Integration of the genetic map and genome assembly of fugu facilitates insights into distinct features of genome evolution in teleosts and mammals.
Ligand-dependent transcriptional activities of four torafugu pufferfish Takifugu rubripes peroxisome proliferator-activated receptors.
Am. J. Physiol. Regul. Integr. Comp. Physiol.
Identification and proximal tubular localization of the Mg?? transporter, Slc41a1, in a seawater fish.
Identification and proximal tubular localization of the Mg^2⁺ transporter, Slc41a1, in a seawater fish.
Comp. Biochem. Physiol. B, Biochem. Mol. Biol.
Expression and distribution of fugu TIMP-2s (fgTIMP-2a and fgTIMP-2b) mRNAs in tissues and embryos.
Functional and comparative analysis of globin loci in pufferfish and humans.
AP1 genes in Fugu indicate a divergent transcriptional control to that of mammals.
Genomic organization and expression of CD8alpha and CD8beta genes in fugu Takifugu rubripes.
The melanocortin system in Fugu: determination of POMC/AGRP/MCR gene repertoire and synteny, as well as pharmacology and anatomical distribution of the MCRs.
Convergent loss of an anciently duplicated, functionally divergent RH2 opsin gene in the fugu and Tetraodon pufferfish lineages.
Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters.
The mitochondrial genome of spotted green pufferfish Tetraodon nigroviridis (Teleostei: Tetraodontiformes) and divergence time estimation among model organisms in fishes.
The mitochondrial genome of the pufferfish, Fugu rubripes, and ordinal teleostean relationships.
Comparative analyses of multi-species sequences from targeted genomic regions.
Three receptor genes for plasminogen related growth factors in the genome of the puffer fish Fugu rubripes.
FRG1, a gene in the FSH muscular dystrophy region on human chromosome 4q35, is highly conserved in vertebrates and invertebrates.
Molecular cloning of 5-hydroxytryptamine (5-HT) type 1 receptor genes from the Japanese puffer fish, Fugu rubripes.
Analysis of 148 kb of genomic DNA around the wnt1 locus of Fugu rubripes.
Sequencing and comparative analysis of fugu protocadherin clusters reveal diversity of protocadherin genes among teleosts.
Characterization of the neuroligin gene family expression and evolution in zebrafish.
A novel rod-like opsin isolated from the extra-retinal photoreceptors of teleost fish.
Origin of INSL3-mediated testicular descent in therian mammals.
Molecular cloning and biochemical characterization of sialidases from zebrafish (Danio rerio).
FAM20: an evolutionarily conserved family of secreted proteins expressed in hematopoietic cells.
Evolution of the vertebrate twist family and synfunctionalization: a mechanism for differential gene loss through merging of expression domains.
Molecular evolution of matrix metalloproteinase 20.
Characterization of two paralogous muscleblind-like genes from the tiger pufferfish (Takifugu rubripes).
Molecular cloning, functional characterization and phylogenetic analysis of TRAIL in Japanese pufferfish Takifugu rubripes.
PACAP, VIP and their receptors in the metazoa: insights about the origin and evolution of the ligand-receptor pair.
The evolution of SMC proteins: phylogenetic analysis and structural implications.
Identification of a novel adrenomedullin gene family in teleost fish.
Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes.
Description of a fugu CXC chemokine and two CXC receptor genes, and characterization of the effects of different stimulators on their expression.
Genes coding for intermediate filament proteins: common features and unexpected differences in the genomes of humans and the teleost fish Fugu rubripes.
Novel vertebrate genes and putative regulatory elements identified at kidney disease and NR2E1/fierce loci.
Characterization and tissue distribution of multiple agouti-family genes in pufferfish, Takifugu rubripes.
Genomic identification and biochemical characterization of a second spermidine/spermine N1-acetyltransferase.
Interaction of fish aryl hydrocarbon receptor paralogs (AHR1 and AHR2) with the retinoblastoma protein.
Characterisation of a gene cluster in Fugu rubripes containing the complement component C4 gene.
Fugu rubripes and human survival motor neuron genes: structural and functional similarities in comparative genome studies.
Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions.
Phenogenetic drift in evolution: the changing genetic basis of vertebrate teeth.
Characterization of three genes, AKAP84, BAW and WSB1, located 3' to the neurofibromatosis type 1 locus in Fugu rubripes.
Genomic, evolutionary, and expression analyses of cee, an ancient gene involved in normal growth and development.
Teleost B7 expressed on monocytes regulates T cell responses.
Identification and lateral membrane localization of cyclin M3, likely to be involved in renal Mg2+ handling in seawater fish.
Genomic structure and comparative analysis of nine Fugu genes: conservation of synteny with human chromosome Xp22.2-p22.1.
Isolation, characterization and evolution of nine pufferfish (Fugu rubripes) actin genes.
Intron loss in the SART1 genes of Fugu rubripes and Tetraodon nigroviridis.
The mouse homolog of FRG1, a candidate gene for FSHD, maps proximal to the myodystrophy mutation on chromosome 8.
The comparative genomic structure and sequence of the surfeit gene homologs in the puffer fish Fugu rubripes and their association with CpG-rich islands.
Origin and diversity of the SOX transcription factor gene family: genome-wide analysis in Fugu rubripes.
Human homologs of the putative G protein-coupled membrane progestin receptors (mPRalpha, beta, and gamma) localize to the endoplasmic reticulum and are not activated by progesterone.
Molecular cloning and functional characterization of a high-affinity zinc importer (DrZIP1) from zebrafish (Danio rerio).
Genomics, evolution, and expression of TBPL2, a member of the TBP family.
TRF3, a TATA-box-binding protein-related factor, is vertebrate-specific and widely expressed.
Characterisation and expression analysis of interleukin 2 (IL-2) and IL-21 homologues in the Japanese pufferfish, Fugu rubripes, following their discovery by synteny.
Analysis of the reticulon gene family demonstrates the absence of the neurite growth inhibitor Nogo-A in fish.
Ammonia secretion from fish gill depends on a set of Rh glycoproteins.
Evolutionary conservation and diversification of Rh family genes and proteins.
A novel type of P450c17 lacking the lyase activity is responsible for C21-steroid biosynthesis in the fish ovary and head kidney.
Genomic characterization and expression analysis of the first nonmammalian renin genes from zebrafish and pufferfish.
Identification of pepsinogen gene in the genome of stomachless fish, Takifugu rubripes.
Organization of the Fugu rubripes Hox clusters: evidence for continuing evolution of vertebrate Hox complexes.
Analysis of the dopamine receptor family in the compact genome of the puffer fish Fugu rubripes.
Characterization and expression analysis of CD3varepsilon and CD3gamma/delta in fugu, Takifugu rubripes.
Cloning, expression and subcellular localization of HN1 and HN1L genes, as well as characterization of their orthologs, defining an evolutionarily conserved gene family.
Multiple gene organization of pufferfish Fugu rubripes tropomyosin isoforms and tissue distribution of their transcripts.
An enigmatic fourth runt domain gene in the fugu genome: ancestral gene loss versus accelerated evolution.
cDNA cloning of Runx family genes from the pufferfish (Fugu rubripes).
Genomic characterization and tissue distribution of leptin receptor and leptin receptor overlapping transcript genes in the pufferfish, Takifugu rubripes.
Characterization of snRNA and snRNA-type genes in the pufferfish Fugu rubripes.
O2-filled swimbladder employs monocarboxylate transporters for the generation of O2 by lactate-induced root effect hemoglobin.
Evolution of teleostean hatching enzyme genes and their paralogous genes.
Teleost multiple tissue (tmt) opsin: a candidate photopigment regulating the peripheral clocks of zebrafish?
Conserved regulation of the lymphocyte-specific expression of lck in the Fugu and mammals.
The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach.
Phylogenetic and functional analysis of histidine residues essential for pH-dependent multimerization of von Willebrand factor.
Characterization of the pufferfish Otx2 cis-regulators reveals evolutionarily conserved genetic mechanisms for vertebrate head specification.
Identification of an achaete-scute homolog, Fash1, from Fugu rubripes.
Analysis of the exon-intron structures of fish, amphibian, bird and mammalian hatching enzyme genes, with special reference to the intron loss evolution of hatching enzyme genes in Teleostei.
Rapid Diversification of FoxP2 in Teleosts through Gene Duplication in the Teleost-Specific Whole Genome Duplication Event.
Two interleukin (IL)-15 homologues in fish from two distinct origins.
Costimulatory receptors in a teleost fish: typical CD28, elusive CTLA4.
Costimulatory receptors in jawed vertebrates: conserved CD28, odd CTLA4 and multiple BTLAs.
Four functionally distinct C-type natriuretic peptides found in fish reveal evolutionary history of the natriuretic peptide system.
Functional characterisation and genomic analysis of an epithelial calcium channel (ECaC) from pufferfish, Fugu rubripes.
Identification and analysis of two snail genes in the pufferfish (Fugu rubripes) and mapping of human SNA to 20q.
Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.
Comparative analysis of the RED1 and RED2 A-to-I RNA editing genes from mammals, pufferfish and zebrafish.
CRTAC1 homolog proteins are conserved from cyanobacteria to man and secreted by the teleost fish pituitary gland.
Fugu (Takifugu rubripes) Sexual Differentiation: CYP19 Regulation and Aromatase Inhibitor Induced Testicular Development.
Prolactin and prolactin receptor expressions in a marine teleost, pufferfish Takifugu rubripes.
Pillar cell and erythrocyte localization of fugu ET(A) receptor and its implication.
Characterization of the platelet-derived growth factor receptor alpha and c-kit genes in the pufferfish Fugu rubripes.
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus).
Diversification of non-visual photopigment parapinopsin in spectral sensitivity for diverse pineal functions.
Fish calcitonin receptor has novel features.
Multiple noggins in vertebrate genome: cloning and expression of noggin2 and noggin4 in Xenopus laevis.
Characterization and expression analysis of an interleukin-7 homologue in the Japanese pufferfish, Takifugu rubripes.
Molecular cloning and sequencing of Japanese pufferfish (Takifugu rubripes) NADPH oxidase cDNAs.
Teleost IL-6 promotes antibody production through STAT3 signaling via IL-6R and gp130.
The evolution of vertebrate Toll-like receptors.
Characterization of the transcription factor MTF-1 from the Japanese pufferfish (Fugu rubripes) reveals evolutionary conservation of heavy metal stress response.
Identification of three prominin homologs and characterization of their messenger RNA expression in Xenopus laevis tissues.
Fugu and human sequence comparison identifies novel human genes and conserved non-coding sequences.
Transgenic rats reveal functional conservation of regulatory controls between the Fugu isotocin and rat oxytocin genes.
Evolution of sialic acid-binding proteins: molecular cloning and expression of fish siglec-4.
Cloning and sequencing of the chaperonin-encoding Cctd gene from Fugu rubripes rubripes.
Duplicated receptors for VIP and PACAP (VPAC1R and PAC1R) in a teleost fish, Fugu rubripes.
Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1.
Identification and characterization of Fugu orthologues of mammalian interleukin-12 subunits.
Structure and evolution of the Teleost extraretinal rod-like opsin (errlo) and ocular rod opsin (rho) genes: Is teleost rho a retrogene?
Isolation and characterization of the retinoic acid receptor-alpha gene in the Japanese pufferfish, F. rubripes.
An evolutionary basis for scrapie disease: identification of a fish prion mRNA.
Detecting conserved regulatory elements with the model genome of the Japanese puffer fish, Fugu rubripes.
Genetic basis for the evolution of vertebrate mineralized tissue.
Molecular cloning and expression of gelatinases (MMP-2 and MMP-9) in the pufferfish Takifugu rubripes.
Characterization of the Fugu rubripes NLK and FN5 genes flanking the NF1 (Neurofibromatosis type 1) gene in the 5' direction and mapping of the human counterparts.
B-lymphocyte-induced maturation protein-1 (Blimp-1) gene of torafugu (Takifugu rubripes).
cDNA sequence and tissue expression of Fugu rubripes prion protein-like: a candidate for the teleost orthologue of tetrapod PrPs.
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2.
Structural basis of antagonizing the vitamin K catalytic cycle for anticoagulation.
Characterization and expression analysis of Th-POK from the Japanese pufferfish, Takifugu rubripes.
Differential regulation of multiple alternatively spliced transcripts of MyoD.
Cloning, expression, and characterization of fugu CD4, the first ectothermic animal CD4.
Genomic organization and expression of the doublesex-related gene cluster in vertebrates and detection of putative regulatory regions for DMRT1.
Two families of candidate taste receptors in fishes.
Characterisation, expression and promoter analysis of an interleukin 10 homologue in the puffer fish, Fugu rubripes.
Characterization of STIP, a multi-domain nuclear protein, highly conserved in metazoans, and essential for embryogenesis in Caenorhabditis elegans.
Identification of cDNA coding for a homologue to mammalian leptin from pufferfish, Takifugu rubripes.
Genomic characterization of the RUNX2 gene of Fugu rubripes.
Structural characterisation of a cyprinid (Cyprinus carpio L.) CRH, CRH-BP and CRH-R1, and the role of these proteins in the acute stress response.
Putative pheromone receptors related to the Ca2+-sensing receptor in Fugu.
Identification of three isoforms for mitochondrial adenine nucleotide translocator in the pufferfish Takifugu rubripes.
A functional role for some Fugu introns larger than the typical short ones: the example of the gene coding for ribosomal protein S7 and snoRNA U17.
Functional expression of a low-affinity zinc uptake transporter (FrZIP2) from pufferfish (Takifugu rubripes) in MDCK cells.
Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs.
Comparative genomics of the SOX9 region in human and Fugu rubripes: conservation of short regulatory sequence elements within large intergenic regions.
Identification of a stanniocalcin paralog, stanniocalcin-2, in fish and the paracrine actions of stanniocalcin-2 in the mammalian ovary.
Neurokinin Bs and neurokinin B receptors in zebrafish-potential role in controlling fish reproduction.
Characterization of the pufferfish Takifugu rubripes apolipoprotein multigene family.
Two alternatively spliced GPR39 transcripts in seabream: molecular cloning, genomic organization, and regulation of gene expression by metabolic signals.
Molecular cloning and characterization of secretory carbonic anhydrase VI in pufferfish (Takifugu rubripes).
Multiple processing of Ig-Hepta/GPR116, a G protein-coupled receptor with immunoglobulin (Ig)-like repeats, and generation of EGF2-like fragment.
Molecular cloning and expression of pyruvate kinase from globefish (Fugu rubripes) skeletal muscle.
Comparative analysis of the genomic organization of Pax9 and its conserved physical association with Nkx2-9 in the human, mouse, and pufferfish genomes.
Comparative analysis of vertebrate Shh genes identifies novel conserved non-coding sequence.
TMC and EVER genes belong to a larger novel family, the TMC gene family encoding transmembrane proteins.
Ras-dva, a member of novel family of small GTPases, is required for the anterior ectoderm patterning in the Xenopus laevis embryo.
Molecular cloning of two cannabinoid type 1-like receptor genes from the puffer fish Fugu rubripes.
Conservation of structure and functional divergence of duplicated Wnt8s in pufferfish.
Gonadotropin hormone and receptor sequences from model teleost species.
Ca2+ channel-independent requirement for MAGUK family CACNB4 genes in initiation of zebrafish epiboly.
Genomic organization, expression, and phylogenetic analysis of Ca2+ channel beta4 genes in 13 vertebrate species.
The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafish.
The 350-fold compacted Fugu parkin gene is structurally and functionally similar to human Parkin.
Characterisation and expression analysis of an interleukin 6 homologue in the Japanese pufferfish, Fugu rubripes.
Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries.
Structure and evolution of vertebrate aldehyde oxidases: from gene duplication to gene suppression.
Multiple and highly divergent IL-11 genes in teleost fish.
Genomic sequence analysis of Fugu rubripes CFTR and flanking genes in a 60 kb region conserving synteny with 800 kb of human chromosome 7.
Identification and characterization of evolutionarily conserved pufferfish, zebrafish, and frog orthologs of GASZ.
Disparate evolution of prion protein domains and the distinct origin of Doppel- and prion-related loci revealed by fish-to-mammal comparisons.
A novel tumor necrosis factor (TNF) gene present in tandem with theTNF-alpha gene on the same chromosome in teleosts.
Lectins homologous to those of monocotyledonous plants in the skin mucus and intestine of pufferfish, Fugu rubripes.
Characterization of the recombinase activating gene-1 and 2 locus in the Japanese pufferfish, Fugu rubripes.
Comparative genomics approach to the expression of figalpha, one of the earliest marker genes of oocyte differentiation in medaka (Oryzias latipes).
Identification and expression analysis of an IL-18 homologue and its alternatively spliced form in rainbow trout (Oncorhynchus mykiss).
The structure, expression and function prediction of DAZAP2, a down-regulated gene in multiple myeloma.
Expression of fugu TIMP-3 and -4 genes in adult tissues and embryos.
Isolation and genomic characterization of the TUPLE1/HIRA gene of the pufferfish Fugu rubripes.
Cloning and sequencing of complement component C9 and its linkage to DOC-2 in the pufferfish Fugu rubripes.
Lineage-specific expansions and contractions of the bitter taste receptor gene repertoire in vertebrates.
Conserved synteny between the Fugu and human PTEN locus and the evolutionary conservation of vertebrate PTEN function.
Genomic structure and evolutionary conservation of the tyrosinase gene family from Fugu.
Identification and characterization of suppressor of cytokine signaling 3 (SOCS-3) homologues in teleost fish.
Four natriuretic peptides (ANP, BNP, VNP and CNP) coexist in the sturgeon: identification of BNP in fish lineage.
Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain.
The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.
Molecular evolution of the reactive oxygen-generating NADPH oxidase (Nox/Duox) family of enzymes.
Genomic characterization of the Neurofibromatosis Type 1 gene of Fugu rubripes.
Duplication, degeneration and subfunctionalization of the nested synapsin-Timp genes in Fugu.
A Tudor protein with multiple SNc domains from pea seedlings: cellular localization, partial characterization, sequence analysis, and phylogenetic relationships.
Structural analysis of cDNAs coding for 4SNc-Tudor domain protein from fish and their expression in yellowtail organs.
Identification of Jade1, a gene encoding a PHD zinc finger protein, in a gene trap mutagenesis screen for genes involved in anteroposterior axis development.
Molecular Cloning and Characterization of Carbonic Anhydrase XII from Pufferfish (Takifugu rubripes).
Identification and characterization of a beta proteasome subunit cluster in the Japanese pufferfish (Fugu rubripes).
Genomic organization, transcript variants and comparative analysis of the human nucleoporin 155 (NUP155) gene.
Structural and functional analysis of the putative pH sensor in the Kir1.1 (ROMK) potassium channel.
Identification and characterization of suppressor of cytokine signaling 1 (SOCS-1) homologues in teleost fish.
Molecular cloning of major histocompatibility complex class I cDNAs from the pufferfish Fugu rubripes.
Conservation, duplication and divergence of the zebrafish stat5 genes.
Molecular cloning and characterization of the Fugu rubripes MEST/COPG2 imprinting cluster and chromosomal localization in Fugu and Tetraodon nigroviridis.
Structural, gene expression, and functional analysis of the fugu (Takifugu rubripes) insulin-like growth factor binding protein-4 gene.
Genomic structure and expression of parathyroid hormone-related protein gene (PTHrP) in a teleost, Fugu rubripes.