The complete genome sequence of Haloferax volcanii DS2, a model archaeon.
Phylogenetically driven sequencing of extremely halophilic archaea reveals strategies for static and dynamic osmo-response.
Archaeal JAB1/MPN/MOV34 metalloenzyme (HvJAMM1) cleaves ubiquitin-like small archaeal modifier proteins (SAMPs) from protein-conjugates.
Archaeal ubiquitin-like SAMP3 is isopeptide-linked to proteins via a UbaA-dependent mechanism.
Crystal structure of ubiquitin-like small archaeal modifier protein 1 (SAMP1) from Haloferax volcanii.
E1- and ubiquitin-like proteins provide a direct link between protein conjugation and sulfur transfer in archaea.
Ubiquitin-like small archaeal modifier proteins (SAMPs) in Haloferax volcanii.
D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii.
XacR - a novel transcriptional regulator of D-xylose and L-arabinose catabolism in the haloarchaeon Haloferax volcanii.
Development of additional selectable markers for the halophilic archaeon Haloferax volcanii based on the leuB and trpA genes.
Genes for tryptophan biosynthesis in the archaebacterium Haloferax volcanii.
Evolutionary relationships of bacterial and archaeal glutamine synthetase genes.
Conserved sequence elements involved in regulation of ribosomal protein gene expression in halophilic archaea.
Genes for tryptophan biosynthesis in the halophilic archaebacterium Haloferax volcanii: the trpDFEG cluster.
Two distinct N-glycosylation pathways process the Haloferax volcanii S-layer glycoprotein upon changes in environmental salinity.
Distinct glycan-charged phosphodolichol carriers are required for the assembly of the pentasaccharide N-linked to the Haloferax volcanii S-layer glycoprotein.
Haloferax volcanii AglB and AglD are involved in N-glycosylation of the S-layer glycoprotein and proper assembly of the surface layer.
Identification of residues important for the activity of Haloferax volcanii AglD, a component of the archaeal N-glycosylation pathway.
N-glycosylation of Haloferax volcanii flagellins requires known Agl proteins and is essential for biosynthesis of stable flagella.
CetZ tubulin-like proteins control archaeal cell shape.
Citrate synthase from Haloferax volcanii: enzyme purification and gene cloning.
Expression, reactivation, and purification of enzymes from Haloferax volcanii in Escherichia coli.
Uptake of D-xylose and L-arabinose in Haloferax volcanii involves an ABC transporter of the CUT1 subfamily.
Nucleotide sequence of the ATPase A- and B-subunits of the halophilic archaebacterium Haloferax volcanii and characterization of the enzyme.
Differential regulation of the PanA and PanB proteasome-activating nucleotidase and 20S proteasomal proteins of the haloarchaeon Haloferax volcanii.
Halophilic 20S proteasomes of the archaeon Haloferax volcanii: purification, characterization, and gene sequence analysis.
Posttranslational modification of the 20S proteasomal proteins of the archaeon Haloferax volcanii.
Proteasomal components required for cell growth and stress responses in the haloarchaeon Haloferax volcanii.
Subunit topology of two 20S proteasomes from Haloferax volcanii.
Parallel evolution of non-homologous isofunctional enzymes in methionine biosynthesis.
Homologs of aquifex aeolicus protein-only RNase P are not the major RNase P activities in the archaea haloferax volcanii and methanosarcina mazei.
Fructose degradation in the haloarchaeon Haloferax volcanii involves a bacterial type phosphoenolpyruvate-dependent phosphotransferase system, fructose-1-phosphate kinase, and class II fructose-1,6-bisphosphate aldolase.
A Gateway platform for functional genomics in Haloferax volcanii: deletion of three tRNA modification genes.
Biosynthesis of 7-deazaguanosine-modified tRNA nucleosides: a new role for GTP cyclohydrolase I.
Anaerobic Growth of Haloarchaeon Haloferax volcanii by Denitrification Is Controlled by the Transcription Regulator NarO.
A predicted geranylgeranyl reductase reduces the omega-position isoprene of dolichol phosphate in the halophilic archaeon, Haloferax volcanii.
Genetic and biochemical analysis of the twin-arginine translocation pathway in halophilic archaea.
GlpR represses fructose and glucose metabolic enzymes at the level of transcription in the haloarchaeon Haloferax volcanii.
Phosphorylation and methylation of proteasomal proteins of the haloarcheon Haloferax volcanii.
The archaeal Xpf/Mus81/FANCM homolog Hef and the Holliday junction resolvase Hjc define alternative pathways that are essential for cell viability in Haloferax volcanii.
Crystal structures of a halophilic archaeal malate synthase from Haloferax volcanii and comparisons with isoforms A and G.
Operation of glyoxylate cycle in halophilic archaea: presence of malate synthase and isocitrate lyase in Haloferax volcanii.
Sequencing, phylogenetic and transcriptional analysis of the glyoxylate bypass operon (ace) in the halophilic archaeon Haloferax volcanii.
N-glycosylation in Archaea: on the coordinated actions of Haloferax volcanii AglF and AglM.
Archaeal Tuc1/Ncs6 homolog required for wobble uridine tRNA thiolation is associated with ubiquitin-proteasome, translation, and RNA processing system homologs.
Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes.
Activity and transcriptional regulation of bacterial protein-like glycerol-3-phosphate dehydrogenase of the haloarchaea in Haloferax volcanii.
Identification and characterization of 2-keto-3-deoxygluconate kinase and 2-keto-3-deoxygalactonate kinase in the haloarchaeon Haloferax volcanii.
Characterization of a pentonolactonase involved in D-xylose and L-arabinose catabolism in the haloarchaeon Haloferax volcanii.
AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein.
Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax volcanii, Suggesting Roles in Motility Regulation.
Development of a gene knockout system for the halophilic archaeon Haloferax volcanii by use of the pyrE gene.
Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination.
Archaeal and bacterial SecD and SecF homologs exhibit striking structural and functional conservation.
In vivo analysis of an essential archaeal signal recognition particle in its native host.
Reconstitution of the signal recognition particle of the halophilic archaeon Haloferax volcanii.
SRP19 is a dispensable component of the signal recognition particle in Archaea.
ATP- and NAD+-dependent DNA ligases share an essential function in the halophilic archaeon Haloferax volcanii.
Cell division in the archaeon Haloferax volcanii relies on two FtsZ proteins with distinct functions in division ring assembly and constriction.
FtsZ ring: the eubacterial division apparatus conserved in archaebacteria.
The archaeal protein SepF is essential for cell division in Haloferax volcanii.
Crystal structure of the ubiquitin-like small archaeal modifier protein 2 from Haloferax volcanii.
Biochemical characterisation of LigN, an NAD+-dependent DNA ligase from the halophilic euryarchaeon Haloferax volcanii that displays maximal in vitro activity at high salt concentrations.
AglF, aglG and aglI, novel members of a gene island involved in the N-glycosylation of the Haloferax volcanii S-layer glycoprotein.
Assembling Glycan-Charged Dolichol Phosphates: Chemoenzymatic Synthesis of a Haloferax volcanii N-Glycosylation Pathway Intermediate.
An archaeal immune system can detect multiple protospacer adjacent motifs (PAMs) to target invader DNA.
Transcriptional regulation of dimethyl sulfoxide respiration in a haloarchaeon, Haloferax volcanii.
The oxidative pentose phosphate pathway in the haloarchaeon Haloferax volcanii involves a novel type of glucose-6-phosphate dehydrogenase -- The archaeal Zwischenferment.
Archaeal inorganic pyrophosphatase displays robust activity under high-salt conditions and in organic solvents.
An alternative pathway for reduced folate biosynthesis in bacteria and halophilic archaea.
Dihydrofolate reductase of the extremely halophilic archaebacterium Halobacterium volcanii. The enzyme and its coding gene.
NMR-derived folate-bound structure of dihydrofolate reductase 1 from the halophile Haloferax volcanii.
Structural features of halophilicity derived from the crystal structure of dihydrofolate reductase from the Dead Sea halophilic archaeon, Haloferax volcanii.
Structure in an extreme environment: NMR at high salt.
SufS protein from Haloferax volcanii involved in Fe-S cluster assembly in haloarchaea.
A complex of Cas proteins 5, 6, and 7 is required for the biogenesis and stability of clustered regularly interspaced short palindromic repeats (CRISPR)-derived RNAs (crRNAs) in Haloferax volcanii.
Construction and analysis of a recombination-deficient (radA) mutant of Haloferax volcanii.
recA-like genes from three archaean species with putative protein products similar to Rad51 and Dmc1 proteins of the yeast Saccharomyces cerevisiae.
Dihydrolipoamide dehydrogenase from Haloferax volcanii: gene cloning, complete primary structure, and comparison to other dihydrolipoamide dehydrogenases.
Dihydrolipoamide dehydrogenase from the halophilic archaebacterium Haloferax volcanii: characterization and N-terminal sequence.
3-Hydroxy-3-methylglutaryl-coenzyme A reductase from Haloferax volcanii: purification, characterization, and expression in Escherichia coli.
HMG-CoA reductase is regulated by salinity at the level of transcription in Haloferax volcanii.
Mevinolin-resistant mutations identify a promoter and the gene for a eukaryote-like 3-hydroxy-3-methylglutaryl-coenzyme A reductase in the archaebacterium Haloferax volcanii.
Characterization of a gene involved in histidine biosynthesis in Halobacterium (Haloferax) volcanii: isolation and rapid mapping by transformation of an auxotroph with cosmid DNA.
Bacterioopsin-mediated regulation of bacterioruberin biosynthesis in Halobacterium salinarum.
Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway.
Conserved active site cysteine residue of archaeal THI4 homolog is essential for thiamine biosynthesis in Haloferax volcanii.
Comparative analysis of the protein components from 5S rRNA.protein complexes of halophilic archaebacteria.
Discovery and characterization of an amidinotransferase involved in the modification of archaeal tRNA.
Biological functions, genetic and biochemical characterization, and NMR structure determination of the small zinc finger protein HVO_2753 from Haloferax volcanii.
Membrane binding of SRP pathway components in the halophilic archaea Haloferax volcanii.
Expression and heat-responsive regulation of a TFIIB homologue from the archaeon Haloferax volcanii.
A novel archaeal DNA repair factor that acts with the UvrABC system to repair mitomycin C-induced DNA damage in a PCNA-dependent manner.
Genetic identification of three ABC transporters as essential elements for nitrate respiration in Haloferax volcanii.
A tRNA(Trp) intron endonuclease from Halobacterium volcanii. Unique substrate recognition properties.
Properties of H. volcanii tRNA intron endonuclease reveal a relationship between the archaeal and eucaryal tRNA intron processing systems.
Recognition of exon-intron boundaries by the Halobacterium volcanii tRNA intron endonuclease.
Isocitrate dehydrogenases from Haloferax volcanii and Sulfolobus solfataricus: enzyme purification, characterisation and N-terminal sequence.
NADP-dependent isocitrate dehydrogenase from the halophilic archaeon Haloferax volcanii: cloning, sequence determination and overexpression in Escherichia coli.
The N-terminal penultimate residue of 20S proteasome alpha1 influences its N(alpha) acetylation and protein levels as well as growth rate and stress responses of Haloferax volcanii.
Haloferax volcanii cells lacking the flagellin FlgA2 are hypermotile.
Haloferax volcanii flagella are required for motility but are not involved in PibD-dependent surface adhesion.
Role of flagellins from A and B loci in flagella formation of Halobacterium salinarum.
Expression in Haloferax volcanii of 3-hydroxy-3-methylglutaryl coenzyme A synthase facilitates isolation and characterization of the active form of a key enzyme required for polyisoprenoid cell membrane biosynthesis in halophilic archaea.
Cyclic nucleotides in archaea: Cyclic di-AMP in the archaeon Haloferax volcanii and its putative role.
Isolation of fusion proteins containing SecY and SecE, components of the protein translocation complex from the halophilic archaeon Haloferax volcanii.
Archaeosortases and exosortases are widely distributed systems linking membrane transit with posttranslational modification.
ArtA-dependent processing of a Tat substrate containing a conserved tripartite structure that is not localized at the C terminus.
Conserved residues are critical for Haloferax volcanii archaeosortase catalytic activity: implications for convergent evolution of the catalytic mechanisms of non-homologous sortases from archaea and bacteria.
Haloferax volcanii archaeosortase is required for motility, mating, and C-terminal processing of the S-layer glycoprotein.
Permuting the PGF signature motif blocks both archaeosortase-dependent C-terminal cleavage and prenyl lipid attachment for the Haloferax volcanii S-layer glycoprotein.
Characterization of paralogous and orthologous members of the superoxide dismutase gene family from genera of the halophilic archaebacteria.
Solution Structure and Dynamics of the Small Protein HVO_2922 from Haloferax volcanii.
Identification of the enzyme responsible for N1-methylation of pseudouridine 54 in archaeal tRNAs.
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA.
Biosynthesis of archaeosine, a novel derivative of 7-deazaguanosine specific to archaeal tRNA, proceeds via a pathway involving base replacement on the tRNA polynucleotide chain.
Dihydroxyacetone metabolism in Haloferax volcanii.
Glycerol-mediated repression of glucose metabolism and glycerol kinase as the sole route of glycerol catabolism in the haloarchaeon Haloferax volcanii.
L-Arabinose degradation pathway in the haloarchaeon Haloferax volcanii involves a novel type of L-arabinose dehydrogenase.