Comparative genomics of trypanosomatid parasitic protozoa.
The genome of the African trypanosome Trypanosoma brucei.
The DNA sequence of chromosome I of an African trypanosome: gene content, chromosome organisation, recombination and polymorphism.
Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mitoribosomal small subunit maturation involves formation of initiation-like complexes.
The RNA-associated proteins MKT1 and MKT1L form alternative PBP1-containing complexes in Trypanosoma brucei.
Trypanosome MKT1 and the RNA-binding protein ZC3H11: interactions and potential roles in post-transcriptional regulatory networks.
Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase.
Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome.
The GTPase IFT27 is involved in both anterograde and retrograde intraflagellar transport.
Crystal structure of an arginase-like protein from Trypanosoma brucei that evolved without a binuclear manganese cluster.
Structures of the T.brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold.
Structures of the T. brucei kRNA editing factor MRB1590 reveal unique RNA-binding pore motif contained within an ABC-ATPase fold.
Crystal structure of arginine methyltransferase 6 from Trypanosoma brucei.
Structural Analysis of the 42 kDa Parvulin of Trypanosoma brucei.
Solution structure of SUMO from Trypanosoma brucei and its interaction with Ubc9.
The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists.
A repetitive protein essential for the flagellum attachment zone filament structure and function in Trypanosoma brucei.
Structural studies of the shortest extended synaptotagmin with only two C2 domains from Trypanosoma brucei.
Using fragment cocktail crystallography to assist inhibitor design of Trypanosoma brucei nucleoside 2-deoxyribosyltransferase.
Structures of purine nucleosidase from Trypanosoma brucei bound to isozyme-specific trypanocidals and a novel metalorganic inhibitor.
Relief of autoinhibition by conformational switch explains enzyme activation by a catalytically dead paralog.
Species-Selective Pyrimidineamine Inhibitors of Trypanosoma brucei S-Adenosylmethionine Decarboxylase.
Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit.
PIG-M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER.
Native Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing.
Protein features for assembly of the RNA editing helicase 2 subcomplex (REH2C) in Trypanosome holo-editosomes.
REH2 RNA helicase in kinetoplastid mitochondria: ribonucleoprotein complexes and essential motifs for unwinding and guide RNA (gRNA) binding.
REH2C Helicase and GRBC Subcomplexes May Base Pair through mRNA and Small Guide RNA in Kinetoplastid Editosomes.
Crystal structure of a heterodimer of editosome interaction proteins in complex with two copies of a cross-reacting nanobody.
Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds.
Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies.
ATP synthase from Trypanosoma brucei has an elaborated canonical F1-domain and conventional catalytic sites.
A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies.
Spliceosomal proteomics in Trypanosoma brucei reveal new RNA splicing factors.
Crystal structures of trypanosomal histidyl-tRNA synthetase illuminate differences between eukaryotic and prokaryotic homologs.