Methyl-coenzyme M reductase I operon protein C
Tetrahydromethanopterin S-methyltransferase subunit E
Probable N5-carboxyaminoimidazole ribonucleotide mutase
Putative metallophosphoesterase MTH_1774
Tetrahydromethanopterin S-methyltransferase subunit H
Nitrogenase molybdenum-iron protein beta chain
Glutamyl-tRNA(Gln) amidotransferase subunit D
5,10-methenyltetrahydromethanopterin hydrogenase
Glutamate-1-semialdehyde 2,1-aminomutase
DNA double-strand break repair Rad50 ATPase
Phosphate-specific transport system accessory protein PhoU homolog 1
F420-dependent methylenetetrahydromethanopterin dehydrogenase
Energy-coupling factor transporter ATP-binding protein EcfA
Tetrahydromethanopterin S-methyltransferase subunit D
Ni-sirohydrochlorin a,c-diamide reductive cyclase complex, component CfbD
Ribosomal RNA large subunit methyltransferase E
DNA-directed RNA polymerase subunit Rpo2C
Glycerol-3-phosphate dehydrogenase [NAD(P)+]
H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit A
DNA double-strand break repair protein Mre11
Methyl-coenzyme M reductase II subunit beta
DNA-directed RNA polymerase subunit Rpo10
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase
Nitrogenase molybdenum-iron protein alpha chain
2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase
Ketoisovalerate oxidoreductase subunit VorC
DNA-directed RNA polymerase subunit Rpo11
Formylmethanofuran--tetrahydromethanopterin formyltransferase
UPF0425 pyridoxal phosphate-dependent protein MTH_1914
Probable ribosomal RNA small subunit methyltransferase A
F420-non-reducing hydrogenase iron-sulfur subunit D
Nascent polypeptide-associated complex protein
Probable nicotinate-nucleotide pyrophosphorylase [carboxylating]
N-(5'-phosphoribosyl)anthranilate isomerase
4-hydroxy-tetrahydrodipicolinate reductase
Probable cobalt-factor III C(17)-methyltransferase
Methenyltetrahydromethanopterin cyclohydrolase
Putative HTH-type transcriptional regulatory protein MTH_967
Phosphoribosylformylglycinamidine synthase subunit PurQ
Peptide methionine sulfoxide reductase MsrB
Probable L-tyrosine/L-aspartate decarboxylase
Sugar fermentation stimulation protein homolog
Loss of DNA uridine endonuclease and 3'-5' exonuclease activities. Has weak AP endonuclease activity.
Succinate--CoA ligase [ADP-forming] subunit beta
Digeranylgeranylglyceryl phosphate synthase
GMP synthase [glutamine-hydrolyzing] subunit B
Phenylalanine--tRNA ligase alpha subunit
Decreased DNA-binding to replication forks, decreased ssDNA-stimulated ATPase. Decreased helicase activity. No binding to RPA.
No change in DNA-binding to replication forks. Basal ATPase 4-5 fold higher than wild-type, ssDNA stimulation is less effective than wild-type. Almost no helicase activity. Binds RPA.
No change in DNA-binding to replication forks. Decreased ssDNA stimulation of ATPase. Almost no helicase activity. Binds RPA.
No helicase activity, 6% ATPase activity. Binds fork DNA as well as wild-type; also supershifts with RFA.
Reduced duplex DNA-binding and unwinding activity, without affecting single-stranded DNA-binding.
Strongly reduced ATPase and helicase activity.
Acetyl-CoA decarbonylase/synthase complex subunit gamma
Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B
O-phospho-L-seryl-tRNA:Cys-tRNA synthase
Ketoisovalerate oxidoreductase subunit VorB
Uncharacterized ATP-dependent helicase MTH_1802
Probable translation initiation factor IF-2
Molybdenum-containing formylmethanofuran dehydrogenase 1 subunit C
Methyl-coenzyme M reductase I operon protein D
Probable 3-isopropylmalate dehydratase large subunit
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase
3-hydroxy-3-methylglutaryl-coenzyme A reductase
Methyl-coenzyme M reductase II operon protein D
N-acetyl-gamma-glutamyl-phosphate reductase
Long-type peptidyl-prolyl cis-trans isomerase
Signal recognition particle 19 kDa protein
(5-formylfuran-3-yl)methyl phosphate synthase
Uncharacterized HTH-type transcriptional regulator MTH_1328
Archaetidylserine decarboxylase alpha chain
Archaetidylserine decarboxylase beta chain
Schiff-base intermediate with substrate; via pyruvic acid
Carbamoyl-phosphate synthase small chain
Pyridoxal 5'-phosphate synthase subunit PdxT
2,3-bisphosphoglycerate-independent phosphoglycerate mutase 1
Sulfopyruvate decarboxylase subunit beta
Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE
Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C
Cobalt-precorrin-5B C(1)-methyltransferase
At high calcium concentration, mean open time is short and mean closed time is long compared with wild-type.
Elimination of the 26 kDa product and reduced levels of channel expression.
Hypoxanthine/guanine phosphoribosyltransferase
Glycerol-1-phosphate dehydrogenase [NAD(P)+]
Formylmethanofuran--tetrahydromethanopterin formyltransferase-like protein
Short chain isoprenyl diphosphate synthase
Ribosome maturation protein SDO1 homolog
Decrease in dsDNA binding and strong decrease in ssDNA binding.
Tetrahydromethanopterin S-methyltransferase subunit B
Sulfopyruvate decarboxylase subunit alpha
UPF0173 metal-dependent hydrolase MTH_1902
O-(3'-phospho-DNA)-tyrosine intermediate
DNA repair and recombination protein RadB
Proton acceptor; for FBP phosphatase activity
Proton donor/acceptor; for FBP aldolase activity
Schiff-base intermediate with DHAP; for FBP aldolase activity
Imidazole glycerol phosphate synthase subunit HisF
Tritrans,polycis-undecaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific)
Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)
ADP-ribosylarginine; by dinitrogenase reductase ADP-ribosyltransferase
Tetrahydromethanopterin S-methyltransferase subunit A 1
Removed in mature form; by autocatalysis
Translation initiation factor 2 subunit gamma
tRNA (guanine(26)-N(2))-dimethyltransferase
H(2):CoB-CoM heterodisulfide,ferredoxin reductase subunit B
Methyl-coenzyme M reductase II subunit alpha
5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase
Phosphoribosylformylglycinamidine synthase subunit PurS
DNA repair and recombination protein RadA
Methyl-coenzyme M reductase I subunit beta
Phosphoribosylformylglycinamidine synthase subunit PurL
Putative branched-chain-amino-acid aminotransferase
3-isopropylmalate dehydratase small subunit
Probable S-adenosyl-L-methionine-binding protein MTH_1797
DNA-directed RNA polymerase subunit Rpo5
Putative glutamine amidotransferase MTH_191
Signal recognition particle 54 kDa protein
Probable Brix domain-containing ribosomal biogenesis protein
Indolepyruvate oxidoreductase subunit IorB
4-hydroxy-tetrahydrodipicolinate synthase
5,10-methylenetetrahydromethanopterin reductase
Methyl-coenzyme M reductase subunit alpha
Probable bifunctional tRNA threonylcarbamoyladenosine biosynthesis protein
Trk system potassium uptake protein TrkA homolog
Probable S-methyl-5'-thioinosine phosphorylase
Tetrahydromethanopterin S-methyltransferase subunit F
Imidazole glycerol phosphate synthase subunit HisH
Tetrahydromethanopterin S-methyltransferase subunit C
Indolepyruvate oxidoreductase subunit IorA
Probable cobalamin biosynthesis protein CobD
Methyl-coenzyme M reductase I subunit gamma
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Digeranylgeranylglycerophospholipid reductase 2
Phosphoribosylformylglycinamidine cyclo-ligase
3-phosphoshikimate 1-carboxyvinyltransferase
Nicotinamide-nucleotide adenylyltransferase
Putative biopolymer transport protein ExbB homolog
Acetyl-CoA decarbonylase/synthase complex subunit beta
DNA-directed RNA polymerase subunit Rpo3
Adenosylcobinamide-GDP ribazoletransferase
Translation initiation factor 2 subunit beta
Forms homodimers. Shows almost wild-type activity.
Geranylgeranylglyceryl phosphate synthase
Tetrahydromethanopterin S-methyltransferase subunit G
Glyceraldehyde-3-phosphate dehydrogenase
Phosphoribosylaminoimidazole-succinocarboxamide synthase
Putative phospho-N-acetylmuramoyl-pentapeptide-transferase
Glutamyl-tRNA(Gln) amidotransferase subunit E
DNA-directed RNA polymerase subunit Rpo1N
tRNA (guanine(10)-N2)-dimethyltransferase