http://togogenome.org/gene/1144275:COCOR_RS00005 ^@ http://purl.uniprot.org/uniprot/H8MRW5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1144275:COCOR_RS25920 ^@ http://purl.uniprot.org/uniprot/H8MSU4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS40175 ^@ http://purl.uniprot.org/uniprot/H8MZL2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS32935 ^@ http://purl.uniprot.org/uniprot/H8MW48 ^@ Similarity ^@ Belongs to the TrpF family. http://togogenome.org/gene/1144275:COCOR_RS00690 ^@ http://purl.uniprot.org/uniprot/H8MV04 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS17090 ^@ http://purl.uniprot.org/uniprot/H8MJA6 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1144275:COCOR_RS39360 ^@ http://purl.uniprot.org/uniprot/H8MWD9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.|||Cytoplasm|||GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.|||Monomer. Associates with the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS26690 ^@ http://purl.uniprot.org/uniprot/H8MW01 ^@ Function|||Similarity ^@ Belongs to the anhydro-N-acetylmuramic acid kinase family.|||Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1144275:COCOR_RS36000 ^@ http://purl.uniprot.org/uniprot/H8MIM1 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family. http://togogenome.org/gene/1144275:COCOR_RS32350 ^@ http://purl.uniprot.org/uniprot/H8MT27 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1144275:COCOR_RS15185 ^@ http://purl.uniprot.org/uniprot/H8N1M1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS07730 ^@ http://purl.uniprot.org/uniprot/H8MWX0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS15210 ^@ http://purl.uniprot.org/uniprot/H8N1M6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1144275:COCOR_RS10495 ^@ http://purl.uniprot.org/uniprot/H8MJ07 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS09950 ^@ http://purl.uniprot.org/uniprot/H8MHK4 ^@ Cofactor|||Function|||Similarity ^@ Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).|||Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster. http://togogenome.org/gene/1144275:COCOR_RS13150 ^@ http://purl.uniprot.org/uniprot/H8MTU4 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1144275:COCOR_RS32435 ^@ http://purl.uniprot.org/uniprot/H8MT44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS14335 ^@ http://purl.uniprot.org/uniprot/H8MYL5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS05760 ^@ http://purl.uniprot.org/uniprot/H8MPB8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase RlmH family.|||Cytoplasm|||Homodimer.|||Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA. http://togogenome.org/gene/1144275:COCOR_RS13980 ^@ http://purl.uniprot.org/uniprot/H8MX10 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS32225 ^@ http://purl.uniprot.org/uniprot/H8MT02 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS16245 ^@ http://purl.uniprot.org/uniprot/H8MGJ1 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS06725 ^@ http://purl.uniprot.org/uniprot/H8MTL8 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS09050 ^@ http://purl.uniprot.org/uniprot/H8N1K6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS26475 ^@ http://purl.uniprot.org/uniprot/H8MVV8 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1144275:COCOR_RS04450 ^@ http://purl.uniprot.org/uniprot/H8MK55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S1C family.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS19285 ^@ http://purl.uniprot.org/uniprot/H8MSH1 ^@ Cofactor|||Similarity ^@ Belongs to the carotenoid oxygenase family.|||Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS28285 ^@ http://purl.uniprot.org/uniprot/H8N272 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS14515 ^@ http://purl.uniprot.org/uniprot/H8MYQ1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1144275:COCOR_RS34940 ^@ http://purl.uniprot.org/uniprot/H8MFR8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the kinesin light chain family.|||cytoskeleton http://togogenome.org/gene/1144275:COCOR_RS32180 ^@ http://purl.uniprot.org/uniprot/H8MSZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12170 ^@ http://purl.uniprot.org/uniprot/H8MPJ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS14990 ^@ http://purl.uniprot.org/uniprot/H8N0C6 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1144275:COCOR_RS25310 ^@ http://purl.uniprot.org/uniprot/H8MR89 ^@ Function|||Similarity ^@ Acts on leucine, isoleucine and valine.|||Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS39035 ^@ http://purl.uniprot.org/uniprot/H8MUU1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell outer membrane|||CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin). http://togogenome.org/gene/1144275:COCOR_RS15980 ^@ http://purl.uniprot.org/uniprot/H8MGD8 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1144275:COCOR_RS20965 ^@ http://purl.uniprot.org/uniprot/H8MYW5 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS1 family. http://togogenome.org/gene/1144275:COCOR_RS07820 ^@ http://purl.uniprot.org/uniprot/H8MWY8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS01320 ^@ http://purl.uniprot.org/uniprot/H8MWQ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS11330 ^@ http://purl.uniprot.org/uniprot/H8MLS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BioY family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS30905 ^@ http://purl.uniprot.org/uniprot/H8MNQ3 ^@ Function|||Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family.|||This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. http://togogenome.org/gene/1144275:COCOR_RS19965 ^@ http://purl.uniprot.org/uniprot/H8MU79 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the universal stress protein A family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS05540 ^@ http://purl.uniprot.org/uniprot/H8MP73 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1144275:COCOR_RS37460 ^@ http://purl.uniprot.org/uniprot/H8MP21 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1144275:COCOR_RS07275 ^@ http://purl.uniprot.org/uniprot/H8MVA6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30360 ^@ http://purl.uniprot.org/uniprot/H8ML43 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29450 ^@ http://purl.uniprot.org/uniprot/H8MIA7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS31650 ^@ http://purl.uniprot.org/uniprot/H8MQA1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS24305 ^@ http://purl.uniprot.org/uniprot/H8MM86 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS27895 ^@ http://purl.uniprot.org/uniprot/H8N0T5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS12015 ^@ http://purl.uniprot.org/uniprot/H8MPG4 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1144275:COCOR_RS02680 ^@ http://purl.uniprot.org/uniprot/H8MEK6 ^@ Similarity ^@ Belongs to the gluconokinase GntK/GntV family. http://togogenome.org/gene/1144275:COCOR_RS34075 ^@ http://purl.uniprot.org/uniprot/H8N0W8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS01925 ^@ http://purl.uniprot.org/uniprot/H8MZT2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS16575 ^@ http://purl.uniprot.org/uniprot/H8MHV6 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1144275:COCOR_RS21240 ^@ http://purl.uniprot.org/uniprot/H8N0F4 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS41420 ^@ http://purl.uniprot.org/uniprot/H8MZJ4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FdhD family.|||Cytoplasm|||Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. http://togogenome.org/gene/1144275:COCOR_RS13295 ^@ http://purl.uniprot.org/uniprot/H8MTX3 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS33650 ^@ http://purl.uniprot.org/uniprot/H8MZA1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class II aldolase/RraA-like family.|||Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2-oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions.|||Homotrimer. http://togogenome.org/gene/1144275:COCOR_RS00500 ^@ http://purl.uniprot.org/uniprot/H8MTJ5 ^@ Activity Regulation|||Cofactor|||Function|||Similarity ^@ Allosterically activated by GTP.|||Belongs to the UPRTase family.|||Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.|||Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate. http://togogenome.org/gene/1144275:COCOR_RS12365 ^@ http://purl.uniprot.org/uniprot/H8MQT1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1144275:COCOR_RS16905 ^@ http://purl.uniprot.org/uniprot/H8MJ71 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1144275:COCOR_RS30665 ^@ http://purl.uniprot.org/uniprot/H8MMF3 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1144275:COCOR_RS21290 ^@ http://purl.uniprot.org/uniprot/H8N0G4 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS20415 ^@ http://purl.uniprot.org/uniprot/H8MVU9 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS26180 ^@ http://purl.uniprot.org/uniprot/H8MUB8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SecG family.|||Cell membrane|||Involved in protein export. Participates in an early event of protein translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS36260 ^@ http://purl.uniprot.org/uniprot/H8MJX8 ^@ Function|||Induction|||Similarity ^@ Acts as a chaperone.|||Belongs to the heat shock protein 70 family.|||By stress conditions e.g. heat shock. http://togogenome.org/gene/1144275:COCOR_RS36585 ^@ http://purl.uniprot.org/uniprot/H8ML94 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13050 ^@ http://purl.uniprot.org/uniprot/H8MSE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13675 ^@ http://purl.uniprot.org/uniprot/H8MVH6 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS22620 ^@ http://purl.uniprot.org/uniprot/H8MGQ1 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1144275:COCOR_RS22685 ^@ http://purl.uniprot.org/uniprot/H8MGR4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS25540 ^@ http://purl.uniprot.org/uniprot/H8MRD6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS22560 ^@ http://purl.uniprot.org/uniprot/H8MGN9 ^@ Similarity ^@ Belongs to the isochorismate synthase family. http://togogenome.org/gene/1144275:COCOR_RS11270 ^@ http://purl.uniprot.org/uniprot/H8MLR5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 38 family. http://togogenome.org/gene/1144275:COCOR_RS11725 ^@ http://purl.uniprot.org/uniprot/H8MN53 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1144275:COCOR_RS18675 ^@ http://purl.uniprot.org/uniprot/H8MPR8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the GTP cyclohydrolase II family.|||Binds 1 zinc ion per subunit.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate. http://togogenome.org/gene/1144275:COCOR_RS07945 ^@ http://purl.uniprot.org/uniprot/H8MYE6 ^@ Similarity ^@ Belongs to the FPG family. http://togogenome.org/gene/1144275:COCOR_RS22830 ^@ http://purl.uniprot.org/uniprot/H8MHY9 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.|||Cell inner membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Requires K(+) for maximal activity.|||Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane. http://togogenome.org/gene/1144275:COCOR_RS05830 ^@ http://purl.uniprot.org/uniprot/H8MPD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS31630 ^@ http://purl.uniprot.org/uniprot/H8MQ97 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS36845 ^@ http://purl.uniprot.org/uniprot/H8MMJ6 ^@ Similarity ^@ Belongs to the terpene synthase family. http://togogenome.org/gene/1144275:COCOR_RS24795 ^@ http://purl.uniprot.org/uniprot/H8MNN9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL10 family.|||Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.|||Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1144275:COCOR_RS00100 ^@ http://purl.uniprot.org/uniprot/H8MRY3 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS06940 ^@ http://purl.uniprot.org/uniprot/H8MTR2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS00035 ^@ http://purl.uniprot.org/uniprot/H8MRX1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS21455 ^@ http://purl.uniprot.org/uniprot/H8N0J6 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS31375 ^@ http://purl.uniprot.org/uniprot/H8MQ46 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A24 family.|||Cell inner membrane|||Cell membrane|||Membrane|||Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine. http://togogenome.org/gene/1144275:COCOR_RS05020 ^@ http://purl.uniprot.org/uniprot/H8MLM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.|||Cytoplasm|||Interacts with 100S ribosomes.|||Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. http://togogenome.org/gene/1144275:COCOR_RS21975 ^@ http://purl.uniprot.org/uniprot/H8N211 ^@ Similarity ^@ Belongs to the peptidase S45 family. http://togogenome.org/gene/1144275:COCOR_RS08390 ^@ http://purl.uniprot.org/uniprot/H8N018 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 5 (cellulase A) family. http://togogenome.org/gene/1144275:COCOR_RS32945 ^@ http://purl.uniprot.org/uniprot/H8MW50 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpA family.|||Tetramer of two alpha and two beta chains.|||The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. http://togogenome.org/gene/1144275:COCOR_RS31320 ^@ http://purl.uniprot.org/uniprot/H8MQ35 ^@ Function ^@ This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1144275:COCOR_RS38510 ^@ http://purl.uniprot.org/uniprot/H8MT65 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS35795 ^@ http://purl.uniprot.org/uniprot/H8MII0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS26850 ^@ http://purl.uniprot.org/uniprot/H8MXF8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 2 lipoyl cofactors covalently.|||Forms a 24-polypeptide structural core with octahedral symmetry.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). http://togogenome.org/gene/1144275:COCOR_RS17745 ^@ http://purl.uniprot.org/uniprot/H8MLY5 ^@ Cofactor|||Function|||PTM|||Similarity ^@ Activated by phosphorylation.|||Belongs to the phosphohexose mutase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate. http://togogenome.org/gene/1144275:COCOR_RS26035 ^@ http://purl.uniprot.org/uniprot/H8MU92 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1144275:COCOR_RS08945 ^@ http://purl.uniprot.org/uniprot/H8N1I5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS20950 ^@ http://purl.uniprot.org/uniprot/H8MYW2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS10020 ^@ http://purl.uniprot.org/uniprot/H8MHL8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1144275:COCOR_RS15215 ^@ http://purl.uniprot.org/uniprot/H8N1M7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL16 family.|||Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS32310 ^@ http://purl.uniprot.org/uniprot/H8MT19 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1144275:COCOR_RS28410 ^@ http://purl.uniprot.org/uniprot/H8N297 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0382 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS01115 ^@ http://purl.uniprot.org/uniprot/H8MWK9 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1144275:COCOR_RS34650 ^@ http://purl.uniprot.org/uniprot/H8N2E1 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS05195 ^@ http://purl.uniprot.org/uniprot/H8MMV4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS16600 ^@ http://purl.uniprot.org/uniprot/H8MHW0 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1144275:COCOR_RS11915 ^@ http://purl.uniprot.org/uniprot/H8MPE4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ArgR family.|||Cytoplasm|||Regulates arginine biosynthesis genes. http://togogenome.org/gene/1144275:COCOR_RS36445 ^@ http://purl.uniprot.org/uniprot/H8ML66 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04730 ^@ http://purl.uniprot.org/uniprot/H8MLG2 ^@ Similarity ^@ Belongs to the glutamate synthase family. http://togogenome.org/gene/1144275:COCOR_RS35570 ^@ http://purl.uniprot.org/uniprot/H8MH91 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30680 ^@ http://purl.uniprot.org/uniprot/H8MMF6 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS14525 ^@ http://purl.uniprot.org/uniprot/H8MYQ3 ^@ Similarity ^@ Belongs to the UDPGP type 1 family. http://togogenome.org/gene/1144275:COCOR_RS05055 ^@ http://purl.uniprot.org/uniprot/H8MMS6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS23300 ^@ http://purl.uniprot.org/uniprot/H8MJD9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS22535 ^@ http://purl.uniprot.org/uniprot/H8MGN4 ^@ Function|||Similarity ^@ Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily.|||Converts 2-succinylbenzoate (OSB) to 2-succinylbenzoyl-CoA (OSB-CoA). http://togogenome.org/gene/1144275:COCOR_RS10995 ^@ http://purl.uniprot.org/uniprot/H8MKF8 ^@ Function|||Similarity ^@ Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.|||DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes. http://togogenome.org/gene/1144275:COCOR_RS24805 ^@ http://purl.uniprot.org/uniprot/H8MNP1 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1144275:COCOR_RS04540 ^@ http://purl.uniprot.org/uniprot/H8MK74 ^@ Function|||Similarity|||Subunit ^@ Belongs to the 6-phosphogluconate dehydrogenase family.|||Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS24030 ^@ http://purl.uniprot.org/uniprot/H8MKY2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.|||Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS03430 ^@ http://purl.uniprot.org/uniprot/H8MG54 ^@ Similarity ^@ Belongs to the peptidase M4 family. http://togogenome.org/gene/1144275:COCOR_RS13505 ^@ http://purl.uniprot.org/uniprot/H8MVE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1144275:COCOR_RS15635 ^@ http://purl.uniprot.org/uniprot/H8MF28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS25120 ^@ http://purl.uniprot.org/uniprot/H8MPZ9 ^@ Function|||Similarity ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.|||Necessary for normal cell division and for the maintenance of normal septation. http://togogenome.org/gene/1144275:COCOR_RS28380 ^@ http://purl.uniprot.org/uniprot/H8N291 ^@ Similarity ^@ Belongs to the peptidase M4 family. http://togogenome.org/gene/1144275:COCOR_RS20525 ^@ http://purl.uniprot.org/uniprot/H8MX95 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1144275:COCOR_RS32825 ^@ http://purl.uniprot.org/uniprot/H8MFD2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS34550 ^@ http://purl.uniprot.org/uniprot/H8N2C1 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1144275:COCOR_RS22975 ^@ http://purl.uniprot.org/uniprot/H8MI20 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS40350 ^@ http://purl.uniprot.org/uniprot/H8MZP6 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS01745 ^@ http://purl.uniprot.org/uniprot/H8MYB5 ^@ Function|||Similarity ^@ Belongs to the MsrA Met sulfoxide reductase family.|||Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. http://togogenome.org/gene/1144275:COCOR_RS14105 ^@ http://purl.uniprot.org/uniprot/H8MX35 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS28705 ^@ http://purl.uniprot.org/uniprot/H8MFM2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/UDP phosphorylase family.|||Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.|||Homohexamer; trimer of homodimers. http://togogenome.org/gene/1144275:COCOR_RS26985 ^@ http://purl.uniprot.org/uniprot/H8MXI5 ^@ Function|||Similarity ^@ Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.|||Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis. http://togogenome.org/gene/1144275:COCOR_RS18780 ^@ http://purl.uniprot.org/uniprot/H8MPU0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS33780 ^@ http://purl.uniprot.org/uniprot/H8MZC7 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1144275:COCOR_RS22335 ^@ http://purl.uniprot.org/uniprot/H8MFF0 ^@ Similarity ^@ Belongs to the type IB topoisomerase family. http://togogenome.org/gene/1144275:COCOR_RS33180 ^@ http://purl.uniprot.org/uniprot/H8MW97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS16265 ^@ http://purl.uniprot.org/uniprot/H8MGJ5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS05840 ^@ http://purl.uniprot.org/uniprot/H8MPD4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.|||Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS23835 ^@ http://purl.uniprot.org/uniprot/H8MKU3 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1144275:COCOR_RS14905 ^@ http://purl.uniprot.org/uniprot/H8N0A8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gluconeogenesis factor family.|||Cytoplasm|||Required for morphogenesis under gluconeogenic growth conditions. http://togogenome.org/gene/1144275:COCOR_RS35075 ^@ http://purl.uniprot.org/uniprot/H8MFU5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1144275:COCOR_RS34615 ^@ http://purl.uniprot.org/uniprot/H8N2D4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS02100 ^@ http://purl.uniprot.org/uniprot/H8MZW6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS24655 ^@ http://purl.uniprot.org/uniprot/H8MNL1 ^@ Similarity ^@ Belongs to the UPF0235 family. http://togogenome.org/gene/1144275:COCOR_RS02560 ^@ http://purl.uniprot.org/uniprot/H8N1B3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS34985 ^@ http://purl.uniprot.org/uniprot/H8MFS7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M15D family.|||Binds 1 zinc ion per subunit.|||Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. http://togogenome.org/gene/1144275:COCOR_RS35225 ^@ http://purl.uniprot.org/uniprot/H8MFX5 ^@ Similarity ^@ Belongs to the DNA glycosylase MPG family. http://togogenome.org/gene/1144275:COCOR_RS10840 ^@ http://purl.uniprot.org/uniprot/H8MKC6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS13610 ^@ http://purl.uniprot.org/uniprot/H8MVG3 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1144275:COCOR_RS08345 ^@ http://purl.uniprot.org/uniprot/H8N009 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS02070 ^@ http://purl.uniprot.org/uniprot/H8MZW0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS24930 ^@ http://purl.uniprot.org/uniprot/H8MPW3 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS12030 ^@ http://purl.uniprot.org/uniprot/H8MPG7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1144275:COCOR_RS14285 ^@ http://purl.uniprot.org/uniprot/H8MX73 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1144275:COCOR_RS14730 ^@ http://purl.uniprot.org/uniprot/H8N074 ^@ Function|||Similarity ^@ Belongs to the relA/spoT family.|||In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. http://togogenome.org/gene/1144275:COCOR_RS03340 ^@ http://purl.uniprot.org/uniprot/H8MG38 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1144275:COCOR_RS30270 ^@ http://purl.uniprot.org/uniprot/H8ML24 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS19480 ^@ http://purl.uniprot.org/uniprot/H8MSL0 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1144275:COCOR_RS12060 ^@ http://purl.uniprot.org/uniprot/H8MPH3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MIP/aquaporin (TC 1.A.8) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30590 ^@ http://purl.uniprot.org/uniprot/H8MMD8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS13495 ^@ http://purl.uniprot.org/uniprot/H8MU09 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YajC family.|||Cell inner membrane|||Membrane|||Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).|||The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. http://togogenome.org/gene/1144275:COCOR_RS03940 ^@ http://purl.uniprot.org/uniprot/H8MIQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS27370 ^@ http://purl.uniprot.org/uniprot/H8MZ45 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNase HII family.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding. http://togogenome.org/gene/1144275:COCOR_RS31185 ^@ http://purl.uniprot.org/uniprot/H8MNW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily.|||Cell inner membrane|||Homodimer. Forms a membrane-associated complex with FtsX.|||Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring. http://togogenome.org/gene/1144275:COCOR_RS06625 ^@ http://purl.uniprot.org/uniprot/H8MS73 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS32765 ^@ http://purl.uniprot.org/uniprot/H8MUN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ClpS family.|||Binds to the N-terminal domain of the chaperone ClpA.|||Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. http://togogenome.org/gene/1144275:COCOR_RS31225 ^@ http://purl.uniprot.org/uniprot/H8MNW8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TolB family.|||Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.|||Periplasm|||The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer. http://togogenome.org/gene/1144275:COCOR_RS19485 ^@ http://purl.uniprot.org/uniprot/H8MSL1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS15900 ^@ http://purl.uniprot.org/uniprot/H8MF81 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS15220 ^@ http://purl.uniprot.org/uniprot/H8N1M8 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1144275:COCOR_RS27935 ^@ http://purl.uniprot.org/uniprot/H8N0U3 ^@ Similarity ^@ Belongs to the type II topoisomerase GyrB family. http://togogenome.org/gene/1144275:COCOR_RS30700 ^@ http://purl.uniprot.org/uniprot/H8MMG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YscJ lipoprotein family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS09640 ^@ http://purl.uniprot.org/uniprot/H8MG92 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1144275:COCOR_RS30475 ^@ http://purl.uniprot.org/uniprot/H8MMB5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS26365 ^@ http://purl.uniprot.org/uniprot/H8MUF5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1144275:COCOR_RS24815 ^@ http://purl.uniprot.org/uniprot/H8MNP3 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the SecE/SEC61-gamma family.|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS19960 ^@ http://purl.uniprot.org/uniprot/H8MU78 ^@ Cofactor ^@ Binds 1 Fe(2+) ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS36235 ^@ http://purl.uniprot.org/uniprot/H8MJX3 ^@ Similarity ^@ Belongs to the leucine-binding protein family. http://togogenome.org/gene/1144275:COCOR_RS07405 ^@ http://purl.uniprot.org/uniprot/H8MVD1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS22175 ^@ http://purl.uniprot.org/uniprot/H8MFB9 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1144275:COCOR_RS15675 ^@ http://purl.uniprot.org/uniprot/H8MF36 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1144275:COCOR_RS06315 ^@ http://purl.uniprot.org/uniprot/H8MS10 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1144275:COCOR_RS29940 ^@ http://purl.uniprot.org/uniprot/H8MJR1 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS39985 ^@ http://purl.uniprot.org/uniprot/H8MY41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12005 ^@ http://purl.uniprot.org/uniprot/H8MPG2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1144275:COCOR_RS31945 ^@ http://purl.uniprot.org/uniprot/H8MRL2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1144275:COCOR_RS13260 ^@ http://purl.uniprot.org/uniprot/H8MTW6 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1144275:COCOR_RS35065 ^@ http://purl.uniprot.org/uniprot/H8MFU3 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS08060 ^@ http://purl.uniprot.org/uniprot/H8MYH1 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1144275:COCOR_RS26615 ^@ http://purl.uniprot.org/uniprot/H8MVY6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LptD family.|||Cell outer membrane|||Component of the lipopolysaccharide transport and assembly complex.|||Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS38110 ^@ http://purl.uniprot.org/uniprot/H8MRP9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Lgt family.|||Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS15275 ^@ http://purl.uniprot.org/uniprot/H8N1N9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS04525 ^@ http://purl.uniprot.org/uniprot/H8MK71 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS31970 ^@ http://purl.uniprot.org/uniprot/H8MRL7 ^@ Function|||Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family.|||Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. http://togogenome.org/gene/1144275:COCOR_RS18770 ^@ http://purl.uniprot.org/uniprot/H8MPT8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS01620 ^@ http://purl.uniprot.org/uniprot/H8MY90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial solute-binding protein 1 family.|||Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS15270 ^@ http://purl.uniprot.org/uniprot/H8N1N8 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS24300 ^@ http://purl.uniprot.org/uniprot/H8MM85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS04235 ^@ http://purl.uniprot.org/uniprot/H8MK12 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS37085 ^@ http://purl.uniprot.org/uniprot/H8MMP4 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1144275:COCOR_RS38115 ^@ http://purl.uniprot.org/uniprot/H8MRQ0 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1144275:COCOR_RS05235 ^@ http://purl.uniprot.org/uniprot/H8MMW2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS27775 ^@ http://purl.uniprot.org/uniprot/H8N0R0 ^@ Similarity ^@ Belongs to the pseudomonas-type ThrB family. http://togogenome.org/gene/1144275:COCOR_RS35530 ^@ http://purl.uniprot.org/uniprot/H8MH83 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers. http://togogenome.org/gene/1144275:COCOR_RS25110 ^@ http://purl.uniprot.org/uniprot/H8MPZ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS20660 ^@ http://purl.uniprot.org/uniprot/H8MXC3 ^@ Similarity ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. http://togogenome.org/gene/1144275:COCOR_RS11095 ^@ http://purl.uniprot.org/uniprot/H8MLN0 ^@ Similarity ^@ Belongs to the frataxin family. http://togogenome.org/gene/1144275:COCOR_RS26195 ^@ http://purl.uniprot.org/uniprot/H8MUC1 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS21870 ^@ http://purl.uniprot.org/uniprot/H8N1Z0 ^@ Similarity ^@ Belongs to the class-II DAHP synthase family. http://togogenome.org/gene/1144275:COCOR_RS37575 ^@ http://purl.uniprot.org/uniprot/H8MP44 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS10140 ^@ http://purl.uniprot.org/uniprot/H8MHN6 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1144275:COCOR_RS05370 ^@ http://purl.uniprot.org/uniprot/H8MMY9 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1144275:COCOR_RS10025 ^@ http://purl.uniprot.org/uniprot/H8MHL9 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1144275:COCOR_RS00520 ^@ http://purl.uniprot.org/uniprot/H8MTJ9 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1144275:COCOR_RS29175 ^@ http://purl.uniprot.org/uniprot/H8MH09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS28240 ^@ http://purl.uniprot.org/uniprot/H8N263 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1144275:COCOR_RS40430 ^@ http://purl.uniprot.org/uniprot/H8N142 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0161 family.|||Cell inner membrane|||Could be involved in insertion of integral membrane proteins into the membrane. http://togogenome.org/gene/1144275:COCOR_RS13330 ^@ http://purl.uniprot.org/uniprot/H8MTY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxA subfamily.|||Cytoplasm|||Homotrimer.|||Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1144275:COCOR_RS13220 ^@ http://purl.uniprot.org/uniprot/H8MTV8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS19685 ^@ http://purl.uniprot.org/uniprot/H8MU23 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1144275:COCOR_RS07660 ^@ http://purl.uniprot.org/uniprot/H8MWV5 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1144275:COCOR_RS22550 ^@ http://purl.uniprot.org/uniprot/H8MGN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the AB hydrolase superfamily. MenH family.|||Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS38070 ^@ http://purl.uniprot.org/uniprot/H8MRP1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS24800 ^@ http://purl.uniprot.org/uniprot/H8MNP0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1144275:COCOR_RS05050 ^@ http://purl.uniprot.org/uniprot/H8MMS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS15160 ^@ http://purl.uniprot.org/uniprot/H8N1L6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS12 family.|||Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.|||With S4 and S5 plays an important role in translational accuracy. http://togogenome.org/gene/1144275:COCOR_RS06815 ^@ http://purl.uniprot.org/uniprot/H8MTN6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatC family.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1144275:COCOR_RS25875 ^@ http://purl.uniprot.org/uniprot/H8MST5 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1144275:COCOR_RS18930 ^@ http://purl.uniprot.org/uniprot/H8MR15 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37775 ^@ http://purl.uniprot.org/uniprot/H8MQD1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS05205 ^@ http://purl.uniprot.org/uniprot/H8MMV6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30500 ^@ http://purl.uniprot.org/uniprot/H8MMC0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1144275:COCOR_RS11190 ^@ http://purl.uniprot.org/uniprot/H8MLP9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS19130 ^@ http://purl.uniprot.org/uniprot/H8MR56 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS08835 ^@ http://purl.uniprot.org/uniprot/H8N1G3 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS36225 ^@ http://purl.uniprot.org/uniprot/H8MJX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS12025 ^@ http://purl.uniprot.org/uniprot/H8MPG6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1144275:COCOR_RS21035 ^@ http://purl.uniprot.org/uniprot/H8MYX9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS12735 ^@ http://purl.uniprot.org/uniprot/H8MS89 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1144275:COCOR_RS14890 ^@ http://purl.uniprot.org/uniprot/H8N0A5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS40045 ^@ http://purl.uniprot.org/uniprot/H8MZI5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS01570 ^@ http://purl.uniprot.org/uniprot/H8MY80 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS07720 ^@ http://purl.uniprot.org/uniprot/H8MWW8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22475 ^@ http://purl.uniprot.org/uniprot/H8MGM2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase beta subunit family.|||Binds 1 Mg(2+) ion per subunit.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. http://togogenome.org/gene/1144275:COCOR_RS21640 ^@ http://purl.uniprot.org/uniprot/H8N1U3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS09660 ^@ http://purl.uniprot.org/uniprot/H8MG96 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1144275:COCOR_RS39050 ^@ http://purl.uniprot.org/uniprot/H8MUU4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS04550 ^@ http://purl.uniprot.org/uniprot/H8MK76 ^@ Caution|||Function|||Similarity ^@ Belongs to the glucose-6-phosphate dehydrogenase family.|||Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS16580 ^@ http://purl.uniprot.org/uniprot/H8MHV7 ^@ Similarity ^@ Belongs to the FBPase class 2 family. http://togogenome.org/gene/1144275:COCOR_RS36705 ^@ http://purl.uniprot.org/uniprot/H8MLB8 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1144275:COCOR_RS36140 ^@ http://purl.uniprot.org/uniprot/H8MJV4 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1144275:COCOR_RS14000 ^@ http://purl.uniprot.org/uniprot/H8MX14 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS18165 ^@ http://purl.uniprot.org/uniprot/H8MNB8 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS13100 ^@ http://purl.uniprot.org/uniprot/H8MSF7 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1144275:COCOR_RS28140 ^@ http://purl.uniprot.org/uniprot/H8N243 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the YscJ lipoprotein family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03775 ^@ http://purl.uniprot.org/uniprot/H8MHH3 ^@ Function|||Similarity ^@ Belongs to the SELO family.|||Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). http://togogenome.org/gene/1144275:COCOR_RS22160 ^@ http://purl.uniprot.org/uniprot/H8MFB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial histone-like protein family.|||Heterodimer of an alpha and a beta chain.|||This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. http://togogenome.org/gene/1144275:COCOR_RS26935 ^@ http://purl.uniprot.org/uniprot/H8MXH5 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1144275:COCOR_RS25790 ^@ http://purl.uniprot.org/uniprot/H8MSR8 ^@ Similarity ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family. http://togogenome.org/gene/1144275:COCOR_RS06685 ^@ http://purl.uniprot.org/uniprot/H8MTL0 ^@ Similarity ^@ Belongs to the bacterial histone-like protein family. http://togogenome.org/gene/1144275:COCOR_RS22225 ^@ http://purl.uniprot.org/uniprot/H8MFC8 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1144275:COCOR_RS14090 ^@ http://purl.uniprot.org/uniprot/H8MX32 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS12605 ^@ http://purl.uniprot.org/uniprot/H8MQX8 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SMC family.|||Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.|||Cytoplasm|||Homodimer.|||Required for chromosome condensation and partitioning. http://togogenome.org/gene/1144275:COCOR_RS01690 ^@ http://purl.uniprot.org/uniprot/H8MYA4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II FruAB PTS system is involved in fructose transport. http://togogenome.org/gene/1144275:COCOR_RS32770 ^@ http://purl.uniprot.org/uniprot/H8MUN5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1144275:COCOR_RS39920 ^@ http://purl.uniprot.org/uniprot/H8MY28 ^@ Cofactor ^@ Binds 1 FAD per subunit. http://togogenome.org/gene/1144275:COCOR_RS40400 ^@ http://purl.uniprot.org/uniprot/H8MZQ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS12210 ^@ http://purl.uniprot.org/uniprot/H8MPK3 ^@ Subcellular Location Annotation ^@ Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS10070 ^@ http://purl.uniprot.org/uniprot/H8MHM8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNase PH family.|||Homohexameric ring arranged as a trimer of dimers.|||Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. http://togogenome.org/gene/1144275:COCOR_RS24505 ^@ http://purl.uniprot.org/uniprot/H8MNH8 ^@ Similarity ^@ Belongs to the biopterin-dependent aromatic amino acid hydroxylase family. http://togogenome.org/gene/1144275:COCOR_RS04215 ^@ http://purl.uniprot.org/uniprot/H8MIV5 ^@ Similarity ^@ Belongs to the peptidase C59 family. http://togogenome.org/gene/1144275:COCOR_RS19310 ^@ http://purl.uniprot.org/uniprot/H8MSH6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS26320 ^@ http://purl.uniprot.org/uniprot/H8MUE6 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS37080 ^@ http://purl.uniprot.org/uniprot/H8MMP3 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1144275:COCOR_RS10950 ^@ http://purl.uniprot.org/uniprot/H8MKE8 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS28280 ^@ http://purl.uniprot.org/uniprot/H8N271 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1144275:COCOR_RS25295 ^@ http://purl.uniprot.org/uniprot/H8MR86 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS13105 ^@ http://purl.uniprot.org/uniprot/H8MTT5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS28580 ^@ http://purl.uniprot.org/uniprot/H8MFJ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the xanthine dehydrogenase family.|||Peroxisome http://togogenome.org/gene/1144275:COCOR_RS25835 ^@ http://purl.uniprot.org/uniprot/H8MSS7 ^@ Similarity ^@ Belongs to the C/M/P thioester hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS32125 ^@ http://purl.uniprot.org/uniprot/H8MSY1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatC family.|||Cell inner membrane|||Membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1144275:COCOR_RS04140 ^@ http://purl.uniprot.org/uniprot/H8MIU0 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1144275:COCOR_RS35500 ^@ http://purl.uniprot.org/uniprot/H8MH77 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS33190 ^@ http://purl.uniprot.org/uniprot/H8MW99 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS04715 ^@ http://purl.uniprot.org/uniprot/H8MLF9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ammonia transporter channel (TC 1.A.11.2) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS27690 ^@ http://purl.uniprot.org/uniprot/H8N0P2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. TCR/Tet family.|||Membrane|||Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter. http://togogenome.org/gene/1144275:COCOR_RS10320 ^@ http://purl.uniprot.org/uniprot/H8MIX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04345 ^@ http://purl.uniprot.org/uniprot/H8MK34 ^@ Function|||Similarity ^@ Belongs to the aromatic-ring hydroxylase family. KMO subfamily.|||Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. http://togogenome.org/gene/1144275:COCOR_RS05135 ^@ http://purl.uniprot.org/uniprot/H8MMU2 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1144275:COCOR_RS15305 ^@ http://purl.uniprot.org/uniprot/H8N1P4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS13 family.|||Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.|||Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome. http://togogenome.org/gene/1144275:COCOR_RS24735 ^@ http://purl.uniprot.org/uniprot/H8MNM7 ^@ Similarity ^@ Belongs to the carbohydrate kinase PfkB family. http://togogenome.org/gene/1144275:COCOR_RS34420 ^@ http://purl.uniprot.org/uniprot/H8N137 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1144275:COCOR_RS00410 ^@ http://purl.uniprot.org/uniprot/H8MTH6 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome|||Secreted http://togogenome.org/gene/1144275:COCOR_RS26030 ^@ http://purl.uniprot.org/uniprot/H8MSW8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS19385 ^@ http://purl.uniprot.org/uniprot/H8MSJ1 ^@ Similarity ^@ Belongs to the FKBP-type PPIase family. http://togogenome.org/gene/1144275:COCOR_RS19345 ^@ http://purl.uniprot.org/uniprot/H8MSI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS25235 ^@ http://purl.uniprot.org/uniprot/H8MQ22 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08440 ^@ http://purl.uniprot.org/uniprot/H8N029 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS15235 ^@ http://purl.uniprot.org/uniprot/H8N1N1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS32200 ^@ http://purl.uniprot.org/uniprot/H8MSZ7 ^@ Similarity ^@ Belongs to the ThrE exporter (TC 2.A.79) family. http://togogenome.org/gene/1144275:COCOR_RS21600 ^@ http://purl.uniprot.org/uniprot/H8N0M7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS05150 ^@ http://purl.uniprot.org/uniprot/H8MMU5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1144275:COCOR_RS02585 ^@ http://purl.uniprot.org/uniprot/H8N1B8 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1144275:COCOR_RS24500 ^@ http://purl.uniprot.org/uniprot/H8MNH7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS33660 ^@ http://purl.uniprot.org/uniprot/H8MZA3 ^@ Similarity ^@ Belongs to the catalase family. http://togogenome.org/gene/1144275:COCOR_RS23685 ^@ http://purl.uniprot.org/uniprot/H8MKR3 ^@ Similarity ^@ Belongs to the UPF0111 family. http://togogenome.org/gene/1144275:COCOR_RS06015 ^@ http://purl.uniprot.org/uniprot/H8MQL6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L/F-transferase family.|||Cytoplasm|||Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine. http://togogenome.org/gene/1144275:COCOR_RS12190 ^@ http://purl.uniprot.org/uniprot/H8MPJ9 ^@ Similarity ^@ Belongs to the HMG-CoA reductase family. http://togogenome.org/gene/1144275:COCOR_RS28100 ^@ http://purl.uniprot.org/uniprot/H8N235 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliP/MopC/SpaP family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS20410 ^@ http://purl.uniprot.org/uniprot/H8MVU8 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS33175 ^@ http://purl.uniprot.org/uniprot/H8MW96 ^@ Function|||Similarity|||Subunit ^@ Belongs to the ribose 5-phosphate isomerase family.|||Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS09745 ^@ http://purl.uniprot.org/uniprot/H8MGB3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the YbaB/EbfC family.|||Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.|||Homodimer.|||nucleoid http://togogenome.org/gene/1144275:COCOR_RS35930 ^@ http://purl.uniprot.org/uniprot/H8MIK7 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS17755 ^@ http://purl.uniprot.org/uniprot/H8MLY7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the P-Pant transferase superfamily. AcpS family.|||Cytoplasm|||Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. http://togogenome.org/gene/1144275:COCOR_RS02125 ^@ http://purl.uniprot.org/uniprot/H8MZX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS17360 ^@ http://purl.uniprot.org/uniprot/H8MKL0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS08140 ^@ http://purl.uniprot.org/uniprot/H8MYI7 ^@ Similarity ^@ Belongs to the EndA/NucM nuclease family. http://togogenome.org/gene/1144275:COCOR_RS33735 ^@ http://purl.uniprot.org/uniprot/H8MZB8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS27730 ^@ http://purl.uniprot.org/uniprot/H8N0Q0 ^@ Similarity ^@ Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. http://togogenome.org/gene/1144275:COCOR_RS02900 ^@ http://purl.uniprot.org/uniprot/H8MEQ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29030 ^@ http://purl.uniprot.org/uniprot/H8MGY2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS14175 ^@ http://purl.uniprot.org/uniprot/H8MX49 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS26805 ^@ http://purl.uniprot.org/uniprot/H8MW24 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS21795 ^@ http://purl.uniprot.org/uniprot/H8N1X4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS19465 ^@ http://purl.uniprot.org/uniprot/H8MSK7 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS07785 ^@ http://purl.uniprot.org/uniprot/H8MWY2 ^@ Function|||Subcellular Location Annotation ^@ May play a structural or regulatory role in gas vesicle synthesis.|||Vesicle|||gas vesicle http://togogenome.org/gene/1144275:COCOR_RS35920 ^@ http://purl.uniprot.org/uniprot/H8MIK5 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS33570 ^@ http://purl.uniprot.org/uniprot/H8MXV3 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS28125 ^@ http://purl.uniprot.org/uniprot/H8N240 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS28550 ^@ http://purl.uniprot.org/uniprot/H8MFJ2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1144275:COCOR_RS28080 ^@ http://purl.uniprot.org/uniprot/H8N231 ^@ Similarity ^@ Belongs to the type III secretion exporter family. http://togogenome.org/gene/1144275:COCOR_RS02895 ^@ http://purl.uniprot.org/uniprot/H8MEP9 ^@ Similarity ^@ Belongs to the NADH dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS35805 ^@ http://purl.uniprot.org/uniprot/H8MII2 ^@ Function|||Similarity ^@ Antitoxin component of a type II toxin-antitoxin (TA) system.|||Belongs to the phD/YefM antitoxin family. http://togogenome.org/gene/1144275:COCOR_RS04430 ^@ http://purl.uniprot.org/uniprot/H8MK51 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS19400 ^@ http://purl.uniprot.org/uniprot/H8MSJ4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. http://togogenome.org/gene/1144275:COCOR_RS24480 ^@ http://purl.uniprot.org/uniprot/H8MNH3 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS30940 ^@ http://purl.uniprot.org/uniprot/H8MNR0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04570 ^@ http://purl.uniprot.org/uniprot/H8MK80 ^@ Function|||Similarity|||Subunit ^@ Belongs to the SbcD family.|||Heterodimer of SbcC and SbcD.|||SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity. http://togogenome.org/gene/1144275:COCOR_RS30420 ^@ http://purl.uniprot.org/uniprot/H8ML55 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsZ family.|||Cytoplasm|||Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.|||Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins. http://togogenome.org/gene/1144275:COCOR_RS21970 ^@ http://purl.uniprot.org/uniprot/H8N210 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1144275:COCOR_RS34800 ^@ http://purl.uniprot.org/uniprot/H8N2H2 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/1144275:COCOR_RS24135 ^@ http://purl.uniprot.org/uniprot/H8MM52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.|||Catalyzes the oxidation of L-aspartate to iminoaspartate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30435 ^@ http://purl.uniprot.org/uniprot/H8ML57 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1144275:COCOR_RS32250 ^@ http://purl.uniprot.org/uniprot/H8MT07 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS19865 ^@ http://purl.uniprot.org/uniprot/H8MU59 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS30460 ^@ http://purl.uniprot.org/uniprot/H8ML62 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family. MurG subfamily.|||Cell inner membrane|||Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS19425 ^@ http://purl.uniprot.org/uniprot/H8MSJ9 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1144275:COCOR_RS24670 ^@ http://purl.uniprot.org/uniprot/H8MNL4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1144275:COCOR_RS18680 ^@ http://purl.uniprot.org/uniprot/H8MPR9 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1144275:COCOR_RS26115 ^@ http://purl.uniprot.org/uniprot/H8MUA7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11735 ^@ http://purl.uniprot.org/uniprot/H8MN55 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CpoB family.|||Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS16925 ^@ http://purl.uniprot.org/uniprot/H8MJ74 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS23260 ^@ http://purl.uniprot.org/uniprot/H8MJC8 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1144275:COCOR_RS05460 ^@ http://purl.uniprot.org/uniprot/H8MP57 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12630 ^@ http://purl.uniprot.org/uniprot/H8MQY3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1144275:COCOR_RS22490 ^@ http://purl.uniprot.org/uniprot/H8MGM5 ^@ Function|||Similarity ^@ Belongs to the LDH/MDH superfamily. MDH type 3 family.|||Catalyzes the reversible oxidation of malate to oxaloacetate. http://togogenome.org/gene/1144275:COCOR_RS26495 ^@ http://purl.uniprot.org/uniprot/H8MVW2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 20 kDa subunit family.|||Binds 1 [4Fe-4S] cluster.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS18665 ^@ http://purl.uniprot.org/uniprot/H8MPR6 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the LipB family.|||Belongs to the Nudix hydrolase family.|||Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.|||Cytoplasm|||In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes. http://togogenome.org/gene/1144275:COCOR_RS16095 ^@ http://purl.uniprot.org/uniprot/H8MGG0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS34775 ^@ http://purl.uniprot.org/uniprot/H8N2G7 ^@ Similarity ^@ Belongs to the GST superfamily. Zeta family. http://togogenome.org/gene/1144275:COCOR_RS20560 ^@ http://purl.uniprot.org/uniprot/H8MXA2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS32940 ^@ http://purl.uniprot.org/uniprot/H8MW49 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1144275:COCOR_RS33755 ^@ http://purl.uniprot.org/uniprot/H8MZC2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS22600 ^@ http://purl.uniprot.org/uniprot/H8MGP7 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1144275:COCOR_RS18630 ^@ http://purl.uniprot.org/uniprot/H8MPQ9 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1144275:COCOR_RS17555 ^@ http://purl.uniprot.org/uniprot/H8MKP5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS31825 ^@ http://purl.uniprot.org/uniprot/H8MRI8 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1144275:COCOR_RS00530 ^@ http://purl.uniprot.org/uniprot/H8MTK1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS06520 ^@ http://purl.uniprot.org/uniprot/H8MS52 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Cytoplasm|||Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. http://togogenome.org/gene/1144275:COCOR_RS16860 ^@ http://purl.uniprot.org/uniprot/H8MJ62 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS19295 ^@ http://purl.uniprot.org/uniprot/H8MSH3 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1144275:COCOR_RS05585 ^@ http://purl.uniprot.org/uniprot/H8MP82 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1144275:COCOR_RS15110 ^@ http://purl.uniprot.org/uniprot/H8N0F0 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS35035 ^@ http://purl.uniprot.org/uniprot/H8MFT7 ^@ Similarity ^@ Belongs to the Nth/MutY family. http://togogenome.org/gene/1144275:COCOR_RS31685 ^@ http://purl.uniprot.org/uniprot/H8MRG0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M3 family.|||Binds 1 zinc ion. http://togogenome.org/gene/1144275:COCOR_RS37340 ^@ http://purl.uniprot.org/uniprot/H8MNZ7 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS25135 ^@ http://purl.uniprot.org/uniprot/H8MQ02 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS25630 ^@ http://purl.uniprot.org/uniprot/H8MRF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BI1 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS15640 ^@ http://purl.uniprot.org/uniprot/H8MF29 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS07620 ^@ http://purl.uniprot.org/uniprot/H8MWU7 ^@ Function|||Similarity ^@ Belongs to the PurU family.|||Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). http://togogenome.org/gene/1144275:COCOR_RS01345 ^@ http://purl.uniprot.org/uniprot/H8MWQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Belongs to the TonB-dependent receptor family.|||Cell inner membrane|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS18985 ^@ http://purl.uniprot.org/uniprot/H8MR26 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1144275:COCOR_RS37030 ^@ http://purl.uniprot.org/uniprot/H8MMN3 ^@ Similarity ^@ Belongs to the DNase I family. http://togogenome.org/gene/1144275:COCOR_RS23010 ^@ http://purl.uniprot.org/uniprot/H8MI26 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1144275:COCOR_RS03410 ^@ http://purl.uniprot.org/uniprot/H8MG50 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS14810 ^@ http://purl.uniprot.org/uniprot/H8N090 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS29750 ^@ http://purl.uniprot.org/uniprot/H8MJM1 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS06665 ^@ http://purl.uniprot.org/uniprot/H8MTK6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1144275:COCOR_RS08190 ^@ http://purl.uniprot.org/uniprot/H8MYJ7 ^@ Similarity ^@ Belongs to the UPF0178 family. http://togogenome.org/gene/1144275:COCOR_RS38140 ^@ http://purl.uniprot.org/uniprot/H8MRQ5 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS26715 ^@ http://purl.uniprot.org/uniprot/H8MW06 ^@ Function ^@ Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. http://togogenome.org/gene/1144275:COCOR_RS17295 ^@ http://purl.uniprot.org/uniprot/H8MKJ7 ^@ Subcellular Location Annotation ^@ Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS30135 ^@ http://purl.uniprot.org/uniprot/H8ML01 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1144275:COCOR_RS39395 ^@ http://purl.uniprot.org/uniprot/H8MWE6 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS09125 ^@ http://purl.uniprot.org/uniprot/H8MET9 ^@ Similarity ^@ Belongs to the deoxyhypusine synthase family. http://togogenome.org/gene/1144275:COCOR_RS11765 ^@ http://purl.uniprot.org/uniprot/H8MN62 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS20475 ^@ http://purl.uniprot.org/uniprot/H8MX85 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.|||Cell inner membrane|||Membrane|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1144275:COCOR_RS07915 ^@ http://purl.uniprot.org/uniprot/H8MYE0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS28690 ^@ http://purl.uniprot.org/uniprot/H8MFL9 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1144275:COCOR_RS35245 ^@ http://purl.uniprot.org/uniprot/H8MH26 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS31195 ^@ http://purl.uniprot.org/uniprot/H8MNW2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the fatty acid desaturase CarF family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08365 ^@ http://purl.uniprot.org/uniprot/H8N013 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS15310 ^@ http://purl.uniprot.org/uniprot/H8N1P5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1144275:COCOR_RS00820 ^@ http://purl.uniprot.org/uniprot/H8MV29 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13690 ^@ http://purl.uniprot.org/uniprot/H8MVH9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29410 ^@ http://purl.uniprot.org/uniprot/H8MI99 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1144275:COCOR_RS07040 ^@ http://purl.uniprot.org/uniprot/H8MTT2 ^@ Similarity ^@ Belongs to the PTPS family. QueD subfamily. http://togogenome.org/gene/1144275:COCOR_RS38780 ^@ http://purl.uniprot.org/uniprot/H8MTB7 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1144275:COCOR_RS27905 ^@ http://purl.uniprot.org/uniprot/H8N0T7 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS13125 ^@ http://purl.uniprot.org/uniprot/H8MTT9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS27095 ^@ http://purl.uniprot.org/uniprot/H8MXK6 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1144275:COCOR_RS05835 ^@ http://purl.uniprot.org/uniprot/H8MPD3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the radical SAM superfamily. Biotin synthase family.|||Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS31690 ^@ http://purl.uniprot.org/uniprot/H8MRG1 ^@ Similarity ^@ Belongs to the intimin/invasin family. http://togogenome.org/gene/1144275:COCOR_RS25950 ^@ http://purl.uniprot.org/uniprot/H8MSV1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS00355 ^@ http://purl.uniprot.org/uniprot/H8MTG5 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS30485 ^@ http://purl.uniprot.org/uniprot/H8MMB7 ^@ Caution|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurE subfamily.|||Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.|||Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS13285 ^@ http://purl.uniprot.org/uniprot/H8MTX1 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS21395 ^@ http://purl.uniprot.org/uniprot/H8N0I4 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).|||Cell membrane|||Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.|||Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase. http://togogenome.org/gene/1144275:COCOR_RS28480 ^@ http://purl.uniprot.org/uniprot/H8MFH8 ^@ Similarity ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. http://togogenome.org/gene/1144275:COCOR_RS31955 ^@ http://purl.uniprot.org/uniprot/H8MRL4 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1144275:COCOR_RS01565 ^@ http://purl.uniprot.org/uniprot/H8MY79 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS27160 ^@ http://purl.uniprot.org/uniprot/H8MXL9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC transporter superfamily. UvrA family.|||Cytoplasm|||Forms a heterotetramer with UvrB during the search for lesions.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. http://togogenome.org/gene/1144275:COCOR_RS11710 ^@ http://purl.uniprot.org/uniprot/H8MN50 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS10040 ^@ http://purl.uniprot.org/uniprot/H8MHM2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the BamD family.|||Cell outer membrane|||Part of the Bam complex.|||Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. http://togogenome.org/gene/1144275:COCOR_RS26885 ^@ http://purl.uniprot.org/uniprot/H8MXG5 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS24025 ^@ http://purl.uniprot.org/uniprot/H8MKY1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS12390 ^@ http://purl.uniprot.org/uniprot/H8MQT6 ^@ Function|||Similarity ^@ Belongs to the LpxC family.|||Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS10130 ^@ http://purl.uniprot.org/uniprot/H8MHN4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.|||Cytoplasm|||Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase. http://togogenome.org/gene/1144275:COCOR_RS19975 ^@ http://purl.uniprot.org/uniprot/H8MU81 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/1144275:COCOR_RS03785 ^@ http://purl.uniprot.org/uniprot/H8MHH5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS01220 ^@ http://purl.uniprot.org/uniprot/H8MWN0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS00430 ^@ http://purl.uniprot.org/uniprot/H8MTI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10575 ^@ http://purl.uniprot.org/uniprot/H8MJ22 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS32035 ^@ http://purl.uniprot.org/uniprot/H8MRM9 ^@ Similarity ^@ Belongs to the GST superfamily. NadH family. http://togogenome.org/gene/1144275:COCOR_RS05730 ^@ http://purl.uniprot.org/uniprot/H8MPB2 ^@ Cofactor|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family.|||Binds 1 divalent metal cation per subunit. http://togogenome.org/gene/1144275:COCOR_RS14645 ^@ http://purl.uniprot.org/uniprot/H8MYS5 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family. GreB subfamily.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length. http://togogenome.org/gene/1144275:COCOR_RS26105 ^@ http://purl.uniprot.org/uniprot/H8MUA5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS13860 ^@ http://purl.uniprot.org/uniprot/H8MVL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS06525 ^@ http://purl.uniprot.org/uniprot/H8MS53 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS24920 ^@ http://purl.uniprot.org/uniprot/H8MPW1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS41405 ^@ http://purl.uniprot.org/uniprot/H8MY33 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03290 ^@ http://purl.uniprot.org/uniprot/H8MG28 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1144275:COCOR_RS37895 ^@ http://purl.uniprot.org/uniprot/H8MQF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS16195 ^@ http://purl.uniprot.org/uniprot/H8MGI1 ^@ Similarity ^@ Belongs to the aspartate/glutamate racemases family. http://togogenome.org/gene/1144275:COCOR_RS12220 ^@ http://purl.uniprot.org/uniprot/H8MPK5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29300 ^@ http://purl.uniprot.org/uniprot/H8MI79 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1144275:COCOR_RS36955 ^@ http://purl.uniprot.org/uniprot/H8MML8 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS37195 ^@ http://purl.uniprot.org/uniprot/H8MMR6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.|||Cell inner membrane|||Involved in the import of queuosine (Q) precursors, required for Q precursor salvage. http://togogenome.org/gene/1144275:COCOR_RS30630 ^@ http://purl.uniprot.org/uniprot/H8MME6 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS32390 ^@ http://purl.uniprot.org/uniprot/H8MT35 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.|||Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Homohexamer. Dimer of a homotrimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Purine nucleoside phosphorylase involved in purine salvage. http://togogenome.org/gene/1144275:COCOR_RS33305 ^@ http://purl.uniprot.org/uniprot/H8MXP9 ^@ Function ^@ Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). http://togogenome.org/gene/1144275:COCOR_RS01610 ^@ http://purl.uniprot.org/uniprot/H8MY88 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS12440 ^@ http://purl.uniprot.org/uniprot/H8MQU6 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1144275:COCOR_RS28000 ^@ http://purl.uniprot.org/uniprot/H8N0V6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS07940 ^@ http://purl.uniprot.org/uniprot/H8MYE5 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1144275:COCOR_RS36475 ^@ http://purl.uniprot.org/uniprot/H8ML72 ^@ Function|||Similarity ^@ Belongs to the HrcA family.|||Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons. http://togogenome.org/gene/1144275:COCOR_RS21405 ^@ http://purl.uniprot.org/uniprot/H8N0I6 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1144275:COCOR_RS01255 ^@ http://purl.uniprot.org/uniprot/H8MWN7 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS32000 ^@ http://purl.uniprot.org/uniprot/H8MRM2 ^@ Similarity|||Subunit ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.|||Heterodimer of a large and a small subunit. http://togogenome.org/gene/1144275:COCOR_RS03360 ^@ http://purl.uniprot.org/uniprot/H8MG41 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS18580 ^@ http://purl.uniprot.org/uniprot/H8MPP9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the HisA/HisF family.|||Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. http://togogenome.org/gene/1144275:COCOR_RS37390 ^@ http://purl.uniprot.org/uniprot/H8MP07 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS33770 ^@ http://purl.uniprot.org/uniprot/H8MZC5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04625 ^@ http://purl.uniprot.org/uniprot/H8MK91 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS25230 ^@ http://purl.uniprot.org/uniprot/H8MQ21 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS10440 ^@ http://purl.uniprot.org/uniprot/H8MIZ6 ^@ Similarity ^@ Belongs to the ArsC family. http://togogenome.org/gene/1144275:COCOR_RS13195 ^@ http://purl.uniprot.org/uniprot/H8MTV3 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1144275:COCOR_RS30055 ^@ http://purl.uniprot.org/uniprot/H8MKY5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the polyribonucleotide nucleotidyltransferase family.|||Cytoplasm|||Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction. http://togogenome.org/gene/1144275:COCOR_RS22245 ^@ http://purl.uniprot.org/uniprot/H8MFD2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS36645 ^@ http://purl.uniprot.org/uniprot/H8MLA6 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS30440 ^@ http://purl.uniprot.org/uniprot/H8ML58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsQ/DivIB family. FtsQ subfamily.|||Cell inner membrane|||Essential cell division protein. http://togogenome.org/gene/1144275:COCOR_RS05740 ^@ http://purl.uniprot.org/uniprot/H8MPB4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS00620 ^@ http://purl.uniprot.org/uniprot/H8MUZ1 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS33760 ^@ http://purl.uniprot.org/uniprot/H8MZC3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS08210 ^@ http://purl.uniprot.org/uniprot/H8MYK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS00900 ^@ http://purl.uniprot.org/uniprot/H8MV45 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS30085 ^@ http://purl.uniprot.org/uniprot/H8MKZ1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. http://togogenome.org/gene/1144275:COCOR_RS13120 ^@ http://purl.uniprot.org/uniprot/H8MTT8 ^@ Similarity ^@ Belongs to the LacAB/RpiB family. http://togogenome.org/gene/1144275:COCOR_RS41120 ^@ http://purl.uniprot.org/uniprot/H8MGY6 ^@ Caution|||Cofactor ^@ Binds 1 zinc ion per subunit.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS10680 ^@ http://purl.uniprot.org/uniprot/H8MK95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03570 ^@ http://purl.uniprot.org/uniprot/H8MHD2 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1144275:COCOR_RS32255 ^@ http://purl.uniprot.org/uniprot/H8MT08 ^@ Similarity ^@ Belongs to the OMP decarboxylase family. Type 2 subfamily. http://togogenome.org/gene/1144275:COCOR_RS27675 ^@ http://purl.uniprot.org/uniprot/H8N0N9 ^@ Function|||Similarity ^@ Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.|||Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1144275:COCOR_RS21860 ^@ http://purl.uniprot.org/uniprot/H8N1Y8 ^@ Cofactor ^@ Binds 1 phosphopantetheine covalently. http://togogenome.org/gene/1144275:COCOR_RS30610 ^@ http://purl.uniprot.org/uniprot/H8MME2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS18570 ^@ http://purl.uniprot.org/uniprot/H8MPP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS32515 ^@ http://purl.uniprot.org/uniprot/H8MUI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS40340 ^@ http://purl.uniprot.org/uniprot/H8MZP4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MnmG family.|||Cytoplasm|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. http://togogenome.org/gene/1144275:COCOR_RS34735 ^@ http://purl.uniprot.org/uniprot/H8N2F9 ^@ Similarity ^@ Belongs to the SUI1 family. http://togogenome.org/gene/1144275:COCOR_RS04470 ^@ http://purl.uniprot.org/uniprot/H8MK59 ^@ Similarity ^@ In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1144275:COCOR_RS33330 ^@ http://purl.uniprot.org/uniprot/H8MXQ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS12955 ^@ http://purl.uniprot.org/uniprot/H8MSC9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MscS (TC 1.A.23) family.|||Cell inner membrane|||Homoheptamer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS07850 ^@ http://purl.uniprot.org/uniprot/H8MWZ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS17545 ^@ http://purl.uniprot.org/uniprot/H8MKP3 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS32895 ^@ http://purl.uniprot.org/uniprot/H8MW40 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1144275:COCOR_RS24200 ^@ http://purl.uniprot.org/uniprot/H8MM65 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1144275:COCOR_RS23420 ^@ http://purl.uniprot.org/uniprot/H8MJG2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.|||Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS33040 ^@ http://purl.uniprot.org/uniprot/H8MW69 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08230 ^@ http://purl.uniprot.org/uniprot/H8MYK5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS05000 ^@ http://purl.uniprot.org/uniprot/H8MLL6 ^@ Function|||Similarity ^@ Belongs to the sigma-54 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1144275:COCOR_RS21065 ^@ http://purl.uniprot.org/uniprot/H8MYY5 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS38500 ^@ http://purl.uniprot.org/uniprot/H8MT63 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS23405 ^@ http://purl.uniprot.org/uniprot/H8MJF9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DHBP synthase family.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Homodimer.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1144275:COCOR_RS38015 ^@ http://purl.uniprot.org/uniprot/H8MQH8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS32235 ^@ http://purl.uniprot.org/uniprot/H8MT04 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1144275:COCOR_RS04055 ^@ http://purl.uniprot.org/uniprot/H8MIS3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS39605 ^@ http://purl.uniprot.org/uniprot/H8MWI1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1144275:COCOR_RS31425 ^@ http://purl.uniprot.org/uniprot/H8MQ56 ^@ Function|||Similarity ^@ Belongs to the ribF family.|||Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. http://togogenome.org/gene/1144275:COCOR_RS20605 ^@ http://purl.uniprot.org/uniprot/H8MXB1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1144275:COCOR_RS24740 ^@ http://purl.uniprot.org/uniprot/H8MNM8 ^@ Function|||Similarity ^@ Belongs to the RecO family.|||Involved in DNA repair and RecF pathway recombination. http://togogenome.org/gene/1144275:COCOR_RS28650 ^@ http://purl.uniprot.org/uniprot/H8MFL1 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase S45 family.|||Binds 1 Ca(2+) ion per dimer. http://togogenome.org/gene/1144275:COCOR_RS14970 ^@ http://purl.uniprot.org/uniprot/H8N0C2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmB/CycW/HelB family.|||Cell inner membrane|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1144275:COCOR_RS07875 ^@ http://purl.uniprot.org/uniprot/H8MYD2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS10810 ^@ http://purl.uniprot.org/uniprot/H8MKC0 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS30465 ^@ http://purl.uniprot.org/uniprot/H8MMB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS03680 ^@ http://purl.uniprot.org/uniprot/H8MHF4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Belongs to the TonB-dependent receptor family.|||Cell inner membrane|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS10550 ^@ http://purl.uniprot.org/uniprot/H8MJ17 ^@ Similarity ^@ Belongs to the beta-class carbonic anhydrase family. http://togogenome.org/gene/1144275:COCOR_RS39690 ^@ http://purl.uniprot.org/uniprot/H8MXY0 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS03720 ^@ http://purl.uniprot.org/uniprot/H8MHG2 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS18690 ^@ http://purl.uniprot.org/uniprot/H8MPS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS28755 ^@ http://purl.uniprot.org/uniprot/H8MFN1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TVP38/TMEM64 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS34740 ^@ http://purl.uniprot.org/uniprot/H8N2G0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the VKOR family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS02470 ^@ http://purl.uniprot.org/uniprot/H8N197 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.|||Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).|||The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.|||The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1. http://togogenome.org/gene/1144275:COCOR_RS08805 ^@ http://purl.uniprot.org/uniprot/H8N1F7 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS26490 ^@ http://purl.uniprot.org/uniprot/H8MVW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 3 family.|||Cell inner membrane|||Cell membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS30890 ^@ http://purl.uniprot.org/uniprot/H8MNQ0 ^@ Similarity ^@ Belongs to the PspA/IM30 family. http://togogenome.org/gene/1144275:COCOR_RS28855 ^@ http://purl.uniprot.org/uniprot/H8MGU9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04935 ^@ http://purl.uniprot.org/uniprot/H8MLK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS19730 ^@ http://purl.uniprot.org/uniprot/H8MU32 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1144275:COCOR_RS29535 ^@ http://purl.uniprot.org/uniprot/H8MIC4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11090 ^@ http://purl.uniprot.org/uniprot/H8MLM9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1144275:COCOR_RS40095 ^@ http://purl.uniprot.org/uniprot/H8MZJ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS31470 ^@ http://purl.uniprot.org/uniprot/H8MQ65 ^@ Cofactor ^@ Binds 1 Ca(2+) ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS24545 ^@ http://purl.uniprot.org/uniprot/H8MNI8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RdgC family.|||May be involved in recombination.|||nucleoid http://togogenome.org/gene/1144275:COCOR_RS23850 ^@ http://purl.uniprot.org/uniprot/H8MKU6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1144275:COCOR_RS33625 ^@ http://purl.uniprot.org/uniprot/H8MXW4 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate. http://togogenome.org/gene/1144275:COCOR_RS27805 ^@ http://purl.uniprot.org/uniprot/H8N0R6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1144275:COCOR_RS14745 ^@ http://purl.uniprot.org/uniprot/H8N077 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1144275:COCOR_RS21840 ^@ http://purl.uniprot.org/uniprot/H8N1Y4 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS19545 ^@ http://purl.uniprot.org/uniprot/H8MSM3 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1144275:COCOR_RS21645 ^@ http://purl.uniprot.org/uniprot/H8N1U4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.|||Homodimer.|||Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1->4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB. http://togogenome.org/gene/1144275:COCOR_RS08395 ^@ http://purl.uniprot.org/uniprot/H8N019 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS25725 ^@ http://purl.uniprot.org/uniprot/H8MSQ5 ^@ Similarity ^@ Belongs to the XFP family. http://togogenome.org/gene/1144275:COCOR_RS09060 ^@ http://purl.uniprot.org/uniprot/H8MES7 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS27550 ^@ http://purl.uniprot.org/uniprot/H8MZ82 ^@ Similarity ^@ Belongs to the peptidase C69 family. http://togogenome.org/gene/1144275:COCOR_RS02645 ^@ http://purl.uniprot.org/uniprot/H8MEJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS16240 ^@ http://purl.uniprot.org/uniprot/H8MGJ0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1144275:COCOR_RS13640 ^@ http://purl.uniprot.org/uniprot/H8MVG9 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS24780 ^@ http://purl.uniprot.org/uniprot/H8MNN6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS20005 ^@ http://purl.uniprot.org/uniprot/H8MU87 ^@ Similarity ^@ Belongs to the pseudouridine synthase TruD family. http://togogenome.org/gene/1144275:COCOR_RS21210 ^@ http://purl.uniprot.org/uniprot/H8MZ16 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS27285 ^@ http://purl.uniprot.org/uniprot/H8MZ26 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1144275:COCOR_RS29695 ^@ http://purl.uniprot.org/uniprot/H8MJL0 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS17330 ^@ http://purl.uniprot.org/uniprot/H8MKK4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC41A transporter family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30070 ^@ http://purl.uniprot.org/uniprot/H8MKY8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1144275:COCOR_RS22415 ^@ http://purl.uniprot.org/uniprot/H8MFG4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmI family.|||Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS31530 ^@ http://purl.uniprot.org/uniprot/H8MQ79 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS10720 ^@ http://purl.uniprot.org/uniprot/H8MKA3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS15415 ^@ http://purl.uniprot.org/uniprot/H8N1R5 ^@ Subcellular Location Annotation ^@ Nucleus http://togogenome.org/gene/1144275:COCOR_RS10615 ^@ http://purl.uniprot.org/uniprot/H8MJ30 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1144275:COCOR_RS15585 ^@ http://purl.uniprot.org/uniprot/H8MF18 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS17725 ^@ http://purl.uniprot.org/uniprot/H8MLY1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1144275:COCOR_RS30165 ^@ http://purl.uniprot.org/uniprot/H8ML07 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1144275:COCOR_RS14940 ^@ http://purl.uniprot.org/uniprot/H8N0B5 ^@ Function|||Similarity ^@ Belongs to the CcmH/CycL/Ccl2/NrfF family.|||Possible subunit of a heme lyase. http://togogenome.org/gene/1144275:COCOR_RS32215 ^@ http://purl.uniprot.org/uniprot/H8MT00 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS00625 ^@ http://purl.uniprot.org/uniprot/H8MUZ2 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS05465 ^@ http://purl.uniprot.org/uniprot/H8MP58 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA methyltransferase RsmE family.|||Cytoplasm|||Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS13485 ^@ http://purl.uniprot.org/uniprot/H8MU07 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1144275:COCOR_RS10325 ^@ http://purl.uniprot.org/uniprot/H8MIX3 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS00720 ^@ http://purl.uniprot.org/uniprot/H8MV09 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1144275:COCOR_RS24965 ^@ http://purl.uniprot.org/uniprot/H8MPW9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the GcvH family.|||Binds 1 lipoyl cofactor covalently.|||The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1144275:COCOR_RS22015 ^@ http://purl.uniprot.org/uniprot/H8MF89 ^@ Similarity ^@ Belongs to the peptidase S1B family. http://togogenome.org/gene/1144275:COCOR_RS06700 ^@ http://purl.uniprot.org/uniprot/H8MTL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS24975 ^@ http://purl.uniprot.org/uniprot/H8MPX1 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1144275:COCOR_RS20990 ^@ http://purl.uniprot.org/uniprot/H8MYX0 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS17885 ^@ http://purl.uniprot.org/uniprot/H8MM12 ^@ Similarity ^@ Belongs to the ferredoxin--NADP reductase type 1 family. http://togogenome.org/gene/1144275:COCOR_RS13365 ^@ http://purl.uniprot.org/uniprot/H8MTY7 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS07290 ^@ http://purl.uniprot.org/uniprot/H8MVA9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNase H family.|||Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.|||Cytoplasm|||Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS15205 ^@ http://purl.uniprot.org/uniprot/H8N1M5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1144275:COCOR_RS00825 ^@ http://purl.uniprot.org/uniprot/H8MV30 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS25360 ^@ http://purl.uniprot.org/uniprot/H8MR99 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS43840 ^@ http://purl.uniprot.org/uniprot/H8MXL0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS23965 ^@ http://purl.uniprot.org/uniprot/H8MKW8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS41485 ^@ http://purl.uniprot.org/uniprot/H8MQS5 ^@ Similarity|||Subunit ^@ Belongs to the FPG family.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS21650 ^@ http://purl.uniprot.org/uniprot/H8N1U5 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. TreS subfamily. http://togogenome.org/gene/1144275:COCOR_RS26250 ^@ http://purl.uniprot.org/uniprot/H8MUD2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. http://togogenome.org/gene/1144275:COCOR_RS10180 ^@ http://purl.uniprot.org/uniprot/H8MHP4 ^@ Similarity ^@ Belongs to the BolA/IbaG family. http://togogenome.org/gene/1144275:COCOR_RS32025 ^@ http://purl.uniprot.org/uniprot/H8MRM7 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS18590 ^@ http://purl.uniprot.org/uniprot/H8MPQ1 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1144275:COCOR_RS08030 ^@ http://purl.uniprot.org/uniprot/H8MYG4 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS23840 ^@ http://purl.uniprot.org/uniprot/H8MKU4 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS24310 ^@ http://purl.uniprot.org/uniprot/H8MM87 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS33875 ^@ http://purl.uniprot.org/uniprot/H8MZE6 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 43 family. http://togogenome.org/gene/1144275:COCOR_RS39240 ^@ http://purl.uniprot.org/uniprot/H8MWB3 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS23350 ^@ http://purl.uniprot.org/uniprot/H8MJE8 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS06230 ^@ http://purl.uniprot.org/uniprot/H8MQQ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS11530 ^@ http://purl.uniprot.org/uniprot/H8MN14 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruD family.|||Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs. http://togogenome.org/gene/1144275:COCOR_RS06890 ^@ http://purl.uniprot.org/uniprot/H8MTQ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS27660 ^@ http://purl.uniprot.org/uniprot/H8N0N6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS13535 ^@ http://purl.uniprot.org/uniprot/H8MVE8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS39930 ^@ http://purl.uniprot.org/uniprot/H8MY30 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1144275:COCOR_RS18585 ^@ http://purl.uniprot.org/uniprot/H8MPQ0 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1144275:COCOR_RS31420 ^@ http://purl.uniprot.org/uniprot/H8MQ55 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP E family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS16150 ^@ http://purl.uniprot.org/uniprot/H8MGH2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1144275:COCOR_RS17500 ^@ http://purl.uniprot.org/uniprot/H8MKN4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS21115 ^@ http://purl.uniprot.org/uniprot/H8MYZ4 ^@ Similarity ^@ Belongs to the peptidase S26 family. http://togogenome.org/gene/1144275:COCOR_RS34970 ^@ http://purl.uniprot.org/uniprot/H8MFS4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the aldolase class II family. MtnB subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). http://togogenome.org/gene/1144275:COCOR_RS37960 ^@ http://purl.uniprot.org/uniprot/H8MQG7 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1144275:COCOR_RS01440 ^@ http://purl.uniprot.org/uniprot/H8MY54 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS21595 ^@ http://purl.uniprot.org/uniprot/H8N0M6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS17795 ^@ http://purl.uniprot.org/uniprot/H8MLZ5 ^@ Similarity ^@ Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS10450 ^@ http://purl.uniprot.org/uniprot/H8MIZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS14965 ^@ http://purl.uniprot.org/uniprot/H8N0C1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CcmC/CycZ/HelC family.|||Membrane|||Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes. http://togogenome.org/gene/1144275:COCOR_RS38995 ^@ http://purl.uniprot.org/uniprot/H8MUT3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS39995 ^@ http://purl.uniprot.org/uniprot/H8MY43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS16615 ^@ http://purl.uniprot.org/uniprot/H8MHW3 ^@ Similarity ^@ Belongs to the ketopantoate reductase family. http://togogenome.org/gene/1144275:COCOR_RS22480 ^@ http://purl.uniprot.org/uniprot/H8MGM3 ^@ Similarity ^@ Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. http://togogenome.org/gene/1144275:COCOR_RS26920 ^@ http://purl.uniprot.org/uniprot/H8MXH2 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the glutamyl-tRNA reductase family.|||Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).|||During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.|||Homodimer.|||Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization. http://togogenome.org/gene/1144275:COCOR_RS28230 ^@ http://purl.uniprot.org/uniprot/H8N261 ^@ Similarity ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. http://togogenome.org/gene/1144275:COCOR_RS20440 ^@ http://purl.uniprot.org/uniprot/H8MX78 ^@ Similarity ^@ Belongs to the FAD-binding monooxygenase family. http://togogenome.org/gene/1144275:COCOR_RS18650 ^@ http://purl.uniprot.org/uniprot/H8MPR3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. Lipoyl synthase family.|||Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS23410 ^@ http://purl.uniprot.org/uniprot/H8MJG0 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1144275:COCOR_RS25335 ^@ http://purl.uniprot.org/uniprot/H8MR94 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. http://togogenome.org/gene/1144275:COCOR_RS05555 ^@ http://purl.uniprot.org/uniprot/H8MP76 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. Ycf16 family. http://togogenome.org/gene/1144275:COCOR_RS29335 ^@ http://purl.uniprot.org/uniprot/H8MI86 ^@ Similarity ^@ Belongs to the peptidase M13 family. http://togogenome.org/gene/1144275:COCOR_RS24245 ^@ http://purl.uniprot.org/uniprot/H8MM74 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS18905 ^@ http://purl.uniprot.org/uniprot/H8MR10 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1144275:COCOR_RS06640 ^@ http://purl.uniprot.org/uniprot/H8MS76 ^@ Similarity ^@ Belongs to the UDPGP type 2 family. http://togogenome.org/gene/1144275:COCOR_RS39965 ^@ http://purl.uniprot.org/uniprot/H8MY37 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS17760 ^@ http://purl.uniprot.org/uniprot/H8MLY8 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Belongs to the NnrE/AIBP family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS27670 ^@ http://purl.uniprot.org/uniprot/H8N0N8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DNA polymerase type-Y family.|||Binds 2 magnesium ions per subunit.|||Cytoplasm|||Monomer.|||Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. http://togogenome.org/gene/1144275:COCOR_RS25375 ^@ http://purl.uniprot.org/uniprot/H8MRA2 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1144275:COCOR_RS26980 ^@ http://purl.uniprot.org/uniprot/H8MXI4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family. YhdE subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1144275:COCOR_RS36865 ^@ http://purl.uniprot.org/uniprot/H8MMK0 ^@ Similarity ^@ Belongs to the transferase hexapeptide repeat family. http://togogenome.org/gene/1144275:COCOR_RS27565 ^@ http://purl.uniprot.org/uniprot/H8MZ86 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS02785 ^@ http://purl.uniprot.org/uniprot/H8MEM6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TspO/BZRP family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13540 ^@ http://purl.uniprot.org/uniprot/H8MVE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OprB family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS19870 ^@ http://purl.uniprot.org/uniprot/H8MU60 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS17440 ^@ http://purl.uniprot.org/uniprot/H8MKM2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS36070 ^@ http://purl.uniprot.org/uniprot/H8MJT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TMEM86 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS15170 ^@ http://purl.uniprot.org/uniprot/H8N1L8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS18555 ^@ http://purl.uniprot.org/uniprot/H8MPP4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS35545 ^@ http://purl.uniprot.org/uniprot/H8MH86 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS28385 ^@ http://purl.uniprot.org/uniprot/H8N292 ^@ Similarity ^@ Belongs to the peptidase M18 family. http://togogenome.org/gene/1144275:COCOR_RS34990 ^@ http://purl.uniprot.org/uniprot/H8MFS8 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the QueC family.|||Binds 1 zinc ion per subunit.|||Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). http://togogenome.org/gene/1144275:COCOR_RS21085 ^@ http://purl.uniprot.org/uniprot/H8MYY9 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS32420 ^@ http://purl.uniprot.org/uniprot/H8MT41 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS35115 ^@ http://purl.uniprot.org/uniprot/H8MFV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS36795 ^@ http://purl.uniprot.org/uniprot/H8MLD6 ^@ Similarity ^@ Belongs to the pterin-4-alpha-carbinolamine dehydratase family. http://togogenome.org/gene/1144275:COCOR_RS27830 ^@ http://purl.uniprot.org/uniprot/H8N0S1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ ATPase component of the type II secretion system required for the energy-dependent secretion of extracellular factors such as proteases and toxins from the periplasm. Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.|||Belongs to the GSP E family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS10900 ^@ http://purl.uniprot.org/uniprot/H8MKD8 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1144275:COCOR_RS12420 ^@ http://purl.uniprot.org/uniprot/H8MQU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37335 ^@ http://purl.uniprot.org/uniprot/H8MNZ6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS05045 ^@ http://purl.uniprot.org/uniprot/H8MMS4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.|||An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.|||Belongs to the DTD family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS38100 ^@ http://purl.uniprot.org/uniprot/H8MRP7 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS32355 ^@ http://purl.uniprot.org/uniprot/H8MT28 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapA family.|||Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).|||Cytoplasm|||Homotetramer; dimer of dimers.|||Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB. http://togogenome.org/gene/1144275:COCOR_RS00280 ^@ http://purl.uniprot.org/uniprot/H8MTE9 ^@ Function|||PTM|||Similarity ^@ An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.|||Belongs to the polyphosphate kinase 1 (PPK1) family.|||Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). http://togogenome.org/gene/1144275:COCOR_RS11775 ^@ http://purl.uniprot.org/uniprot/H8MN64 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS22555 ^@ http://purl.uniprot.org/uniprot/H8MGN8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the TPP enzyme family. MenD subfamily.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS12065 ^@ http://purl.uniprot.org/uniprot/H8MPH4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family.|||Binds 2 iron ions per subunit.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1144275:COCOR_RS23120 ^@ http://purl.uniprot.org/uniprot/H8MI48 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1144275:COCOR_RS01910 ^@ http://purl.uniprot.org/uniprot/H8MZS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. http://togogenome.org/gene/1144275:COCOR_RS10150 ^@ http://purl.uniprot.org/uniprot/H8MHN8 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1144275:COCOR_RS25020 ^@ http://purl.uniprot.org/uniprot/H8MPY0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11165 ^@ http://purl.uniprot.org/uniprot/H8MLP4 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS32925 ^@ http://purl.uniprot.org/uniprot/H8MW46 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the anthranilate phosphoribosyltransferase family.|||Binds 2 magnesium ions per monomer.|||Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS16560 ^@ http://purl.uniprot.org/uniprot/H8MHV3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Belongs to the histone H1/H5 family. HCT subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Might have a role in establishing the nucleoid structure of elementary bodies.|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1144275:COCOR_RS32360 ^@ http://purl.uniprot.org/uniprot/H8MT29 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1144275:COCOR_RS12490 ^@ http://purl.uniprot.org/uniprot/H8MQV6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS31395 ^@ http://purl.uniprot.org/uniprot/H8MQ50 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS30200 ^@ http://purl.uniprot.org/uniprot/H8ML10 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. http://togogenome.org/gene/1144275:COCOR_RS30935 ^@ http://purl.uniprot.org/uniprot/H8MNQ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS05240 ^@ http://purl.uniprot.org/uniprot/H8MMW3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS11755 ^@ http://purl.uniprot.org/uniprot/H8MN60 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.|||Binds 1 zinc ion per subunit.|||Binds the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS29690 ^@ http://purl.uniprot.org/uniprot/H8MJK9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. Tam family.|||Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS19445 ^@ http://purl.uniprot.org/uniprot/H8MSK3 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1144275:COCOR_RS13395 ^@ http://purl.uniprot.org/uniprot/H8MTZ3 ^@ Function|||Similarity ^@ Belongs to the LpxK family.|||Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). http://togogenome.org/gene/1144275:COCOR_RS30140 ^@ http://purl.uniprot.org/uniprot/H8ML02 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1144275:COCOR_RS35585 ^@ http://purl.uniprot.org/uniprot/H8MH94 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS06705 ^@ http://purl.uniprot.org/uniprot/H8MTL4 ^@ Similarity ^@ Belongs to the CinA family. http://togogenome.org/gene/1144275:COCOR_RS28530 ^@ http://purl.uniprot.org/uniprot/H8MFI8 ^@ Cofactor|||Similarity ^@ Belongs to the MsrB Met sulfoxide reductase family.|||Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein. http://togogenome.org/gene/1144275:COCOR_RS14170 ^@ http://purl.uniprot.org/uniprot/H8MX48 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS08905 ^@ http://purl.uniprot.org/uniprot/H8N1H7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1144275:COCOR_RS26860 ^@ http://purl.uniprot.org/uniprot/H8MXG0 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). http://togogenome.org/gene/1144275:COCOR_RS31260 ^@ http://purl.uniprot.org/uniprot/H8MQ23 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS22540 ^@ http://purl.uniprot.org/uniprot/H8MGN5 ^@ Function|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily.|||Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB). http://togogenome.org/gene/1144275:COCOR_RS03475 ^@ http://purl.uniprot.org/uniprot/H8MHB3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11490 ^@ http://purl.uniprot.org/uniprot/H8MN06 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the DnaG primase family.|||Binds 1 zinc ion per monomer.|||Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.|||Monomer. Interacts with DnaB.|||RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. http://togogenome.org/gene/1144275:COCOR_RS07220 ^@ http://purl.uniprot.org/uniprot/H8MV95 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS39270 ^@ http://purl.uniprot.org/uniprot/H8MWB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpC family.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1144275:COCOR_RS06390 ^@ http://purl.uniprot.org/uniprot/H8MS25 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS36175 ^@ http://purl.uniprot.org/uniprot/H8MJW1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.|||Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).|||Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS12330 ^@ http://purl.uniprot.org/uniprot/H8MQS4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30495 ^@ http://purl.uniprot.org/uniprot/H8MMB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FtsL family.|||Cell inner membrane|||Essential cell division protein.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32380 ^@ http://purl.uniprot.org/uniprot/H8MT33 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M48 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS07650 ^@ http://purl.uniprot.org/uniprot/H8MWV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS05490 ^@ http://purl.uniprot.org/uniprot/H8MP63 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.|||Cytoplasm|||Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1144275:COCOR_RS22815 ^@ http://purl.uniprot.org/uniprot/H8MGU0 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS22130 ^@ http://purl.uniprot.org/uniprot/H8MFB3 ^@ Similarity|||Subunit ^@ Belongs to the DNA polymerase type-A family.|||Single-chain monomer with multiple functions. http://togogenome.org/gene/1144275:COCOR_RS06740 ^@ http://purl.uniprot.org/uniprot/H8MTM1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS37965 ^@ http://purl.uniprot.org/uniprot/H8MQG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10010 ^@ http://purl.uniprot.org/uniprot/H8MHL6 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1144275:COCOR_RS20980 ^@ http://purl.uniprot.org/uniprot/H8MYW8 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase subunit B family. http://togogenome.org/gene/1144275:COCOR_RS11655 ^@ http://purl.uniprot.org/uniprot/H8MN39 ^@ Similarity ^@ Belongs to the SOS response-associated peptidase family. http://togogenome.org/gene/1144275:COCOR_RS40970 ^@ http://purl.uniprot.org/uniprot/H8MI28 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS13145 ^@ http://purl.uniprot.org/uniprot/H8MTU3 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1144275:COCOR_RS37095 ^@ http://purl.uniprot.org/uniprot/H8MMP6 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS25040 ^@ http://purl.uniprot.org/uniprot/H8MPY4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS18550 ^@ http://purl.uniprot.org/uniprot/H8MPP3 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ATP phosphoribosyltransferase family. Long subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Feedback inhibited by histidine. http://togogenome.org/gene/1144275:COCOR_RS09460 ^@ http://purl.uniprot.org/uniprot/H8MF05 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS27685 ^@ http://purl.uniprot.org/uniprot/H8N0P1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1144275:COCOR_RS24130 ^@ http://purl.uniprot.org/uniprot/H8MM51 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1144275:COCOR_RS12020 ^@ http://purl.uniprot.org/uniprot/H8MPG5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PTH family.|||Cytoplasm|||Monomer.|||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. http://togogenome.org/gene/1144275:COCOR_RS03010 ^@ http://purl.uniprot.org/uniprot/H8MES2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS17765 ^@ http://purl.uniprot.org/uniprot/H8MLY9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30090 ^@ http://purl.uniprot.org/uniprot/H8MKZ2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1144275:COCOR_RS06825 ^@ http://purl.uniprot.org/uniprot/H8MTN8 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1144275:COCOR_RS05230 ^@ http://purl.uniprot.org/uniprot/H8MMW1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12245 ^@ http://purl.uniprot.org/uniprot/H8MPK9 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1144275:COCOR_RS40085 ^@ http://purl.uniprot.org/uniprot/H8MZJ3 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1144275:COCOR_RS07865 ^@ http://purl.uniprot.org/uniprot/H8MYD0 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1144275:COCOR_RS32875 ^@ http://purl.uniprot.org/uniprot/H8MW36 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrQ family.|||Binds 1 FMN per subunit.|||Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.|||Cell inner membrane|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain. http://togogenome.org/gene/1144275:COCOR_RS38520 ^@ http://purl.uniprot.org/uniprot/H8MT67 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29130 ^@ http://purl.uniprot.org/uniprot/H8MH01 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS35995 ^@ http://purl.uniprot.org/uniprot/H8MIM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29780 ^@ http://purl.uniprot.org/uniprot/H8MJM7 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS06490 ^@ http://purl.uniprot.org/uniprot/H8MS46 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1144275:COCOR_RS17565 ^@ http://purl.uniprot.org/uniprot/H8MKP7 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS05475 ^@ http://purl.uniprot.org/uniprot/H8MP60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. PrmA family.|||Cytoplasm|||Methylates ribosomal protein L11. http://togogenome.org/gene/1144275:COCOR_RS21460 ^@ http://purl.uniprot.org/uniprot/H8N0J7 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS30095 ^@ http://purl.uniprot.org/uniprot/H8MKZ3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RimP family.|||Cytoplasm|||Required for maturation of 30S ribosomal subunits. http://togogenome.org/gene/1144275:COCOR_RS37140 ^@ http://purl.uniprot.org/uniprot/H8MMQ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS18605 ^@ http://purl.uniprot.org/uniprot/H8MPQ4 ^@ Cofactor|||Miscellaneous|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||The active site is a redox-active disulfide bond. http://togogenome.org/gene/1144275:COCOR_RS05990 ^@ http://purl.uniprot.org/uniprot/H8MQL1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS25325 ^@ http://purl.uniprot.org/uniprot/H8MR92 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the AP endonuclease 2 family.|||Binds 3 Zn(2+) ions.|||Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic (AP) sites, generating a 3'-hydroxyl group and a 5'-terminal sugar phosphate. http://togogenome.org/gene/1144275:COCOR_RS26765 ^@ http://purl.uniprot.org/uniprot/H8MW16 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS27950 ^@ http://purl.uniprot.org/uniprot/H8N0U6 ^@ Similarity ^@ Belongs to the peptidase S49 family. http://togogenome.org/gene/1144275:COCOR_RS05870 ^@ http://purl.uniprot.org/uniprot/H8MQI7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS07495 ^@ http://purl.uniprot.org/uniprot/H8MWS2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endonuclease V family.|||Cytoplasm|||DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. http://togogenome.org/gene/1144275:COCOR_RS30520 ^@ http://purl.uniprot.org/uniprot/H8MMC4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS06900 ^@ http://purl.uniprot.org/uniprot/H8MTQ3 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1144275:COCOR_RS02925 ^@ http://purl.uniprot.org/uniprot/H8MEQ5 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS06865 ^@ http://purl.uniprot.org/uniprot/H8MTP6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1144275:COCOR_RS37175 ^@ http://purl.uniprot.org/uniprot/H8MMR2 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1144275:COCOR_RS08405 ^@ http://purl.uniprot.org/uniprot/H8N021 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS03225 ^@ http://purl.uniprot.org/uniprot/H8MG15 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1144275:COCOR_RS00975 ^@ http://purl.uniprot.org/uniprot/H8MV59 ^@ Similarity ^@ Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family. http://togogenome.org/gene/1144275:COCOR_RS10160 ^@ http://purl.uniprot.org/uniprot/H8MHP0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS21050 ^@ http://purl.uniprot.org/uniprot/H8MYY2 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS30845 ^@ http://purl.uniprot.org/uniprot/H8MMI9 ^@ Similarity ^@ Belongs to the YkuD family. http://togogenome.org/gene/1144275:COCOR_RS06475 ^@ http://purl.uniprot.org/uniprot/H8MS43 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1144275:COCOR_RS29230 ^@ http://purl.uniprot.org/uniprot/H8MH20 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS11025 ^@ http://purl.uniprot.org/uniprot/H8MKG4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1144275:COCOR_RS26520 ^@ http://purl.uniprot.org/uniprot/H8MVW7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 49 kDa subunit family.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS22165 ^@ http://purl.uniprot.org/uniprot/H8MFB7 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1144275:COCOR_RS39115 ^@ http://purl.uniprot.org/uniprot/H8MUV7 ^@ Similarity ^@ Belongs to the nitroreductase family. HadB/RutE subfamily. http://togogenome.org/gene/1144275:COCOR_RS16990 ^@ http://purl.uniprot.org/uniprot/H8MJ87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS23065 ^@ http://purl.uniprot.org/uniprot/H8MI37 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS21150 ^@ http://purl.uniprot.org/uniprot/H8MZ03 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS24155 ^@ http://purl.uniprot.org/uniprot/H8MM56 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS13240 ^@ http://purl.uniprot.org/uniprot/H8MTW2 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1144275:COCOR_RS15325 ^@ http://purl.uniprot.org/uniprot/H8N1P8 ^@ Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL17 family.|||Part of the 50S ribosomal subunit. Contacts protein L32. http://togogenome.org/gene/1144275:COCOR_RS36420 ^@ http://purl.uniprot.org/uniprot/H8MK10 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1144275:COCOR_RS23185 ^@ http://purl.uniprot.org/uniprot/H8MI61 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.|||Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS17270 ^@ http://purl.uniprot.org/uniprot/H8MKJ2 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS10215 ^@ http://purl.uniprot.org/uniprot/H8MHQ1 ^@ Cofactor|||PTM|||Subcellular Location Annotation ^@ Binds 2 heme groups per subunit.|||Binds 2 heme groups.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS12185 ^@ http://purl.uniprot.org/uniprot/H8MPJ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IPP isomerase type 2 family.|||Cytoplasm|||Homooctamer. Dimer of tetramers.|||Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). http://togogenome.org/gene/1144275:COCOR_RS44615 ^@ http://purl.uniprot.org/uniprot/H8MLV6 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1144275:COCOR_RS33655 ^@ http://purl.uniprot.org/uniprot/H8MZA2 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS12250 ^@ http://purl.uniprot.org/uniprot/H8MPL0 ^@ Function|||Similarity ^@ A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.|||Belongs to the NifU family. http://togogenome.org/gene/1144275:COCOR_RS32090 ^@ http://purl.uniprot.org/uniprot/H8MSX4 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1144275:COCOR_RS35360 ^@ http://purl.uniprot.org/uniprot/H8MH50 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1144275:COCOR_RS04035 ^@ http://purl.uniprot.org/uniprot/H8MIR9 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. http://togogenome.org/gene/1144275:COCOR_RS36190 ^@ http://purl.uniprot.org/uniprot/H8MJW4 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1144275:COCOR_RS04740 ^@ http://purl.uniprot.org/uniprot/H8MLG4 ^@ Similarity ^@ In the N-terminal section; belongs to the phytochrome family. http://togogenome.org/gene/1144275:COCOR_RS35780 ^@ http://purl.uniprot.org/uniprot/H8MIH7 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1144275:COCOR_RS05725 ^@ http://purl.uniprot.org/uniprot/H8MPB1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/1144275:COCOR_RS26635 ^@ http://purl.uniprot.org/uniprot/H8MVZ0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccD/PCCB family.|||Binds 1 zinc ion per subunit.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS19850 ^@ http://purl.uniprot.org/uniprot/H8MU56 ^@ Similarity ^@ Belongs to the ROK (NagC/XylR) family. http://togogenome.org/gene/1144275:COCOR_RS27665 ^@ http://purl.uniprot.org/uniprot/H8N0N7 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1144275:COCOR_RS12035 ^@ http://purl.uniprot.org/uniprot/H8MPG8 ^@ Function|||Similarity ^@ Belongs to the SpoVG family.|||Could be involved in septation. http://togogenome.org/gene/1144275:COCOR_RS23230 ^@ http://purl.uniprot.org/uniprot/H8MJC2 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1144275:COCOR_RS39940 ^@ http://purl.uniprot.org/uniprot/H8MY32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS06650 ^@ http://purl.uniprot.org/uniprot/H8MS78 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS40080 ^@ http://purl.uniprot.org/uniprot/H8MZJ2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MobA family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer.|||The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.|||Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. http://togogenome.org/gene/1144275:COCOR_RS29610 ^@ http://purl.uniprot.org/uniprot/H8MID9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.|||Mitochondrion http://togogenome.org/gene/1144275:COCOR_RS12280 ^@ http://purl.uniprot.org/uniprot/H8MQR4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS06735 ^@ http://purl.uniprot.org/uniprot/H8MTM0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS09985 ^@ http://purl.uniprot.org/uniprot/H8MHL1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the Maf family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. http://togogenome.org/gene/1144275:COCOR_RS24225 ^@ http://purl.uniprot.org/uniprot/H8MM70 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseA family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1144275:COCOR_RS31340 ^@ http://purl.uniprot.org/uniprot/H8MQ39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS20960 ^@ http://purl.uniprot.org/uniprot/H8MYW4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS07060 ^@ http://purl.uniprot.org/uniprot/H8MV63 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS28260 ^@ http://purl.uniprot.org/uniprot/H8N267 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.|||Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.|||Cytoplasm|||Mitochondrion http://togogenome.org/gene/1144275:COCOR_RS19395 ^@ http://purl.uniprot.org/uniprot/H8MSJ3 ^@ Function|||Similarity ^@ Belongs to the esterase D family.|||Serine hydrolase involved in the detoxification of formaldehyde. http://togogenome.org/gene/1144275:COCOR_RS05180 ^@ http://purl.uniprot.org/uniprot/H8MMV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS28015 ^@ http://purl.uniprot.org/uniprot/H8N0V9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS13360 ^@ http://purl.uniprot.org/uniprot/H8MTY6 ^@ Function|||Similarity ^@ Belongs to the LpxB family.|||Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1144275:COCOR_RS25245 ^@ http://purl.uniprot.org/uniprot/H8MR76 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1144275:COCOR_RS31210 ^@ http://purl.uniprot.org/uniprot/H8MNW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS28420 ^@ http://purl.uniprot.org/uniprot/H8N299 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 87 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS17995 ^@ http://purl.uniprot.org/uniprot/H8MN84 ^@ Similarity ^@ In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1144275:COCOR_RS12240 ^@ http://purl.uniprot.org/uniprot/H8MPK8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HscB family.|||Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.|||Interacts with HscA and stimulates its ATPase activity. http://togogenome.org/gene/1144275:COCOR_RS03790 ^@ http://purl.uniprot.org/uniprot/H8MHH6 ^@ Similarity ^@ Belongs to the Dps family. http://togogenome.org/gene/1144275:COCOR_RS20285 ^@ http://purl.uniprot.org/uniprot/H8MVS2 ^@ Similarity|||Subunit ^@ Belongs to the glutaminase family.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS15450 ^@ http://purl.uniprot.org/uniprot/H8N1S2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS12105 ^@ http://purl.uniprot.org/uniprot/H8MPI2 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS03925 ^@ http://purl.uniprot.org/uniprot/H8MIP7 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS30310 ^@ http://purl.uniprot.org/uniprot/H8ML33 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1144275:COCOR_RS25755 ^@ http://purl.uniprot.org/uniprot/H8MSR1 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1144275:COCOR_RS24440 ^@ http://purl.uniprot.org/uniprot/H8MNG5 ^@ Similarity ^@ Belongs to the PhzF family. http://togogenome.org/gene/1144275:COCOR_RS35575 ^@ http://purl.uniprot.org/uniprot/H8MH92 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS39955 ^@ http://purl.uniprot.org/uniprot/H8MY35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11000 ^@ http://purl.uniprot.org/uniprot/H8MKF9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAD kinase family.|||Cytoplasm|||Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS15245 ^@ http://purl.uniprot.org/uniprot/H8N1N3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1144275:COCOR_RS21655 ^@ http://purl.uniprot.org/uniprot/H8N1U6 ^@ Similarity ^@ Belongs to the aminoglycoside phosphotransferase family. http://togogenome.org/gene/1144275:COCOR_RS24790 ^@ http://purl.uniprot.org/uniprot/H8MNN8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1144275:COCOR_RS03915 ^@ http://purl.uniprot.org/uniprot/H8MIP5 ^@ Similarity ^@ Belongs to the carotenoid/retinoid oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS37550 ^@ http://purl.uniprot.org/uniprot/H8MP39 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS26095 ^@ http://purl.uniprot.org/uniprot/H8MUA3 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1144275:COCOR_RS18070 ^@ http://purl.uniprot.org/uniprot/H8MN99 ^@ Similarity ^@ To bacterial alkanal monooxygenase alpha and beta chains. http://togogenome.org/gene/1144275:COCOR_RS16660 ^@ http://purl.uniprot.org/uniprot/H8MHX2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS28695 ^@ http://purl.uniprot.org/uniprot/H8MFM0 ^@ Similarity ^@ Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. http://togogenome.org/gene/1144275:COCOR_RS18565 ^@ http://purl.uniprot.org/uniprot/H8MPP6 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1144275:COCOR_RS40160 ^@ http://purl.uniprot.org/uniprot/H8MZK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS16625 ^@ http://purl.uniprot.org/uniprot/H8MHW5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS30400 ^@ http://purl.uniprot.org/uniprot/H8ML51 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS21910 ^@ http://purl.uniprot.org/uniprot/H8N1Z8 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS05185 ^@ http://purl.uniprot.org/uniprot/H8MMV2 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS11600 ^@ http://purl.uniprot.org/uniprot/H8MN28 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1144275:COCOR_RS29285 ^@ http://purl.uniprot.org/uniprot/H8MI76 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1144275:COCOR_RS12665 ^@ http://purl.uniprot.org/uniprot/H8MQZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS26680 ^@ http://purl.uniprot.org/uniprot/H8MVZ9 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1144275:COCOR_RS18705 ^@ http://purl.uniprot.org/uniprot/H8MPS4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS29200 ^@ http://purl.uniprot.org/uniprot/H8MH14 ^@ Similarity ^@ Belongs to the DNA polymerase type-B family. http://togogenome.org/gene/1144275:COCOR_RS02710 ^@ http://purl.uniprot.org/uniprot/H8MEL2 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS12695 ^@ http://purl.uniprot.org/uniprot/H8MS81 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS17730 ^@ http://purl.uniprot.org/uniprot/H8MLY2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.|||Belongs to the AAA ATPase family.|||Binds 1 zinc ion per subunit.|||Cell inner membrane|||Homohexamer.|||In the C-terminal section; belongs to the peptidase M41 family.|||In the central section; belongs to the AAA ATPase family. http://togogenome.org/gene/1144275:COCOR_RS24690 ^@ http://purl.uniprot.org/uniprot/H8MNL8 ^@ Similarity ^@ Belongs to the peptidase A24 family. http://togogenome.org/gene/1144275:COCOR_RS15255 ^@ http://purl.uniprot.org/uniprot/H8N1N5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL6 family.|||Part of the 50S ribosomal subunit.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1144275:COCOR_RS26655 ^@ http://purl.uniprot.org/uniprot/H8MVZ4 ^@ Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. http://togogenome.org/gene/1144275:COCOR_RS04360 ^@ http://purl.uniprot.org/uniprot/H8MK37 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the 3-HAO family.|||Binds 2 Fe(2+) ions per subunit.|||Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS37005 ^@ http://purl.uniprot.org/uniprot/H8MMM8 ^@ Cofactor|||Function|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanD family.|||Binds 1 pyruvoyl group covalently per subunit.|||Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.|||Cytoplasm|||Heterooctamer of four alpha and four beta subunits.|||Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus. http://togogenome.org/gene/1144275:COCOR_RS32265 ^@ http://purl.uniprot.org/uniprot/H8MT10 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS25060 ^@ http://purl.uniprot.org/uniprot/H8MPY8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.|||Binds 1 FMN per subunit.|||Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.|||Cell membrane|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS24120 ^@ http://purl.uniprot.org/uniprot/H8MM49 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03185 ^@ http://purl.uniprot.org/uniprot/H8MG06 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1144275:COCOR_RS37465 ^@ http://purl.uniprot.org/uniprot/H8MP22 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1144275:COCOR_RS39280 ^@ http://purl.uniprot.org/uniprot/H8MWC1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the KdpA family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the periplasmic potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1144275:COCOR_RS24685 ^@ http://purl.uniprot.org/uniprot/H8MNL7 ^@ Similarity ^@ Belongs to the bacterial secretin family. http://togogenome.org/gene/1144275:COCOR_RS38485 ^@ http://purl.uniprot.org/uniprot/H8MT60 ^@ Similarity ^@ Belongs to the peptidase S9C family. http://togogenome.org/gene/1144275:COCOR_RS11620 ^@ http://purl.uniprot.org/uniprot/H8MN32 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 31 family. http://togogenome.org/gene/1144275:COCOR_RS15365 ^@ http://purl.uniprot.org/uniprot/H8N1Q6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/1144275:COCOR_RS40435 ^@ http://purl.uniprot.org/uniprot/H8N143 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RnpA family.|||Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.|||RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. http://togogenome.org/gene/1144275:COCOR_RS11220 ^@ http://purl.uniprot.org/uniprot/H8MLQ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12360 ^@ http://purl.uniprot.org/uniprot/H8MQT0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1144275:COCOR_RS05265 ^@ http://purl.uniprot.org/uniprot/H8MMW8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS01920 ^@ http://purl.uniprot.org/uniprot/H8MZT1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1144275:COCOR_RS11760 ^@ http://purl.uniprot.org/uniprot/H8MN61 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS15315 ^@ http://purl.uniprot.org/uniprot/H8N1P6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS4 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S5 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1144275:COCOR_RS27500 ^@ http://purl.uniprot.org/uniprot/H8MZ72 ^@ Function ^@ Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. http://togogenome.org/gene/1144275:COCOR_RS33300 ^@ http://purl.uniprot.org/uniprot/H8MXP8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1144275:COCOR_RS07830 ^@ http://purl.uniprot.org/uniprot/H8MWZ0 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1144275:COCOR_RS25520 ^@ http://purl.uniprot.org/uniprot/H8MRD2 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. http://togogenome.org/gene/1144275:COCOR_RS27725 ^@ http://purl.uniprot.org/uniprot/H8N0P9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PurK/PurT family.|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS18910 ^@ http://purl.uniprot.org/uniprot/H8MR11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS20795 ^@ http://purl.uniprot.org/uniprot/H8MXF0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CitM (TC 2.A.11) transporter family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37420 ^@ http://purl.uniprot.org/uniprot/H8MP13 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome ubiquinol oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37325 ^@ http://purl.uniprot.org/uniprot/H8MNZ4 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1144275:COCOR_RS26855 ^@ http://purl.uniprot.org/uniprot/H8MXF9 ^@ Function|||Subunit ^@ Heterodimer of an alpha and a beta chain.|||The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. http://togogenome.org/gene/1144275:COCOR_RS28245 ^@ http://purl.uniprot.org/uniprot/H8N264 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1144275:COCOR_RS35210 ^@ http://purl.uniprot.org/uniprot/H8MFX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS29145 ^@ http://purl.uniprot.org/uniprot/H8MH04 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04975 ^@ http://purl.uniprot.org/uniprot/H8MLL1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinylarginine dihydrolase family.|||Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS19260 ^@ http://purl.uniprot.org/uniprot/H8MSG6 ^@ Similarity|||Subunit ^@ Belongs to the ALAD family.|||Homooctamer. http://togogenome.org/gene/1144275:COCOR_RS37975 ^@ http://purl.uniprot.org/uniprot/H8MQH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS15130 ^@ http://purl.uniprot.org/uniprot/H8N1L0 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS29660 ^@ http://purl.uniprot.org/uniprot/H8MJK3 ^@ Similarity ^@ Belongs to the antibiotic N-acetyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS06845 ^@ http://purl.uniprot.org/uniprot/H8MTP2 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS19680 ^@ http://purl.uniprot.org/uniprot/H8MU22 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS25745 ^@ http://purl.uniprot.org/uniprot/H8MSQ9 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1144275:COCOR_RS26185 ^@ http://purl.uniprot.org/uniprot/H8MUB9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1144275:COCOR_RS21610 ^@ http://purl.uniprot.org/uniprot/H8N0M9 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1144275:COCOR_RS36875 ^@ http://purl.uniprot.org/uniprot/H8MMK2 ^@ Similarity ^@ Belongs to the group II decarboxylase family. http://togogenome.org/gene/1144275:COCOR_RS05875 ^@ http://purl.uniprot.org/uniprot/H8MQI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS22955 ^@ http://purl.uniprot.org/uniprot/H8MI16 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1144275:COCOR_RS20450 ^@ http://purl.uniprot.org/uniprot/H8MX80 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1144275:COCOR_RS37305 ^@ http://purl.uniprot.org/uniprot/H8MNZ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS10850 ^@ http://purl.uniprot.org/uniprot/H8MKC8 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS33635 ^@ http://purl.uniprot.org/uniprot/H8MXW6 ^@ Similarity ^@ Belongs to the universal stress protein A family. http://togogenome.org/gene/1144275:COCOR_RS05355 ^@ http://purl.uniprot.org/uniprot/H8MMY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35370 ^@ http://purl.uniprot.org/uniprot/H8MH52 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS01035 ^@ http://purl.uniprot.org/uniprot/H8MWJ4 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS23265 ^@ http://purl.uniprot.org/uniprot/H8MJC9 ^@ PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PAL/histidase family.|||Contains an active site 4-methylidene-imidazol-5-one (MIO), which is formed autocatalytically by cyclization and dehydration of residues Ala-Ser-Gly.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS04815 ^@ http://purl.uniprot.org/uniprot/H8MLH9 ^@ Similarity ^@ Belongs to the peptidase M20A family. ArgE subfamily. http://togogenome.org/gene/1144275:COCOR_RS01145 ^@ http://purl.uniprot.org/uniprot/H8MWL5 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1144275:COCOR_RS05565 ^@ http://purl.uniprot.org/uniprot/H8MP78 ^@ Function|||Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.|||Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine. http://togogenome.org/gene/1144275:COCOR_RS31410 ^@ http://purl.uniprot.org/uniprot/H8MQ53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32260 ^@ http://purl.uniprot.org/uniprot/H8MT09 ^@ Similarity|||Subcellular Location Annotation ^@ Cell inner membrane|||In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32070 ^@ http://purl.uniprot.org/uniprot/H8MSX0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS16050 ^@ http://purl.uniprot.org/uniprot/H8MGF1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS39275 ^@ http://purl.uniprot.org/uniprot/H8MWC0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily.|||Cell inner membrane|||Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system and for the release of the potassium ions to the cytoplasm.|||The system is composed of three essential subunits: KdpA, KdpB and KdpC. http://togogenome.org/gene/1144275:COCOR_RS03025 ^@ http://purl.uniprot.org/uniprot/H8MES5 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1144275:COCOR_RS36810 ^@ http://purl.uniprot.org/uniprot/H8MLD9 ^@ Similarity ^@ Belongs to the cytochrome c-552 family. http://togogenome.org/gene/1144275:COCOR_RS34545 ^@ http://purl.uniprot.org/uniprot/H8N2C0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1144275:COCOR_RS25660 ^@ http://purl.uniprot.org/uniprot/H8MSP3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08855 ^@ http://purl.uniprot.org/uniprot/H8N1G7 ^@ Similarity ^@ Belongs to the squalene monooxygenase family. http://togogenome.org/gene/1144275:COCOR_RS22860 ^@ http://purl.uniprot.org/uniprot/H8MHZ5 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS37450 ^@ http://purl.uniprot.org/uniprot/H8MP19 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Membrane|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1144275:COCOR_RS15165 ^@ http://purl.uniprot.org/uniprot/H8N1L7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1144275:COCOR_RS26965 ^@ http://purl.uniprot.org/uniprot/H8MXI1 ^@ Function|||Similarity ^@ Belongs to the MreC family.|||Involved in formation and maintenance of cell shape. http://togogenome.org/gene/1144275:COCOR_RS12055 ^@ http://purl.uniprot.org/uniprot/H8MPH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS01605 ^@ http://purl.uniprot.org/uniprot/H8MY87 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS24105 ^@ http://purl.uniprot.org/uniprot/H8MM48 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32810 ^@ http://purl.uniprot.org/uniprot/H8MUP3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily. http://togogenome.org/gene/1144275:COCOR_RS22640 ^@ http://purl.uniprot.org/uniprot/H8MGQ5 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1144275:COCOR_RS21925 ^@ http://purl.uniprot.org/uniprot/H8N201 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32325 ^@ http://purl.uniprot.org/uniprot/H8MT22 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1144275:COCOR_RS19585 ^@ http://purl.uniprot.org/uniprot/H8MSN1 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutL/HexB family.|||This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. http://togogenome.org/gene/1144275:COCOR_RS05110 ^@ http://purl.uniprot.org/uniprot/H8MMT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 4 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS27180 ^@ http://purl.uniprot.org/uniprot/H8MXM3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS06820 ^@ http://purl.uniprot.org/uniprot/H8MTN7 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).|||Belongs to the amidase family. GatA subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1144275:COCOR_RS00115 ^@ http://purl.uniprot.org/uniprot/H8MRY6 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1144275:COCOR_RS16485 ^@ http://purl.uniprot.org/uniprot/H8MHT7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS27835 ^@ http://purl.uniprot.org/uniprot/H8N0S2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP F family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS05425 ^@ http://purl.uniprot.org/uniprot/H8MN00 ^@ Similarity ^@ Belongs to the long-chain O-acyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS18015 ^@ http://purl.uniprot.org/uniprot/H8MN88 ^@ Similarity ^@ Belongs to the iron/ascorbate-dependent oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS07165 ^@ http://purl.uniprot.org/uniprot/H8MV84 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/1144275:COCOR_RS01550 ^@ http://purl.uniprot.org/uniprot/H8MY76 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS28810 ^@ http://purl.uniprot.org/uniprot/H8MFP2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1144275:COCOR_RS24035 ^@ http://purl.uniprot.org/uniprot/H8MM34 ^@ Function|||Similarity ^@ Belongs to the glucose-1-phosphate thymidylyltransferase family.|||Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. http://togogenome.org/gene/1144275:COCOR_RS03335 ^@ http://purl.uniprot.org/uniprot/H8MG37 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS06400 ^@ http://purl.uniprot.org/uniprot/H8MS27 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS03840 ^@ http://purl.uniprot.org/uniprot/H8MIN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13315 ^@ http://purl.uniprot.org/uniprot/H8MTX7 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1144275:COCOR_RS19535 ^@ http://purl.uniprot.org/uniprot/H8MSM1 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS18525 ^@ http://purl.uniprot.org/uniprot/H8MPN8 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the ThiC family.|||Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS25715 ^@ http://purl.uniprot.org/uniprot/H8MSQ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS33405 ^@ http://purl.uniprot.org/uniprot/H8MXS0 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS11910 ^@ http://purl.uniprot.org/uniprot/H8MPE3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.|||Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.|||Homotrimer. http://togogenome.org/gene/1144275:COCOR_RS33005 ^@ http://purl.uniprot.org/uniprot/H8MW62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS11210 ^@ http://purl.uniprot.org/uniprot/H8MLQ2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.|||Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.|||Cell inner membrane|||Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS17985 ^@ http://purl.uniprot.org/uniprot/H8MM32 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS37580 ^@ http://purl.uniprot.org/uniprot/H8MP45 ^@ Similarity ^@ Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. http://togogenome.org/gene/1144275:COCOR_RS04380 ^@ http://purl.uniprot.org/uniprot/H8MK41 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0187 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS23430 ^@ http://purl.uniprot.org/uniprot/H8MJG4 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1144275:COCOR_RS00415 ^@ http://purl.uniprot.org/uniprot/H8MTH7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS32080 ^@ http://purl.uniprot.org/uniprot/H8MSX2 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS28085 ^@ http://purl.uniprot.org/uniprot/H8N232 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10290 ^@ http://purl.uniprot.org/uniprot/H8MIW6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS18915 ^@ http://purl.uniprot.org/uniprot/H8MR12 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS30000 ^@ http://purl.uniprot.org/uniprot/H8MJS3 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1144275:COCOR_RS24710 ^@ http://purl.uniprot.org/uniprot/H8MNM2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1144275:COCOR_RS23845 ^@ http://purl.uniprot.org/uniprot/H8MKU5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0324 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22440 ^@ http://purl.uniprot.org/uniprot/H8MGL5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.|||Belongs to the RimM family.|||Binds ribosomal protein S19.|||Cytoplasm|||The PRC barrel domain binds ribosomal protein S19. http://togogenome.org/gene/1144275:COCOR_RS35230 ^@ http://purl.uniprot.org/uniprot/H8MH23 ^@ Similarity ^@ Belongs to the disproportionating enzyme family. http://togogenome.org/gene/1144275:COCOR_RS31240 ^@ http://purl.uniprot.org/uniprot/H8MNX1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS36690 ^@ http://purl.uniprot.org/uniprot/H8MLB5 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS22470 ^@ http://purl.uniprot.org/uniprot/H8MGM1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the succinate/malate CoA ligase alpha subunit family.|||Heterotetramer of two alpha and two beta subunits.|||Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. http://togogenome.org/gene/1144275:COCOR_RS19530 ^@ http://purl.uniprot.org/uniprot/H8MSM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).|||Belongs to the AccA family.|||Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS09795 ^@ http://purl.uniprot.org/uniprot/H8MGB9 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS11870 ^@ http://purl.uniprot.org/uniprot/H8MN83 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS15195 ^@ http://purl.uniprot.org/uniprot/H8N1M3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1144275:COCOR_RS05120 ^@ http://purl.uniprot.org/uniprot/H8MMT9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 4L family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS26190 ^@ http://purl.uniprot.org/uniprot/H8MUC0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoglycerate kinase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS08545 ^@ http://purl.uniprot.org/uniprot/H8N050 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS24830 ^@ http://purl.uniprot.org/uniprot/H8MPU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS17850 ^@ http://purl.uniprot.org/uniprot/H8MM06 ^@ Similarity ^@ Belongs to the peptidase S1C family. http://togogenome.org/gene/1144275:COCOR_RS38085 ^@ http://purl.uniprot.org/uniprot/H8MRP4 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS02940 ^@ http://purl.uniprot.org/uniprot/H8MEQ8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS17705 ^@ http://purl.uniprot.org/uniprot/H8MLX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS30790 ^@ http://purl.uniprot.org/uniprot/H8MMH8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0126 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS18170 ^@ http://purl.uniprot.org/uniprot/H8MNB9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS09320 ^@ http://purl.uniprot.org/uniprot/H8MEX9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS32425 ^@ http://purl.uniprot.org/uniprot/H8MT42 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1144275:COCOR_RS03990 ^@ http://purl.uniprot.org/uniprot/H8MIR0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS02120 ^@ http://purl.uniprot.org/uniprot/H8MZX0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDP-alcohol phosphatidyltransferase class-I family.|||Belongs to the GtrA family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30955 ^@ http://purl.uniprot.org/uniprot/H8MNR3 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1144275:COCOR_RS14125 ^@ http://purl.uniprot.org/uniprot/H8MX39 ^@ Subunit ^@ Homodimer. http://togogenome.org/gene/1144275:COCOR_RS05845 ^@ http://purl.uniprot.org/uniprot/H8MPD5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the dethiobiotin synthetase family.|||Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS32880 ^@ http://purl.uniprot.org/uniprot/H8MW37 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MsrP family.|||Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.|||Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).|||Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS27495 ^@ http://purl.uniprot.org/uniprot/H8MZ71 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS22420 ^@ http://purl.uniprot.org/uniprot/H8MFG5 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1144275:COCOR_RS25175 ^@ http://purl.uniprot.org/uniprot/H8MQ10 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS31180 ^@ http://purl.uniprot.org/uniprot/H8MNV9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.|||Cell inner membrane|||Forms a membrane-associated complex with FtsE.|||Membrane|||Part of the ABC transporter FtsEX involved in cellular division. http://togogenome.org/gene/1144275:COCOR_RS04010 ^@ http://purl.uniprot.org/uniprot/H8MIR4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1144275:COCOR_RS17205 ^@ http://purl.uniprot.org/uniprot/H8MKI1 ^@ Similarity|||Subunit ^@ Belongs to the sigma-70 factor family. ECF subfamily.|||Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS30825 ^@ http://purl.uniprot.org/uniprot/H8MMI5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS21920 ^@ http://purl.uniprot.org/uniprot/H8N200 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS18935 ^@ http://purl.uniprot.org/uniprot/H8MR16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS44075 ^@ http://purl.uniprot.org/uniprot/H8MYX8 ^@ Similarity ^@ In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1144275:COCOR_RS20480 ^@ http://purl.uniprot.org/uniprot/H8MX86 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1144275:COCOR_RS15290 ^@ http://purl.uniprot.org/uniprot/H8N1P2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1144275:COCOR_RS18315 ^@ http://purl.uniprot.org/uniprot/H8MNE7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS24915 ^@ http://purl.uniprot.org/uniprot/H8MPW0 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1144275:COCOR_RS11905 ^@ http://purl.uniprot.org/uniprot/H8MPE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS18560 ^@ http://purl.uniprot.org/uniprot/H8MPP5 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS15260 ^@ http://purl.uniprot.org/uniprot/H8N1N6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1144275:COCOR_RS12835 ^@ http://purl.uniprot.org/uniprot/H8MSA8 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1144275:COCOR_RS37000 ^@ http://purl.uniprot.org/uniprot/H8MMM7 ^@ Similarity ^@ Belongs to the LEA type 2 family. http://togogenome.org/gene/1144275:COCOR_RS16930 ^@ http://purl.uniprot.org/uniprot/H8MJ75 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS23200 ^@ http://purl.uniprot.org/uniprot/H8MI64 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TerC family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22200 ^@ http://purl.uniprot.org/uniprot/H8MFC3 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family. http://togogenome.org/gene/1144275:COCOR_RS25260 ^@ http://purl.uniprot.org/uniprot/H8MR79 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1144275:COCOR_RS31120 ^@ http://purl.uniprot.org/uniprot/H8MNU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. FtsY subfamily.|||Cell inner membrane|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Membrane|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1144275:COCOR_RS09765 ^@ http://purl.uniprot.org/uniprot/H8MGB7 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08915 ^@ http://purl.uniprot.org/uniprot/H8N1H9 ^@ Similarity ^@ Belongs to the asparaginase 1 family. http://togogenome.org/gene/1144275:COCOR_RS32415 ^@ http://purl.uniprot.org/uniprot/H8MT40 ^@ Similarity ^@ Belongs to the Cob(I)alamin adenosyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS22585 ^@ http://purl.uniprot.org/uniprot/H8MGP4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1144275:COCOR_RS30450 ^@ http://purl.uniprot.org/uniprot/H8ML60 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS05105 ^@ http://purl.uniprot.org/uniprot/H8MMT6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 2 family.|||Cell inner membrane|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS34515 ^@ http://purl.uniprot.org/uniprot/H8N2B4 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the ribulose-phosphate 3-epimerase family.|||Binds 1 divalent metal cation per subunit.|||Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate. http://togogenome.org/gene/1144275:COCOR_RS38325 ^@ http://purl.uniprot.org/uniprot/H8MRU2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreF family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1144275:COCOR_RS40425 ^@ http://purl.uniprot.org/uniprot/H8N141 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1144275:COCOR_RS22395 ^@ http://purl.uniprot.org/uniprot/H8MFG0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/1144275:COCOR_RS06675 ^@ http://purl.uniprot.org/uniprot/H8MTK8 ^@ Similarity|||Subunit ^@ Belongs to the threonine aldolase family.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS00695 ^@ http://purl.uniprot.org/uniprot/H8MV05 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS35565 ^@ http://purl.uniprot.org/uniprot/H8MH90 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1144275:COCOR_RS14790 ^@ http://purl.uniprot.org/uniprot/H8N086 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons. http://togogenome.org/gene/1144275:COCOR_RS15285 ^@ http://purl.uniprot.org/uniprot/H8N1P1 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS32145 ^@ http://purl.uniprot.org/uniprot/H8MSY6 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1144275:COCOR_RS28095 ^@ http://purl.uniprot.org/uniprot/H8N234 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliQ/MopD/SpaQ family.|||Cell membrane|||Membrane|||Role in flagellar biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS22630 ^@ http://purl.uniprot.org/uniprot/H8MGQ3 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1144275:COCOR_RS06955 ^@ http://purl.uniprot.org/uniprot/H8MTR5 ^@ Function|||Similarity ^@ Belongs to the peptidase S9A family.|||This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser. http://togogenome.org/gene/1144275:COCOR_RS22635 ^@ http://purl.uniprot.org/uniprot/H8MGQ4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Binds 2 Zn(2+) ions per subunit.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS24220 ^@ http://purl.uniprot.org/uniprot/H8MM69 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the XseB family.|||Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.|||Cytoplasm|||Heterooligomer composed of large and small subunits. http://togogenome.org/gene/1144275:COCOR_RS06355 ^@ http://purl.uniprot.org/uniprot/H8MS18 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. http://togogenome.org/gene/1144275:COCOR_RS15540 ^@ http://purl.uniprot.org/uniprot/H8MF09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0187 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS38935 ^@ http://purl.uniprot.org/uniprot/H8MUS1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1144275:COCOR_RS23425 ^@ http://purl.uniprot.org/uniprot/H8MJG3 ^@ Function|||Similarity ^@ Belongs to the helicase family. RecG subfamily.|||Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA). http://togogenome.org/gene/1144275:COCOR_RS22740 ^@ http://purl.uniprot.org/uniprot/H8MGS5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS34965 ^@ http://purl.uniprot.org/uniprot/H8MFS3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the acireductone dioxygenase (ARD) family.|||Binds 1 Fe(2+) cation per monomer.|||Binds 1 nickel ion per monomer.|||Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS24970 ^@ http://purl.uniprot.org/uniprot/H8MPX0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvT family.|||The glycine cleavage system catalyzes the degradation of glycine.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1144275:COCOR_RS32775 ^@ http://purl.uniprot.org/uniprot/H8MUN6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03390 ^@ http://purl.uniprot.org/uniprot/H8MG46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS32625 ^@ http://purl.uniprot.org/uniprot/H8MUK6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.|||Cytoplasm|||Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. http://togogenome.org/gene/1144275:COCOR_RS28455 ^@ http://purl.uniprot.org/uniprot/H8MFH2 ^@ Caution|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS04880 ^@ http://purl.uniprot.org/uniprot/H8MLJ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the etk/wzc family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS05215 ^@ http://purl.uniprot.org/uniprot/H8MMV8 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS17845 ^@ http://purl.uniprot.org/uniprot/H8MM05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1144275:COCOR_RS04060 ^@ http://purl.uniprot.org/uniprot/H8MIS4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS15190 ^@ http://purl.uniprot.org/uniprot/H8N1M2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL23 family.|||One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.|||Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome. http://togogenome.org/gene/1144275:COCOR_RS08625 ^@ http://purl.uniprot.org/uniprot/H8N066 ^@ Cofactor|||Similarity ^@ Belongs to the truncated hemoglobin family. Group I subfamily.|||Binds 1 heme group per subunit. http://togogenome.org/gene/1144275:COCOR_RS31910 ^@ http://purl.uniprot.org/uniprot/H8MRK5 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS12635 ^@ http://purl.uniprot.org/uniprot/H8MQY4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1144275:COCOR_RS17445 ^@ http://purl.uniprot.org/uniprot/H8MKM3 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS17315 ^@ http://purl.uniprot.org/uniprot/H8MKK1 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1144275:COCOR_RS34770 ^@ http://purl.uniprot.org/uniprot/H8N2G6 ^@ Cofactor|||Similarity ^@ Belongs to the 4HPPD family.|||Binds 1 Fe cation per subunit. http://togogenome.org/gene/1144275:COCOR_RS29710 ^@ http://purl.uniprot.org/uniprot/H8MJL3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS12355 ^@ http://purl.uniprot.org/uniprot/H8MQS9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS03945 ^@ http://purl.uniprot.org/uniprot/H8MIQ1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS33035 ^@ http://purl.uniprot.org/uniprot/H8MW68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 2 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS31080 ^@ http://purl.uniprot.org/uniprot/H8MNT9 ^@ Similarity ^@ Belongs to the peptidase S16 family. http://togogenome.org/gene/1144275:COCOR_RS13025 ^@ http://purl.uniprot.org/uniprot/H8MSE2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PstS family.|||Involved in the system for phosphate transport across the cytoplasmic membrane.|||Periplasm|||Secreted http://togogenome.org/gene/1144275:COCOR_RS18655 ^@ http://purl.uniprot.org/uniprot/H8MPR4 ^@ Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS22660 ^@ http://purl.uniprot.org/uniprot/H8MGQ9 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/1144275:COCOR_RS12085 ^@ http://purl.uniprot.org/uniprot/H8MPH8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS11880 ^@ http://purl.uniprot.org/uniprot/H8MPD7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS18775 ^@ http://purl.uniprot.org/uniprot/H8MPT9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS11080 ^@ http://purl.uniprot.org/uniprot/H8MLM7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS12265 ^@ http://purl.uniprot.org/uniprot/H8MPL3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS12410 ^@ http://purl.uniprot.org/uniprot/H8MQU0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1144275:COCOR_RS07245 ^@ http://purl.uniprot.org/uniprot/H8MVA0 ^@ Similarity ^@ Belongs to the class I fructose-bisphosphate aldolase family. http://togogenome.org/gene/1144275:COCOR_RS14985 ^@ http://purl.uniprot.org/uniprot/H8N0C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS29620 ^@ http://purl.uniprot.org/uniprot/H8MIE1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS10800 ^@ http://purl.uniprot.org/uniprot/H8MKB8 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS37585 ^@ http://purl.uniprot.org/uniprot/H8MP46 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS22750 ^@ http://purl.uniprot.org/uniprot/H8MGS7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS01555 ^@ http://purl.uniprot.org/uniprot/H8MY77 ^@ Similarity ^@ Belongs to the ribosome association toxin RatA family. http://togogenome.org/gene/1144275:COCOR_RS22450 ^@ http://purl.uniprot.org/uniprot/H8MGL7 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS16 family. http://togogenome.org/gene/1144275:COCOR_RS25355 ^@ http://purl.uniprot.org/uniprot/H8MR98 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1144275:COCOR_RS13090 ^@ http://purl.uniprot.org/uniprot/H8MSF5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1144275:COCOR_RS17750 ^@ http://purl.uniprot.org/uniprot/H8MLY6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PNP synthase family.|||Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.|||Cytoplasm|||Homooctamer; tetramer of dimers. http://togogenome.org/gene/1144275:COCOR_RS25185 ^@ http://purl.uniprot.org/uniprot/H8MQ12 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1144275:COCOR_RS19155 ^@ http://purl.uniprot.org/uniprot/H8MR62 ^@ Similarity ^@ Belongs to the AlaDH/PNT family. http://togogenome.org/gene/1144275:COCOR_RS29345 ^@ http://purl.uniprot.org/uniprot/H8MI88 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS00290 ^@ http://purl.uniprot.org/uniprot/H8MTF1 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS25680 ^@ http://purl.uniprot.org/uniprot/H8MSP6 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS24785 ^@ http://purl.uniprot.org/uniprot/H8MNN7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS19275 ^@ http://purl.uniprot.org/uniprot/H8MSG9 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1144275:COCOR_RS11185 ^@ http://purl.uniprot.org/uniprot/H8MLP8 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS25590 ^@ http://purl.uniprot.org/uniprot/H8MRE6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS06360 ^@ http://purl.uniprot.org/uniprot/H8MS19 ^@ PTM|||Similarity|||Subunit ^@ Belongs to the gamma-glutamyltransferase family.|||Cleaved by autocatalysis into a large and a small subunit.|||This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide. http://togogenome.org/gene/1144275:COCOR_RS27445 ^@ http://purl.uniprot.org/uniprot/H8MZ60 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS08525 ^@ http://purl.uniprot.org/uniprot/H8N046 ^@ Similarity ^@ Belongs to the peptidase S51 family. http://togogenome.org/gene/1144275:COCOR_RS39950 ^@ http://purl.uniprot.org/uniprot/H8MY34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS12010 ^@ http://purl.uniprot.org/uniprot/H8MPG3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1144275:COCOR_RS25165 ^@ http://purl.uniprot.org/uniprot/H8MQ08 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS29980 ^@ http://purl.uniprot.org/uniprot/H8MJR9 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1144275:COCOR_RS11085 ^@ http://purl.uniprot.org/uniprot/H8MLM8 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS13110 ^@ http://purl.uniprot.org/uniprot/H8MTT6 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS06860 ^@ http://purl.uniprot.org/uniprot/H8MTP5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL21 family.|||Part of the 50S ribosomal subunit. Contacts protein L20.|||This protein binds to 23S rRNA in the presence of protein L20. http://togogenome.org/gene/1144275:COCOR_RS06540 ^@ http://purl.uniprot.org/uniprot/H8MS56 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS03480 ^@ http://purl.uniprot.org/uniprot/H8MHB4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the auxin efflux carrier (TC 2.A.69) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS12435 ^@ http://purl.uniprot.org/uniprot/H8MQU5 ^@ Similarity ^@ Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family. http://togogenome.org/gene/1144275:COCOR_RS05285 ^@ http://purl.uniprot.org/uniprot/H8MMX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS17785 ^@ http://purl.uniprot.org/uniprot/H8MLZ3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the urocanase family.|||Binds 1 NAD(+) per subunit.|||Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS21040 ^@ http://purl.uniprot.org/uniprot/H8MYY0 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IMPDH/GMPR family.|||Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH. http://togogenome.org/gene/1144275:COCOR_RS24650 ^@ http://purl.uniprot.org/uniprot/H8MNL0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30265 ^@ http://purl.uniprot.org/uniprot/H8ML23 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1144275:COCOR_RS06275 ^@ http://purl.uniprot.org/uniprot/H8MS02 ^@ Function|||Similarity ^@ Belongs to the aconitase/IPM isomerase family.|||Catalyzes the isomerization of citrate to isocitrate via cis-aconitate. http://togogenome.org/gene/1144275:COCOR_RS09740 ^@ http://purl.uniprot.org/uniprot/H8MGB2 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1144275:COCOR_RS24455 ^@ http://purl.uniprot.org/uniprot/H8MNG8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS12845 ^@ http://purl.uniprot.org/uniprot/H8MSB0 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1144275:COCOR_RS29945 ^@ http://purl.uniprot.org/uniprot/H8MJR2 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS28110 ^@ http://purl.uniprot.org/uniprot/H8N237 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Belongs to the FliN/MopA/SpaO family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10075 ^@ http://purl.uniprot.org/uniprot/H8MHM9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1144275:COCOR_RS38800 ^@ http://purl.uniprot.org/uniprot/H8MTC1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1144275:COCOR_RS14025 ^@ http://purl.uniprot.org/uniprot/H8MX19 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS26260 ^@ http://purl.uniprot.org/uniprot/H8MUD4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS25400 ^@ http://purl.uniprot.org/uniprot/H8MRA7 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS14655 ^@ http://purl.uniprot.org/uniprot/H8MYS7 ^@ Similarity ^@ Belongs to the PhoH family. http://togogenome.org/gene/1144275:COCOR_RS26265 ^@ http://purl.uniprot.org/uniprot/H8MUD5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1144275:COCOR_RS02035 ^@ http://purl.uniprot.org/uniprot/H8MZV4 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS33675 ^@ http://purl.uniprot.org/uniprot/H8MZA6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 2 subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1144275:COCOR_RS11485 ^@ http://purl.uniprot.org/uniprot/H8MN05 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1144275:COCOR_RS05175 ^@ http://purl.uniprot.org/uniprot/H8MMV0 ^@ Similarity|||Subunit ^@ Belongs to the KdsC family.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS01720 ^@ http://purl.uniprot.org/uniprot/H8MYB0 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1144275:COCOR_RS03635 ^@ http://purl.uniprot.org/uniprot/H8MHE5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS02670 ^@ http://purl.uniprot.org/uniprot/H8MEK4 ^@ Similarity ^@ Belongs to the neutral ceramidase family. http://togogenome.org/gene/1144275:COCOR_RS06470 ^@ http://purl.uniprot.org/uniprot/H8MS42 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS06720 ^@ http://purl.uniprot.org/uniprot/H8MTL7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS05130 ^@ http://purl.uniprot.org/uniprot/H8MMU1 ^@ Function|||Similarity ^@ Belongs to the complex I 51 kDa subunit family.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. http://togogenome.org/gene/1144275:COCOR_RS34960 ^@ http://purl.uniprot.org/uniprot/H8MFS2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.|||Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).|||Binds 1 Mg(2+) ion per subunit.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS38330 ^@ http://purl.uniprot.org/uniprot/H8MRU3 ^@ Cofactor|||PTM|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.|||Binds 2 nickel ions per subunit.|||Carbamylation allows a single lysine to coordinate two nickel ions.|||Carboxylation allows a single lysine to coordinate two nickel ions.|||Cytoplasm|||Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme. http://togogenome.org/gene/1144275:COCOR_RS12200 ^@ http://purl.uniprot.org/uniprot/H8MPK1 ^@ Similarity ^@ Belongs to the diphosphomevalonate decarboxylase family. http://togogenome.org/gene/1144275:COCOR_RS15265 ^@ http://purl.uniprot.org/uniprot/H8N1N7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1144275:COCOR_RS20035 ^@ http://purl.uniprot.org/uniprot/H8MVM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS04065 ^@ http://purl.uniprot.org/uniprot/H8MIS5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS30675 ^@ http://purl.uniprot.org/uniprot/H8MMF5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliQ/MopD/SpaQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08845 ^@ http://purl.uniprot.org/uniprot/H8N1G5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS26780 ^@ http://purl.uniprot.org/uniprot/H8MW19 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS19590 ^@ http://purl.uniprot.org/uniprot/H8MSN2 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1144275:COCOR_RS36380 ^@ http://purl.uniprot.org/uniprot/H8MK02 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS20970 ^@ http://purl.uniprot.org/uniprot/H8MYW6 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1144275:COCOR_RS39040 ^@ http://purl.uniprot.org/uniprot/H8MUU2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS25740 ^@ http://purl.uniprot.org/uniprot/H8MSQ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS25640 ^@ http://purl.uniprot.org/uniprot/H8MSP0 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase class-2 family.|||Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. http://togogenome.org/gene/1144275:COCOR_RS30040 ^@ http://purl.uniprot.org/uniprot/H8MJT1 ^@ Caution|||Function|||Similarity ^@ Belongs to the dUTPase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. http://togogenome.org/gene/1144275:COCOR_RS35220 ^@ http://purl.uniprot.org/uniprot/H8MFX4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS31680 ^@ http://purl.uniprot.org/uniprot/H8MRF9 ^@ Function|||Similarity ^@ Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.|||Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1144275:COCOR_RS13055 ^@ http://purl.uniprot.org/uniprot/H8MSE8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS23395 ^@ http://purl.uniprot.org/uniprot/H8MJF7 ^@ Caution|||Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1144275:COCOR_RS13225 ^@ http://purl.uniprot.org/uniprot/H8MTV9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS12625 ^@ http://purl.uniprot.org/uniprot/H8MQY2 ^@ Function|||Similarity ^@ Belongs to the glutaredoxin family.|||Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. http://togogenome.org/gene/1144275:COCOR_RS10185 ^@ http://purl.uniprot.org/uniprot/H8MHP5 ^@ Similarity ^@ Belongs to the glutaredoxin family. Monothiol subfamily. http://togogenome.org/gene/1144275:COCOR_RS18345 ^@ http://purl.uniprot.org/uniprot/H8MNF2 ^@ Similarity ^@ Belongs to the BlaI transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS10035 ^@ http://purl.uniprot.org/uniprot/H8MHM1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1144275:COCOR_RS27490 ^@ http://purl.uniprot.org/uniprot/H8MZ70 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS12820 ^@ http://purl.uniprot.org/uniprot/H8MSA5 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.|||Cytoplasm|||Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.|||Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule. http://togogenome.org/gene/1144275:COCOR_RS01260 ^@ http://purl.uniprot.org/uniprot/H8MWN8 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS28225 ^@ http://purl.uniprot.org/uniprot/H8N260 ^@ Similarity ^@ Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily. http://togogenome.org/gene/1144275:COCOR_RS12670 ^@ http://purl.uniprot.org/uniprot/H8MQZ1 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1144275:COCOR_RS13005 ^@ http://purl.uniprot.org/uniprot/H8MSD8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PhoU family.|||Cytoplasm|||Homodimer.|||Plays a role in the regulation of phosphate uptake. http://togogenome.org/gene/1144275:COCOR_RS23650 ^@ http://purl.uniprot.org/uniprot/H8MKQ6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell inner membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1144275:COCOR_RS06960 ^@ http://purl.uniprot.org/uniprot/H8MTR6 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1144275:COCOR_RS24715 ^@ http://purl.uniprot.org/uniprot/H8MNM3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1144275:COCOR_RS22485 ^@ http://purl.uniprot.org/uniprot/H8MGM4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35125 ^@ http://purl.uniprot.org/uniprot/H8MFV5 ^@ Cofactor ^@ Can also use Mn(2+) ion. http://togogenome.org/gene/1144275:COCOR_RS21025 ^@ http://purl.uniprot.org/uniprot/H8MYX7 ^@ Similarity ^@ In the C-terminal section; belongs to the NRP synthetase family. http://togogenome.org/gene/1144275:COCOR_RS17940 ^@ http://purl.uniprot.org/uniprot/H8MM23 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1144275:COCOR_RS30635 ^@ http://purl.uniprot.org/uniprot/H8MME7 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1144275:COCOR_RS19735 ^@ http://purl.uniprot.org/uniprot/H8MU33 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS21020 ^@ http://purl.uniprot.org/uniprot/H8MYX6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DedA family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10820 ^@ http://purl.uniprot.org/uniprot/H8MKC2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS38120 ^@ http://purl.uniprot.org/uniprot/H8MRQ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1144275:COCOR_RS04245 ^@ http://purl.uniprot.org/uniprot/H8MK14 ^@ Similarity ^@ Belongs to the class-A beta-lactamase family. http://togogenome.org/gene/1144275:COCOR_RS35445 ^@ http://purl.uniprot.org/uniprot/H8MH66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the membrane-bound acyltransferase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS06595 ^@ http://purl.uniprot.org/uniprot/H8MS67 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS10060 ^@ http://purl.uniprot.org/uniprot/H8MHM6 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the selenophosphate synthase 1 family. Class I subfamily.|||Binds 1 Mg(2+) ion per monomer.|||Homodimer.|||Synthesizes selenophosphate from selenide and ATP. http://togogenome.org/gene/1144275:COCOR_RS31105 ^@ http://purl.uniprot.org/uniprot/H8MNU4 ^@ Similarity ^@ Belongs to the tRNA(His) guanylyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS21705 ^@ http://purl.uniprot.org/uniprot/H8N1V6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS37505 ^@ http://purl.uniprot.org/uniprot/H8MP30 ^@ Similarity ^@ Belongs to the UPF0337 (CsbD) family. http://togogenome.org/gene/1144275:COCOR_RS40075 ^@ http://purl.uniprot.org/uniprot/H8MZJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS36530 ^@ http://purl.uniprot.org/uniprot/H8ML83 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS25525 ^@ http://purl.uniprot.org/uniprot/H8MRD3 ^@ Similarity ^@ Belongs to the CFA/CMAS family. http://togogenome.org/gene/1144275:COCOR_RS18425 ^@ http://purl.uniprot.org/uniprot/H8MPL8 ^@ Similarity ^@ Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily. http://togogenome.org/gene/1144275:COCOR_RS25470 ^@ http://purl.uniprot.org/uniprot/H8MRC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatA/E family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1144275:COCOR_RS24825 ^@ http://purl.uniprot.org/uniprot/H8MNP4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1144275:COCOR_RS09885 ^@ http://purl.uniprot.org/uniprot/H8MHJ1 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS31555 ^@ http://purl.uniprot.org/uniprot/H8MQ83 ^@ Function|||Similarity ^@ Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.|||Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). http://togogenome.org/gene/1144275:COCOR_RS27800 ^@ http://purl.uniprot.org/uniprot/H8N0R5 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1144275:COCOR_RS23225 ^@ http://purl.uniprot.org/uniprot/H8MJC1 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS27525 ^@ http://purl.uniprot.org/uniprot/H8MZ77 ^@ Similarity ^@ Belongs to the RNase T2 family. http://togogenome.org/gene/1144275:COCOR_RS13300 ^@ http://purl.uniprot.org/uniprot/H8MTX4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS20675 ^@ http://purl.uniprot.org/uniprot/H8MXC6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1144275:COCOR_RS11675 ^@ http://purl.uniprot.org/uniprot/H8MN43 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS10815 ^@ http://purl.uniprot.org/uniprot/H8MKC1 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS05710 ^@ http://purl.uniprot.org/uniprot/H8MPA8 ^@ Similarity ^@ Belongs to the glycosyltransferase 20 family.|||In the C-terminal section; belongs to the trehalose phosphatase family.|||In the N-terminal section; belongs to the glycosyltransferase 20 family. http://togogenome.org/gene/1144275:COCOR_RS08135 ^@ http://purl.uniprot.org/uniprot/H8MYI6 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1144275:COCOR_RS07715 ^@ http://purl.uniprot.org/uniprot/H8MWW7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS09560 ^@ http://purl.uniprot.org/uniprot/H8MG75 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS39960 ^@ http://purl.uniprot.org/uniprot/H8MY36 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03910 ^@ http://purl.uniprot.org/uniprot/H8MIP4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1144275:COCOR_RS16075 ^@ http://purl.uniprot.org/uniprot/H8MGF6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase RluA family.|||Responsible for synthesis of pseudouridine from uracil. http://togogenome.org/gene/1144275:COCOR_RS42770 ^@ http://purl.uniprot.org/uniprot/H8MZ67 ^@ Function|||Similarity ^@ Belongs to the PemK/MazF family.|||Toxic component of a type II toxin-antitoxin (TA) system. http://togogenome.org/gene/1144275:COCOR_RS04350 ^@ http://purl.uniprot.org/uniprot/H8MK35 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the kynureninase family.|||Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS31150 ^@ http://purl.uniprot.org/uniprot/H8MNV3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS07870 ^@ http://purl.uniprot.org/uniprot/H8MYD1 ^@ Function|||Similarity ^@ Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.|||Belongs to the AhpD family. http://togogenome.org/gene/1144275:COCOR_RS05300 ^@ http://purl.uniprot.org/uniprot/H8MMX5 ^@ Function|||Similarity ^@ Belongs to the catalase family. HPII subfamily.|||Serves to protect cells from the toxic effects of hydrogen peroxide. http://togogenome.org/gene/1144275:COCOR_RS15970 ^@ http://purl.uniprot.org/uniprot/H8MGD6 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS21900 ^@ http://purl.uniprot.org/uniprot/H8N1Z6 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1144275:COCOR_RS24145 ^@ http://purl.uniprot.org/uniprot/H8MM54 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1144275:COCOR_RS05430 ^@ http://purl.uniprot.org/uniprot/H8MN01 ^@ Similarity ^@ Belongs to the oxygen-dependent FAD-linked oxidoreductase family. http://togogenome.org/gene/1144275:COCOR_RS14425 ^@ http://purl.uniprot.org/uniprot/H8MYN3 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS32910 ^@ http://purl.uniprot.org/uniprot/H8MW43 ^@ Similarity ^@ Belongs to the peptidase S8 family. http://togogenome.org/gene/1144275:COCOR_RS36885 ^@ http://purl.uniprot.org/uniprot/H8MMK4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cytoplasm|||Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.|||Forms polymers. http://togogenome.org/gene/1144275:COCOR_RS05560 ^@ http://purl.uniprot.org/uniprot/H8MP77 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1144275:COCOR_RS17775 ^@ http://purl.uniprot.org/uniprot/H8MLZ1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30145 ^@ http://purl.uniprot.org/uniprot/H8ML03 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PanB family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.|||Cytoplasm|||Homodecamer; pentamer of dimers. http://togogenome.org/gene/1144275:COCOR_RS11175 ^@ http://purl.uniprot.org/uniprot/H8MLP6 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS18025 ^@ http://purl.uniprot.org/uniprot/H8MN90 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. HMG-CoA synthase family. http://togogenome.org/gene/1144275:COCOR_RS28515 ^@ http://purl.uniprot.org/uniprot/H8MFI5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS40020 ^@ http://purl.uniprot.org/uniprot/H8MZI0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NrfD family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS38055 ^@ http://purl.uniprot.org/uniprot/H8MRN8 ^@ Similarity ^@ Belongs to the glyoxalase I family. http://togogenome.org/gene/1144275:COCOR_RS03395 ^@ http://purl.uniprot.org/uniprot/H8MG47 ^@ Similarity ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS01860 ^@ http://purl.uniprot.org/uniprot/H8MZR9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OmpP1/FadL family.|||Cell outer membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22895 ^@ http://purl.uniprot.org/uniprot/H8MI02 ^@ Subcellular Location Annotation ^@ Secreted http://togogenome.org/gene/1144275:COCOR_RS02055 ^@ http://purl.uniprot.org/uniprot/H8MZV8 ^@ Similarity ^@ Belongs to the band 7/mec-2 family. http://togogenome.org/gene/1144275:COCOR_RS01600 ^@ http://purl.uniprot.org/uniprot/H8MY86 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1144275:COCOR_RS07755 ^@ http://purl.uniprot.org/uniprot/H8MWX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SUA5 family.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. http://togogenome.org/gene/1144275:COCOR_RS24405 ^@ http://purl.uniprot.org/uniprot/H8MMA6 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1144275:COCOR_RS37615 ^@ http://purl.uniprot.org/uniprot/H8MP52 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1144275:COCOR_RS09370 ^@ http://purl.uniprot.org/uniprot/H8MEY8 ^@ Similarity ^@ Belongs to the myoviridae tail sheath protein family. http://togogenome.org/gene/1144275:COCOR_RS31700 ^@ http://purl.uniprot.org/uniprot/H8MRG3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30455 ^@ http://purl.uniprot.org/uniprot/H8ML61 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS27865 ^@ http://purl.uniprot.org/uniprot/H8N0S9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP K family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22690 ^@ http://purl.uniprot.org/uniprot/H8MGR5 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1144275:COCOR_RS30920 ^@ http://purl.uniprot.org/uniprot/H8MNQ6 ^@ Similarity|||Subunit ^@ Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS36230 ^@ http://purl.uniprot.org/uniprot/H8MJX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS13515 ^@ http://purl.uniprot.org/uniprot/H8MVE4 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1144275:COCOR_RS05825 ^@ http://purl.uniprot.org/uniprot/H8MPD1 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1144275:COCOR_RS07980 ^@ http://purl.uniprot.org/uniprot/H8MYF4 ^@ Similarity ^@ In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1144275:COCOR_RS21205 ^@ http://purl.uniprot.org/uniprot/H8MZ15 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS33080 ^@ http://purl.uniprot.org/uniprot/H8MW77 ^@ Similarity ^@ Belongs to the AB hydrolase superfamily. AB hydrolase 4 family. http://togogenome.org/gene/1144275:COCOR_RS10955 ^@ http://purl.uniprot.org/uniprot/H8MKE9 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family.|||In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS26450 ^@ http://purl.uniprot.org/uniprot/H8MVV3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04545 ^@ http://purl.uniprot.org/uniprot/H8MK75 ^@ Function|||Similarity ^@ Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.|||Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. http://togogenome.org/gene/1144275:COCOR_RS27510 ^@ http://purl.uniprot.org/uniprot/H8MZ74 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS40300 ^@ http://purl.uniprot.org/uniprot/H8MZN7 ^@ Function|||Similarity ^@ Belongs to the ParB family.|||Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication. http://togogenome.org/gene/1144275:COCOR_RS36350 ^@ http://purl.uniprot.org/uniprot/H8MJZ6 ^@ Similarity ^@ Belongs to the LarC family. http://togogenome.org/gene/1144275:COCOR_RS16805 ^@ http://purl.uniprot.org/uniprot/H8MJ50 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS22365 ^@ http://purl.uniprot.org/uniprot/H8MFF6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS36985 ^@ http://purl.uniprot.org/uniprot/H8MMM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS02835 ^@ http://purl.uniprot.org/uniprot/H8MEN7 ^@ Similarity ^@ Belongs to the OsmC/Ohr family. http://togogenome.org/gene/1144275:COCOR_RS04665 ^@ http://purl.uniprot.org/uniprot/H8MLE9 ^@ Similarity ^@ Belongs to the pirin family. http://togogenome.org/gene/1144275:COCOR_RS27455 ^@ http://purl.uniprot.org/uniprot/H8MZ62 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS35375 ^@ http://purl.uniprot.org/uniprot/H8MH53 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane|||Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. http://togogenome.org/gene/1144275:COCOR_RS14900 ^@ http://purl.uniprot.org/uniprot/H8N0A7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial sugar transferase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS34950 ^@ http://purl.uniprot.org/uniprot/H8MFS0 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1144275:COCOR_RS05115 ^@ http://purl.uniprot.org/uniprot/H8MMT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS00755 ^@ http://purl.uniprot.org/uniprot/H8MV16 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Maintains high levels of reduced glutathione. http://togogenome.org/gene/1144275:COCOR_RS11305 ^@ http://purl.uniprot.org/uniprot/H8MLS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS36790 ^@ http://purl.uniprot.org/uniprot/H8MLD5 ^@ Activity Regulation|||Caution|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS14480 ^@ http://purl.uniprot.org/uniprot/H8MYP4 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1144275:COCOR_RS27030 ^@ http://purl.uniprot.org/uniprot/H8MXJ3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1144275:COCOR_RS10240 ^@ http://purl.uniprot.org/uniprot/H8MHQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.|||Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS13770 ^@ http://purl.uniprot.org/uniprot/H8MVJ5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-I fumarase family.|||Catalyzes the reversible hydration of fumarate to (S)-malate.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS13085 ^@ http://purl.uniprot.org/uniprot/H8MSF4 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1144275:COCOR_RS05660 ^@ http://purl.uniprot.org/uniprot/H8MP97 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS19825 ^@ http://purl.uniprot.org/uniprot/H8MU51 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1144275:COCOR_RS26240 ^@ http://purl.uniprot.org/uniprot/H8MUD0 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS10555 ^@ http://purl.uniprot.org/uniprot/H8MJ18 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS14925 ^@ http://purl.uniprot.org/uniprot/H8N0B2 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS02705 ^@ http://purl.uniprot.org/uniprot/H8MEL1 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS14340 ^@ http://purl.uniprot.org/uniprot/H8MYL6 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1144275:COCOR_RS17435 ^@ http://purl.uniprot.org/uniprot/H8MKM1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS26325 ^@ http://purl.uniprot.org/uniprot/H8MUE7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the lipase chaperone family.|||Cell inner membrane|||May be involved in the folding of the extracellular lipase during its passage through the periplasm. http://togogenome.org/gene/1144275:COCOR_RS13130 ^@ http://purl.uniprot.org/uniprot/H8MTU0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the NrdR family.|||Binds 1 zinc ion.|||Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes. http://togogenome.org/gene/1144275:COCOR_RS32820 ^@ http://purl.uniprot.org/uniprot/H8MUP5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the 2-oxoacid dehydrogenase family.|||Binds 1 lipoyl cofactor covalently.|||E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1144275:COCOR_RS38345 ^@ http://purl.uniprot.org/uniprot/H8MRU6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UreD family.|||Cytoplasm|||Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.|||UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1144275:COCOR_RS13730 ^@ http://purl.uniprot.org/uniprot/H8MVI7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS26530 ^@ http://purl.uniprot.org/uniprot/H8MVW9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I subunit 1 family.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. http://togogenome.org/gene/1144275:COCOR_RS30510 ^@ http://purl.uniprot.org/uniprot/H8MMC2 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the MraZ family.|||Forms oligomers.|||nucleoid http://togogenome.org/gene/1144275:COCOR_RS06750 ^@ http://purl.uniprot.org/uniprot/H8MTM3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS02130 ^@ http://purl.uniprot.org/uniprot/H8MZX2 ^@ Similarity ^@ Belongs to the myo-inositol 1-phosphate synthase family. http://togogenome.org/gene/1144275:COCOR_RS12655 ^@ http://purl.uniprot.org/uniprot/H8MQY8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase subunit omega family.|||Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS09305 ^@ http://purl.uniprot.org/uniprot/H8MEX6 ^@ Similarity ^@ Belongs to the BshC family. http://togogenome.org/gene/1144275:COCOR_RS44265 ^@ http://purl.uniprot.org/uniprot/H8MY91 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS32675 ^@ http://purl.uniprot.org/uniprot/H8MUL6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S33 family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS22745 ^@ http://purl.uniprot.org/uniprot/H8MGS6 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS08785 ^@ http://purl.uniprot.org/uniprot/H8N1F3 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS24040 ^@ http://purl.uniprot.org/uniprot/H8MM35 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Binds 1 Mg(2+) ion per monomer.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1144275:COCOR_RS38790 ^@ http://purl.uniprot.org/uniprot/H8MTB9 ^@ Cofactor|||Similarity ^@ Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit. http://togogenome.org/gene/1144275:COCOR_RS33640 ^@ http://purl.uniprot.org/uniprot/H8MXW7 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS11345 ^@ http://purl.uniprot.org/uniprot/H8MLT0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS09875 ^@ http://purl.uniprot.org/uniprot/H8MHI9 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1144275:COCOR_RS36385 ^@ http://purl.uniprot.org/uniprot/H8MK03 ^@ Caution|||Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1144275:COCOR_RS33395 ^@ http://purl.uniprot.org/uniprot/H8MXR8 ^@ Caution|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the IcmF family.|||Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.|||Homodimer.|||Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS21005 ^@ http://purl.uniprot.org/uniprot/H8MYX3 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the methylthiotransferase family. MiaB subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS21775 ^@ http://purl.uniprot.org/uniprot/H8N1X0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS23690 ^@ http://purl.uniprot.org/uniprot/H8MKR4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS16655 ^@ http://purl.uniprot.org/uniprot/H8MHX1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1144275:COCOR_RS34010 ^@ http://purl.uniprot.org/uniprot/H8MZH4 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS18660 ^@ http://purl.uniprot.org/uniprot/H8MPR5 ^@ Similarity ^@ Belongs to the ClpX chaperone family. http://togogenome.org/gene/1144275:COCOR_RS35090 ^@ http://purl.uniprot.org/uniprot/H8MFU8 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.|||Cytoplasm|||Homotetramer.|||Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.|||There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors. http://togogenome.org/gene/1144275:COCOR_RS07670 ^@ http://purl.uniprot.org/uniprot/H8MWV7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.|||Homotetramer.|||Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc. http://togogenome.org/gene/1144275:COCOR_RS22180 ^@ http://purl.uniprot.org/uniprot/H8MFC0 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1144275:COCOR_RS21770 ^@ http://purl.uniprot.org/uniprot/H8N1W9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS26650 ^@ http://purl.uniprot.org/uniprot/H8MVZ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS05930 ^@ http://purl.uniprot.org/uniprot/H8MQJ9 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity. http://togogenome.org/gene/1144275:COCOR_RS24240 ^@ http://purl.uniprot.org/uniprot/H8MM73 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS23175 ^@ http://purl.uniprot.org/uniprot/H8MI59 ^@ Similarity ^@ Belongs to the allantoicase family. http://togogenome.org/gene/1144275:COCOR_RS27840 ^@ http://purl.uniprot.org/uniprot/H8N0S4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GSP G family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS01265 ^@ http://purl.uniprot.org/uniprot/H8MWN9 ^@ Similarity ^@ Belongs to the ribose-phosphate pyrophosphokinase family. http://togogenome.org/gene/1144275:COCOR_RS05255 ^@ http://purl.uniprot.org/uniprot/H8MMW6 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 Mg(2+) ion per subunit.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.|||In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS39550 ^@ http://purl.uniprot.org/uniprot/H8MWH5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the major facilitator superfamily. Bcr/CmlA family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35385 ^@ http://purl.uniprot.org/uniprot/H8MH55 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS10165 ^@ http://purl.uniprot.org/uniprot/H8MHP1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS11035 ^@ http://purl.uniprot.org/uniprot/H8MKG6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS09860 ^@ http://purl.uniprot.org/uniprot/H8MHI6 ^@ Similarity ^@ Belongs to the UPF0758 family. http://togogenome.org/gene/1144275:COCOR_RS27200 ^@ http://purl.uniprot.org/uniprot/H8MXM7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the quinolinate synthase family. Type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS20885 ^@ http://purl.uniprot.org/uniprot/H8MYU9 ^@ Function|||Similarity ^@ Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.|||Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. http://togogenome.org/gene/1144275:COCOR_RS28545 ^@ http://purl.uniprot.org/uniprot/H8MFJ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||In the N-terminal section; belongs to the FGAMS family.|||Monomer.|||Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. http://togogenome.org/gene/1144275:COCOR_RS11070 ^@ http://purl.uniprot.org/uniprot/H8MLM5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1144275:COCOR_RS31800 ^@ http://purl.uniprot.org/uniprot/H8MRI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic sulfate-binding protein family.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS19540 ^@ http://purl.uniprot.org/uniprot/H8MSM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS38815 ^@ http://purl.uniprot.org/uniprot/H8MTC4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS35120 ^@ http://purl.uniprot.org/uniprot/H8MFV4 ^@ Similarity ^@ Belongs to the malate synthase family. http://togogenome.org/gene/1144275:COCOR_RS09870 ^@ http://purl.uniprot.org/uniprot/H8MHI8 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS34955 ^@ http://purl.uniprot.org/uniprot/H8MFS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.|||Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.|||Homohexamer. Dimer of a homotrimer. http://togogenome.org/gene/1144275:COCOR_RS07215 ^@ http://purl.uniprot.org/uniprot/H8MV94 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS06745 ^@ http://purl.uniprot.org/uniprot/H8MTM2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS39530 ^@ http://purl.uniprot.org/uniprot/H8MWH1 ^@ Similarity ^@ Belongs to the bacterial reverse transcriptase family. http://togogenome.org/gene/1144275:COCOR_RS13065 ^@ http://purl.uniprot.org/uniprot/H8MSF0 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1144275:COCOR_RS25215 ^@ http://purl.uniprot.org/uniprot/H8MQ18 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmG family. TrmFO subfamily.|||Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS01235 ^@ http://purl.uniprot.org/uniprot/H8MWN3 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1144275:COCOR_RS23605 ^@ http://purl.uniprot.org/uniprot/H8MJJ7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1144275:COCOR_RS12570 ^@ http://purl.uniprot.org/uniprot/H8MQX0 ^@ Similarity ^@ Belongs to the CapA family. http://togogenome.org/gene/1144275:COCOR_RS32900 ^@ http://purl.uniprot.org/uniprot/H8MW41 ^@ Function|||Similarity ^@ Belongs to the ketopantoate reductase family.|||Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. http://togogenome.org/gene/1144275:COCOR_RS11970 ^@ http://purl.uniprot.org/uniprot/H8MPF5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1144275:COCOR_RS30800 ^@ http://purl.uniprot.org/uniprot/H8MMI0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS08875 ^@ http://purl.uniprot.org/uniprot/H8N1H1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS19500 ^@ http://purl.uniprot.org/uniprot/H8MSL4 ^@ Similarity ^@ Belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1144275:COCOR_RS24205 ^@ http://purl.uniprot.org/uniprot/H8MM66 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS33255 ^@ http://purl.uniprot.org/uniprot/H8MXN9 ^@ Similarity ^@ Belongs to the peptidase S45 family. http://togogenome.org/gene/1144275:COCOR_RS23105 ^@ http://purl.uniprot.org/uniprot/H8MI45 ^@ Function|||Similarity ^@ Belongs to the APS kinase family.|||Catalyzes the synthesis of activated sulfate. http://togogenome.org/gene/1144275:COCOR_RS26535 ^@ http://purl.uniprot.org/uniprot/H8MVX0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the complex I 23 kDa subunit family.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS30480 ^@ http://purl.uniprot.org/uniprot/H8MMB6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family. MurF subfamily.|||Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1144275:COCOR_RS25735 ^@ http://purl.uniprot.org/uniprot/H8MSQ7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS26875 ^@ http://purl.uniprot.org/uniprot/H8MXG3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS32190 ^@ http://purl.uniprot.org/uniprot/H8MSZ5 ^@ PTM ^@ The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1144275:COCOR_RS31430 ^@ http://purl.uniprot.org/uniprot/H8MQ57 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS40380 ^@ http://purl.uniprot.org/uniprot/H8MZQ3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S49 family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS16665 ^@ http://purl.uniprot.org/uniprot/H8MHX3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS42660 ^@ http://purl.uniprot.org/uniprot/H8MPA1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS05755 ^@ http://purl.uniprot.org/uniprot/H8MPB7 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1144275:COCOR_RS20030 ^@ http://purl.uniprot.org/uniprot/H8MVM3 ^@ Similarity ^@ Belongs to the prespore-cell-inducing factor family. http://togogenome.org/gene/1144275:COCOR_RS31645 ^@ http://purl.uniprot.org/uniprot/H8MQA0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the YqgF HJR family.|||Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS05125 ^@ http://purl.uniprot.org/uniprot/H8MMU0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the complex I subunit 6 family.|||Cell membrane|||NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. http://togogenome.org/gene/1144275:COCOR_RS31890 ^@ http://purl.uniprot.org/uniprot/H8MRK1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35640 ^@ http://purl.uniprot.org/uniprot/H8MIF0 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1144275:COCOR_RS35580 ^@ http://purl.uniprot.org/uniprot/H8MH93 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS08045 ^@ http://purl.uniprot.org/uniprot/H8MYG8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS26310 ^@ http://purl.uniprot.org/uniprot/H8MUE4 ^@ Similarity ^@ Belongs to the asparagine synthetase family. http://togogenome.org/gene/1144275:COCOR_RS25550 ^@ http://purl.uniprot.org/uniprot/H8MRD8 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1144275:COCOR_RS18920 ^@ http://purl.uniprot.org/uniprot/H8MR13 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS22545 ^@ http://purl.uniprot.org/uniprot/H8MGN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MenA family. Type 1 subfamily.|||Cell inner membrane|||Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).|||Membrane http://togogenome.org/gene/1144275:COCOR_RS39420 ^@ http://purl.uniprot.org/uniprot/H8MWF0 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS32315 ^@ http://purl.uniprot.org/uniprot/H8MT20 ^@ Similarity ^@ Belongs to the ETF beta-subunit/FixA family. http://togogenome.org/gene/1144275:COCOR_RS19390 ^@ http://purl.uniprot.org/uniprot/H8MSJ2 ^@ Similarity ^@ Belongs to the DEAD box helicase family. http://togogenome.org/gene/1144275:COCOR_RS05680 ^@ http://purl.uniprot.org/uniprot/H8MPA2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the spermidine/spermine synthase family.|||Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.|||Cell membrane|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS33030 ^@ http://purl.uniprot.org/uniprot/H8MW67 ^@ Similarity ^@ Belongs to the SCO1/2 family. http://togogenome.org/gene/1144275:COCOR_RS27255 ^@ http://purl.uniprot.org/uniprot/H8MZ20 ^@ Similarity ^@ Belongs to the HesB/IscA family. http://togogenome.org/gene/1144275:COCOR_RS38060 ^@ http://purl.uniprot.org/uniprot/H8MRN9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS06105 ^@ http://purl.uniprot.org/uniprot/H8MQN4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS04505 ^@ http://purl.uniprot.org/uniprot/H8MK66 ^@ Similarity ^@ Belongs to the peptidase S1 family. http://togogenome.org/gene/1144275:COCOR_RS16100 ^@ http://purl.uniprot.org/uniprot/H8MGG1 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1144275:COCOR_RS34525 ^@ http://purl.uniprot.org/uniprot/H8N2B6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1144275:COCOR_RS30020 ^@ http://purl.uniprot.org/uniprot/H8MJS7 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1144275:COCOR_RS17980 ^@ http://purl.uniprot.org/uniprot/H8MM31 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1144275:COCOR_RS11945 ^@ http://purl.uniprot.org/uniprot/H8MPF0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1144275:COCOR_RS15180 ^@ http://purl.uniprot.org/uniprot/H8N1M0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1144275:COCOR_RS27625 ^@ http://purl.uniprot.org/uniprot/H8MZ98 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CDS family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37125 ^@ http://purl.uniprot.org/uniprot/H8MMQ2 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS33905 ^@ http://purl.uniprot.org/uniprot/H8MZF2 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS16460 ^@ http://purl.uniprot.org/uniprot/H8MHT2 ^@ Function|||Similarity ^@ Belongs to the iron/manganese superoxide dismutase family.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1144275:COCOR_RS24210 ^@ http://purl.uniprot.org/uniprot/H8MM67 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1144275:COCOR_RS33140 ^@ http://purl.uniprot.org/uniprot/H8MW89 ^@ Similarity ^@ Belongs to the peptidase M4 family. http://togogenome.org/gene/1144275:COCOR_RS15070 ^@ http://purl.uniprot.org/uniprot/H8N0E2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22170 ^@ http://purl.uniprot.org/uniprot/H8MFB8 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1144275:COCOR_RS33260 ^@ http://purl.uniprot.org/uniprot/H8MXP0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm|||Modulates RecA activity. http://togogenome.org/gene/1144275:COCOR_RS13625 ^@ http://purl.uniprot.org/uniprot/H8MVG6 ^@ Caution|||Function|||Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.|||Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS34090 ^@ http://purl.uniprot.org/uniprot/H8N0X1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 13 family. http://togogenome.org/gene/1144275:COCOR_RS27140 ^@ http://purl.uniprot.org/uniprot/H8MXL5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS25935 ^@ http://purl.uniprot.org/uniprot/H8MSU7 ^@ Similarity ^@ Belongs to the type-B carboxylesterase/lipase family. http://togogenome.org/gene/1144275:COCOR_RS21695 ^@ http://purl.uniprot.org/uniprot/H8N1V4 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1144275:COCOR_RS05480 ^@ http://purl.uniprot.org/uniprot/H8MP61 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS30470 ^@ http://purl.uniprot.org/uniprot/H8MMB4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS33390 ^@ http://purl.uniprot.org/uniprot/H8MXR7 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily. http://togogenome.org/gene/1144275:COCOR_RS19370 ^@ http://purl.uniprot.org/uniprot/H8MSI9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS19700 ^@ http://purl.uniprot.org/uniprot/H8MU26 ^@ Similarity ^@ Belongs to the DNA polymerase type-Y family. http://togogenome.org/gene/1144275:COCOR_RS13320 ^@ http://purl.uniprot.org/uniprot/H8MTX8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the transferase hexapeptide repeat family. LpxD subfamily.|||Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.|||Homotrimer. http://togogenome.org/gene/1144275:COCOR_RS00130 ^@ http://purl.uniprot.org/uniprot/H8MRY9 ^@ Similarity ^@ Belongs to the prokaryotic GSH synthase family. http://togogenome.org/gene/1144275:COCOR_RS32485 ^@ http://purl.uniprot.org/uniprot/H8MUH6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS08955 ^@ http://purl.uniprot.org/uniprot/H8N1I7 ^@ Similarity ^@ Belongs to the outer membrane factor (OMF) (TC 1.B.17) family. http://togogenome.org/gene/1144275:COCOR_RS01020 ^@ http://purl.uniprot.org/uniprot/H8MWJ1 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS28090 ^@ http://purl.uniprot.org/uniprot/H8N233 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliR/MopE/SpaR family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS04370 ^@ http://purl.uniprot.org/uniprot/H8MK39 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS20895 ^@ http://purl.uniprot.org/uniprot/H8MYV1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S49 family.|||Cell inner membrane http://togogenome.org/gene/1144275:COCOR_RS09925 ^@ http://purl.uniprot.org/uniprot/H8MHJ9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS33270 ^@ http://purl.uniprot.org/uniprot/H8MXP2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1144275:COCOR_RS00045 ^@ http://purl.uniprot.org/uniprot/H8MRX3 ^@ Similarity ^@ In the C-terminal section; belongs to the homoserine dehydrogenase family.|||In the N-terminal section; belongs to the aspartokinase family. http://togogenome.org/gene/1144275:COCOR_RS15470 ^@ http://purl.uniprot.org/uniprot/H8N1S6 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS22940 ^@ http://purl.uniprot.org/uniprot/H8MI13 ^@ Similarity ^@ Belongs to the GST superfamily. http://togogenome.org/gene/1144275:COCOR_RS06370 ^@ http://purl.uniprot.org/uniprot/H8MS21 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1144275:COCOR_RS06485 ^@ http://purl.uniprot.org/uniprot/H8MS45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M4 family.|||Extracellular zinc metalloprotease.|||Secreted http://togogenome.org/gene/1144275:COCOR_RS31085 ^@ http://purl.uniprot.org/uniprot/H8MNU0 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS17335 ^@ http://purl.uniprot.org/uniprot/H8MKK5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the DNA gyrase inhibitor YacG family.|||Binds 1 zinc ion.|||Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.|||Interacts with GyrB. http://togogenome.org/gene/1144275:COCOR_RS22820 ^@ http://purl.uniprot.org/uniprot/H8MGU1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum|||Golgi apparatus|||Lysosome|||Secreted http://togogenome.org/gene/1144275:COCOR_RS08865 ^@ http://purl.uniprot.org/uniprot/H8N1G9 ^@ Similarity ^@ Belongs to the terpene cyclase/mutase family. http://togogenome.org/gene/1144275:COCOR_RS29565 ^@ http://purl.uniprot.org/uniprot/H8MID0 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the homogentisate dioxygenase family.|||Hexamer; dimer of trimers.|||Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS23745 ^@ http://purl.uniprot.org/uniprot/H8MKS5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS37970 ^@ http://purl.uniprot.org/uniprot/H8MQG9 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35365 ^@ http://purl.uniprot.org/uniprot/H8MH51 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30445 ^@ http://purl.uniprot.org/uniprot/H8ML59 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS30100 ^@ http://purl.uniprot.org/uniprot/H8MKZ4 ^@ Similarity ^@ Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family. http://togogenome.org/gene/1144275:COCOR_RS02460 ^@ http://purl.uniprot.org/uniprot/H8N195 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-2 integral membrane protein family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08610 ^@ http://purl.uniprot.org/uniprot/H8N063 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0410 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30160 ^@ http://purl.uniprot.org/uniprot/H8ML06 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1144275:COCOR_RS25055 ^@ http://purl.uniprot.org/uniprot/H8MPY7 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. http://togogenome.org/gene/1144275:COCOR_RS00985 ^@ http://purl.uniprot.org/uniprot/H8MV61 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS11075 ^@ http://purl.uniprot.org/uniprot/H8MLM6 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS2 family. http://togogenome.org/gene/1144275:COCOR_RS27350 ^@ http://purl.uniprot.org/uniprot/H8MZ41 ^@ Caution|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS12580 ^@ http://purl.uniprot.org/uniprot/H8MQX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS27630 ^@ http://purl.uniprot.org/uniprot/H8MZ99 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS09155 ^@ http://purl.uniprot.org/uniprot/H8MEU5 ^@ Similarity ^@ Belongs to the Gfa family. http://togogenome.org/gene/1144275:COCOR_RS21225 ^@ http://purl.uniprot.org/uniprot/H8MZ19 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS25395 ^@ http://purl.uniprot.org/uniprot/H8MRA6 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS26235 ^@ http://purl.uniprot.org/uniprot/H8MUC9 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS02800 ^@ http://purl.uniprot.org/uniprot/H8MEN0 ^@ Similarity ^@ Belongs to the peptidase M1 family. http://togogenome.org/gene/1144275:COCOR_RS14500 ^@ http://purl.uniprot.org/uniprot/H8MYP8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS36575 ^@ http://purl.uniprot.org/uniprot/H8ML92 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1144275:COCOR_RS06305 ^@ http://purl.uniprot.org/uniprot/H8MS08 ^@ Similarity ^@ Belongs to the prokaryotic/mitochondrial release factor family. http://togogenome.org/gene/1144275:COCOR_RS05550 ^@ http://purl.uniprot.org/uniprot/H8MP75 ^@ Similarity ^@ Belongs to the UPF0051 (ycf24) family. http://togogenome.org/gene/1144275:COCOR_RS04040 ^@ http://purl.uniprot.org/uniprot/H8MIS0 ^@ Activity Regulation|||Caution|||Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.|||Belongs to the TPP enzyme family.|||Binds 1 FAD per subunit.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Cell inner membrane|||Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus. http://togogenome.org/gene/1144275:COCOR_RS13015 ^@ http://purl.uniprot.org/uniprot/H8MSE0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS10980 ^@ http://purl.uniprot.org/uniprot/H8MKF5 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS32385 ^@ http://purl.uniprot.org/uniprot/H8MT34 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS26685 ^@ http://purl.uniprot.org/uniprot/H8MW00 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling. http://togogenome.org/gene/1144275:COCOR_RS15595 ^@ http://purl.uniprot.org/uniprot/H8MF20 ^@ Similarity ^@ Belongs to the UDP-glycosyltransferase family. http://togogenome.org/gene/1144275:COCOR_RS13135 ^@ http://purl.uniprot.org/uniprot/H8MTU1 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion.|||Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.|||In the C-terminal section; belongs to the HTP reductase family.|||In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family. http://togogenome.org/gene/1144275:COCOR_RS18820 ^@ http://purl.uniprot.org/uniprot/H8MQZ5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS00890 ^@ http://purl.uniprot.org/uniprot/H8MV43 ^@ Cofactor|||PTM|||Subcellular Location Annotation ^@ Binds 2 heme groups per subunit.|||Binds 2 heme groups.|||Periplasm http://togogenome.org/gene/1144275:COCOR_RS32330 ^@ http://purl.uniprot.org/uniprot/H8MT23 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1144275:COCOR_RS31215 ^@ http://purl.uniprot.org/uniprot/H8MNW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS24960 ^@ http://purl.uniprot.org/uniprot/H8MPW8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the GcvP family.|||The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.|||The glycine cleavage system is composed of four proteins: P, T, L and H. http://togogenome.org/gene/1144275:COCOR_RS24810 ^@ http://purl.uniprot.org/uniprot/H8MNP2 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1144275:COCOR_RS17660 ^@ http://purl.uniprot.org/uniprot/H8MLW8 ^@ Function ^@ TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. http://togogenome.org/gene/1144275:COCOR_RS38495 ^@ http://purl.uniprot.org/uniprot/H8MT62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS03815 ^@ http://purl.uniprot.org/uniprot/H8MHI1 ^@ Function|||Similarity ^@ Belongs to the peptidase S46 family.|||Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. http://togogenome.org/gene/1144275:COCOR_RS18960 ^@ http://purl.uniprot.org/uniprot/H8MR21 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1144275:COCOR_RS13490 ^@ http://purl.uniprot.org/uniprot/H8MU08 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1. http://togogenome.org/gene/1144275:COCOR_RS05070 ^@ http://purl.uniprot.org/uniprot/H8MMS9 ^@ Caution|||Function|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. http://togogenome.org/gene/1144275:COCOR_RS21475 ^@ http://purl.uniprot.org/uniprot/H8N0K1 ^@ Similarity ^@ Belongs to the 5'(3')-deoxyribonucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS39325 ^@ http://purl.uniprot.org/uniprot/H8MWC9 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1144275:COCOR_RS21935 ^@ http://purl.uniprot.org/uniprot/H8N203 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1144275:COCOR_RS29505 ^@ http://purl.uniprot.org/uniprot/H8MIB8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS07120 ^@ http://purl.uniprot.org/uniprot/H8MV75 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS19795 ^@ http://purl.uniprot.org/uniprot/H8MU45 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS21660 ^@ http://purl.uniprot.org/uniprot/H8N1U7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.|||Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS24100 ^@ http://purl.uniprot.org/uniprot/H8MM47 ^@ Similarity ^@ Belongs to the ABC transporter superfamily. http://togogenome.org/gene/1144275:COCOR_RS33345 ^@ http://purl.uniprot.org/uniprot/H8MXQ8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 26 family. http://togogenome.org/gene/1144275:COCOR_RS16210 ^@ http://purl.uniprot.org/uniprot/H8MGI4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.|||Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS16530 ^@ http://purl.uniprot.org/uniprot/H8MHU7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1144275:COCOR_RS22430 ^@ http://purl.uniprot.org/uniprot/H8MGL3 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1144275:COCOR_RS11985 ^@ http://purl.uniprot.org/uniprot/H8MPF8 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. http://togogenome.org/gene/1144275:COCOR_RS25885 ^@ http://purl.uniprot.org/uniprot/H8MST7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 30 family. http://togogenome.org/gene/1144275:COCOR_RS34895 ^@ http://purl.uniprot.org/uniprot/H8MFQ8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS12230 ^@ http://purl.uniprot.org/uniprot/H8MPK6 ^@ Similarity ^@ Belongs to the adrenodoxin/putidaredoxin family. http://togogenome.org/gene/1144275:COCOR_RS15725 ^@ http://purl.uniprot.org/uniprot/H8MF46 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS38320 ^@ http://purl.uniprot.org/uniprot/H8MRU1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.|||Cytoplasm|||Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.|||Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel. http://togogenome.org/gene/1144275:COCOR_RS11260 ^@ http://purl.uniprot.org/uniprot/H8MLR3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS37570 ^@ http://purl.uniprot.org/uniprot/H8MP43 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS05690 ^@ http://purl.uniprot.org/uniprot/H8MPA4 ^@ Similarity|||Subunit ^@ Belongs to the threonine aldolase family.|||Homotetramer. http://togogenome.org/gene/1144275:COCOR_RS04825 ^@ http://purl.uniprot.org/uniprot/H8MLI1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1144275:COCOR_RS04965 ^@ http://purl.uniprot.org/uniprot/H8MLK9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS15250 ^@ http://purl.uniprot.org/uniprot/H8N1N4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1144275:COCOR_RS21430 ^@ http://purl.uniprot.org/uniprot/H8N0J1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS24680 ^@ http://purl.uniprot.org/uniprot/H8MNL6 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1144275:COCOR_RS11605 ^@ http://purl.uniprot.org/uniprot/H8MN29 ^@ Similarity ^@ Belongs to the threonine synthase family. http://togogenome.org/gene/1144275:COCOR_RS27615 ^@ http://purl.uniprot.org/uniprot/H8MZ96 ^@ Function|||Similarity ^@ Belongs to the RlpA family.|||Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. http://togogenome.org/gene/1144275:COCOR_RS09935 ^@ http://purl.uniprot.org/uniprot/H8MHK1 ^@ Domain|||Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.|||Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin. http://togogenome.org/gene/1144275:COCOR_RS28670 ^@ http://purl.uniprot.org/uniprot/H8MFL5 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the sirtuin family. Class II subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. http://togogenome.org/gene/1144275:COCOR_RS15145 ^@ http://purl.uniprot.org/uniprot/H8N1L3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1144275:COCOR_RS15230 ^@ http://purl.uniprot.org/uniprot/H8N1N0 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1144275:COCOR_RS25225 ^@ http://purl.uniprot.org/uniprot/H8MQ20 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS33245 ^@ http://purl.uniprot.org/uniprot/H8MWB0 ^@ Similarity ^@ Belongs to the glycosyl hydrolase family 6. http://togogenome.org/gene/1144275:COCOR_RS21090 ^@ http://purl.uniprot.org/uniprot/H8MYZ0 ^@ Similarity ^@ Belongs to the thioesterase family. http://togogenome.org/gene/1144275:COCOR_RS24045 ^@ http://purl.uniprot.org/uniprot/H8MM36 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. http://togogenome.org/gene/1144275:COCOR_RS22570 ^@ http://purl.uniprot.org/uniprot/H8MGP1 ^@ Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.|||Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2). http://togogenome.org/gene/1144275:COCOR_RS19880 ^@ http://purl.uniprot.org/uniprot/H8MU62 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1144275:COCOR_RS12565 ^@ http://purl.uniprot.org/uniprot/H8MQW9 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the prokaryotic/mitochondrial release factor family.|||Cytoplasm|||Methylated by PrmC. Methylation increases the termination efficiency of RF1.|||Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. http://togogenome.org/gene/1144275:COCOR_RS12130 ^@ http://purl.uniprot.org/uniprot/H8MPI7 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1144275:COCOR_RS14495 ^@ http://purl.uniprot.org/uniprot/H8MYP7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS02910 ^@ http://purl.uniprot.org/uniprot/H8MEQ2 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNase Z family.|||Binds 2 Zn(2+) ions.|||Homodimer.|||Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. http://togogenome.org/gene/1144275:COCOR_RS32210 ^@ http://purl.uniprot.org/uniprot/H8MSZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22650 ^@ http://purl.uniprot.org/uniprot/H8MGQ7 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1144275:COCOR_RS33050 ^@ http://purl.uniprot.org/uniprot/H8MW71 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS27620 ^@ http://purl.uniprot.org/uniprot/H8MZ97 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS22190 ^@ http://purl.uniprot.org/uniprot/H8MFC2 ^@ Caution|||Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS34905 ^@ http://purl.uniprot.org/uniprot/H8MFR1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS02620 ^@ http://purl.uniprot.org/uniprot/H8N1C5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS24465 ^@ http://purl.uniprot.org/uniprot/H8MNH0 ^@ Similarity ^@ Belongs to the cytochrome P450 family. http://togogenome.org/gene/1144275:COCOR_RS13115 ^@ http://purl.uniprot.org/uniprot/H8MTT7 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1144275:COCOR_RS31200 ^@ http://purl.uniprot.org/uniprot/H8MNW3 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS11500 ^@ http://purl.uniprot.org/uniprot/H8MN08 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bS21 family. http://togogenome.org/gene/1144275:COCOR_RS37560 ^@ http://purl.uniprot.org/uniprot/H8MP41 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1144275:COCOR_RS28035 ^@ http://purl.uniprot.org/uniprot/H8N222 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS35720 ^@ http://purl.uniprot.org/uniprot/H8MIG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TonB-dependent receptor family.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS12650 ^@ http://purl.uniprot.org/uniprot/H8MQY7 ^@ Similarity ^@ Belongs to the Nudix hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS14485 ^@ http://purl.uniprot.org/uniprot/H8MYP5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GHMP kinase family. GalK subfamily.|||Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS08310 ^@ http://purl.uniprot.org/uniprot/H8N002 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS15320 ^@ http://purl.uniprot.org/uniprot/H8N1P7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1144275:COCOR_RS10405 ^@ http://purl.uniprot.org/uniprot/H8MIY9 ^@ Cofactor|||Similarity ^@ Belongs to the UPF0313 family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. http://togogenome.org/gene/1144275:COCOR_RS32130 ^@ http://purl.uniprot.org/uniprot/H8MSY2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TatB family.|||Cell inner membrane|||Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.|||The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon. http://togogenome.org/gene/1144275:COCOR_RS12380 ^@ http://purl.uniprot.org/uniprot/H8MQT4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1144275:COCOR_RS13420 ^@ http://purl.uniprot.org/uniprot/H8MTZ9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1144275:COCOR_RS19125 ^@ http://purl.uniprot.org/uniprot/H8MR55 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS23470 ^@ http://purl.uniprot.org/uniprot/H8MJH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS39990 ^@ http://purl.uniprot.org/uniprot/H8MY42 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the heme-copper respiratory oxidase family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13500 ^@ http://purl.uniprot.org/uniprot/H8MU10 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1144275:COCOR_RS25100 ^@ http://purl.uniprot.org/uniprot/H8MPZ5 ^@ Caution|||Function|||Similarity ^@ Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.|||Catalyzes the NAD(+)-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS29715 ^@ http://purl.uniprot.org/uniprot/H8MJL4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30865 ^@ http://purl.uniprot.org/uniprot/H8MNP5 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS35415 ^@ http://purl.uniprot.org/uniprot/H8MH61 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1144275:COCOR_RS38515 ^@ http://purl.uniprot.org/uniprot/H8MT66 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS38920 ^@ http://purl.uniprot.org/uniprot/H8MUR8 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS08540 ^@ http://purl.uniprot.org/uniprot/H8N049 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS33045 ^@ http://purl.uniprot.org/uniprot/H8MW70 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytochrome c oxidase subunit 3 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS33685 ^@ http://purl.uniprot.org/uniprot/H8MZA8 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily. http://togogenome.org/gene/1144275:COCOR_RS11350 ^@ http://purl.uniprot.org/uniprot/H8MLT1 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1144275:COCOR_RS15515 ^@ http://purl.uniprot.org/uniprot/H8N1T5 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS32320 ^@ http://purl.uniprot.org/uniprot/H8MT21 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS27585 ^@ http://purl.uniprot.org/uniprot/H8MZ90 ^@ Similarity|||Subunit ^@ Belongs to the MoaE family.|||Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis. http://togogenome.org/gene/1144275:COCOR_RS28975 ^@ http://purl.uniprot.org/uniprot/H8MGX1 ^@ Similarity ^@ Belongs to the spermidine/spermine synthase family. http://togogenome.org/gene/1144275:COCOR_RS33890 ^@ http://purl.uniprot.org/uniprot/H8MZE9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS40440 ^@ http://purl.uniprot.org/uniprot/H8N144 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL34 family. http://togogenome.org/gene/1144275:COCOR_RS19695 ^@ http://purl.uniprot.org/uniprot/H8MU25 ^@ Similarity ^@ Belongs to the RecA family. http://togogenome.org/gene/1144275:COCOR_RS22445 ^@ http://purl.uniprot.org/uniprot/H8MGL6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1144275:COCOR_RS10640 ^@ http://purl.uniprot.org/uniprot/H8MJ35 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS27555 ^@ http://purl.uniprot.org/uniprot/H8MZ84 ^@ Caution|||Function|||PTM|||Similarity ^@ Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.|||Belongs to the ATP-dependent AMP-binding enzyme family.|||Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS24530 ^@ http://purl.uniprot.org/uniprot/H8MNI3 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS26915 ^@ http://purl.uniprot.org/uniprot/H8MXH1 ^@ Cofactor|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HMBS family.|||Binds 1 dipyrromethane group covalently.|||Monomer.|||Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.|||The porphobilinogen subunits are added to the dipyrromethane group. http://togogenome.org/gene/1144275:COCOR_RS33595 ^@ http://purl.uniprot.org/uniprot/H8MXV8 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the adenosylhomocysteinase family.|||Binds 1 NAD(+) per subunit.|||Cytoplasm|||May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. http://togogenome.org/gene/1144275:COCOR_RS35110 ^@ http://purl.uniprot.org/uniprot/H8MFV2 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS00245 ^@ http://purl.uniprot.org/uniprot/H8MTE2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS32135 ^@ http://purl.uniprot.org/uniprot/H8MSY3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS19760 ^@ http://purl.uniprot.org/uniprot/H8MU38 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DNA polymerase type-C family. DnaE2 subfamily.|||Cytoplasm|||DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. http://togogenome.org/gene/1144275:COCOR_RS31905 ^@ http://purl.uniprot.org/uniprot/H8MRK4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS15200 ^@ http://purl.uniprot.org/uniprot/H8N1M4 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uS19 family.|||Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. http://togogenome.org/gene/1144275:COCOR_RS35190 ^@ http://purl.uniprot.org/uniprot/H8MFW8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS26485 ^@ http://purl.uniprot.org/uniprot/H8MVW0 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1144275:COCOR_RS36135 ^@ http://purl.uniprot.org/uniprot/H8MJV3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell inner membrane|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1144275:COCOR_RS11045 ^@ http://purl.uniprot.org/uniprot/H8MKG8 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1144275:COCOR_RS04950 ^@ http://purl.uniprot.org/uniprot/H8MLK6 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS07935 ^@ http://purl.uniprot.org/uniprot/H8MYE4 ^@ Similarity ^@ Belongs to the cysteine synthase/cystathionine beta-synthase family. http://togogenome.org/gene/1144275:COCOR_RS06790 ^@ http://purl.uniprot.org/uniprot/H8MTN1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsY family.|||Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.|||Cell inner membrane|||Probably interacts with PlsX. http://togogenome.org/gene/1144275:COCOR_RS21200 ^@ http://purl.uniprot.org/uniprot/H8MZ14 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.|||Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.|||Cell inner membrane|||Cytoplasm|||Monomer. http://togogenome.org/gene/1144275:COCOR_RS11245 ^@ http://purl.uniprot.org/uniprot/H8MLR0 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS22465 ^@ http://purl.uniprot.org/uniprot/H8MGM0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NDK family.|||Cytoplasm|||Homotetramer.|||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. http://togogenome.org/gene/1144275:COCOR_RS32465 ^@ http://purl.uniprot.org/uniprot/H8MUH2 ^@ Similarity ^@ Belongs to the D-alanine--D-alanine ligase family. http://togogenome.org/gene/1144275:COCOR_RS31915 ^@ http://purl.uniprot.org/uniprot/H8MRK6 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Cu-Zn superoxide dismutase family.|||Binds 1 copper ion per subunit.|||Binds 1 zinc ion per subunit.|||Destroys radicals which are normally produced within the cells and which are toxic to biological systems. http://togogenome.org/gene/1144275:COCOR_RS06510 ^@ http://purl.uniprot.org/uniprot/H8MS50 ^@ Function|||Similarity ^@ Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.|||Belongs to the Fmt family. http://togogenome.org/gene/1144275:COCOR_RS03385 ^@ http://purl.uniprot.org/uniprot/H8MG45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS08270 ^@ http://purl.uniprot.org/uniprot/H8MZZ3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS09195 ^@ http://purl.uniprot.org/uniprot/H8MEV3 ^@ Subunit ^@ Interacts transiently with the RNA polymerase catalytic core formed by RpoA, RpoB, RpoC and RpoZ (2 alpha, 1 beta, 1 beta' and 1 omega subunit) to form the RNA polymerase holoenzyme that can initiate transcription. http://togogenome.org/gene/1144275:COCOR_RS39670 ^@ http://purl.uniprot.org/uniprot/H8MXX6 ^@ Function|||Similarity ^@ Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.|||Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs. http://togogenome.org/gene/1144275:COCOR_RS21690 ^@ http://purl.uniprot.org/uniprot/H8N1V3 ^@ Similarity ^@ Belongs to the GbsR family. http://togogenome.org/gene/1144275:COCOR_RS11015 ^@ http://purl.uniprot.org/uniprot/H8MKG2 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1144275:COCOR_RS12585 ^@ http://purl.uniprot.org/uniprot/H8MQX3 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1144275:COCOR_RS38805 ^@ http://purl.uniprot.org/uniprot/H8MTC2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS19635 ^@ http://purl.uniprot.org/uniprot/H8MU13 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homodimer or homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1144275:COCOR_RS38585 ^@ http://purl.uniprot.org/uniprot/H8MT79 ^@ Cofactor|||Similarity ^@ Belongs to the mandelate racemase/muconate lactonizing enzyme family.|||Binds 1 Mg(2+) ion per subunit. http://togogenome.org/gene/1144275:COCOR_RS15280 ^@ http://purl.uniprot.org/uniprot/H8N1P0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1144275:COCOR_RS13740 ^@ http://purl.uniprot.org/uniprot/H8MVI9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS31315 ^@ http://purl.uniprot.org/uniprot/H8MQ34 ^@ Function|||Subunit ^@ Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.|||This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. http://togogenome.org/gene/1144275:COCOR_RS30370 ^@ http://purl.uniprot.org/uniprot/H8ML45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS07760 ^@ http://purl.uniprot.org/uniprot/H8MWX7 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily. http://togogenome.org/gene/1144275:COCOR_RS20940 ^@ http://purl.uniprot.org/uniprot/H8MYW0 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1144275:COCOR_RS28220 ^@ http://purl.uniprot.org/uniprot/H8N259 ^@ Similarity ^@ In the C-terminal section; belongs to the transpeptidase family.|||In the N-terminal section; belongs to the glycosyltransferase 51 family. http://togogenome.org/gene/1144275:COCOR_RS35645 ^@ http://purl.uniprot.org/uniprot/H8MIF1 ^@ Subcellular Location Annotation ^@ Endoplasmic reticulum membrane|||Membrane http://togogenome.org/gene/1144275:COCOR_RS30060 ^@ http://purl.uniprot.org/uniprot/H8MKY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1144275:COCOR_RS37145 ^@ http://purl.uniprot.org/uniprot/H8MMQ6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS31415 ^@ http://purl.uniprot.org/uniprot/H8MQ54 ^@ Similarity ^@ Belongs to the GSP E family. http://togogenome.org/gene/1144275:COCOR_RS27570 ^@ http://purl.uniprot.org/uniprot/H8MZ87 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS38810 ^@ http://purl.uniprot.org/uniprot/H8MTC3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1144275:COCOR_RS13095 ^@ http://purl.uniprot.org/uniprot/H8MSF6 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1144275:COCOR_RS26440 ^@ http://purl.uniprot.org/uniprot/H8MUG9 ^@ Similarity ^@ Belongs to the heat shock protein 70 family. http://togogenome.org/gene/1144275:COCOR_RS27825 ^@ http://purl.uniprot.org/uniprot/H8N0S0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial secretin family. GSP D subfamily.|||Cell outer membrane http://togogenome.org/gene/1144275:COCOR_RS04115 ^@ http://purl.uniprot.org/uniprot/H8MIT5 ^@ Similarity ^@ Belongs to the thioesterase PaaI family. http://togogenome.org/gene/1144275:COCOR_RS27250 ^@ http://purl.uniprot.org/uniprot/H8MXN7 ^@ Similarity ^@ Belongs to the acyl coenzyme A hydrolase family. http://togogenome.org/gene/1144275:COCOR_RS02655 ^@ http://purl.uniprot.org/uniprot/H8MEK1 ^@ Similarity ^@ Belongs to the histone deacetylase family. http://togogenome.org/gene/1144275:COCOR_RS25690 ^@ http://purl.uniprot.org/uniprot/H8MSP8 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1144275:COCOR_RS15175 ^@ http://purl.uniprot.org/uniprot/H8MPU7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1144275:COCOR_RS32545 ^@ http://purl.uniprot.org/uniprot/H8MUI9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0719 family.|||Membrane http://togogenome.org/gene/1144275:COCOR_RS13380 ^@ http://purl.uniprot.org/uniprot/H8MTZ0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell inner membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1144275:COCOR_RS30075 ^@ http://purl.uniprot.org/uniprot/H8MKY9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1144275:COCOR_RS05090 ^@ http://purl.uniprot.org/uniprot/H8MMT3 ^@ Function ^@ Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP. http://togogenome.org/gene/1144275:COCOR_RS32815 ^@ http://purl.uniprot.org/uniprot/H8MUP4 ^@ Function|||Similarity ^@ Belongs to the alpha-ketoglutarate dehydrogenase family.|||E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). http://togogenome.org/gene/1144275:COCOR_RS05650 ^@ http://purl.uniprot.org/uniprot/H8MP95 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1144275:COCOR_RS12725 ^@ http://purl.uniprot.org/uniprot/H8MS87 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1144275:COCOR_RS33930 ^@ http://purl.uniprot.org/uniprot/H8MZF8 ^@ Similarity ^@ Belongs to the intradiol ring-cleavage dioxygenase family. http://togogenome.org/gene/1144275:COCOR_RS32340 ^@ http://purl.uniprot.org/uniprot/H8MT25 ^@ Function|||Similarity ^@ Belongs to the HPPK family.|||Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway. http://togogenome.org/gene/1144275:COCOR_RS19090 ^@ http://purl.uniprot.org/uniprot/H8MR47 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the uridine kinase family.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS10135 ^@ http://purl.uniprot.org/uniprot/H8MHN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1144275:COCOR_RS25180 ^@ http://purl.uniprot.org/uniprot/H8MQ11 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1144275:COCOR_RS15520 ^@ http://purl.uniprot.org/uniprot/H8N1T6 ^@ Similarity ^@ Belongs to the AHA1 family. http://togogenome.org/gene/1144275:COCOR_RS33280 ^@ http://purl.uniprot.org/uniprot/H8MXP4 ^@ Similarity ^@ Belongs to the YciI family. http://togogenome.org/gene/1144275:COCOR_RS38975 ^@ http://purl.uniprot.org/uniprot/H8MUS9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1144275:COCOR_RS00120 ^@ http://purl.uniprot.org/uniprot/H8MRY7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the DoxX family.|||Membrane