In MelP5; increase in size of pores (10-12 monomers) that form at lower concentrations of the toxin.
Loss of flexibility in the center of the helix, is twice as effective as melittin as a hemolytic agent but has very poor voltage-gated pore activity in planar bilayers and voltage-dependent ion conductionce is supported only at very high ionic strengths.
Very important decrease of hemolytic activity and capacity of lowering the surface tension of aqueous solutions.
Phosphatidylinositol-glycan biosynthesis class X protein
Dual serine/threonine and tyrosine protein kinase
GPI ethanolamine phosphate transferase 3
Post-GPI attachment to proteins factor 3
Serine/threonine-protein kinase receptor
Translocon-associated protein subunit delta
Mediator of RNA polymerase II transcription subunit 12
Multiple inositol polyphosphate phosphatase 1
Cysteine persulfide intermediate; for sulfurtransferase activity
Glycyl thioester intermediate; for adenylyltransferase activity
non-specific serine/threonine protein kinase
GDP-fucose protein O-fucosyltransferase 1
Immediate early response 3-interacting protein 1
receptor protein serine/threonine kinase
Solute carrier organic anion transporter family member
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein
N-linked (GlcNAc...) (complex) asparagine
Proton acceptor; for processing activity
Schiff-base intermediate with substrate; via pyruvic acid
Brain peptide SQAYDPYSNAAQFQLSSQSRGYPYQHRLVY
Mesencephalic astrocyte-derived neurotrophic factor homolog
Cysteine sulfenic acid (-SOH) intermediate; for peroxidase activity
Lacking the pyrrolidone carboxylic acid modification.
Phosphatidylserine amidated glycine; alternate
Voltage-dependent calcium channel type A subunit alpha-1
Schiff-base intermediate with acetaldehyde
Vesicular, overexpressed in cancer, prosurvival protein 1
Protein-L-isoaspartate O-methyltransferase
Translocon-associated protein subunit beta
5-glutamyl coenzyme A thioester intermediate
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
Mushroom body large-type Kenyon cell-specific protein 1
Translocon-associated protein subunit alpha
GDP-fucose protein O-fucosyltransferase 2
dolichyl-phosphate-mannose--protein mannosyltransferase
heparosan-N-sulfate-glucuronate 5-epimerase
5-glutamyl glycerylphosphorylethanolamine
Sporozoite and liver stage asparagine-rich protein