Removed in mature form; by autocatalysis
GMP synthase [glutamine-hydrolyzing] subunit B
GMP synthase [glutamine-hydrolyzing] subunit A
Phosphoribosylformylglycinamidine synthase subunit PurQ
DNA-directed RNA polymerase subunit Rpo10
Protein-L-isoaspartate O-methyltransferase
O-(3'-phospho-DNA)-tyrosine intermediate
Phenylalanine--tRNA ligase alpha subunit
Pyruvoyl-dependent arginine decarboxylase subunit alpha
Pyruvoyl-dependent arginine decarboxylase subunit beta
Does not affect ring assembly, but abolishes RNA degradation; when associated with E-89.
Does not affect ring assembly, but abolishes RNA degradation; when associated with E-91.
Probable glycine cleavage system H protein
Adenosylcobinamide-GDP ribazoletransferase
tRNA (cytidine(56)-2'-O)-methyltransferase
Putative ABC transporter ATP-binding protein PYRAB01300
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)
Aspartate carbamoyltransferase regulatory chain
Trk system potassium uptake protein TrkA homolog
Schiff-base intermediate with dihydroxyacetone-P
Completely abolishes ATPase activity of the KEOPS complex and completely impairs the tRNA modification activity of the complex.
Cyclic 2,3-diphosphoglycerate synthetase
Digeranylgeranylglyceryl phosphate synthase
Probable dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit
Methylated-DNA--protein-cysteine methyltransferase
Putative [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase
Probable threonylcarbamoyladenosine tRNA methylthiotransferase
3-isopropylmalate dehydratase large subunit 2
tRNA (pseudouridine(54)-N(1))-methyltransferase
DNA double-strand break repair Rad50 ATPase
Geranylgeranylglyceryl phosphate synthase
Glyceraldehyde-3-phosphate dehydrogenase
Nicotinamide-nucleotide adenylyltransferase
3-isopropylmalate dehydratase small subunit 1
Pyridoxal 5'-phosphate synthase subunit PdxS
Schiff-base intermediate with D-ribose 5-phosphate
3-isopropylmalate dehydratase small subunit 2
Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit
Uncharacterized ATP-binding protein PYRAB12000
Glycerol-1-phosphate dehydrogenase [NAD(P)+]
ADP-dependent glucose/glucosamine kinase
Uncharacterized ATP-binding protein PYRAB09480
Tungsten-containing aldehyde ferredoxin oxidoreductase
Uncharacterized HTH-type transcriptional regulator PYRAB00690
tRNA (cytosine(49)-C(5))-methyltransferase
Decreases efficiency of the dimethylation reaction.
Decreases stability of TrmI at extreme temperatures; when associated with S-196.
Decreases stability of TrmI at extreme temperatures; when associated with S-233.
tRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI
Ketoisovalerate oxidoreductase subunit VorD
Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
Ketoisovalerate oxidoreductase subunit VorB
3-methyl-2-oxobutanoate hydroxymethyltransferase
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Pyridoxal 5'-phosphate synthase subunit PdxT
3-hydroxy-3-methylglutaryl-coenzyme A reductase
DNA-directed RNA polymerase subunit Rpo6
DNA-directed RNA polymerase subunit Rpo12
Probable glycine dehydrogenase (decarboxylating) subunit 2
Putative [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase
Nascent polypeptide-associated complex protein
Probable ribosomal RNA small subunit methyltransferase A
Protein-glutamate methylesterase/protein-glutamine glutaminase
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 2
Putative HTH-type transcriptional regulatory protein PYRAB03670
Uncharacterized ATP-binding protein PYRAB06260
Probable glycine dehydrogenase (decarboxylating) subunit 1
Putative 1-aminocyclopropane-1-carboxylate deaminase
Polyribonucleotide 5'-hydroxyl-kinase PYRAB01840
Putative transcriptional regulatory protein PYRAB13000
tRNA (guanine(37)-N1)-methyltransferase Trm5b
Molybdate/tungstate transport system permease protein WtpB
Translation initiation factor 2 subunit alpha
Phosphoribosylformylglycinamidine cyclo-ligase
Digeranylgeranylglycerophospholipid reductase
Lack of tRNA(Phe):m1G methyltransferase activity, but does not affect tRNA(Phe):imG2 methyltransferase activity.
tRNA (guanine(37)-N1)/4-demethylwyosine(37)-methyltransferase Taw22
tRNA (guanine(26)-N(2))-dimethyltransferase
Abolishes iron binding. Reduces the tRNA modification activity of the KEOPS complex by 90%.
Completely impairs the tRNA modification activity of the KEOPS complex. Does not impair ATPase activity of the complex.
Loss of iron, but no change in DNA-binding.
tRNA N6-adenosine threonylcarbamoyltransferase
Uncharacterized HTH-type transcriptional regulator PYRAB04820
Molybdopterin synthase catalytic subunit
Proton acceptor; for processing activity
S-adenosylmethionine decarboxylase alpha chain
S-adenosylmethionine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Translation initiation factor 2 subunit beta
Does not affect ring assembly, but decreases RNA degradation.
Involved in ionization of N3 of dUMP, leading to its activation
tRNA (uracil(54)-C(5))-methyltransferase
Indolepyruvate oxidoreductase subunit IorA
O-(5'-phospho-DNA)-tyrosine intermediate
Uncharacterized DapA-like lyase PYRAB12600
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Ribosomal RNA small subunit methyltransferase Nep1
Probable Brix domain-containing ribosomal biogenesis protein
tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase 1
Putative 6-carboxy-5,6,7,8-tetrahydropterin synthase
Pyruvate/ketoisovalerate oxidoreductases common subunit gamma
DNA polymerase II large subunit, 1st part
DNA polymerase II large subunit, 2nd part
DNA-directed RNA polymerase subunit Rpo11
Indolepyruvate oxidoreductase subunit IorB
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Putative methylthioribose-1-phosphate isomerase
Cysteine sulfenic acid (-SOH) intermediate
23S rRNA (uracil(747)-C(5))-methyltransferase
DNA-directed RNA polymerase subunit Rpo1C
Signal recognition particle 54 kDa protein
Putative translation initiation factor eIF-2B subunit 2-like
Molybdate/tungstate-binding protein WtpA
Glutamyl-tRNA(Gln) amidotransferase subunit D
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Molybdate/tungstate import ATP-binding protein WtpC
Probable molybdenum cofactor guanylyltransferase
V-type ATP synthase alpha chain, 1st part
V-type ATP synthase alpha chain, 2nd part
Ribosome maturation protein SDO1 homolog
3-isopropylmalate dehydratase large subunit 1
N-(5'-phosphoribosyl)anthranilate isomerase
Gly-Pro-Asn (GPN)-loop; involved in dimer interface
Putative [LysW]-aminoadipate/[LysW]-glutamate kinase
Uncharacterized HTH-type transcriptional regulator PYRAB00550
Formate-dependent phosphoribosylglycinamide formyltransferase
Putative ABC transporter ATP-binding protein PYRAB03730
DNA repair and recombination protein RadA
Probable cobalamin biosynthesis protein CobD
Probable chemoreceptor glutamine deamidase CheD
tRNA(Met) cytidine acetyltransferase TmcA
Phosphate import ATP-binding protein PstB
UPF0173 metal-dependent hydrolase PYRAB05000
Uncharacterized HTH-type transcriptional regulator PYRAB16920
Phosphoribosylformylglycinamidine synthase subunit PurL
Putative [LysW]-lysine/[LysW]-ornithine hydrolase
DNA-directed RNA polymerase subunit Rpo5
Signal recognition particle 19 kDa protein
Uncharacterized HTH-type transcriptional regulator PYRAB09690
Translation initiation factor 2 subunit gamma
Isolated domain does not deacylate mischarged L-seryl-tRNA(Thr).
Isolated domain has decreased to no deacylation of mischarged L-seryl-tRNA(Thr). Deacylates correctly charged glycyl-tRNA(Gly).
Isolated domain has nearly wild-type deacylation of mischarged L-seryl-tRNA(Thr), no longer binds L-Ser or L-Cys. No activity on threonyl-tRNA(Thr). Same results; when associated with A-134.
Isolated domain has nearly wild-type deacylation of mischarged L-seryl-tRNA(Thr). Later shown not to deacylate L-seryl-tRNA(Thr), no activity on L-threonyl-tRNA(Thr).
Isolated domain has nearly wild-type deacylation of mischarged L-seryl-tRNA(Thr). No activity on L-threonyl-tRNA(Thr). Same results; when associated with A-120.