http://togogenome.org/gene/1045858:BINT_RS06630 ^@ http://purl.uniprot.org/uniprot/G0EP86 ^@ Function|||Similarity ^@ Belongs to the GTP-binding SRP family.|||Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum. http://togogenome.org/gene/1045858:BINT_RS13055 ^@ http://purl.uniprot.org/uniprot/G0EPI0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.|||Belongs to the KhpA RNA-binding protein family.|||Cytoplasm|||Forms a complex with KhpB. http://togogenome.org/gene/1045858:BINT_RS04305 ^@ http://purl.uniprot.org/uniprot/G0ELB4 ^@ Function|||Similarity ^@ Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.|||Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition. http://togogenome.org/gene/1045858:BINT_RS09930 ^@ http://purl.uniprot.org/uniprot/G0EKN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial flagellin family.|||Component of the core of the flagella.|||Periplasm|||Periplasmic flagellum http://togogenome.org/gene/1045858:BINT_RS00215 ^@ http://purl.uniprot.org/uniprot/G0EP06 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10335 ^@ http://purl.uniprot.org/uniprot/G0EL53 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS01430 ^@ http://purl.uniprot.org/uniprot/G0EHW4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12740 ^@ http://purl.uniprot.org/uniprot/G0ENV9 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1045858:BINT_RS11870 ^@ http://purl.uniprot.org/uniprot/G0EMX3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 35 family. http://togogenome.org/gene/1045858:BINT_RS02560 ^@ http://purl.uniprot.org/uniprot/G0EJF1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MreD family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01350 ^@ http://purl.uniprot.org/uniprot/G0EHU8 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL19 family.|||This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. http://togogenome.org/gene/1045858:BINT_RS09335 ^@ http://purl.uniprot.org/uniprot/G0EK39 ^@ Similarity ^@ Belongs to the 3-hydroxyacyl-CoA dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS05770 ^@ http://purl.uniprot.org/uniprot/G0EN20 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1045858:BINT_RS01575 ^@ http://purl.uniprot.org/uniprot/G0EHZ2 ^@ Similarity ^@ Belongs to the trans-sulfuration enzymes family. http://togogenome.org/gene/1045858:BINT_RS08140 ^@ http://purl.uniprot.org/uniprot/G0EIR5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. http://togogenome.org/gene/1045858:BINT_RS08215 ^@ http://purl.uniprot.org/uniprot/G0EIT2 ^@ Similarity ^@ Belongs to the metallophosphoesterase superfamily. YfcE family. http://togogenome.org/gene/1045858:BINT_RS11615 ^@ http://purl.uniprot.org/uniprot/G0EMS3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS13885 ^@ http://purl.uniprot.org/uniprot/G0EQW8 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.|||Belongs to the KdsB family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS04930 ^@ http://purl.uniprot.org/uniprot/G0EM45 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.|||Cell inner membrane|||Membrane|||Probable transporter of a GTP-driven Fe(2+) uptake system. http://togogenome.org/gene/1045858:BINT_RS08245 ^@ http://purl.uniprot.org/uniprot/G0EIT8 ^@ Function|||Similarity ^@ Belongs to the threonine synthase family.|||Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine. http://togogenome.org/gene/1045858:BINT_RS10185 ^@ http://purl.uniprot.org/uniprot/G0EL23 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bS18 family.|||Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6. http://togogenome.org/gene/1045858:BINT_RS01885 ^@ http://purl.uniprot.org/uniprot/G0EIL0 ^@ Function|||Subcellular Location Annotation|||Subunit ^@ Cytoplasm|||Heterodimer of HisH and HisF.|||IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. http://togogenome.org/gene/1045858:BINT_RS08490 ^@ http://purl.uniprot.org/uniprot/G0EJ65 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ExbD/TolR family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS04315 ^@ http://purl.uniprot.org/uniprot/G0ELB6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family.|||Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.|||Homotetramer. http://togogenome.org/gene/1045858:BINT_RS06175 ^@ http://purl.uniprot.org/uniprot/G0ENI4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS03510 ^@ http://purl.uniprot.org/uniprot/G0EKE9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the QueA family.|||Cytoplasm|||Monomer.|||Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). http://togogenome.org/gene/1045858:BINT_RS12960 ^@ http://purl.uniprot.org/uniprot/G0EPF8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 'phage' integrase family. XerC subfamily.|||Belongs to the 'phage' integrase family. XerD subfamily.|||Cytoplasm|||Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.|||Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. http://togogenome.org/gene/1045858:BINT_RS10665 ^@ http://purl.uniprot.org/uniprot/G0ELJ7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the GPI family.|||Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS02155 ^@ http://purl.uniprot.org/uniprot/G0EIZ3 ^@ Similarity ^@ Belongs to the MotB family. http://togogenome.org/gene/1045858:BINT_RS12450 ^@ http://purl.uniprot.org/uniprot/G0ENQ2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecY/SEC61-alpha family.|||Cell inner membrane|||Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. http://togogenome.org/gene/1045858:BINT_RS00225 ^@ http://purl.uniprot.org/uniprot/G0EP08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS02050 ^@ http://purl.uniprot.org/uniprot/G0EIX2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS08310 ^@ http://purl.uniprot.org/uniprot/G0EIV1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1045858:BINT_RS05900 ^@ http://purl.uniprot.org/uniprot/G0EN48 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12105 ^@ http://purl.uniprot.org/uniprot/G0ENA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FKBP-type PPIase family. Tig subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS03400 ^@ http://purl.uniprot.org/uniprot/G0EKC7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09100 ^@ http://purl.uniprot.org/uniprot/G0EJR1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10790 ^@ http://purl.uniprot.org/uniprot/G0ELU8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1045858:BINT_RS09920 ^@ http://purl.uniprot.org/uniprot/G0EKN7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS07945 ^@ http://purl.uniprot.org/uniprot/G0EI69 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS11855 ^@ http://purl.uniprot.org/uniprot/G0EMX0 ^@ Similarity ^@ Belongs to the iron-sulfur dependent L-serine dehydratase family. http://togogenome.org/gene/1045858:BINT_RS13760 ^@ http://purl.uniprot.org/uniprot/G0EQU3 ^@ Similarity ^@ Belongs to the 3-oxoacid CoA-transferase family. http://togogenome.org/gene/1045858:BINT_RS06185 ^@ http://purl.uniprot.org/uniprot/G0ENI6 ^@ Similarity ^@ Belongs to the aldehyde dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS13950 ^@ http://purl.uniprot.org/uniprot/G0EQY1 ^@ Similarity ^@ Belongs to the peptidase S41A family. http://togogenome.org/gene/1045858:BINT_RS06135 ^@ http://purl.uniprot.org/uniprot/G0ENH5 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/1045858:BINT_RS08420 ^@ http://purl.uniprot.org/uniprot/G0EJ51 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.|||Cytoplasm|||Homodimer.|||Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. http://togogenome.org/gene/1045858:BINT_RS12535 ^@ http://purl.uniprot.org/uniprot/G0ENR9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL2 family.|||One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome. http://togogenome.org/gene/1045858:BINT_RS01985 ^@ http://purl.uniprot.org/uniprot/G0EIN0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AIR synthase family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS11370 ^@ http://purl.uniprot.org/uniprot/G0EME2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS04595 ^@ http://purl.uniprot.org/uniprot/G0ELP7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.|||Homodimer.|||Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine. http://togogenome.org/gene/1045858:BINT_RS09130 ^@ http://purl.uniprot.org/uniprot/G0EJR7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS06855 ^@ http://purl.uniprot.org/uniprot/G0EPU2 ^@ Function|||Similarity ^@ Belongs to the MoeA family.|||Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. http://togogenome.org/gene/1045858:BINT_RS10895 ^@ http://purl.uniprot.org/uniprot/G0ELX1 ^@ Similarity ^@ Belongs to the peptidase S33 family. http://togogenome.org/gene/1045858:BINT_RS05310 ^@ http://purl.uniprot.org/uniprot/G0EMK0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FliD family.|||Homopentamer.|||Periplasm|||Periplasmic flagellum|||Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end. http://togogenome.org/gene/1045858:BINT_RS13770 ^@ http://purl.uniprot.org/uniprot/G0EQU5 ^@ Similarity ^@ Belongs to the polysaccharide synthase family. http://togogenome.org/gene/1045858:BINT_RS10370 ^@ http://purl.uniprot.org/uniprot/G0ELE0 ^@ Similarity ^@ Belongs to the ParB family. http://togogenome.org/gene/1045858:BINT_RS02980 ^@ http://purl.uniprot.org/uniprot/G0EJW1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsA/MreB family.|||Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.|||Cell inner membrane|||Self-interacts. Interacts with FtsZ. http://togogenome.org/gene/1045858:BINT_RS03290 ^@ http://purl.uniprot.org/uniprot/G0EKA5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09850 ^@ http://purl.uniprot.org/uniprot/G0EKM3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CoaE family.|||Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS06285 ^@ http://purl.uniprot.org/uniprot/G0ENK8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hemerythrin family.|||Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS02480 ^@ http://purl.uniprot.org/uniprot/G0EJD5 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS04995 ^@ http://purl.uniprot.org/uniprot/G0EM58 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the polypeptide deformylase family.|||Binds 1 Fe(2+) ion.|||Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. http://togogenome.org/gene/1045858:BINT_RS00830 ^@ http://purl.uniprot.org/uniprot/G0EQA0 ^@ Function|||Induction|||Similarity|||Subcellular Location Annotation|||Subunit ^@ ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.|||Belongs to the peptidase S16 family.|||By heat shock.|||Cytoplasm|||Homohexamer. Organized in a ring with a central cavity. http://togogenome.org/gene/1045858:BINT_RS12990 ^@ http://purl.uniprot.org/uniprot/G0EPG5 ^@ Caution|||Function|||Similarity ^@ Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor.|||Belongs to the biotin--protein ligase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS09965 ^@ http://purl.uniprot.org/uniprot/G0EKP6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS07390 ^@ http://purl.uniprot.org/uniprot/G0EQL3 ^@ Similarity ^@ Belongs to the glutamine synthetase family. http://togogenome.org/gene/1045858:BINT_RS05385 ^@ http://purl.uniprot.org/uniprot/G0EML5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glutamate 5-kinase family.|||Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS06225 ^@ http://purl.uniprot.org/uniprot/G0ENJ6 ^@ Similarity ^@ Belongs to the citrate synthase family. http://togogenome.org/gene/1045858:BINT_RS03860 ^@ http://purl.uniprot.org/uniprot/G0EKV0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1045858:BINT_RS05745 ^@ http://purl.uniprot.org/uniprot/G0EN15 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL9 family.|||Binds to the 23S rRNA. http://togogenome.org/gene/1045858:BINT_RS11580 ^@ http://purl.uniprot.org/uniprot/G0EMR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL1 family.|||Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.|||Part of the 50S ribosomal subunit.|||Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA. http://togogenome.org/gene/1045858:BINT_RS12010 ^@ http://purl.uniprot.org/uniprot/G0EN86 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family. http://togogenome.org/gene/1045858:BINT_RS07265 ^@ http://purl.uniprot.org/uniprot/G0EQI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12100 ^@ http://purl.uniprot.org/uniprot/G0ENA4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the peptidase S14 family.|||Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.|||Cytoplasm|||Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1045858:BINT_RS02130 ^@ http://purl.uniprot.org/uniprot/G0EIY8 ^@ Function|||PTM|||Similarity ^@ Belongs to the NAPRTase family.|||Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.|||Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release. http://togogenome.org/gene/1045858:BINT_RS06980 ^@ http://purl.uniprot.org/uniprot/G0EPW9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS12570 ^@ http://purl.uniprot.org/uniprot/G0ENS6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS7 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.|||Part of the 30S ribosomal subunit. Contacts proteins S9 and S11. http://togogenome.org/gene/1045858:BINT_RS02775 ^@ http://purl.uniprot.org/uniprot/G0EJI9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IspF family.|||Binds 1 divalent metal cation per subunit.|||Homotrimer.|||Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS14265 ^@ http://purl.uniprot.org/uniprot/G0EID0 ^@ Similarity|||Subunit ^@ Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS13325 ^@ http://purl.uniprot.org/uniprot/G0EQ45 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS08980 ^@ http://purl.uniprot.org/uniprot/G0EJN7 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1045858:BINT_RS04510 ^@ http://purl.uniprot.org/uniprot/G0ELN1 ^@ Function|||Similarity ^@ Belongs to the NusB family.|||Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. http://togogenome.org/gene/1045858:BINT_RS12980 ^@ http://purl.uniprot.org/uniprot/G0EPG3 ^@ Similarity ^@ Belongs to the small heat shock protein (HSP20) family. http://togogenome.org/gene/1045858:BINT_RS04680 ^@ http://purl.uniprot.org/uniprot/G0ELR5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferrochelatase family.|||Catalyzes the ferrous insertion into protoporphyrin IX.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS05305 ^@ http://purl.uniprot.org/uniprot/G0EMJ9 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS08795 ^@ http://purl.uniprot.org/uniprot/G0EJK1 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bL20 family.|||Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. http://togogenome.org/gene/1045858:BINT_RS01280 ^@ http://purl.uniprot.org/uniprot/G0EHT4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS07075 ^@ http://purl.uniprot.org/uniprot/G0EPZ0 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS04900 ^@ http://purl.uniprot.org/uniprot/G0EM39 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS03575 ^@ http://purl.uniprot.org/uniprot/G0EKG1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.|||This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. http://togogenome.org/gene/1045858:BINT_RS00895 ^@ http://purl.uniprot.org/uniprot/G0EQB4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS05315 ^@ http://purl.uniprot.org/uniprot/G0EMK1 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS08465 ^@ http://purl.uniprot.org/uniprot/G0EJ60 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the acetokinase family.|||Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.|||Cytoplasm|||Homodimer.|||Mg(2+). Can also accept Mn(2+). http://togogenome.org/gene/1045858:BINT_RS11290 ^@ http://purl.uniprot.org/uniprot/G0EMC6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SHMT family.|||Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS13845 ^@ http://purl.uniprot.org/uniprot/G0EQW0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the transcriptional regulatory Rex family.|||Cytoplasm|||Homodimer.|||Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. http://togogenome.org/gene/1045858:BINT_RS09125 ^@ http://purl.uniprot.org/uniprot/G0EJR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10060 ^@ http://purl.uniprot.org/uniprot/G0EKZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.|||Cytoplasm|||In the C-terminal section; belongs to the helicase family. RecG subfamily.|||In the N-terminal section; belongs to the UvrB family. http://togogenome.org/gene/1045858:BINT_RS13235 ^@ http://purl.uniprot.org/uniprot/G0EQ26 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS4 family.|||Membrane|||centrosome|||cilium membrane http://togogenome.org/gene/1045858:BINT_RS11325 ^@ http://purl.uniprot.org/uniprot/G0EMD3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS00200 ^@ http://purl.uniprot.org/uniprot/G0EP03 ^@ Function|||Miscellaneous|||Similarity|||Subunit ^@ A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.|||Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.|||Homodimer.|||Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. http://togogenome.org/gene/1045858:BINT_RS09670 ^@ http://purl.uniprot.org/uniprot/G0EKI6 ^@ Similarity ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. http://togogenome.org/gene/1045858:BINT_RS06470 ^@ http://purl.uniprot.org/uniprot/G0EP54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS12060 ^@ http://purl.uniprot.org/uniprot/G0EN96 ^@ Similarity ^@ In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family. http://togogenome.org/gene/1045858:BINT_RS07710 ^@ http://purl.uniprot.org/uniprot/G0EI24 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NusA family.|||Cytoplasm|||Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.|||Participates in both transcription termination and antitermination. http://togogenome.org/gene/1045858:BINT_RS08910 ^@ http://purl.uniprot.org/uniprot/G0EJM3 ^@ Similarity ^@ Belongs to the helicase family. RAD25/XPB subfamily. http://togogenome.org/gene/1045858:BINT_RS00580 ^@ http://purl.uniprot.org/uniprot/G0EPP3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS03025 ^@ http://purl.uniprot.org/uniprot/G0EJX0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the triosephosphate isomerase family.|||Cytoplasm|||Homodimer.|||Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P). http://togogenome.org/gene/1045858:BINT_RS01345 ^@ http://purl.uniprot.org/uniprot/G0EHU7 ^@ Cofactor ^@ Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1045858:BINT_RS03300 ^@ http://purl.uniprot.org/uniprot/G0EKA7 ^@ Similarity ^@ Belongs to the PEP-utilizing enzyme family. http://togogenome.org/gene/1045858:BINT_RS05415 ^@ http://purl.uniprot.org/uniprot/G0EMM1 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS11955 ^@ http://purl.uniprot.org/uniprot/G0EN74 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0718 family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS03985 ^@ http://purl.uniprot.org/uniprot/G0EKX3 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS09290 ^@ http://purl.uniprot.org/uniprot/G0EK30 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1045858:BINT_RS08275 ^@ http://purl.uniprot.org/uniprot/G0EIU4 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the type-II 3-dehydroquinase family.|||Catalyzes a trans-dehydration via an enolate intermediate.|||Homododecamer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS04540 ^@ http://purl.uniprot.org/uniprot/G0ELN7 ^@ Function|||Similarity ^@ Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.|||Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). http://togogenome.org/gene/1045858:BINT_RS05775 ^@ http://purl.uniprot.org/uniprot/G0EN21 ^@ Similarity ^@ Belongs to the UPF0234 family. http://togogenome.org/gene/1045858:BINT_RS09905 ^@ http://purl.uniprot.org/uniprot/G0EKN4 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.|||Binds 3 [4Fe-4S] clusters.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1045858:BINT_RS11590 ^@ http://purl.uniprot.org/uniprot/G0EMR9 ^@ Function|||Similarity ^@ Belongs to the NusG family.|||Participates in transcription elongation, termination and antitermination. http://togogenome.org/gene/1045858:BINT_RS02655 ^@ http://purl.uniprot.org/uniprot/G0EJG6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS13005 ^@ http://purl.uniprot.org/uniprot/G0EPG8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.|||Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS04755 ^@ http://purl.uniprot.org/uniprot/G0ELT1 ^@ Function|||Similarity ^@ Belongs to the RecR family.|||May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. http://togogenome.org/gene/1045858:BINT_RS12455 ^@ http://purl.uniprot.org/uniprot/G0ENQ3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL15 family.|||Binds to the 23S rRNA.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS02500 ^@ http://purl.uniprot.org/uniprot/G0EJD9 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1045858:BINT_RS13420 ^@ http://purl.uniprot.org/uniprot/G0EQ64 ^@ Function|||Similarity ^@ Belongs to the NAD-dependent DNA ligase family. LigA subfamily.|||DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. http://togogenome.org/gene/1045858:BINT_RS00700 ^@ http://purl.uniprot.org/uniprot/G0EPR6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS07380 ^@ http://purl.uniprot.org/uniprot/G0EQL1 ^@ Domain|||Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CheB family.|||Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.|||Cytoplasm|||Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.|||Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity. http://togogenome.org/gene/1045858:BINT_RS12970 ^@ http://purl.uniprot.org/uniprot/G0EPG0 ^@ Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS12460 ^@ http://purl.uniprot.org/uniprot/G0ENQ4 ^@ Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL30 family.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS04075 ^@ http://purl.uniprot.org/uniprot/G0EL70 ^@ Function|||Similarity ^@ Belongs to the chloramphenicol acetyltransferase family.|||This enzyme is an effector of chloramphenicol resistance in bacteria. http://togogenome.org/gene/1045858:BINT_RS09915 ^@ http://purl.uniprot.org/uniprot/G0EKN6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1045858:BINT_RS06680 ^@ http://purl.uniprot.org/uniprot/G0EP97 ^@ Function ^@ Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. http://togogenome.org/gene/1045858:BINT_RS11180 ^@ http://purl.uniprot.org/uniprot/G0EMA4 ^@ Similarity|||Subunit ^@ Belongs to the CarA family.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate. http://togogenome.org/gene/1045858:BINT_RS01930 ^@ http://purl.uniprot.org/uniprot/G0EIL9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the bacterial flagellin family.|||Component of the core of the flagella.|||Periplasm|||Periplasmic flagellum http://togogenome.org/gene/1045858:BINT_RS01540 ^@ http://purl.uniprot.org/uniprot/G0EHY5 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the RuvC family.|||Binds 1 Mg(2+) ion per subunit.|||Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. http://togogenome.org/gene/1045858:BINT_RS01085 ^@ http://purl.uniprot.org/uniprot/G0EQF3 ^@ Similarity ^@ Belongs to the PHP hydrolase family. HisK subfamily. http://togogenome.org/gene/1045858:BINT_RS04000 ^@ http://purl.uniprot.org/uniprot/G0EKX6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurJ/MviN family.|||Cell inner membrane|||Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.|||Membrane http://togogenome.org/gene/1045858:BINT_RS03035 ^@ http://purl.uniprot.org/uniprot/G0EJX2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the Nth/MutY family.|||Binds 1 [4Fe-4S] cluster.|||DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate. http://togogenome.org/gene/1045858:BINT_RS05455 ^@ http://purl.uniprot.org/uniprot/G0EMM9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).|||Cytoplasm|||Monomer. http://togogenome.org/gene/1045858:BINT_RS13195 ^@ http://purl.uniprot.org/uniprot/G0EQ19 ^@ Function|||Similarity ^@ Belongs to the vsr family.|||May nick specific sequences that contain T:G mispairs resulting from m5C-deamination. http://togogenome.org/gene/1045858:BINT_RS01165 ^@ http://purl.uniprot.org/uniprot/G0EQG9 ^@ Similarity ^@ Belongs to the RecJ family. http://togogenome.org/gene/1045858:BINT_RS00850 ^@ http://purl.uniprot.org/uniprot/G0EQA4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS02335 ^@ http://purl.uniprot.org/uniprot/G0EJ27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecD subfamily.|||Cell inner membrane|||Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1045858:BINT_RS13245 ^@ http://purl.uniprot.org/uniprot/G0EQ29 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS20 family.|||Binds directly to 16S ribosomal RNA. http://togogenome.org/gene/1045858:BINT_RS01370 ^@ http://purl.uniprot.org/uniprot/G0EHV2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS11225 ^@ http://purl.uniprot.org/uniprot/G0EMB3 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the HAM1 NTPase family.|||Binds 1 Mg(2+) ion per subunit.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. http://togogenome.org/gene/1045858:BINT_RS00135 ^@ http://purl.uniprot.org/uniprot/G0ENZ0 ^@ Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily. http://togogenome.org/gene/1045858:BINT_RS11705 ^@ http://purl.uniprot.org/uniprot/G0EMU1 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/1045858:BINT_RS04830 ^@ http://purl.uniprot.org/uniprot/G0EM27 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1045858:BINT_RS05620 ^@ http://purl.uniprot.org/uniprot/G0EMR1 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1045858:BINT_RS06280 ^@ http://purl.uniprot.org/uniprot/G0ENK7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the hemerythrin family.|||Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS04470 ^@ http://purl.uniprot.org/uniprot/G0ELM6 ^@ Similarity ^@ Belongs to the pyruvate kinase family. http://togogenome.org/gene/1045858:BINT_RS12365 ^@ http://purl.uniprot.org/uniprot/G0ENN6 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||Allosterically activated by HslU binding.|||Belongs to the peptidase T1B family. HslV subfamily.|||Cytoplasm|||Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. http://togogenome.org/gene/1045858:BINT_RS14220 ^@ http://purl.uniprot.org/uniprot/G0EIC1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the PlsX family.|||Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.|||Cytoplasm|||Homodimer. Probably interacts with PlsY. http://togogenome.org/gene/1045858:BINT_RS11040 ^@ http://purl.uniprot.org/uniprot/G0ELZ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the shikimate kinase family.|||Binds 1 Mg(2+) ion per subunit.|||Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS02815 ^@ http://purl.uniprot.org/uniprot/G0EJS7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the queuine tRNA-ribosyltransferase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).|||Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS08385 ^@ http://purl.uniprot.org/uniprot/G0EJ44 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS12360 ^@ http://purl.uniprot.org/uniprot/G0ENN5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.|||ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.|||Belongs to the ClpX chaperone family. HslU subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS09835 ^@ http://purl.uniprot.org/uniprot/G0EKM0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS09275 ^@ http://purl.uniprot.org/uniprot/G0EK27 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrC family.|||Cytoplasm|||Interacts with UvrB in an incision complex.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. http://togogenome.org/gene/1045858:BINT_RS06170 ^@ http://purl.uniprot.org/uniprot/G0ENI3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10240 ^@ http://purl.uniprot.org/uniprot/G0EL35 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the aconitase/IPM isomerase family. LeuC type 2 subfamily.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.|||Heterodimer of LeuC and LeuD. http://togogenome.org/gene/1045858:BINT_RS02165 ^@ http://purl.uniprot.org/uniprot/G0EIZ5 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1045858:BINT_RS12250 ^@ http://purl.uniprot.org/uniprot/G0END3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase C chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01660 ^@ http://purl.uniprot.org/uniprot/G0EIG5 ^@ Similarity ^@ Belongs to the UPF0164 family. http://togogenome.org/gene/1045858:BINT_RS01825 ^@ http://purl.uniprot.org/uniprot/G0EIJ8 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.|||Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS01845 ^@ http://purl.uniprot.org/uniprot/G0EIK2 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1045858:BINT_RS02760 ^@ http://purl.uniprot.org/uniprot/G0EJI5 ^@ Similarity ^@ Belongs to the GARS family. http://togogenome.org/gene/1045858:BINT_RS03465 ^@ http://purl.uniprot.org/uniprot/G0EKE0 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1045858:BINT_RS13910 ^@ http://purl.uniprot.org/uniprot/G0EQX3 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 1 family. http://togogenome.org/gene/1045858:BINT_RS08540 ^@ http://purl.uniprot.org/uniprot/G0EJ74 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.|||Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS00995 ^@ http://purl.uniprot.org/uniprot/G0EQD4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12645 ^@ http://purl.uniprot.org/uniprot/G0ENU1 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS10190 ^@ http://purl.uniprot.org/uniprot/G0EL24 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS03615 ^@ http://purl.uniprot.org/uniprot/G0EKP9 ^@ Cofactor|||Similarity ^@ Belongs to the complex I 24 kDa subunit family.|||Binds 1 [2Fe-2S] cluster. http://togogenome.org/gene/1045858:BINT_RS05100 ^@ http://purl.uniprot.org/uniprot/G0EM77 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 28 family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09285 ^@ http://purl.uniprot.org/uniprot/G0EK29 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.|||Binds 2 magnesium ions per tetramer.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1045858:BINT_RS10535 ^@ http://purl.uniprot.org/uniprot/G0ELH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the Iojap/RsfS family.|||Cytoplasm|||Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.|||Interacts with ribosomal protein L14 (rplN). http://togogenome.org/gene/1045858:BINT_RS08415 ^@ http://purl.uniprot.org/uniprot/G0EJ50 ^@ Similarity ^@ Belongs to the fabD family. http://togogenome.org/gene/1045858:BINT_RS07905 ^@ http://purl.uniprot.org/uniprot/G0EI61 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS05805 ^@ http://purl.uniprot.org/uniprot/G0EN27 ^@ Similarity|||Subunit ^@ Belongs to the RNase H family.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS02175 ^@ http://purl.uniprot.org/uniprot/G0EIZ7 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A monovalent cation. Ammonium or potassium.|||Belongs to the type III pantothenate kinase family.|||Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS09735 ^@ http://purl.uniprot.org/uniprot/G0EKJ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS11770 ^@ http://purl.uniprot.org/uniprot/G0EMV4 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1045858:BINT_RS06710 ^@ http://purl.uniprot.org/uniprot/G0EPA3 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UvrB family.|||Cytoplasm|||Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.|||The beta-hairpin motif is involved in DNA binding. http://togogenome.org/gene/1045858:BINT_RS03125 ^@ http://purl.uniprot.org/uniprot/G0EJZ2 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspH family.|||Binds 1 [4Fe-4S] cluster per subunit.|||Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. http://togogenome.org/gene/1045858:BINT_RS12550 ^@ http://purl.uniprot.org/uniprot/G0ENS2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL3 family.|||One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19. http://togogenome.org/gene/1045858:BINT_RS08280 ^@ http://purl.uniprot.org/uniprot/G0EIU5 ^@ Similarity ^@ Belongs to the peptidase M24B family. http://togogenome.org/gene/1045858:BINT_RS05755 ^@ http://purl.uniprot.org/uniprot/G0EN17 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MlaE permease family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01470 ^@ http://purl.uniprot.org/uniprot/G0EHX2 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/1045858:BINT_RS11045 ^@ http://purl.uniprot.org/uniprot/G0EM00 ^@ Function|||Subcellular Location Annotation ^@ Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS12710 ^@ http://purl.uniprot.org/uniprot/G0ENV3 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1045858:BINT_RS03555 ^@ http://purl.uniprot.org/uniprot/G0EKF8 ^@ Similarity ^@ Belongs to the eIF-2B alpha/beta/delta subunits family. http://togogenome.org/gene/1045858:BINT_RS13485 ^@ http://purl.uniprot.org/uniprot/G0EQ76 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS07050 ^@ http://purl.uniprot.org/uniprot/G0EPY5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0073 (Hly-III) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS11710 ^@ http://purl.uniprot.org/uniprot/G0EMU2 ^@ Similarity ^@ Belongs to the Fur family. http://togogenome.org/gene/1045858:BINT_RS12095 ^@ http://purl.uniprot.org/uniprot/G0ENA3 ^@ Function|||Similarity|||Subunit ^@ ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.|||Belongs to the ClpX chaperone family.|||Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes. http://togogenome.org/gene/1045858:BINT_RS05170 ^@ http://purl.uniprot.org/uniprot/G0EM91 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the metallo-dependent hydrolases superfamily. HutI family.|||Binds 1 zinc or iron ion per subunit.|||Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS13445 ^@ http://purl.uniprot.org/uniprot/G0EQ68 ^@ Similarity ^@ Belongs to the peptidase C56 family. http://togogenome.org/gene/1045858:BINT_RS01595 ^@ http://purl.uniprot.org/uniprot/G0EIF1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the thiamine-phosphate synthase family.|||Binds 1 Mg(2+) ion per subunit.|||Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). http://togogenome.org/gene/1045858:BINT_RS11875 ^@ http://purl.uniprot.org/uniprot/G0EMX4 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.|||Monomer.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1045858:BINT_RS10695 ^@ http://purl.uniprot.org/uniprot/G0ELK3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS06800 ^@ http://purl.uniprot.org/uniprot/G0EPC1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10430 ^@ http://purl.uniprot.org/uniprot/G0ELF2 ^@ Function|||Similarity ^@ ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.|||Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily. http://togogenome.org/gene/1045858:BINT_RS09410 ^@ http://purl.uniprot.org/uniprot/G0EK54 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RsmH family.|||Cytoplasm|||Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. http://togogenome.org/gene/1045858:BINT_RS07825 ^@ http://purl.uniprot.org/uniprot/G0EI47 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10255 ^@ http://purl.uniprot.org/uniprot/G0EL38 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Belongs to the ketol-acid reductoisomerase family.|||Binds 2 magnesium ions per subunit.|||Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS01860 ^@ http://purl.uniprot.org/uniprot/G0EIK5 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M17 family.|||Binds 2 manganese ions per subunit.|||Cytoplasm|||Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides. http://togogenome.org/gene/1045858:BINT_RS10800 ^@ http://purl.uniprot.org/uniprot/G0ELV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the encapsulin family. Family 1 subfamily.|||Encapsulin nanocompartment http://togogenome.org/gene/1045858:BINT_RS05905 ^@ http://purl.uniprot.org/uniprot/G0EN49 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DnaA family.|||Cytoplasm|||Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. http://togogenome.org/gene/1045858:BINT_RS10760 ^@ http://purl.uniprot.org/uniprot/G0ELL4 ^@ Similarity ^@ Belongs to the SAICAR synthetase family. http://togogenome.org/gene/1045858:BINT_RS13730 ^@ http://purl.uniprot.org/uniprot/G0EQT7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS06190 ^@ http://purl.uniprot.org/uniprot/G0ENI7 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1045858:BINT_RS02505 ^@ http://purl.uniprot.org/uniprot/G0EJE0 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1045858:BINT_RS13120 ^@ http://purl.uniprot.org/uniprot/G0EPJ2 ^@ Similarity ^@ Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. http://togogenome.org/gene/1045858:BINT_RS02330 ^@ http://purl.uniprot.org/uniprot/G0EJ26 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecD/SecF family. SecF subfamily.|||Cell inner membrane|||Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Membrane|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. http://togogenome.org/gene/1045858:BINT_RS04045 ^@ http://purl.uniprot.org/uniprot/G0EL65 ^@ Similarity ^@ Belongs to the DprA/Smf family. http://togogenome.org/gene/1045858:BINT_RS03350 ^@ http://purl.uniprot.org/uniprot/G0EKB7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the type-I 3-dehydroquinase family.|||Homodimer.|||Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. http://togogenome.org/gene/1045858:BINT_RS06010 ^@ http://purl.uniprot.org/uniprot/G0EN70 ^@ Similarity ^@ Belongs to the TlyA family. http://togogenome.org/gene/1045858:BINT_RS06785 ^@ http://purl.uniprot.org/uniprot/G0EPB8 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS08815 ^@ http://purl.uniprot.org/uniprot/G0EJK5 ^@ Cofactor ^@ Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution. http://togogenome.org/gene/1045858:BINT_RS04210 ^@ http://purl.uniprot.org/uniprot/G0EL97 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the PEP-utilizing enzyme family.|||Cytoplasm|||General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). http://togogenome.org/gene/1045858:BINT_RS10835 ^@ http://purl.uniprot.org/uniprot/G0ELV7 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the IspG family.|||Binds 1 [4Fe-4S] cluster.|||Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. http://togogenome.org/gene/1045858:BINT_RS13305 ^@ http://purl.uniprot.org/uniprot/G0EQ41 ^@ Function|||Similarity ^@ Belongs to the FlgD family.|||Required for flagellar hook formation. May act as a scaffolding protein. http://togogenome.org/gene/1045858:BINT_RS02000 ^@ http://purl.uniprot.org/uniprot/G0EIW4 ^@ Similarity ^@ Belongs to the sigma-70 factor family. ECF subfamily. http://togogenome.org/gene/1045858:BINT_RS09545 ^@ http://purl.uniprot.org/uniprot/G0EK81 ^@ Similarity ^@ Belongs to the xanthine dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS09690 ^@ http://purl.uniprot.org/uniprot/G0EKJ0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the ABC-3 integral membrane protein family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS10035 ^@ http://purl.uniprot.org/uniprot/G0EKZ0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the topoisomerase GyrA/ParC subunit family.|||Belongs to the type II topoisomerase GyrA/ParC subunit family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1045858:BINT_RS08670 ^@ http://purl.uniprot.org/uniprot/G0EJ97 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.|||Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS12375 ^@ http://purl.uniprot.org/uniprot/G0ENN8 ^@ Similarity ^@ Belongs to the iron-containing alcohol dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS06445 ^@ http://purl.uniprot.org/uniprot/G0EP49 ^@ Similarity ^@ Belongs to the phosphate acetyltransferase and butyryltransferase family. http://togogenome.org/gene/1045858:BINT_RS07070 ^@ http://purl.uniprot.org/uniprot/G0EPY9 ^@ Function|||Similarity ^@ Belongs to the transglycosylase MltG family.|||Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. http://togogenome.org/gene/1045858:BINT_RS06690 ^@ http://purl.uniprot.org/uniprot/G0EP99 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SelA family.|||Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS12555 ^@ http://purl.uniprot.org/uniprot/G0ENS3 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS10 family.|||Involved in the binding of tRNA to the ribosomes.|||Part of the 30S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS05075 ^@ http://purl.uniprot.org/uniprot/G0EM72 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1045858:BINT_RS06110 ^@ http://purl.uniprot.org/uniprot/G0ENH0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ClpA/ClpB family.|||Cytoplasm|||Homohexamer. The oligomerization is ATP-dependent.|||Homohexamer; The oligomerization is ATP-dependent.|||Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. http://togogenome.org/gene/1045858:BINT_RS14190 ^@ http://purl.uniprot.org/uniprot/G0EIB5 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1045858:BINT_RS03940 ^@ http://purl.uniprot.org/uniprot/G0EKW6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS09790 ^@ http://purl.uniprot.org/uniprot/G0EKL0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.|||Belongs to the FliW family.|||Cytoplasm|||Interacts with translational regulator CsrA and flagellin(s). http://togogenome.org/gene/1045858:BINT_RS12525 ^@ http://purl.uniprot.org/uniprot/G0ENR7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL22 family.|||Part of the 50S ribosomal subunit.|||The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. http://togogenome.org/gene/1045858:BINT_RS04460 ^@ http://purl.uniprot.org/uniprot/G0ELM4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.|||Cytoplasm|||Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. http://togogenome.org/gene/1045858:BINT_RS05795 ^@ http://purl.uniprot.org/uniprot/G0EN25 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RbfA family.|||Cytoplasm|||Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. http://togogenome.org/gene/1045858:BINT_RS10220 ^@ http://purl.uniprot.org/uniprot/G0EL31 ^@ Similarity ^@ Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family. http://togogenome.org/gene/1045858:BINT_RS04620 ^@ http://purl.uniprot.org/uniprot/G0ELQ2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvA family.|||Forms a complex with RuvB.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. http://togogenome.org/gene/1045858:BINT_RS01900 ^@ http://purl.uniprot.org/uniprot/G0EIL3 ^@ Similarity ^@ Belongs to the glycerate kinase type-1 family. http://togogenome.org/gene/1045858:BINT_RS08325 ^@ http://purl.uniprot.org/uniprot/G0EIV4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS05220 ^@ http://purl.uniprot.org/uniprot/G0EMA1 ^@ Caution|||Cofactor|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Belongs to the radical SAM superfamily. RlmN family.|||Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.|||Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. http://togogenome.org/gene/1045858:BINT_RS10260 ^@ http://purl.uniprot.org/uniprot/G0EL39 ^@ Function|||Similarity|||Subunit ^@ Belongs to the acetolactate synthase small subunit family.|||Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.|||Dimer of large and small chains. http://togogenome.org/gene/1045858:BINT_RS05200 ^@ http://purl.uniprot.org/uniprot/G0EM97 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the EPSP synthase family.|||Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS02945 ^@ http://purl.uniprot.org/uniprot/G0EJV4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the beta sliding clamp family.|||Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.|||Cytoplasm|||Forms a ring-shaped head-to-tail homodimer around DNA. http://togogenome.org/gene/1045858:BINT_RS05490 ^@ http://purl.uniprot.org/uniprot/G0EMN6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliG family.|||Cell inner membrane|||FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09610 ^@ http://purl.uniprot.org/uniprot/G0EKH4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS04845 ^@ http://purl.uniprot.org/uniprot/G0EM30 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the tRNA pseudouridine synthase TruA family.|||Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS13530 ^@ http://purl.uniprot.org/uniprot/G0EQ85 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS12240 ^@ http://purl.uniprot.org/uniprot/G0END1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1045858:BINT_RS09795 ^@ http://purl.uniprot.org/uniprot/G0EKL1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.|||Belongs to the CsrA/RsmA family.|||Cytoplasm|||Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core. http://togogenome.org/gene/1045858:BINT_RS06050 ^@ http://purl.uniprot.org/uniprot/G0ENF8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS10230 ^@ http://purl.uniprot.org/uniprot/G0EL33 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.|||Binds 1 Mg(2+) or Mn(2+) ion per subunit.|||Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS10715 ^@ http://purl.uniprot.org/uniprot/G0ELK7 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 57 family. http://togogenome.org/gene/1045858:BINT_RS03670 ^@ http://purl.uniprot.org/uniprot/G0EKR0 ^@ Function|||Subcellular Location Annotation ^@ Membrane|||The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. http://togogenome.org/gene/1045858:BINT_RS08365 ^@ http://purl.uniprot.org/uniprot/G0EJ40 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the UPP synthase family.|||Binds 2 magnesium ions per subunit.|||Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS12410 ^@ http://purl.uniprot.org/uniprot/G0ENP5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the Rho family.|||Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.|||Homohexamer. The homohexamer assembles into an open ring structure.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS05015 ^@ http://purl.uniprot.org/uniprot/G0EM62 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1045858:BINT_RS09910 ^@ http://purl.uniprot.org/uniprot/G0EKN5 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the NqrDE/RnfAE family.|||Cell inner membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1045858:BINT_RS08695 ^@ http://purl.uniprot.org/uniprot/G0EJA2 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1045858:BINT_RS10330 ^@ http://purl.uniprot.org/uniprot/G0EL52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS02360 ^@ http://purl.uniprot.org/uniprot/G0EJ31 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS03840 ^@ http://purl.uniprot.org/uniprot/G0EKU6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10325 ^@ http://purl.uniprot.org/uniprot/G0EL51 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.|||Binds 1 zinc ion per subunit.|||Cytoplasm|||Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.|||One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS01465 ^@ http://purl.uniprot.org/uniprot/G0EHX1 ^@ Similarity ^@ Belongs to the PNP/UDP phosphorylase family. http://togogenome.org/gene/1045858:BINT_RS07145 ^@ http://purl.uniprot.org/uniprot/G0EQ04 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1045858:BINT_RS10690 ^@ http://purl.uniprot.org/uniprot/G0ELK2 ^@ Cofactor|||Similarity ^@ Belongs to the glycosyl hydrolase 4 family.|||Binds 1 NAD(+) per subunit. http://togogenome.org/gene/1045858:BINT_RS00220 ^@ http://purl.uniprot.org/uniprot/G0EP07 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS01905 ^@ http://purl.uniprot.org/uniprot/G0EIL4 ^@ Similarity ^@ Belongs to the CdaR family. http://togogenome.org/gene/1045858:BINT_RS10455 ^@ http://purl.uniprot.org/uniprot/G0ELF7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS15 family.|||Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.|||Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA. http://togogenome.org/gene/1045858:BINT_RS08840 ^@ http://purl.uniprot.org/uniprot/G0EJL0 ^@ Function|||Subcellular Location Annotation ^@ Cytoplasm|||Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein. http://togogenome.org/gene/1045858:BINT_RS00235 ^@ http://purl.uniprot.org/uniprot/G0EP10 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1045858:BINT_RS13020 ^@ http://purl.uniprot.org/uniprot/G0EPH2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS00920 ^@ http://purl.uniprot.org/uniprot/G0EQB9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase 4 family. MraY subfamily.|||Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS10515 ^@ http://purl.uniprot.org/uniprot/G0ELG8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecA family.|||Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS06220 ^@ http://purl.uniprot.org/uniprot/G0ENJ5 ^@ Similarity ^@ Belongs to the HAD-like hydrolase superfamily. SerB family. http://togogenome.org/gene/1045858:BINT_RS04115 ^@ http://purl.uniprot.org/uniprot/G0EL78 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the OMP decarboxylase family. Type 1 subfamily.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.|||Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).|||Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).|||Homodimer.|||In the C-terminal section; belongs to the OMP decarboxylase family.|||In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS06915 ^@ http://purl.uniprot.org/uniprot/G0EPV4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.|||Belongs to the EF-Ts family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS13810 ^@ http://purl.uniprot.org/uniprot/G0EQV3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MgtC/SapB family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS13070 ^@ http://purl.uniprot.org/uniprot/G0EPI3 ^@ Similarity ^@ Belongs to the peptidase M16 family. http://togogenome.org/gene/1045858:BINT_RS08505 ^@ http://purl.uniprot.org/uniprot/G0EJ67 ^@ Function|||Similarity ^@ Belongs to the dTDP-4-dehydrorhamnose reductase family.|||Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. http://togogenome.org/gene/1045858:BINT_RS03855 ^@ http://purl.uniprot.org/uniprot/G0EKU9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial solute-binding protein 2 family.|||Periplasm|||The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB). http://togogenome.org/gene/1045858:BINT_RS13065 ^@ http://purl.uniprot.org/uniprot/G0EPI2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GTP-binding SRP family. SRP54 subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS07000 ^@ http://purl.uniprot.org/uniprot/G0EPX3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS12470 ^@ http://purl.uniprot.org/uniprot/G0ENQ6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL18 family.|||Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.|||This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. http://togogenome.org/gene/1045858:BINT_RS01645 ^@ http://purl.uniprot.org/uniprot/G0EIG2 ^@ Similarity ^@ Belongs to the peptidase S66 family. http://togogenome.org/gene/1045858:BINT_RS14180 ^@ http://purl.uniprot.org/uniprot/G0EIB3 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1045858:BINT_RS12345 ^@ http://purl.uniprot.org/uniprot/G0ENF2 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS09385 ^@ http://purl.uniprot.org/uniprot/G0EK49 ^@ Similarity ^@ Belongs to the sigma-54 factor family. http://togogenome.org/gene/1045858:BINT_RS02190 ^@ http://purl.uniprot.org/uniprot/G0EJ00 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M24A family.|||Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions.|||Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed. http://togogenome.org/gene/1045858:BINT_RS07940 ^@ http://purl.uniprot.org/uniprot/G0EI68 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS11925 ^@ http://purl.uniprot.org/uniprot/G0EMY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS02280 ^@ http://purl.uniprot.org/uniprot/G0EJ16 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliN/MopA/SpaO family.|||Cell membrane|||FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1045858:BINT_RS02075 ^@ http://purl.uniprot.org/uniprot/G0EIX7 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the endoribonuclease YbeY family.|||Binds 1 zinc ion.|||Cytoplasm|||Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. http://togogenome.org/gene/1045858:BINT_RS13640 ^@ http://purl.uniprot.org/uniprot/G0EQR9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RNA methyltransferase TrmD family.|||Cytoplasm|||Homodimer.|||Specifically methylates guanosine-37 in various tRNAs. http://togogenome.org/gene/1045858:BINT_RS11550 ^@ http://purl.uniprot.org/uniprot/G0EMI1 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the histidinol dehydrogenase family.|||Binds 1 zinc ion per subunit.|||Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine. http://togogenome.org/gene/1045858:BINT_RS04775 ^@ http://purl.uniprot.org/uniprot/G0ELT5 ^@ Activity Regulation|||Caution|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.|||Belongs to the CTP synthase family.|||CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.|||Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS02895 ^@ http://purl.uniprot.org/uniprot/G0EJU4 ^@ Caution ^@ Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS11015 ^@ http://purl.uniprot.org/uniprot/G0ELZ4 ^@ Similarity ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. http://togogenome.org/gene/1045858:BINT_RS13590 ^@ http://purl.uniprot.org/uniprot/G0EQR0 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M20B family.|||Binds 2 Zn(2+) ions per subunit. http://togogenome.org/gene/1045858:BINT_RS03550 ^@ http://purl.uniprot.org/uniprot/G0EKF7 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS06835 ^@ http://purl.uniprot.org/uniprot/G0EPT8 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein ModA family. http://togogenome.org/gene/1045858:BINT_RS13210 ^@ http://purl.uniprot.org/uniprot/G0EQ22 ^@ Cofactor|||Function|||Similarity ^@ Binds 1 zinc ion per subunit.|||Binds 2 divalent metal cations per subunit. Magnesium or manganese.|||Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.|||Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.|||In the C-terminal section; belongs to the GTP cyclohydrolase II family.|||In the N-terminal section; belongs to the DHBP synthase family. http://togogenome.org/gene/1045858:BINT_RS10480 ^@ http://purl.uniprot.org/uniprot/G0ELG2 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1045858:BINT_RS06620 ^@ http://purl.uniprot.org/uniprot/G0EP83 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the type III secretion exporter family.|||Cell membrane|||Membrane|||Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin. http://togogenome.org/gene/1045858:BINT_RS13465 ^@ http://purl.uniprot.org/uniprot/G0EQ72 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the transaldolase family. Type 3B subfamily.|||Cytoplasm|||Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. http://togogenome.org/gene/1045858:BINT_RS10425 ^@ http://purl.uniprot.org/uniprot/G0ELF1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS07515 ^@ http://purl.uniprot.org/uniprot/G0EQP3 ^@ Similarity ^@ Belongs to the peptidase S14 family. http://togogenome.org/gene/1045858:BINT_RS10120 ^@ http://purl.uniprot.org/uniprot/G0EL08 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1045858:BINT_RS08110 ^@ http://purl.uniprot.org/uniprot/G0EIQ9 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1045858:BINT_RS08330 ^@ http://purl.uniprot.org/uniprot/G0EIV5 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. http://togogenome.org/gene/1045858:BINT_RS05510 ^@ http://purl.uniprot.org/uniprot/G0EMP0 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1045858:BINT_RS11605 ^@ http://purl.uniprot.org/uniprot/G0EMS1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL33 family. http://togogenome.org/gene/1045858:BINT_RS06430 ^@ http://purl.uniprot.org/uniprot/G0EP46 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09785 ^@ http://purl.uniprot.org/uniprot/G0EKK9 ^@ Function|||Subcellular Location Annotation ^@ Component of the core of the flagella.|||Periplasmic flagellum http://togogenome.org/gene/1045858:BINT_RS05460 ^@ http://purl.uniprot.org/uniprot/G0EMN0 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the guanylate kinase family.|||Cytoplasm|||Essential for recycling GMP and indirectly, cGMP. http://togogenome.org/gene/1045858:BINT_RS00210 ^@ http://purl.uniprot.org/uniprot/G0EP05 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1045858:BINT_RS09085 ^@ http://purl.uniprot.org/uniprot/G0EJQ8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.|||Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.|||Cytoplasm|||Homodimer, may be a subunit of the RNA degradosome. http://togogenome.org/gene/1045858:BINT_RS02185 ^@ http://purl.uniprot.org/uniprot/G0EIZ9 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the chorismate synthase family.|||Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Reduced FMN (FMNH(2)). http://togogenome.org/gene/1045858:BINT_RS11250 ^@ http://purl.uniprot.org/uniprot/G0EMB8 ^@ Similarity ^@ Belongs to the formate--tetrahydrofolate ligase family. http://togogenome.org/gene/1045858:BINT_RS03760 ^@ http://purl.uniprot.org/uniprot/G0EKS8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS12070 ^@ http://purl.uniprot.org/uniprot/G0EN98 ^@ Function|||Similarity ^@ Belongs to the acetyl-CoA hydrolase/transferase family. Butyryl-CoA CoA-transferase subfamily.|||Coenzyme A-transferase that converts butyryl-CoA to butyrate. http://togogenome.org/gene/1045858:BINT_RS00855 ^@ http://purl.uniprot.org/uniprot/G0EQA5 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the aspartate-semialdehyde dehydrogenase family.|||Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS02300 ^@ http://purl.uniprot.org/uniprot/G0EJ20 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DapB family.|||Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction. http://togogenome.org/gene/1045858:BINT_RS01235 ^@ http://purl.uniprot.org/uniprot/G0EHS5 ^@ Similarity ^@ Belongs to the DNA repair enzymes AP/ExoA family. http://togogenome.org/gene/1045858:BINT_RS02310 ^@ http://purl.uniprot.org/uniprot/G0EJ22 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1045858:BINT_RS12380 ^@ http://purl.uniprot.org/uniprot/G0ENN9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the thioester dehydratase family. FabZ subfamily.|||Cytoplasm|||Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. http://togogenome.org/gene/1045858:BINT_RS03185 ^@ http://purl.uniprot.org/uniprot/G0EK03 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1045858:BINT_RS08750 ^@ http://purl.uniprot.org/uniprot/G0EJB3 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.|||Belongs to the type II topoisomerase GyrB family.|||Belongs to the type II topoisomerase family.|||Cytoplasm|||Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.|||Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis. http://togogenome.org/gene/1045858:BINT_RS08745 ^@ http://purl.uniprot.org/uniprot/G0EJB2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.|||Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS11495 ^@ http://purl.uniprot.org/uniprot/G0EMG8 ^@ Similarity ^@ Belongs to the glutathione peroxidase family. http://togogenome.org/gene/1045858:BINT_RS02785 ^@ http://purl.uniprot.org/uniprot/G0EJJ1 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the BBS4 family.|||Membrane|||centrosome|||cilium membrane http://togogenome.org/gene/1045858:BINT_RS03395 ^@ http://purl.uniprot.org/uniprot/G0EKC6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Acts as a magnesium transporter.|||Belongs to the SLC41A transporter family.|||Cell membrane|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane http://togogenome.org/gene/1045858:BINT_RS04800 ^@ http://purl.uniprot.org/uniprot/G0ELU0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS05705 ^@ http://purl.uniprot.org/uniprot/G0EN07 ^@ Similarity ^@ Belongs to the anti-sigma-factor antagonist family. http://togogenome.org/gene/1045858:BINT_RS11890 ^@ http://purl.uniprot.org/uniprot/G0EMX7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the HisA/HisF family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS00115 ^@ http://purl.uniprot.org/uniprot/G0ENY6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.|||Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS05665 ^@ http://purl.uniprot.org/uniprot/G0EMZ9 ^@ Similarity ^@ Belongs to the LysR transcriptional regulatory family. http://togogenome.org/gene/1045858:BINT_RS09975 ^@ http://purl.uniprot.org/uniprot/G0EKX8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the AzlC family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12775 ^@ http://purl.uniprot.org/uniprot/G0EPC7 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1045858:BINT_RS12485 ^@ http://purl.uniprot.org/uniprot/G0ENQ9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS14 family. Zinc-binding uS14 subfamily.|||Binds 1 zinc ion per subunit.|||Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.|||Part of the 30S ribosomal subunit. Contacts proteins S3 and S10. http://togogenome.org/gene/1045858:BINT_RS09895 ^@ http://purl.uniprot.org/uniprot/G0EKN2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS03415 ^@ http://purl.uniprot.org/uniprot/G0EKD0 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1045858:BINT_RS02140 ^@ http://purl.uniprot.org/uniprot/G0EIZ0 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1045858:BINT_RS13220 ^@ http://purl.uniprot.org/uniprot/G0EQ23 ^@ Function|||Similarity ^@ Belongs to the DMRL synthase family.|||Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. http://togogenome.org/gene/1045858:BINT_RS00820 ^@ http://purl.uniprot.org/uniprot/G0EQ98 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RuvB family.|||Forms a complex with RuvA.|||The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. http://togogenome.org/gene/1045858:BINT_RS06210 ^@ http://purl.uniprot.org/uniprot/G0ENJ2 ^@ Similarity ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1045858:BINT_RS08430 ^@ http://purl.uniprot.org/uniprot/G0EJ53 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the flotillin-like FloA family.|||Cell membrane|||Found in functional membrane microdomains (FMM) that may be equivalent to eukaryotic membrane rafts FMMs are highly dynamic and increase in number as cells age. Flotillins are thought to be important factors in membrane fluidity.|||Homooligomerizes.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane raft http://togogenome.org/gene/1045858:BINT_RS13275 ^@ http://purl.uniprot.org/uniprot/G0EQ34 ^@ Similarity ^@ Belongs to the SIS family. GutQ/KpsF subfamily. http://togogenome.org/gene/1045858:BINT_RS10765 ^@ http://purl.uniprot.org/uniprot/G0ELL5 ^@ Function|||Similarity ^@ Belongs to the AIR carboxylase family. Class I subfamily.|||Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). http://togogenome.org/gene/1045858:BINT_RS08095 ^@ http://purl.uniprot.org/uniprot/G0EIQ6 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1045858:BINT_RS05425 ^@ http://purl.uniprot.org/uniprot/G0EMM3 ^@ Cofactor|||Domain|||Function|||Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.|||Binds 1 NADP(+) per subunit.|||Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.|||Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.|||Homopentamer. http://togogenome.org/gene/1045858:BINT_RS11120 ^@ http://purl.uniprot.org/uniprot/G0EM14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RecF family.|||Cytoplasm|||The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. http://togogenome.org/gene/1045858:BINT_RS13705 ^@ http://purl.uniprot.org/uniprot/G0EQT2 ^@ Similarity ^@ Belongs to the V-ATPase D subunit family. http://togogenome.org/gene/1045858:BINT_RS06985 ^@ http://purl.uniprot.org/uniprot/G0EPX0 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1045858:BINT_RS12870 ^@ http://purl.uniprot.org/uniprot/G0EPE1 ^@ Cofactor|||Similarity|||Subunit ^@ Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.|||Binds 1 FAD per subunit.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS07375 ^@ http://purl.uniprot.org/uniprot/G0EQL0 ^@ Function|||Similarity ^@ Belongs to the CheD family.|||Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis. http://togogenome.org/gene/1045858:BINT_RS09340 ^@ http://purl.uniprot.org/uniprot/G0EK40 ^@ Similarity ^@ Belongs to the enoyl-CoA hydratase/isomerase family. http://togogenome.org/gene/1045858:BINT_RS04245 ^@ http://purl.uniprot.org/uniprot/G0ELA3 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. NagA family. http://togogenome.org/gene/1045858:BINT_RS05940 ^@ http://purl.uniprot.org/uniprot/G0EN56 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the DnaJ family.|||Binds 2 Zn(2+) ions per monomer.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.|||The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity. http://togogenome.org/gene/1045858:BINT_RS11795 ^@ http://purl.uniprot.org/uniprot/G0EMV9 ^@ Similarity ^@ Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. http://togogenome.org/gene/1045858:BINT_RS12580 ^@ http://purl.uniprot.org/uniprot/G0ENS8 ^@ Similarity|||Subcellular Location Annotation ^@ Cytoplasm|||In the C-terminal section; belongs to the PRA-PH family.|||In the N-terminal section; belongs to the PRA-CH family. http://togogenome.org/gene/1045858:BINT_RS03015 ^@ http://purl.uniprot.org/uniprot/G0EJW8 ^@ Subcellular Location Annotation ^@ Periplasmic flagellum http://togogenome.org/gene/1045858:BINT_RS12480 ^@ http://purl.uniprot.org/uniprot/G0ENQ8 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS8 family.|||One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.|||Part of the 30S ribosomal subunit. Contacts proteins S5 and S12. http://togogenome.org/gene/1045858:BINT_RS00705 ^@ http://purl.uniprot.org/uniprot/G0EPR7 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS03120 ^@ http://purl.uniprot.org/uniprot/G0EJZ1 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL28 family. http://togogenome.org/gene/1045858:BINT_RS10250 ^@ http://purl.uniprot.org/uniprot/G0EL37 ^@ Function|||Similarity|||Subunit ^@ Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.|||Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).|||Homotetramer. http://togogenome.org/gene/1045858:BINT_RS06505 ^@ http://purl.uniprot.org/uniprot/G0EP61 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS09205 ^@ http://purl.uniprot.org/uniprot/G0EK13 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1045858:BINT_RS11455 ^@ http://purl.uniprot.org/uniprot/G0EMG0 ^@ Similarity ^@ Belongs to the Glu/Leu/Phe/Val dehydrogenases family. http://togogenome.org/gene/1045858:BINT_RS04535 ^@ http://purl.uniprot.org/uniprot/G0ELN6 ^@ Similarity|||Subunit ^@ Belongs to the methylthioribose kinase family.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS05115 ^@ http://purl.uniprot.org/uniprot/G0EM80 ^@ Function|||Similarity ^@ Belongs to the NifU family.|||May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins. http://togogenome.org/gene/1045858:BINT_RS04690 ^@ http://purl.uniprot.org/uniprot/G0ELR7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the diaminopimelate epimerase family.|||Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS11545 ^@ http://purl.uniprot.org/uniprot/G0EMI0 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATP phosphoribosyltransferase family. Short subfamily.|||Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.|||Cytoplasm|||Heteromultimer composed of HisG and HisZ subunits.|||Lacks the C-terminal regulatory region which is replaced by HisZ. http://togogenome.org/gene/1045858:BINT_RS01880 ^@ http://purl.uniprot.org/uniprot/G0EIK9 ^@ Similarity ^@ Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS00915 ^@ http://purl.uniprot.org/uniprot/G0EQB8 ^@ Function|||Similarity ^@ Belongs to the thymidylate kinase family.|||Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis. http://togogenome.org/gene/1045858:BINT_RS03875 ^@ http://purl.uniprot.org/uniprot/G0EKV3 ^@ Function|||Similarity ^@ Belongs to the flavodoxin family.|||Low-potential electron donor to a number of redox enzymes. http://togogenome.org/gene/1045858:BINT_RS11110 ^@ http://purl.uniprot.org/uniprot/G0EM12 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AdoMet synthase family.|||Binds 1 potassium ion per subunit.|||Binds 2 divalent ions per subunit.|||Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.|||Cytoplasm|||Homotetramer; dimer of dimers.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS06565 ^@ http://purl.uniprot.org/uniprot/G0EP72 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TsaE family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS05120 ^@ http://purl.uniprot.org/uniprot/G0EM81 ^@ Function|||Similarity|||Subunit ^@ Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.|||Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS03390 ^@ http://purl.uniprot.org/uniprot/G0EKC5 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.|||Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.|||Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS14080 ^@ http://purl.uniprot.org/uniprot/G0EI94 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS05260 ^@ http://purl.uniprot.org/uniprot/G0EMJ0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12720 ^@ http://purl.uniprot.org/uniprot/G0ENV5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1045858:BINT_RS06120 ^@ http://purl.uniprot.org/uniprot/G0ENH2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS12520 ^@ http://purl.uniprot.org/uniprot/G0ENR6 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS3 family.|||Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.|||Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14. http://togogenome.org/gene/1045858:BINT_RS04160 ^@ http://purl.uniprot.org/uniprot/G0EL87 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MnmA/TRMU family.|||Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS02370 ^@ http://purl.uniprot.org/uniprot/G0EJ33 ^@ Similarity ^@ Belongs to the Skp family. http://togogenome.org/gene/1045858:BINT_RS06875 ^@ http://purl.uniprot.org/uniprot/G0EPU6 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS11090 ^@ http://purl.uniprot.org/uniprot/G0EM08 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01910 ^@ http://purl.uniprot.org/uniprot/G0EIL5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS00805 ^@ http://purl.uniprot.org/uniprot/G0EQ95 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the RecX family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS10540 ^@ http://purl.uniprot.org/uniprot/G0ELH1 ^@ Similarity ^@ Belongs to the LytR/CpsA/Psr (LCP) family. http://togogenome.org/gene/1045858:BINT_RS12500 ^@ http://purl.uniprot.org/uniprot/G0ENR2 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL14 family.|||Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.|||Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8. http://togogenome.org/gene/1045858:BINT_RS12390 ^@ http://purl.uniprot.org/uniprot/G0ENP1 ^@ Function ^@ Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. http://togogenome.org/gene/1045858:BINT_RS05815 ^@ http://purl.uniprot.org/uniprot/G0EN29 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS07235 ^@ http://purl.uniprot.org/uniprot/G0EQI2 ^@ Similarity ^@ Belongs to the methylenetetrahydrofolate reductase family. http://togogenome.org/gene/1045858:BINT_RS10175 ^@ http://purl.uniprot.org/uniprot/G0EL21 ^@ Function|||Similarity ^@ Belongs to the bacterial ribosomal protein bS6 family.|||Binds together with S18 to 16S ribosomal RNA. http://togogenome.org/gene/1045858:BINT_RS03990 ^@ http://purl.uniprot.org/uniprot/G0EKX4 ^@ Function|||Subunit ^@ Catalyzes the synthesis of GMP from XMP.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS09675 ^@ http://purl.uniprot.org/uniprot/G0EKI7 ^@ Function|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.|||Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. http://togogenome.org/gene/1045858:BINT_RS08450 ^@ http://purl.uniprot.org/uniprot/G0EJ57 ^@ Similarity ^@ Belongs to the peptidase M29 family. http://togogenome.org/gene/1045858:BINT_RS04515 ^@ http://purl.uniprot.org/uniprot/G0ELN2 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylate kinase family.|||Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.|||Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS04310 ^@ http://purl.uniprot.org/uniprot/G0ELB5 ^@ Function|||PTM|||Similarity|||Subcellular Location Annotation ^@ 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.|||4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.|||Belongs to the acyl carrier protein (ACP) family.|||Carrier of the growing fatty acid chain in fatty acid biosynthesis.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS03795 ^@ http://purl.uniprot.org/uniprot/G0EKT6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the GmhB family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS03225 ^@ http://purl.uniprot.org/uniprot/G0EK92 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL27 family. http://togogenome.org/gene/1045858:BINT_RS00145 ^@ http://purl.uniprot.org/uniprot/G0ENZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS08675 ^@ http://purl.uniprot.org/uniprot/G0EJ98 ^@ Function|||Similarity ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.|||Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. http://togogenome.org/gene/1045858:BINT_RS07155 ^@ http://purl.uniprot.org/uniprot/G0EQ06 ^@ Similarity ^@ Belongs to the TPP enzyme family. http://togogenome.org/gene/1045858:BINT_RS08010 ^@ http://purl.uniprot.org/uniprot/G0EIN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12465 ^@ http://purl.uniprot.org/uniprot/G0ENQ5 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS5 family.|||Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.|||Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.|||The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.|||With S4 and S12 plays an important role in translational accuracy. http://togogenome.org/gene/1045858:BINT_RS11565 ^@ http://purl.uniprot.org/uniprot/G0EMR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1045858:BINT_RS08615 ^@ http://purl.uniprot.org/uniprot/G0EJ86 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the glycosyltransferase group 1 family.|||Cell membrane|||Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A. http://togogenome.org/gene/1045858:BINT_RS05380 ^@ http://purl.uniprot.org/uniprot/G0EML4 ^@ Cofactor|||Similarity ^@ Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.|||Binds 1 zinc ion per subunit. http://togogenome.org/gene/1045858:BINT_RS13025 ^@ http://purl.uniprot.org/uniprot/G0EPH3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GroES chaperonin family.|||Cytoplasm|||Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.|||Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. http://togogenome.org/gene/1045858:BINT_RS09505 ^@ http://purl.uniprot.org/uniprot/G0EK73 ^@ Function|||Similarity ^@ Belongs to the GreA/GreB family.|||Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. http://togogenome.org/gene/1045858:BINT_RS13790 ^@ http://purl.uniprot.org/uniprot/G0EQU9 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.|||Cell inner membrane|||Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner. http://togogenome.org/gene/1045858:BINT_RS04650 ^@ http://purl.uniprot.org/uniprot/G0ELQ8 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurB family.|||Cell wall formation.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS08820 ^@ http://purl.uniprot.org/uniprot/G0EJK6 ^@ Similarity ^@ Belongs to the SAM hydrolase / SAM-dependent halogenase family. http://togogenome.org/gene/1045858:BINT_RS03610 ^@ http://purl.uniprot.org/uniprot/G0EKP8 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1045858:BINT_RS14295 ^@ http://purl.uniprot.org/uniprot/G0EID7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS09170 ^@ http://purl.uniprot.org/uniprot/G0EJS6 ^@ Function|||Similarity ^@ Belongs to the 2H phosphoesterase superfamily. ThpR family.|||Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester. http://togogenome.org/gene/1045858:BINT_RS11570 ^@ http://purl.uniprot.org/uniprot/G0EMR5 ^@ Function|||Similarity|||Subunit ^@ Belongs to the bacterial ribosomal protein bL12 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.|||Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors. http://togogenome.org/gene/1045858:BINT_RS00105 ^@ http://purl.uniprot.org/uniprot/G0ENY4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS12295 ^@ http://purl.uniprot.org/uniprot/G0ENE2 ^@ Similarity ^@ Belongs to the universal ribosomal protein uS9 family. http://togogenome.org/gene/1045858:BINT_RS14120 ^@ http://purl.uniprot.org/uniprot/G0EIA2 ^@ Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. http://togogenome.org/gene/1045858:BINT_RS10265 ^@ http://purl.uniprot.org/uniprot/G0EL40 ^@ Cofactor|||Similarity ^@ Belongs to the TPP enzyme family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit. http://togogenome.org/gene/1045858:BINT_RS09515 ^@ http://purl.uniprot.org/uniprot/G0EK75 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS07695 ^@ http://purl.uniprot.org/uniprot/G0EI21 ^@ Similarity ^@ Belongs to the threonine aldolase family. http://togogenome.org/gene/1045858:BINT_RS01800 ^@ http://purl.uniprot.org/uniprot/G0EIJ3 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1045858:BINT_RS13015 ^@ http://purl.uniprot.org/uniprot/G0EPH1 ^@ Similarity ^@ Belongs to the FGGY kinase family. http://togogenome.org/gene/1045858:BINT_RS10180 ^@ http://purl.uniprot.org/uniprot/G0EL22 ^@ Caution|||Subunit ^@ Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS08255 ^@ http://purl.uniprot.org/uniprot/G0EIU0 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation ^@ Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.|||Belongs to the UppP family.|||Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.|||Cell inner membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS09945 ^@ http://purl.uniprot.org/uniprot/G0EKP2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the sigma-70 factor family. RpoD/SigA subfamily.|||Cytoplasm|||Interacts transiently with the RNA polymerase catalytic core.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. http://togogenome.org/gene/1045858:BINT_RS03730 ^@ http://purl.uniprot.org/uniprot/G0EKS2 ^@ Similarity ^@ Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS09700 ^@ http://purl.uniprot.org/uniprot/G0EKJ2 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1045858:BINT_RS01120 ^@ http://purl.uniprot.org/uniprot/G0EQG0 ^@ Similarity ^@ Belongs to the shaker potassium channel beta subunit family. http://togogenome.org/gene/1045858:BINT_RS07990 ^@ http://purl.uniprot.org/uniprot/G0EIN5 ^@ Subcellular Location Annotation ^@ Bacterial microcompartment http://togogenome.org/gene/1045858:BINT_RS01425 ^@ http://purl.uniprot.org/uniprot/G0EHW3 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS01090 ^@ http://purl.uniprot.org/uniprot/G0EQF4 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS00175 ^@ http://purl.uniprot.org/uniprot/G0ENZ8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS06685 ^@ http://purl.uniprot.org/uniprot/G0EP98 ^@ Similarity ^@ Belongs to the homoserine dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS02915 ^@ http://purl.uniprot.org/uniprot/G0EJU8 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Cytoplasm|||Tetramer of two alpha and two beta subunits. http://togogenome.org/gene/1045858:BINT_RS14200 ^@ http://purl.uniprot.org/uniprot/G0EIB7 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the RnfG family.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1045858:BINT_RS09255 ^@ http://purl.uniprot.org/uniprot/G0EK23 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS08535 ^@ http://purl.uniprot.org/uniprot/G0EJ73 ^@ Function|||Similarity ^@ Belongs to the dihydrofolate reductase family.|||Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. http://togogenome.org/gene/1045858:BINT_RS02750 ^@ http://purl.uniprot.org/uniprot/G0EJI3 ^@ Similarity ^@ Belongs to the FPP/GGPP synthase family. http://togogenome.org/gene/1045858:BINT_RS13515 ^@ http://purl.uniprot.org/uniprot/G0EQ82 ^@ Similarity ^@ Belongs to the arginase family. http://togogenome.org/gene/1045858:BINT_RS02515 ^@ http://purl.uniprot.org/uniprot/G0EJE2 ^@ Similarity ^@ Belongs to the peptidase S58 family. http://togogenome.org/gene/1045858:BINT_RS08435 ^@ http://purl.uniprot.org/uniprot/G0EJ54 ^@ Activity Regulation|||Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the UMP kinase family.|||Catalyzes the reversible phosphorylation of UMP to UDP.|||Cytoplasm|||Homohexamer.|||Inhibited by UTP.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS13915 ^@ http://purl.uniprot.org/uniprot/G0EQX4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10825 ^@ http://purl.uniprot.org/uniprot/G0ELV5 ^@ Similarity ^@ Belongs to the helicase family. UvrD subfamily. http://togogenome.org/gene/1045858:BINT_RS12475 ^@ http://purl.uniprot.org/uniprot/G0ENQ7 ^@ Function|||Similarity ^@ Belongs to the universal ribosomal protein uL6 family.|||This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center. http://togogenome.org/gene/1045858:BINT_RS08635 ^@ http://purl.uniprot.org/uniprot/G0EJ90 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.|||Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.|||Cytoplasm|||Monomer.|||The C-terminal coiled-coil domain is crucial for aminoacylation activity.|||ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site. http://togogenome.org/gene/1045858:BINT_RS13865 ^@ http://purl.uniprot.org/uniprot/G0EQW4 ^@ Activity Regulation|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the enolase family.|||Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.|||Cell surface|||Cytoplasm|||Secreted|||The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein. http://togogenome.org/gene/1045858:BINT_RS10280 ^@ http://purl.uniprot.org/uniprot/G0EL43 ^@ Function|||Similarity ^@ Belongs to the cyclophilin-type PPIase family.|||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. http://togogenome.org/gene/1045858:BINT_RS13860 ^@ http://purl.uniprot.org/uniprot/G0EQW3 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1045858:BINT_RS09235 ^@ http://purl.uniprot.org/uniprot/G0EK19 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1045858:BINT_RS08790 ^@ http://purl.uniprot.org/uniprot/G0EJK0 ^@ Cofactor|||Function|||Similarity ^@ Belongs to the peptidase M3B family.|||Binds 1 zinc ion.|||Has oligopeptidase activity and degrades a variety of small bioactive peptides. http://togogenome.org/gene/1045858:BINT_RS14075 ^@ http://purl.uniprot.org/uniprot/G0EI93 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12885 ^@ http://purl.uniprot.org/uniprot/G0EPE4 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ApbE family.|||Cell inner membrane|||Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.|||Magnesium. Can also use manganese. http://togogenome.org/gene/1045858:BINT_RS00230 ^@ http://purl.uniprot.org/uniprot/G0EP09 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS09665 ^@ http://purl.uniprot.org/uniprot/G0EKI5 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the transketolase family. DXPS subfamily.|||Binds 1 Mg(2+) ion per subunit.|||Binds 1 thiamine pyrophosphate per subunit.|||Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS05750 ^@ http://purl.uniprot.org/uniprot/G0EN16 ^@ Function|||Similarity ^@ Belongs to the helicase family. DnaB subfamily.|||Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. http://togogenome.org/gene/1045858:BINT_RS06960 ^@ http://purl.uniprot.org/uniprot/G0EPW5 ^@ PTM|||Similarity ^@ Belongs to the sulfatase family.|||The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity. http://togogenome.org/gene/1045858:BINT_RS04600 ^@ http://purl.uniprot.org/uniprot/G0ELP8 ^@ Similarity ^@ Belongs to the DtxR/MntR family. http://togogenome.org/gene/1045858:BINT_RS08250 ^@ http://purl.uniprot.org/uniprot/G0EIT9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the FtsK/SpoIIIE/SftA family.|||Homohexamer. Forms a ring that surrounds DNA.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09525 ^@ http://purl.uniprot.org/uniprot/G0EK77 ^@ PTM|||Similarity ^@ Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.|||Carbamylation allows a single lysine to coordinate two divalent metal cations. http://togogenome.org/gene/1045858:BINT_RS08115 ^@ http://purl.uniprot.org/uniprot/G0EIR0 ^@ Similarity ^@ Belongs to the aldose epimerase family. http://togogenome.org/gene/1045858:BINT_RS09400 ^@ http://purl.uniprot.org/uniprot/G0EK52 ^@ Domain|||Function|||Miscellaneous|||Similarity|||Subunit ^@ Belongs to the HPrK/P family.|||Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.|||Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).|||Homohexamer.|||The Walker A ATP-binding motif also binds Pi and PPi. http://togogenome.org/gene/1045858:BINT_RS07950 ^@ http://purl.uniprot.org/uniprot/G0EI70 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS04085 ^@ http://purl.uniprot.org/uniprot/G0EL72 ^@ Function|||Similarity ^@ Belongs to the QueH family.|||Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). http://togogenome.org/gene/1045858:BINT_RS09155 ^@ http://purl.uniprot.org/uniprot/G0EJS2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12635 ^@ http://purl.uniprot.org/uniprot/G0ENT9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS07935 ^@ http://purl.uniprot.org/uniprot/G0EI67 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS01515 ^@ http://purl.uniprot.org/uniprot/G0EHY0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.|||Cell inner membrane|||Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.|||Membrane|||Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. http://togogenome.org/gene/1045858:BINT_RS10945 ^@ http://purl.uniprot.org/uniprot/G0ELY1 ^@ Function|||Similarity ^@ Belongs to the PEP-utilizing enzyme family.|||Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone. http://togogenome.org/gene/1045858:BINT_RS01115 ^@ http://purl.uniprot.org/uniprot/G0EQF9 ^@ Cofactor|||Similarity ^@ Belongs to the malic enzymes family.|||Divalent metal cations. Prefers magnesium or manganese. http://togogenome.org/gene/1045858:BINT_RS01990 ^@ http://purl.uniprot.org/uniprot/G0EIN1 ^@ Caution|||Function|||Similarity ^@ Belongs to the GART family.|||Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS03090 ^@ http://purl.uniprot.org/uniprot/G0EJY5 ^@ Similarity ^@ Belongs to the ClpA/ClpB family. http://togogenome.org/gene/1045858:BINT_RS12420 ^@ http://purl.uniprot.org/uniprot/G0ENP7 ^@ Domain|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase alpha chain family.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.|||The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements. http://togogenome.org/gene/1045858:BINT_RS11930 ^@ http://purl.uniprot.org/uniprot/G0EMY8 ^@ Similarity ^@ Belongs to the zinc-containing alcohol dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS02490 ^@ http://purl.uniprot.org/uniprot/G0EJD7 ^@ Similarity ^@ Belongs to the SorC transcriptional regulatory family. http://togogenome.org/gene/1045858:BINT_RS05525 ^@ http://purl.uniprot.org/uniprot/G0EMP2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.|||Belongs to the RNR ribonuclease family. RNase R subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS09980 ^@ http://purl.uniprot.org/uniprot/G0EKX9 ^@ Caution|||Similarity|||Subcellular Location Annotation ^@ Belongs to the CutC family.|||Cytoplasm|||Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case. http://togogenome.org/gene/1045858:BINT_RS09200 ^@ http://purl.uniprot.org/uniprot/G0EK12 ^@ Caution|||Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the IlvD/Edd family.|||Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.|||Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS01480 ^@ http://purl.uniprot.org/uniprot/G0EHX4 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1045858:BINT_RS07685 ^@ http://purl.uniprot.org/uniprot/G0EI19 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the KAE1 / TsaD family.|||Binds 1 Fe(2+) ion per subunit.|||Cytoplasm|||Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction. http://togogenome.org/gene/1045858:BINT_RS04125 ^@ http://purl.uniprot.org/uniprot/G0EL80 ^@ Cofactor|||Similarity ^@ Belongs to the PyrK family.|||Binds 1 FAD per subunit.|||Binds 1 [2Fe-2S] cluster per subunit. http://togogenome.org/gene/1045858:BINT_RS12510 ^@ http://purl.uniprot.org/uniprot/G0ENR4 ^@ Similarity ^@ Belongs to the universal ribosomal protein uL29 family. http://togogenome.org/gene/1045858:BINT_RS02800 ^@ http://purl.uniprot.org/uniprot/G0EJJ4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS02265 ^@ http://purl.uniprot.org/uniprot/G0EJ13 ^@ Function|||Similarity ^@ Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.|||Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.|||Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. http://togogenome.org/gene/1045858:BINT_RS08000 ^@ http://purl.uniprot.org/uniprot/G0EIN7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01100 ^@ http://purl.uniprot.org/uniprot/G0EQF6 ^@ Caution|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.|||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).|||Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.|||Cytoplasm|||Homodimer. The tRNA molecule binds across the dimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS08660 ^@ http://purl.uniprot.org/uniprot/G0EJ95 ^@ Similarity ^@ Belongs to the transglycosylase Slt family. http://togogenome.org/gene/1045858:BINT_RS07790 ^@ http://purl.uniprot.org/uniprot/G0EI40 ^@ Similarity ^@ Belongs to the ribonucleoside diphosphate reductase small chain family. http://togogenome.org/gene/1045858:BINT_RS13185 ^@ http://purl.uniprot.org/uniprot/G0EQ17 ^@ Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS05500 ^@ http://purl.uniprot.org/uniprot/G0EMN8 ^@ Subcellular Location Annotation ^@ Cytoplasm http://togogenome.org/gene/1045858:BINT_RS05505 ^@ http://purl.uniprot.org/uniprot/G0EMN9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the FliJ family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS01630 ^@ http://purl.uniprot.org/uniprot/G0EIF9 ^@ Function ^@ Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif. http://togogenome.org/gene/1045858:BINT_RS09450 ^@ http://purl.uniprot.org/uniprot/G0EK62 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the KdsA family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS14105 ^@ http://purl.uniprot.org/uniprot/G0EI99 ^@ Similarity ^@ Belongs to the aspartokinase family. http://togogenome.org/gene/1045858:BINT_RS10140 ^@ http://purl.uniprot.org/uniprot/G0EL12 ^@ Similarity ^@ Belongs to the FldB/FldC dehydratase alpha/beta subunit family. http://togogenome.org/gene/1045858:BINT_RS04895 ^@ http://purl.uniprot.org/uniprot/G0EM38 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the SecA family.|||Cell inner membrane|||Cytoplasm|||Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.|||Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. http://togogenome.org/gene/1045858:BINT_RS09475 ^@ http://purl.uniprot.org/uniprot/G0EK67 ^@ Similarity ^@ Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. http://togogenome.org/gene/1045858:BINT_RS09190 ^@ http://purl.uniprot.org/uniprot/G0EK10 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1045858:BINT_RS02510 ^@ http://purl.uniprot.org/uniprot/G0EJE1 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1045858:BINT_RS04060 ^@ http://purl.uniprot.org/uniprot/G0EL68 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS02180 ^@ http://purl.uniprot.org/uniprot/G0EIZ8 ^@ Similarity ^@ Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. http://togogenome.org/gene/1045858:BINT_RS05090 ^@ http://purl.uniprot.org/uniprot/G0EM75 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the cytidylate kinase family. Type 1 subfamily.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS02005 ^@ http://purl.uniprot.org/uniprot/G0EIW5 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CpxP/Spy family.|||Periplasm http://togogenome.org/gene/1045858:BINT_RS10155 ^@ http://purl.uniprot.org/uniprot/G0EL16 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the UPF0394 family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09345 ^@ http://purl.uniprot.org/uniprot/G0EK41 ^@ Similarity ^@ Belongs to the thiolase-like superfamily. Thiolase family. http://togogenome.org/gene/1045858:BINT_RS09270 ^@ http://purl.uniprot.org/uniprot/G0EK26 ^@ Similarity ^@ Belongs to the radical SAM superfamily. Anaerobic sulfatase-maturating enzyme family. http://togogenome.org/gene/1045858:BINT_RS09320 ^@ http://purl.uniprot.org/uniprot/G0EK36 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family. http://togogenome.org/gene/1045858:BINT_RS08965 ^@ http://purl.uniprot.org/uniprot/G0EJN4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the HsdR family.|||Subunit R is required for both nuclease and ATPase activities, but not for modification.|||The type I restriction/modification system is composed of three polypeptides R, M and S. http://togogenome.org/gene/1045858:BINT_RS10580 ^@ http://purl.uniprot.org/uniprot/G0ELI0 ^@ Cofactor|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-II aminoacyl-tRNA synthetase family.|||Binds 3 Mg(2+) ions per subunit.|||Cytoplasm|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS04475 ^@ http://purl.uniprot.org/uniprot/G0ELM7 ^@ Domain|||Function|||Similarity ^@ Belongs to the RecA family. RadA subfamily.|||DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.|||Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.|||The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease. http://togogenome.org/gene/1045858:BINT_RS08025 ^@ http://purl.uniprot.org/uniprot/G0EIP2 ^@ Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ArgJ family.|||Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.|||Cytoplasm|||Heterotetramer of two alpha and two beta chains.|||Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway. http://togogenome.org/gene/1045858:BINT_RS03360 ^@ http://purl.uniprot.org/uniprot/G0EKB9 ^@ Similarity ^@ Belongs to the RutC family. http://togogenome.org/gene/1045858:BINT_RS11785 ^@ http://purl.uniprot.org/uniprot/G0EMV7 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS13970 ^@ http://purl.uniprot.org/uniprot/G0EI76 ^@ Function|||Similarity ^@ Belongs to the alanine racemase family.|||Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids. http://togogenome.org/gene/1045858:BINT_RS02270 ^@ http://purl.uniprot.org/uniprot/G0EJ14 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the FliL family.|||Cell membrane|||Controls the rotational direction of flagella during chemotaxis.|||Membrane http://togogenome.org/gene/1045858:BINT_RS01325 ^@ http://purl.uniprot.org/uniprot/G0EHU4 ^@ Caution|||Similarity ^@ Belongs to the ATP:guanido phosphotransferase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS05780 ^@ http://purl.uniprot.org/uniprot/G0EN22 ^@ Function|||Similarity|||Subunit ^@ Belongs to the peptidase S24 family.|||Homodimer.|||Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. http://togogenome.org/gene/1045858:BINT_RS12415 ^@ http://purl.uniprot.org/uniprot/G0ENP6 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL17 family. http://togogenome.org/gene/1045858:BINT_RS09730 ^@ http://purl.uniprot.org/uniprot/G0EKJ8 ^@ Similarity ^@ Belongs to the DegT/DnrJ/EryC1 family. http://togogenome.org/gene/1045858:BINT_RS11555 ^@ http://purl.uniprot.org/uniprot/G0EMI2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12430 ^@ http://purl.uniprot.org/uniprot/G0ENP9 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uS11 family.|||Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.|||Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3. http://togogenome.org/gene/1045858:BINT_RS12285 ^@ http://purl.uniprot.org/uniprot/G0ENE0 ^@ Caution|||Function|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the pantothenate synthetase family.|||Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||The reaction proceeds by a bi uni uni bi ping pong mechanism. http://togogenome.org/gene/1045858:BINT_RS09465 ^@ http://purl.uniprot.org/uniprot/G0EK65 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 3 family. http://togogenome.org/gene/1045858:BINT_RS08360 ^@ http://purl.uniprot.org/uniprot/G0EIW2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the RRF family.|||Cytoplasm|||Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another. http://togogenome.org/gene/1045858:BINT_RS01870 ^@ http://purl.uniprot.org/uniprot/G0EIK7 ^@ Similarity ^@ Belongs to the complex I 51 kDa subunit family. http://togogenome.org/gene/1045858:BINT_RS00055 ^@ http://purl.uniprot.org/uniprot/G0ENX3 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family.|||Cytoplasm|||Monomer. http://togogenome.org/gene/1045858:BINT_RS10075 ^@ http://purl.uniprot.org/uniprot/G0EKZ8 ^@ Subcellular Location Annotation ^@ Cell inner membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS05910 ^@ http://purl.uniprot.org/uniprot/G0EN50 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the GrpE family.|||Cytoplasm|||Homodimer.|||Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. http://togogenome.org/gene/1045858:BINT_RS08605 ^@ http://purl.uniprot.org/uniprot/G0EJ84 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS01570 ^@ http://purl.uniprot.org/uniprot/G0EHZ1 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the AB hydrolase superfamily. MetX family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. http://togogenome.org/gene/1045858:BINT_RS12865 ^@ http://purl.uniprot.org/uniprot/G0EPE0 ^@ Similarity ^@ Belongs to the Mg-chelatase subunits D/I family. ComM subfamily. http://togogenome.org/gene/1045858:BINT_RS04525 ^@ http://purl.uniprot.org/uniprot/G0ELN4 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1045858:BINT_RS04280 ^@ http://purl.uniprot.org/uniprot/G0ELA9 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the NnrD/CARKD family.|||Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Binds 1 potassium ion per subunit.|||Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.|||Homotetramer.|||In the C-terminal section; belongs to the NnrD/CARKD family.|||In the N-terminal section; belongs to the NnrE/AIBP family. http://togogenome.org/gene/1045858:BINT_RS07240 ^@ http://purl.uniprot.org/uniprot/G0EQI3 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS08020 ^@ http://purl.uniprot.org/uniprot/G0EIP1 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.|||Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS02770 ^@ http://purl.uniprot.org/uniprot/G0EJI8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS00710 ^@ http://purl.uniprot.org/uniprot/G0EPR8 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS11185 ^@ http://purl.uniprot.org/uniprot/G0EMA5 ^@ Caution|||Cofactor|||Similarity|||Subunit ^@ Belongs to the CarB family.|||Binds 4 Mg(2+) or Mn(2+) ions per subunit.|||Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS01940 ^@ http://purl.uniprot.org/uniprot/G0EIM1 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1045858:BINT_RS12245 ^@ http://purl.uniprot.org/uniprot/G0END2 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase B chain family.|||Cell inner membrane|||Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Membrane http://togogenome.org/gene/1045858:BINT_RS08575 ^@ http://purl.uniprot.org/uniprot/G0EJ80 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the chaperonin (HSP60) family.|||Cytoplasm|||Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. http://togogenome.org/gene/1045858:BINT_RS03190 ^@ http://purl.uniprot.org/uniprot/G0EK04 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the bacterial CoaD family.|||Cytoplasm|||Homohexamer.|||Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. http://togogenome.org/gene/1045858:BINT_RS02150 ^@ http://purl.uniprot.org/uniprot/G0EIZ2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the exbB/tolQ family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09580 ^@ http://purl.uniprot.org/uniprot/G0EKG8 ^@ Similarity ^@ Belongs to the carbamate kinase family. http://togogenome.org/gene/1045858:BINT_RS14225 ^@ http://purl.uniprot.org/uniprot/G0EIC2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL32 family. http://togogenome.org/gene/1045858:BINT_RS09820 ^@ http://purl.uniprot.org/uniprot/G0EKL8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS14930 ^@ http://purl.uniprot.org/uniprot/G0EKX1 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS00720 ^@ http://purl.uniprot.org/uniprot/G0EPS0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS00280 ^@ http://purl.uniprot.org/uniprot/G0EP18 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the adenylosuccinate synthetase family.|||Binds 1 Mg(2+) ion per subunit.|||Cytoplasm|||Homodimer.|||Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. http://togogenome.org/gene/1045858:BINT_RS14320 ^@ http://purl.uniprot.org/uniprot/G0EIE2 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).|||Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS03160 ^@ http://purl.uniprot.org/uniprot/G0EJZ8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS01545 ^@ http://purl.uniprot.org/uniprot/G0EHY6 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the TACO1 family.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS12235 ^@ http://purl.uniprot.org/uniprot/G0END0 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase delta chain family.|||Cell inner membrane|||F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.|||F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction. http://togogenome.org/gene/1045858:BINT_RS03640 ^@ http://purl.uniprot.org/uniprot/G0EKQ4 ^@ Domain|||Similarity ^@ Belongs to the PurH family.|||The IMP cyclohydrolase activity resides in the N-terminal region. http://togogenome.org/gene/1045858:BINT_RS13675 ^@ http://purl.uniprot.org/uniprot/G0EQS6 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1045858:BINT_RS07860 ^@ http://purl.uniprot.org/uniprot/G0EI54 ^@ Subcellular Location Annotation ^@ Membrane|||Nucleus membrane http://togogenome.org/gene/1045858:BINT_RS03175 ^@ http://purl.uniprot.org/uniprot/G0EK01 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase epsilon chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. http://togogenome.org/gene/1045858:BINT_RS03115 ^@ http://purl.uniprot.org/uniprot/G0EJZ0 ^@ Similarity ^@ Belongs to the DapA family. http://togogenome.org/gene/1045858:BINT_RS09015 ^@ http://purl.uniprot.org/uniprot/G0EJP4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the L-fucose isomerase family.|||Converts the aldose L-fucose into the corresponding ketose L-fuculose.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS03890 ^@ http://purl.uniprot.org/uniprot/G0EKV6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the heat shock protein 90 family.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Molecular chaperone. Has ATPase activity. http://togogenome.org/gene/1045858:BINT_RS02520 ^@ http://purl.uniprot.org/uniprot/G0EJE3 ^@ Similarity ^@ Belongs to the short-chain dehydrogenases/reductases (SDR) family. http://togogenome.org/gene/1045858:BINT_RS09365 ^@ http://purl.uniprot.org/uniprot/G0EK45 ^@ Similarity ^@ Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family. http://togogenome.org/gene/1045858:BINT_RS11155 ^@ http://purl.uniprot.org/uniprot/G0EM21 ^@ Similarity ^@ Belongs to the glycosyl hydrolase 2 family. http://togogenome.org/gene/1045858:BINT_RS14150 ^@ http://purl.uniprot.org/uniprot/G0EIA6 ^@ Function|||Similarity|||Subunit ^@ Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).|||Belongs to the GatB/GatE family. GatB subfamily.|||Heterotrimer of A, B and C subunits. http://togogenome.org/gene/1045858:BINT_RS08805 ^@ http://purl.uniprot.org/uniprot/G0EJK3 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-3 family.|||Cytoplasm|||IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS01245 ^@ http://purl.uniprot.org/uniprot/G0EHS7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS06830 ^@ http://purl.uniprot.org/uniprot/G0EPT7 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Cell membrane|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Membrane|||Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane. http://togogenome.org/gene/1045858:BINT_RS07795 ^@ http://purl.uniprot.org/uniprot/G0EI41 ^@ Function|||Similarity ^@ Belongs to the ribonucleoside diphosphate reductase large chain family.|||Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. http://togogenome.org/gene/1045858:BINT_RS06575 ^@ http://purl.uniprot.org/uniprot/G0EP74 ^@ Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.|||Binds 1 potassium ion per subunit.|||Cytoplasm|||Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.|||Homodimer. Heterotetramer of two MnmE and two MnmG subunits.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS03515 ^@ http://purl.uniprot.org/uniprot/G0EKF0 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/1045858:BINT_RS08145 ^@ http://purl.uniprot.org/uniprot/G0EIR6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS12225 ^@ http://purl.uniprot.org/uniprot/G0ENC8 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase gamma chain family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. http://togogenome.org/gene/1045858:BINT_RS01525 ^@ http://purl.uniprot.org/uniprot/G0EHY2 ^@ Similarity|||Subunit ^@ Belongs to the NAD(P)-dependent epimerase/dehydratase family.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS12545 ^@ http://purl.uniprot.org/uniprot/G0ENS1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL4 family.|||Forms part of the polypeptide exit tunnel.|||One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS05020 ^@ http://purl.uniprot.org/uniprot/G0EM63 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliE family. http://togogenome.org/gene/1045858:BINT_RS07295 ^@ http://purl.uniprot.org/uniprot/G0EQJ4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12560 ^@ http://purl.uniprot.org/uniprot/G0ENS4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.|||Cytoplasm|||Monomer.|||This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. http://togogenome.org/gene/1045858:BINT_RS08335 ^@ http://purl.uniprot.org/uniprot/G0EIV6 ^@ Similarity ^@ Belongs to the inositol monophosphatase superfamily. http://togogenome.org/gene/1045858:BINT_RS13040 ^@ http://purl.uniprot.org/uniprot/G0EPH6 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the SmpB family.|||Cytoplasm|||Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation. http://togogenome.org/gene/1045858:BINT_RS00170 ^@ http://purl.uniprot.org/uniprot/G0ENZ7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12185 ^@ http://purl.uniprot.org/uniprot/G0ENC0 ^@ Cofactor|||Similarity ^@ Belongs to the RtcB family.|||Binds 2 manganese ions per subunit. http://togogenome.org/gene/1045858:BINT_RS08055 ^@ http://purl.uniprot.org/uniprot/G0EIP8 ^@ Function|||Similarity ^@ Belongs to the dus family.|||Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. http://togogenome.org/gene/1045858:BINT_RS01360 ^@ http://purl.uniprot.org/uniprot/G0EHV0 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the LemA family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12305 ^@ http://purl.uniprot.org/uniprot/G0ENE4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the helicase family. PriA subfamily.|||Component of the primosome.|||Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA. http://togogenome.org/gene/1045858:BINT_RS06770 ^@ http://purl.uniprot.org/uniprot/G0EPB5 ^@ Function|||Similarity ^@ Belongs to the aspartate/glutamate racemases family.|||Provides the (R)-glutamate required for cell wall biosynthesis. http://togogenome.org/gene/1045858:BINT_RS06460 ^@ http://purl.uniprot.org/uniprot/G0EP52 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS05035 ^@ http://purl.uniprot.org/uniprot/G0EM66 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the MscS (TC 1.A.23) family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS08100 ^@ http://purl.uniprot.org/uniprot/G0EIQ7 ^@ Similarity ^@ Belongs to the peptidase U62 family. http://togogenome.org/gene/1045858:BINT_RS02465 ^@ http://purl.uniprot.org/uniprot/G0EJD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the CobD/CbiB family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS11780 ^@ http://purl.uniprot.org/uniprot/G0EMV6 ^@ Similarity ^@ Belongs to the helicase family. RecG subfamily. http://togogenome.org/gene/1045858:BINT_RS11585 ^@ http://purl.uniprot.org/uniprot/G0EMR8 ^@ Function|||PTM|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL11 family.|||Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.|||One or more lysine residues are methylated.|||Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex. http://togogenome.org/gene/1045858:BINT_RS03340 ^@ http://purl.uniprot.org/uniprot/G0EKB5 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 3 family. http://togogenome.org/gene/1045858:BINT_RS10450 ^@ http://purl.uniprot.org/uniprot/G0ELF6 ^@ Similarity ^@ Belongs to the ribF family. http://togogenome.org/gene/1045858:BINT_RS08350 ^@ http://purl.uniprot.org/uniprot/G0EIV9 ^@ Cofactor ^@ Binds 1 zinc ion per subunit. http://togogenome.org/gene/1045858:BINT_RS06370 ^@ http://purl.uniprot.org/uniprot/G0ENM5 ^@ Similarity ^@ Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. http://togogenome.org/gene/1045858:BINT_RS03475 ^@ http://purl.uniprot.org/uniprot/G0EKE2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS00725 ^@ http://purl.uniprot.org/uniprot/G0EPS1 ^@ Similarity ^@ Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily. http://togogenome.org/gene/1045858:BINT_RS04815 ^@ http://purl.uniprot.org/uniprot/G0EM24 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 9 family. http://togogenome.org/gene/1045858:BINT_RS14195 ^@ http://purl.uniprot.org/uniprot/G0EIB6 ^@ Function|||Miscellaneous|||Similarity ^@ Belongs to the thiamine-monophosphate kinase family.|||Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.|||Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate. http://togogenome.org/gene/1045858:BINT_RS03420 ^@ http://purl.uniprot.org/uniprot/G0EKD1 ^@ Similarity ^@ Belongs to the UPF0145 family. http://togogenome.org/gene/1045858:BINT_RS06995 ^@ http://purl.uniprot.org/uniprot/G0EPX2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS13680 ^@ http://purl.uniprot.org/uniprot/G0EQS7 ^@ Function|||Similarity|||Subunit ^@ Belongs to the DnaX/STICHEL family.|||DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.|||DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. http://togogenome.org/gene/1045858:BINT_RS07340 ^@ http://purl.uniprot.org/uniprot/G0EQK3 ^@ Caution|||Function|||Similarity ^@ Belongs to the NAD synthetase family.|||Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.|||In the C-terminal section; belongs to the NAD synthetase family.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS03805 ^@ http://purl.uniprot.org/uniprot/G0EKT8 ^@ Similarity ^@ Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS13255 ^@ http://purl.uniprot.org/uniprot/G0EQ30 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the TER reductase family.|||Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS05725 ^@ http://purl.uniprot.org/uniprot/G0EN11 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS04320 ^@ http://purl.uniprot.org/uniprot/G0ELB7 ^@ Similarity ^@ Belongs to the phosphohexose mutase family. http://togogenome.org/gene/1045858:BINT_RS12445 ^@ http://purl.uniprot.org/uniprot/G0ENQ1 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the IF-1 family.|||Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.|||Cytoplasm|||One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. http://togogenome.org/gene/1045858:BINT_RS07690 ^@ http://purl.uniprot.org/uniprot/G0EI20 ^@ Similarity ^@ Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. http://togogenome.org/gene/1045858:BINT_RS06215 ^@ http://purl.uniprot.org/uniprot/G0ENJ4 ^@ Function|||Similarity ^@ Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.|||Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate. http://togogenome.org/gene/1045858:BINT_RS03470 ^@ http://purl.uniprot.org/uniprot/G0EKE1 ^@ Similarity ^@ Belongs to the sulfur carrier protein TusA family. http://togogenome.org/gene/1045858:BINT_RS08775 ^@ http://purl.uniprot.org/uniprot/G0EJJ7 ^@ Similarity ^@ Belongs to the 5'-nucleotidase family. http://togogenome.org/gene/1045858:BINT_RS11675 ^@ http://purl.uniprot.org/uniprot/G0EMT5 ^@ Similarity ^@ Belongs to the acylphosphatase family. http://togogenome.org/gene/1045858:BINT_RS13280 ^@ http://purl.uniprot.org/uniprot/G0EQ36 ^@ Similarity ^@ Belongs to the UPF0102 family. http://togogenome.org/gene/1045858:BINT_RS10500 ^@ http://purl.uniprot.org/uniprot/G0ELG5 ^@ Function|||Similarity ^@ Belongs to the KptA/TPT1 family.|||Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''-cyclic phosphate (APPR>P). May function as an ADP-ribosylase. http://togogenome.org/gene/1045858:BINT_RS01935 ^@ http://purl.uniprot.org/uniprot/G0EIM0 ^@ Similarity ^@ Belongs to the class-I fumarase family. http://togogenome.org/gene/1045858:BINT_RS11610 ^@ http://purl.uniprot.org/uniprot/G0EMS2 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10115 ^@ http://purl.uniprot.org/uniprot/G0EL07 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS05010 ^@ http://purl.uniprot.org/uniprot/G0EM61 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.|||The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod. http://togogenome.org/gene/1045858:BINT_RS04700 ^@ http://purl.uniprot.org/uniprot/G0ELR9 ^@ Similarity|||Subcellular Location Annotation|||Subunit ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family.|||The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each. http://togogenome.org/gene/1045858:BINT_RS01450 ^@ http://purl.uniprot.org/uniprot/G0EHW8 ^@ Similarity ^@ Belongs to the BMP lipoprotein family. http://togogenome.org/gene/1045858:BINT_RS02670 ^@ http://purl.uniprot.org/uniprot/G0EJG9 ^@ Cofactor|||Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.|||Binds 1 zinc ion per subunit.|||Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).|||Cytoplasm|||IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).|||Monomer. http://togogenome.org/gene/1045858:BINT_RS08400 ^@ http://purl.uniprot.org/uniprot/G0EJ47 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the MurCDEF family.|||Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS07290 ^@ http://purl.uniprot.org/uniprot/G0EQJ3 ^@ Caution|||Function|||Similarity ^@ Belongs to the DXR family.|||Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS13985 ^@ http://purl.uniprot.org/uniprot/G0EI79 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the EPSP synthase family. MurA subfamily.|||Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS02060 ^@ http://purl.uniprot.org/uniprot/G0EIX4 ^@ Caution|||Cofactor|||Function|||Similarity ^@ Binds 1 FMN per subunit.|||Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.|||Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.|||In the C-terminal section; belongs to the PPC synthetase family.|||In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS13980 ^@ http://purl.uniprot.org/uniprot/G0EI78 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the flagella basal body rod proteins family. http://togogenome.org/gene/1045858:BINT_RS10070 ^@ http://purl.uniprot.org/uniprot/G0EKZ7 ^@ Function|||Similarity ^@ Belongs to the carbohydrate kinase PfkB family.|||Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate. http://togogenome.org/gene/1045858:BINT_RS04790 ^@ http://purl.uniprot.org/uniprot/G0ELT8 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS11805 ^@ http://purl.uniprot.org/uniprot/G0EMW1 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS02920 ^@ http://purl.uniprot.org/uniprot/G0EJU9 ^@ Function ^@ Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. http://togogenome.org/gene/1045858:BINT_RS14235 ^@ http://purl.uniprot.org/uniprot/G0EIC4 ^@ Caution|||Function|||Similarity ^@ Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.|||Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS03520 ^@ http://purl.uniprot.org/uniprot/G0EKF1 ^@ Similarity ^@ Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family. http://togogenome.org/gene/1045858:BINT_RS04360 ^@ http://purl.uniprot.org/uniprot/G0ELC5 ^@ Similarity ^@ Belongs to the UPF0597 family. http://togogenome.org/gene/1045858:BINT_RS02925 ^@ http://purl.uniprot.org/uniprot/G0EJV0 ^@ Function|||Similarity ^@ Belongs to the sigma-70 factor family.|||Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. http://togogenome.org/gene/1045858:BINT_RS01650 ^@ http://purl.uniprot.org/uniprot/G0EIG3 ^@ Similarity ^@ Belongs to the UPF0047 family. http://togogenome.org/gene/1045858:BINT_RS08030 ^@ http://purl.uniprot.org/uniprot/G0EIP3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the acetylglutamate kinase family. ArgB subfamily.|||Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS12495 ^@ http://purl.uniprot.org/uniprot/G0ENR1 ^@ Function|||Similarity|||Subunit ^@ Belongs to the universal ribosomal protein uL24 family.|||One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.|||One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.|||Part of the 50S ribosomal subunit. http://togogenome.org/gene/1045858:BINT_RS03165 ^@ http://purl.uniprot.org/uniprot/G0EJZ9 ^@ Similarity ^@ Belongs to the N(4)/N(6)-methyltransferase family. http://togogenome.org/gene/1045858:BINT_RS00780 ^@ http://purl.uniprot.org/uniprot/G0EPT1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the D-alanine--D-alanine ligase family.|||Binds 2 magnesium or manganese ions per subunit.|||Cell wall formation.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS13660 ^@ http://purl.uniprot.org/uniprot/G0EQS3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase A8 family.|||Cell inner membrane|||This protein specifically catalyzes the removal of signal peptides from prolipoproteins. http://togogenome.org/gene/1045858:BINT_RS12330 ^@ http://purl.uniprot.org/uniprot/G0ENE9 ^@ Function|||Similarity ^@ Belongs to the GHMP kinase family. IspE subfamily.|||Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. http://togogenome.org/gene/1045858:BINT_RS11320 ^@ http://purl.uniprot.org/uniprot/G0EMD2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family.|||Cell membrane http://togogenome.org/gene/1045858:BINT_RS13695 ^@ http://purl.uniprot.org/uniprot/G0EQT0 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS13500 ^@ http://purl.uniprot.org/uniprot/G0EQ79 ^@ Activity Regulation|||Function|||Similarity ^@ Belongs to the FGGY kinase family.|||Inhibited by fructose 1,6-bisphosphate (FBP).|||Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate. http://togogenome.org/gene/1045858:BINT_RS05470 ^@ http://purl.uniprot.org/uniprot/G0EMN2 ^@ Caution|||Function|||Similarity|||Subunit ^@ Belongs to the IPP transferase family.|||Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Monomer. http://togogenome.org/gene/1045858:BINT_RS00185 ^@ http://purl.uniprot.org/uniprot/G0EP00 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the nlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS14155 ^@ http://purl.uniprot.org/uniprot/G0EIA7 ^@ Similarity ^@ Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS14270 ^@ http://purl.uniprot.org/uniprot/G0EID2 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS13735 ^@ http://purl.uniprot.org/uniprot/G0EQT8 ^@ Similarity ^@ Belongs to the ETF alpha-subunit/FixB family. http://togogenome.org/gene/1045858:BINT_RS00180 ^@ http://purl.uniprot.org/uniprot/G0ENZ9 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the NlpA lipoprotein family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS10355 ^@ http://purl.uniprot.org/uniprot/G0EL57 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the gamma-glutamyl phosphate reductase family.|||Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS09500 ^@ http://purl.uniprot.org/uniprot/G0EK72 ^@ Function|||Similarity ^@ Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.|||Synthesizes alpha-1,4-glucan chains using ADP-glucose. http://togogenome.org/gene/1045858:BINT_RS07225 ^@ http://purl.uniprot.org/uniprot/G0EQI0 ^@ Function|||Similarity ^@ Belongs to the vitamin-B12 dependent methionine synthase family.|||Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. http://togogenome.org/gene/1045858:BINT_RS03500 ^@ http://purl.uniprot.org/uniprot/G0EKE7 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase S26 family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS09115 ^@ http://purl.uniprot.org/uniprot/G0EJR4 ^@ Function|||Similarity|||Subunit ^@ Belongs to the TrpB family.|||Tetramer of two alpha and two beta chains.|||The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine. http://togogenome.org/gene/1045858:BINT_RS10350 ^@ http://purl.uniprot.org/uniprot/G0EL56 ^@ Similarity ^@ Belongs to the methyltransferase superfamily. PrmA family. http://togogenome.org/gene/1045858:BINT_RS08680 ^@ http://purl.uniprot.org/uniprot/G0EJ99 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS03660 ^@ http://purl.uniprot.org/uniprot/G0EKQ8 ^@ Cofactor ^@ Binds 1 Mg(2+) ion per trimer. http://togogenome.org/gene/1045858:BINT_RS02275 ^@ http://purl.uniprot.org/uniprot/G0EJ15 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliM family.|||Cell inner membrane|||FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.|||Membrane http://togogenome.org/gene/1045858:BINT_RS03655 ^@ http://purl.uniprot.org/uniprot/G0EKQ7 ^@ Similarity ^@ Belongs to the bacterial solute-binding protein 5 family. http://togogenome.org/gene/1045858:BINT_RS04290 ^@ http://purl.uniprot.org/uniprot/G0ELB1 ^@ Similarity ^@ Belongs to the thioredoxin family. http://togogenome.org/gene/1045858:BINT_RS08960 ^@ http://purl.uniprot.org/uniprot/G0EJN3 ^@ Similarity ^@ Belongs to the type-I restriction system S methylase family. http://togogenome.org/gene/1045858:BINT_RS05485 ^@ http://purl.uniprot.org/uniprot/G0EMN5 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum basal body|||Belongs to the FliF family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS12015 ^@ http://purl.uniprot.org/uniprot/G0EN87 ^@ Similarity ^@ Belongs to the KHG/KDPG aldolase family. http://togogenome.org/gene/1045858:BINT_RS05265 ^@ http://purl.uniprot.org/uniprot/G0EMJ1 ^@ Function|||Similarity ^@ Belongs to the RecN family.|||May be involved in recombinational repair of damaged DNA. http://togogenome.org/gene/1045858:BINT_RS12255 ^@ http://purl.uniprot.org/uniprot/G0END4 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase A chain family.|||Cell inner membrane|||Cell membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.|||Membrane http://togogenome.org/gene/1045858:BINT_RS05330 ^@ http://purl.uniprot.org/uniprot/G0EMK4 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the ferritin family. Prokaryotic subfamily.|||Cytoplasm|||Iron-storage protein. http://togogenome.org/gene/1045858:BINT_RS11195 ^@ http://purl.uniprot.org/uniprot/G0EMA7 ^@ Function|||Similarity ^@ Belongs to the glycogen phosphorylase family.|||Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. http://togogenome.org/gene/1045858:BINT_RS05370 ^@ http://purl.uniprot.org/uniprot/G0EML2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the pyrroline-5-carboxylate reductase family.|||Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS11560 ^@ http://purl.uniprot.org/uniprot/G0EMR3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the RNA polymerase beta' chain family.|||Binds 1 Mg(2+) ion per subunit.|||Binds 2 Zn(2+) ions per subunit.|||DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.|||The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription. http://togogenome.org/gene/1045858:BINT_RS07440 ^@ http://purl.uniprot.org/uniprot/G0EQM4 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS10100 ^@ http://purl.uniprot.org/uniprot/G0EL03 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS06235 ^@ http://purl.uniprot.org/uniprot/G0ENJ8 ^@ Subcellular Location Annotation ^@ Mitochondrion http://togogenome.org/gene/1045858:BINT_RS14210 ^@ http://purl.uniprot.org/uniprot/G0EIB9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.|||Binds 2 [4Fe-4S] clusters per subunit.|||Cell inner membrane|||Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.|||The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG. http://togogenome.org/gene/1045858:BINT_RS02795 ^@ http://purl.uniprot.org/uniprot/G0EJJ3 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.|||Cytoplasm|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Specifically methylates the N7 position of a guanine in 16S rRNA. http://togogenome.org/gene/1045858:BINT_RS08180 ^@ http://purl.uniprot.org/uniprot/G0EIS4 ^@ Cofactor|||Similarity ^@ Belongs to the peptidase M42 family.|||Binds 2 divalent metal cations per subunit. http://togogenome.org/gene/1045858:BINT_RS08800 ^@ http://purl.uniprot.org/uniprot/G0EJK2 ^@ Similarity ^@ Belongs to the bacterial ribosomal protein bL35 family. http://togogenome.org/gene/1045858:BINT_RS07805 ^@ http://purl.uniprot.org/uniprot/G0EI43 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.|||Membrane http://togogenome.org/gene/1045858:BINT_RS10650 ^@ http://purl.uniprot.org/uniprot/G0ELJ4 ^@ Function|||Similarity ^@ Belongs to the DNA mismatch repair MutS family.|||This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. http://togogenome.org/gene/1045858:BINT_RS01740 ^@ http://purl.uniprot.org/uniprot/G0EII1 ^@ Similarity ^@ Belongs to the thymidylate kinase family. http://togogenome.org/gene/1045858:BINT_RS01380 ^@ http://purl.uniprot.org/uniprot/G0EHV4 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the peptidase M50B family.|||Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS12090 ^@ http://purl.uniprot.org/uniprot/G0ENA2 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the elongation factor P family.|||Cytoplasm|||Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. http://togogenome.org/gene/1045858:BINT_RS03410 ^@ http://purl.uniprot.org/uniprot/G0EKC9 ^@ Similarity ^@ Belongs to the LOG family. http://togogenome.org/gene/1045858:BINT_RS00165 ^@ http://purl.uniprot.org/uniprot/G0ENZ6 ^@ Caution|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the LDH/MDH superfamily. LDH family.|||Catalyzes the conversion of lactate to pyruvate.|||Cytoplasm|||Homotetramer.|||Lacks conserved residue(s) required for the propagation of feature annotation. http://togogenome.org/gene/1045858:BINT_RS01045 ^@ http://purl.uniprot.org/uniprot/G0EQE4 ^@ Similarity ^@ Belongs to the methyl-accepting chemotaxis (MCP) protein family. http://togogenome.org/gene/1045858:BINT_RS11520 ^@ http://purl.uniprot.org/uniprot/G0EMH4 ^@ Similarity ^@ Belongs to the pseudouridine synthase RsuA family. http://togogenome.org/gene/1045858:BINT_RS08205 ^@ http://purl.uniprot.org/uniprot/G0EIS9 ^@ Function|||Similarity ^@ Belongs to the type-2 OGG1 family.|||Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). http://togogenome.org/gene/1045858:BINT_RS11630 ^@ http://purl.uniprot.org/uniprot/G0EMS6 ^@ Activity Regulation|||Caution|||Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.|||Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.|||Belongs to the carbohydrate kinase pfkB family.|||Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.|||Cytoplasm|||Homodimer.|||Lacks conserved residue(s) required for the propagation of feature annotation.|||Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate. http://togogenome.org/gene/1045858:BINT_RS04530 ^@ http://purl.uniprot.org/uniprot/G0ELN5 ^@ Similarity ^@ Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. http://togogenome.org/gene/1045858:BINT_RS13855 ^@ http://purl.uniprot.org/uniprot/G0EQW2 ^@ Similarity ^@ Belongs to the hemerythrin family. http://togogenome.org/gene/1045858:BINT_RS13745 ^@ http://purl.uniprot.org/uniprot/G0EQU0 ^@ Similarity ^@ Belongs to the acyl-CoA dehydrogenase family. http://togogenome.org/gene/1045858:BINT_RS03570 ^@ http://purl.uniprot.org/uniprot/G0EKG0 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.|||Binds 2 Mg(2+) ions per subunit.|||Cytoplasm|||Homohexamer.|||Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P). http://togogenome.org/gene/1045858:BINT_RS12905 ^@ http://purl.uniprot.org/uniprot/G0EPE8 ^@ Similarity|||Subcellular Location Annotation ^@ Belongs to the OXA1/ALB3/YidC family.|||Membrane http://togogenome.org/gene/1045858:BINT_RS11305 ^@ http://purl.uniprot.org/uniprot/G0EMC9 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the phosphopentomutase family.|||Binds 1 or 2 manganese ions.|||Cytoplasm|||Phosphotransfer between the C1 and C5 carbon atoms of pentose. http://togogenome.org/gene/1045858:BINT_RS14280 ^@ http://purl.uniprot.org/uniprot/G0EID4 ^@ Similarity|||Subcellular Location Annotation ^@ Bacterial flagellum|||Belongs to the flagella basal body rod proteins family.|||Secreted http://togogenome.org/gene/1045858:BINT_RS08035 ^@ http://purl.uniprot.org/uniprot/G0EIP4 ^@ Cofactor|||Miscellaneous|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.|||Binds 1 pyridoxal phosphate per subunit.|||Cytoplasm|||Homodimer.|||May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis. http://togogenome.org/gene/1045858:BINT_RS04415 ^@ http://purl.uniprot.org/uniprot/G0ELD6 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ribonuclease III family.|||Cytoplasm|||Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.|||Homodimer. http://togogenome.org/gene/1045858:BINT_RS01265 ^@ http://purl.uniprot.org/uniprot/G0EHT1 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the thiolase-like superfamily. FabH family.|||Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.|||Cytoplasm|||Homodimer.|||The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH. http://togogenome.org/gene/1045858:BINT_RS13710 ^@ http://purl.uniprot.org/uniprot/G0EQT3 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/1045858:BINT_RS04765 ^@ http://purl.uniprot.org/uniprot/G0ELT3 ^@ Cofactor|||Function|||Similarity|||Subunit ^@ Belongs to the pseudouridine-5'-phosphate glycosidase family.|||Binds 1 Mn(2+) ion per subunit.|||Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.|||Homotrimer. http://togogenome.org/gene/1045858:BINT_RS08235 ^@ http://purl.uniprot.org/uniprot/G0EIT6 ^@ Subcellular Location Annotation ^@ Membrane http://togogenome.org/gene/1045858:BINT_RS02430 ^@ http://purl.uniprot.org/uniprot/G0EJC4 ^@ Domain|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the tRNA(Ile)-lysidine synthase family.|||Cytoplasm|||Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.|||The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding. http://togogenome.org/gene/1045858:BINT_RS13715 ^@ http://purl.uniprot.org/uniprot/G0EQT4 ^@ Similarity ^@ Belongs to the ATPase alpha/beta chains family. http://togogenome.org/gene/1045858:BINT_RS13075 ^@ http://purl.uniprot.org/uniprot/G0EPI4 ^@ Subcellular Location Annotation ^@ Cell membrane|||Membrane http://togogenome.org/gene/1045858:BINT_RS01475 ^@ http://purl.uniprot.org/uniprot/G0EHX3 ^@ Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.|||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS03070 ^@ http://purl.uniprot.org/uniprot/G0EJY1 ^@ Cofactor|||Function|||Similarity|||Subcellular Location Annotation ^@ Belongs to the methylthiotransferase family. RimO subfamily.|||Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.|||Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.|||Cytoplasm http://togogenome.org/gene/1045858:BINT_RS07895 ^@ http://purl.uniprot.org/uniprot/G0EI59 ^@ Similarity ^@ Belongs to the bacterial microcompartments protein family. http://togogenome.org/gene/1045858:BINT_RS12230 ^@ http://purl.uniprot.org/uniprot/G0ENC9 ^@ Function|||Similarity|||Subcellular Location Annotation|||Subunit ^@ Belongs to the ATPase alpha/beta chains family.|||Cell inner membrane|||F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a(1), b(2) and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF(1) is attached to CF(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.|||Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.