uniprot/M1PFI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14485 ^@ http://purl.uniprot.org/uniprot/M1NIR1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1167006:UWK_RS17340 ^@ http://purl.uniprot.org/uniprot/M1PEP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1167006:UWK_RS13735 ^@ http://purl.uniprot.org/uniprot/M1P749 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1167006:UWK_RS03435 ^@ http://purl.uniprot.org/uniprot/M1P6B7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1167006:UWK_RS04510 ^@ http://purl.uniprot.org/uniprot/M1PM10 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS03630 ^@ http://purl.uniprot.org/uniprot/M1PLE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS10955 ^@ http://purl.uniprot.org/uniprot/M1PGG8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Mrp/NBP35 ATP-binding proteins family.|||Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03975 ^@ http://purl.uniprot.org/uniprot/M1P1H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1167006:UWK_RS09205 ^@ http://purl.uniprot.org/uniprot/M1P4K2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1167006:UWK_RS16090 ^@ http://purl.uniprot.org/uniprot/M1PJN6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16890 ^@ http://purl.uniprot.org/uniprot/M1P8Y4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS16495 ^@ http://purl.uniprot.org/uniprot/M1PE39 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16625 ^@ http://purl.uniprot.org/uniprot/M1PJZ3 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1167006:UWK_RS02175 ^@ http://purl.uniprot.org/uniprot/M1PKL4 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1167006:UWK_RS05615 ^@ http://purl.uniprot.org/uniprot/M1P2H8 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/1167006:UWK_RS05810 ^@ http://purl.uniprot.org/uniprot/M1P2L9 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily. http://togogenome.org/gene/1167006:UWK_RS14060 ^@ http://purl.uniprot.org/uniprot/M1PSR5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the gmhB family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS11935 ^@ http://purl.uniprot.org/uniprot/M1NH56 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08445 ^@ http://purl.uniprot.org/uniprot/M1P9B7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS07995 ^@ http://purl.uniprot.org/uniprot/M1P925 ^@ Cofactor|||Similarity ^@ Belongs to the monomeric-type IDH family.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit. http://togogenome.org/gene/1167006:UWK_RS04375 ^@ http://purl.uniprot.org/uniprot/M1P1S7 ^@ Similarity ^@ Belongs to the serine/threonine dehydratase family. http://togogenome.org/gene/1167006:UWK_RS12415 ^@ http://purl.uniprot.org/uniprot/M1PBP1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS03585 ^@ http://purl.uniprot.org/uniprot/M1P6E1 ^@ Similarity ^@ Belongs to the pyruvate kinase family.|||In the C-terminal section; belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1167006:UWK_RS10500 ^@ http://purl.uniprot.org/uniprot/M1PG63 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/1167006:UWK_RS04890 ^@ http://purl.uniprot.org/uniprot/M1P244 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1167006:UWK_RS12505 ^@ http://purl.uniprot.org/uniprot/M1PHH9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS17585 ^@ http://purl.uniprot.org/uniprot/M1PET7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS13600 ^@ http://purl.uniprot.org/uniprot/M1P727 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1167006:UWK_RS17265 ^@ http://purl.uniprot.org/uniprot/M1PEM8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1167006:UWK_RS13035 ^@ http://purl.uniprot.org/uniprot/M1PC07 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. MoaA family.|||Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.|||Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.|||Monomer and homodimer. http://togogenome.org/gene/1167006:UWK_RS10120 ^@ http://purl.uniprot.org/uniprot/M1NFZ5 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1167006:UWK_RS05765 ^@ http://purl.uniprot.org/uniprot/M1ND85 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.|||Heterodimer of a large and a small subunit.|||Periplasm http://togogenome.org/gene/1167006:UWK_RS17480 ^@ http://purl.uniprot.org/uniprot/M1PUP1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endonuclease Cas1 family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas2 homodimer. http://togogenome.org/gene/1167006:UWK_RS00105 ^@ http://purl.uniprot.org/uniprot/M1N9S5 ^@ Similarity ^@ Belongs to the type IA topoisomerase family. http://togogenome.org/gene/1167006:UWK_RS03785 ^@ http://purl.uniprot.org/uniprot/M1NC06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14640 ^@ http://purl.uniprot.org/uniprot/M1PT52 ^@ Similarity ^@ Belongs to the CobH/CbiC family. http://togogenome.org/gene/1167006:UWK_RS13885 ^@ http://purl.uniprot.org/uniprot/M1PIA8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS05445 ^@ http://purl.uniprot.org/uniprot/M1P7I8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1167006:UWK_RS03790 ^@ http://purl.uniprot.org/uniprot/M1PC50 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1167006:UWK_RS11925 ^@ http://purl.uniprot.org/uniprot/M1PBD2 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/1167006:UWK_RS05310 ^@ http://purl.uniprot.org/uniprot/M1P2C3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RlmKL family.|||Cytoplasm|||Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA. http://togogenome.org/gene/1167006:UWK_RS02440 ^@ http://purl.uniprot.org/uniprot/M1P0N3 ^@ Function|||Similarity ^@ Belongs to the RmuC family.|||Involved in DNA recombination. http://togogenome.org/gene/1167006:UWK_RS07840 ^@ http://purl.uniprot.org/uniprot/M1P901 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1167006:UWK_RS00735 ^@ http://purl.uniprot.org/uniprot/M1P4U4 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1167006:UWK_RS17455 ^@ http://purl.uniprot.org/uniprot/M1PUN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1167006:UWK_RS09415 ^@ http://purl.uniprot.org/uniprot/M1PFK8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ThiG family.|||Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.|||Cytoplasm|||Homotetramer. Forms heterodimers with either ThiH or ThiS. http://togogenome.org/gene/1167006:UWK_RS08280 ^@ http://purl.uniprot.org/uniprot/M1NEU0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1167006:UWK_RS09400 ^@ http://purl.uniprot.org/uniprot/M1P9Y4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS08970 ^@ http://purl.uniprot.org/uniprot/M1P9N0 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1167006:UWK_RS17570 ^@ http://purl.uniprot.org/uniprot/M1NKE6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. http://togogenome.org/gene/1167006:UWK_RS08230 ^@ http://purl.uniprot.org/uniprot/M1NES8 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1167006:UWK_RS11610 ^@ http://purl.uniprot.org/uniprot/M1P5X9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S49 family.|||Cell inner membrane http://togogenome.org/gene/1167006:UWK_RS02590 ^@ http://purl.uniprot.org/uniprot/M1PBF8 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1167006:UWK_RS09065 ^@ http://purl.uniprot.org/uniprot/M1NFD7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS11950 ^@ http://purl.uniprot.org/uniprot/M1PBD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS11645 ^@ http://purl.uniprot.org/uniprot/M1NGY7 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1167006:UWK_RS08180 ^@ http://purl.uniprot.org/uniprot/M1NER7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1167006:UWK_RS08615 ^@ http://purl.uniprot.org/uniprot/M1PPD9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS07990 ^@ http://purl.uniprot.org/uniprot/M1PP17 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1167006:UWK_RS13040 ^@ http://purl.uniprot.org/uniprot/M1P6S9 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS17215 ^@ http://purl.uniprot.org/uniprot/M1PEL8 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1167006:UWK_RS17640 ^@ http://purl.uniprot.org/uniprot/M1PUR8 ^@ Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS04795 ^@ http://purl.uniprot.org/uniprot/M1PCR9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DEAD box helicase family. RhlB subfamily.|||Cytoplasm|||DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA. http://togogenome.org/gene/1167006:UWK_RS02900 ^@ http://purl.uniprot.org/uniprot/M1P637 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1167006:UWK_RS15385 ^@ http://purl.uniprot.org/uniprot/M1NJ99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgH family.|||Cell outer membrane|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1167006:UWK_RS02010 ^@ http://purl.uniprot.org/uniprot/M1PKI5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.|||Belongs to the helicase family. UvrD subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.|||The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.|||The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC. http://togogenome.org/gene/1167006:UWK_RS03430 ^@ http://purl.uniprot.org/uniprot/M1PL96 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1167006:UWK_RS12285 ^@ http://purl.uniprot.org/uniprot/M1PHD6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00555 ^@ http://purl.uniprot.org/uniprot/M1PJL6 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1167006:UWK_RS15780 ^@ http://purl.uniprot.org/uniprot/M1PDN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS15405 ^@ http://purl.uniprot.org/uniprot/M1P831 ^@ Function|||Similarity ^@ Belongs to the FlgM family.|||Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA. http://togogenome.org/gene/1167006:UWK_RS15305 ^@ http://purl.uniprot.org/uniprot/M1P814 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell inner membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1167006:UWK_RS14130 ^@ http://purl.uniprot.org/uniprot/M1PST4 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/1167006:UWK_RS15295 ^@ http://purl.uniprot.org/uniprot/M1PTF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MotA family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS16105 ^@ http://purl.uniprot.org/uniprot/M1P8G3 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1167006:UWK_RS14385 ^@ http://purl.uniprot.org/uniprot/M1PIL1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS16340 ^@ http://purl.uniprot.org/uniprot/M1PU01 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1167006:UWK_RS03960 ^@ http://purl.uniprot.org/uniprot/M1PLL9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS09010 ^@ http://purl.uniprot.org/uniprot/M1NFC4 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/1167006:UWK_RS17390 ^@ http://purl.uniprot.org/uniprot/M1PEQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1167006:UWK_RS08505 ^@ http://purl.uniprot.org/uniprot/M1NF00 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1167006:UWK_RS13925 ^@ http://purl.uniprot.org/uniprot/M1P780 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1167006:UWK_RS01655 ^@ http://purl.uniprot.org/uniprot/M1P503 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1167006:UWK_RS07300 ^@ http://purl.uniprot.org/uniprot/M1P3J2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS18515 ^@ http://purl.uniprot.org/uniprot/M1PQ52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS07355 ^@ http://purl.uniprot.org/uniprot/M1NEC2 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1167006:UWK_RS16255 ^@ http://purl.uniprot.org/uniprot/M1P8J2 ^@ Function|||Subcellular Location Annotation ^@ Cell inner membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system. http://togogenome.org/gene/1167006:UWK_RS16310 ^@ http://purl.uniprot.org/uniprot/M1PJT4 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1167006:UWK_RS14010 ^@ http://purl.uniprot.org/uniprot/M1PSQ3 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS08745 ^@ http://purl.uniprot.org/uniprot/M1P9I3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the FPG family.|||Binds 1 zinc ion per subunit.|||Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS16975 ^@ http://purl.uniprot.org/uniprot/M1PK86 ^@ Similarity ^@ Belongs to the UPF0251 family. http://togogenome.org/gene/1167006:UWK_RS12160 ^@ http://purl.uniprot.org/uniprot/M1NHB4 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1167006:UWK_RS02625 ^@ http://purl.uniprot.org/uniprot/M1PBG1 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1167006:UWK_RS08780 ^@ http://purl.uniprot.org/uniprot/M1NF68 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1167006:UWK_RS01585 ^@ http://purl.uniprot.org/uniprot/M1PK62 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1167006:UWK_RS04110 ^@ http://purl.uniprot.org/uniprot/M1P6Q7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1167006:UWK_RS10875 ^@ http://purl.uniprot.org/uniprot/M1NGF0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05090 ^@ http://purl.uniprot.org/uniprot/M1P279 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/1167006:UWK_RS00495 ^@ http://purl.uniprot.org/uniprot/M1PA55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS11340 ^@ http://purl.uniprot.org/uniprot/M1P5P8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS11080 ^@ http://purl.uniprot.org/uniprot/M1PQU6 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1167006:UWK_RS13745 ^@ http://purl.uniprot.org/uniprot/M1PI82 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1167006:UWK_RS04560 ^@ http://purl.uniprot.org/uniprot/M1PCN3 ^@ Similarity ^@ Belongs to the tRNA methyltransferase O family. http://togogenome.org/gene/1167006:UWK_RS03275 ^@ http://purl.uniprot.org/uniprot/M1P698 ^@ Similarity ^@ Belongs to the HipA Ser/Thr kinase family. http://togogenome.org/gene/1167006:UWK_RS10265 ^@ http://purl.uniprot.org/uniprot/M1PAD3 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1167006:UWK_RS14530 ^@ http://purl.uniprot.org/uniprot/M1PCY0 ^@ Function|||Similarity ^@ Belongs to the GTP cyclohydrolase IV family.|||Converts GTP to 7,8-dihydroneopterin triphosphate. http://togogenome.org/gene/1167006:UWK_RS05790 ^@ http://purl.uniprot.org/uniprot/M1ND90 ^@ Similarity ^@ Belongs to the HypD family. http://togogenome.org/gene/1167006:UWK_RS05415 ^@ http://purl.uniprot.org/uniprot/M1PD16 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1167006:UWK_RS08875 ^@ http://purl.uniprot.org/uniprot/M1P4C5 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1167006:UWK_RS17145 ^@ http://purl.uniprot.org/uniprot/M1P951 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04240 ^@ http://purl.uniprot.org/uniprot/M1NCB5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS00110 ^@ http://purl.uniprot.org/uniprot/M1P9Z1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1167006:UWK_RS11140 ^@ http://purl.uniprot.org/uniprot/M1PAV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS03460 ^@ http://purl.uniprot.org/uniprot/M1P6B9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the argininosuccinate synthase family. Type 1 subfamily.|||Cytoplasm|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS12790 ^@ http://purl.uniprot.org/uniprot/M1PBV7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1167006:UWK_RS16960 ^@ http://purl.uniprot.org/uniprot/M1PED6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS11675 ^@ http://purl.uniprot.org/uniprot/M1PR88 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1167006:UWK_RS02595 ^@ http://purl.uniprot.org/uniprot/M1PKU0 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1167006:UWK_RS08655 ^@ http://purl.uniprot.org/uniprot/M1NF39 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS05550 ^@ http://purl.uniprot.org/uniprot/M1PD40 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1167006:UWK_RS11780 ^@ http://purl.uniprot.org/uniprot/M1PB95 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS00550 ^@ http://purl.uniprot.org/uniprot/M1PA66 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1167006:UWK_RS04705 ^@ http://purl.uniprot.org/uniprot/M1PM55 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1167006:UWK_RS16515 ^@ http://purl.uniprot.org/uniprot/M1PU37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1167006:UWK_RS05390 ^@ http://purl.uniprot.org/uniprot/M1PD14 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1167006:UWK_RS10305 ^@ http://purl.uniprot.org/uniprot/M1PQE2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1167006:UWK_RS03470 ^@ http://purl.uniprot.org/uniprot/M1NBS8 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1167006:UWK_RS09090 ^@ http://purl.uniprot.org/uniprot/M1PFC7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1167006:UWK_RS11020 ^@ http://purl.uniprot.org/uniprot/M1P5I8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1167006:UWK_RS17410 ^@ http://purl.uniprot.org/uniprot/M1PUM8 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS07975 ^@ http://purl.uniprot.org/uniprot/M1P3V3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamA family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1167006:UWK_RS01395 ^@ http://purl.uniprot.org/uniprot/M1PAP6 ^@ Similarity ^@ Belongs to the 4-oxalocrotonate tautomerase family. http://togogenome.org/gene/1167006:UWK_RS01195 ^@ http://purl.uniprot.org/uniprot/M1PJY0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1167006:UWK_RS07295 ^@ http://purl.uniprot.org/uniprot/M1P8Q9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS08485 ^@ http://purl.uniprot.org/uniprot/M1PEY5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1167006:UWK_RS13910 ^@ http://purl.uniprot.org/uniprot/M1PIB4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1167006:UWK_RS17530 ^@ http://purl.uniprot.org/uniprot/M1PUP9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS06585 ^@ http://purl.uniprot.org/uniprot/M1NDT4 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1167006:UWK_RS16985 ^@ http://purl.uniprot.org/uniprot/M1PEE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS10950 ^@ http://purl.uniprot.org/uniprot/M1NGG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1167006:UWK_RS06695 ^@ http://purl.uniprot.org/uniprot/M1P363 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS10920 ^@ http://purl.uniprot.org/uniprot/M1P5G8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS01775 ^@ http://purl.uniprot.org/uniprot/M1NAT5 ^@ Similarity ^@ Belongs to the radical SAM superfamily. NifB family. http://togogenome.org/gene/1167006:UWK_RS15555 ^@ http://purl.uniprot.org/uniprot/M1P857 ^@ Function|||Similarity ^@ Belongs to the MoaB/Mog family.|||May be involved in the biosynthesis of molybdopterin. http://togogenome.org/gene/1167006:UWK_RS07715 ^@ http://purl.uniprot.org/uniprot/M1P8Y1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16575 ^@ http://purl.uniprot.org/uniprot/M1PU49 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1167006:UWK_RS06665 ^@ http://purl.uniprot.org/uniprot/M1PN88 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1167006:UWK_RS12125 ^@ http://purl.uniprot.org/uniprot/M1P6D0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS07785 ^@ http://purl.uniprot.org/uniprot/M1PNX6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1167006:UWK_RS13935 ^@ http://purl.uniprot.org/uniprot/M1PIC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS13515 ^@ http://purl.uniprot.org/uniprot/M1P714 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1167006:UWK_RS15550 ^@ http://purl.uniprot.org/uniprot/M1PDJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10485 ^@ http://purl.uniprot.org/uniprot/M1PAH5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS00135 ^@ http://purl.uniprot.org/uniprot/M1P9Z5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1167006:UWK_RS02090 ^@ http://purl.uniprot.org/uniprot/M1PB78 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS07585 ^@ http://purl.uniprot.org/uniprot/M1PEE5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS08490 ^@ http://purl.uniprot.org/uniprot/M1PPB4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1167006:UWK_RS16400 ^@ http://purl.uniprot.org/uniprot/M1P8M2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1167006:UWK_RS07865 ^@ http://purl.uniprot.org/uniprot/M1P904 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1167006:UWK_RS13580 ^@ http://purl.uniprot.org/uniprot/M1NI66 ^@ Caution|||Function|||Similarity ^@ Belongs to the UbiX/PAD1 family.|||Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS14560 ^@ http://purl.uniprot.org/uniprot/M1P7M8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1167006:UWK_RS13465 ^@ http://purl.uniprot.org/uniprot/M1PCA2 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS09620 ^@ http://purl.uniprot.org/uniprot/M1PQ39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1167006:UWK_RS14780 ^@ http://purl.uniprot.org/uniprot/M1NJ00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS01670 ^@ http://purl.uniprot.org/uniprot/M1NAQ8 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1167006:UWK_RS10670 ^@ http://purl.uniprot.org/uniprot/M1P5B9 ^@ Function|||Similarity ^@ Belongs to the MqnA/MqnD family. MqnD subfamily.|||Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). http://togogenome.org/gene/1167006:UWK_RS09180 ^@ http://purl.uniprot.org/uniprot/M1P4J6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS07090 ^@ http://purl.uniprot.org/uniprot/M1PE75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS02055 ^@ http://purl.uniprot.org/uniprot/M1P0H8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS07000 ^@ http://purl.uniprot.org/uniprot/M1PE42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS07605 ^@ http://purl.uniprot.org/uniprot/M1NEF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS11725 ^@ http://purl.uniprot.org/uniprot/M1PRA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS01365 ^@ http://purl.uniprot.org/uniprot/M1PAP1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS11135 ^@ http://purl.uniprot.org/uniprot/M1PQV6 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS03105 ^@ http://purl.uniprot.org/uniprot/M1P0Z0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial glucokinase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15420 ^@ http://purl.uniprot.org/uniprot/M1PTH2 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1167006:UWK_RS08675 ^@ http://purl.uniprot.org/uniprot/M1P486 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/1167006:UWK_RS02930 ^@ http://purl.uniprot.org/uniprot/M1P642 ^@ Function|||Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily.|||Catalyzes the biosynthesis of agmatine from arginine. http://togogenome.org/gene/1167006:UWK_RS07505 ^@ http://purl.uniprot.org/uniprot/M1NEE5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1167006:UWK_RS08990 ^@ http://purl.uniprot.org/uniprot/M1PPM9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS17290 ^@ http://purl.uniprot.org/uniprot/M1PEN3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS13215 ^@ http://purl.uniprot.org/uniprot/M1P6W0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.|||Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS04055 ^@ http://purl.uniprot.org/uniprot/M1NC67 ^@ Similarity ^@ Belongs to the SecB family. http://togogenome.org/gene/1167006:UWK_RS05350 ^@ http://purl.uniprot.org/uniprot/M1P7G9 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS17415 ^@ http://purl.uniprot.org/uniprot/M1PEQ6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS02325 ^@ http://purl.uniprot.org/uniprot/M1PKP1 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1167006:UWK_RS18665 ^@ http://purl.uniprot.org/uniprot/M1NIE5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS09020 ^@ http://purl.uniprot.org/uniprot/M1PPN7 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS04635 ^@ http://purl.uniprot.org/uniprot/M1PCP5 ^@ Similarity ^@ Belongs to the DNA photolyase class-2 family. http://togogenome.org/gene/1167006:UWK_RS03990 ^@ http://purl.uniprot.org/uniprot/M1PLM5 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS00540 ^@ http://purl.uniprot.org/uniprot/M1NZJ7 ^@ Similarity ^@ Belongs to the radical SAM superfamily. KamA family. http://togogenome.org/gene/1167006:UWK_RS04335 ^@ http://purl.uniprot.org/uniprot/M1NCE3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS13950 ^@ http://purl.uniprot.org/uniprot/M1P788 ^@ Function|||Similarity ^@ Belongs to the NadD family.|||Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). http://togogenome.org/gene/1167006:UWK_RS07855 ^@ http://purl.uniprot.org/uniprot/M1PEJ1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1167006:UWK_RS11980 ^@ http://purl.uniprot.org/uniprot/M1P676 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1167006:UWK_RS00905 ^@ http://purl.uniprot.org/uniprot/M1PAD5 ^@ Function|||Similarity ^@ Belongs to the NadC/ModD family.|||Involved in the catabolism of quinolinic acid (QA). http://togogenome.org/gene/1167006:UWK_RS11910 ^@ http://purl.uniprot.org/uniprot/M1NH50 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1167006:UWK_RS10215 ^@ http://purl.uniprot.org/uniprot/M1P538 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS01565 ^@ http://purl.uniprot.org/uniprot/M1P5C2 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1167006:UWK_RS08470 ^@ http://purl.uniprot.org/uniprot/M1P9C4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1167006:UWK_RS16065 ^@ http://purl.uniprot.org/uniprot/M1PJN1 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1167006:UWK_RS06715 ^@ http://purl.uniprot.org/uniprot/M1P8C0 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1167006:UWK_RS13940 ^@ http://purl.uniprot.org/uniprot/M1PSN4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS03445 ^@ http://purl.uniprot.org/uniprot/M1NBS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1167006:UWK_RS01695 ^@ http://purl.uniprot.org/uniprot/M1P084 ^@ Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the NifH/BchL/ChlL family.|||Binds 1 [4Fe-4S] cluster per dimer.|||Homodimer.|||The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components: the iron protein and the molybdenum-iron protein.|||The reversible ADP-ribosylation of Arg inactivates the nitrogenase reductase and regulates nitrogenase activity.|||The reversible ADP-ribosylation of Arg-97 inactivates the nitrogenase reductase and regulates nitrogenase activity. http://togogenome.org/gene/1167006:UWK_RS07165 ^@ http://purl.uniprot.org/uniprot/M1PE87 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscL family.|||Cell inner membrane|||Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.|||Homopentamer.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01190 ^@ http://purl.uniprot.org/uniprot/M1PAK1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit.|||Heterotetramer of 2 PyrK and 2 PyrD type B subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). http://togogenome.org/gene/1167006:UWK_RS14210 ^@ http://purl.uniprot.org/uniprot/M1PCR1 ^@ Similarity ^@ Belongs to the MipA/OmpV family. http://togogenome.org/gene/1167006:UWK_RS15065 ^@ http://purl.uniprot.org/uniprot/M1PJ16 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS10200 ^@ http://purl.uniprot.org/uniprot/M1PFZ7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1167006:UWK_RS12855 ^@ http://purl.uniprot.org/uniprot/M1PHQ3 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1167006:UWK_RS11475 ^@ http://purl.uniprot.org/uniprot/M1PGT9 ^@ Similarity ^@ Belongs to the RNA polymerase subunit omega family. http://togogenome.org/gene/1167006:UWK_RS10890 ^@ http://purl.uniprot.org/uniprot/M1PAP9 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1167006:UWK_RS11615 ^@ http://purl.uniprot.org/uniprot/M1NGY2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1167006:UWK_RS17365 ^@ http://purl.uniprot.org/uniprot/M1PEP8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1167006:UWK_RS16235 ^@ http://purl.uniprot.org/uniprot/M1NJP3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily.|||Homodimer.|||Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate. http://togogenome.org/gene/1167006:UWK_RS10115 ^@ http://purl.uniprot.org/uniprot/M1P521 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. http://togogenome.org/gene/1167006:UWK_RS10860 ^@ http://purl.uniprot.org/uniprot/M1PQP5 ^@ Cofactor ^@ Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1167006:UWK_RS10660 ^@ http://purl.uniprot.org/uniprot/M1PQK7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1167006:UWK_RS05940 ^@ http://purl.uniprot.org/uniprot/M1PDE0 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS14420 ^@ http://purl.uniprot.org/uniprot/M1PCV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04125 ^@ http://purl.uniprot.org/uniprot/M1PCC1 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS17945 ^@ http://purl.uniprot.org/uniprot/M1PEZ9 ^@ Similarity ^@ Belongs to the site-specific recombinase resolvase family. http://togogenome.org/gene/1167006:UWK_RS11490 ^@ http://purl.uniprot.org/uniprot/M1P5T8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DksA family.|||Cytoplasm|||Interacts directly with the RNA polymerase.|||Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. http://togogenome.org/gene/1167006:UWK_RS06040 ^@ http://purl.uniprot.org/uniprot/M1PDG8 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1167006:UWK_RS02050 ^@ http://purl.uniprot.org/uniprot/M1P5Q1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.|||Cell inner membrane http://togogenome.org/gene/1167006:UWK_RS10070 ^@ http://purl.uniprot.org/uniprot/M1NFY9 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1167006:UWK_RS01730 ^@ http://purl.uniprot.org/uniprot/M1PAX9 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1167006:UWK_RS15145 ^@ http://purl.uniprot.org/uniprot/M1PJ30 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS06825 ^@ http://purl.uniprot.org/uniprot/M1P394 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1167006:UWK_RS16100 ^@ http://purl.uniprot.org/uniprot/M1PDV7 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1167006:UWK_RS15445 ^@ http://purl.uniprot.org/uniprot/M1PTH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliS family.|||cytosol http://togogenome.org/gene/1167006:UWK_RS15250 ^@ http://purl.uniprot.org/uniprot/M1PDC8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane|||The M ring may be actively involved in energy transduction. http://togogenome.org/gene/1167006:UWK_RS17650 ^@ http://purl.uniprot.org/uniprot/M1P9E7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 3 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1167006:UWK_RS03140 ^@ http://purl.uniprot.org/uniprot/M1PBQ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08370 ^@ http://purl.uniprot.org/uniprot/M1P9A0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS11550 ^@ http://purl.uniprot.org/uniprot/M1PGV7 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1167006:UWK_RS12875 ^@ http://purl.uniprot.org/uniprot/M1NHQ9 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1167006:UWK_RS02485 ^@ http://purl.uniprot.org/uniprot/M1P0P0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.|||Homotetramer.|||Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP. http://togogenome.org/gene/1167006:UWK_RS01770 ^@ http://purl.uniprot.org/uniprot/M1P0A2 ^@ Similarity ^@ Belongs to the NifD/NifK/NifE/NifN family. http://togogenome.org/gene/1167006:UWK_RS06635 ^@ http://purl.uniprot.org/uniprot/M1PDW2 ^@ Similarity ^@ Belongs to the alpha-acetolactate decarboxylase family. http://togogenome.org/gene/1167006:UWK_RS14775 ^@ http://purl.uniprot.org/uniprot/M1P7R9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS17325 ^@ http://purl.uniprot.org/uniprot/M1NKA7 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1167006:UWK_RS02565 ^@ http://purl.uniprot.org/uniprot/M1PBF4 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS11885 ^@ http://purl.uniprot.org/uniprot/M1NH44 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00790 ^@ http://purl.uniprot.org/uniprot/M1NZN4 ^@ Cofactor ^@ Binds 2 Mg(2+) ions per monomer. http://togogenome.org/gene/1167006:UWK_RS04000 ^@ http://purl.uniprot.org/uniprot/M1P1I3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1167006:UWK_RS08665 ^@ http://purl.uniprot.org/uniprot/M1PPE7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1167006:UWK_RS16425 ^@ http://purl.uniprot.org/uniprot/M1P8M8 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1167006:UWK_RS15730 ^@ http://purl.uniprot.org/uniprot/M1PDM9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1167006:UWK_RS16840 ^@ http://purl.uniprot.org/uniprot/M1P8X2 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS06515 ^@ http://purl.uniprot.org/uniprot/M1PDS9 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS14920 ^@ http://purl.uniprot.org/uniprot/M1PD56 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1167006:UWK_RS12730 ^@ http://purl.uniprot.org/uniprot/M1PHM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS12565 ^@ http://purl.uniprot.org/uniprot/M1PBR7 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS10435 ^@ http://purl.uniprot.org/uniprot/M1P574 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1167006:UWK_RS11405 ^@ http://purl.uniprot.org/uniprot/M1PR19 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.|||Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.|||Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.|||Heterodimer of a large and a small subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Periplasm|||Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven. http://togogenome.org/gene/1167006:UWK_RS10015 ^@ http://purl.uniprot.org/uniprot/M1P510 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1167006:UWK_RS11765 ^@ http://purl.uniprot.org/uniprot/M1NH16 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14270 ^@ http://purl.uniprot.org/uniprot/M1NIL3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS05220 ^@ http://purl.uniprot.org/uniprot/M1PCY5 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1167006:UWK_RS18085 ^@ http://purl.uniprot.org/uniprot/M1PKJ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RTX toxin acyltransferase family.|||Cytoplasm|||Involved in fatty acylation of protoxin at internal lysine residues, thereby converting it to the active toxin. http://togogenome.org/gene/1167006:UWK_RS14185 ^@ http://purl.uniprot.org/uniprot/M1PCQ6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS10290 ^@ http://purl.uniprot.org/uniprot/M1PAD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1167006:UWK_RS01290 ^@ http://purl.uniprot.org/uniprot/M1PAM5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS15075 ^@ http://purl.uniprot.org/uniprot/M1PD90 ^@ Subunit ^@ Heterodimer of a large and a small subunit. http://togogenome.org/gene/1167006:UWK_RS14415 ^@ http://purl.uniprot.org/uniprot/M1PSZ5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS11180 ^@ http://purl.uniprot.org/uniprot/M1PGL7 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1167006:UWK_RS02305 ^@ http://purl.uniprot.org/uniprot/M1P5T9 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIS family. GmhA subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.|||Cytoplasm|||Homotetramer.|||The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate. http://togogenome.org/gene/1167006:UWK_RS08805 ^@ http://purl.uniprot.org/uniprot/M1NF75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS10355 ^@ http://purl.uniprot.org/uniprot/M1PQF2 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS17230 ^@ http://purl.uniprot.org/uniprot/M1PKG2 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/1167006:UWK_RS08340 ^@ http://purl.uniprot.org/uniprot/M1PP85 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1167006:UWK_RS17295 ^@ http://purl.uniprot.org/uniprot/M1P989 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS00115 ^@ http://purl.uniprot.org/uniprot/M1PJD9 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1167006:UWK_RS07285 ^@ http://purl.uniprot.org/uniprot/M1PEA5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS18285 ^@ http://purl.uniprot.org/uniprot/M1P2L0 ^@ Similarity ^@ Belongs to the hemerythrin family.|||Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS08105 ^@ http://purl.uniprot.org/uniprot/M1NEQ1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1167006:UWK_RS00360 ^@ http://purl.uniprot.org/uniprot/M1N9X7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Catalyzes the attachment of tryptophan to tRNA(Trp).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS08795 ^@ http://purl.uniprot.org/uniprot/M1P9J3 ^@ Similarity ^@ Belongs to the mannose-6-phosphate isomerase type 2 family. http://togogenome.org/gene/1167006:UWK_RS17610 ^@ http://purl.uniprot.org/uniprot/M1PUR2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the imidazoleglycerol-phosphate dehydratase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS08110 ^@ http://purl.uniprot.org/uniprot/M1PEP7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS13930 ^@ http://purl.uniprot.org/uniprot/M1NIE0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1167006:UWK_RS16715 ^@ http://purl.uniprot.org/uniprot/M1P8U3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1167006:UWK_RS11585 ^@ http://purl.uniprot.org/uniprot/M1P5W9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS16640 ^@ http://purl.uniprot.org/uniprot/M1P8S3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1167006:UWK_RS13175 ^@ http://purl.uniprot.org/uniprot/M1PHW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1167006:UWK_RS07525 ^@ http://purl.uniprot.org/uniprot/M1P3M9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS16240 ^@ http://purl.uniprot.org/uniprot/M1PJR7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1167006:UWK_RS01845 ^@ http://purl.uniprot.org/uniprot/M1P0C2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10160 ^@ http://purl.uniprot.org/uniprot/M1PAB8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1167006:UWK_RS16135 ^@ http://purl.uniprot.org/uniprot/M1PJP7 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1167006:UWK_RS01175 ^@ http://purl.uniprot.org/uniprot/M1P527 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. http://togogenome.org/gene/1167006:UWK_RS15510 ^@ http://purl.uniprot.org/uniprot/M1NJB7 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1167006:UWK_RS04390 ^@ http://purl.uniprot.org/uniprot/M1PLX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03940 ^@ http://purl.uniprot.org/uniprot/M1P6L9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS11720 ^@ http://purl.uniprot.org/uniprot/M1PGZ8 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1167006:UWK_RS00445 ^@ http://purl.uniprot.org/uniprot/M1PA43 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1167006:UWK_RS00330 ^@ http://purl.uniprot.org/uniprot/M1NZG1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1167006:UWK_RS04660 ^@ http://purl.uniprot.org/uniprot/M1PM48 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1167006:UWK_RS15320 ^@ http://purl.uniprot.org/uniprot/M1PTF5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliO/MopB family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS15810 ^@ http://purl.uniprot.org/uniprot/M1P8A0 ^@ Similarity ^@ Belongs to the BPG-independent phosphoglycerate mutase family. http://togogenome.org/gene/1167006:UWK_RS05235 ^@ http://purl.uniprot.org/uniprot/M1P2A9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TrkH potassium transport family.|||Cell inner membrane|||Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.|||Membrane http://togogenome.org/gene/1167006:UWK_RS14900 ^@ http://purl.uniprot.org/uniprot/M1P7U1 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1167006:UWK_RS16590 ^@ http://purl.uniprot.org/uniprot/M1NJV5 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS01925 ^@ http://purl.uniprot.org/uniprot/M1NAX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS08545 ^@ http://purl.uniprot.org/uniprot/M1P9D9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1167006:UWK_RS01705 ^@ http://purl.uniprot.org/uniprot/M1PAX1 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1167006:UWK_RS18340 ^@ http://purl.uniprot.org/uniprot/M1NE36 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS08080 ^@ http://purl.uniprot.org/uniprot/M1NEP7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M48B family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS14745 ^@ http://purl.uniprot.org/uniprot/M1PD22 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1167006:UWK_RS05325 ^@ http://purl.uniprot.org/uniprot/M1P7G4 ^@ Similarity ^@ Belongs to the autoinducer synthase family. http://togogenome.org/gene/1167006:UWK_RS01615 ^@ http://purl.uniprot.org/uniprot/M1P5D7 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS07345 ^@ http://purl.uniprot.org/uniprot/M1P8R7 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1167006:UWK_RS00365 ^@ http://purl.uniprot.org/uniprot/M1PA29 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1167006:UWK_RS09835 ^@ http://purl.uniprot.org/uniprot/M1PA72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS17665 ^@ http://purl.uniprot.org/uniprot/M1PUS2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1167006:UWK_RS12345 ^@ http://purl.uniprot.org/uniprot/M1PBM7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS15390 ^@ http://purl.uniprot.org/uniprot/M1PJ79 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.|||Bacterial flagellum basal body|||Belongs to the FlgI family.|||Periplasm|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. http://togogenome.org/gene/1167006:UWK_RS13550 ^@ http://purl.uniprot.org/uniprot/M1P718 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1167006:UWK_RS06180 ^@ http://purl.uniprot.org/uniprot/M1PDJ9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/1167006:UWK_RS13100 ^@ http://purl.uniprot.org/uniprot/M1PHV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS09735 ^@ http://purl.uniprot.org/uniprot/M1NFU3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS17245 ^@ http://purl.uniprot.org/uniprot/M1P980 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0014 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS02585 ^@ http://purl.uniprot.org/uniprot/M1NBB6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Homohexamer.|||In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.|||In the N-terminal section; belongs to the CobB/CobQ family.|||Involved in acetate metabolism.|||The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site. http://togogenome.org/gene/1167006:UWK_RS09615 ^@ http://purl.uniprot.org/uniprot/M1PFQ5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 3 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16420 ^@ http://purl.uniprot.org/uniprot/M1PE28 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS12770 ^@ http://purl.uniprot.org/uniprot/M1P6M9 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS10990 ^@ http://purl.uniprot.org/uniprot/M1PAR9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1167006:UWK_RS14410 ^@ http://purl.uniprot.org/uniprot/M1PIL8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS10755 ^@ http://purl.uniprot.org/uniprot/M1NGC5 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1167006:UWK_RS18455 ^@ http://purl.uniprot.org/uniprot/M1NFG8 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1167006:UWK_RS12255 ^@ http://purl.uniprot.org/uniprot/M1NHD2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05375 ^@ http://purl.uniprot.org/uniprot/M1P7H5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS00910 ^@ http://purl.uniprot.org/uniprot/M1PJT0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1167006:UWK_RS17685 ^@ http://purl.uniprot.org/uniprot/M1PKP5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1167006:UWK_RS17630 ^@ http://purl.uniprot.org/uniprot/M1NKF4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS17300 ^@ http://purl.uniprot.org/uniprot/M1NKA3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS07370 ^@ http://purl.uniprot.org/uniprot/M1P8S1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1167006:UWK_RS03440 ^@ http://purl.uniprot.org/uniprot/M1P150 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS17085 ^@ http://purl.uniprot.org/uniprot/M1PEG5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS05805 ^@ http://purl.uniprot.org/uniprot/M1P7Q4 ^@ Function|||Similarity ^@ Belongs to the HypA/HybF family.|||Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. http://togogenome.org/gene/1167006:UWK_RS06755 ^@ http://purl.uniprot.org/uniprot/M1NDY4 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 8 (cellulase D) family. http://togogenome.org/gene/1167006:UWK_RS10185 ^@ http://purl.uniprot.org/uniprot/M1PAC1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS11695 ^@ http://purl.uniprot.org/uniprot/M1PGZ2 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1167006:UWK_RS05770 ^@ http://purl.uniprot.org/uniprot/M1PD94 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1167006:UWK_RS00935 ^@ http://purl.uniprot.org/uniprot/M1PJT3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.|||Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS02160 ^@ http://purl.uniprot.org/uniprot/M1P0J4 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1167006:UWK_RS17355 ^@ http://purl.uniprot.org/uniprot/M1PKI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16210 ^@ http://purl.uniprot.org/uniprot/M1NJP0 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1167006:UWK_RS04200 ^@ http://purl.uniprot.org/uniprot/M1PLS3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS11380 ^@ http://purl.uniprot.org/uniprot/M1PR13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS10370 ^@ http://purl.uniprot.org/uniprot/M1NG44 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1167006:UWK_RS01170 ^@ http://purl.uniprot.org/uniprot/M1PJX6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the shikimate dehydrogenase family.|||Homodimer.|||Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS09275 ^@ http://purl.uniprot.org/uniprot/M1P9V4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14670 ^@ http://purl.uniprot.org/uniprot/M1PD15 ^@ Function|||Similarity ^@ Belongs to the CobU/CobP family.|||Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. http://togogenome.org/gene/1167006:UWK_RS16895 ^@ http://purl.uniprot.org/uniprot/M1NK09 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS08065 ^@ http://purl.uniprot.org/uniprot/M1PP30 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03185 ^@ http://purl.uniprot.org/uniprot/M1NBM4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1167006:UWK_RS00460 ^@ http://purl.uniprot.org/uniprot/M1NZI4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS00125 ^@ http://purl.uniprot.org/uniprot/M1NZD7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS15815 ^@ http://purl.uniprot.org/uniprot/M1NJG8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS10050 ^@ http://purl.uniprot.org/uniprot/M1PFX0 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1167006:UWK_RS12365 ^@ http://purl.uniprot.org/uniprot/M1PBN3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1167006:UWK_RS10760 ^@ http://purl.uniprot.org/uniprot/M1PGC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS04675 ^@ http://purl.uniprot.org/uniprot/M1PCQ2 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS06845 ^@ http://purl.uniprot.org/uniprot/M1P8F3 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS13750 ^@ http://purl.uniprot.org/uniprot/M1PSI9 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1167006:UWK_RS12860 ^@ http://purl.uniprot.org/uniprot/M1PRZ7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS08050 ^@ http://purl.uniprot.org/uniprot/M1P3W6 ^@ Similarity ^@ Belongs to the YggT family. http://togogenome.org/gene/1167006:UWK_RS10315 ^@ http://purl.uniprot.org/uniprot/M1P555 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1167006:UWK_RS13965 ^@ http://purl.uniprot.org/uniprot/M1PSP1 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS16490 ^@ http://purl.uniprot.org/uniprot/M1PU32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01605 ^@ http://purl.uniprot.org/uniprot/M1PAU6 ^@ Similarity ^@ Belongs to the glucose-6-phosphate 1-epimerase family. http://togogenome.org/gene/1167006:UWK_RS14550 ^@ http://purl.uniprot.org/uniprot/M1PT24 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1167006:UWK_RS08800 ^@ http://purl.uniprot.org/uniprot/M1P4A9 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1167006:UWK_RS18505 ^@ http://purl.uniprot.org/uniprot/M1PQ32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS11040 ^@ http://purl.uniprot.org/uniprot/M1PAS9 ^@ Function ^@ The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. http://togogenome.org/gene/1167006:UWK_RS07945 ^@ http://purl.uniprot.org/uniprot/M1P917 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS04595 ^@ http://purl.uniprot.org/uniprot/M1P735 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1167006:UWK_RS15090 ^@ http://purl.uniprot.org/uniprot/M1PJ21 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1167006:UWK_RS04970 ^@ http://purl.uniprot.org/uniprot/M1PCU5 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1167006:UWK_RS04990 ^@ http://purl.uniprot.org/uniprot/M1NCU8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS05045 ^@ http://purl.uniprot.org/uniprot/M1NCV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08855 ^@ http://purl.uniprot.org/uniprot/M1NF88 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS07005 ^@ http://purl.uniprot.org/uniprot/M1PNG8 ^@ Similarity ^@ Belongs to the AOR/FOR family. http://togogenome.org/gene/1167006:UWK_RS16260 ^@ http://purl.uniprot.org/uniprot/M1NJP8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09920 ^@ http://purl.uniprot.org/uniprot/M1NFX0 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1167006:UWK_RS04780 ^@ http://purl.uniprot.org/uniprot/M1P766 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1167006:UWK_RS00130 ^@ http://purl.uniprot.org/uniprot/M1N9T0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1167006:UWK_RS12980 ^@ http://purl.uniprot.org/uniprot/M1PS18 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1167006:UWK_RS05775 ^@ http://purl.uniprot.org/uniprot/M1PMQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HupC/HyaC/HydC family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS14065 ^@ http://purl.uniprot.org/uniprot/M1PCM7 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1167006:UWK_RS09195 ^@ http://purl.uniprot.org/uniprot/M1PPT7 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1167006:UWK_RS06450 ^@ http://purl.uniprot.org/uniprot/M1P854 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1167006:UWK_RS09525 ^@ http://purl.uniprot.org/uniprot/M1P4S3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1167006:UWK_RS05555 ^@ http://purl.uniprot.org/uniprot/M1PMK6 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1167006:UWK_RS08755 ^@ http://purl.uniprot.org/uniprot/M1NF62 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS03945 ^@ http://purl.uniprot.org/uniprot/M1P1H1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16830 ^@ http://purl.uniprot.org/uniprot/M1PK43 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08295 ^@ http://purl.uniprot.org/uniprot/M1P982 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1167006:UWK_RS00465 ^@ http://purl.uniprot.org/uniprot/M1N9Z8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS20000 ^@ http://purl.uniprot.org/uniprot/M1PDG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1167006:UWK_RS10800 ^@ http://purl.uniprot.org/uniprot/M1P5E4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00120 ^@ http://purl.uniprot.org/uniprot/M1P4I9 ^@ Function|||Similarity ^@ Belongs to the PNP/MTAP phosphorylase family.|||The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. http://togogenome.org/gene/1167006:UWK_RS12340 ^@ http://purl.uniprot.org/uniprot/M1PRQ8 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS00325 ^@ http://purl.uniprot.org/uniprot/M1P4M6 ^@ Function|||Similarity ^@ Belongs to the DHPS family.|||Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. http://togogenome.org/gene/1167006:UWK_RS04845 ^@ http://purl.uniprot.org/uniprot/M1NCS0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.|||Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS04175 ^@ http://purl.uniprot.org/uniprot/M1PLR6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS00160 ^@ http://purl.uniprot.org/uniprot/M1P9Z8 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1167006:UWK_RS10535 ^@ http://purl.uniprot.org/uniprot/M1PQI3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS16275 ^@ http://purl.uniprot.org/uniprot/M1PDZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the EamA transporter family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS04015 ^@ http://purl.uniprot.org/uniprot/M1PLN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS02545 ^@ http://purl.uniprot.org/uniprot/M1PKT2 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS06445 ^@ http://purl.uniprot.org/uniprot/M1PN36 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1167006:UWK_RS09095 ^@ http://purl.uniprot.org/uniprot/M1PPQ9 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/1167006:UWK_RS10255 ^@ http://purl.uniprot.org/uniprot/M1PG05 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1167006:UWK_RS00620 ^@ http://purl.uniprot.org/uniprot/M1NA27 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1167006:UWK_RS05080 ^@ http://purl.uniprot.org/uniprot/M1PMC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS17620 ^@ http://purl.uniprot.org/uniprot/M1PEU3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL13 family.|||Part of the 50S ribosomal subunit.|||This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. http://togogenome.org/gene/1167006:UWK_RS07920 ^@ http://purl.uniprot.org/uniprot/M1PP00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 1 family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS00915 ^@ http://purl.uniprot.org/uniprot/M1P4X9 ^@ Similarity ^@ Belongs to the dGTPase family. Type 2 subfamily. http://togogenome.org/gene/1167006:UWK_RS17395 ^@ http://purl.uniprot.org/uniprot/M1P9A5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1167006:UWK_RS06510 ^@ http://purl.uniprot.org/uniprot/M1NDR2 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. http://togogenome.org/gene/1167006:UWK_RS04070 ^@ http://purl.uniprot.org/uniprot/M1P6P9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1167006:UWK_RS00440 ^@ http://purl.uniprot.org/uniprot/M1N9Z4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1167006:UWK_RS10170 ^@ http://purl.uniprot.org/uniprot/M1PAB0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1167006:UWK_RS14290 ^@ http://purl.uniprot.org/uniprot/M1P7H0 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1167006:UWK_RS17450 ^@ http://purl.uniprot.org/uniprot/M1PKK2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16405 ^@ http://purl.uniprot.org/uniprot/M1NJS6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09840 ^@ http://purl.uniprot.org/uniprot/M1P4Y6 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1167006:UWK_RS11665 ^@ http://purl.uniprot.org/uniprot/M1P5Z3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10210 ^@ http://purl.uniprot.org/uniprot/M1PAC6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1167006:UWK_RS08100 ^@ http://purl.uniprot.org/uniprot/M1P3X7 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1167006:UWK_RS04280 ^@ http://purl.uniprot.org/uniprot/M1P1Q3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1167006:UWK_RS01155 ^@ http://purl.uniprot.org/uniprot/M1NZV9 ^@ Similarity ^@ Belongs to the peptidase C40 family. http://togogenome.org/gene/1167006:UWK_RS06745 ^@ http://purl.uniprot.org/uniprot/M1P8C7 ^@ Function|||Subcellular Location Annotation ^@ Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.|||Cell inner membrane http://togogenome.org/gene/1167006:UWK_RS17625 ^@ http://purl.uniprot.org/uniprot/M1P9E3 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1167006:UWK_RS07405 ^@ http://purl.uniprot.org/uniprot/M1PEC1 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1167006:UWK_RS10565 ^@ http://purl.uniprot.org/uniprot/M1PAI9 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1167006:UWK_RS13905 ^@ http://purl.uniprot.org/uniprot/M1NID4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1167006:UWK_RS14890 ^@ http://purl.uniprot.org/uniprot/M1PT87 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1167006:UWK_RS01005 ^@ http://purl.uniprot.org/uniprot/M1PAF7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS13210 ^@ http://purl.uniprot.org/uniprot/M1PC47 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1167006:UWK_RS04905 ^@ http://purl.uniprot.org/uniprot/M1PM91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase epsilon chain family.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1167006:UWK_RS06320 ^@ http://purl.uniprot.org/uniprot/M1P824 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05035 ^@ http://purl.uniprot.org/uniprot/M1P7A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS10555 ^@ http://purl.uniprot.org/uniprot/M1PG75 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1167006:UWK_RS01030 ^@ http://purl.uniprot.org/uniprot/M1PAG4 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1167006:UWK_RS14280 ^@ http://purl.uniprot.org/uniprot/M1PSW8 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1167006:UWK_RS10940 ^@ http://purl.uniprot.org/uniprot/M1PAQ8 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS16905 ^@ http://purl.uniprot.org/uniprot/M1PUC4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1167006:UWK_RS18260 ^@ http://purl.uniprot.org/uniprot/M1PMH6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1167006:UWK_RS08090 ^@ http://purl.uniprot.org/uniprot/M1PP35 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1167006:UWK_RS09470 ^@ http://purl.uniprot.org/uniprot/M1PPZ6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1167006:UWK_RS09560 ^@ http://purl.uniprot.org/uniprot/M1NFR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1167006:UWK_RS07600 ^@ http://purl.uniprot.org/uniprot/M1P3P3 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1167006:UWK_RS01540 ^@ http://purl.uniprot.org/uniprot/M1P5B6 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1167006:UWK_RS08720 ^@ http://purl.uniprot.org/uniprot/M1P9H7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS04010 ^@ http://purl.uniprot.org/uniprot/M1PC98 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1167006:UWK_RS15035 ^@ http://purl.uniprot.org/uniprot/M1NJ41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS13945 ^@ http://purl.uniprot.org/uniprot/M1PCK2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS05400 ^@ http://purl.uniprot.org/uniprot/M1P7I0 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1167006:UWK_RS07140 ^@ http://purl.uniprot.org/uniprot/M1PE83 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1167006:UWK_RS06855 ^@ http://purl.uniprot.org/uniprot/M1NE11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1167006:UWK_RS06920 ^@ http://purl.uniprot.org/uniprot/M1PE26 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08270 ^@ http://purl.uniprot.org/uniprot/M1P975 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS17635 ^@ http://purl.uniprot.org/uniprot/M1PKN5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS14655 ^@ http://purl.uniprot.org/uniprot/M1NIX6 ^@ Function|||Similarity ^@ Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.|||Decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin. http://togogenome.org/gene/1167006:UWK_RS13155 ^@ http://purl.uniprot.org/uniprot/M1PS52 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1167006:UWK_RS05650 ^@ http://purl.uniprot.org/uniprot/M1PMM5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS18120 ^@ http://purl.uniprot.org/uniprot/M1PL22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS05140 ^@ http://purl.uniprot.org/uniprot/M1P291 ^@ Function|||Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.|||Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate. http://togogenome.org/gene/1167006:UWK_RS08335 ^@ http://purl.uniprot.org/uniprot/M1PEU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05840 ^@ http://purl.uniprot.org/uniprot/M1PDB3 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1167006:UWK_RS08260 ^@ http://purl.uniprot.org/uniprot/M1PET1 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS01505 ^@ http://purl.uniprot.org/uniprot/M1PK46 ^@ Similarity ^@ Belongs to the HisA/HisF family. http://togogenome.org/gene/1167006:UWK_RS13895 ^@ http://purl.uniprot.org/uniprot/M1PCJ0 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1167006:UWK_RS11985 ^@ http://purl.uniprot.org/uniprot/M1NH65 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1167006:UWK_RS13065 ^@ http://purl.uniprot.org/uniprot/M1P6T2 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1167006:UWK_RS11580 ^@ http://purl.uniprot.org/uniprot/M1PB49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS06295 ^@ http://purl.uniprot.org/uniprot/M1P818 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1167006:UWK_RS13810 ^@ http://purl.uniprot.org/uniprot/M1PCH4 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1167006:UWK_RS07725 ^@ http://purl.uniprot.org/uniprot/M1NEI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS13740 ^@ http://purl.uniprot.org/uniprot/M1NI99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1167006:UWK_RS05820 ^@ http://purl.uniprot.org/uniprot/M1PMR3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. http://togogenome.org/gene/1167006:UWK_RS01595 ^@ http://purl.uniprot.org/uniprot/M1P059 ^@ Similarity ^@ Belongs to the IlvD/Edd family. http://togogenome.org/gene/1167006:UWK_RS10415 ^@ http://purl.uniprot.org/uniprot/M1NG54 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05380 ^@ http://purl.uniprot.org/uniprot/M1P2D8 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS14070 ^@ http://purl.uniprot.org/uniprot/M1P7B7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS12725 ^@ http://purl.uniprot.org/uniprot/M1NHM8 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1167006:UWK_RS12715 ^@ http://purl.uniprot.org/uniprot/M1PBU5 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS12740 ^@ http://purl.uniprot.org/uniprot/M1PBU9 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1167006:UWK_RS14320 ^@ http://purl.uniprot.org/uniprot/M1P7H7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1167006:UWK_RS09640 ^@ http://purl.uniprot.org/uniprot/M1PQ44 ^@ Function|||Similarity ^@ Belongs to the band 7/mec-2 family. HflC subfamily.|||HflC and HflK could regulate a protease. http://togogenome.org/gene/1167006:UWK_RS10585 ^@ http://purl.uniprot.org/uniprot/M1PQJ4 ^@ Similarity ^@ Belongs to the RemA family. http://togogenome.org/gene/1167006:UWK_RS05180 ^@ http://purl.uniprot.org/uniprot/M1P2A0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS08255 ^@ http://purl.uniprot.org/uniprot/M1NET5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1167006:UWK_RS16525 ^@ http://purl.uniprot.org/uniprot/M1P8P7 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS08740 ^@ http://purl.uniprot.org/uniprot/M1PPG2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1167006:UWK_RS10335 ^@ http://purl.uniprot.org/uniprot/M1PAE7 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS14540 ^@ http://purl.uniprot.org/uniprot/M1NIS7 ^@ Function|||Similarity ^@ Belongs to the RecD family. RecD-like subfamily.|||DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity. http://togogenome.org/gene/1167006:UWK_RS02945 ^@ http://purl.uniprot.org/uniprot/M1PBL6 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1167006:UWK_RS11470 ^@ http://purl.uniprot.org/uniprot/M1NGU6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1167006:UWK_RS15020 ^@ http://purl.uniprot.org/uniprot/M1PTA5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1167006:UWK_RS08520 ^@ http://purl.uniprot.org/uniprot/M1P9D4 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1167006:UWK_RS04800 ^@ http://purl.uniprot.org/uniprot/M1PM75 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1167006:UWK_RS16690 ^@ http://purl.uniprot.org/uniprot/M1P8T5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1167006:UWK_RS10235 ^@ http://purl.uniprot.org/uniprot/M1PAC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS07080 ^@ http://purl.uniprot.org/uniprot/M1P3G0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter small permease family.|||Cell inner membrane|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1167006:UWK_RS14600 ^@ http://purl.uniprot.org/uniprot/M1PT40 ^@ Function|||Similarity ^@ Belongs to the PINc/VapC protein family.|||Toxic component of a toxin-antitoxin (TA) system. An RNase. http://togogenome.org/gene/1167006:UWK_RS15775 ^@ http://purl.uniprot.org/uniprot/M1PTM8 ^@ Similarity ^@ Belongs to the UPF0301 (AlgH) family. http://togogenome.org/gene/1167006:UWK_RS06850 ^@ http://purl.uniprot.org/uniprot/M1P399 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1167006:UWK_RS08915 ^@ http://purl.uniprot.org/uniprot/M1PPL0 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1167006:UWK_RS03970 ^@ http://purl.uniprot.org/uniprot/M1P6M6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01995 ^@ http://purl.uniprot.org/uniprot/M1P0G8 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1167006:UWK_RS01185 ^@ http://purl.uniprot.org/uniprot/M1NAD5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS00400 ^@ http://purl.uniprot.org/uniprot/M1PJJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09050 ^@ http://purl.uniprot.org/uniprot/M1P9P9 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Belongs to the cysteine synthase/cystathionine beta-synthase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS08140 ^@ http://purl.uniprot.org/uniprot/M1PP46 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1167006:UWK_RS09880 ^@ http://purl.uniprot.org/uniprot/M1PQ80 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS09565 ^@ http://purl.uniprot.org/uniprot/M1PFP7 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1167006:UWK_RS02280 ^@ http://purl.uniprot.org/uniprot/M1P5T5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DsrC/TusE family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS19610 ^@ http://purl.uniprot.org/uniprot/M1PH51 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1167006:UWK_RS15255 ^@ http://purl.uniprot.org/uniprot/M1P803 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS16570 ^@ http://purl.uniprot.org/uniprot/M1PJY1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1167006:UWK_RS05930 ^@ http://purl.uniprot.org/uniprot/M1P2P3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS14040 ^@ http://purl.uniprot.org/uniprot/M1PCM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15240 ^@ http://purl.uniprot.org/uniprot/M1PJ48 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1167006:UWK_RS06670 ^@ http://purl.uniprot.org/uniprot/M1P8A7 ^@ Similarity ^@ Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. http://togogenome.org/gene/1167006:UWK_RS18010 ^@ http://purl.uniprot.org/uniprot/M1NA73 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS02990 ^@ http://purl.uniprot.org/uniprot/M1NBI8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS15665 ^@ http://purl.uniprot.org/uniprot/M1NJE1 ^@ Similarity ^@ Belongs to the HdrA family. http://togogenome.org/gene/1167006:UWK_RS08980 ^@ http://purl.uniprot.org/uniprot/M1NFB9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12055 ^@ http://purl.uniprot.org/uniprot/M1P696 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS16385 ^@ http://purl.uniprot.org/uniprot/M1PJU7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS03075 ^@ http://purl.uniprot.org/uniprot/M1P667 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PEPCase type 1 family.|||Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS10155 ^@ http://purl.uniprot.org/uniprot/M1PQB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1167006:UWK_RS02805 ^@ http://purl.uniprot.org/uniprot/M1P0T7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01235 ^@ http://purl.uniprot.org/uniprot/M1NAE6 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1167006:UWK_RS05285 ^@ http://purl.uniprot.org/uniprot/M1P2B7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1167006:UWK_RS01460 ^@ http://purl.uniprot.org/uniprot/M1P596 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS12745 ^@ http://purl.uniprot.org/uniprot/M1P6M7 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1167006:UWK_RS06275 ^@ http://purl.uniprot.org/uniprot/M1P2V7 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS04685 ^@ http://purl.uniprot.org/uniprot/M1P752 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12460 ^@ http://purl.uniprot.org/uniprot/M1PRS6 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1167006:UWK_RS12755 ^@ http://purl.uniprot.org/uniprot/M1PHN3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1167006:UWK_RS17475 ^@ http://purl.uniprot.org/uniprot/M1PKK5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.|||CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.|||Homodimer, forms a heterotetramer with a Cas1 homodimer. http://togogenome.org/gene/1167006:UWK_RS07385 ^@ http://purl.uniprot.org/uniprot/M1PNR0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS05185 ^@ http://purl.uniprot.org/uniprot/M1NCY2 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1167006:UWK_RS14815 ^@ http://purl.uniprot.org/uniprot/M1PT76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05465 ^@ http://purl.uniprot.org/uniprot/M1PMJ4 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1167006:UWK_RS14330 ^@ http://purl.uniprot.org/uniprot/M1PIJ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS05860 ^@ http://purl.uniprot.org/uniprot/M1NDA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.|||Belongs to the SrkA/RdoA protein kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS19575 ^@ http://purl.uniprot.org/uniprot/M1P7N9 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1167006:UWK_RS12615 ^@ http://purl.uniprot.org/uniprot/M1PRV0 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS04410 ^@ http://purl.uniprot.org/uniprot/M1PCI3 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1167006:UWK_RS06170 ^@ http://purl.uniprot.org/uniprot/M1P2T8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1167006:UWK_RS10590 ^@ http://purl.uniprot.org/uniprot/M1PAJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1167006:UWK_RS08650 ^@ http://purl.uniprot.org/uniprot/M1P482 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS01610 ^@ http://purl.uniprot.org/uniprot/M1PK67 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1167006:UWK_RS02785 ^@ http://purl.uniprot.org/uniprot/M1NBF0 ^@ Similarity ^@ Belongs to the glycosyltransferase 1 family. http://togogenome.org/gene/1167006:UWK_RS11455 ^@ http://purl.uniprot.org/uniprot/M1PR32 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1167006:UWK_RS12625 ^@ http://purl.uniprot.org/uniprot/M1P6K8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS06250 ^@ http://purl.uniprot.org/uniprot/M1P2V3 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS07530 ^@ http://purl.uniprot.org/uniprot/M1NEE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS09545 ^@ http://purl.uniprot.org/uniprot/M1PA19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS15285 ^@ http://purl.uniprot.org/uniprot/M1NJ81 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1167006:UWK_RS08705 ^@ http://purl.uniprot.org/uniprot/M1NF50 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS09000 ^@ http://purl.uniprot.org/uniprot/M1P9N6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04045 ^@ http://purl.uniprot.org/uniprot/M1P6P2 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1167006:UWK_RS01550 ^@ http://purl.uniprot.org/uniprot/M1NAM4 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1167006:UWK_RS07235 ^@ http://purl.uniprot.org/uniprot/M1PNN3 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS07315 ^@ http://purl.uniprot.org/uniprot/M1PNP7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS02810 ^@ http://purl.uniprot.org/uniprot/M1NBF3 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT. http://togogenome.org/gene/1167006:UWK_RS11480 ^@ http://purl.uniprot.org/uniprot/M1PR38 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1167006:UWK_RS11895 ^@ http://purl.uniprot.org/uniprot/M1PH41 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS06685 ^@ http://purl.uniprot.org/uniprot/M1PDX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS04625 ^@ http://purl.uniprot.org/uniprot/M1P202 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ferredoxin thioredoxin reductase beta subunit family.|||Catalytic subunit of the ferredoxin-thioredoxin reductase (FTR), which catalyzes the two-electron reduction of thioredoxins by the electrons provided by reduced ferredoxin.|||Heterodimer of subunit A (variable subunit) and subunit B (catalytic subunit). Heterodimeric FTR forms a complex with ferredoxin and thioredoxin. http://togogenome.org/gene/1167006:UWK_RS06060 ^@ http://purl.uniprot.org/uniprot/M1NDE6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS11680 ^@ http://purl.uniprot.org/uniprot/M1PB71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS15745 ^@ http://purl.uniprot.org/uniprot/M1PJF5 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1167006:UWK_RS00055 ^@ http://purl.uniprot.org/uniprot/M1PJD0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1167006:UWK_RS16620 ^@ http://purl.uniprot.org/uniprot/M1NJW0 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1167006:UWK_RS01295 ^@ http://purl.uniprot.org/uniprot/M1PK04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16925 ^@ http://purl.uniprot.org/uniprot/M1PK70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1167006:UWK_RS11510 ^@ http://purl.uniprot.org/uniprot/M1PB34 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1167006:UWK_RS10230 ^@ http://purl.uniprot.org/uniprot/M1PQC9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1167006:UWK_RS10055 ^@ http://purl.uniprot.org/uniprot/M1PQA5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/1167006:UWK_RS03415 ^@ http://purl.uniprot.org/uniprot/M1P145 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1167006:UWK_RS10270 ^@ http://purl.uniprot.org/uniprot/M1P547 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS10650 ^@ http://purl.uniprot.org/uniprot/M1NGA3 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1167006:UWK_RS01795 ^@ http://purl.uniprot.org/uniprot/M1P0A8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS15580 ^@ http://purl.uniprot.org/uniprot/M1P861 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1167006:UWK_RS15450 ^@ http://purl.uniprot.org/uniprot/M1PDH1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum|||Belongs to the FliD family.|||Homopentamer.|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.|||Secreted http://togogenome.org/gene/1167006:UWK_RS01950 ^@ http://purl.uniprot.org/uniprot/M1NAY9 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1167006:UWK_RS00200 ^@ http://purl.uniprot.org/uniprot/M1NZE5 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1167006:UWK_RS18060 ^@ http://purl.uniprot.org/uniprot/M1PKD2 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1167006:UWK_RS08555 ^@ http://purl.uniprot.org/uniprot/M1PF01 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1167006:UWK_RS08820 ^@ http://purl.uniprot.org/uniprot/M1PPI1 ^@ Activity Regulation|||Caution|||Domain|||Function|||Similarity ^@ Belongs to the GlnD family.|||Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism.|||Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity. http://togogenome.org/gene/1167006:UWK_RS01645 ^@ http://purl.uniprot.org/uniprot/M1NAQ2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS17575 ^@ http://purl.uniprot.org/uniprot/M1PKM5 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS04835 ^@ http://purl.uniprot.org/uniprot/M1P774 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14245 ^@ http://purl.uniprot.org/uniprot/M1NIK8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS17320 ^@ http://purl.uniprot.org/uniprot/M1P993 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1167006:UWK_RS13460 ^@ http://purl.uniprot.org/uniprot/M1PSB8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS10830 ^@ http://purl.uniprot.org/uniprot/M1NGD9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the R-transferase family. Bpt subfamily.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. http://togogenome.org/gene/1167006:UWK_RS11870 ^@ http://purl.uniprot.org/uniprot/M1PRE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1167006:UWK_RS12965 ^@ http://purl.uniprot.org/uniprot/M1P6R5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05505 ^@ http://purl.uniprot.org/uniprot/M1P2F9 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/1167006:UWK_RS12350 ^@ http://purl.uniprot.org/uniprot/M1NHE9 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1167006:UWK_RS04680 ^@ http://purl.uniprot.org/uniprot/M1PM52 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the transcriptional regulatory CopG/NikR family.|||Binds 1 nickel ion per subunit.|||Transcriptional regulator. http://togogenome.org/gene/1167006:UWK_RS07790 ^@ http://purl.uniprot.org/uniprot/M1P8Z4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS15705 ^@ http://purl.uniprot.org/uniprot/M1PDM3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS00470 ^@ http://purl.uniprot.org/uniprot/M1PA48 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1167006:UWK_RS12385 ^@ http://purl.uniprot.org/uniprot/M1PRR6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1167006:UWK_RS15515 ^@ http://purl.uniprot.org/uniprot/M1PJA6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS02560 ^@ http://purl.uniprot.org/uniprot/M1NBB1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/1167006:UWK_RS12665 ^@ http://purl.uniprot.org/uniprot/M1PRW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS11495 ^@ http://purl.uniprot.org/uniprot/M1NGV1 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1167006:UWK_RS13620 ^@ http://purl.uniprot.org/uniprot/M1PCD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS13015 ^@ http://purl.uniprot.org/uniprot/M1P6S4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1167006:UWK_RS14665 ^@ http://purl.uniprot.org/uniprot/M1PT56 ^@ Function|||Similarity ^@ Belongs to the CobT family.|||Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). http://togogenome.org/gene/1167006:UWK_RS00730 ^@ http://purl.uniprot.org/uniprot/M1PJP8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1167006:UWK_RS10880 ^@ http://purl.uniprot.org/uniprot/M1PGF2 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1167006:UWK_RS16165 ^@ http://purl.uniprot.org/uniprot/M1PJQ2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS00185 ^@ http://purl.uniprot.org/uniprot/M1PA01 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS12405 ^@ http://purl.uniprot.org/uniprot/M1PHF9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1167006:UWK_RS05665 ^@ http://purl.uniprot.org/uniprot/M1ND67 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS14985 ^@ http://purl.uniprot.org/uniprot/M1NJ32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS12835 ^@ http://purl.uniprot.org/uniprot/M1PRZ2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS10295 ^@ http://purl.uniprot.org/uniprot/M1NG29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1167006:UWK_RS10885 ^@ http://purl.uniprot.org/uniprot/M1PQQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14255 ^@ http://purl.uniprot.org/uniprot/M1PSW2 ^@ Subunit ^@ Homotetramer. http://togogenome.org/gene/1167006:UWK_RS03295 ^@ http://purl.uniprot.org/uniprot/M1PL70 ^@ Function ^@ Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif. http://togogenome.org/gene/1167006:UWK_RS09580 ^@ http://purl.uniprot.org/uniprot/M1P4U9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SEDS family. MrdB/RodA subfamily.|||Cell inner membrane|||Membrane|||Peptidoglycan polymerase that is essential for cell wall elongation. http://togogenome.org/gene/1167006:UWK_RS11050 ^@ http://purl.uniprot.org/uniprot/M1NGJ2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1167006:UWK_RS13865 ^@ http://purl.uniprot.org/uniprot/M1PCI5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1167006:UWK_RS01470 ^@ http://purl.uniprot.org/uniprot/M1NAK5 ^@ Function|||Similarity ^@ Belongs to the nucleoside phosphorylase PpnP family.|||Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. http://togogenome.org/gene/1167006:UWK_RS08690 ^@ http://purl.uniprot.org/uniprot/M1PPF3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1167006:UWK_RS13280 ^@ http://purl.uniprot.org/uniprot/M1PHY9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09980 ^@ http://purl.uniprot.org/uniprot/M1PQ93 ^@ Similarity ^@ Belongs to the glycosyltransferase 2 family. http://togogenome.org/gene/1167006:UWK_RS02215 ^@ http://purl.uniprot.org/uniprot/M1NB47 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1167006:UWK_RS04880 ^@ http://purl.uniprot.org/uniprot/M1PM86 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1167006:UWK_RS03465 ^@ http://purl.uniprot.org/uniprot/M1P155 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS12060 ^@ http://purl.uniprot.org/uniprot/M1NH91 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1167006:UWK_RS09390 ^@ http://purl.uniprot.org/uniprot/M1PFK2 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1167006:UWK_RS16585 ^@ http://purl.uniprot.org/uniprot/M1P8R0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1167006:UWK_RS12825 ^@ http://purl.uniprot.org/uniprot/M1NHP8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1167006:UWK_RS12710 ^@ http://purl.uniprot.org/uniprot/M1PRX0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1167006:UWK_RS12610 ^@ http://purl.uniprot.org/uniprot/M1PHK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS10180 ^@ http://purl.uniprot.org/uniprot/M1PQC0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1167006:UWK_RS08045 ^@ http://purl.uniprot.org/uniprot/M1P935 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2A subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS10205 ^@ http://purl.uniprot.org/uniprot/M1PQC4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1167006:UWK_RS05460 ^@ http://purl.uniprot.org/uniprot/M1PD23 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1167006:UWK_RS13785 ^@ http://purl.uniprot.org/uniprot/M1PSJ6 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1167006:UWK_RS15380 ^@ http://purl.uniprot.org/uniprot/M1P827 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1167006:UWK_RS17335 ^@ http://purl.uniprot.org/uniprot/M1PUL5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1167006:UWK_RS05070 ^@ http://purl.uniprot.org/uniprot/M1NCW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1167006:UWK_RS16055 ^@ http://purl.uniprot.org/uniprot/M1P8F2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1167006:UWK_RS01760 ^@ http://purl.uniprot.org/uniprot/M1PKA6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1167006:UWK_RS03405 ^@ http://purl.uniprot.org/uniprot/M1PL89 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS09645 ^@ http://purl.uniprot.org/uniprot/M1PA45 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the band 7/mec-2 family. HflK subfamily.|||HflC and HflK could encode or regulate a protease.|||HflC and HflK may interact to form a multimeric complex.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01975 ^@ http://purl.uniprot.org/uniprot/M1P0F5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1167006:UWK_RS08870 ^@ http://purl.uniprot.org/uniprot/M1P9K9 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1167006:UWK_RS10240 ^@ http://purl.uniprot.org/uniprot/M1P543 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL5 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.|||This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. http://togogenome.org/gene/1167006:UWK_RS15640 ^@ http://purl.uniprot.org/uniprot/M1PJD5 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1167006:UWK_RS11255 ^@ http://purl.uniprot.org/uniprot/M1PQY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS05755 ^@ http://purl.uniprot.org/uniprot/M1P7P5 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1167006:UWK_RS18250 ^@ http://purl.uniprot.org/uniprot/M1P7A4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS09510 ^@ http://purl.uniprot.org/uniprot/M1PFM6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS13555 ^@ http://purl.uniprot.org/uniprot/M1NI61 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1167006:UWK_RS09135 ^@ http://purl.uniprot.org/uniprot/M1NFF5 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1167006:UWK_RS05410 ^@ http://purl.uniprot.org/uniprot/M1ND20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS14165 ^@ http://purl.uniprot.org/uniprot/M1P7E0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS17010 ^@ http://purl.uniprot.org/uniprot/M1PEE7 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1167006:UWK_RS05890 ^@ http://purl.uniprot.org/uniprot/M1PDC7 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1167006:UWK_RS09025 ^@ http://purl.uniprot.org/uniprot/M1P9P2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS06225 ^@ http://purl.uniprot.org/uniprot/M1P2U8 ^@ Similarity ^@ Belongs to the GTP cyclohydrolase I type 2/NIF3 family. http://togogenome.org/gene/1167006:UWK_RS05360 ^@ http://purl.uniprot.org/uniprot/M1ND10 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS10125 ^@ http://purl.uniprot.org/uniprot/M1PFY2 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1167006:UWK_RS09235 ^@ http://purl.uniprot.org/uniprot/M1NFI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1167006:UWK_RS18000 ^@ http://purl.uniprot.org/uniprot/M1P4T7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12775 ^@ http://purl.uniprot.org/uniprot/M1NHN8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS09230 ^@ http://purl.uniprot.org/uniprot/M1P4K7 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS02150 ^@ http://purl.uniprot.org/uniprot/M1PKL1 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1167006:UWK_RS17030 ^@ http://purl.uniprot.org/uniprot/M1PUF2 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1167006:UWK_RS14790 ^@ http://purl.uniprot.org/uniprot/M1PT72 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1167006:UWK_RS11410 ^@ http://purl.uniprot.org/uniprot/M1PB12 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NapD family.|||Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.|||Cytoplasm|||Interacts with the cytoplasmic NapA precursor. http://togogenome.org/gene/1167006:UWK_RS16120 ^@ http://purl.uniprot.org/uniprot/M1PDW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1167006:UWK_RS15850 ^@ http://purl.uniprot.org/uniprot/M1PTP0 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1167006:UWK_RS16520 ^@ http://purl.uniprot.org/uniprot/M1PE43 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS02975 ^@ http://purl.uniprot.org/uniprot/M1PL09 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Mediates influx of magnesium ions.|||Membrane http://togogenome.org/gene/1167006:UWK_RS12540 ^@ http://purl.uniprot.org/uniprot/M1PBR2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1167006:UWK_RS16290 ^@ http://purl.uniprot.org/uniprot/M1PTY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS11875 ^@ http://purl.uniprot.org/uniprot/M1PBB9 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1167006:UWK_RS07895 ^@ http://purl.uniprot.org/uniprot/M1P909 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS03875 ^@ http://purl.uniprot.org/uniprot/M1PC68 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1167006:UWK_RS00340 ^@ http://purl.uniprot.org/uniprot/M1PA25 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1167006:UWK_RS17710 ^@ http://purl.uniprot.org/uniprot/M1PKQ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1167006:UWK_RS08455 ^@ http://purl.uniprot.org/uniprot/M1NEY5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16050 ^@ http://purl.uniprot.org/uniprot/M1PDU7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.|||Binds 1 S-adenosyl-L-methionine per subunit.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS08250 ^@ http://purl.uniprot.org/uniprot/M1P406 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS16030 ^@ http://purl.uniprot.org/uniprot/M1P8E8 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1167006:UWK_RS04415 ^@ http://purl.uniprot.org/uniprot/M1PLX5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS08460 ^@ http://purl.uniprot.org/uniprot/M1PEY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1167006:UWK_RS17285 ^@ http://purl.uniprot.org/uniprot/M1PUK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15370 ^@ http://purl.uniprot.org/uniprot/M1PTG4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of five rings (E,L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1167006:UWK_RS02015 ^@ http://purl.uniprot.org/uniprot/M1P5P7 ^@ Function|||Similarity|||Subunit ^@ A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.|||Belongs to the RecC family.|||Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. http://togogenome.org/gene/1167006:UWK_RS07065 ^@ http://purl.uniprot.org/uniprot/M1PE70 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1167006:UWK_RS04865 ^@ http://purl.uniprot.org/uniprot/M1P241 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS03985 ^@ http://purl.uniprot.org/uniprot/M1PC93 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Acetylates the N-terminal alanine of ribosomal protein S18.|||Belongs to the acetyltransferase family. RimI subfamily.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS18410 ^@ http://purl.uniprot.org/uniprot/M1P944 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1167006:UWK_RS13695 ^@ http://purl.uniprot.org/uniprot/M1PCF1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS12370 ^@ http://purl.uniprot.org/uniprot/M1P6G7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1167006:UWK_RS18320 ^@ http://purl.uniprot.org/uniprot/M1PNC7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS07120 ^@ http://purl.uniprot.org/uniprot/M1PE79 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1167006:UWK_RS05440 ^@ http://purl.uniprot.org/uniprot/M1PMI9 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1167006:UWK_RS00090 ^@ http://purl.uniprot.org/uniprot/M1P4I5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1167006:UWK_RS16130 ^@ http://purl.uniprot.org/uniprot/M1NJM5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Cob(I)alamin adenosyltransferase family.|||Cytoplasm|||Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. http://togogenome.org/gene/1167006:UWK_RS14310 ^@ http://purl.uniprot.org/uniprot/M1PCT5 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1167006:UWK_RS06830 ^@ http://purl.uniprot.org/uniprot/M1NE04 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1167006:UWK_RS04470 ^@ http://purl.uniprot.org/uniprot/M1P1V2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1167006:UWK_RS16885 ^@ http://purl.uniprot.org/uniprot/M1PEC3 ^@ Similarity ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1167006:UWK_RS04500 ^@ http://purl.uniprot.org/uniprot/M1NCK0 ^@ Similarity ^@ Belongs to the oxoprolinase family. http://togogenome.org/gene/1167006:UWK_RS05085 ^@ http://purl.uniprot.org/uniprot/M1P7B9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Membrane|||Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1167006:UWK_RS00045 ^@ http://purl.uniprot.org/uniprot/M1N9R6 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1167006:UWK_RS14305 ^@ http://purl.uniprot.org/uniprot/M1PSX3 ^@ Similarity ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. http://togogenome.org/gene/1167006:UWK_RS02295 ^@ http://purl.uniprot.org/uniprot/M1PBB1 ^@ Similarity ^@ Belongs to the precorrin methyltransferase family. http://togogenome.org/gene/1167006:UWK_RS04495 ^@ http://purl.uniprot.org/uniprot/M1P1V9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the bacterial flagellin family.|||Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.|||Secreted http://togogenome.org/gene/1167006:UWK_RS00215 ^@ http://purl.uniprot.org/uniprot/M1PJF6 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1167006:UWK_RS03625 ^@ http://purl.uniprot.org/uniprot/M1PC09 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00480 ^@ http://purl.uniprot.org/uniprot/M1P4Q3 ^@ Function|||Similarity ^@ Belongs to the phenylacetyl-CoA ligase family.|||Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA). http://togogenome.org/gene/1167006:UWK_RS08540 ^@ http://purl.uniprot.org/uniprot/M1PPC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS10190 ^@ http://purl.uniprot.org/uniprot/M1P534 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1167006:UWK_RS13220 ^@ http://purl.uniprot.org/uniprot/M1NHY3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1167006:UWK_RS15300 ^@ http://purl.uniprot.org/uniprot/M1PDD8 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1167006:UWK_RS09305 ^@ http://purl.uniprot.org/uniprot/M1P4M4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1167006:UWK_RS16650 ^@ http://purl.uniprot.org/uniprot/M1PK00 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1167006:UWK_RS11350 ^@ http://purl.uniprot.org/uniprot/M1PGR0 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.|||Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).|||Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS16580 ^@ http://purl.uniprot.org/uniprot/M1PE53 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1167006:UWK_RS04160 ^@ http://purl.uniprot.org/uniprot/M1P1L9 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1167006:UWK_RS08695 ^@ http://purl.uniprot.org/uniprot/M1P9H2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1167006:UWK_RS10560 ^@ http://purl.uniprot.org/uniprot/M1PQI7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Pal lipoprotein family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1167006:UWK_RS08375 ^@ http://purl.uniprot.org/uniprot/M1P431 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1167006:UWK_RS04190 ^@ http://purl.uniprot.org/uniprot/M1NCA0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS17515 ^@ http://purl.uniprot.org/uniprot/M1P9C5 ^@ Similarity ^@ Belongs to the desulfoferrodoxin family. http://togogenome.org/gene/1167006:UWK_RS02310 ^@ http://purl.uniprot.org/uniprot/M1P0L6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS06235 ^@ http://purl.uniprot.org/uniprot/M1PDL0 ^@ Caution|||Function|||Similarity ^@ Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Belongs to the IspF family.|||Bifunctional enzyme that catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).|||In the C-terminal section; belongs to the IspF family.|||In the N-terminal section; belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS03215 ^@ http://purl.uniprot.org/uniprot/M1PBS1 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1167006:UWK_RS14235 ^@ http://purl.uniprot.org/uniprot/M1PCR7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS13780 ^@ http://purl.uniprot.org/uniprot/M1PI87 ^@ Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family. http://togogenome.org/gene/1167006:UWK_RS14090 ^@ http://purl.uniprot.org/uniprot/M1PCN2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS17645 ^@ http://purl.uniprot.org/uniprot/M1PEU7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1167006:UWK_RS06575 ^@ http://purl.uniprot.org/uniprot/M1P881 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16635 ^@ http://purl.uniprot.org/uniprot/M1PE63 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1167006:UWK_RS11205 ^@ http://purl.uniprot.org/uniprot/M1PGM5 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1167006:UWK_RS12840 ^@ http://purl.uniprot.org/uniprot/M1PBW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS13160 ^@ http://purl.uniprot.org/uniprot/M1PC35 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1167006:UWK_RS14405 ^@ http://purl.uniprot.org/uniprot/M1NIP1 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS15570 ^@ http://purl.uniprot.org/uniprot/M1PTJ3 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1167006:UWK_RS17035 ^@ http://purl.uniprot.org/uniprot/M1PEF3 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1167006:UWK_RS10040 ^@ http://purl.uniprot.org/uniprot/M1P514 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS05345 ^@ http://purl.uniprot.org/uniprot/M1PMH0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS08385 ^@ http://purl.uniprot.org/uniprot/M1PEW1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS01780 ^@ http://purl.uniprot.org/uniprot/M1PAZ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MntP (TC 9.B.29) family.|||Cell inner membrane|||Probably functions as a manganese efflux pump. http://togogenome.org/gene/1167006:UWK_RS14925 ^@ http://purl.uniprot.org/uniprot/M1P7U6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1167006:UWK_RS16970 ^@ http://purl.uniprot.org/uniprot/M1NK24 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1167006:UWK_RS16920 ^@ http://purl.uniprot.org/uniprot/M1NK14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1167006:UWK_RS00295 ^@ http://purl.uniprot.org/uniprot/M1P4M2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS08290 ^@ http://purl.uniprot.org/uniprot/M1PP75 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10540 ^@ http://purl.uniprot.org/uniprot/M1PAI4 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Fur family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03475 ^@ http://purl.uniprot.org/uniprot/M1PBX4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS11905 ^@ http://purl.uniprot.org/uniprot/M1PBC6 ^@ Function|||Similarity ^@ Belongs to the DtxR/MntR family.|||In the presence of manganese, represses expression of mntH and mntS. Up-regulates expression of mntP. http://togogenome.org/gene/1167006:UWK_RS06495 ^@ http://purl.uniprot.org/uniprot/M1PN45 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1167006:UWK_RS13720 ^@ http://purl.uniprot.org/uniprot/M1PSI2 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1167006:UWK_RS16345 ^@ http://purl.uniprot.org/uniprot/M1PE13 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1167006:UWK_RS15265 ^@ http://purl.uniprot.org/uniprot/M1PJ53 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1167006:UWK_RS08785 ^@ http://purl.uniprot.org/uniprot/M1PF54 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1167006:UWK_RS10340 ^@ http://purl.uniprot.org/uniprot/M1P559 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1167006:UWK_RS01285 ^@ http://purl.uniprot.org/uniprot/M1NAG0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS08275 ^@ http://purl.uniprot.org/uniprot/M1P412 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1167006:UWK_RS14570 ^@ http://purl.uniprot.org/uniprot/M1PIQ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1167006:UWK_RS14935 ^@ http://purl.uniprot.org/uniprot/M1PIZ4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1167006:UWK_RS17195 ^@ http://purl.uniprot.org/uniprot/M1P972 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS08580 ^@ http://purl.uniprot.org/uniprot/M1NF19 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS00695 ^@ http://purl.uniprot.org/uniprot/M1NA43 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1167006:UWK_RS06505 ^@ http://purl.uniprot.org/uniprot/M1P315 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1167006:UWK_RS17065 ^@ http://purl.uniprot.org/uniprot/M1P923 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1167006:UWK_RS00335 ^@ http://purl.uniprot.org/uniprot/M1N9X2 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS12970 ^@ http://purl.uniprot.org/uniprot/M1NHT0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS15560 ^@ http://purl.uniprot.org/uniprot/M1NJC4 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. http://togogenome.org/gene/1167006:UWK_RS10300 ^@ http://purl.uniprot.org/uniprot/M1PG15 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1167006:UWK_RS08790 ^@ http://purl.uniprot.org/uniprot/M1PPH6 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1167006:UWK_RS06240 ^@ http://purl.uniprot.org/uniprot/M1PMZ5 ^@ Similarity ^@ Belongs to the peptidase M42 family. http://togogenome.org/gene/1167006:UWK_RS01515 ^@ http://purl.uniprot.org/uniprot/M1P041 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS11860 ^@ http://purl.uniprot.org/uniprot/M1NH39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS02940 ^@ http://purl.uniprot.org/uniprot/M1NBH8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. NspC subfamily.|||Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS00810 ^@ http://purl.uniprot.org/uniprot/M1P4V8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pyridoxamine 5'-phosphate oxidase family.|||Binds 1 FMN per subunit.|||Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03235 ^@ http://purl.uniprot.org/uniprot/M1NBN3 ^@ Similarity ^@ Belongs to the GppA/Ppx family. http://togogenome.org/gene/1167006:UWK_RS03455 ^@ http://purl.uniprot.org/uniprot/M1PLA2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16510 ^@ http://purl.uniprot.org/uniprot/M1PJW7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1167006:UWK_RS03685 ^@ http://purl.uniprot.org/uniprot/M1NBX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1167006:UWK_RS04150 ^@ http://purl.uniprot.org/uniprot/M1PLQ9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1167006:UWK_RS17040 ^@ http://purl.uniprot.org/uniprot/M1P915 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1167006:UWK_RS00320 ^@ http://purl.uniprot.org/uniprot/M1PJH7 ^@ Similarity ^@ Belongs to the UPF0246 family. http://togogenome.org/gene/1167006:UWK_RS07575 ^@ http://purl.uniprot.org/uniprot/M1P3N8 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peroxiredoxin family. Tpx subfamily.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1167006:UWK_RS08355 ^@ http://purl.uniprot.org/uniprot/M1NEV9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS14800 ^@ http://purl.uniprot.org/uniprot/M1P7S3 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1167006:UWK_RS10135 ^@ http://purl.uniprot.org/uniprot/M1PAB4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1167006:UWK_RS12335 ^@ http://purl.uniprot.org/uniprot/M1PHE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12720 ^@ http://purl.uniprot.org/uniprot/M1P6M2 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1167006:UWK_RS13260 ^@ http://purl.uniprot.org/uniprot/M1PS73 ^@ Function|||Similarity ^@ ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.|||Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. http://togogenome.org/gene/1167006:UWK_RS17115 ^@ http://purl.uniprot.org/uniprot/M1PEH2 ^@ Function|||Similarity ^@ Belongs to the folylpolyglutamate synthase family.|||Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives. http://togogenome.org/gene/1167006:UWK_RS01225 ^@ http://purl.uniprot.org/uniprot/M1P539 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12400 ^@ http://purl.uniprot.org/uniprot/M1NHF9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS10145 ^@ http://purl.uniprot.org/uniprot/M1NFZ9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1167006:UWK_RS06370 ^@ http://purl.uniprot.org/uniprot/M1P2Y2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the formate dehydrogenase gamma subunit family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS00385 ^@ http://purl.uniprot.org/uniprot/M1NZH2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the uroporphyrinogen decarboxylase family.|||Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS15205 ^@ http://purl.uniprot.org/uniprot/M1P7Z5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS06955 ^@ http://purl.uniprot.org/uniprot/M1P8H9 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS06775 ^@ http://purl.uniprot.org/uniprot/M1P381 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS10375 ^@ http://purl.uniprot.org/uniprot/M1PG32 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.|||Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03780 ^@ http://purl.uniprot.org/uniprot/M1P1D5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12735 ^@ http://purl.uniprot.org/uniprot/M1PRX6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15945 ^@ http://purl.uniprot.org/uniprot/M1PJK1 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1167006:UWK_RS11975 ^@ http://purl.uniprot.org/uniprot/M1PBE5 ^@ Similarity ^@ Belongs to the UDP-N-acetylglucosamine 2-epimerase family. http://togogenome.org/gene/1167006:UWK_RS15245 ^@ http://purl.uniprot.org/uniprot/M1PTE3 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1167006:UWK_RS15310 ^@ http://purl.uniprot.org/uniprot/M1NJ86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS09460 ^@ http://purl.uniprot.org/uniprot/M1NFM8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS11685 ^@ http://purl.uniprot.org/uniprot/M1P5Z8 ^@ Subcellular Location Annotation ^@ Periplasm http://togogenome.org/gene/1167006:UWK_RS04250 ^@ http://purl.uniprot.org/uniprot/M1PLT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04910 ^@ http://purl.uniprot.org/uniprot/M1P784 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1167006:UWK_RS04465 ^@ http://purl.uniprot.org/uniprot/M1P6Z4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS05435 ^@ http://purl.uniprot.org/uniprot/M1PD19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1167006:UWK_RS12470 ^@ http://purl.uniprot.org/uniprot/M1P6I6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1167006:UWK_RS02460 ^@ http://purl.uniprot.org/uniprot/M1P5W4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1167006:UWK_RS06750 ^@ http://purl.uniprot.org/uniprot/M1P375 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AcsB/BcsB family.|||Binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP).|||Cell inner membrane|||Tightly associated with the cellulose synthase catalytic subunit. http://togogenome.org/gene/1167006:UWK_RS08515 ^@ http://purl.uniprot.org/uniprot/M1PPB8 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1167006:UWK_RS15290 ^@ http://purl.uniprot.org/uniprot/M1PJ58 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1167006:UWK_RS03220 ^@ http://purl.uniprot.org/uniprot/M1PL57 ^@ Function|||Similarity ^@ Belongs to the rubredoxin family.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/1167006:UWK_RS12270 ^@ http://purl.uniprot.org/uniprot/M1PBL7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS01350 ^@ http://purl.uniprot.org/uniprot/M1P568 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS04885 ^@ http://purl.uniprot.org/uniprot/M1P779 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1167006:UWK_RS01630 ^@ http://purl.uniprot.org/uniprot/M1PK74 ^@ Caution|||Cofactor|||Function|||PTM|||Similarity|||Subunit ^@ Belongs to the peroxidase family. Peroxidase/catalase subfamily.|||Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.|||Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS12455 ^@ http://purl.uniprot.org/uniprot/M1PHG9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS03810 ^@ http://purl.uniprot.org/uniprot/M1NC12 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS07085 ^@ http://purl.uniprot.org/uniprot/M1NE78 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAP transporter large permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the tripartite ATP-independent periplasmic (TRAP) transport system.|||The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins. http://togogenome.org/gene/1167006:UWK_RS12480 ^@ http://purl.uniprot.org/uniprot/M1PHH4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS06640 ^@ http://purl.uniprot.org/uniprot/M1PN81 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS08710 ^@ http://purl.uniprot.org/uniprot/M1PF35 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS04005 ^@ http://purl.uniprot.org/uniprot/M1NC57 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS10915 ^@ http://purl.uniprot.org/uniprot/M1PAQ3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the rubredoxin family.|||Binds 1 Fe(3+) ion per subunit.|||Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule. http://togogenome.org/gene/1167006:UWK_RS11520 ^@ http://purl.uniprot.org/uniprot/M1NGV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1167006:UWK_RS06770 ^@ http://purl.uniprot.org/uniprot/M1P8D4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS10330 ^@ http://purl.uniprot.org/uniprot/M1PQE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10790 ^@ http://purl.uniprot.org/uniprot/M1PQN0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS03860 ^@ http://purl.uniprot.org/uniprot/M1P1F4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the HCP family.|||Binds 1 [4Fe-4S] cluster.|||Binds 1 hybrid [4Fe-2O-2S] cluster.|||Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15170 ^@ http://purl.uniprot.org/uniprot/M1PTD2 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1167006:UWK_RS10130 ^@ http://purl.uniprot.org/uniprot/M1PQB3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1167006:UWK_RS10345 ^@ http://purl.uniprot.org/uniprot/M1NG38 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS16540 ^@ http://purl.uniprot.org/uniprot/M1PJX3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1167006:UWK_RS07490 ^@ http://purl.uniprot.org/uniprot/M1PNS7 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1167006:UWK_RS07830 ^@ http://purl.uniprot.org/uniprot/M1PEI5 ^@ Similarity ^@ Belongs to the methylmalonyl-CoA epimerase family. http://togogenome.org/gene/1167006:UWK_RS12670 ^@ http://purl.uniprot.org/uniprot/M1PBT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS05695 ^@ http://purl.uniprot.org/uniprot/M1PD76 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1167006:UWK_RS09605 ^@ http://purl.uniprot.org/uniprot/M1P4V3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS15375 ^@ http://purl.uniprot.org/uniprot/M1PDF6 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1167006:UWK_RS17525 ^@ http://purl.uniprot.org/uniprot/M1PKL5 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS00545 ^@ http://purl.uniprot.org/uniprot/M1NA13 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1167006:UWK_RS14930 ^@ http://purl.uniprot.org/uniprot/M1NJ25 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PRA-CH family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 zinc ion per subunit.|||Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS15180 ^@ http://purl.uniprot.org/uniprot/M1P7Z0 ^@ Cofactor|||Function|||Subunit ^@ Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.|||Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.|||Heterodimer of the IorA and IorB subunits. http://togogenome.org/gene/1167006:UWK_RS17000 ^@ http://purl.uniprot.org/uniprot/M1PK94 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS11705 ^@ http://purl.uniprot.org/uniprot/M1PB77 ^@ Function|||Similarity ^@ Belongs to the NifU family.|||May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. http://togogenome.org/gene/1167006:UWK_RS08015 ^@ http://purl.uniprot.org/uniprot/M1PP22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS16365 ^@ http://purl.uniprot.org/uniprot/M1PU06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1167006:UWK_RS17050 ^@ http://purl.uniprot.org/uniprot/M1PKA7 ^@ Similarity ^@ Belongs to the CbbQ/NirQ/NorQ/GpvN family. http://togogenome.org/gene/1167006:UWK_RS09220 ^@ http://purl.uniprot.org/uniprot/M1PPU2 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1167006:UWK_RS01465 ^@ http://purl.uniprot.org/uniprot/M1P025 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1167006:UWK_RS08815 ^@ http://purl.uniprot.org/uniprot/M1PF59 ^@ Similarity ^@ Belongs to the P(II) protein family. http://togogenome.org/gene/1167006:UWK_RS05385 ^@ http://purl.uniprot.org/uniprot/M1ND14 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1167006:UWK_RS06030 ^@ http://purl.uniprot.org/uniprot/M1P2R4 ^@ Similarity ^@ Belongs to the phosphate/phosphite/phosphonate binding protein family. http://togogenome.org/gene/1167006:UWK_RS11690 ^@ http://purl.uniprot.org/uniprot/M1NGZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS11090 ^@ http://purl.uniprot.org/uniprot/M1NGK3 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1167006:UWK_RS14505 ^@ http://purl.uniprot.org/uniprot/M1PCX5 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1167006:UWK_RS01680 ^@ http://purl.uniprot.org/uniprot/M1PAW5 ^@ Function|||Subunit ^@ Interacts with sigma-54.|||Required for activation of most nif operons, which are directly involved in nitrogen fixation. http://togogenome.org/gene/1167006:UWK_RS10220 ^@ http://purl.uniprot.org/uniprot/M1NG13 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1167006:UWK_RS06735 ^@ http://purl.uniprot.org/uniprot/M1PDY6 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1167006:UWK_RS10325 ^@ http://purl.uniprot.org/uniprot/M1PG21 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1167006:UWK_RS15135 ^@ http://purl.uniprot.org/uniprot/M1P7Y2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1167006:UWK_RS09125 ^@ http://purl.uniprot.org/uniprot/M1P9R7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1167006:UWK_RS15430 ^@ http://purl.uniprot.org/uniprot/M1P835 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/1167006:UWK_RS12890 ^@ http://purl.uniprot.org/uniprot/M1PBX5 ^@ Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. http://togogenome.org/gene/1167006:UWK_RS06525 ^@ http://purl.uniprot.org/uniprot/M1P871 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1167006:UWK_RS17280 ^@ http://purl.uniprot.org/uniprot/M1PKH0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10380 ^@ http://purl.uniprot.org/uniprot/M1PQF6 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1167006:UWK_RS06540 ^@ http://purl.uniprot.org/uniprot/M1PDT8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS02240 ^@ http://purl.uniprot.org/uniprot/M1NB52 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.|||Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.|||Homotetramer. http://togogenome.org/gene/1167006:UWK_RS13985 ^@ http://purl.uniprot.org/uniprot/M1PIC8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS10250 ^@ http://purl.uniprot.org/uniprot/M1NG19 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1167006:UWK_RS17345 ^@ http://purl.uniprot.org/uniprot/M1P998 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1167006:UWK_RS16745 ^@ http://purl.uniprot.org/uniprot/M1P8U7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04235 ^@ http://purl.uniprot.org/uniprot/M1P1N9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS12275 ^@ http://purl.uniprot.org/uniprot/M1P6F0 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1167006:UWK_RS16965 ^@ http://purl.uniprot.org/uniprot/M1P900 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1167006:UWK_RS15525 ^@ http://purl.uniprot.org/uniprot/M1PDI6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04825 ^@ http://purl.uniprot.org/uniprot/M1PCS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS15335 ^@ http://purl.uniprot.org/uniprot/M1NJ91 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliR/MopE/SpaR family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1167006:UWK_RS03555 ^@ http://purl.uniprot.org/uniprot/M1PLC9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16910 ^@ http://purl.uniprot.org/uniprot/M1PEC6 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1167006:UWK_RS14340 ^@ http://purl.uniprot.org/uniprot/M1PCU2 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1167006:UWK_RS15750 ^@ http://purl.uniprot.org/uniprot/M1PTM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS01560 ^@ http://purl.uniprot.org/uniprot/M1PK57 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS15315 ^@ http://purl.uniprot.org/uniprot/M1PJ64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliN/MopA/SpaO family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS08245 ^@ http://purl.uniprot.org/uniprot/M1P971 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1167006:UWK_RS06035 ^@ http://purl.uniprot.org/uniprot/M1NDE0 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1167006:UWK_RS01710 ^@ http://purl.uniprot.org/uniprot/M1PK92 ^@ Function|||Similarity|||Subunit ^@ Belongs to the NifD/NifK/NifE/NifN family.|||Tetramer of two alpha and two beta chains. Forms complex with the iron protein (nitrogenase component 2).|||This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation. http://togogenome.org/gene/1167006:UWK_RS12705 ^@ http://purl.uniprot.org/uniprot/M1PHM3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1167006:UWK_RS15330 ^@ http://purl.uniprot.org/uniprot/M1P817 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1167006:UWK_RS15940 ^@ http://purl.uniprot.org/uniprot/M1NJI8 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1167006:UWK_RS05900 ^@ http://purl.uniprot.org/uniprot/M1P7S7 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1167006:UWK_RS13075 ^@ http://purl.uniprot.org/uniprot/M1PHU8 ^@ Domain|||Function|||Miscellaneous|||Similarity ^@ Belongs to the CobB/CbiA family.|||Belongs to the CobB/CobQ family. CobQ subfamily.|||Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source.|||Comprises of two domains. The C-terminal domain contains the binding site for glutamine and catalyzes the hydrolysis of this substrate to glutamate and ammonia. The N-terminal domain is anticipated to bind ATP and cobyrinate and catalyzes the ultimate synthesis of the diamide product. The ammonia produced via the glutaminase domain is probably translocated to the adjacent domain via a molecular tunnel, where it reacts with an activated intermediate.|||The a and c carboxylates of cobyrinate are activated for nucleophilic attack via formation of a phosphorylated intermediate by ATP. CbiA catalyzes first the amidation of the c-carboxylate, and then that of the a-carboxylate. http://togogenome.org/gene/1167006:UWK_RS05515 ^@ http://purl.uniprot.org/uniprot/M1PD33 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS01415 ^@ http://purl.uniprot.org/uniprot/M1P015 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS18125 ^@ http://purl.uniprot.org/uniprot/M1PL61 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1167006:UWK_RS01455 ^@ http://purl.uniprot.org/uniprot/M1PK35 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1167006:UWK_RS07470 ^@ http://purl.uniprot.org/uniprot/M1P8T8 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1167006:UWK_RS15235 ^@ http://purl.uniprot.org/uniprot/M1NJ73 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1167006:UWK_RS02575 ^@ http://purl.uniprot.org/uniprot/M1P5Y4 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1167006:UWK_RS14025 ^@ http://purl.uniprot.org/uniprot/M1NIG3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1167006:UWK_RS03190 ^@ http://purl.uniprot.org/uniprot/M1PBR6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/1167006:UWK_RS06260 ^@ http://purl.uniprot.org/uniprot/M1PDL8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1167006:UWK_RS15175 ^@ http://purl.uniprot.org/uniprot/M1PDB2 ^@ Cofactor|||Similarity ^@ Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.|||Binds 3 [4Fe-4S] clusters per subunit. http://togogenome.org/gene/1167006:UWK_RS09625 ^@ http://purl.uniprot.org/uniprot/M1PA41 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1167006:UWK_RS05540 ^@ http://purl.uniprot.org/uniprot/M1P2G3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1167006:UWK_RS15885 ^@ http://purl.uniprot.org/uniprot/M1P8B6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS01625 ^@ http://purl.uniprot.org/uniprot/M1NAP6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1167006:UWK_RS18170 ^@ http://purl.uniprot.org/uniprot/M1PC57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1167006:UWK_RS15340 ^@ http://purl.uniprot.org/uniprot/M1PJ69 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1167006:UWK_RS10420 ^@ http://purl.uniprot.org/uniprot/M1PG46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CrcB (TC 9.B.71) family.|||Cell inner membrane|||Important for reducing fluoride concentration in the cell, thus reducing its toxicity.|||Membrane http://togogenome.org/gene/1167006:UWK_RS07455 ^@ http://purl.uniprot.org/uniprot/M1NED6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the desulfoferrodoxin family.|||Catalyzes the one-electron reduction of superoxide anion radical to hydrogen peroxide at a nonheme ferrous iron center. Plays a fundamental role in case of oxidative stress via its superoxide detoxification activity.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS14525 ^@ http://purl.uniprot.org/uniprot/M1PT18 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1167006:UWK_RS02315 ^@ http://purl.uniprot.org/uniprot/M1NB64 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1167006:UWK_RS14455 ^@ http://purl.uniprot.org/uniprot/M1P7K6 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1167006:UWK_RS13375 ^@ http://purl.uniprot.org/uniprot/M1NI19 ^@ Similarity ^@ Belongs to the VgrG protein family. http://togogenome.org/gene/1167006:UWK_RS10395 ^@ http://purl.uniprot.org/uniprot/M1NG49 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1167006:UWK_RS06790 ^@ http://purl.uniprot.org/uniprot/M1PNC0 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1167006:UWK_RS17505 ^@ http://purl.uniprot.org/uniprot/M1PUP5 ^@ Function|||Similarity ^@ Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.|||CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). http://togogenome.org/gene/1167006:UWK_RS00795 ^@ http://purl.uniprot.org/uniprot/M1NA64 ^@ Similarity ^@ Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. http://togogenome.org/gene/1167006:UWK_RS16230 ^@ http://purl.uniprot.org/uniprot/M1P8I7 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1167006:UWK_RS17690 ^@ http://purl.uniprot.org/uniprot/M1PUS5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS17375 ^@ http://purl.uniprot.org/uniprot/M1NKB5 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1167006:UWK_RS11785 ^@ http://purl.uniprot.org/uniprot/M1P625 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1167006:UWK_RS15150 ^@ http://purl.uniprot.org/uniprot/M1PTC7 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1167006:UWK_RS14295 ^@ http://purl.uniprot.org/uniprot/M1NIL9 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1167006:UWK_RS08530 ^@ http://purl.uniprot.org/uniprot/M1NF06 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial diacylglycerol kinase family.|||Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1167006:UWK_RS09540 ^@ http://purl.uniprot.org/uniprot/M1PQ21 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1167006:UWK_RS11840 ^@ http://purl.uniprot.org/uniprot/M1NH33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS08145 ^@ http://purl.uniprot.org/uniprot/M1P954 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1167006:UWK_RS10195 ^@ http://purl.uniprot.org/uniprot/M1NG08 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1167006:UWK_RS07730 ^@ http://purl.uniprot.org/uniprot/M1PEG9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1167006:UWK_RS10165 ^@ http://purl.uniprot.org/uniprot/M1P529 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1167006:UWK_RS10360 ^@ http://purl.uniprot.org/uniprot/M1PAF2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1167006:UWK_RS08955 ^@ http://purl.uniprot.org/uniprot/M1NFB0 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1167006:UWK_RS17680 ^@ http://purl.uniprot.org/uniprot/M1NKG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1167006:UWK_RS15805 ^@ http://purl.uniprot.org/uniprot/M1PDP4 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1167006:UWK_RS09100 ^@ http://purl.uniprot.org/uniprot/M1P9R0 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1167006:UWK_RS05780 ^@ http://purl.uniprot.org/uniprot/M1P7Q0 ^@ Function|||Similarity ^@ Belongs to the carbamoyltransferase HypF family.|||Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. http://togogenome.org/gene/1167006:UWK_RS00925 ^@ http://purl.uniprot.org/uniprot/M1NA87 ^@ Cofactor|||Function ^@ Binds 2 [4Fe-4S] clusters.|||Component of a complex that catalyzes the oxidation of glycolate to glyoxylate. http://togogenome.org/gene/1167006:UWK_RS16085 ^@ http://purl.uniprot.org/uniprot/M1NJL6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS11710 ^@ http://purl.uniprot.org/uniprot/M1P606 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Seems to participate in the biosynthesis of the nitrogenase metalloclusters by providing the inorganic sulfur required for the Fe-S core formation.|||Homodimer. http://togogenome.org/gene/1167006:UWK_RS12395 ^@ http://purl.uniprot.org/uniprot/M1P6H2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS00725 ^@ http://purl.uniprot.org/uniprot/M1PA98 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1167006:UWK_RS17200 ^@ http://purl.uniprot.org/uniprot/M1NK89 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS04475 ^@ http://purl.uniprot.org/uniprot/M1NCI6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1167006:UWK_RS00060 ^@ http://purl.uniprot.org/uniprot/M1P4I1 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1167006:UWK_RS06175 ^@ http://purl.uniprot.org/uniprot/M1NDH0 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1167006:UWK_RS08475 ^@ http://purl.uniprot.org/uniprot/M1P451 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1167006:UWK_RS00190 ^@ http://purl.uniprot.org/uniprot/M1PJF3 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1167006:UWK_RS11145 ^@ http://purl.uniprot.org/uniprot/M1P5L2 ^@ Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family. http://togogenome.org/gene/1167006:UWK_RS00530 ^@ http://purl.uniprot.org/uniprot/M1PJL1 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1167006:UWK_RS15910 ^@ http://purl.uniprot.org/uniprot/M1P8C2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1167006:UWK_RS16870 ^@ http://purl.uniprot.org/uniprot/M1NK04 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1167006:UWK_RS13285 ^@ http://purl.uniprot.org/uniprot/M1PS77 ^@ Similarity ^@ Belongs to the FeoA family. http://togogenome.org/gene/1167006:UWK_RS14880 ^@ http://purl.uniprot.org/uniprot/M1NJ17 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Belongs to the GARS family.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1167006:UWK_RS15415 ^@ http://purl.uniprot.org/uniprot/M1PJ87 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted