The genome sequence of the thermoacidophilic scavenger Thermoplasma acidophilum.
Characterization of NADP+-specific L-rhamnose dehydrogenase from the thermoacidophilic Archaeon Thermoplasma acidophilum.
The 1.8-A crystal structure of the N-terminal domain of an archaeal MCM as a right-handed filament.
Solution structure of the hypothetical protein TA0095 from Thermoplasma acidophilum: a novel superfamily with a two-layer sandwich architecture.
C-terminal tail derived from the neighboring subunit is critical for the activity of Thermoplasma acidophilum D-aldohexose dehydrogenase.
Structural insights into unique substrate selectivity of Thermoplasma acidophilum D-aldohexose dehydrogenase.
A histone-like protein (HTa) from Thermoplasma acidophilum. I. Purification and properties.
A histone-like protein (HTa) from Thermoplasma acidophilum. II. Complete amino acid sequence.
Thermoplasma acidophilum histone-like protein. Partial amino acid sequence suggestive of homology to eukaryotic histones.
Enzyme genomics: application of general enzymatic screens to discover new enzymes.
Structure- and function-based characterization of a new phosphoglycolate phosphatase from Thermoplasma acidophilum.
Glyceraldehyde dehydrogenases from the thermoacidophilic euryarchaeota Picrophilus torridus and Thermoplasma acidophilum, key enzymes of the non-phosphorylative Entner-Doudoroff pathway, constitute a novel enzyme family within the aldehyde dehydrogenase superfamily.
Identification and characterization of Thermoplasma acidophilum glyceraldehyde dehydrogenase: a new class of NADP+-specific aldehyde dehydrogenase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
Acta Crystallogr. F Struct. Biol. Commun.
Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved alpha+beta core domain and an auxiliary C-terminal treble-clef zinc finger.
Purification and properties of pyruvate kinase from Thermoplasma acidophilum.
A unique lipoylation system in the Archaea. Lipoylation in Thermoplasma acidophilum requires two proteins.
Crystal structure of lipoate-protein ligase A bound with the activated intermediate. Insights into interaction with lipoyl domains.
Structure of a putative lipoate protein ligase from Thermoplasma acidophilum and the mechanism of target selection for post-translational modification.
The Thermoplasma acidophilum LplA-LplB complex defines a new class of bipartite lipoate-protein ligases.
Crystal structure of Thermoplasma acidophilum XerA recombinase shows large C-shape clamp conformation and cis-cleavage mode for nucleophilic tyrosine.
Solution structure of TA0895, a MoaD homologue from Thermoplasma acidophilum.
Stimulation of MCM helicase activity by a Cdc6 protein in the archaeon Thermoplasma acidophilum.
Thermoplasma acidophilum Cdc6 protein stimulates MCM helicase activity by regulating its ATPase activity.
Moonlighting glutamate formiminotransferases can functionally replace 5-formyltetrahydrofolate cycloligase.
Cloning, sequencing and expression of the gene encoding glucose dehydrogenase from the thermophilic archaeon Thermoplasma acidophilum.
Purification and characterization of glucose dehydrogenase from the thermoacidophilic archaebacterium Thermoplasma acidophilum.
Broad-substrate screen as a tool to identify substrates for bacterial Gcn5-related N-acetyltransferases with unknown substrate specificity.
(R)-mevalonate 3-phosphate is an intermediate of the mevalonate pathway in Thermoplasma acidophilum.
Evidence of a novel mevalonate pathway in archaea.
Structural analysis of mevalonate-3-kinase provides insight into the mechanisms of isoprenoid pathway decarboxylases.
Citrate synthase from the thermophilic archaebacterium Thermoplasma acidophilium. Cloning and sequencing of the gene.
The crystal structure of citrate synthase from the thermophilic archaeon, Thermoplasma acidophilum.
An adaptation to life in acid through a novel mevalonate pathway.
Characterization of cofactor-dependent and cofactor-independent phosphoglycerate mutases from Archaea.
Nucleotide sequence of the genes encoding the subunits H, B, A' and A'' of the DNA-dependent RNA polymerase and the initiator tRNA from Thermoplasma acidophilum.
Crystal structure of the thermosome, the archaeal chaperonin and homolog of CCT.
Primary structure of the thermosome from Thermoplasma acidophilum.
Structure of the substrate binding domain of the thermosome, an archaeal group II chaperonin.
The thermosome of Thermoplasma acidophilum and its relationship to the eukaryotic chaperonin TRiC.
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum.
Characterization of thermophilic archaeal isopentenyl phosphate kinases.
X-ray structures of isopentenyl phosphate kinase.
Characterization of the DNA gyrase from the thermoacidophilic archaeon Thermoplasma acidophilum.
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine.
Phylogenetic analysis of 70 kD heat shock protein sequences suggests a chimeric origin for the eukaryotic cell nucleus.
Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum.
Structural and functional insights into Dom34, a key component of no-go mRNA decay.
Toxin-antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes.
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.
Cloning and sequencing of the gene encoding the large (alpha-) subunit of the proteasome from Thermoplasma acidophilum.
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4-A resolution.
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry.
Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMR.
Interactions of PAN's C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions.
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases.
Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum.
Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes.
Structural models for interactions between the 20S proteasome and its PAN/19S activators.
Subunit stoichiometry and three-dimensional arrangement in proteasomes from Thermoplasma acidophilum.
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.
The Thermoplasma acidophilum rpl15 gene encodes a homologue of eukaryotic ribosomal proteins L15/YL10.
Structural and biochemical analysis of a type II free methionine-R-sulfoxide reductase from Thermoplasma acidophilum.
The B12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: an evolutionary solution to the ribonucleotide reductase conundrum.
Crystal structure and molecular modeling study of N-carbamoylsarcosine amidase Ta0454 from Thermoplasma acidophilum.
Cloning and characterization of ftsZ and pyrF from the archaeon Thermoplasma acidophilum.
Crystal structures of the tricorn interacting factor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations.
The role of tricorn protease and its aminopeptidase-interacting factors in cellular protein degradation.
Mutational analysis of conserved AAA+ residues in the archaeal Lon protease from Thermoplasma acidophilum.
The Thermoplasma acidophilum Lon protease has a Ser-Lys dyad active site.
Identification of a radical SAM enzyme involved in the synthesis of archaeosine.
Cloning and sequencing of the fus-gene encoding elongation factor 2 in the archaebacterium Thermoplasma acidophilum.
Solution structure of the hypothetical novel-fold protein TA0956 from Thermoplasma acidophilum.
Biosynthesis of archaeal membrane lipids: digeranylgeranylglycerophospholipid reductase of the thermoacidophilic archaeon Thermoplasma acidophilum.
Insights into substrate specificity of geranylgeranyl reductases revealed by the structure of digeranylgeranylglycerophospholipid reductase, an essential enzyme in the biosynthesis of archaeal membrane lipids.
Stereochemistry of reduction in digeranylgeranylglycerophospholipid reductase involved in the biosynthesis of archaeal membrane lipids from Thermoplasma acidophilum.
Crystal structure of the hypothetical protein TA1238 from Thermoplasma acidophilum: a new type of helical super-bundle.
A broad specificity nucleoside kinase from Thermoplasma acidophilum.
Cloning and sequencing of the gene for the cytoplasmic inorganic pyrophosphatase from the thermoacidophilic archaebacterium Thermoplasma acidophilum.
Purification and enzymic characterization of the cytoplasmic pyrophosphatase from the thermoacidophilic archaebacterium Thermoplasma acidophilum.
Cloning and sequencing of the gene coding for the elongation factor 1 alpha from the archaebacterium Thermoplasma acidophilum.
Autocatalytic processing of the 20S proteasome.
Primary structure of the Thermoplasma proteasome and its implications for the structure, function, and evolution of the multicatalytic proteinase.
Proteasome from Thermoplasma acidophilum: a threonine protease.
Novel zinc-containing ferredoxin family in thermoacidophilic archaea.
Structural conservation of the isolated zinc site in archaeal zinc-containing ferredoxins as revealed by X-ray absorption spectroscopic analysis and its evolutionary implications.
Nucleotide sequence of the gene coding for ribosomal protein S10 from the archaeum Thermoplasma acidophilum.
The catalytic core of an archaeal 2-oxoacid dehydrogenase multienzyme complex is a 42-mer protein assembly.
Why are the 2-oxoacid dehydrogenase complexes so large? Generation of an active trimeric complex.
The structural basis for methylmalonic aciduria. The crystal structure of archaeal ATP:cobalamin adenosyltransferase.
NMR structure of the conserved novel-fold protein TA0743 from Thermoplasma acidophilum.
An actin homolog of the archaeon Thermoplasma acidophilum that retains the ancient characteristics of eukaryotic actin.
Crystal structure of an archaeal actin homolog.
Thioredoxin reductase from Thermoplasma acidophilum: a new twist on redox regulation.
The intein of the Thermoplasma A-ATPase A subunit: structure, evolution and expression in E. coli.
Structural analysis and insight into metal-ion activation of the iron-dependent regulator from Thermoplasma acidophilum.
Nucleotide sequence of a putative succinate dehydrogenase operon in Thermoplasma acidophilum.
Beta-propeller repeats and a PDZ domain in the Tricorn protease: predicted self-compartmentalisation and C-terminal polypeptide-binding strategies of substrate selection.
Capsids of Tricorn protease studied by electron cryomicroscopy.
Crystal structure of the tricorn protease reveals a protein disassembly line.
Navigation inside a protease: substrate selection and product exit in the tricorn protease from Thermoplasma acidophilum.
Purification, crystallization, and preliminary X-ray diffraction analysis of the Tricorn protease hexamer from Thermoplasma acidophilum.
Tricorn protease -- the core of a modular proteolytic system.
Tricorn protease exists as an icosahedral supermolecule in vivo.
Cloning, sequencing and expression of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum.
Structure of VAT, a CDC48/p97 ATPase homologue from the archaeon Thermoplasma acidophilum as studied by electron tomography.