Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.
Azole drugs trap cytochrome P450 EryK in alternative conformational states.
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea.
Identification of a Saccharopolyspora erythraea gene required for the final hydroxylation step in erythromycin biosynthesis.
Investigating the structural plasticity of a cytochrome P450: three-dimensional structures of P450 EryK and binding to its physiological substrate.
Nucleotide sequence of the ermE distal flank of the erythromycin biosynthesis cluster in Saccharopolyspora erythraea.
Overproduction and characterization of the erythromycin C-12 hydroxylase, EryK.
An erythromycin derivative produced by targeted gene disruption in Saccharopolyspora erythraea.
Cloning and sequence analysis of genes involved in erythromycin biosynthesis in Saccharopolyspora erythraea: sequence similarities between EryG and a family of S-adenosylmethionine-dependent methyltransferases.
Mutation and cloning of eryG, the structural gene for erythromycin O-methyltransferase from Saccharopolyspora erythraea, and expression of eryG in Escherichia coli.
Sequencing and mutagenesis of genes from the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea that are involved in L-mycarose and D-desosamine production.
Current status and future opportunities for serial crystallography at MAX IV Laboratory.
A repeated decapeptide motif in the C-terminal domain of the ribosomal RNA methyltransferase from the erythromycin producer Saccharopolyspora erythraea.
Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus.
N-methyl transferase of Streptomyces erythraeus that confers resistance to the macrolide-lincosamide-streptogramin B antibiotics: amino acid sequence and its homology to cognate R-factor enzymes from pathogenic bacilli and cocci.
Molecular characterization of a gene from Saccharopolyspora erythraea (Streptomyces erythraeus) which is involved in erythromycin biosynthesis.
Analysis of an 8.1-kb DNA fragment contiguous with the erythromycin gene cluster of Saccharopolyspora erythraea in the eryCI-flanking region.
Amino acid sequence of chitinase from Streptomyces erythraeus.
The bacterial iron sensor IdeR recognizes its DNA targets by indirect readout.
Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase.
Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol.
In vitro reconstitution of EryCIII activity for the preparation of unnatural macrolides.
Reconstitution and characterization of a new desosaminyl transferase, EryCIII, from the erythromycin biosynthetic pathway.
Structure of the glycosyltransferase EryCIII in complex with its activating P450 homologue EryCII.
Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea.
Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase.
Conformational remodeling enhances activity of lanthipeptide zinc-metallopeptidases.
Crystal structures of ligand complexes of P450eryF exhibiting homotropic cooperativity.
Crystal structures of the ferrous dioxygen complex of wild-type cytochrome P450eryF and its mutants, A245S and A245T: investigation of the proton transfer system in P450eryF.
Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF.
Structure of cytochrome P450eryF involved in erythromycin biosynthesis.
Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.
A small, discrete acyl carrier protein is involved in de novo fatty acid biosynthesis in Streptomyces erythraeus.
Cloning, characterization, and high-level expression in Escherichia coli of the Saccharopolyspora erythraea gene encoding an acyl carrier protein potentially involved in fatty acid biosynthesis.