Helical; Signal-anchor for type II membrane protein
Hydroxyacylglutathione hydrolase, mitochondrial
Arylamine N-acetyltransferase, pineal gland isozyme NAT-10
POU domain, class 2, transcription factor 1
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)
N6-(2-hydroxyisobutyryl)lysine; alternate
Eukaryotic translation initiation factor 2A
Basic helix-loop-helix ARNT-like protein 1
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2 and SUMO3)
Transforming growth factor-beta-induced protein ig-h3
Ubiquitin-like domain-containing CTD phosphatase 1
Beta-galactoside alpha-2,6-sialyltransferase 1
Increased sister chromatid exchanges. No effect on FANCD2 monoubiquitination, nor on cisplatin sensitivity.
ADP-ribosylation factor-like protein 6-interacting protein 4
Hematopoietically-expressed homeobox protein HHEX
Glucose-induced degradation protein 8 homolog
ATP synthase subunit beta, mitochondrial
glycerophosphocholine cholinephosphodiesterase
Interchain (between light and heavy chains)
Cysteine-rich DPF motif domain-containing protein 1
Actin, alpha skeletal muscle, intermediate form
N-acetylaspartate; in Actin, alpha skeletal muscle
High mobility group nucleosome-binding domain-containing protein 3
Translocon-associated protein subunit alpha
Complete loss of binding to VTG2 promoter in isoform 3.
Iron-sulfur cluster assembly 1 homolog, mitochondrial
U3 small nucleolar RNA-associated protein 25 homolog
V-set and immunoglobulin domain-containing protein 1
Myosin heavy chain, skeletal muscle, adult
High affinity immunoglobulin epsilon receptor subunit gamma
Rho guanine nucleotide exchange factor 3
Serine/threonine-protein phosphatase 4 regulatory subunit 2
CCHC-type zinc finger nucleic acid binding protein
Adipocyte plasma membrane-associated protein
Lower thermal denaturation temperature, more susceptible to elastase or subtilisin cleavage and assumes a native-like conformation on alkaline treatment; when associated with or without A-121.
Lower thermal denaturation temperature, more susceptible to elastase or subtilisin cleavage and assumes a native-like conformation on alkaline treatment; when associated with or without A-74.
Significantly more thermostabilized following cleavage at P-P' site. Inserts reactive loop at very slow rate. No inhibitory action against serine proteinases.
Platelet-activating factor acetylhydrolase
Endoplasmic reticulum resident protein 29
Fibroblast growth factor receptor-like 1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
Nuclear distribution protein nudE-like 1
Tumor necrosis factor receptor superfamily member 1B
Phosphatidylinositol 4-phosphate 5-kinase type-1 beta
Receptor-type tyrosine-protein phosphatase eta
Mediator of RNA polymerase II transcription subunit 17
Solute carrier family 2, facilitated glucose transporter member 1
Charge relay system; for autoendoproteolytic cleavage activity
Phosphatidylserine decarboxylase alpha chain
Phosphatidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity
LHFPL tetraspan subfamily member 5 protein
Parathyroid hormone/parathyroid hormone-related peptide receptor
Interchain (between heavy and light chains)
Beta-galactoside alpha-2,6-sialyltransferase 2
Photoreceptor outer segment membrane glycoprotein 2
ATP-dependent (S)-NAD(P)H-hydrate dehydratase
Leucine-rich repeat-containing protein 40
Ubiquitin carboxyl-terminal hydrolase 28
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1
N-acetylglucosaminylphosphatidylinositol deacetylase
Sigma non-opioid intracellular receptor 1
Zinc finger Ran-binding domain-containing protein 2
Cysteinyl-selenocysteine (Cys-Sec); redox-active
N-linked (GlcNAc...) (keratan sulfate) asparagine
Serine/threonine-protein kinase 4 18kDa subunit
Serine/threonine-protein kinase 4 37kDa subunit
Store-operated calcium entry-associated regulatory factor
Low-density lipoprotein receptor-related protein 1
Recognition site for proteolytical processing
Asymmetric dimethylarginine; by CARM1; alternate
Asymmetric dimethylarginine; by PRMT6; alternate
Phosphoserine; alternate; by AURKB, AURKC and RPS6KA5
Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5
Symmetric dimethylarginine; by PRMT5; alternate
Disintegrin and metalloproteinase domain-containing protein 10
Cerebellar degeneration-related protein 2
Platelet-derived growth factor receptor-like protein
Musculoskeletal embryonic nuclear protein 1
Immediate early response 3-interacting protein 1
Heterogeneous nuclear ribonucleoprotein D-like
U4/U6 small nuclear ribonucleoprotein Prp3
Histone-lysine N-methyltransferase SETD1B
Basic helix-loop-helix transcription factor scleraxis
Coiled-coil domain-containing protein 43
NAD-dependent protein deacylase sirtuin-5, mitochondrial
WD repeat and coiled-coil-containing protein
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Brain-specific homeobox/POU domain protein 3
Proheparin-binding EGF-like growth factor
Hydroxyacylglutathione hydrolase-like protein
O-(5'-phospho-DNA)-tyrosine intermediate
Asymmetric dimethylarginine; by PRMT1; alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate
Omega-N-methylarginine; by PRMT1; alternate
Symmetric dimethylarginine; by PRMT5 and PRMT7; alternate
Ligand-dependent nuclear receptor corepressor-like protein
CCR4-NOT transcription complex subunit 10
Telomeric repeat-binding factor 2-interacting protein 1
Asparagine synthetase [glutamine-hydrolyzing]
Multiple inositol polyphosphate phosphatase 1
Two-fold greater substrate affinity and doubling of catalytic activity.
V-type proton ATPase catalytic subunit A
Schiff-base intermediate with dihydroxyacetone-P
Solute carrier family 2, facilitated glucose transporter member 3
cAMP-dependent protein kinase type I-alpha regulatory subunit
Protein-L-isoaspartate O-methyltransferase domain-containing protein 1
Abolishes homodimerization and up-regulation of NOG mRNA levels. Loss of function in gastrointestinal smooth muscle cell differentiation and in gastrointestinal smooth muscle development.
RNA-binding protein with multiple splicing 2
Uncharacterized protein KIAA1671 homolog
Proto-oncogene tyrosine-protein kinase Yrk
Insulin-like growth factor-binding protein 4
Helical; Voltage-sensor; Name=Segment S4
Potassium voltage-gated channel subfamily G member 2
Zinc finger CCCH domain-containing protein 11A
GTPase-activating Rap/Ran-GAP domain-like protein 3
Insulin-like growth factor-binding protein 5
Actin, gamma-enteric smooth muscle, intermediate form
N-acetylglutamate; in Actin, gamma-enteric smooth muscle
Serine/arginine repetitive matrix protein 1
Decreases transcriptional activity at low hormone concentration. Does not alter hormone binding affinity.
Decreases transcriptional activity independently of hormone concentration. Does not alter hormone binding affinity.
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO); alternate
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1)
Gamma-aminobutyric acid receptor subunit gamma-2
Small nuclear ribonucleoprotein-associated protein B'
Alpha-1,6-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
BMP and activin membrane-bound inhibitor homolog
Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial
T-cell acute lymphocytic leukemia protein 1 homolog
Sodium/potassium-transporting ATPase subunit beta-1
Membrane-associated progesterone receptor component 1
BMP/retinoic acid-inducible neural-specific protein 1
N-linked (GlcNAc...) (complex) asparagine
NAD(P)(+)--arginine ADP-ribosyltransferase 2
RNA polymerase II subunit A C-terminal domain phosphatase SSU72
2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial
Serine-threonine kinase receptor-associated protein
ADP-ribosylasparagine; by botulinum toxin
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2
Acyl-CoA-binding domain-containing protein 5
RAF proto-oncogene serine/threonine-protein kinase
NmrA-like family domain-containing protein 1
Coiled-coil domain-containing protein 50
Phosphatidylserine amidated glycine; alternate
General transcription factor IIH subunit 5
Probable glutamate--tRNA ligase, mitochondrial
Proton acceptor; for processing activity
Schiff-base intermediate with substrate; via pyruvic acid
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'
Proto-oncogene tyrosine-protein kinase Src
Significant reduction in S-nitrosylation.
Cilia- and flagella-associated protein 20
receptor protein serine/threonine kinase
Ubiquitin-like modifier-activating enzyme ATG7
Heterochromatin protein 1-binding protein 3
Transcription initiation factor TFIID subunit 8
Leucine-rich repeat transmembrane protein FLRT3
Trafficking protein particle complex subunit 11
Lysosome-associated membrane glycoprotein 1
Beta-1,3-N-acetylglucosaminyltransferase radical fringe
Glycine amidinotransferase, mitochondrial
Translocon-associated protein subunit beta
GDP-fucose protein O-fucosyltransferase 1
NF-kappa-B inhibitor-interacting Ras-like protein 2
DNA-directed RNA polymerase III subunit RPC1
Low-density lipoprotein receptor-related protein 8
Abolishes sumoylation; when associated with A-181. Abolishes phosphorylation; when associated with A-181. Reduces ability to associate with UBE2I; when associated with A-181. Prevents trunk neural crest delamination; when associated with A-181. Prevents cooperating with SNAI2 to trigger neural crest delamination; when associated with A-181. Abolishes interaction with SNAI2; when associated with A-181.
Abolishes sumoylation; when associated with A-64. Abolishes phosphorylation; when associated with A-64. Reduces ability to associate with UBE2I; when associated with A-64. Prevents trunk neural crest delamination; when associated with A-64. Prevents cooperating with SNAI2 to trigger neural crest delamination; when associated with A-64. Abolishes interaction with SNAI2; when associated with A-64.
Decreases cooperating with SNAI2 to trigger neural crest delamination; when associated with R-254 and R-376.
Decreases cooperating with SNAI2 to trigger neural crest delamination; when associated with R-61 and R-254.
Decreases cooperating with SNAI2 to trigger neural crest delamination; when associated with R-61 and R-376.
Sumoylation; when associated with D-181. Initiates trunk neural crest delamination; when associated with D-181. Allows cooperating with SNAI2 to trigger neural crest delamination; when associated with D-181. Allows interaction with SNAI2; when associated with D-181.
Sumoylation; when associated with D-64. Initiates trunk neural crest delamination; when associated with D-64. Allows cooperating with SNAI2 to trigger neural crest delamination; when associated with D-64. Allows interaction with SNAI2; when associated with D-64.
Activating signal cointegrator 1 complex subunit 3
Queuine tRNA-ribosyltransferase accessory subunit 2
Histone-lysine N-methyltransferase SUV39H2
Fibronectin type-III domain-containing protein 3a
Increases binding of hyaluronan and heparin.
Interphotoreceptor matrix proteoglycan 1
No effect on binding of hyaluronan or heparin.
Reduces binding of hyaluronan and heparin.
Cell division control protein 42 homolog
V(D)J recombination-activating protein 1
Natural resistance-associated macrophage protein 1
Urokinase-type plasminogen activator chain A
Urokinase-type plasminogen activator chain B
Nuclear receptor subfamily 5 group A member 2
Mediator of RNA polymerase II transcription subunit 20
Eukaryotic translation initiation factor 3 subunit J
Cell surface glycoprotein CD200 receptor 1-A
Sister chromatid cohesion protein PDS5 homolog A
Bone morphogenetic protein receptor type-1B
Loss of positive regulation of chondrocyte differentiation.
Strongly decreases positive regulation of chondrocyte differentiation.
Helical; Anchor for type IV membrane protein
Trimethyllysine dioxygenase, mitochondrial
N-linked (GlcNAc...) asparagine; partial
Phosphatidylinositol-glycan-specific phospholipase D
Pleckstrin homology domain-containing family F member 2
Schiff-base intermediate with DNA; for 5'-deoxyribose-5-phosphate lyase activity
X-ray repair cross-complementing protein 5
Activated RNA polymerase II transcriptional coactivator p15
ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyldiphosphate specific]
O-linked (Xyl...) (heparan sulfate) serine
Coiled-coil domain-containing protein 80
Lysosomal-associated transmembrane protein 4A
Low molecular weight phosphotyrosine protein phosphatase
Protein-glucosylgalactosylhydroxylysine glucosidase
Abolishes interaction with SRC SH3 domain and decreases tyrosine phosphorylation.
Reduces phosphorylation and abolishes interaction with activated SRC; when associated with A-93; A-451 and A-453.
Reduces phosphorylation and abolishes interaction with activated SRC; when associated with A-93; A-94 and A-451.
Reduces phosphorylation and abolishes interaction with activated SRC; when associated with A-94; A-451 and A-453.
Breast cancer metastasis-suppressor 1-like protein
Phosphatidylinositol 4-kinase type 2-beta
Ubiquitin-like modifier-activating enzyme 5
Guanine nucleotide-binding protein G(i) subunit alpha-1
NPC intracellular cholesterol transporter 2
Transcription termination factor 3, mitochondrial
In strain: 16, 17, 25, 7, Black Minorca, Fayoumi GSP, WL-F and WL-N.
In strain: 16, 17, 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N.
In strain: 16, 17, 25, Black Minorca, Fayoumi GSP and WL-F.
In strain: 25, 7, Black-bone, Black Minorca, Fayoumi GSP, WL-F and WL-N.
In strain: 25, Black Minorca, Fayoumi GSP and WL-F.
In strain: 25, Black-bone, WL-F and WL-N.
In strain: Black Minorca and Fayoumi GSP.
Interferon-induced GTP-binding protein Mx
RNA N6-adenosine-methyltransferase METTL16
Regulator of G-protein signaling 9-binding protein
Loss of quinine- and diphenhydramine-binding, strong decrease in diphenidol-binding, small decrease in chloramphenicol-binding, increase in coumarin-binding, no effect on chlorpheniramine-, nor chloramphenicol-binding.
Loss of quinine-, diphenhydramine- and coumarin-binding, strong decrease in diphenidol-, chloramphenicol- and chloroquine-binding, decrease in chlorpheniramine-binding.
Loss of quinine-, diphenhydramine- and coumarin-binding, strong decrease in diphenidol-, chlorpheniramine-, chloramphenicol- and chloroquine-binding.
Loss of quinine-, diphenhydramine- and coumarin-binding, strong decrease in diphenidol-binding, small decrease in chlorpheniramine- and chloramphenicol-binding, no effect on chloramphenicol-binding.
No effect on quinine-, nor diphenhydramine-binding, small decrease in diphenidol- and chlorpheniramine-binding, strong decrease in chloramphenicol- and chloroquine-binding, increase in coumarin-binding.
Strong decrease in quinine- and diphenhydramine-binding, no effect on diphenidol-, nor chlorpheniramine-binding, small decrease in chloramphenicol- and chloroquine-binding, loss of coumarin-binding.
Strong decrease in quinine-binding, loss of diphenhydramine-binding, small decrease in diphenidol- and chloramphenicol-binding, no effect on chlorpheniramine-, chloramphenicol-, nor coumarin-binding.
Strong increase in quinine-binding, loss of diphenhydramine- and coumarin-binding, small decrease in diphenidol-binding, strong decrease in chlorpheniramine-, chloramphenicol- and chloroquine-binding.
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase
Hydroxysteroid 11-beta-dehydrogenase 1-like protein
Cleavage and polyadenylation specificity factor subunit 6
Dual specificity tyrosine-phosphorylation-regulated kinase 2
Cytochrome b-c1 complex subunit Rieske, mitochondrial
Serine/threonine-protein phosphatase 6 regulatory subunit 3
Sodium-dependent lysophosphatidylcholine symporter 1
Interchain (between beta and alpha chains)
Isoglutamyl cysteine thioester (Cys-Gln)
Cyclic nucleotide-gated channel rod photoreceptor subunit alpha
Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase
Glycosyltransferase-like domain-containing protein 1
G2/M phase-specific E3 ubiquitin-protein ligase
Pterin-4-alpha-carbinolamine dehydratase
Choline/ethanolaminephosphotransferase 1
Spermatid perinuclear RNA-binding protein
43 kDa receptor-associated protein of the synapse
Solute carrier family 2, facilitated glucose transporter member 2
Mediator of RNA polymerase II transcription subunit 22
Actin, aortic smooth muscle, intermediate form
N-acetylglutamate; in Actin, aortic smooth muscle
Acidic leucine-rich nuclear phosphoprotein 32 family member B
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
Ankyrin repeat domain-containing protein 1
Sister chromatid cohesion protein PDS5 homolog B
O-linked (Xyl...) (glycosaminoglycan) serine
Serine/threonine-protein kinase receptor
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3
Dual serine/threonine and tyrosine protein kinase
Pleckstrin homology domain-containing family J member 1
Vascular endothelial growth factor receptor 3
Ubiquitin-associated domain-containing protein 1
Alpha/beta hydrolase domain-containing protein 17B
Stress-70 protein chaperone microsome-associated 60 kDa protein
Katanin p60 ATPase-containing subunit A1
Phosphoethanolamine/phosphocholine phosphatase
Dramatic decrease in antimicrobial activity.
Sodium/potassium-transporting ATPase subunit beta-3
Bactericidal permeability-increasing protein
Cytokine-inducible SH2-containing protein
MAM domain-containing glycosylphosphatidylinositol anchor protein 1
Glyceraldehyde-3-phosphate dehydrogenase
Lethal mitotic defects; when associated with A-22 and A-75. Lethal mitotic defects; when associated with A-11; A-12; A-22; A-54 and A-56. Lethal mitotic defects; when associated with A-11; A-12; A-22 and A-75.
Lethal mitotic defects; when associated with A-7 and A-22. Lethal mitotic defects; when associated with A-7; A-11; A-12 and A-22.
Lethal mitotic defects; when associated with A-7 and A-75. Lethal mitotic defects; when associated with A-7; A-11; A-12; A-54 and A-56. Lethal mitotic defects; when associated with A-7; A-11; A-12 and A-75.
Lethal mitotic defects; when associated with A-7; A-11; A-12; A-22 and A-54.
Lethal mitotic defects; when associated with A-7; A-11; A-12; A-22; and A-56.
Lethal mitotic defects; when associated with A-7; A-11; A-22; A-54 and A-56. Lethal mitotic defects; when associated with A-7; A-11; A-22 and A-75.
Lethal mitotic defects; when associated with A-7; A-12; A-22; A-54 and A-56. Lethal mitotic defects; when associated with A-7; A-12; A-22 and A-75.
Ubiquitin carboxyl-terminal hydrolase BAP1
T-cell surface glycoprotein CD8 alpha chain
Inhibits translocation to the nucleus (Ten-1 ICD form).
Required for interaction with SORBS1 (Ten-1 ICD form)
Rho guanine nucleotide exchange factor 6
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
60 kDa heat shock protein, mitochondrial
Leucine-rich repeat-containing protein 45
Zinc finger CCCH domain-containing protein 14
Cyclic AMP-dependent transcription factor ATF-2
Vacuolar protein sorting-associated protein 29
Serine/threonine-protein phosphatase PP1-beta catalytic subunit
Cell surface glycoprotein CD200 receptor 1-B
Arylamine N-acetyltransferase, liver isozyme
Does not affect significatively biophysicochemical properties.
Hydroxymethylglutaryl-CoA synthase, cytoplasmic
Retinoic acid receptor responder protein 2
Protein-glutamine gamma-glutamyltransferase 2
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Lys-Thr-X-X-X-Trp motif, mediates interaction with the PDZ domain of Dvl family members
Overexpressed in colon carcinoma 1 protein homolog
Abrogates interaction with HDAC2 and impairs transcriptional repression.
Abrogates interaction with RBBP4 and impairs transcriptional repression.
Receptor-type tyrosine-protein phosphatase U
Activity-regulated cytoskeleton-associated protein
Xylosyl- and glucuronyltransferase LARGE1
Interacts with AURKB but fails to fully activate AURKB.
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Asparagine synthetase domain-containing protein 1
Heart- and neural crest derivatives-expressed protein 1
Cysteine sulfinic acid (-SO2H); alternate
Mast/stem cell growth factor receptor Kit
CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial
Rho family-interacting cell polarization regulator 2
Spectrin alpha chain, non-erythrocytic 1
Discoidin, CUB and LCCL domain-containing protein 2
P2R1A-PPP2R2A-interacting phosphatase regulator 1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3
Zinc finger CCCH domain-containing protein 15
Eukaryotic translation initiation factor 3 subunit L
Pro-neuregulin-1, membrane-bound isoform
NAD(P)(+)--arginine ADP-ribosyltransferase
Pterin-4-alpha-carbinolamine dehydratase 2
Probable cation-transporting ATPase 13A4
Nucleolar and spindle-associated protein 1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
Proton acceptor; for glutaminase activity
5-glutamyl glycerylphosphorylethanolamine
Actin, alpha cardiac muscle 1, intermediate form
N-acetylaspartate; in Actin, alpha cardiac muscle 1
Peptide-methionine (R)-S-oxide reductase
Inhibitor of nuclear factor kappa-B kinase subunit alpha
Probable ATP-dependent RNA helicase DDX10
Gly-transPro motif, allows the protein to recognize chirality of D-amino acids
Neuronal acetylcholine receptor subunit alpha-9
dolichyl-phosphate-mannose--protein mannosyltransferase
Bifunctional purine biosynthesis protein ATIC
Proton acceptor; for AICAR formyltransferase activity
Proton donor/acceptor; for FAICAR cyclization activity
Iron-responsive element-binding protein 2
Endothelial differentiation-related factor 1 homolog
7-methylguanosine phosphate-specific 5'-nucleotidase
Major facilitator superfamily domain-containing protein 1
Inhibits partially single-stranded DNA-binding activity but not homodimerization.
Ubiquitin-associated domain-containing protein 2
Chondroitin sulfate proteoglycan 5, 38 kDa form
Chondroitin sulfate proteoglycan 5, 80 kDa form
Fails to bind PIK3R1 in a BCR-signaling dependent manner; when associated with Y-266; Y-423 and Y-448.
Fails to bind PIK3R1 in a BCR-signaling dependent manner; when associated with Y-266; Y-423 and Y-463.
Fails to bind PIK3R1 in a BCR-signaling dependent manner; when associated with Y-266; Y-448 and Y-463.
Fails to bind PIK3R1 in a BCR-signaling dependent manner; when associated with Y-423; Y-448 and Y-463.
Phosphoinositide 3-kinase adapter protein 1
Xylosyl- and glucuronyltransferase LARGE2s
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1
POU domain, class 5, transcription factor 3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1
Dual specificity mitogen-activated protein kinase kinase 2
Elongation of very long chain fatty acids protein 6
Myristoylated alanine-rich C-kinase substrate
Myosin light chain 1, skeletal muscle isoform
Myosin light chain 3, skeletal muscle isoform
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3
Swi5-dependent recombination DNA repair protein 1 homolog
Greatly reduced phosphorylation levels in platelets. Little change in cell spreading. Complete loss of phosphorylation. No change in subcellular location nor on in vitro actin binding. 40% decrease in cell spreading; when associated with F-100.
No change of phosphorylation levels in platelets.
Phosphotyrosine; by SRC-type Tyr-kinases
Some reduction of phosphorylation levels in platelets. Little change in cell spreading. Complete loss of phosphorylation. No change in subcellular location nor on in vitro actin binding. 40% decrease in cell spreading; when associated with F-1134.
Arylamine N-acetyltransferase, pineal gland isozyme NAT-3
Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe
Microtubule-associated protein RP/EB family member 1
Does not reduce the actin-severing activity. Does not affect actin-capping activity.
Reduces the actin-severing activity. Does not affect actin-capping activity.
Does not induce a strong decrease in its electrophoretic retardation.
Induces a strong decrease in its electrophoretic retardation.
Nuclear factor interleukin-3-regulated protein
Trifunctional purine biosynthetic protein adenosine-3
DNA-dependent protein kinase catalytic subunit
Neuronal acetylcholine receptor subunit alpha-10
Acidic leucine-rich nuclear phosphoprotein 32 family member E
Cysteine and histidine-rich domain-containing protein 1
Activating transcription factor 7-interacting protein 1
Low-density lipoprotein receptor-related protein
Protein phosphatase 1 regulatory subunit 12A
Reduces phosphorylation. Reduces phosphorylation on serine and threonine residues by 80%; when associated with A-695.
Reduces phosphorylation. Reduces phosphorylation on serine and threonine residues by 80%; when associated with A-850.
Thiazolidine linkage to a ring-opened DNA abasic site
Lysosome-associated membrane glycoprotein 2
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial
G protein-activated inward rectifier potassium channel 1
Neuroblastoma suppressor of tumorigenicity 1
In isoform 6, isoform 7, isoform 8, isoform 9, isoform 10 and isoform 12.
Cyclic nucleotide-gated channel cone photoreceptor subunit alpha
Limbic system-associated membrane protein
WD repeat domain phosphoinositide-interacting protein 2
Lysosomal cobalamin transport escort protein LMBD1
Katanin p80 WD40 repeat-containing subunit B1
ATP-sensitive inward rectifier potassium channel 12
Myosin regulatory light chain 2, smooth muscle minor isoform
Decrease in E3 ligase activity. Complete loss of myoblast growth suppression activity; when associated with A-260.
Decrease in E3 ligase activity. Loss of myoblast growth suppression activity.
Decrease in E3 ligase activity. Loss of myoblast growth suppression activity; when associated with A-258.
non-specific serine/threonine protein kinase
Alpha/beta hydrolase domain-containing protein 17C
Trafficking protein particle complex subunit 2
Regulation of nuclear pre-mRNA domain-containing protein 1A
Fibroblast growth factor-binding protein 2
Phosphoinositide 3-kinase regulatory subunit 5
Eukaryotic translation initiation factor 2 subunit 1
Reversion-inducing cysteine-rich protein with Kazal motifs
WD repeat domain phosphoinositide-interacting protein 3
Suppressor of tumorigenicity 7 protein homolog
Abolishes binding to OPTN; when associated with E-1088.
Abolishes binding to OPTN; when associated with E-1091.
No effect on binding to OPTN; when associated with A-1088.
No effect on binding to OPTN; when associated with A-1091.
Abrogates interaction with CHAF1B and HIRA.
Phenylalanine--tRNA ligase alpha subunit
5-aminolevulinate synthase, non-specific, mitochondrial
Loss of function in DNA repair; when associated with W-171.
Loss of function in DNA repair; when associated with Y-63.
Mitotic spindle assembly checkpoint protein MAD2B
Mitochondrial tRNA-specific 2-thiouridylase 1
Reduced enzyme activity. Decreased Km values for ADP.
Reduced enzyme activity. Increased Km value for ATP, AMP and ADP. Km value for ThDP decreased to about one fifth of that of the wild-type enzyme.
Ankyrin repeat and MYND domain-containing protein 2
Gamma-aminobutyric acid receptor subunit alpha-2
Strongly reduced tyrosine phosphorylation. Abolishes interaction with GRB2 and INPP5D/SHIP.
Neuronal acetylcholine receptor subunit alpha-4
Decrease in phosphorylation and decrease in regulation of TJP1 binding. Loss of phosphorylation and loss of regulation of TJP1 binding; when associated with F-383.
Decrease in phosphorylation and loss of regulation of TJP1 binding. Loss of phosphorylation and loss of regulation of TJP1 binding; when associated with F-379.
Lower binding to TJP1 and TJP3, decrease in phosphorylation and loss of regulation of TJP1 and TJP3 binding. Lower binding to TJP1 and TJP3, loss of phosphorylation and loss of regulation of TJP1 binding; when associated with D-379.
Lower binding to TJP1, higher binding to TJP3 and decrease in phosphorylation. Lower binding to TJP1 and TJP3, loss of phosphorylation and loss of regulation of TJP1 binding; when associated with D-383.
Ubiquitin carboxyl-terminal hydrolase 10
Oligosaccharyltransferase complex subunit OSTC
Guanine nucleotide-binding protein G(i) subunit alpha-2
Steroidogenic acute regulatory protein, mitochondrial
Vacuolar ATPase assembly integral membrane protein VMA21
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein
Hydroxysteroid dehydrogenase-like protein 1
WLDD motif; essential for 7-methylguanosine-containing mRNA cap binding
Lysosomal amino acid transporter 1 homolog
Disintegrin and metalloproteinase domain-containing protein 9
Transmembrane anterior posterior transformation protein 1 homolog
Phosphoribosyl pyrophosphate synthase-associated protein 2
Nuclear nucleic acid-binding protein C1D
Cytoplasmic dynein 1 light intermediate chain 1
Trafficking protein particle complex subunit 3
Loss of function; when associated with A-452.
Loss of function; when associated with A-578.
Gamma-aminobutyric acid receptor subunit alpha-1
ADP-ribosylation factor-like protein 2-binding protein
Steroid 17-alpha-hydroxylase/17,20 lyase
BAG family molecular chaperone regulator 5
Calcium/calmodulin-dependent protein kinase type II delta chain
CCR4-NOT transcription complex subunit 7
Troponin T, fast skeletal muscle isoforms
Microtubule-associated protein 6 homolog
Loss of binding to the sequence motif K-D-E-L.
Epithelial splicing regulatory protein 2
Circadian locomoter output cycles protein kaput
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)
NEDD8-activating enzyme E1 regulatory subunit
Abolishes homodimerization and cell-cell adhesion; when associated with A-272.
Abolishes homodimerization and cell-cell adhesion; when associated with A-273.
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase
Eukaryotic translation initiation factor 5A-2
Myoblast determination protein 1 homolog
S-adenosylmethionine sensor upstream of mTORC1
Mediator of RNA polymerase II transcription subunit 24
O-linked (Xyl...) (chondroitin sulfate) serine; alternate
O-linked (Xyl...) (heparan sulfate) serine; alternate
Tartrate-resistant acid phosphatase type 5
Granulocyte-macrophage colony-stimulating factor
TATA box-binding protein-associated factor RNA polymerase I subunit B
Extracellular fatty acid-binding protein
Mitochondrial proton/calcium exchanger protein
Tumor necrosis factor alpha-induced protein 8
Eukaryotic translation initiation factor 3 subunit M
Ras-responsive element-binding protein 1
RecQ-mediated genome instability protein 1
Increases channel conductance by almost 100%.
Neuronal acetylcholine receptor subunit beta-2
39S ribosomal protein L15, mitochondrial
Reduces SLC9A1/NHE1 stability and Na(+)/H(+) exchange activities; when associated with A-134.
Reduces SLC9A1/NHE1 stability and Na(+)/H(+) exchange activities; when associated with A-175.
Reduces SLC9A1/NHE1 stability. Does not reduce Na(+)/H(+) SLC9A1/NHE1 exchange activities.
PAN2-PAN3 deadenylation complex catalytic subunit PAN2
Tyrosine-protein phosphatase non-receptor type 1
T-cell-specific surface glycoprotein CD28 homolog
Pleckstrin homology domain-containing family O member 1
Vacuolar protein sorting-associated protein 51 homolog
Loss of function; when associated with A-360.
Loss of function; when associated with A-484.
Actin, cytoplasmic 2, N-terminally processed
N-acetylglutamate; in Actin, cytoplasmic 2, N-terminally processed
N-acetylmethionine; in Actin, cytoplasmic 2; alternate
Calcium-activated potassium channel subunit alpha-1
Pyruvate dehydrogenase E1 component subunit alpha
Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Deamidated asparagine; in forms C1, C2 and C3; partial
Deamidated glutamine; in forms C1 and C2; partial
Deamidated glutamine; in forms C1, C2 and C3; partial
Omega-N-methylarginine; in forms C1, C2 and C3; alternate
Symmetric dimethylarginine; in forms C1, C2 and C3; alternate
KH domain-containing, RNA-binding, signal transduction-associated protein 1
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
G-protein coupled receptor-associated protein LMBRD2
Methylthioribulose-1-phosphate dehydratase
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2
Nuclear envelope integral membrane protein 2
Eukaryotic translation initiation factor 2 subunit 3
In isoform Alpha-KD and isoform Beta-KD.
Dehydrogenase/reductase SDR family member 11
Bromodomain adjacent to zinc finger domain protein 2B
Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog
Calcium release-activated calcium channel protein 1
Suppressor of tumorigenicity 7 protein-like
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform
Mothers against decapentaplegic homolog 3
UbiA prenyltransferase domain-containing protein 1
tRNA (guanine(10)-N2)-methyltransferase homolog
Tyrosine-protein phosphatase non-receptor type 11
Dynamin-like 120 kDa protein, mitochondrial
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial
Transcription initiation factor TFIID subunit 2
H/ACA ribonucleoprotein complex subunit DKC1
Reduced interaction with DNA; when associated with Q-107 and Q-109.
Reduced interaction with DNA; when associated with Q-99 and Q-107.
Reduced interaction with DNA; when associated with Q-99 and Q-109.
Strongly reduced inhibition of cysteine proteases.
Hypoxanthine-guanine phosphoribosyltransferase
ATP-dependent RNA helicase SUPV3L1, mitochondrial
Uracil phosphoribosyltransferase homolog
Nuclear transcription factor Y subunit beta
Insulin-like growth factor 2 mRNA-binding protein 3
Ciliary neurotrophic factor receptor subunit alpha
39S ribosomal protein L37, mitochondrial
39S ribosomal protein L50, mitochondrial
KH domain-containing RNA-binding protein QKI
SET and MYND domain-containing protein 4
116 kDa U5 small nuclear ribonucleoprotein component
Cytosolic Fe-S cluster assembly factor NUBP2
Hyaluronan and proteoglycan link protein 1
ST]-E-Y-X(3)-F motif 1; required for efficient microtubule binding and stabilization
ST]-E-Y-X(3)-F motif 2; required for efficient microtubule binding and stabilization
ST]-E-Y-X(3)-F motif 3; required for efficient microtubule binding and stabilization
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B
Neuronal acetylcholine receptor subunit alpha-2
Almost complete loss of Y RNA binding. About 80-fold decrease in affinity for binding to ACTB transcript, but almost no effect on MYC transcript binding; when associated with 505-E-E-506. Loss of homo- and heterooligomerization with IGF2BP1 and IGF2BP2, almost complete loss of ACTB and MYC transcript binding, almost complete loss of ELAVL1-, DHX9- and HNRNPU-binding and accumulation in the nucleus; when associated with E-213, E-294 and 505-E-E-506.
Decrease in Y RNA binding. About 80-fold decrease in affinity for binding to ACTB transcript, but almost no effect on MYC transcript binding; when associated with 422-E-E-423. Loss of homo- and heterooligomerization with IGF2BP1 and IGF2BP2, almost complete loss of ACTB and MYC transcript binding, almost complete loss of ELAVL1-, DHX9- and HNRNPU-binding and accumulation in the nucleus; when associated with E-213, E-294 and 422-E-E-423.
Decrease in Y RNA binding. Only small decrease in affinity for binding to ACTB and MYC transcripts, some accumulation in the nucleus, and complete loss of formation of higher ordered protein-RNA complexes; when associated with E-213. Loss of homo- and heterooligomerization with IGF2BP1 and IGF2BP2, almost complete loss of ACTB and MYC transcript binding, almost complete loss of ELAVL1-, DHX9- and HNRNPU-binding and accumulation in the nucleus; when associated with E-213, 422-E-E-423 and 505-E-E-506.
Decrease in Y RNA binding. Only small decrease in affinity for binding to ACTB and MYC transcripts, some accumulation in the nucleus, and complete loss of formation of higher ordered protein-RNA complexes; when associated with E-294. Loss of homo- and heterooligomerization with IGF2BP1 and IGF2BP2, almost complete loss of ACTB and MYC transcript binding, almost complete loss of ELAVL1-, DHX9- and HNRNPU-binding and perturbed subcellular location, including accumulation in the nucleus and loss of localization to stress granules; when associated with E-294, 422-E-E-423 and 505-E-E-506.
Impairs the interaction with beta-actin mRNA and its translation repression.
Increases the interaction with ACTB mRNA and its translational repression.
Insulin-like growth factor 2 mRNA-binding protein 1
Polyadenylate-binding protein-interacting protein 2
Replication protein A 70 kDa DNA-binding subunit
Myb/SANT-like DNA-binding domain-containing protein 2
Dihydroorotate dehydrogenase (quinone), mitochondrial
Voltage-gated potassium channel subunit beta-1
Riboflavin-binding protein, yolk major form
Riboflavin-binding protein, yolk minor form
Neuronal PAS domain-containing protein 2
Class E basic helix-loop-helix protein 22
T-cell surface glycoprotein CD3 delta chain
Spindle assembly abnormal protein 6 homolog
tRNA N(3)-methylcytidine methyltransferase METTL2
Tumor necrosis factor alpha-induced protein 8-like protein 1
U3 small nucleolar RNA-associated protein 15 homolog
Microtubule-associated protein RP/EB family member 2
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial
Gamma-aminobutyric acid receptor subunit alpha-6
Histone deacetylase complex subunit SAP130
Cellular retinoic acid-binding protein 1
Schiff-base intermediate with acetaldehyde
Phosphatidylcholine-sterol acyltransferase
Mini-chromosome maintenance complex-binding protein
DNA replication ATP-dependent helicase/nuclease DNA2
Uncharacterized protein KIAA1143 homolog
WAP four-disulfide core domain protein 1
Phosphoenolpyruvate carboxykinase, cytosolic [GTP]
Vitelline membrane outer layer protein 1
Mitochondrial outer membrane protein SLC25A46
Polyribonucleotide 5'-hydroxyl-kinase Clp1
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C
Amiloride-sensitive sodium channel subunit alpha
proton-translocating NAD(P)(+) transhydrogenase
Glycine dehydrogenase (decarboxylating), mitochondrial
Alkaline phosphatase, tissue-nonspecific isozyme
Decreases interaction with SMARCA2 and MED23.
Decreases methylation by CARM1 and increases transactivation activity.
Decreases methylation. Increases transactivation activity inhibition.
Not methylated. Increases interaction with SMARCA2 and MED23.
Phosphothreonine; by RPS6KA1, CDK2 and MAPK
Platelet-derived growth factor subunit B
Potassium voltage-gated channel subfamily D member 2
Proton donor; shared with dimeric partner
Loss of heparin binding; when associated with A-96.
Loss of heparin binding; when associated with A-99.
Receptor-type tyrosine-protein phosphatase S
Abolishes cleavage of C-terminal propeptide.
Abolishes secretion of processed zona pellucida sperm-binding protein 3.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-111.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-152.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-251.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-313.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-332.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-334.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-335.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-340.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-58.
Abolishes secretion of processed zona pellucida sperm-binding protein 3; when associated with A-90.
Impaired homodimerization and abolished secretion of processed zona pellucida sperm-binding protein 3.
Impaired secretion of processed zona pellucida sperm-binding protein 3; when associated with A-229.
Impaired secretion of processed zona pellucida sperm-binding protein 3; when associated with A-295.
Loss of O-glycosylation. No effect on secretion. Reduces binding to the sperm head by about 80%.
Processed zona pellucida sperm-binding protein 3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Protein phosphatase 1 regulatory subunit 21
Trimeric intracellular cation channel type A
Receptor-type tyrosine-protein phosphatase alpha
AT-rich interactive domain-containing protein 5B
Calcitonin gene-related peptide type 1 receptor
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate
Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase
Glycine cleavage system H protein, mitochondrial
Na(+)/H(+) exchange regulatory cofactor NHE-RF1
Myosin regulatory light chain 2, smooth muscle major isoform
Gamma-aminobutyric acid receptor subunit beta-3
Insulin-like growth factor-binding protein 1
Protein kinase C and casein kinase substrate in neurons protein 2
Corticotropin-releasing factor receptor 1
Nuclear receptor subfamily 2 group E member 1
Eukaryotic translation initiation factor 3 subunit E
Leucine-rich repeat-containing protein 59
Tumor necrosis factor receptor superfamily member 6
Cysteine sulfonic acid (-SO3H); alternate
Impairs binding to distorted DNA; when associated with A-12.
Impairs binding to distorted DNA; when associated with A-3.
In Lmbr1-N; associated with preaxial polydactyly.
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Reduces interaction with HOXD12; in association with P-309.
Reduces interaction with HOXD12; in association with P-316.
Neurogenic locus notch homolog protein 1
Platelet-derived growth factor C, latent form
Platelet-derived growth factor C, receptor-binding form
In CHO.MUTCFR mutant; unable to regulate FGF levels and is detected throughout the cell.
Thyroid adenoma-associated protein homolog
Acid sphingomyelinase-like phosphodiesterase
O-linked (Xyl...) (dermatan sulfate) serine
Neuronal acetylcholine receptor subunit alpha-3
Protein-L-histidine N-pros-methyltransferase
Ornithine transcarbamylase, mitochondrial
Transcription initiation factor TFIID subunit 3
26S proteasome non-ATPase regulatory subunit 13
FXYD domain-containing ion transport regulator
Target of Myb1 membrane trafficking protein
Phosphatidylcholine:ceramide cholinephosphotransferase 1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2
Impairs channel activity; when associated with missing 464-L--C-527.
No effect on channel activity; when associated with missing 1-M--S-13. Impairs channel activity; when associated with missing 1-M--S-25.
No effect on channel activity; when associated with missing 464-L--C-527.
Strongly increases speed of desensitation.
Vitamin D3 hydroxylase-associated protein
Target of rapamycin complex 2 subunit MAPKAP1
Mothers against decapentaplegic homolog 5
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
Integrin_alpha2 domain-containing protein
39S ribosomal protein L51, mitochondrial
Ankyrin repeat domain-containing protein 10
CAP-Gly domain-containing linker protein 1
Insulin-like growth factor-binding protein 3
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial
Interphotoreceptor matrix proteoglycan 2
TBC domain-containing protein kinase-like protein
Vascular endothelial growth factor receptor 1
In strain: Black Langshan, Broiler, Dun and Red jungle fowl.
In strain: Broiler, Dun and Red jungle fowl.
Neuronal vesicle trafficking-associated protein 1
cAMP-dependent protein kinase inhibitor alpha
Histone-lysine N-trimethyltransferase SMYD5
EGF domain-specific O-linked N-acetylglucosamine transferase
Ubiquitin-conjugating enzyme E2 variant 1
Peptidyl-prolyl cis-trans isomerase-like 3
RecQ-mediated genome instability protein 2
2-oxoglutarate and iron-dependent oxygenase JMJD4
Polypeptide N-acetylgalactosaminyltransferase
Neuronal acetylcholine receptor subunit alpha-5
p21-activated protein kinase-interacting protein 1-like
Zinc finger and BTB domain-containing protein 14
Protein-L-isoaspartate(D-aspartate) O-methyltransferase
Vacuolar protein sorting-associated protein 53 homolog
Tumor necrosis factor receptor superfamily member 11B
Interleukin-1 receptor accessory protein-like 1
Plasma membrane calcium-transporting ATPase 1
Chromodomain-helicase-DNA-binding protein 7
Serine/threonine-protein kinase 11-interacting protein
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
DNA repair and recombination protein RAD54-like
Cyanocobalamin reductase / alkylcobalamin dealkylase
Loss of Ca(2+) mobilization; when associated with F-194 and F-205. Significant phosphorylation reduction; when associated with F-91; F-103; F-115 and F-194. Loss of phosphorylation; when associated with F-91; F-103; F-115; F-194 and F-249.
Loss of phosphorylation; when associated with F-91; F-103; F-115; F-194 and F-205.
Reduction in Ca(2+) mobilization. Significant reduction of Ca(2+) mobilization; when associated with F-103. Loss of Ca(2+) mobilization; when associated with F-103 and F-205. Significant phosphorylation reduction; when associated with F-91; F-103; F-115 and F-205. Loss of phosphorylation; when associated with F-91; F-103; F-115; F-205 and F-249.
Significant phosphorylation reduction; when associated with F-103; F-115; F-194 and F-205. Loss of phosphorylation; when associated with F-103; F-115; F-194; F-205 and F-249.
Significant phosphorylation reduction; when associated with F-91; F-103; F-194 and F-205. Loss of phosphorylation; when associated with F-91; F-103; F-194; F-205 and F-249.
Significant reduction of Ca(2+) mobilization; when associated with F-194. Loss of Ca(2+) mobilization; when associated with F-194 and F-205. Significant phosphorylation reduction; when associated with F-91; F-115; F-194 and F-205. Loss of phosphorylation; when associated with F-91; F-115; F-194; F-205 and F-249.
Strongly reduced tyrosine phosphorylation. Strongly reduced activation of NFAT.
Abolishes the ability to form a mixed-disulfide with GDPD5; when associated with S-173.
Abolishes the ability to form a mixed-disulfide with GDPD5; when associated with S-52.
Cysteine sulfenic acid (-SOH) intermediate
V-type proton ATPase 116 kDa subunit a 1
DNA repair and recombination protein RAD54B
F-actin-capping protein subunit beta isoforms 1 and 2
Biogenesis of lysosome-related organelles complex 1 subunit 5
Vesicular, overexpressed in cancer, prosurvival protein 1
Gamma-aminobutyric acid receptor subunit beta-4
Translationally-controlled tumor protein homolog
Lutropin-choriogonadotropic hormone receptor
LysM and putative peptidoglycan-binding domain-containing protein 3
Coiled-coil domain-containing protein 93
Ubiquitin-conjugating enzyme E2 variant 2
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
Endosomal/lysosomal proton channel TMEM175
Tudor-interacting repair regulator protein
Nuclear distribution protein nudE homolog 1
Cotranscriptional regulator FAM172A homolog
Lack of phosphorylation; when associated with S-750.
Lack of phosphorylation; when associated with T-753.
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Iroquois-class homeodomain protein IRX-4
No change in heparin-binding activity nor in specific enzymatic activity. Reduced heparin-binding activity and decreased specific enzymatic activity; when associated with N-441.
Reduced heparin-binding ability and some decrease in specific enzymatic activity.
Reduced heparin-binding ability and some reduction in specific enzymatic activity. Almost complete loss of heparin binding and greatly reduced specific enzymatic activity; when associated with N-432 and N-434.
Reduced heparin-binding ability. Almost complete loss of heparin binding and greatly reduced specific enzymatic activity; when associated with N-430 and N-432.
Reduced heparin-binding ability. Almost complete loss of heparin binding and greatly reduced specific enzymatic activity; when associated with N-430 and N-434.
Reduced heparin-binding activity and decreased specific enzymatic activity. No further reduction of heparin-binding nor of specific enzymatic activity; when associated with N-440.
Some loss of heparin-binding ability; when associated with Q-306 and Q-307.
Some loss of heparin-binding ability; when associated with Q-306 and Q-309.
Some loss of heparin-binding ability; when associated with Q-307 and Q-309.
Accumulates in the ER. Loss of palmitoleoylation.
Decreases palmitoleoylation by PORCN. No effect on the activation of the canonical Wnt signaling pathway.
N-acetylthreonine; in GTPase HRas, N-terminally processed
Protein-L-isoaspartate O-methyltransferase
NAD(P)(+)--arginine ADP-ribosyltransferase 1
5-glutamyl coenzyme A thioester intermediate
Potassium voltage-gated channel subfamily A member 10
No significant effect on affinity for ATP and Ca(2+)-calmodulin.
Strongly decreased affinity for ATP and Ca(2+)-calmodulin. Abolishes ATP-mediated increase in channel sensitivity to agonists.
Strongly decreased affinity for ATP and slightly decreased affinity for Ca(2+)-calmodulin.
Transient receptor potential cation channel subfamily V member 4
Proto-oncogene tyrosine-protein kinase receptor Ret
Myeloid differentiation primary response protein MyD88
Trafficking protein particle complex subunit 5
Tumor necrosis factor receptor superfamily member 5
Structural maintenance of chromosomes protein 2
ATP is exchanged at an increased rate; decreased the thermal stability of actin monomers.
Actin, cytoplasmic 1, N-terminally processed
N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed
N-acetylmethionine; in Actin, cytoplasmic 1; alternate
In isoform Brain l-cad and isoform Gizzard l-cad.
Probable ATP-dependent RNA helicase DDX6
Chromatin modification-related protein MEAF6
'Ionic lock' involved in activated form stabilization
Lysophosphatidylcholine acyltransferase 2
Voltage-dependent L-type calcium channel subunit alpha-1D
Sodium/potassium-transporting ATPase subunit alpha-1
Mitochondrial import inner membrane translocase subunit Tim9
Abolishes sequence-specific DNA binding; when associated with A-15 and A-41.
Abolishes sequence-specific DNA binding; when associated with A-15 and A-70.
Abolishes sequence-specific DNA binding; when associated with A-41 and A-70.
Eukaryotic translation initiation factor 3 subunit H
Ectonucleoside triphosphate diphosphohydrolase 8
Intracellular hyaluronan-binding protein 4
Ras-specific guanine nucleotide-releasing factor RalGPS1
Phosphorylated adapter RNA export protein
Mapk-regulated corepressor-interacting protein 1
Complete loss of activity; when associated with Ala-140.
Complete loss of activity; when associated with Ala-142.
Less than 10% activity toward polysaccharide substrates.
Only transfers sulfates to GlcA moieties within the polysaccharide.
Preferentially transfers sulfates to IdoA units.
Troponin C, slow skeletal and cardiac muscles
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form
Endoplasmic reticulum membrane sensor NFE2L1
26S proteasome non-ATPase regulatory subunit 1
Thioredoxin reductase-like selenoprotein T
Does not affect activation by nicked DNA, while it prevents activation by a 3'-overhang substrate.
Protein mono-ADP-ribosyltransferase PARP3
Thioredoxin domain-containing protein 12
Multidrug resistance-associated protein 1
Receptor of activated protein C kinase 1
Zinc finger and BTB domain-containing protein 7A
Signal transducer and activator of transcription 3
Proline-rich nuclear receptor coactivator 2
N6-adenosine-methyltransferase non-catalytic subunit
SKI8 subunit of superkiller complex protein
Gamma-aminobutyric acid receptor subunit gamma-4
Neuronal acetylcholine receptor subunit alpha-6
120 kDa linear IgA disease antigen homolog
Insulin-like growth factor-binding protein 2
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6
Basic helix-loop-helix ARNT-like protein 2
Muscle, skeletal receptor tyrosine protein kinase
Mesoderm induction early response protein 1
Glycyl cysteine thioester (Cys-Gly) (interchain with G-Cter in ubiquitin)
Platelet-derived growth factor receptor alpha
RNA cytosine-C(5)-methyltransferase NSUN2
Double-strand break repair protein MRE11
Abolished proton-coupled folate transport.
Strong proton-coupled folate transport at pH 7.5.
Strongly reduced proton-coupled folate transport.
reversibly protonated residue during proton transport
Ubiquitin carboxyl-terminal hydrolase 48
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
Abolishes phosphorylation following BCR activation; when associated with A-26.
Helical; Signal-anchor for type III membrane protein
Linker for activation of T-cells family member 2
Pleckstrin homology domain-containing family B member 2
Cysteine persulfide intermediate; for sulfurtransferase activity
Glycyl thioester intermediate; for adenylyltransferase activity
Aspartate aminotransferase, mitochondrial
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Abolishes transactivation activity. when associated with A-65.
Abolishes transactivation activity; when associated with A-14.