9940:HCRTR1
gene id: 9940:HCRTR1
uniprot id: W5NTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:VXN
gene id: 9940:VXN
uniprot id: A0A836ACE5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104808
gene id: 9940:LOC101104808
uniprot id: W5Q416
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9940:TPST2
gene id: 9940:TPST2
uniprot id: A0A6P3T242
uniprot id: W5NTR0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBCK1
gene id: 9940:RBCK1
uniprot id: W5QCS0
names: Similarity
messages: Belongs to the RBR family.

9940:BSCL2
gene id: 9940:BSCL2
uniprot id: A0A835ZTH6
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARMCX3
gene id: 9940:ARMCX3
uniprot id: A0A835ZKA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ESRRG
gene id: 9940:ESRRG
uniprot id: W5PNX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9940:ING2
gene id: 9940:ING2
uniprot id: W5PB66
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9940:BEX5
gene id: 9940:BEX5
uniprot id: A0A6P3ENF1
names: Similarity
messages: Belongs to the BEX family.

9940:SPTLC1
gene id: 9940:SPTLC1
uniprot id: A0A6P3E0Y3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CARMIL1
gene id: 9940:CARMIL1
uniprot id: W5P1B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

9940:ASB17
gene id: 9940:ASB17
uniprot id: A0A6P3E6K4
uniprot id: W5PTC6
names: Caution
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113259
gene id: 9940:LOC101113259
uniprot id: A0A6P3EBZ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114793
gene id: 9940:LOC101114793
uniprot id: A0A6P3TRH2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118455
gene id: 9940:LOC101118455
uniprot id: W5P4B0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9940:CFAP20
gene id: 9940:CFAP20
uniprot id: A0A6P3EJG7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERAP1
gene id: 9940:ERAP1
uniprot id: W5Q8S5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9940:TBRG1
gene id: 9940:TBRG1
uniprot id: A0A6P3EK09
uniprot id: W5PKT8
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC106990881
gene id: 9940:LOC106990881
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BACE2
gene id: 9940:BACE2
uniprot id: W5PK88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane

9940:NDUFAF4
gene id: 9940:NDUFAF4
uniprot id: A0A6P3EFV5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC77
gene id: 9940:CCDC77
uniprot id: A0A6P3TQR7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM183A
gene id: 9940:TMEM183A
uniprot id: W5NR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

9940:AP4S1
gene id: 9940:AP4S1
uniprot id: W5P7C9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9940:FIGN
gene id: 9940:FIGN
uniprot id: W5P7F0
names: Similarity
messages: Belongs to the AAA ATPase family.

9940:TMEM38A
gene id: 9940:TMEM38A
uniprot id: A0A6P3EDH3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HMGCR
gene id: 9940:HMGCR
uniprot id: A0A6P7E814
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane

9940:KATNBL1
gene id: 9940:KATNBL1
uniprot id: A0A6P7DW96
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MGST2
gene id: 9940:MGST2
uniprot id: W5PTY0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9940:KCNK7
gene id: 9940:KCNK7
uniprot id: W5Q3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9940:URM1
gene id: 9940:URM1
uniprot id: A0A6P3E9J3
uniprot id: W5PKI4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BPGM
gene id: 9940:BPGM
uniprot id: A0A6P3TG89
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9940:WASF1
gene id: 9940:WASF1
uniprot id: A0A6P3E8H0
uniprot id: W5PKA3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:NFIA
gene id: 9940:NFIA
uniprot id: A0A6P3DYV1
uniprot id: W5PGE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TREX2
gene id: 9940:TREX2
uniprot id: A0A836CSF5
names: Caution
names: Similarity
messages: Belongs to the exonuclease superfamily. TREX family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122717
gene id: 9940:LOC101122717
uniprot id: W5P456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9940:FKBP6
gene id: 9940:FKBP6
uniprot id: W5PTI8
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

9940:GET1
gene id: 9940:GET1
uniprot id: A0A836AQC2
uniprot id: W5PIY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MLLT1
gene id: 9940:MLLT1
uniprot id: A0A6P3YLP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AZIN1
gene id: 9940:AZIN1
uniprot id: A0A836CZ70
names: Caution
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLA2G4A
gene id: 9940:PLA2G4A
uniprot id: A0A6P3EJX2
uniprot id: W5PDL0
names: Caution
names: Domain
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC91
gene id: 9940:CCDC91
uniprot id: A0A6P3YIS7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GALNT3
gene id: 9940:GALNT3
uniprot id: W5P510
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9940:SLAMF7
gene id: 9940:SLAMF7
uniprot id: A0A6P3TK83
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLRX
gene id: 9940:GLRX
uniprot id: B2ZA84
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

9940:LOC101102551
gene id: 9940:LOC101102551
uniprot id: W5Q872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PJVK
gene id: 9940:PJVK
uniprot id: W5Q787
names: Similarity
messages: Belongs to the gasdermin family.

9940:BPI
gene id: 9940:BPI
uniprot id: T2FG11
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Cytoplasmic granule membrane
messages: Membrane
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

9940:GPAT4
gene id: 9940:GPAT4
uniprot id: A0A6P3EER8
uniprot id: W5NWR4
names: Caution
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A2
gene id: 9940:SLC39A2
uniprot id: C7BDW0
names: Subcellular Location Annotation
messages: Membrane

9940:LOC101103482
gene id: 9940:LOC101103482
uniprot id: W5NWQ6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:ENDOG
gene id: 9940:ENDOG
uniprot id: W5PHY0
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9940:VPS50
gene id: 9940:VPS50
uniprot id: A0A6P3E4G8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN12
gene id: 9940:CLDN12
uniprot id: A0A6P3E3V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

9940:CC2D1B
gene id: 9940:CC2D1B
uniprot id: A0A6P3TJQ6
names: Similarity
messages: Belongs to the CC2D1 family.

9940:CCR3
gene id: 9940:CCR3
uniprot id: Q9N0M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:WDR45
gene id: 9940:WDR45
uniprot id: A0A6P3ESE9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104205
gene id: 9940:LOC101104205
uniprot id: W5P812
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

9940:SPARC
gene id: 9940:SPARC
uniprot id: A0A6P3CXP3
uniprot id: A0A6P3TLP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
messages: Belongs to the SPARC family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: basement membrane

9940:RLBP1
gene id: 9940:RLBP1
uniprot id: A0A835ZQI3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYOD1
gene id: 9940:MYOD1
uniprot id: A0A836CVY1
uniprot id: P29331
names: Caution
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by a complex containing EP300 and PCAF. The acetylation is essential to activate target genes. Conversely, its deacetylation by SIRT1 inhibits its function (By similarity).
messages: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2. Interacts with SUV39H1. Interacts with DDX5. Interacts with CHD2. Interacts with TSC22D3 (By similarity). Interacts with SETD3 (By similarity). Interacts with P-TEFB complex; promotes the transcriptional activity of MYOD1 through its CDK9-mediated phosphorylation (By similarity). Interacts with CSRP3 (By similarity). Interacts with NUPR1 (By similarity).
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Methylation at Lys-104 by EHMT2/G9a inhibits myogenic activity.
messages: Nucleus
messages: Phosphorylated by CDK9. This phosphorylation promotes its function in muscle differentiation (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitinated on the N-terminus; which is required for proteasomal degradation.

9940:VEGFA
gene id: 9940:VEGFA
uniprot id: P50412
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity). Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (By similarity).
messages: Homodimer; disulfide-linked (By similarity). Also found as heterodimer with PGF (By similarity). Interacts with NRP1 (By similarity). Interacts with BSG (By similarity).

9940:CIDEC
gene id: 9940:CIDEC
uniprot id: A0A835ZW13
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:JAKMIP2
gene id: 9940:JAKMIP2
uniprot id: W5P0N2
names: Similarity
messages: Belongs to the JAKMIP family.

9940:NFYB
gene id: 9940:NFYB
uniprot id: A0A6P3TLW9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.
messages: Heterotrimeric transcription factor composed of three components, NF-YA, NF-YB and NF-YC. NF-YB and NF-YC must interact and dimerize for NF-YA association and DNA binding. Interacts with C1QBP.

9940:PURA
gene id: 9940:PURA
uniprot id: Q9MYX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9940:EFS
gene id: 9940:EFS
uniprot id: W5QDG5
names: Similarity
messages: Belongs to the CAS family.

9940:LOC101109892
gene id: 9940:LOC101109892
uniprot id: A0A6P7EIW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:VDAC1
gene id: 9940:VDAC1
uniprot id: A0A6P7EFR0
uniprot id: B2LYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

9940:LGMN
gene id: 9940:LGMN
uniprot id: W5PUH5
names: Similarity
messages: Belongs to the peptidase C13 family.

9940:SFR1
gene id: 9940:SFR1
uniprot id: W5P8V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

9940:GDF10
gene id: 9940:GDF10
uniprot id: W5NSY5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

9940:CDC42BPA
gene id: 9940:CDC42BPA
uniprot id: W5NW15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm
messages: lamellipodium

9940:DPM3
gene id: 9940:DPM3
uniprot id: A0A836AGQ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM3 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1H1orf141
gene id: 9940:C1H1orf141
uniprot id: A0A6P3TAP8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPA
gene id: 9940:COPA
uniprot id: A0A6P3E7F4
uniprot id: W5PFV7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MBOAT4
gene id: 9940:MBOAT4
uniprot id: K9MH73
names: Subcellular Location Annotation
messages: Membrane

9940:RELN
gene id: 9940:RELN
uniprot id: A0A067YHI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

9940:LOC100135455
gene id: 9940:LOC100135455
uniprot id: A0A6P9FQR6
names: Similarity
messages: Belongs to the TCTP family.

9940:APOBEC3A
gene id: 9940:APOBEC3A
uniprot id: B7T159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Nucleus
messages: P-body

9940:LOC101117542
gene id: 9940:LOC101117542
uniprot id: A0A835ZYG0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OLFM4
gene id: 9940:OLFM4
uniprot id: W5P9S6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:ELAVL3
gene id: 9940:ELAVL3
uniprot id: W5QAS8
names: Similarity
messages: Belongs to the RRM elav family.

9940:TTC39C
gene id: 9940:TTC39C
uniprot id: W5PCF6
names: Similarity
messages: Belongs to the TTC39 family.

9940:LOC101110265
gene id: 9940:LOC101110265
uniprot id: A0A836CY35
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTGS2
gene id: 9940:PTGS2
uniprot id: P79208
names: Cofactor
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated at Ser-564 by SPHK1. During neuroinflammation, acetylation by SPHK1 promotes neuronal secretion of specialized preresolving mediators (SPMs), especially 15-R-lipoxin A4, which results in an increase of phagocytic microglia.
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Conversion of arachidonate to prostaglandin H2 is mediated by 2 different isozymes: the constitutive PTGS1 and the inducible PTGS2. PTGS1 is expressed constitutively and generally produces prostanoids acutely in response to hormonal stimuli to fine-tune physiological processes requiring instantaneous, continuous regulation (e.g. hemostasis). PTGS2 is inducible and typically produces prostanoids that mediate responses to physiological stresses such as infection and inflammation.
messages: Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response (PubMed:10438452). The cyclooxygenase activity oxygenates arachidonate (AA, C20:4(n-6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide PGH2, the precursor of all 2-series prostaglandins and thromboxanes (PubMed:10438452). This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons (By similarity). Similarly catalyzes successive cyclooxygenation and peroxidation of dihomo-gamma-linoleate (DGLA, C20:3(n-6)) and eicosapentaenoate (EPA, C20:5(n-3)) to corresponding PGH1 and PGH3, the precursors of 1- and 3-series prostaglandins (By similarity). In an alternative pathway of prostanoid biosynthesis, converts 2-arachidonoyl lysophopholipids to prostanoid lysophopholipids, which are then hydrolyzed by intracellular phospholipases to release free prostanoids (By similarity). Metabolizes 2-arachidonoyl glycerol yielding the glyceryl ester of PGH2, a process that can contribute to pain response. Generates lipid mediators from n-3 and n-6 polyunsaturated fatty acids (PUFAs) via a lipoxygenase-type mechanism. Oxygenates PUFAs to hydroperoxy compounds and then reduces them to corresponding alcohols (By similarity). Plays a role in the generation of resolution phase interaction products (resolvins) during both sterile and infectious inflammation. Metabolizes docosahexaenoate (DHA, C22:6(n-3)) to 17R-HDHA, a precursor of the D-series resolvins (RvDs) (By similarity). As a component of the biosynthetic pathw…
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Microsome membrane
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: PTGS1 and PTGS2 are the targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin and ibuprofen. Aspirin is able to produce an irreversible inactivation of the enzyme through a serine acetylation. Inhibition of the PGHSs with NSAIDs acutely reduces inflammation, pain, and fever, and long-term use of these drugs reduces fatal thrombotic events, as well as the development of colon cancer and Alzheimer's disease. PTGS2 is the principal isozyme responsible for production of inflammatory prostaglandins. New generation PTGSs inhibitors strive to be selective for PTGS2, to avoid side effects such as gastrointestinal complications and ulceration.
messages: S-nitrosylation by NOS2 (iNOS) activates enzyme activity. S-nitrosylation may take place on different Cys residues in addition to Cys-525.
messages: The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2). The cyclooxygenase reaction occurs in a hydrophobic channel in the core of the enzyme. The peroxidase reaction occurs at a heme-containing active site located near the protein surface. The nonsteroidal anti-inflammatory drugs (NSAIDs) binding site corresponds to the cyclooxygenase active site.

9940:CD9
gene id: 9940:CD9
uniprot id: B0LXL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

9940:BLOC1S5
gene id: 9940:BLOC1S5
uniprot id: W5Q6I4
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

9940:MRPS24
gene id: 9940:MRPS24
uniprot id: A0A6P3EP96
uniprot id: W5PVC5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMCC3
gene id: 9940:TMCC3
uniprot id: A0A836D4Y2
uniprot id: W5Q327
names: Caution
names: Similarity
messages: Belongs to the TEX28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAPPC8
gene id: 9940:TRAPPC8
uniprot id: A0A6P3TG28
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SYTL2
gene id: 9940:SYTL2
uniprot id: A0A6P3T8C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:S100A3
gene id: 9940:S100A3
uniprot id: A0A6P3E5Z5
uniprot id: A0A6P3TJ11
names: Caution
names: Similarity
messages: Belongs to the S-100 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ABCG8
gene id: 9940:ABCG8
uniprot id: A0A6P3TJ36
uniprot id: W5P9N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9940:SMCO1
gene id: 9940:SMCO1
uniprot id: A0A6P3DZP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AMDHD1
gene id: 9940:AMDHD1
uniprot id: W5PR50
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

9940:TRPV6
gene id: 9940:TRPV6
uniprot id: A0A6P3E5A4
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEMA4D
gene id: 9940:SEMA4D
uniprot id: W5PD26
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:ZNF169
gene id: 9940:ZNF169
uniprot id: A0A6P3E6T6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP1R8
gene id: 9940:PPP1R8
uniprot id: A0A836D736
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MSRB3
gene id: 9940:MSRB3
uniprot id: A0A6P7DWT5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

9940:CCDC65
gene id: 9940:CCDC65
uniprot id: A0A6P3EBL9
uniprot id: A0A6P7DWJ7
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: flagellum axoneme

9940:LACC1
gene id: 9940:LACC1
uniprot id: W5PCC0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

9940:HDAC1
gene id: 9940:HDAC1
uniprot id: A0A6P3E958
uniprot id: W5QIG5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS5
gene id: 9940:RPS5
uniprot id: W5P114
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

9940:DUSP4
gene id: 9940:DUSP4
uniprot id: A0A6P3EEQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FPGS
gene id: 9940:FPGS
uniprot id: W5PPC9
names: Cofactor
names: Function
names: Similarity
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis.

9940:CRHBP
gene id: 9940:CRHBP
uniprot id: Q28557
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

9940:ABCF3
gene id: 9940:ABCF3
uniprot id: A0A6P3E524
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106855
gene id: 9940:LOC101106855
uniprot id: A0A836A0U0
uniprot id: W5PMC5
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104222
gene id: 9940:LOC101104222
uniprot id: W5PDX3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:CKS1B
gene id: 9940:CKS1B
uniprot id: A0A6P3YGW9
uniprot id: W5NZA3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPF19
gene id: 9940:PRPF19
uniprot id: A0A6P3EK25
uniprot id: W5Q1Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Lipid droplet
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.
messages: nucleoplasm

9940:AKAP5
gene id: 9940:AKAP5
uniprot id: W5NS86
names: Subcellular Location Annotation
messages: Membrane

9940:SGCG
gene id: 9940:SGCG
uniprot id: W5PVB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

9940:CLIC2
gene id: 9940:CLIC2
uniprot id: W5P0K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

9940:DCAF4
gene id: 9940:DCAF4
uniprot id: A0A6P3YMJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106791
gene id: 9940:LOC101106791
uniprot id: A0A6P3EM17
uniprot id: W5Q6F0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGM3
gene id: 9940:PGM3
uniprot id: W5PC32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9940:IRF2
gene id: 9940:IRF2
uniprot id: Q9N137
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:DHX35
gene id: 9940:DHX35
uniprot id: A0A6P3EJ16
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V0C
gene id: 9940:ATP6V0C
uniprot id: A0A835ZJL3
uniprot id: O18882
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment (By similarity).
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitinated by RNF182, leading to its degradation via the ubiquitin-proteasome pathway.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex (By similarity). The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H (By similarity). The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits ATP6AP1/Ac45 and ATP6AP2/PRR (By similarity). Interacts with the V0 complex V-ATPase subunit a4 ATP6V0A4 (By similarity). Interacts with LASS2 (By similarity). Interacts with RNF182; this interaction leads to ubiquitination and degradation via the proteasome pathway (By similarity).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

9940:IL27RA
gene id: 9940:IL27RA
uniprot id: A0A6P3E4G6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL10
gene id: 9940:RPL10
uniprot id: A8D8X1
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Citrullinated by PADI4.
messages: Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development.
messages: Ufmylated by UFL1.

9940:PAX2
gene id: 9940:PAX2
uniprot id: D5GSQ9
names: Subcellular Location Annotation
messages: Nucleus

9940:CSNK1G1
gene id: 9940:CSNK1G1
uniprot id: W5QHU6
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9940:PSENEN
gene id: 9940:PSENEN
uniprot id: A0A6P3ECB7
uniprot id: A0A6P3EJM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEN-2 family.
messages: Golgi stack membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM115
gene id: 9940:TMEM115
uniprot id: A0A836CSW7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ESR2
gene id: 9940:ESR2
uniprot id: Q9TU15
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer. Can form a heterodimer with ESR1. Interacts with NCOA1, NCOA3, NCOA5 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Interacts with UBE1C and AKAP13. Interacts with DNTTIP2. Interacts with CCDC62 in the presence of estradiol/E2; this interaction seems to enhance the transcription of target genes. Interacts with DNAAF4. Interacts with PRMT2. Interacts with CCAR2 (via N-terminus) in a ligand-independent manner. Interacts with RBM39, in the presence of estradiol (E2).
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.
messages: Nucleus
messages: Phosphorylation at Ser-84 and Ser-102 recruits NCOA1.

9940:NR3C2
gene id: 9940:NR3C2
uniprot id: A0A835ZQ19
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TUBA4A
gene id: 9940:TUBA4A
uniprot id: A0A6P3CX09
uniprot id: C5ISA2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9940:NDUFAF3
gene id: 9940:NDUFAF3
uniprot id: A0A6P3EPJ3
uniprot id: W5Q261
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HAUS8
gene id: 9940:HAUS8
uniprot id: A0A6P3E4E9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC5A8
gene id: 9940:SLC5A8
uniprot id: A0A6P3EAX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OCLN
gene id: 9940:OCLN
uniprot id: A0A6P3T1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

9940:MGST3
gene id: 9940:MGST3
uniprot id: A0A836D8C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCBP2
gene id: 9940:NCBP2
uniprot id: A0A6P3E6U6
uniprot id: W5QGM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDSS1
gene id: 9940:PDSS1
uniprot id: W5Q3V9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9940:UBE2D3
gene id: 9940:UBE2D3
uniprot id: A0A836A9D5
uniprot id: W5NX15
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112509
gene id: 9940:LOC101112509
uniprot id: W5Q5B9
names: Function
messages: Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle.

9940:ZBTB44
gene id: 9940:ZBTB44
uniprot id: A0A6P3YPH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK4
gene id: 9940:CDK4
uniprot id: A0A836D7X7
uniprot id: B2MVY4
uniprot id: W5P5K6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: Both phosphorylation at Thr-172 and binding of a D-type cyclin are necessary for enzymatic activity. Full activation of the cyclin-D-CDK4 complex appears to require other factors such as recruitment of the substrate via a substrate recruitment motif, and/or formation of the CDKN1B ternary complex. Inhibited by INK4 family members. In resting cells, the non-tyrosine-phosphorylated form of CDKN1B prevents phosphorylation at Thr-172 and inactivation, while, in proliferating cells, tyrosine phosphorylation of CDKN1B allows phosphorylation of Thr-172 of CDK4 and subsequennt activation.
messages: Component of the D-CDK4 complex, composed of CDK4 and some D-type G1 cyclin (CCND1, CCND2 or CCND3). Interacts directly in the complex with CCND1, CCND2 or CCND3. Interacts with SEI1 and ZNF655. Forms a ternary complex, cyclin D-CDK4-CDKN1B, involved in modulating CDK4 enzymatic activity. Interacts directly with CDKN1B (phosphorylated on 'Tyr-88' and 'Tyr-89'); the interaction allows assembly of the cyclin D-CDK4 complex, Thr-172 phosphorylation, nuclear translocation and enhances the cyclin D-CDK4 complex activity. CDK4 activity is either inhibited or enhanced depending on stoichiometry of complex. The non-tyrosine-phosphorylated form of CDKN1B prevents T-loop phosphorylation of CDK4 producing inactive CDK4. Interacts (unphosphorylated form) with CDK2. Also forms ternary complexes with CDKN1A or CDKN2A. Interacts directly with CDKN1A (via its N-terminal); the interaction promotes the assembly of the cyclin D-CDK4 complex, its nuclear translocation and promotes the cyclin D-dependent enzyme activity of CDK4. Interacts with FNIP1 and FNIP2.
messages: Cytoplasm
messages: Nucleus
messages: Nucleus membrane
messages: Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also a substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111391
gene id: 9940:LOC101111391
uniprot id: W5PCF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TMEM256
gene id: 9940:TMEM256
uniprot id: W5PU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

9940:PRP1
gene id: 9940:PRP1
uniprot id: A8QW37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9940:ROCK1
gene id: 9940:ROCK1
uniprot id: A0A6P3EG18
uniprot id: W5PGB5
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by RHOA binding. Inhibited by Y-27632.
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Homodimer.
messages: Membrane
messages: Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL6ST
gene id: 9940:IL6ST
uniprot id: W5PCA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9940:TRMT112
gene id: 9940:TRMT112
uniprot id: A0A6P3EK65
uniprot id: W5PA68
names: Caution
names: Similarity
messages: Belongs to the TRM112 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PYURF
gene id: 9940:PYURF
uniprot id: A0A6P3EDV7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118639
gene id: 9940:LOC101118639
uniprot id: W5PT87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TLR3
gene id: 9940:TLR3
uniprot id: B5DC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9940:CXCL13
gene id: 9940:CXCL13
uniprot id: A0A6P3E707
uniprot id: W5Q8I5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPR63
gene id: 9940:GPR63
uniprot id: A0A6P3E6R6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC40
gene id: 9940:CDC40
uniprot id: A0A6P3EGT5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD4
gene id: 9940:PSMD4
uniprot id: A0A6P3TJJ6
uniprot id: A7UHZ2
names: Caution
names: Similarity
messages: Belongs to the proteasome subunit S5A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZFAND6
gene id: 9940:ZFAND6
uniprot id: A0A6P3EI62
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FKBP5
gene id: 9940:FKBP5
uniprot id: A0A6P3YN75
uniprot id: A0A6P3YNB0
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GARS1
gene id: 9940:GARS1
uniprot id: W5PDU8
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

9940:TADA3
gene id: 9940:TADA3
uniprot id: W5P835
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGG1 family.
messages: Nucleus

9940:LOC101110066
gene id: 9940:LOC101110066
uniprot id: A0A6P3EBJ6
names: Caution
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OOEP
gene id: 9940:OOEP
uniprot id: U3N063
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KHDC1 family.
messages: Cytoplasm
messages: Nucleus

9940:PCMTD1
gene id: 9940:PCMTD1
uniprot id: A0A6P7ECA1
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9940:RPS4X
gene id: 9940:RPS4X
uniprot id: A0A6P3ES39
uniprot id: W5PFW3
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THOC7
gene id: 9940:THOC7
uniprot id: A0A6P3YMW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

9940:TDO2
gene id: 9940:TDO2
uniprot id: A0A835ZQN1
uniprot id: W5PAB0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARHGEF6
gene id: 9940:ARHGEF6
uniprot id: W5PMS0
names: Subcellular Location Annotation
messages: lamellipodium

9940:KATNAL2
gene id: 9940:KATNAL2
uniprot id: W5NZX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

9940:SH2D1A
gene id: 9940:SH2D1A
uniprot id: W5PXC9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2.

9940:DES
gene id: 9940:DES
uniprot id: A0A6P3E6L1
uniprot id: W5QG29
names: Caution
names: Similarity
messages: Belongs to the intermediate filament family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TOMM40
gene id: 9940:TOMM40
uniprot id: A0A836CX65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C13H20orf85
gene id: 9940:C13H20orf85
uniprot id: A0A836A5M6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111035
gene id: 9940:LOC101111035
uniprot id: W5P3F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9940:CASTOR2
gene id: 9940:CASTOR2
uniprot id: A0A6P3ELT7
names: Caution
names: Similarity
messages: Belongs to the GATS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HEPHL1
gene id: 9940:HEPHL1
uniprot id: W5NV45
names: Similarity
messages: Belongs to the multicopper oxidase family.

9940:KRT84
gene id: 9940:KRT84
uniprot id: A0A836AJA2
uniprot id: W5Q6J4
names: Caution
names: Similarity
messages: Belongs to the intermediate filament family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTN2
gene id: 9940:ACTN2
uniprot id: A0A6P3EM26
names: Caution
names: Similarity
messages: Belongs to the alpha-actinin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UTP23
gene id: 9940:UTP23
uniprot id: W5PLC6
names: Subcellular Location Annotation
messages: nucleolus

9940:EIF4G1
gene id: 9940:EIF4G1
uniprot id: A0A6P3T232
uniprot id: W5QHD4
names: Caution
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DIABLO
gene id: 9940:DIABLO
uniprot id: W5PQ00
names: Subcellular Location Annotation
messages: Mitochondrion

9940:MMP14
gene id: 9940:MMP14
uniprot id: A0A6P9FQP6
uniprot id: C8BKE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109452
gene id: 9940:LOC101109452
uniprot id: A0A6P3E892
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:P2RY1
gene id: 9940:P2RY1
uniprot id: A0A6P3E732
uniprot id: W5Q0R9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102194
gene id: 9940:LOC101102194
uniprot id: A0A6P3EKZ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATG4A
gene id: 9940:ATG4A
uniprot id: A0A6P3EHK0
uniprot id: W5QAR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AIFM1
gene id: 9940:AIFM1
uniprot id: W5Q1F6
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

9940:HEXA
gene id: 9940:HEXA
uniprot id: B2LSM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9940:ARMCX1
gene id: 9940:ARMCX1
uniprot id: A0A6P3EFE0
uniprot id: A0A6P3TLD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YIPF1
gene id: 9940:YIPF1
uniprot id: A0A6P3TI43
uniprot id: W5P9J6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9940:CRABP1
gene id: 9940:CRABP1
uniprot id: W5NRM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

9940:MINDY1
gene id: 9940:MINDY1
uniprot id: W5QIB3
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

9940:TASP1
gene id: 9940:TASP1
uniprot id: W5PN10
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9940:CPE
gene id: 9940:CPE
uniprot id: W5Q3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M14 family.
messages: Interacts with Secretogranin III/SCG3.
messages: Membrane
messages: Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage.
messages: secretory vesicle membrane

9940:LOC101112657
gene id: 9940:LOC101112657
uniprot id: A0A6P7EGP6
uniprot id: A0A6P7EH18
names: Caution
names: Function
messages: The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTB
gene id: 9940:ACTB
uniprot id: D7RIF5
uniprot id: P60713
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.
messages: Belongs to the actin family.
messages: ISGylated.
messages: In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.
messages: Methylated at His-73 by SETD3 (By similarity). Methylation at His-73 is required for smooth muscle contraction of the laboring uterus during delivery (By similarity).
messages: Monomethylation at Lys-84 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration.
messages: N-terminal acetylation by NAA80 affects actin filament depolymerization and elongation, including elongation driven by formins. In contrast, filament nucleation by the Arp2/3 complex is not affected.
messages: Nucleus
messages: Oxidation of Met-44 and Met-47 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization.
messages: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCSAM (By similarity). Interacts with TBC1D21. Interacts with CPNE1 (via VWFA domain) and CPNE4 (via VWFA domain) (By similarity). Interacts with DHX9 (via C-terminus); this interaction is direct and mediates the attachment to nuclear ribonucleoprotein complexes. Interacts with FAM107A (By similarity).
messages: cytoskeleton

9940:SGTB
gene id: 9940:SGTB
uniprot id: A0A6P3EN80
uniprot id: W5P7Z0
names: Caution
names: Similarity
messages: Belongs to the SGT family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDNF
gene id: 9940:NDNF
uniprot id: W5Q172
names: Subcellular Location Annotation
messages: Secreted

9940:NDRG2
gene id: 9940:NDRG2
uniprot id: A0A6P3YK30
uniprot id: A0A6P3YM99
uniprot id: A0A6P7E451
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OLFM3
gene id: 9940:OLFM3
uniprot id: W5QAR8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9940:MPC2
gene id: 9940:MPC2
uniprot id: W5PS50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

9940:MET
gene id: 9940:MET
uniprot id: Q09YI9
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autophosphorylated in response to ligand binding on Tyr-1235 and Tyr-1236 in the kinase domain leading to further phosphorylation of Tyr-1350 and Tyr-1357 in the C-terminal multifunctional docking site. Dephosphorylated by PTPRJ at Tyr-1350 and Tyr-1366. Dephosphorylated by PTPN1 and PTPN2 (By similarity).
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Heterodimer made of an alpha chain (50 kDa) and a beta chain (145 kDa) which are disulfide linked. Binds PLXNB1. Interacts when phosphorylated with downstream effectors including STAT3, PIK3R1, SRC, PCLG1, GRB2 and GAB1. Interacts with SPSB1, SPSB2 and SPSB4. Interacts with INPP5D/SHIP1. When phosphorylated at Tyr-1357, interacts with INPPL1/SHIP2. Interacts with RANBP9 and RANBP10, as well as SPSB1, SPSB2, SPSB3 and SPSB4. SPSB1 binding occurs in the presence and in the absence of HGF, however HGF treatment has a positive effect on this interaction. Interacts with MUC20; prevents interaction with GRB2 and suppresses hepatocyte growth factor-induced cell proliferation. Interacts with GRB10. Interacts with PTPN1 and PTPN2. Interacts with HSP90AA1 and HSP90AB1; the interaction suppresses MET kinase activity.
messages: In its inactive state, the C-terminal tail interacts with the catalytic domain and inhibits the kinase activity. Upon ligand binding, the C-terminal tail is displaced and becomes phosphorylated, thus increasing the kinase activity (By similarity).
messages: Membrane
messages: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells (By similarity).
messages: The beta-propeller Sema domain mediates binding to HGF.
messages: The kinase domain is involved in SPSB1 binding.
messages: Ubiquitinated. Ubiquitination by CBL regulates the receptor stability and activity through proteasomal degradation (By similarity).

9940:MOV10
gene id: 9940:MOV10
uniprot id: A0A6P3E6V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105601956
gene id: 9940:LOC105601956
uniprot id: B6CGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Secreted

9940:PFKFB1
gene id: 9940:PFKFB1
uniprot id: W5P7A7
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9940:TIPIN
gene id: 9940:TIPIN
uniprot id: W5Q9V8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

9940:POLA1
gene id: 9940:POLA1
uniprot id: W5Q828
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

9940:LOC101104526
gene id: 9940:LOC101104526
uniprot id: W5PNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PPP1R1C
gene id: 9940:PPP1R1C
uniprot id: W5Q5R3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9940:TIMP2
gene id: 9940:TIMP2
uniprot id: A0A6P9FRF3
uniprot id: C8BKC3
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IGFBP3
gene id: 9940:IGFBP3
uniprot id: C0LQH2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:LOC101110457
gene id: 9940:LOC101110457
uniprot id: A0A6P3EJI1
uniprot id: A0A836CTR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LZIC
gene id: 9940:LZIC
uniprot id: W5PA76
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9940:LOC101108434
gene id: 9940:LOC101108434
uniprot id: W5PJ38
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CDC42EP3
gene id: 9940:CDC42EP3
uniprot id: A0A6P3TE15
uniprot id: A0A6P7DWS2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113462
gene id: 9940:LOC101113462
uniprot id: W5PQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9940:TEF
gene id: 9940:TEF
uniprot id: A0A6P3YJS7
uniprot id: B6CM54
uniprot id: D7RFH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KNG1
gene id: 9940:KNG1
uniprot id: A0A6P3E6V8
uniprot id: W5QH45
uniprot id: W5QH46
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular space

9940:SERINC3
gene id: 9940:SERINC3
uniprot id: A0A6P3YL25
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAG2
gene id: 9940:RAG2
uniprot id: W5PL96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

9940:ATP2A2
gene id: 9940:ATP2A2
uniprot id: A0A6P3TGF4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INHBA
gene id: 9940:INHBA
uniprot id: P43032
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B. Activin A is a homodimer of beta-A. Activin B is a homodimer of beta-B. Activin AB is a dimer of beta-A and beta-B. Interacts with FST and FSTL3 (By similarity).
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9940:PDE7A
gene id: 9940:PDE7A
uniprot id: A0A6P3E905
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCMDC2
gene id: 9940:MCMDC2
uniprot id: A0A6P3YMZ9
uniprot id: W5Q932
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome

9940:ENTPD3
gene id: 9940:ENTPD3
uniprot id: A0A6P3T732
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9940:MTERF2
gene id: 9940:MTERF2
uniprot id: W5QAV5
names: Similarity
messages: Belongs to the mTERF family.

9940:ERAL1
gene id: 9940:ERAL1
uniprot id: A0A6P3EGZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP30
gene id: 9940:USP30
uniprot id: A0A6P3ENR6
uniprot id: W5Q6F3
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAPK1IP1L
gene id: 9940:MAPK1IP1L
uniprot id: W5QIV6
names: Similarity
messages: Belongs to the MISS family.

9940:LOC101110208
gene id: 9940:LOC101110208
uniprot id: W5P8Y1
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9940:LOC101103187
gene id: 9940:LOC101103187
uniprot id: W5PWI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

9940:LOC101114275
gene id: 9940:LOC101114275
uniprot id: A0A6P3YMK6
uniprot id: W5PTS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RRP15
gene id: 9940:RRP15
uniprot id: W5PPI2
names: Similarity
messages: Belongs to the RRP15 family.

9940:USE1
gene id: 9940:USE1
uniprot id: W5Q8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:LOC101116125
gene id: 9940:LOC101116125
uniprot id: A0A6P3EHD6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARHGAP19
gene id: 9940:ARHGAP19
uniprot id: A0A6P3EQX3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117745
gene id: 9940:LOC101117745
uniprot id: W5Q9X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PIAS3
gene id: 9940:PIAS3
uniprot id: A0A6P3THS1
names: Caution
names: Similarity
messages: Belongs to the PIAS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DYNLT2
gene id: 9940:DYNLT2
uniprot id: W5P4V1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9940:GTF3C3
gene id: 9940:GTF3C3
uniprot id: A0A6P3E1W5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSEN2
gene id: 9940:TSEN2
uniprot id: W5Q3J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.
messages: Nucleus

9940:LOC101119878
gene id: 9940:LOC101119878
uniprot id: W5PET1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9940:DCAF7
gene id: 9940:DCAF7
uniprot id: A0A6P3EIZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117413
gene id: 9940:LOC101117413
uniprot id: W5NTA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:NAGK
gene id: 9940:NAGK
uniprot id: W5PNZ1
names: Similarity
messages: Belongs to the eukaryotic-type N-acetylglucosamine kinase family.

9940:LOC101120653
gene id: 9940:LOC101120653
uniprot id: W5QGT2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:SCN3B
gene id: 9940:SCN3B
uniprot id: A0A6P3YMX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9940:PRL
gene id: 9940:PRL
uniprot id: P01240
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the somatotropin/prolactin family.
messages: Interacts with PRLR.
messages: Prolactin acts primarily on the mammary gland by promoting lactation, mammogenesis, mitogenesis and osmoregulation.
messages: Secreted

9940:GLDC
gene id: 9940:GLDC
uniprot id: A0A6P3E8A9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OGN
gene id: 9940:OGN
uniprot id: A0A6P3E7U7
uniprot id: W5PEL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:TXNDC16
gene id: 9940:TXNDC16
uniprot id: A0A835ZZS5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUMF2
gene id: 9940:SUMF2
uniprot id: W5PK71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9940:NUDT11
gene id: 9940:NUDT11
uniprot id: A0A835ZIW8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC15A1
gene id: 9940:SLC15A1
uniprot id: Q9BDH7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9940:NSG1
gene id: 9940:NSG1
uniprot id: A0A836D4S8
names: Caution
names: Similarity
messages: Belongs to the NSG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OST4
gene id: 9940:OST4
uniprot id: A0A6P3E2H0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113728
gene id: 9940:LOC101113728
uniprot id: A0A6P3TM89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel disulfide-linked heterodimer of an alpha chain and a beta chain. Self-associates and forms higher oligomers.
messages: Belongs to the clusterin family.
messages: Endoplasmic reticulum
messages: Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins.
messages: Membrane
messages: Microsome
messages: Mitochondrion membrane
messages: Nucleus
messages: Secreted
messages: chromaffin granule
messages: cytosol
messages: perinuclear region

9940:IFNAR2
gene id: 9940:IFNAR2
uniprot id: Q95207
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the type II cytokine receptor family.
messages: Cell membrane
messages: Expressed in the endometrium. Expressed in all tissues examined except conceptus at day 15 of pregnancy.
messages: Heterodimer with IFNAR1; forming the receptor for type I interferon. Interacts with the transcriptional factors STAT1 and STAT2. Interacts with JAK1. Interacts with USP18; indirectly via STAT2, it negatively regulates the assembly of the ternary interferon-IFNAR1-IFNAR2 complex and therefore type I interferon signaling.
messages: Phosphorylated on tyrosine residues upon interferon binding. Phosphorylation at Tyr-340 or Tyr-525 are sufficient to mediate interferon dependent activation of STAT1, STAT2 and STAT3 leading to antiproliferative effects on many different cell types (By similarity).
messages: Together with IFNAR1, forms the heterodimeric receptor for type I interferons (including interferons alpha, beta, epsilon, omega and kappa). Type I interferon binding activates the JAK-STAT signaling cascade, resulting in transcriptional activation or repression of interferon-regulated genes that encode the effectors of the interferon response. Mechanistically, type I interferon-binding brings the IFNAR1 and IFNAR2 subunits into close proximity with one another, driving their associated Janus kinases (JAKs) (TYK2 bound to IFNAR1 and JAK1 bound to IFNAR2) to cross-phosphorylate one another. The activated kinases phosphorylate specific tyrosine residues on the intracellular domains of IFNAR1 and IFNAR2, forming docking sites for the STAT transcription factors (STAT1, STAT2 and STAT). STAT proteins are then phosphorylated by the JAKs, promoting their translocation into the nucleus to regulate expression of interferon-regulated genes.

9940:AFF4
gene id: 9940:AFF4
uniprot id: A0A6P7E5T6
names: Similarity
messages: Belongs to the AF4 family.

9940:CHCHD1
gene id: 9940:CHCHD1
uniprot id: A0A6P3EGS2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117789
gene id: 9940:LOC101117789
uniprot id: W5PFG7
names: Similarity
messages: Belongs to the SERF family.

9940:NFKBIE
gene id: 9940:NFKBIE
uniprot id: A0A6P3EEU1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNAB2
gene id: 9940:KCNAB2
uniprot id: A0A6P3TLT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: axon
messages: cytoskeleton
messages: synaptosome

9940:LOC101113508
gene id: 9940:LOC101113508
uniprot id: W5PZ54
names: Similarity
messages: Belongs to the SCO1/2 family.

9940:EMP1
gene id: 9940:EMP1
uniprot id: W5QI16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9940:TMEM50A
gene id: 9940:TMEM50A
uniprot id: A0A6P3E264
uniprot id: A0A6P3E9C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP418
gene id: 9940:CFAP418
uniprot id: A0A6P3E977
uniprot id: W5P6M8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117971
gene id: 9940:LOC101117971
uniprot id: W5PXX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9940:KCNE1
gene id: 9940:KCNE1
uniprot id: A0A6P3E6C6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9940:GOSR2
gene id: 9940:GOSR2
uniprot id: W5PM29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

9940:CLDN17
gene id: 9940:CLDN17
uniprot id: A0A6P3TXE1
uniprot id: W5NSG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:MRPL47
gene id: 9940:MRPL47
uniprot id: A0A6P3DZU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119947
gene id: 9940:LOC101119947
uniprot id: A0A6P3EFK4
uniprot id: W5PSF4
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with RET in the pituitary gland; this interaction prevents the formation of the AIP-survivin complex.
messages: May play a positive role in AHR-mediated (aromatic hydrocarbon receptor) signaling, possibly by influencing its receptivity for ligand and/or its nuclear targeting.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPFIBP1
gene id: 9940:PPFIBP1
uniprot id: A0A836AAW7
names: Caution
names: Similarity
messages: Belongs to the liprin family. Liprin-beta subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DCTN1
gene id: 9940:DCTN1
uniprot id: W5PSJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

9940:SAP25
gene id: 9940:SAP25
uniprot id: A0A6P3T9Z5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DKC1
gene id: 9940:DKC1
uniprot id: B7TJ12
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9940:AP1G2
gene id: 9940:AP1G2
uniprot id: A0A6P3EFK7
uniprot id: W5QDA7
names: Caution
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDYN
gene id: 9940:PDYN
uniprot id: L7PA78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

9940:RAD52
gene id: 9940:RAD52
uniprot id: W5PSD3
names: Similarity
messages: Belongs to the RAD52 family.

9940:CNEP1R1
gene id: 9940:CNEP1R1
uniprot id: A0A6P3EFB9
uniprot id: W5Q6I9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAPPC2L
gene id: 9940:TRAPPC2L
uniprot id: A0A6P3YQC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:MMP13
gene id: 9940:MMP13
uniprot id: A0A6P9FRF2
uniprot id: C8BKE3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KBTBD2
gene id: 9940:KBTBD2
uniprot id: A0A836A7P0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC34A1
gene id: 9940:SLC34A1
uniprot id: O97704
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the SLC34A transporter family.
messages: Cell membrane
messages: Interacts via its C-terminal region with PDZK2. Interacts with SLC9A3R1.
messages: Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. The cotransport has a Na(+):Pi stoichiometry of 3:1 and is electrogenic.

9940:DDX59
gene id: 9940:DDX59
uniprot id: W5Q471
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

9940:AWAT2
gene id: 9940:AWAT2
uniprot id: A0A6P3ESV7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIF11
gene id: 9940:KIF11
uniprot id: A0A836CR49
uniprot id: W5NR75
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFI35
gene id: 9940:IFI35
uniprot id: W5P2S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9940:RPS14
gene id: 9940:RPS14
uniprot id: A0A6P3E642
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NT5DC1
gene id: 9940:NT5DC1
uniprot id: A0A836AC68
uniprot id: W5PI06
names: Caution
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBM28
gene id: 9940:RBM28
uniprot id: A0A836A7G5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NEIL2
gene id: 9940:NEIL2
uniprot id: A0A6P7DNS3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HDDC2
gene id: 9940:HDDC2
uniprot id: W5PDL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

9940:ELP4
gene id: 9940:ELP4
uniprot id: W5Q3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

9940:HOXC6
gene id: 9940:HOXC6
uniprot id: P49925
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9940:SLC7A6OS
gene id: 9940:SLC7A6OS
uniprot id: A0A836A5N3
uniprot id: W5NZM8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM168
gene id: 9940:TMEM168
uniprot id: W5NVP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

9940:PDE5A
gene id: 9940:PDE5A
uniprot id: A0A6P3E6K5
uniprot id: W5Q3B6
uniprot id: W5Q3B7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IGF2
gene id: 9940:IGF2
uniprot id: A0A6P7DAJ1
uniprot id: P10764
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Interacts with MYORG; this interaction is required for IGF2 secretion. Interacts with integrins ITGAV:ITGB3 and ITGA6:ITGB4; integrin-binding is required for IGF2 signaling.
messages: Preptin undergoes glucose-mediated co-secretion with insulin, and acts as physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3.
messages: Proteolytically processed by PCSK4, proIGF2 is cleaved at Arg-128 and Arg-92 to generate big-IGF2 and mature IGF2.
messages: Secreted
messages: The IGF2 locus is imprinted. Paternal inherited gene is expressed, while the maternal inherited gene is imprinted, hence silenced.
messages: The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate (By similarity).
messages: The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver. Acts as a ligand for integrin which is required for IGF2 signaling. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate.

9940:CX3CR1
gene id: 9940:CX3CR1
uniprot id: A0A6P3EC29
uniprot id: W5PX52
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Found in a ternary complex with CX3CL1 and ITGAV:ITGB3 or ITGA4:ITGB1.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FANCG
gene id: 9940:FANCG
uniprot id: A0A836AJ36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LSM1
gene id: 9940:LSM1
uniprot id: A0A6P3ES80
uniprot id: W5NT81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: Interacts with SLBP; interaction with SLBP occurs when histone mRNA is being rapidly degraded during the S phase. LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DLL4
gene id: 9940:DLL4
uniprot id: W5QGG2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9940:AR
gene id: 9940:AR
uniprot id: S5U7M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9940:SS18L2
gene id: 9940:SS18L2
uniprot id: A0A6P9FQF5
uniprot id: B9VH03
names: Caution
names: Similarity
messages: Belongs to the SS18 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMIM13
gene id: 9940:SMIM13
uniprot id: A0A6P3YS55
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDR33
gene id: 9940:WDR33
uniprot id: A0A6P3E9I0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FIBIN
gene id: 9940:FIBIN
uniprot id: A0A6P3EGP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FIBIN family.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer; disulfide-linked. Seems to also exist as monomers.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KEF53 p03
gene id: 9940:KEF53_p03
uniprot id: A0A0E3JPI4
uniprot id: O78756
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9940:NXNL2
gene id: 9940:NXNL2
uniprot id: A0A6P3YFR1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAFD1
gene id: 9940:TRAFD1
uniprot id: A0A6P3EHX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP1B1
gene id: 9940:ATP1B1
uniprot id: A0A6P7EJR7
uniprot id: P05028
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Glutathionylated (By similarity). N-glycosylated (By similarity).
messages: Involved in cell adhesion and establishing epithelial cell polarity.
messages: Membrane
messages: The C-terminal lobe folds into an immunoglobulin-like domain and mediates cell adhesion properties.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit. Interacts with catalytic subunit ATP12A (By similarity). Interacts with regulatory subunit FXYD1 (By similarity). Interacts with regulatory subunit FXYD3 (By similarity). Interacts with NKAIN1, NKAIN2 and NKAIN4 (By similarity). Interacts with MLC1. Part of a complex containing MLC1, TRPV4, AQP4 and HEPACAM. Interacts with KIRREL3 (By similarity). Interacts with OBSCN (via protein kinase domain 1) (By similarity). Interacts with TRAF3 and TRAF6 (By similarity).
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. Plays a role in innate immunity by enhancing virus-triggered induction of interferons (IFNs) and interferon stimulated genes (ISGs). Mechanistically, enhances the ubiquitination of TRAF3 and TRAF6 as well as the phosphorylation of TAK1 and TBK1.
messages: sarcolemma

9940:UFC1
gene id: 9940:UFC1
uniprot id: W5PIN1
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

9940:GPATCH11
gene id: 9940:GPATCH11
uniprot id: W5PJD9
names: Similarity
messages: Belongs to the GPATCH11 family.

9940:MAPK9
gene id: 9940:MAPK9
uniprot id: A0A836A537
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADCYAP1
gene id: 9940:ADCYAP1
uniprot id: P16613
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucagon family.
messages: Binding to its receptor activates G proteins and stimulates adenylate cyclase in pituitary cells (By similarity). Promotes neuron projection development through the RAPGEF2/Rap1/B-Raf/ERK pathway (By similarity). In chromaffin cells, induces long-lasting increase of intracellular calcium concentrations and neuroendocrine secretion (By similarity). Involved in the control of glucose homeostasis, induces insulin secretion by pancreatic beta cells (By similarity).
messages: Interacts with ADCYAP1R1 (via N-terminal extracellular domain).
messages: Secreted

9940:KCNV2
gene id: 9940:KCNV2
uniprot id: W5PUZ4
names: Subcellular Location Annotation
messages: Membrane

9940:MPV17
gene id: 9940:MPV17
uniprot id: A0A836D761
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FEV
gene id: 9940:FEV
uniprot id: A0A6P3EA45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CACNG3
gene id: 9940:CACNG3
uniprot id: W5Q8C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

9940:FXYD5
gene id: 9940:FXYD5
uniprot id: W5P3Q2
names: Similarity
messages: Belongs to the FXYD family.

9940:NDUFB8
gene id: 9940:NDUFB8
uniprot id: D5M8S1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9940:CAV3
gene id: 9940:CAV3
uniprot id: A0A6P3EN41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: caveola
messages: sarcolemma

9940:FBXL4
gene id: 9940:FBXL4
uniprot id: A0A6P3TGE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RABL3
gene id: 9940:RABL3
uniprot id: A0A6P3DZM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116799
gene id: 9940:LOC101116799
uniprot id: W5PHS2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9940:LOC101119456
gene id: 9940:LOC101119456
uniprot id: W5Q4D7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9940:ASZ1
gene id: 9940:ASZ1
uniprot id: Q09YI3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation (By similarity).

9940:MC1R
gene id: 9940:MC1R
uniprot id: A0A835ZSD6
uniprot id: E4WMB4
uniprot id: O19037
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MGRN1, but does not undergo MGRN1-mediated ubiquitination; this interaction competes with GNAS-binding and thus inhibits agonist-induced cAMP production. Interacts with OPN3; the interaction results in a decrease in MC1R-mediated cAMP signaling and ultimately a decrease in melanin production in melanocytes.
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Mediates melanogenesis, the production of eumelanin (black/brown) and phaeomelanin (red/yellow), via regulation of cAMP signaling in melanocytes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDIPT
gene id: 9940:CDIPT
uniprot id: A0A6P3EQV3
uniprot id: W5P5G0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:P3H1
gene id: 9940:P3H1
uniprot id: A0A6P3TIG0
uniprot id: W5QGX4
names: Caution
names: Similarity
messages: Belongs to the leprecan family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYL4
gene id: 9940:MYL4
uniprot id: A0A6P3TLA0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IDH1
gene id: 9940:IDH1
uniprot id: Q6XUZ5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-374 dramatically reduces catalytic activity.
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (By similarity). Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (By similarity). May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity).
messages: Homodimer.
messages: cytosol

9940:LOC101106373
gene id: 9940:LOC101106373
uniprot id: A0A6P3ENW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NSF
gene id: 9940:NSF
uniprot id: W5PMS2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

9940:BAG5
gene id: 9940:BAG5
uniprot id: A0A836CUU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MDM1
gene id: 9940:MDM1
uniprot id: W5NTA6
uniprot id: W5NTA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM1 family.
messages: Nucleus
messages: centriole

9940:TMEM170B
gene id: 9940:TMEM170B
uniprot id: W5PZF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM170 family.
messages: Membrane

9940:ORC2
gene id: 9940:ORC2
uniprot id: W5Q5B2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9940:GSDME
gene id: 9940:GSDME
uniprot id: W5PM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9940:MRPL10
gene id: 9940:MRPL10
uniprot id: A0A6P3EA93
uniprot id: W5PDX6
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFTPC
gene id: 9940:SFTPC
uniprot id: A0A6P3CWK6
uniprot id: Q9N276
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: surface film

9940:CERS6
gene id: 9940:CERS6
uniprot id: A0A6P3E8M1
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ST6GALNAC6
gene id: 9940:ST6GALNAC6
uniprot id: A0A836AIM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120875
gene id: 9940:LOC101120875
uniprot id: W5Q1G8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9940:SAT2
gene id: 9940:SAT2
uniprot id: A0A6P3EA18
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AVP
gene id: 9940:AVP
uniprot id: B2KPN5
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

9940:ADAMTS6
gene id: 9940:ADAMTS6
uniprot id: A0A835ZYN8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:LOC101106489
gene id: 9940:LOC101106489
uniprot id: A0A6P3TT55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:MYO1A
gene id: 9940:MYO1A
uniprot id: W5PD30
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9940:RNPC3
gene id: 9940:RNPC3
uniprot id: A0A6P3E6S0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Found in a complex with m(7)G-capped U12 snRNA. Interacts with PDCD7.
messages: Nucleus
messages: Participates in pre-mRNA U12-dependent splicing, performed by the minor spliceosome which removes U12-type introns. U12-type introns comprises less than 1% of all non-coding sequences. Binds to the 3'-stem-loop of m(7)G-capped U12 snRNA.

9940:LOC101111396
gene id: 9940:LOC101111396
uniprot id: A0A6P3EM04
uniprot id: W5PJZ5
names: Caution
names: Similarity
messages: Belongs to the HHIP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GCM2
gene id: 9940:GCM2
uniprot id: A0A6P3EP40
uniprot id: W5Q1Q9
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TDRD7
gene id: 9940:TDRD7
uniprot id: W5PNS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TDRD7 family.
messages: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
messages: Cytoplasm
messages: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1.

9940:NUDT19
gene id: 9940:NUDT19
uniprot id: W5P254
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9940:LOC101118481
gene id: 9940:LOC101118481
uniprot id: A0A836ADJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMC1B
gene id: 9940:SMC1B
uniprot id: A0A6P3TFJ5
uniprot id: W5QDN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERCC8
gene id: 9940:ERCC8
uniprot id: A0A6P3EN99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB9A
gene id: 9940:RAB9A
uniprot id: C5IJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

9940:MLN
gene id: 9940:MLN
uniprot id: O18845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Plays an important role in the regulation of interdigestive gastrointestinal motility and indirectly causes rhythmic contraction of duodenal and colonic smooth muscle.
messages: Secreted

9940:LOC101116286
gene id: 9940:LOC101116286
uniprot id: W5QFL1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9940:CHAC2
gene id: 9940:CHAC2
uniprot id: W5P231
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family. ChaC subfamily.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

9940:CD40
gene id: 9940:CD40
uniprot id: A0A6P3EKT3
uniprot id: W5PEW0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C5H5orf63
gene id: 9940:C5H5orf63
uniprot id: A0A836D1U4
names: Caution
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NRSN2
gene id: 9940:NRSN2
uniprot id: A0A836CXZ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CIPC
gene id: 9940:CIPC
uniprot id: A0A6P3CWZ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFT27
gene id: 9940:IFT27
uniprot id: A0A6P3CWV2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOS3
gene id: 9940:NOS3
uniprot id: Q4U3W6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

9940:STIM1
gene id: 9940:STIM1
uniprot id: W5NU73
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:ETFDH
gene id: 9940:ETFDH
uniprot id: A0A835ZPU0
uniprot id: W5P1M1
names: Caution
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MPST
gene id: 9940:MPST
uniprot id: A0A836D855
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DSTN
gene id: 9940:DSTN
uniprot id: A0A6P3YPG0
names: Caution
names: Function
names: Similarity
messages: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
messages: Belongs to the actin-binding proteins ADF family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RRAGC
gene id: 9940:RRAGC
uniprot id: C5IJ90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9940:ORMDL1
gene id: 9940:ORMDL1
uniprot id: A0A6P3E1H8
uniprot id: A0A6P3E9I6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LYZ
gene id: 9940:LYZ
uniprot id: A4Z8Q3
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9940:CYP2D6
gene id: 9940:CYP2D6
uniprot id: F1CGV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:MED6
gene id: 9940:MED6
uniprot id: W5QJ79
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

9940:SH3BGRL
gene id: 9940:SH3BGRL
uniprot id: A0A6P3EN38
names: Caution
names: Similarity
messages: Belongs to the SH3BGR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DIRAS2
gene id: 9940:DIRAS2
uniprot id: A0A6P3E8U7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119509
gene id: 9940:LOC101119509
uniprot id: W5Q124
names: Similarity
messages: Belongs to the serpin family.

9940:MID1IP1
gene id: 9940:MID1IP1
uniprot id: A0A6P3ESB0
uniprot id: A0A6P3TAS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PATJ
gene id: 9940:PATJ
uniprot id: W5PGV1
names: Subcellular Location Annotation
messages: Cell membrane
messages: tight junction

9940:SST
gene id: 9940:SST
uniprot id: A0A6P7DSS5
uniprot id: O46688
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: C-terminal amidation of the neuronostatin peptide is required for its biological activity, including for the regulation of mean arterial pressure.
messages: Inhibits the secretion of pituitary hormones, including that of growth hormone/somatotropin (GH1), PRL, ACTH, luteinizing hormone (LH) and TSH. Also impairs ghrelin- and GnRH-stimulated secretion of GH1 and LH; the inhibition of ghrelin-stimulated secretion of GH1 can be further increased by neuronostatin.
messages: May enhance low-glucose-induced glucagon release by pancreatic alpha cells. This effect may be mediated by binding to GPR107 and PKA activation (By similarity). May regulate cardiac contractile function (By similarity). May compromise cardiomyocyte viability. In the central nervous system, may impair memory retention and may affect hippocampal excitability. May also have anxiolytic and anorexigenic effects. May play a role in arterial pressure regulation (By similarity). May inhibit basal, but not ghrelin- or GnRH-stimulated secretion of GH1 or LH, but does not affect the release of other pituitary hormones, including PRL, ACTH, FSH or TSH. Potentiates inhibitory action of somatostatin on ghrelin-stimulated secretion of GH1, but not that on GnRH-stimulated secretion of LH (By similarity).
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STRN
gene id: 9940:STRN
uniprot id: A0A6P3E7C7
uniprot id: W5PK29
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C25H1orf131
gene id: 9940:C25H1orf131
uniprot id: A0A835ZHB5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF410
gene id: 9940:ZNF410
uniprot id: A0A836ADQ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPA2
gene id: 9940:HSPA2
uniprot id: A0A6P3EBB6
uniprot id: W5NSB0
names: Caution
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAF4B
gene id: 9940:TAF4B
uniprot id: A0A6P3EDV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OXSM
gene id: 9940:OXSM
uniprot id: W5P1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

9940:ERP44
gene id: 9940:ERP44
uniprot id: A0A6P3E5U3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJB14
gene id: 9940:DNAJB14
uniprot id: A0A6P3EA85
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PARP12
gene id: 9940:PARP12
uniprot id: A0A6P3TN32
uniprot id: W5PS68
names: Caution
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLDIP3
gene id: 9940:POLDIP3
uniprot id: A0A6P3E3M9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114847
gene id: 9940:LOC101114847
uniprot id: W5P834
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9940:AP3M1
gene id: 9940:AP3M1
uniprot id: W5PFM2
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9940:CAVIN4
gene id: 9940:CAVIN4
uniprot id: W5PCH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

9940:TPD52
gene id: 9940:TPD52
uniprot id: W5PEN2
names: Similarity
messages: Belongs to the TPD52 family.

9940:TBC1D25
gene id: 9940:TBC1D25
uniprot id: A0A6P3EF14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104426
gene id: 9940:LOC101104426
uniprot id: A0A6P3EL46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GUCA2B
gene id: 9940:GUCA2B
uniprot id: A0A6P3E4W2
uniprot id: W5QGN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD2BP2
gene id: 9940:CD2BP2
uniprot id: A0A836CRS4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GNPAT
gene id: 9940:GNPAT
uniprot id: W5NZ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Peroxisome membrane

9940:HSD17B7
gene id: 9940:HSD17B7
uniprot id: W5PMQ4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

9940:LOC101121936
gene id: 9940:LOC101121936
uniprot id: A0A6P3EDG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SRD5A3
gene id: 9940:SRD5A3
uniprot id: A0A836AAR3
uniprot id: W5NTG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT).
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KEF53 p11
gene id: 9940:KEF53_p11
uniprot id: O78749
uniprot id: Q5MA75
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 2 heme A groups non-covalently per subunit.
messages: Binds a copper B center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome (By similarity). The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (PubMed:27654913). As a newly synthesized protein, rapidly incorporates into a multi-subunit assembly intermediate in the inner membrane, called MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase) complex, whose core components are COA3/MITRAC12 and COX14. Within the MITRAC complex, interacts with COA3 and with SMIM20/MITRAC7; the interaction with SMIM20 stabilizes the newly synthesized MT-CO1 and prevents its premature turnover. Interacts with TMEM177 in a COX20-dependent manner (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9940:MFSD8
gene id: 9940:MFSD8
uniprot id: A0A836A1M8
uniprot id: W5Q200
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF214
gene id: 9940:ZNF214
uniprot id: A0A835ZZS8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AMIGO1
gene id: 9940:AMIGO1
uniprot id: A0A6P3DZ84
uniprot id: W5PP59
names: Caution
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM106A
gene id: 9940:TMEM106A
uniprot id: A0A836A0T2
uniprot id: W5P5F0
names: Caution
names: Similarity
messages: Belongs to the TMEM106 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM72A
gene id: 9940:FAM72A
uniprot id: A0A6P3EJC6
uniprot id: W5P4X7
names: Caution
names: Similarity
messages: Belongs to the FAM72 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DKK2
gene id: 9940:DKK2
uniprot id: W5PGQ6
names: Similarity
messages: Belongs to the dickkopf family.

9940:CES5A
gene id: 9940:CES5A
uniprot id: A0A835ZSH4
uniprot id: W5QB42
names: Caution
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SRXN1
gene id: 9940:SRXN1
uniprot id: A0A6P3E992
names: Caution
names: Similarity
messages: Belongs to the sulfiredoxin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBRG4
gene id: 9940:TBRG4
uniprot id: A0A6P3E460
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DUS4L
gene id: 9940:DUS4L
uniprot id: A0A836D3L8
names: Caution
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DUSP3
gene id: 9940:DUSP3
uniprot id: A0A6P3YNT6
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRAMD2B
gene id: 9940:GRAMD2B
uniprot id: A0A836AG87
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SOCS4
gene id: 9940:SOCS4
uniprot id: A0A6P3E6B0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAD51C
gene id: 9940:RAD51C
uniprot id: A0A6P3EDV6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GCSH
gene id: 9940:GCSH
uniprot id: A0A836CV94
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUP205
gene id: 9940:NUP205
uniprot id: W5PH42
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

9940:CPB2
gene id: 9940:CPB2
uniprot id: A0A6P3EGI2
uniprot id: W5PD62
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJC27
gene id: 9940:DNAJC27
uniprot id: A0A836A8Q9
names: Caution
names: Function
names: Subunit
messages: GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling.
messages: Interacts directly with MAPK1 (wild-type and kinase-deficient forms). Interacts directly (in GTP-bound form) with MAP2K1 (wild-type and kinase-deficient forms).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ESCO2
gene id: 9940:ESCO2
uniprot id: W5PZN9
names: Subcellular Location Annotation
messages: Nucleus

9940:RAB23
gene id: 9940:RAB23
uniprot id: A0A6P7D7U2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDF5
gene id: 9940:GDF5
uniprot id: W5PSD6
names: Similarity
messages: Belongs to the TGF-beta family.

9940:LOC101104213
gene id: 9940:LOC101104213
uniprot id: A0A835ZEW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122633
gene id: 9940:LOC101122633
uniprot id: A0A835ZNK7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACKR1
gene id: 9940:ACKR1
uniprot id: W5PCT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Has a promiscuous chemokine-binding profile, interacting with inflammatory chemokines of both the CXC and the CC subfamilies but not with homeostatic chemokines. Acts as a receptor for chemokines including CCL2, CCL5, CCL7, CCL11, CCL13, CCL14, CCL17, CXCL5, CXCL6, IL8/CXCL8, CXCL11, GRO, RANTES, MCP-1 and TARC. May regulate chemokine bioavailability and, consequently, leukocyte recruitment through two distinct mechanisms: when expressed in endothelial cells, it sustains the abluminal to luminal transcytosis of tissue-derived chemokines and their subsequent presentation to circulating leukocytes; when expressed in erythrocytes, serves as blood reservoir of cognate chemokines but also as a chemokine sink, buffering potential surges in plasma chemokine levels.
messages: Belongs to the G-protein coupled receptor 1 family. Atypical chemokine receptor subfamily.
messages: Early endosome
messages: Membrane
messages: Recycling endosome

9940:LOC101113195
gene id: 9940:LOC101113195
uniprot id: A0A6P3TGQ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPS15
gene id: 9940:MRPS15
uniprot id: A0A6P3E3S3
uniprot id: W5QEM0
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRM3
gene id: 9940:GRM3
uniprot id: W5PZV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

9940:CLEC1A
gene id: 9940:CLEC1A
uniprot id: A0A6P3ECD1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HLCS
gene id: 9940:HLCS
uniprot id: W5PXH8
names: Similarity
messages: Belongs to the biotin--protein ligase family.

9940:LOC443441
gene id: 9940:LOC443441
uniprot id: Q29422
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
messages: Cell membrane
messages: During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes, before trafficking back to the cell surface. Interaction with saposin C is required for the loading of bacterial lipid antigens onto CD1B in the lysosome (By similarity).
messages: Endosome membrane
messages: Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C (By similarity).
messages: Lysosome membrane

9940:MTX2
gene id: 9940:MTX2
uniprot id: W5Q7N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9940:ARHGAP26
gene id: 9940:ARHGAP26
uniprot id: A0A6P3E9P1
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton
messages: focal adhesion

9940:RFXANK
gene id: 9940:RFXANK
uniprot id: A0A6P3EDG0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKACB
gene id: 9940:PRKACB
uniprot id: W5PWH9
uniprot id: W5PWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Nucleus

9940:ARGLU1
gene id: 9940:ARGLU1
uniprot id: A0A6P3ECQ7
names: Caution
names: Similarity
messages: Belongs to the UPF0430 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLHL15
gene id: 9940:KLHL15
uniprot id: A0A6P3EMQ9
names: Subcellular Location Annotation
messages: Nucleus

9940:DPT
gene id: 9940:DPT
uniprot id: A0A6P3EJK4
uniprot id: W5PHI8
names: Caution
names: Similarity
messages: Belongs to the dermatopontin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LYPLA1
gene id: 9940:LYPLA1
uniprot id: A0A6P3CY59
uniprot id: A0A6P7E7Q5
names: Caution
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IDNK
gene id: 9940:IDNK
uniprot id: A0A6P3YJ61
names: Caution
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HPS3
gene id: 9940:HPS3
uniprot id: W5P4Y4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

9940:BBS2
gene id: 9940:BBS2
uniprot id: W5QAJ5
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

9940:MYO1E
gene id: 9940:MYO1E
uniprot id: A0A6P3E681
uniprot id: W5QI40
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOC4L
gene id: 9940:NOC4L
uniprot id: A0A836CV17
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Nucleus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL1R1
gene id: 9940:IL1R1
uniprot id: W5PUF0
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9940:TCTN3
gene id: 9940:TCTN3
uniprot id: W5P952
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

9940:CGRRF1
gene id: 9940:CGRRF1
uniprot id: A0A6P3E7W2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNIH1
gene id: 9940:CNIH1
uniprot id: W5QIU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9940:HTR2B
gene id: 9940:HTR2B
uniprot id: W5QHN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts (via C-terminus) with MPDZ.
messages: Membrane
messages: synaptosome

9940:ODR4
gene id: 9940:ODR4
uniprot id: W5PBQ8
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

9940:TRUB2
gene id: 9940:TRUB2
uniprot id: A0A6P3E8H5
uniprot id: W5PLM8
names: Caution
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RECQL
gene id: 9940:RECQL
uniprot id: A0A6P3E868
uniprot id: W5QGJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TCP1
gene id: 9940:TCP1
uniprot id: A0A6P3EH93
names: Caution
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNF4A
gene id: 9940:HNF4A
uniprot id: F1CGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9940:CALCA
gene id: 9940:CALCA
uniprot id: W5P7Y6
names: Similarity
messages: Belongs to the calcitonin family.

9940:RPL10L
gene id: 9940:RPL10L
uniprot id: W5NRP9
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9940:BSP5L
gene id: 9940:BSP5L
uniprot id: A0A6P3CX92
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:APH1B
gene id: 9940:APH1B
uniprot id: A0A6P3TP54
uniprot id: W5QHZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HTATSF1
gene id: 9940:HTATSF1
uniprot id: W5PNJ4
names: Similarity
messages: Belongs to the HTATSF1 family.

9940:GPR107
gene id: 9940:GPR107
uniprot id: W5PE43
names: Subcellular Location Annotation
messages: Membrane

9940:LRIF1
gene id: 9940:LRIF1
uniprot id: A0A6P3TSB5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FADS1
gene id: 9940:FADS1
uniprot id: A0A6P3ED97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CACNG2
gene id: 9940:CACNG2
uniprot id: W5QCC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

9940:SPP1
gene id: 9940:SPP1
uniprot id: Q9XSY9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity.
messages: Belongs to the osteopontin family.
messages: Extensively phosphorylated by FAM20C in the extracellular medium at multiple sites within the S-x-E/pS motif (By similarity). The phosphorylated form inhibits hydroxyapatite crystallization. Dephosphorylation via a mechanism involving ALPL/TNAP promotes hydroxyapatite crystallization (By similarity).
messages: Forms covalent cross-links mediated by transglutaminase TGM2, between a glutamine and the epsilon-amino group of a lysine residue, forming homopolymers and heteropolymers, increasing its collagen binding properties.
messages: Ligand for integrin alpha-V/beta-3.
messages: Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction.
messages: O-glycosylated.
messages: Secreted

9940:AP1S1
gene id: 9940:AP1S1
uniprot id: A0A6P3YPG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: clathrin-coated pit

9940:NSUN7
gene id: 9940:NSUN7
uniprot id: A0A6P3E6U7
uniprot id: A0A6P7E958
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INSR
gene id: 9940:INSR
uniprot id: A0A6P3EDM5
uniprot id: W5NQ38
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GNB4
gene id: 9940:GNB4
uniprot id: A0A6P3E534
uniprot id: W5QHP5
names: Caution
names: Similarity
messages: Belongs to the WD repeat G protein beta family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB27A
gene id: 9940:RAB27A
uniprot id: C0IZ95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9940:TRMT1L
gene id: 9940:TRMT1L
uniprot id: W5P0U7
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

9940:RTN4
gene id: 9940:RTN4
uniprot id: B9VGZ5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:MSC
gene id: 9940:MSC
uniprot id: A0A6P3E921
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF24
gene id: 9940:ZNF24
uniprot id: W5P6P7
names: Subcellular Location Annotation
messages: Nucleus

9940:BMI1
gene id: 9940:BMI1
uniprot id: A0A6P7EM60
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FDFT1
gene id: 9940:FDFT1
uniprot id: A0A6P3E118
uniprot id: W5Q0X2
names: Caution
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RASSF1
gene id: 9940:RASSF1
uniprot id: C5IJA2
names: Subcellular Location Annotation
messages: cytoskeleton

9940:SH3GLB1
gene id: 9940:SH3GLB1
uniprot id: A0A6P3E6M8
uniprot id: W5PZR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Midbody
messages: Mitochondrion outer membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: autophagosome membrane

9940:LOC105613870
gene id: 9940:LOC105613870
uniprot id: W5NTP5
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:SRSF7
gene id: 9940:SRSF7
uniprot id: A0A6P3EB34
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD11
gene id: 9940:PSMD11
uniprot id: A0A6P3YL05
names: Caution
names: Similarity
messages: Belongs to the proteasome subunit S9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NMBR
gene id: 9940:NMBR
uniprot id: A0A836A887
uniprot id: W5NT48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:REPS1
gene id: 9940:REPS1
uniprot id: A0A6P3TJK6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCRL2
gene id: 9940:CCRL2
uniprot id: A0A6P3EEN4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC117
gene id: 9940:CCDC117
uniprot id: A0A6P3EHZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ORC3
gene id: 9940:ORC3
uniprot id: A0A6P3TRK6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

9940:HIKESHI
gene id: 9940:HIKESHI
uniprot id: A0A6P3EJV5
uniprot id: W5P2Q7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:GMFB
gene id: 9940:GMFB
uniprot id: W5QIU5
names: Similarity
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.

9940:MRAS
gene id: 9940:MRAS
uniprot id: A0A836A1J5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110727
gene id: 9940:LOC101110727
uniprot id: W5Q9K7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:TMED6
gene id: 9940:TMED6
uniprot id: W5P042
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:PEF1
gene id: 9940:PEF1
uniprot id: A0A836ABW7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAPSS1
gene id: 9940:PAPSS1
uniprot id: A0A6P3EDP0
names: Caution
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC13A1
gene id: 9940:SLC13A1
uniprot id: W5NQJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9940:AURKAIP1
gene id: 9940:AURKAIP1
uniprot id: A0A6P3E8R8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UHRF2
gene id: 9940:UHRF2
uniprot id: A0A6P3E1C3
uniprot id: W5PW10
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LTV1
gene id: 9940:LTV1
uniprot id: W5NUC1
names: Similarity
messages: Belongs to the LTV1 family.

9940:CDC25B
gene id: 9940:CDC25B
uniprot id: W5NT36
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9940:IGF1
gene id: 9940:IGF1
uniprot id: A0A3S5HYL2
uniprot id: A0A836D4F5
uniprot id: A0FJ28
uniprot id: P10763
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Forms a ternary complex with IGFR1 and ITGAV:ITGB3. Forms a ternary complex with IGFR1 and ITGA6:ITGB4.
messages: Secreted
messages: The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exocytosis of IGF1 is required for sensory perception of smell in the olfactory bulb. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins ITGAV:ITGB3 and ITGA6:ITGB4. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling. Induces the phosphorylation and activation of IGFR1, MAPK3/ERK1, MAPK1/ERK2 and AKT1 (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIT
gene id: 9940:KIT
uniprot id: X2BZP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9940:LOC101110758
gene id: 9940:LOC101110758
uniprot id: A0A6P7D1J1
uniprot id: Q6Q311
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP2R5A
gene id: 9940:PPP2R5A
uniprot id: A0A6P3EIC9
uniprot id: W5PM65
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLPS
gene id: 9940:CLPS
uniprot id: A0A6P3EJ04
uniprot id: W5PS75
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NEUROD6
gene id: 9940:NEUROD6
uniprot id: A0A6P3EBY5
uniprot id: W5PF29
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITIH2
gene id: 9940:ITIH2
uniprot id: W5PW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9940:CANX
gene id: 9940:CANX
uniprot id: A0A6P3YHQ8
uniprot id: W5NYZ5
names: Caution
names: Similarity
messages: Belongs to the calreticulin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102231
gene id: 9940:LOC101102231
uniprot id: W5NTP1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:SLCO2A1
gene id: 9940:SLCO2A1
uniprot id: Q2VLH9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:KCTD9
gene id: 9940:KCTD9
uniprot id: A0A6P3E7Z2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RESP18
gene id: 9940:RESP18
uniprot id: A0A6P3E1S0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPFFR2
gene id: 9940:NPFFR2
uniprot id: V5JGC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9940:OPRM1
gene id: 9940:OPRM1
uniprot id: W5P1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

9940:SNAP47
gene id: 9940:SNAP47
uniprot id: W5PA99
names: Similarity
messages: Belongs to the SVAP1 family.

9940:PPP1R3D
gene id: 9940:PPP1R3D
uniprot id: A0A6P3EIU3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITPKC
gene id: 9940:ITPKC
uniprot id: W5PAI2
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9940:LOC101122931
gene id: 9940:LOC101122931
uniprot id: W5QB92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PCBD1
gene id: 9940:PCBD1
uniprot id: A0A6P3YPQ5
names: Caution
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A19
gene id: 9940:SLC25A19
uniprot id: B7U169
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:METAP2
gene id: 9940:METAP2
uniprot id: A0A6P3EBF7
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM126A
gene id: 9940:TMEM126A
uniprot id: A0A6P3EF95
uniprot id: A0A836CSQ4
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPIA
gene id: 9940:PPIA
uniprot id: K4P1S5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9940:HMGXB4
gene id: 9940:HMGXB4
uniprot id: A0A836A8I9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GALNT1
gene id: 9940:GALNT1
uniprot id: A0A6P3T9B5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL28
gene id: 9940:RPL28
uniprot id: W5NTJ6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL28 family.

9940:CDKN1A
gene id: 9940:CDKN1A
uniprot id: A0A6P3CWX5
uniprot id: A0A6P3TED5
names: Caution
names: Similarity
messages: Belongs to the CDI family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPLOC4
gene id: 9940:NPLOC4
uniprot id: A0A6P3YP68
names: Caution
names: Similarity
messages: Belongs to the NPL4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IMMP1L
gene id: 9940:IMMP1L
uniprot id: A0A6P3T5E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

9940:MSL2
gene id: 9940:MSL2
uniprot id: A0A6P3E780
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:B4GALT1
gene id: 9940:B4GALT1
uniprot id: A0A6P9FQT2
uniprot id: F5CC79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTR2
gene id: 9940:ACTR2
uniprot id: A0A6P3YGL4
names: Similarity
messages: Belongs to the actin family.

9940:F13B
gene id: 9940:F13B
uniprot id: W5PXX3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:HSF2
gene id: 9940:HSF2
uniprot id: A0A6P3E8D2
uniprot id: W5PEL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BAP1
gene id: 9940:BAP1
uniprot id: W5P3U3
names: Similarity
messages: Belongs to the peptidase C12 family.

9940:LOC101123247
gene id: 9940:LOC101123247
uniprot id: A0A6P3E684
uniprot id: W5NVV5
names: Caution
names: Similarity
messages: Belongs to the PI3K p85 subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ASB5
gene id: 9940:ASB5
uniprot id: A0A6P3EGW7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117117
gene id: 9940:LOC101117117
uniprot id: A0A6P3EJB6
uniprot id: A0A6P3TI07
names: Caution
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD93
gene id: 9940:CD93
uniprot id: C5ISB5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:B3GNT7
gene id: 9940:B3GNT7
uniprot id: W5QHQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9940:NXPE3
gene id: 9940:NXPE3
uniprot id: A0A6P3TV58
names: Similarity
messages: Belongs to the NXPE family.

9940:LCK
gene id: 9940:LCK
uniprot id: B7U173
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9940:LOC101111593
gene id: 9940:LOC101111593
uniprot id: A0A6P3E6F9
uniprot id: W5Q0C6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-APP binds TNFRSF21 triggering caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6).
messages: Nucleus
messages: Perikaryon
messages: Secreted
messages: The gamma-CTF peptides as well as the caspase-cleaved peptides, including C31, are potent enhancers of neuronal apoptosis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle
messages: clathrin-coated pit
messages: growth cone

9940:SNRPD1
gene id: 9940:SNRPD1
uniprot id: A0A6P3EL45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP core protein family.
messages: Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Most spliceosomal snRNPs contain a common set of Sm proteins, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. Component of the U1 snRNP. The U1 snRNP is composed of the U1 snRNA and the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG, and at least three U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. Component of the U4/U6-U5 tri-snRNP complex composed of the U4, U6 and U5 snRNAs and at least PRPF3, PRPF4, PRPF6, PRPF8, PRPF31, SNRNP200, TXNL4A, SNRNP40, SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, DDX23, CD2BP2, PPIH, SNU13, EFTUD2, SART1 and USP39, plus LSM2, LSM3, LSM4, LSM5, LSM6, LSM7 and LSM8. Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Part of the SMN-Sm complex that contains SMN1, GEMIN2/SIP1, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8, STRAP/UNRIP and the Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG; catalyzes core snRNPs assembly. Forms a 6S pICln-Sm complex composed of CLNS1A/pICln, SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG; ring-like structure where CLNS1A/pICln mimics additional Sm proteins and which is unable to assemble into the core snRNP.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:ARMC9
gene id: 9940:ARMC9
uniprot id: W5QHP2
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

9940:OLFML1
gene id: 9940:OLFML1
uniprot id: W5Q3G8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LOC101113745
gene id: 9940:LOC101113745
uniprot id: A0A6P3EBX7
uniprot id: W5PN13
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM198 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MED21
gene id: 9940:MED21
uniprot id: A0A836D872
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC1A3
gene id: 9940:SLC1A3
uniprot id: W5PM32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9940:GABRG2
gene id: 9940:GABRG2
uniprot id: W5PX45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRG2 sub-subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:ACTG1
gene id: 9940:ACTG1
uniprot id: A0A3R5SS76
uniprot id: A0A6P3EJ42
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP16
gene id: 9940:USP16
uniprot id: A0A6P3TXF5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. USP16 subfamily.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Homotetramer.
messages: Nucleus
messages: Phosphorylated at the onset of mitosis and dephosphorylated during the metaphase/anaphase transition. Phosphorylation by AURKB enhances the deubiquitinase activity.
messages: Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B.
messages: The UBP-type zinc finger binds 3 zinc ions that form a pair of cross-braced ring fingers encapsulated within a third zinc finger in the primary structure. It recognizes the C-terminal tail of free ubiquitin.

9940:NAA20
gene id: 9940:NAA20
uniprot id: A0A6P3EK88
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTI1
gene id: 9940:TTI1
uniprot id: A0A836A5X7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP52
gene id: 9940:CFAP52
uniprot id: W5NYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP52 family.
messages: cilium axoneme
messages: flagellum

9940:PRELID3B
gene id: 9940:PRELID3B
uniprot id: A0A6P3TJN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOXB9
gene id: 9940:HOXB9
uniprot id: A0A6P3EHB8
uniprot id: W5PA98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PABPC5
gene id: 9940:PABPC5
uniprot id: A0A6P3ENF6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105776
gene id: 9940:LOC101105776
uniprot id: A0A6P3EL19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GSDMA
gene id: 9940:GSDMA
uniprot id: W5PS33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9940:PPWD1
gene id: 9940:PPWD1
uniprot id: A0A6P3EHA7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108077
gene id: 9940:LOC101108077
uniprot id: W5Q753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:C11H17orf98
gene id: 9940:C11H17orf98
uniprot id: A0A6P7EIZ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CMKLR2
gene id: 9940:CMKLR2
uniprot id: A0A6P3TJR2
uniprot id: A0A836D5R6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC6A17
gene id: 9940:SLC6A17
uniprot id: A0A6P3TDR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GORAB
gene id: 9940:GORAB
uniprot id: A0A6P3EI05
names: Caution
names: Similarity
messages: Belongs to the GORAB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A27
gene id: 9940:SLC25A27
uniprot id: J7H8Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:RABAC1
gene id: 9940:RABAC1
uniprot id: C5IJ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

9940:HEATR1
gene id: 9940:HEATR1
uniprot id: W5P0K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEATR1/UTP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9940:RPL26
gene id: 9940:RPL26
uniprot id: A0A6P3ED73
uniprot id: W5QEJ5
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102276
gene id: 9940:LOC101102276
uniprot id: W5P6G2
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

9940:DIPK2B
gene id: 9940:DIPK2B
uniprot id: A0A6P3ESB9
uniprot id: W5P2W5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC47
gene id: 9940:CCDC47
uniprot id: A0A6P3EHM2
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Rough endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZSCAN29
gene id: 9940:ZSCAN29
uniprot id: A0A6P3TDI7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLMN
gene id: 9940:GLMN
uniprot id: A0A6P3TCK0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC5A3
gene id: 9940:SLC5A3
uniprot id: A0A6P3TRS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9940:CFLAR
gene id: 9940:CFLAR
uniprot id: A0A6P3T9A2
uniprot id: A0A6P7DRY0
names: Caution
names: Similarity
messages: Belongs to the peptidase C14A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:K33
gene id: 9940:K33
uniprot id: A0A6P3CXT2
uniprot id: E3VW77
names: Caution
names: Similarity
messages: Belongs to the intermediate filament family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRMT10C
gene id: 9940:TRMT10C
uniprot id: A0A836D7D5
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: mitochondrion nucleoid

9940:PPAT
gene id: 9940:PPAT
uniprot id: A0A6P3TPV6
uniprot id: W5P1C3
names: Caution
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPE65
gene id: 9940:RPE65
uniprot id: W5PPC6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9940:ACP5
gene id: 9940:ACP5
uniprot id: G3M9U4
names: Cofactor
messages: Binds 2 iron ions per subunit.

9940:TRAK2
gene id: 9940:TRAK2
uniprot id: A0A836AE15
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MUTYH
gene id: 9940:MUTYH
uniprot id: W5NTV5
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs.
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

9940:RNF40
gene id: 9940:RNF40
uniprot id: A0A6P3EGG4
uniprot id: W5PCS0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BRE1 family.
messages: Component of the RNF20/40 complex (also known as BRE1 complex) probably composed of 2 copies of RNF20/BRE1A and 2 copies of RNF40/BRE1B. Interacts with UBE2E1/UBCH6.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105114
gene id: 9940:LOC101105114
uniprot id: W5NXZ1
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:RAC1
gene id: 9940:RAC1
uniprot id: A0A6P9FQI8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THRB
gene id: 9940:THRB
uniprot id: D7RFH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9940:LOC101118574
gene id: 9940:LOC101118574
uniprot id: A0A6P3YS72
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL20
gene id: 9940:IL20
uniprot id: W5P975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9940:CLIC5
gene id: 9940:CLIC5
uniprot id: W5PLA9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9940:DNAAF1
gene id: 9940:DNAAF1
uniprot id: A0A836A0D3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium

9940:ATP1B2
gene id: 9940:ATP1B2
uniprot id: A0A6P3EH60
uniprot id: W5Q1B5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9940:UBE2I
gene id: 9940:UBE2I
uniprot id: A0A836CRH5
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNRPA
gene id: 9940:SNRPA
uniprot id: B2LYL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

9940:CENPH
gene id: 9940:CENPH
uniprot id: W5P6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

9940:CCSER2
gene id: 9940:CCSER2
uniprot id: W5NQC7
names: Similarity
messages: Belongs to the CCSER family.

9940:NACA
gene id: 9940:NACA
uniprot id: A0A6P3E316
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GIPC2
gene id: 9940:GIPC2
uniprot id: A0A6P3E6K7
uniprot id: W5PV71
names: Caution
names: Similarity
messages: Belongs to the GIPC family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL4
gene id: 9940:RPL4
uniprot id: A0A836AHP9
names: Caution
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE4A
gene id: 9940:UBE4A
uniprot id: W5PID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

9940:BLOC1S3
gene id: 9940:BLOC1S3
uniprot id: W5PP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S3 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).
messages: Cytoplasm

9940:VTA1
gene id: 9940:VTA1
uniprot id: W5NTA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

9940:MCM3
gene id: 9940:MCM3
uniprot id: W5PXK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

9940:PAPOLA
gene id: 9940:PAPOLA
uniprot id: W5Q524
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9940:LOC101109184
gene id: 9940:LOC101109184
uniprot id: A0A836ABR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117691
gene id: 9940:LOC101117691
uniprot id: P09578
names: Domain
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

9940:STX7
gene id: 9940:STX7
uniprot id: A0A6P3E6U3
uniprot id: W5PY17
names: Caution
names: Similarity
messages: Belongs to the syntaxin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAR2
gene id: 9940:FAR2
uniprot id: A0A6P3E3M5
uniprot id: A0A6P3TLZ1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUPR1
gene id: 9940:NUPR1
uniprot id: W5NYZ3
names: Similarity
messages: Belongs to the NUPR family.

9940:RPE
gene id: 9940:RPE
uniprot id: W5QCX4
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

9940:RNPS1
gene id: 9940:RNPS1
uniprot id: W5Q9J0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the splicing factor SR family.
messages: Found in mRNA splicing-dependent exon junction complexes (EJC). Found in a post-splicing complex with NXF1, RBM8A, UPF1, UPF2, UPF3A, UPF3B and RNPS1. Component of the heterotrimeric ASAP (apoptosis- and splicing-associated protein) and PSAP complexes consisting of RNPS1, SAP18 and either ACIN1 or PNN, respectively; the ASAP and PSAP complexes probably are formed mutually exclusive. Component of the active spliceosome. Associates with polysomes. Interacts with the cleaved p110 isoform of CDC2L1, CSNK2A1, PNN, SART3, SRP54, SRRM1 and TRA2B/SFRS10.
messages: Nucleus speckle

9940:LOC101105186
gene id: 9940:LOC101105186
uniprot id: A0A6P3EH02
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRN3
gene id: 9940:LRRN3
uniprot id: A0A6P3TRB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HHATL
gene id: 9940:HHATL
uniprot id: W5P0R1
names: Subcellular Location Annotation
messages: Membrane

9940:LOC101110711
gene id: 9940:LOC101110711
uniprot id: A0A6P3EJI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:NDC80
gene id: 9940:NDC80
uniprot id: W5PIP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9940:FXN
gene id: 9940:FXN
uniprot id: W5PU52
names: Similarity
messages: Belongs to the frataxin family.

9940:MPHOSPH10
gene id: 9940:MPHOSPH10
uniprot id: W5Q385
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

9940:BRF2
gene id: 9940:BRF2
uniprot id: W5NS82
names: Similarity
messages: Belongs to the TFIIB family.

9940:CREG1
gene id: 9940:CREG1
uniprot id: A0A836D8C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IGF2BP3
gene id: 9940:IGF2BP3
uniprot id: W5PTV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: P-body
messages: Stress granule

9940:PAG11
gene id: 9940:PAG11
uniprot id: A2SZW3
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:TMEM263
gene id: 9940:TMEM263
uniprot id: W5Q8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

9940:RAB28
gene id: 9940:RAB28
uniprot id: A0A6P3CWX0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AVPR1B
gene id: 9940:AVPR1B
uniprot id: F6N686
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9940:LOC101122532
gene id: 9940:LOC101122532
uniprot id: W5P141
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ENG
gene id: 9940:ENG
uniprot id: A0A6P3EAM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105208
gene id: 9940:LOC101105208
uniprot id: A0A6P3EGG6
uniprot id: W5PGJ7
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CUL5
gene id: 9940:CUL5
uniprot id: W5PMI8
names: Similarity
messages: Belongs to the cullin family.

9940:CISH
gene id: 9940:CISH
uniprot id: A0A6P3EEL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLIN1
gene id: 9940:PLIN1
uniprot id: A0A6P3CWW8
uniprot id: B0FJL8
names: Caution
names: Similarity
messages: Belongs to the perilipin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IRAK2
gene id: 9940:IRAK2
uniprot id: W5P4H5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
messages: Interacts with MYD88. IL-1 stimulation leads to the formation of a signaling complex which dissociates from the IL-1 receptor following the binding of PELI1.

9940:C3H12orf29
gene id: 9940:C3H12orf29
uniprot id: A0A6P3CXU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:F13A1
gene id: 9940:F13A1
uniprot id: W5QAR2
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9940:VTI1A
gene id: 9940:VTI1A
uniprot id: W5PRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9940:DPH6
gene id: 9940:DPH6
uniprot id: W5QFI8
names: Function
names: Similarity
messages: Amidase that catalyzes the last step of diphthamide biosynthesis using ammonium and ATP.
messages: Belongs to the Diphthine--ammonia ligase family.

9940:GALT
gene id: 9940:GALT
uniprot id: A0A6P3E0M4
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107550
gene id: 9940:LOC101107550
uniprot id: A0A836A4T8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTF2
gene id: 9940:MTF2
uniprot id: W5Q531
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9940:CCT7
gene id: 9940:CCT7
uniprot id: A0A6P3EA55
uniprot id: W5PQF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPTY2D1
gene id: 9940:SPTY2D1
uniprot id: A0A6P3EFB1
uniprot id: W5PHX5
names: Caution
names: Similarity
messages: Belongs to the SPT2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105495
gene id: 9940:LOC101105495
uniprot id: W5NQU0
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9940:GSTZ1
gene id: 9940:GSTZ1
uniprot id: A0A6P3E6F5
uniprot id: W5NWM7
names: Caution
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EXOSC9
gene id: 9940:EXOSC9
uniprot id: A0A836AA96
uniprot id: W5PYP7
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BLZF1
gene id: 9940:BLZF1
uniprot id: A0A6P3EB28
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SDAD1
gene id: 9940:SDAD1
uniprot id: A0A6P3E703
uniprot id: W5Q3Y2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:KEF53 p06
gene id: 9940:KEF53_p06
uniprot id: O78753
uniprot id: Q5MA70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM186. Interacts with TMEM242 (By similarity).
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

9940:WDR76
gene id: 9940:WDR76
uniprot id: A0A6P3TH13
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9940:NFKBIA
gene id: 9940:NFKBIA
uniprot id: A0A6P9FQP9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:H1-6
gene id: 9940:H1-6
uniprot id: A0A6P3TCF1
uniprot id: W5QFQ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITGB1
gene id: 9940:ITGB1
uniprot id: B0FYY4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Cell surface
messages: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-4/beta-1 is a receptor for VCAM1 and recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Integrin alpha-3/beta-1 provides a docking site for FAP (seprase) at invadopodia plasma membranes in a collagen-dependent manner and hence may participate in the adhesion, formation of invadopodia and matrix degradation processes, promoting cell invasion. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. When associated with alpha-7/beta-1 integrin, regulates cell adhesion and laminin matrix deposition. Involved in promoting endothelial cell motility and angiogenesis. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process and the formation of mineralized bone nodules. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and RACK1, …
messages: Interacts with seprase FAP (seprase); the interaction occurs at the cell surface of invadopodia membrane in a collagen-dependent manner (By similarity). Heterodimer of an alpha and a beta subunit. Beta-1 associates with either alpha-1, alpha-2, alpha-3, alpha-4, alpha-5, alpha-6, alpha-7, alpha-8, alpha-9, alpha-10, alpha-11 or alpha-V. ITGA6:ITGB1 is found in a complex with CD9; interaction takes place in oocytes and is involved in sperm-egg fusion. Binds LGALS3BP and NMRK2, when associated with alpha-7, but not with alpha-5. Interacts with FLNA, FLNB, FLNC and RANBP9. Interacts with KRT1 in the presence of RACK1 and SRC. Interacts with JAML; integrin alpha-4/beta-1 may regulate leukocyte to endothelial cells adhesion by controlling JAML homodimerization. Interacts with RAB21. Interacts (via the cytoplasmic region) with RAB25 (via the hypervariable C-terminal region). Interacts with MYO10. Interacts with ITGB1BP1 (via C-terminal region); the interaction is a prerequisite for focal adhesion disassembly. Interacts with TLN1; the interaction is prevented by competitive binding of ITGB1BP1. Interacts with ACAP1; required for ITGB1 recycling. Interacts with ASAP3. Interacts with FERMT2; the interaction is inhibited in presence of ITGB1BP1. Interacts with DAB2. Interacts with FGR and HCK. Isoform 2 interacts with alpha-7A and alpha-7B in adult skeletal muscle. Isoform 2 interacts with alpha-7B in cardiomyocytes of adult heart. Interacts with EMP2; the interaction may be direct or indirect and ITGB1 has a heterodimer form (By similarity). ITGA5:ITGB1 interacts with CCN3 (By similarity). ITGA4:ITGB1 is found in a ternary complex with CX3CR1 and CX3CL1 (By similarity). ITGA5:ITGB1 interacts with FBN1 (By similarity). ITGA5:ITGB1 interacts with IL1B. Interacts with MDK. ITGA4:ITGB1 interacts with MDK; this interaction mediates MDK-induced osteoblast cells migration through PXN phosphorylation. ITGA6:ITGB1 interacts with MDK; this interaction mediates MDK-induced neurite-outg…
messages: Melanosome
messages: Recycling endosome
messages: The cysteine residues are involved in intrachain disulfide bonds.
messages: focal adhesion
messages: invadopodium membrane
messages: lamellipodium
messages: ruffle
messages: ruffle membrane

9940:CNPY2
gene id: 9940:CNPY2
uniprot id: A0A6P3E326
uniprot id: W5PI22
names: Caution
names: Similarity
messages: Belongs to the canopy family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EXOC5
gene id: 9940:EXOC5
uniprot id: A0A6P3E6B4
names: Caution
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DPYSL5
gene id: 9940:DPYSL5
uniprot id: W5QCG2
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9940:LOC101108512
gene id: 9940:LOC101108512
uniprot id: W5P8F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101106847
gene id: 9940:LOC101106847
uniprot id: A0A836AFJ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CASP7
gene id: 9940:CASP7
uniprot id: W5PTI1
names: Similarity
messages: Belongs to the peptidase C14A family.

9940:SLC26A2
gene id: 9940:SLC26A2
uniprot id: Q9GJY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

9940:PKIB
gene id: 9940:PKIB
uniprot id: A0A6P3TPS1
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9940:ENO1
gene id: 9940:ENO1
uniprot id: W5PIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9940:PSME2
gene id: 9940:PSME2
uniprot id: W5QD41
names: Similarity
messages: Belongs to the PA28 family.

9940:RALA
gene id: 9940:RALA
uniprot id: A0A6P3E902
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

9940:INTS2
gene id: 9940:INTS2
uniprot id: W5Q1T0
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9940:TSHB
gene id: 9940:TSHB
uniprot id: W5QFW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9940:AGO3
gene id: 9940:AGO3
uniprot id: W5QEB1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9940:LIG4
gene id: 9940:LIG4
uniprot id: A0A6P9FR67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9940:CCDC174
gene id: 9940:CCDC174
uniprot id: A0A6P3ENE5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IPPK
gene id: 9940:IPPK
uniprot id: A0A836D562
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MID1
gene id: 9940:MID1
uniprot id: A0A6P3EMM6
uniprot id: A0A6P3TH99
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:PPP2R3C
gene id: 9940:PPP2R3C
uniprot id: A0A6P3EEA9
uniprot id: W5PBL2
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SH3BGRL3
gene id: 9940:SH3BGRL3
uniprot id: A0A6P3E9B1
names: Caution
names: Similarity
messages: Belongs to the SH3BGR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KDELR2
gene id: 9940:KDELR2
uniprot id: A0A6P3EGJ9
uniprot id: W5NVW1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119226
gene id: 9940:LOC101119226
uniprot id: A0A6P3E739
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDGFRL
gene id: 9940:PDGFRL
uniprot id: W5PHH5
names: Subcellular Location Annotation
names: Subunit
messages: Forms a complex composed of PDGFRL, TNK2 and GRB2.
messages: Secreted

9940:PRMT2
gene id: 9940:PRMT2
uniprot id: A0A836AQN4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK14
gene id: 9940:CDK14
uniprot id: A0A6P3YHB8
uniprot id: W5Q4F4
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115110
gene id: 9940:LOC101115110
uniprot id: W5QGH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9940:SEMA4F
gene id: 9940:SEMA4F
uniprot id: W5PTL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:HMGN3
gene id: 9940:HMGN3
uniprot id: A0A6P3E8B0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. Affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion. Regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors. Regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. May play a role in ocular development and astrocyte function.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IGFBP2
gene id: 9940:IGFBP2
uniprot id: Q29400
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Binds IGF2 more than IGF1.
messages: Expressed in abundance in selected adult tissues, namely liver, kidney, adrenal, pituitary and choroid plexus.
messages: Inhibits IGF-mediated growth and developmental rates (By similarity). IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: O-glycosylated.
messages: Secreted
messages: The C-terminus is required for IGF-binding and growth inhibition.

9940:TXNRD1
gene id: 9940:TXNRD1
uniprot id: A0A6P3TBU6
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

9940:AP2B1
gene id: 9940:AP2B1
uniprot id: A0A6P3EI53
uniprot id: A0A6P3THQ3
names: Caution
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMC6
gene id: 9940:PSMC6
uniprot id: W5Q805
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

9940:ZFP36
gene id: 9940:ZFP36
uniprot id: A0A836A151
uniprot id: Q6S9E0
names: Caution
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Associates with cytoplasmic CCR4-NOT and PAN2-PAN3 deadenylase complexes to trigger ARE-containing mRNA deadenylation and decay processes. Part of a mRNA decay activation complex at least composed of poly(A)-specific exoribonucleases CNOT6, EXOSC2 and XRN1 and mRNA-decapping enzymes DCP1A and DCP2. Associates with the RNA exosome complex. Interacts (via phosphorylated form) with 14-3-3 proteins; these interactions promote exclusion of ZFP36 from cytoplasmic stress granules in response to arsenite treatment in a MAPKAPK2-dependent manner and does not prevent CCR4-NOT deadenylase complex recruitment or ZFP36-induced ARE-containing mRNA deadenylation and decay processes. Interacts with 14-3-3 proteins; these interactions occur in response to rapamycin in an Akt-dependent manner. Interacts with AGO2 and AGO4. Interacts (via C-terminus) with CNOT1; this interaction occurs in a RNA-independent manner and induces mRNA deadenylation. Interacts (via N-terminus) with CNOT6. Interacts with CNOT6L. Interacts (via C-terminus) with CNOT7; this interaction occurs in a RNA-independent manner, induces mRNA deadenylation and is inhibited in a phosphorylation MAPKAPK2-dependent manner. Interacts (via unphosphorylated form) with CNOT8; this interaction occurs in a RNA-independent manner and is inhibited in a phosphorylation MAPKAPK2-dependent manner. Interacts with DCP1A. Interacts (via N-terminus) with DCP2. Interacts with EDC3. Interacts (via N-terminus) with EXOSC2. Interacts with heat shock 70 kDa proteins. Interacts with KHSRP; this interaction increases upon cytokine-induced treatment. Interacts with MAP3K4; this interaction enhances the association with SH3KBP1/CIN85. Interacts with MAPKAPK2; this interaction occurs upon skeletal muscle satellite cell activation. Interacts with NCL. Interacts with NUP214; this interaction increases upon lipopolysaccharide (LPS) stimulation. Interacts with PABPC1; this interaction occurs in a RNA-dependent manner. Interacts (via hypophosphorylate…
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: Nucleus
messages: P-body
messages: Phosphorylated. Phosphorylation at serine and/or threonine residues occurs in a p38 MAPK- and MAPKAPK2-dependent manner. Phosphorylated by MAPKAPK2 at Ser-58 and Ser-184; phosphorylation increases its stability and cytoplasmic localization, promotes binding to 14-3-3 adapter proteins and inhibits the recruitment of cytoplasmic CCR4-NOT and PAN2-PAN3 deadenylase complexes to the mRNA decay machinery, thereby inhibiting ZFP36-induced ARE-containing mRNA deadenylation and decay processes. Phosphorylation by MAPKAPK2 does not impair ARE-containing RNA-binding. Phosphorylated in a MAPKAPK2- and p38 MAPK-dependent manner upon skeletal muscle satellite cell activation; this phosphorylation inhibits ZFP36-mediated mRNA decay activity, and hence stabilizes MYOD1 mRNA. Phosphorylated by MAPK1 upon mitogen stimulation. Phosphorylated at Ser-64 and Ser-91; these phosphorylations increase in a SH3KBP1-dependent manner. Phosphorylated at serine and threonine residues in a pyruvate kinase PKM- and p38 MAPK-dependent manner. Phosphorylation at Ser-58 may participate in the PKM-mediated degradation of ZFP36 in a p38 MAPK-dependent manner. Dephosphorylated by serine/threonine phosphatase 2A at Ser-184.
messages: The C3H1-type zinc finger domains are necessary for ARE-binding activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitinated; pyruvate kinase (PKM)-dependent ubiquitination leads to proteasomal degradation through a p38 MAPK signaling pathway.
messages: Zinc-finger RNA-binding protein that destabilizes numerous cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as an 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Recruits deadenylase CNOT7 (and probably the CCR4-NOT complex) via association with CNOT1, and hence promotes ARE-mediated mRNA deadenylation. Functions also by recruiting components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs. Self regulates by destabilizing its own mRNA. Binds to 3'-UTR ARE of numerous mRNAs. Binds also to ARE of its own mRNA. Plays a role in anti-inflammatory responses; suppresses tumor necrosis factor (TNF)-alpha production by stimulating ARE-mediated TNF-alpha mRNA decay and several other inflammatory ARE-containing mRNAs in interferon (IFN)- and/or lipopolysaccharide (LPS)-induced macrophages. Also plays a role in the regulation of dendritic cell maturation at the post-transcriptional level, and hence operates as part of a negative feedback loop to limit the inflammatory response. Promotes ARE-mediated mRNA decay of hypoxia-inducible factor HIF1A mRNA during the response of endothelial cells to hypoxia. Positively regulates early adipogenesis of preadipocytes by promoting ARE-mediated mRNA decay of immediate early genes (IEGs). Negatively regulates hematopoietic/erythroid cell differentiation by promoting ARE-mediated mRNA decay of the transcription factor STAT5B mRNA. Plays a role in maintaining skeletal muscle satellite cell quiescence by promoting ARE-mediated mRNA decay of the myogenic determination factor MYOD1 mRNA. Associates also with and regulates the expression of non-ARE-containing target mRNAs at the post-transcriptional level, such as MHC class I mRNAs. Participates in association with argonaute RISC catalytic components in the ARE…
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9940:PARN
gene id: 9940:PARN
uniprot id: A0A6P3EQP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMOD3
gene id: 9940:TMOD3
uniprot id: A0A6P3EB32
uniprot id: A0A6P7DVB0
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:RPS20
gene id: 9940:RPS20
uniprot id: A0A6P3EG90
uniprot id: W5PZT4
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105553
gene id: 9940:LOC101105553
uniprot id: A0A6P3ESK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RutC family.
messages: Catalyzes the hydrolytic deamination of enamine/imine intermediates that form during the course of normal metabolism. May facilitate the release of ammonia from these potentially toxic reactive metabolites, reducing their impact on cellular components. It may act on enamine/imine intermediates formed by several types of pyridoxal-5'-phosphate-dependent dehydratases including L-threonine dehydratase.
messages: Peroxisome

9940:SFXN2
gene id: 9940:SFXN2
uniprot id: A0A6P3YSG6
uniprot id: W5NUR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSPAN19
gene id: 9940:TSPAN19
uniprot id: W5Q171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:SLC35B3
gene id: 9940:SLC35B3
uniprot id: W5Q5U3
uniprot id: W5Q5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

9940:DRAM1
gene id: 9940:DRAM1
uniprot id: A0A6P3E817
uniprot id: W5Q1K2
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMED7
gene id: 9940:TMED7
uniprot id: W5Q4H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9940:APEX1
gene id: 9940:APEX1
uniprot id: W5QEQ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9940:CDCA7
gene id: 9940:CDCA7
uniprot id: W5NR01
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:VSIG1
gene id: 9940:VSIG1
uniprot id: W5QAU4
names: Subcellular Location Annotation
messages: Membrane

9940:SLC25A30
gene id: 9940:SLC25A30
uniprot id: W5PCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:TIMELESS
gene id: 9940:TIMELESS
uniprot id: B3F207
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

9940:DNAJC19
gene id: 9940:DNAJC19
uniprot id: A0A6P3TD92
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121718
gene id: 9940:LOC101121718
uniprot id: A0A6P3ES39
uniprot id: W5PFW3
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V1H
gene id: 9940:ATP6V1H
uniprot id: W5PWF2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:CARTPT
gene id: 9940:CARTPT
uniprot id: W5P5A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

9940:THOC6
gene id: 9940:THOC6
uniprot id: A0A6P3EQM7
uniprot id: W5NS02
names: Caution
names: Similarity
messages: Belongs to the WD repeat THOC6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RSL24D1
gene id: 9940:RSL24D1
uniprot id: A0A6P3EB30
uniprot id: W5QIC0
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPA4
gene id: 9940:HSPA4
uniprot id: A0A6P3E5W0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADCK1
gene id: 9940:ADCK1
uniprot id: W5NXI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

9940:ACTR6
gene id: 9940:ACTR6
uniprot id: A0A6P3E3F3
names: Caution
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNB2
gene id: 9940:CCNB2
uniprot id: A0A6P3EB16
uniprot id: W5QI44
names: Caution
names: Similarity
messages: Belongs to the cyclin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FASLG
gene id: 9940:FASLG
uniprot id: W5PYV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

9940:TTC19
gene id: 9940:TTC19
uniprot id: W5Q7H9
names: Similarity
messages: Belongs to the TTC19 family.

9940:LOC101106452
gene id: 9940:LOC101106452
uniprot id: W5PTN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

9940:ASIP
gene id: 9940:ASIP
uniprot id: A0A6P3CX05
uniprot id: B4YAJ9
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN8
gene id: 9940:CLDN8
uniprot id: W5NSC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9940:DTWD1
gene id: 9940:DTWD1
uniprot id: A0A836A112
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP97
gene id: 9940:CFAP97
uniprot id: A0A6P3T6J7
names: Similarity
messages: Belongs to the CFAP97 family.

9940:PHC2
gene id: 9940:PHC2
uniprot id: W5QI39
names: Subcellular Location Annotation
messages: Nucleus

9940:POPDC2
gene id: 9940:POPDC2
uniprot id: W5QEV1
names: Similarity
messages: Belongs to the popeye family.

9940:PTPN14
gene id: 9940:PTPN14
uniprot id: W5PGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9940:AANAT
gene id: 9940:AANAT
uniprot id: Q29495
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the acetyltransferase family. AANAT subfamily.
messages: Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
messages: Cytoplasm
messages: Exhibits night/day variations with a 7-fold increased activity at night. At the mRNA level, the nocturnal increase is lower than 2-fold.
messages: Highest expression in the pineal gland, followed by retina. Expressed at much lower levels in brainstem and pituitary gland. AANAT activity also detected at low levels in the olfactory lobe.
messages: Monomer. Interacts with several 14-3-3 proteins, including YWHAB, YWHAE, YWHAG and YWHAZ, preferentially when phosphorylated at Thr-31. Phosphorylation on Ser-205 also allows binding to YWHAZ, but with a 10-fold lower affinity. The interaction with YWHAZ considerably increases affinity for arylalkylamines and acetyl-CoA and protects the enzyme from dephosphorylation and proteasomal degradation. It may also prevent thiol-dependent inactivation. The physiological stoichiometry of the interaction is not clear. In vitro studies show either 1:2 (i.e. 1 AANAT molecule per YWHAZ dimer) (PubMed:11427721) or 2:2 (PubMed:11336675).
messages: cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins.

9940:LOC101115733
gene id: 9940:LOC101115733
uniprot id: A0A6P3EB15
names: Caution
names: Similarity
messages: Belongs to the histone H2B family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EGLN3
gene id: 9940:EGLN3
uniprot id: A0A6P3EBW3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS13C
gene id: 9940:VPS13C
uniprot id: W5QI22
names: Similarity
messages: Belongs to the VPS13 family.

9940:LZTFL1
gene id: 9940:LZTFL1
uniprot id: A0A6P3EEN6
uniprot id: W5PIK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114408
gene id: 9940:LOC101114408
uniprot id: W5PW57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9940:HDHD3
gene id: 9940:HDHD3
uniprot id: A0A836AMB3
uniprot id: W5NY82
names: Caution
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLGRKT
gene id: 9940:PLGRKT
uniprot id: A0A6P3E9C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CES4A
gene id: 9940:CES4A
uniprot id: A0A836A1J8
uniprot id: W5NXC6
names: Caution
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPRG1
gene id: 9940:TPRG1
uniprot id: W5QH01
names: Similarity
messages: Belongs to the TPRG1 family.

9940:ITGAV
gene id: 9940:ITGAV
uniprot id: B0FYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:H3F3A
gene id: 9940:H3F3A
uniprot id: A0A6P3EHQ7
uniprot id: W5Q8W8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MEOX1
gene id: 9940:MEOX1
uniprot id: W5P6W7
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101123441
gene id: 9940:LOC101123441
uniprot id: A0A6P3E1G5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DPYD
gene id: 9940:DPYD
uniprot id: W5Q7Y9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

9940:DHX58
gene id: 9940:DHX58
uniprot id: W5QAJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9940:LOC101102539
gene id: 9940:LOC101102539
uniprot id: A0A6P3YTL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOB1
gene id: 9940:NOB1
uniprot id: W5P0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

9940:ATP6V1B1
gene id: 9940:ATP6V1B1
uniprot id: W5PNV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9940:NDFIP2
gene id: 9940:NDFIP2
uniprot id: W5NQH9
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9940:UCN3
gene id: 9940:UCN3
uniprot id: W5P3E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9940:PIN4
gene id: 9940:PIN4
uniprot id: A0A6P3ESI8
uniprot id: W5Q8J0
names: Caution
names: Similarity
messages: Belongs to the PpiC/parvulin rotamase family. PIN4 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122645
gene id: 9940:LOC101122645
uniprot id: A0A6P3DZG8
uniprot id: W5PUU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DSC1
gene id: 9940:DSC1
uniprot id: W5P9V7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9940:ATP1A1
gene id: 9940:ATP1A1
uniprot id: A0A836D9U0
uniprot id: P04074
names: Activity Regulation
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Melanosome
messages: Membrane
messages: Phosphorylation on Tyr-10 modulates pumping activity. Phosphorylation of Ser-941 by PKA modulates the response of ATP1A1 to PKC (By similarity). Dephosphorylation by protein phosphatase 2A (PP2A) following increases in intracellular sodium, leading to increase catalytic activity (By similarity).
messages: Specifically inhibited by cardiac glycosides such as digoxin or ouabain.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The sodium/potassium-transporting ATPase is composed of a catalytic alpha subunit, an auxiliary non-catalytic beta subunit and an additional regulatory subunit. Interacts with regulatory subunit FXYD1. Interacts with regulatory subunit FXYD3. Interacts with SIK1. Interacts with SLC35G1 and STIM1. Interacts with CLN3; this interaction regulates the sodium/potassium-transporting ATPase complex localization at the plasma membrane (By similarity).
messages: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients.
messages: axon
messages: sarcolemma

9940:OARD1
gene id: 9940:OARD1
uniprot id: A0A6P3THU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BRS3
gene id: 9940:BRS3
uniprot id: O97967
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Role in sperm cell division, maturation, or function. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).

9940:RWDD2A
gene id: 9940:RWDD2A
uniprot id: A0A6P3EGN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSPAN12
gene id: 9940:TSPAN12
uniprot id: A0A6P3EC22
uniprot id: A0A6P7E0P9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HTRA2
gene id: 9940:HTRA2
uniprot id: W5PTC7
names: Similarity
messages: Belongs to the peptidase S1C family.

9940:CALHM4
gene id: 9940:CALHM4
uniprot id: A0A836A1S6
uniprot id: W5PHM3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AIMP2
gene id: 9940:AIMP2
uniprot id: C5IWT6
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

9940:PEPD
gene id: 9940:PEPD
uniprot id: A0A6P3E9Q2
uniprot id: W5P2V3
names: Caution
names: Similarity
messages: Belongs to the peptidase M24B family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YIPF5
gene id: 9940:YIPF5
uniprot id: W5NVS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9940:FTH1
gene id: 9940:FTH1
uniprot id: A0A6P9FNB3
uniprot id: K4PF69
names: Caution
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC7A7
gene id: 9940:SLC7A7
uniprot id: A0A6P3E7G0
uniprot id: A0A6P3EFM3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBM23
gene id: 9940:RBM23
uniprot id: A0A6P3TFG8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTG2
gene id: 9940:ACTG2
uniprot id: W5PRA1
names: Similarity
messages: Belongs to the actin family.

9940:LOC101114750
gene id: 9940:LOC101114750
uniprot id: W5P8N0
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

9940:CHCHD4
gene id: 9940:CHCHD4
uniprot id: W5NSY3
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

9940:AVIL
gene id: 9940:AVIL
uniprot id: A0A6P3E2Z0
names: Caution
names: Similarity
messages: Belongs to the villin/gelsolin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FZR1
gene id: 9940:FZR1
uniprot id: W5PSG6
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9940:RNF121
gene id: 9940:RNF121
uniprot id: A0A6P3ED39
uniprot id: W5NZA6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMAD4
gene id: 9940:SMAD4
uniprot id: A0A6P7DER8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9940:ACTL7A
gene id: 9940:ACTL7A
uniprot id: A0A6P3YHC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Golgi apparatus
messages: May play an important role in formation and fusion of Golgi-derived vesicles during acrosome biogenesis.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:FOLR3
gene id: 9940:FOLR3
uniprot id: A0A6P3EKR2
names: Caution
names: Similarity
messages: Belongs to the folate receptor family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL2BP
gene id: 9940:ARL2BP
uniprot id: C5IWU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARL2BP family.
messages: Cytoplasm
messages: Mitochondrion intermembrane space
messages: Nucleus
messages: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
messages: centrosome
messages: cilium basal body

9940:LOC101116222
gene id: 9940:LOC101116222
uniprot id: W5QAE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TLR1
gene id: 9940:TLR1
uniprot id: A0A6P3CX63
uniprot id: B5DC86
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CGGBP1
gene id: 9940:CGGBP1
uniprot id: A0A6P3DZG4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNR1
gene id: 9940:CNR1
uniprot id: A0A6P3EFW6
uniprot id: W5QFH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids, including endocannabinoids (eCBs), such as N-arachidonoylethanolamide (also called anandamide or AEA) and 2-arachidonoylglycerol (2-AG). Signaling typically involves reduction in cyclic AMP.
messages: Interacts (via C-terminus) with CNRIP1.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: axon

9940:LOC101115664
gene id: 9940:LOC101115664
uniprot id: A0A6P3EDI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A13
gene id: 9940:SLC39A13
uniprot id: C7BDW6
names: Subcellular Location Annotation
messages: Membrane

9940:PDIA3
gene id: 9940:PDIA3
uniprot id: C6JUQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

9940:CNOT9
gene id: 9940:CNOT9
uniprot id: W5QED0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

9940:ACAD10
gene id: 9940:ACAD10
uniprot id: W5QBS0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9940:LOC105603737
gene id: 9940:LOC105603737
uniprot id: W5PSU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9940:NTPCR
gene id: 9940:NTPCR
uniprot id: A0A6P3EM20
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPYC
gene id: 9940:EPYC
uniprot id: W5Q2B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

9940:SAR1A
gene id: 9940:SAR1A
uniprot id: W5P7A1
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

9940:DDX5
gene id: 9940:DDX5
uniprot id: A0A6P3E891
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUF2
gene id: 9940:NUF2
uniprot id: A0A6P3THP9
names: Similarity
messages: Belongs to the NUF2 family.

9940:C1H1orf162
gene id: 9940:C1H1orf162
uniprot id: A0A836AP11
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ABAT
gene id: 9940:ABAT
uniprot id: W5P5B2
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

9940:C5H19orf53
gene id: 9940:C5H19orf53
uniprot id: A0A6P3E993
uniprot id: W5PEA8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UPF0390 family.
messages: May have a potential role in hypercalcemia of malignancy.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPT1B
gene id: 9940:CPT1B
uniprot id: A0A6P9FN97
uniprot id: Q8SPI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEMA3C
gene id: 9940:SEMA3C
uniprot id: W5Q605
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:LOC101112822
gene id: 9940:LOC101112822
uniprot id: A0A6P3E5Y5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C19H3orf62
gene id: 9940:C19H3orf62
uniprot id: A0A835ZPH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEPT1
gene id: 9940:CEPT1
uniprot id: A0A6P3DYP6
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9940:CALM3
gene id: 9940:CALM3
uniprot id: A0A6P7ECH5
uniprot id: Q6YNX6
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calmodulin family.
messages: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding. Acts as a sensor to modulate the endoplasmic reticulum contacts with other organelles mediated by VMP1:ATP2A2.
messages: Interacts with CEP97, CCP110, TTN/titin and SRY. Interacts with MYO5A and RRAD (By similarity). Interacts with USP6; the interaction is calcium dependent (By similarity). Interacts with CDK5RAP2. Interacts with SCN5A. Interacts with RYR1 and RYR2 (By similarity). Interacts with FCHO1. Interacts with MIP in a 1:2 stoichiometry; the interaction with the cytoplasmic domains from two MIP subunits promotes MIP water channel closure. Interacts with ORAI1; this may play a role in the regulation of ORAI1-mediated calcium transport. Interacts with SYT7 (By similarity). Interacts with MYO10 and MYO1C (By similarity). Interacts with SLC9A1 in a calcium-dependent manner (By similarity). Interacts with HINT1; interaction increases in the presence of calcium ions (By similarity). Interacts with HINT3 (By similarity).
messages: Phosphorylation results in a decreased activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein has four functional calcium-binding sites.
messages: Ubiquitination results in a strongly decreased activity.
messages: spindle
messages: spindle pole

9940:MMACHC
gene id: 9940:MMACHC
uniprot id: A0A6P3E680
uniprot id: W5NUC6
names: Caution
names: Similarity
messages: Belongs to the MMACHC family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NEU1
gene id: 9940:NEU1
uniprot id: A0A835ZW35
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC100144429
gene id: 9940:LOC100144429
uniprot id: Q9XSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S1 family. Tryptase subfamily.
messages: Homotetramer.
messages: Secreted
messages: Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type.

9940:GRAP2
gene id: 9940:GRAP2
uniprot id: W5Q6L9
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

9940:CWC27
gene id: 9940:CWC27
uniprot id: A0A6P3ELM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM229B
gene id: 9940:FAM229B
uniprot id: A0A836A7V2
uniprot id: W5PIU3
names: Caution
names: Similarity
messages: Belongs to the FAM229 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GAB1
gene id: 9940:GAB1
uniprot id: A0A6P3EHN8
uniprot id: W5PMU7
uniprot id: W5PMU8
names: Caution
names: Similarity
messages: Belongs to the GAB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TESMIN
gene id: 9940:TESMIN
uniprot id: A0A835ZPP1
uniprot id: W5Q3N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNRNPA2B1
gene id: 9940:HNRNPA2B1
uniprot id: A0A6P3TRD9
uniprot id: W5PK95
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasmic granule
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular exosome

9940:GJA1
gene id: 9940:GJA1
uniprot id: A0A6P3E6K2
uniprot id: W5QFD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with SGSM3 (By similarity). Interacts with RIC1/CIP150 (By similarity). Interacts with CNST and CSNK1D (By similarity). Interacts (via C-terminus) with TJP1. Interacts (via C-terminus) with SRC (via SH3 domain). Interacts (not ubiquitinated) with UBQLN4 (via UBA domain) (By similarity). Interacts with NOV. Interacts with TMEM65.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Endoplasmic reticulum
messages: Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles.
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: gap junction

9940:CDKL4
gene id: 9940:CDKL4
uniprot id: W5PEQ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:PDE6A
gene id: 9940:PDE6A
uniprot id: W5P7F2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9940:FBN2
gene id: 9940:FBN2
uniprot id: W5Q6X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9940:RAMP3
gene id: 9940:RAMP3
uniprot id: A0A6P3EC07
names: Caution
names: Similarity
messages: Belongs to the RAMP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDF2
gene id: 9940:GDF2
uniprot id: W5NSX1
names: Similarity
messages: Belongs to the TGF-beta family.

9940:GHITM
gene id: 9940:GHITM
uniprot id: A0A6P3ERF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9940:S100A10
gene id: 9940:S100A10
uniprot id: A0A6P3YGV7
uniprot id: W5QIU9
names: Caution
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYOZ2
gene id: 9940:MYOZ2
uniprot id: E5FXR5
names: Similarity
messages: Belongs to the myozenin family.

9940:IL7R
gene id: 9940:IL7R
uniprot id: A0A836A300
uniprot id: W5PNL9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102703
gene id: 9940:LOC101102703
uniprot id: A0A6P3E1W3
uniprot id: W5NXX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHCG
gene id: 9940:RHCG
uniprot id: E5G6E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9940:ZNF605
gene id: 9940:ZNF605
uniprot id: A0A6P3T1W2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHIC2
gene id: 9940:CHIC2
uniprot id: A0A6P3E5I6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105603799
gene id: 9940:LOC105603799
uniprot id: A0A6P3T824
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHIA
gene id: 9940:CHIA
uniprot id: W5QE46
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

9940:MARF1
gene id: 9940:MARF1
uniprot id: W5PFL4
names: Subcellular Location Annotation
messages: Peroxisome

9940:HLTF
gene id: 9940:HLTF
uniprot id: A0A6P3T8D6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGXT2
gene id: 9940:AGXT2
uniprot id: W5PPB3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9940:RETREG3
gene id: 9940:RETREG3
uniprot id: A0A6P3EDJ9
uniprot id: W5NX77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UPP1
gene id: 9940:UPP1
uniprot id: W5Q3H9
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

9940:LOC780772
gene id: 9940:LOC780772
uniprot id: Q5G2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9940:CCR5
gene id: 9940:CCR5
uniprot id: W5PXT0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:MED28
gene id: 9940:MED28
uniprot id: W5P035
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

9940:ABHD3
gene id: 9940:ABHD3
uniprot id: A0A6P3EDW6
uniprot id: W5PF35
names: Caution
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAS2R42
gene id: 9940:TAS2R42
uniprot id: A0A218KHX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9940:PIM1
gene id: 9940:PIM1
uniprot id: C0JAN8
uniprot id: C0JAN9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation.

9940:NPAS4
gene id: 9940:NPAS4
uniprot id: A0A6P9FRH5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105601864
gene id: 9940:LOC105601864
uniprot id: W5QFS6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:CETN3
gene id: 9940:CETN3
uniprot id: A0A6P3EEG7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHOF
gene id: 9940:RHOF
uniprot id: A0A6P3T1P6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CIAO1
gene id: 9940:CIAO1
uniprot id: A0A6P3EA98
uniprot id: W5PX14
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BAD
gene id: 9940:BAD
uniprot id: A0A6P3TF80
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPA4L
gene id: 9940:HSPA4L
uniprot id: W5Q334
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9940:LOC101114018
gene id: 9940:LOC101114018
uniprot id: A0A6P7EG13
uniprot id: W5PD15
names: Caution
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9940:WLS
gene id: 9940:WLS
uniprot id: A0A6P3DYE1
uniprot id: W5PP24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123341
gene id: 9940:LOC101123341
uniprot id: W5PJ59
names: Similarity
messages: Belongs to the SH3BGR family.

9940:KDM4C
gene id: 9940:KDM4C
uniprot id: W5PW64
names: Similarity
messages: Belongs to the JHDM3 histone demethylase family.

9940:LOC101108423
gene id: 9940:LOC101108423
uniprot id: A0A6P3EDX0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMBIM1
gene id: 9940:TMBIM1
uniprot id: A0A6P7DQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9940:INTS4
gene id: 9940:INTS4
uniprot id: A0A6P3EQC6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SH2D1B
gene id: 9940:SH2D1B
uniprot id: A0A6P3DZW2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NINJ1
gene id: 9940:NINJ1
uniprot id: W5PE42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

9940:LOC101106806
gene id: 9940:LOC101106806
uniprot id: A0A6P3TCG9
names: Function
names: Similarity
messages: Belongs to the CMP-Neu5Ac hydroxylase family.
messages: Sialic acids are components of carbohydrate chains of glycoconjugates and are involved in cell-cell recognition and cell-pathogen interactions. Catalyzes the conversion of CMP-N-acetylneuraminic acid (CMP-Neu5Ac) into its hydroxylated derivative CMP-N-glycolylneuraminic acid (CMP-Neu5Gc), a sialic acid abundantly expressed at the surface of many cells.

9940:KCNE3
gene id: 9940:KCNE3
uniprot id: A0A6P3T0S6
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9940:MBOAT1
gene id: 9940:MBOAT1
uniprot id: W5PJK8
names: Subcellular Location Annotation
messages: Membrane

9940:RPL3
gene id: 9940:RPL3
uniprot id: A0A6P3E411
uniprot id: W5Q4S3
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OLFML3
gene id: 9940:OLFML3
uniprot id: W5QFB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:HOATZ
gene id: 9940:HOATZ
uniprot id: A0A835ZR24
uniprot id: W5PXG7
names: Caution
names: Similarity
messages: Belongs to the HOATZ family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCT5
gene id: 9940:CCT5
uniprot id: A0A6P3ELX6
uniprot id: W5PXX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBP1
gene id: 9940:FBP1
uniprot id: A0A6P3E7V5
uniprot id: W5PFR8
names: Caution
names: Similarity
messages: Belongs to the FBPase class 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105613617
gene id: 9940:LOC105613617
uniprot id: W5NR64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ZKSCAN8
gene id: 9940:ZKSCAN8
uniprot id: W5Q9D1
names: Subcellular Location Annotation
messages: Nucleus

9940:CTSF
gene id: 9940:CTSF
uniprot id: W5PBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9940:SARAF
gene id: 9940:SARAF
uniprot id: W5PKS2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Interacts with STIM1; the interaction is inhibit by th interaction of STIM1 with EFHB.
messages: Membrane
messages: Negative regulator of store-operated Ca(2+) entry (SOCE) involved in protecting cells from Ca(2+) overfilling. In response to cytosolic Ca(2+) elevation after endoplasmic reticulum Ca(2+) refilling, promotes a slow inactivation of STIM (STIM1 or STIM2)-dependent SOCE activity: possibly act by facilitating the deoligomerization of STIM to efficiently turn off ORAI when the endoplasmic reticulum lumen is filled with the appropriate Ca(2+) levels, and thus preventing the overload of the cell with excessive Ca(2+) ions.

9940:ADAMTS20
gene id: 9940:ADAMTS20
uniprot id: W5QEN0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9940:PUS7L
gene id: 9940:PUS7L
uniprot id: W5QEJ8
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

9940:CDK20
gene id: 9940:CDK20
uniprot id: A0A6P3E7T4
uniprot id: W5PCQ1
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STEAP2
gene id: 9940:STEAP2
uniprot id: W5PQR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9940:IK
gene id: 9940:IK
uniprot id: W5QAK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

9940:SERPINA1
gene id: 9940:SERPINA1
uniprot id: P12725
uniprot id: W5PZS7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the serpin family.
messages: Inhibits human leukocyte elastase, pig pancreatic elastase and bovine trypsin on a 1:1 molar basis.
messages: Interacts with CELA2A (By similarity). Interacts with ERGIC3 and LMAN1/ERGIC53 (By similarity). Interacts with PRSS1/Trypsin (By similarity).
messages: Plasma.
messages: Secreted
messages: The reactive center loop (RCL) extends out from the body of the protein and directs binding to the target protease. The protease cleaves the serpin at the reactive site within the RCL, establishing a covalent linkage between the carboxyl group of the serpin reactive site and the serine hydroxyl of the protease. The resulting inactive serpin-protease complex is highly stable (By similarity).

9940:CSDC2
gene id: 9940:CSDC2
uniprot id: A0A836D4K2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL1B
gene id: 9940:IL1B
uniprot id: P21621
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. In its precursor form, weakly interacts with full-length MEFV; the mature cytokine does not interact at all. Interacts with integrins ITGAV:ITGBV and ITGA5:ITGB1; integrin-binding is required for IL1B signaling. Interacts with cargo receptor TMED10; the interaction is direct and is required for the secretion of IL1B mature form. Interacts with HSP90AB1; the interaction facilitates cargo translocation into the ERGIC. Interacts with HSP90B1; the interaction facilitates cargo translocation into the ERGIC.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

9940:CDC14B
gene id: 9940:CDC14B
uniprot id: W5PF48
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

9940:MED1
gene id: 9940:MED1
uniprot id: W5PN52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

9940:WARS1
gene id: 9940:WARS1
uniprot id: A0A835ZYM2
names: Caution
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SERPINA7
gene id: 9940:SERPINA7
uniprot id: P50450
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the serpin family.
messages: Expressed by the liver and secreted in plasma.
messages: Major thyroid hormone transport protein in serum.
messages: Secreted

9940:ERAP2
gene id: 9940:ERAP2
uniprot id: W5Q953
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9940:SERPINF2
gene id: 9940:SERPINF2
uniprot id: W5PXC8
names: Similarity
messages: Belongs to the serpin family.

9940:IFT20
gene id: 9940:IFT20
uniprot id: A0A836CZM6
uniprot id: W5Q7W7
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centriole
messages: cilium
messages: cis-Golgi network

9940:SREK1
gene id: 9940:SREK1
uniprot id: A0A6P3EB26
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSNK1G3
gene id: 9940:CSNK1G3
uniprot id: A0A6P7E3W1
uniprot id: W5QBQ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

9940:SLC25A11
gene id: 9940:SLC25A11
uniprot id: A0A6P9FRD0
uniprot id: B2MVX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAL1
gene id: 9940:DNAL1
uniprot id: A0A6P3E811
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBLN5
gene id: 9940:FBLN5
uniprot id: A0A6P3TB39
uniprot id: A0A6P7D2K1
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KPNA6
gene id: 9940:KPNA6
uniprot id: A0A6P3T9P0
names: Caution
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TOX4
gene id: 9940:TOX4
uniprot id: W5QEC6
names: Subcellular Location Annotation
messages: Nucleus

9940:HCLS1
gene id: 9940:HCLS1
uniprot id: A0A6P3E7W8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102682
gene id: 9940:LOC101102682
uniprot id: W5PKG9
names: Subcellular Location Annotation
messages: Membrane

9940:KIF5C
gene id: 9940:KIF5C
uniprot id: W5PIF0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:DYNC1I2
gene id: 9940:DYNC1I2
uniprot id: W5NUY8
uniprot id: W5NUZ1
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9940:NOP10
gene id: 9940:NOP10
uniprot id: W5QF48
names: Similarity
messages: Belongs to the NOP10 family.

9940:NAF1
gene id: 9940:NAF1
uniprot id: W5PW74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

9940:SLC35A4
gene id: 9940:SLC35A4
uniprot id: B2MVY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9940:MAB21L1
gene id: 9940:MAB21L1
uniprot id: W5P7V1
names: Similarity
messages: Belongs to the mab-21 family.

9940:MYO1B
gene id: 9940:MYO1B
uniprot id: W5PX99
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9940:DDI2
gene id: 9940:DDI2
uniprot id: W5PHE6
names: Similarity
messages: Belongs to the DDI1 family.

9940:LOC101113761
gene id: 9940:LOC101113761
uniprot id: A0A6P3E7H5
uniprot id: W5PSZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VMA21
gene id: 9940:VMA21
uniprot id: A0A6P3EN57
uniprot id: W5PG15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the V0 complex of the vacuolar ATPase (V-ATPase).
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103232
gene id: 9940:LOC101103232
uniprot id: W5Q496
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

9940:SFTPA1
gene id: 9940:SFTPA1
uniprot id: Q9TT06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SFTPA family.
messages: In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages.
messages: Oligomeric complex of 6 set of homotrimers.
messages: Secreted
messages: extracellular matrix
messages: surface film

9940:SLITRK4
gene id: 9940:SLITRK4
uniprot id: A0A6P3EN63
names: Similarity
messages: Belongs to the SLITRK family.

9940:CLCA2
gene id: 9940:CLCA2
uniprot id: W5PZ07
names: Similarity
messages: Belongs to the CLCR family.

9940:DPH3
gene id: 9940:DPH3
uniprot id: W5Q194
names: Similarity
messages: Belongs to the DPH3 family.

9940:QARS1
gene id: 9940:QARS1
uniprot id: A0A836A002
uniprot id: W5Q0S2
names: Caution
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BBS4
gene id: 9940:BBS4
uniprot id: A0A6P3EAR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome
messages: cilium membrane

9940:IZUMO2
gene id: 9940:IZUMO2
uniprot id: A0A0M5KTR5
names: Similarity
messages: Belongs to the Izumo family.

9940:NELFE
gene id: 9940:NELFE
uniprot id: A0A835ZVB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NELF-E family.
messages: Chromosome
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPS4
gene id: 9940:COPS4
uniprot id: A0A6P3EFB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle
messages: synaptic vesicle

9940:K38
gene id: 9940:K38
uniprot id: B0LKP2
names: Similarity
messages: Belongs to the intermediate filament family.

9940:OTUB2
gene id: 9940:OTUB2
uniprot id: A0A6P3T2N3
names: Caution
names: Similarity
messages: Belongs to the peptidase C65 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCEE
gene id: 9940:MCEE
uniprot id: W5Q336
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

9940:BCL2L15
gene id: 9940:BCL2L15
uniprot id: A0A6P3DYR4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SBDS
gene id: 9940:SBDS
uniprot id: A0A6P3EGH3
uniprot id: W5PLQ9
names: Caution
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RETN
gene id: 9940:RETN
uniprot id: A0A6P3CY62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistin/FIZZ family.
messages: Secreted

9940:HBB
gene id: 9940:HBB
uniprot id: Q1KYZ7
names: Similarity
messages: Belongs to the globin family.

9940:UGT1A6
gene id: 9940:UGT1A6
uniprot id: F1CGW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:THEMIS
gene id: 9940:THEMIS
uniprot id: W5PVH7
names: Similarity
messages: Belongs to the themis family.

9940:PSMD6
gene id: 9940:PSMD6
uniprot id: W5PNT5
names: Similarity
messages: Belongs to the proteasome subunit S10 family.

9940:S1PR3
gene id: 9940:S1PR3
uniprot id: A0A6P3E0J1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FTSJ1
gene id: 9940:FTSJ1
uniprot id: A0A6P3TFP6
uniprot id: A0A6P3THP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHN2
gene id: 9940:CHN2
uniprot id: A0A6P3E447
uniprot id: W5PGJ4
names: Caution
names: Function
messages: GTPase-activating protein for p21-rac.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZIC5
gene id: 9940:ZIC5
uniprot id: W5P2P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

9940:LOC101118006
gene id: 9940:LOC101118006
uniprot id: A0A836D430
uniprot id: W5QA06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUCNR1
gene id: 9940:SUCNR1
uniprot id: A0A6P3TI98
uniprot id: W5P0P6
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MSTN
gene id: 9940:MSTN
uniprot id: A0A0A0YQ60
uniprot id: O18830
uniprot id: Q19BJ5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted
messages: Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase.

9940:UROD
gene id: 9940:UROD
uniprot id: A0A836D7U0
uniprot id: Q8HY31
names: Caution
names: Disease Annotation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway. Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme. In vitro also decarboxylates pentacarboxylate porphyrinogen I.
messages: Cytoplasm
messages: Defects in UROD are the cause of porphyria cutanea tarda (PCT). PCT has been identified in a flock of German Blackface sheep. It is characterized by photosensitivity and porphyrinuria.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC443326
gene id: 9940:LOC443326
uniprot id: A0A6P3E9E9
uniprot id: W5PQI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SF3B5
gene id: 9940:SF3B5
uniprot id: W5NX84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

9940:ARF4
gene id: 9940:ARF4
uniprot id: C5IWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9940:OSTN
gene id: 9940:OSTN
uniprot id: A0A6P3E6V0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNAI2
gene id: 9940:SNAI2
uniprot id: A0A6P3CWW7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM35A
gene id: 9940:TMEM35A
uniprot id: A0A6P3EHL5
uniprot id: W5NT54
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle

9940:TVP23A
gene id: 9940:TVP23A
uniprot id: A0A6P3EQP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAS
gene id: 9940:FAS
uniprot id: O97491
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane raft

9940:PLSCR5
gene id: 9940:PLSCR5
uniprot id: W5P665
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9940:KEF53 p09
gene id: 9940:KEF53_p09
uniprot id: O78751
uniprot id: Q5MA73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with PRICKLE3 (By similarity).
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion membrane

9940:CCR9
gene id: 9940:CCR9
uniprot id: Q1WLP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level (By similarity).

9940:MT4
gene id: 9940:MT4
uniprot id: A6YLP3
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals.

9940:CCSER1
gene id: 9940:CCSER1
uniprot id: W5QAE6
names: Similarity
messages: Belongs to the CCSER family.

9940:SCML2
gene id: 9940:SCML2
uniprot id: A0A6P3YPP3
uniprot id: W5PW11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NAA35
gene id: 9940:NAA35
uniprot id: A0A6P7DN39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Auxillary component of the N-terminal acetyltransferase C (NatC) complex which catalyzes acetylation of N-terminal methionine residues. Involved in regulation of apoptosis and proliferation of smooth muscle cells.
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

9940:TNNI3
gene id: 9940:TNNI3
uniprot id: A0A6P3ECI8
uniprot id: W5NUQ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the troponin I family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9940:GGCX
gene id: 9940:GGCX
uniprot id: Q9GL59
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the vitamin K-dependent gamma-carboxylase family.
messages: Endoplasmic reticulum membrane
messages: Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
messages: Monomer (By similarity). May interact with CALU (By similarity).
messages: The vitamin K-dependent protein substrates of carboxylase have usually a propeptide that binds to a high-affinity site on the carboxylase. CO(2), O(2) and reduced vitamin K are cosubstrates.

9940:FKBP14
gene id: 9940:FKBP14
uniprot id: A0A6P3E4Z0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC42SE1
gene id: 9940:CDC42SE1
uniprot id: A0A6P7EJV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

9940:LOC101116313
gene id: 9940:LOC101116313
uniprot id: A0A836AG91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN10
gene id: 9940:CLDN10
uniprot id: A0A6P3E9H3
uniprot id: W5NVE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:HOXA6
gene id: 9940:HOXA6
uniprot id: A0A6P3E4Z6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYO5A
gene id: 9940:MYO5A
uniprot id: A0A6P3YIX4
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUTM1
gene id: 9940:NUTM1
uniprot id: W5QF46
names: Similarity
messages: Belongs to the NUT family.

9940:RNF41
gene id: 9940:RNF41
uniprot id: A0A6P3E3C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPGS2
gene id: 9940:TPGS2
uniprot id: A0A6P3EQE4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL22
gene id: 9940:MRPL22
uniprot id: A0A836A4C7
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALAS1
gene id: 9940:ALAS1
uniprot id: A0A6P3EN82
uniprot id: W5P896
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MFSD5
gene id: 9940:MFSD5
uniprot id: A0A6P3EBH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Cell membrane
messages: Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTGER2
gene id: 9940:PTGER2
uniprot id: W5Q8C2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:WNT2B
gene id: 9940:WNT2B
uniprot id: A0A6P3E5I8
uniprot id: W5QEJ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:PTX3
gene id: 9940:PTX3
uniprot id: A0A836D7N7
uniprot id: W5NXM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LYVE1
gene id: 9940:LYVE1
uniprot id: A0A836CVZ7
uniprot id: W5PN42
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NODAL
gene id: 9940:NODAL
uniprot id: W5P7U5
names: Similarity
messages: Belongs to the TGF-beta family.

9940:CRABP2
gene id: 9940:CRABP2
uniprot id: W5P895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9940:LOC101105866
gene id: 9940:LOC101105866
uniprot id: A0A6P3YS77
uniprot id: W5Q1H2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112694
gene id: 9940:LOC101112694
uniprot id: A0A6P3EQU2
uniprot id: W5NY25
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPUSD1
gene id: 9940:RPUSD1
uniprot id: A0A6P3YP87
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NME4
gene id: 9940:NME4
uniprot id: A0A6P3EG59
names: Caution
names: Similarity
messages: Belongs to the NDK family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INTS12
gene id: 9940:INTS12
uniprot id: A0A6P3TT46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

9940:ZNF664
gene id: 9940:ZNF664
uniprot id: A0A6P7CZX6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A10
gene id: 9940:SLC39A10
uniprot id: W5PY59
names: Subcellular Location Annotation
messages: Membrane

9940:VPS13B
gene id: 9940:VPS13B
uniprot id: W5NWA2
names: Similarity
messages: Belongs to the VPS13 family.

9940:BCO1
gene id: 9940:BCO1
uniprot id: C7C6F6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9940:CWF19L2
gene id: 9940:CWF19L2
uniprot id: W5PK08
names: Similarity
messages: Belongs to the CWF19 family.

9940:POU1F1
gene id: 9940:POU1F1
uniprot id: P79364
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Interacts with PITX1. Interacts with LHX3. Interacts with ELK1.
messages: Nucleus
messages: The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
messages: Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Activates growth hormone and prolactin genes. Specifically binds to the consensus sequence 5'-TAAAT-3'.

9940:CCND3
gene id: 9940:CCND3
uniprot id: A0A6P9FQE6
uniprot id: B2MVY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLCN6
gene id: 9940:CLCN6
uniprot id: W5QA97
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:LOC101110587
gene id: 9940:LOC101110587
uniprot id: W5PRB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CCL22
gene id: 9940:CCL22
uniprot id: W5NPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9940:LOC101107990
gene id: 9940:LOC101107990
uniprot id: W5P8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:DOCK10
gene id: 9940:DOCK10
uniprot id: A0A6P3E6L7
uniprot id: W5QGV5
names: Caution
names: Similarity
messages: Belongs to the DOCK family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121639
gene id: 9940:LOC101121639
uniprot id: A0A836D6H0
names: Caution
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNU13
gene id: 9940:SNU13
uniprot id: A0A6P3EBG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9940:CCKBR
gene id: 9940:CCKBR
uniprot id: W5QBM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:IL2RA
gene id: 9940:IL2RA
uniprot id: P26898
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit (By similarity).
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

9940:P2RX1
gene id: 9940:P2RX1
uniprot id: W5Q906
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9940:OSBPL11
gene id: 9940:OSBPL11
uniprot id: A0A6P3E4Y9
uniprot id: W5QG92
names: Caution
names: Similarity
messages: Belongs to the OSBP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIGL
gene id: 9940:PIGL
uniprot id: W5Q6F8
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

9940:LOC101119842
gene id: 9940:LOC101119842
uniprot id: A0A6P3EJU9
uniprot id: W5PPC0
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AHCYL2
gene id: 9940:AHCYL2
uniprot id: W5P2N4
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9940:LOC101114310
gene id: 9940:LOC101114310
uniprot id: W5Q0L5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

9940:LOC101117285
gene id: 9940:LOC101117285
uniprot id: W5P7N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: Cytoplasm
messages: Interacts with PEX5; the interaction is essential for peroxisomal import.
messages: Mitochondrion
messages: Peroxisome

9940:SMC1A
gene id: 9940:SMC1A
uniprot id: W5PFJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

9940:UBE2R2
gene id: 9940:UBE2R2
uniprot id: W5PHW1
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:GTF2F1
gene id: 9940:GTF2F1
uniprot id: A0A6P3EDP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ASRGL1
gene id: 9940:ASRGL1
uniprot id: A0A835ZXD8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the Ntn-hydrolase family.
messages: Heterodimer of an alpha and beta chain produced by autocleavage. This heterodimer may then dimerize in turn, giving rise to a heterotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPPB
gene id: 9940:NPPB
uniprot id: O46541
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Cardiac hormone that plays a key role in mediating cardio-renal homeostasis (By similarity). May also function as a paracrine antifibrotic factor in the heart (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins that drive various biological responses. Involved in regulating the extracellular fluid volume and maintaining the fluid-electrolyte balance through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Binds the clearance receptor NPR3 (By similarity).
messages: Secreted
messages: The precursor molecule is proteolytically cleaved, possibly by FURIN or CORIN, to produce the active peptide (By similarity). May undergo further proteolytic cleavage by various proteases such as DPP4, MME and possibly FAP, to give rise to a variety of shorter peptides (By similarity). May be cleaved at Pro-99 by the prolyl endopeptidase FAP (seprase) activity (in vitro) (By similarity). May be degraded by IDE (By similarity). During IDE degradation, the resulting products initially increase the activation of NPR1 and can also stimulate NPR2 to produce cGMP before the fragments are completely degraded and inactivated by IDE (in vitro) (By similarity).

9940:GADD45G
gene id: 9940:GADD45G
uniprot id: W5PD38
names: Similarity
messages: Belongs to the GADD45 family.

9940:EIF4E
gene id: 9940:EIF4E
uniprot id: W5Q2Y8
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

9940:SPARCL1
gene id: 9940:SPARCL1
uniprot id: W5P4K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

9940:KRTAP5.4
gene id: 9940:KRTAP5.4
uniprot id: Q28583
names: Function
messages: The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).

9940:KIF1B
gene id: 9940:KIF1B
uniprot id: W5P700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

9940:CTSK
gene id: 9940:CTSK
uniprot id: W5QI78
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Cell membrane
messages: Lysosome
messages: Secreted

9940:PIGU
gene id: 9940:PIGU
uniprot id: W5PK54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:HSPA5
gene id: 9940:HSPA5
uniprot id: A0A6P3EAN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EMCN
gene id: 9940:EMCN
uniprot id: A0A6P3E5A8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM76A
gene id: 9940:FAM76A
uniprot id: A0A836D5Z7
uniprot id: W5NZE4
names: Caution
names: Similarity
messages: Belongs to the FAM76 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105601856
gene id: 9940:LOC105601856
uniprot id: A0A836A6L4
uniprot id: W5Q5N7
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOC2L
gene id: 9940:NOC2L
uniprot id: A0A6P3TIU6
uniprot id: W5PDH8
names: Caution
names: Similarity
messages: Belongs to the NOC2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NEU3
gene id: 9940:NEU3
uniprot id: A0A6P3ED51
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM144
gene id: 9940:TMEM144
uniprot id: A0A6P3ENK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM144 family.
messages: Membrane

9940:RASSF8
gene id: 9940:RASSF8
uniprot id: A0A6P3TKB9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC106990414
gene id: 9940:LOC106990414
uniprot id: A0A835ZN36
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102057
gene id: 9940:LOC101102057
uniprot id: A0A6P3E5L6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111440
gene id: 9940:LOC101111440
uniprot id: W5Q6G0
names: Similarity
messages: Belongs to the intermediate filament family.

9940:UBAP2L
gene id: 9940:UBAP2L
uniprot id: A0A6P3TJ82
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTGR1
gene id: 9940:PTGR1
uniprot id: A0A6P3TGH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

9940:PRDX2
gene id: 9940:PRDX2
uniprot id: A0A6P7E1M0
uniprot id: C8BKC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9940:FAM209A
gene id: 9940:FAM209A
uniprot id: A0A6P3E989
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYBB
gene id: 9940:CYBB
uniprot id: A0A6P3ERU7
uniprot id: W5QC99
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OLFML2B
gene id: 9940:OLFML2B
uniprot id: W5PLG3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:HADHB
gene id: 9940:HADHB
uniprot id: A0A6P3E9R6
uniprot id: A0A6P7DVD9
names: Caution
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL30
gene id: 9940:MRPL30
uniprot id: A0A6P3E2U3
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9940:MED18
gene id: 9940:MED18
uniprot id: A0A6P3E6P5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9940:ATR
gene id: 9940:ATR
uniprot id: A0A836AHY6
names: Caution
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPRY4
gene id: 9940:SPRY4
uniprot id: A0A6P7E1U3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDFY1
gene id: 9940:WDFY1
uniprot id: W5QGR5
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9940:TCTA
gene id: 9940:TCTA
uniprot id: A0A6P3ECB3
uniprot id: W5PWG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: May be required for cellular fusion during osteoclastogenesis.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BMP15
gene id: 9940:BMP15
uniprot id: A0A0S1TT01
uniprot id: A0A835ZFN4
uniprot id: Q9MZE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer (By similarity). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth (By similarity).
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTGR2
gene id: 9940:PTGR2
uniprot id: A0A6P3EFF2
uniprot id: W5NRG0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TEKT5
gene id: 9940:TEKT5
uniprot id: A0A6P3ERG0
uniprot id: W5P758
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: flagellum

9940:SEC23A
gene id: 9940:SEC23A
uniprot id: A0A6P3EEB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:LOC101108086
gene id: 9940:LOC101108086
uniprot id: A0A6P3EJI1
uniprot id: A0A836CTR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYP19
gene id: 9940:CYP19
uniprot id: Q9XS28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
messages: Membrane

9940:TNPO1
gene id: 9940:TNPO1
uniprot id: A0A6P3EDL1
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MBD4
gene id: 9940:MBD4
uniprot id: W5PZ82
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

9940:CENPK
gene id: 9940:CENPK
uniprot id: A0A6P3EN89
uniprot id: A0A6P3YN62
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-K/MCM22 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centromere

9940:MGME1
gene id: 9940:MGME1
uniprot id: A0A836CWE3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPB11
gene id: 9940:HSPB11
uniprot id: A0A6P3E402
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108746
gene id: 9940:LOC101108746
uniprot id: W5Q5R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:STAMBPL1
gene id: 9940:STAMBPL1
uniprot id: A0A6P3EPW9
uniprot id: A0A6P3TIQ4
names: Caution
names: Similarity
messages: Belongs to the peptidase M67C family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUDT2
gene id: 9940:NUDT2
uniprot id: A0A836ALY5
uniprot id: W5PHQ4
names: Caution
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MINDY3
gene id: 9940:MINDY3
uniprot id: W5PG92
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

9940:UMOD
gene id: 9940:UMOD
uniprot id: W5PSM9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Cell membrane
messages: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium membrane

9940:SLC7A9
gene id: 9940:SLC7A9
uniprot id: A0A6P3EL78
uniprot id: A0A6P7EVW1
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HCAR2
gene id: 9940:HCAR2
uniprot id: W5P3D9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:TMEM156
gene id: 9940:TMEM156
uniprot id: A0A836D0Q1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WFIKKN2
gene id: 9940:WFIKKN2
uniprot id: W5NZ88
names: Similarity
messages: Belongs to the WFIKKN family.

9940:COPS7A
gene id: 9940:COPS7A
uniprot id: A0A6P3TKJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

9940:PDE1A
gene id: 9940:PDE1A
uniprot id: W5Q5R0
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9940:AQP9
gene id: 9940:AQP9
uniprot id: A0A6P3EF22
uniprot id: W5QI67
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRIM4
gene id: 9940:TRIM4
uniprot id: A0A6P3ELX8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109747
gene id: 9940:LOC101109747
uniprot id: A0A6P3T7R2
uniprot id: B8ZY39
names: Caution
names: Similarity
messages: Belongs to the MHC class II family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ME2
gene id: 9940:ME2
uniprot id: W5P368
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9940:LOC101110385
gene id: 9940:LOC101110385
uniprot id: W5PXQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

9940:ERBIN
gene id: 9940:ERBIN
uniprot id: A0A836CVI0
uniprot id: W5P7P9
names: Caution
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GJB5
gene id: 9940:GJB5
uniprot id: W5NQF5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: gap junction

9940:LY6G6C
gene id: 9940:LY6G6C
uniprot id: A0A6P3ECQ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GTPBP3
gene id: 9940:GTPBP3
uniprot id: W5Q668
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

9940:HTR1D
gene id: 9940:HTR1D
uniprot id: W5QAN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1B.
messages: Membrane

9940:IDH3B
gene id: 9940:IDH3B
uniprot id: W5P8N8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9940:RAB11A
gene id: 9940:RAB11A
uniprot id: A0A6P3E779
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108337
gene id: 9940:LOC101108337
uniprot id: W5Q762
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC654403
gene id: 9940:LOC654403
uniprot id: A0A6P3E708
uniprot id: W5QHK1
names: Caution
names: Similarity
messages: Belongs to the arrestin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTIF2
gene id: 9940:MTIF2
uniprot id: A0A6P3E2M6
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

9940:NIFK
gene id: 9940:NIFK
uniprot id: A0A6P3YHV2
uniprot id: W5PV04
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:SERPINB1
gene id: 9940:SERPINB1
uniprot id: D8X187
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9940:SLC25A26
gene id: 9940:SLC25A26
uniprot id: B2MVX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:KLHL41
gene id: 9940:KLHL41
uniprot id: A0A836D6Y7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPB2
gene id: 9940:COPB2
uniprot id: A0A6P3E8E1
uniprot id: W5PAX6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

9940:LOC101121908
gene id: 9940:LOC101121908
uniprot id: W5NQE7
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9940:CYP11A1
gene id: 9940:CYP11A1
uniprot id: P79202
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones (By similarity). Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal (By similarity). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin) (By similarity).
messages: Belongs to the cytochrome P450 family.
messages: Interacts with FDX1/adrenodoxin.
messages: Mitochondrion inner membrane

9940:APH1A
gene id: 9940:APH1A
uniprot id: A0A6P3E5Q3
uniprot id: W5QHY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAF7L
gene id: 9940:TAF7L
uniprot id: W5NTU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9940:LOC101112513
gene id: 9940:LOC101112513
uniprot id: A0A835ZTL8
uniprot id: W5PR30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYP17A1
gene id: 9940:CYP17A1
uniprot id: Q29497
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase involved in corticoid and androgen biosynthesis. Catalyzes 17-alpha hydroxylation of C21 steroids, which is common for both pathways. A second oxidative step, required only for androgen synthesis, involves an acyl-carbon cleavage. The 17-alpha hydroxy intermediates, as part of adrenal glucocorticoids biosynthesis pathway, are precursors of cortisol. Hydroxylates steroid hormones, pregnenolone and progesterone to form 17-alpha hydroxy metabolites, followed by the cleavage of the C17-C20 bond to form C19 steroids, dehydroepiandrosterone (DHEA) and androstenedione. Has 16-alpha hydroxylase activity. Catalyzes 16-alpha hydroxylation of 17-alpha hydroxy pregnenolone, followed by the cleavage of the C17-C20 bond to form 16-alpha-hydroxy DHEA. Also 16-alpha hydroxylates androgens, relevant for estriol synthesis. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane
messages: Regulated predominantly by intracellular cAMP levels. The 17,20-lyase activity is stimulated by cytochrome b5, which acts as an allosteric effector increasing the Vmax of the lyase activity.

9940:CPO
gene id: 9940:CPO
uniprot id: W5QBY3
names: Similarity
messages: Belongs to the peptidase M14 family.

9940:SLC25A29
gene id: 9940:SLC25A29
uniprot id: W5NUR9
uniprot id: W5NUS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:HDC
gene id: 9940:HDC
uniprot id: W5QIK7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9940:AK1
gene id: 9940:AK1
uniprot id: A0A6P9FQJ4
uniprot id: C5IJA8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK1 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRPM7
gene id: 9940:TRPM7
uniprot id: A4ZVC4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.
messages: Membrane

9940:PLK2
gene id: 9940:PLK2
uniprot id: A0A6P3EB43
uniprot id: W5PBE3
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V0A4
gene id: 9940:ATP6V0A4
uniprot id: W5PLB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

9940:NDUFB7
gene id: 9940:NDUFB7
uniprot id: A0A8N7XJH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB7 subunit family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAX6
gene id: 9940:PAX6
uniprot id: W5Q3U7
uniprot id: W5Q3U9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:BAZ2A
gene id: 9940:BAZ2A
uniprot id: A0A6P3E3B4
names: Caution
names: Similarity
messages: Belongs to the WAL family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM154
gene id: 9940:TMEM154
uniprot id: A0A6P9FR30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CATHL3
gene id: 9940:CATHL3
uniprot id: P50415
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms (By similarity).
messages: Secreted

9940:NGB
gene id: 9940:NGB
uniprot id: A0A6P3EFG7
uniprot id: W5NWE8
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103669
gene id: 9940:LOC101103669
uniprot id: W5PBH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:FANCM
gene id: 9940:FANCM
uniprot id: W5PI59
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.

9940:POLR2I
gene id: 9940:POLR2I
uniprot id: A0A6P3EFK6
uniprot id: W5P5E8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:CLDN15
gene id: 9940:CLDN15
uniprot id: A0A6P3T9Z0
uniprot id: A0A6P3TJV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:ABRAXAS1
gene id: 9940:ABRAXAS1
uniprot id: A0A6P3YM19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB8
gene id: 9940:PSMB8
uniprot id: B3VSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9940:PDCD5
gene id: 9940:PDCD5
uniprot id: W5P225
names: Similarity
messages: Belongs to the PDCD5 family.

9940:MAP4
gene id: 9940:MAP4
uniprot id: W5NXB5
names: Subcellular Location Annotation
messages: cytoskeleton

9940:DNTTIP1
gene id: 9940:DNTTIP1
uniprot id: A0A6P3EF48
uniprot id: W5P8P6
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MILR1
gene id: 9940:MILR1
uniprot id: A0A6P3EAJ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ETS2
gene id: 9940:ETS2
uniprot id: W5PYQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9940:GLIS3
gene id: 9940:GLIS3
uniprot id: W5PV59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

9940:MLANA
gene id: 9940:MLANA
uniprot id: A0A6P3YG15
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107496
gene id: 9940:LOC101107496
uniprot id: A0A6P3YII5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114419
gene id: 9940:LOC101114419
uniprot id: A0A6P3T6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

9940:CCT6B
gene id: 9940:CCT6B
uniprot id: W5PFI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9940:LOC106990148
gene id: 9940:LOC106990148
uniprot id: W5P1T3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9940:MFAP1
gene id: 9940:MFAP1
uniprot id: A0A6P3EEC0
uniprot id: W5PNL1
names: Caution
names: Function
names: Similarity
messages: Belongs to the MFAP1 family.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADAT2
gene id: 9940:ADAT2
uniprot id: W5NTV4
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family. ADAT2 subfamily.
messages: Probably participates in deamination of adenosine-34 to inosine in many tRNAs.

9940:DHRS7C
gene id: 9940:DHRS7C
uniprot id: W5NZC0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:PARP14
gene id: 9940:PARP14
uniprot id: W5QG00
names: Similarity
messages: Belongs to the ARTD/PARP family.

9940:ST3GAL3
gene id: 9940:ST3GAL3
uniprot id: A0A6P3YGJ2
uniprot id: W5NQT4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX21
gene id: 9940:DDX21
uniprot id: A0A6P9FQV3
uniprot id: W5P5J5
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIPE
gene id: 9940:LIPE
uniprot id: B3EYB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: Cell membrane
messages: Lipid droplet
messages: caveola
messages: cytosol

9940:LOC101122647
gene id: 9940:LOC101122647
uniprot id: A0A6P3TIU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAB3
gene id: 9940:TAB3
uniprot id: A0A6P3YQ43
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNYL1
gene id: 9940:CCNYL1
uniprot id: W5QC45
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9940:LPAR6
gene id: 9940:LPAR6
uniprot id: S4TZP1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:LOC101121351
gene id: 9940:LOC101121351
uniprot id: A0A836AEA7
uniprot id: W5NRF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ELOVL3
gene id: 9940:ELOVL3
uniprot id: W5Q848
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL3 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9940:EIF5A
gene id: 9940:EIF5A
uniprot id: A0A6P3TWD0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

9940:GNS
gene id: 9940:GNS
uniprot id: W5NZ62
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9940:SIAH1
gene id: 9940:SIAH1
uniprot id: W5Q641
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9940:TM4SF18
gene id: 9940:TM4SF18
uniprot id: A0A6P3E8C5
uniprot id: W5P4A7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSNK2B
gene id: 9940:CSNK2B
uniprot id: B7U170
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

9940:SDE2
gene id: 9940:SDE2
uniprot id: A0A6P3EHY7
uniprot id: W5Q8U6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDE2 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIAS1
gene id: 9940:PIAS1
uniprot id: A0A6P3YMH9
names: Caution
names: Similarity
messages: Belongs to the PIAS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123223
gene id: 9940:LOC101123223
uniprot id: A0A6P3EIE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GUCA1B
gene id: 9940:GUCA1B
uniprot id: A0A835ZSL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CREB1
gene id: 9940:CREB1
uniprot id: A0A6P3EA07
uniprot id: W5QBZ9
names: Subcellular Location Annotation
messages: Nucleus

9940:TCEAL1
gene id: 9940:TCEAL1
uniprot id: W5PJP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family. TFA subfamily.
messages: Nucleus

9940:STK32B
gene id: 9940:STK32B
uniprot id: W5PB90
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:RAB5A
gene id: 9940:RAB5A
uniprot id: A0A6P3YEQ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRP2
gene id: 9940:PRP2
uniprot id: A8QW38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9940:ABHD14A
gene id: 9940:ABHD14A
uniprot id: A0A6P3EN85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLT1D1
gene id: 9940:GLT1D1
uniprot id: A0A6P3EDX9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104781
gene id: 9940:LOC101104781
uniprot id: A0A836CV55
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AMH
gene id: 9940:AMH
uniprot id: T1SHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression.
messages: Secreted

9940:TAFAZZIN
gene id: 9940:TAFAZZIN
uniprot id: A0A6P3EN53
uniprot id: W5P447
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acyltransferase which is required to remodel newly synthesized phospholipid cardiolipin, a key component of the mitochondrial inner membrane. Required for the initiation of mitophagy. Required to ensure progression of spermatocytes through meiosis.
messages: Associates with multiple protein complexes.
messages: Belongs to the taffazin family.
messages: Mitochondrion inner membrane
messages: Mitochondrion outer membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122880
gene id: 9940:LOC101122880
uniprot id: A0A6P3EL04
uniprot id: W5QCB7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPO
gene id: 9940:EPO
uniprot id: P33709
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the EPO/TPO family.
messages: Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3.
messages: Produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals.
messages: Secreted

9940:CTSB
gene id: 9940:CTSB
uniprot id: P83205
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Dimer of a heavy chain and a light chain cross-linked by a disulfide bond. Interacts with SRPX2. Directly interacts with SHKBP1.
messages: Lysosome
messages: Melanosome
messages: Thiol protease which is believed to participate in intracellular degradation and turnover of proteins (By similarity). Cleaves matrix extracellular phosphoglycoprotein MEPE (By similarity). Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen (By similarity). Has also been implicated in tumor invasion and metastasis (By similarity).
messages: extracellular space

9940:LOC101102694
gene id: 9940:LOC101102694
uniprot id: A0A6P3E3R3
uniprot id: W5Q9L6
names: Similarity
messages: Belongs to the mTERF family.

9940:RDH12
gene id: 9940:RDH12
uniprot id: A0A6P3EBC3
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121084
gene id: 9940:LOC101121084
uniprot id: A0A6P3E3Q2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANAPC11
gene id: 9940:ANAPC11
uniprot id: A0A6P3E8A5
uniprot id: A0A6P7EFS1
names: Caution
names: Similarity
messages: Belongs to the RING-box family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DIRAS3
gene id: 9940:DIRAS3
uniprot id: A0A6P3TFY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSTF2T
gene id: 9940:CSTF2T
uniprot id: W5QCU3
names: Subcellular Location Annotation
messages: Nucleus

9940:MXD1
gene id: 9940:MXD1
uniprot id: A0A6P3EAU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120814
gene id: 9940:LOC101120814
uniprot id: A0A6P3EHQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRNA2
gene id: 9940:CHRNA2
uniprot id: W5PIW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:CALY
gene id: 9940:CALY
uniprot id: W5NRQ2
names: Similarity
messages: Belongs to the NSG family.

9940:ASF1A
gene id: 9940:ASF1A
uniprot id: C8BKD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

9940:GTPBP4
gene id: 9940:GTPBP4
uniprot id: A0A836A3P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:RHO
gene id: 9940:RHO
uniprot id: W5PXZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9940:GPR160
gene id: 9940:GPR160
uniprot id: A0A6P3T2W0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IMPDH2
gene id: 9940:IMPDH2
uniprot id: A0A6P3EIU2
uniprot id: W5Q1I6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EARS2
gene id: 9940:EARS2
uniprot id: W5Q6N0
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

9940:FLOT1
gene id: 9940:FLOT1
uniprot id: A0A836CTM6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: caveola

9940:PHAF1
gene id: 9940:PHAF1
uniprot id: A0A836A0Q6
uniprot id: W5NXG6
names: Caution
names: Similarity
messages: Belongs to the PHAF1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPS7B
gene id: 9940:COPS7B
uniprot id: A0A6P7DLN1
uniprot id: C5ISA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS26C
gene id: 9940:VPS26C
uniprot id: A0A6P3E5D1
uniprot id: W5PY43
names: Caution
names: Similarity
messages: Belongs to the VPS26 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SERPINC1
gene id: 9940:SERPINC1
uniprot id: P32262
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).
messages: Phosphorylated by FAM20C in the extracellular medium.
messages: Plasma.
messages: extracellular space

9940:RGS8
gene id: 9940:RGS8
uniprot id: A0A6P7EKT9
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: Perikaryon
messages: dendrite

9940:ADRM1
gene id: 9940:ADRM1
uniprot id: W5PXE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

9940:MCUB
gene id: 9940:MCUB
uniprot id: A0A6P3EDM3
uniprot id: W5P7S5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RTN4IP1
gene id: 9940:RTN4IP1
uniprot id: W5PNA6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9940:MBNL1
gene id: 9940:MBNL1
uniprot id: A0A6P3TI85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DHDDS
gene id: 9940:DHDDS
uniprot id: W5P315
names: Similarity
messages: Belongs to the UPP synthase family.

9940:POF1B
gene id: 9940:POF1B
uniprot id: A0A835ZN88
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GAPVD1
gene id: 9940:GAPVD1
uniprot id: A0A6P3TAB9
uniprot id: W5PTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

9940:HPD
gene id: 9940:HPD
uniprot id: A0A6P3EBH2
uniprot id: W5PSL9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THPO
gene id: 9940:THPO
uniprot id: W5QHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPO/TPO family.
messages: Secreted

9940:ACMSD
gene id: 9940:ACMSD
uniprot id: W5PNY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

9940:SMG1
gene id: 9940:SMG1
uniprot id: W5PMR0
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

9940:CSTF1
gene id: 9940:CSTF1
uniprot id: A0A6P3EEY4
uniprot id: W5QAA0
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A25
gene id: 9940:SLC25A25
uniprot id: W5PMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9940:HYAL3
gene id: 9940:HYAL3
uniprot id: W5PJ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

9940:LOC101109935
gene id: 9940:LOC101109935
uniprot id: A0A836CTN2
uniprot id: W5PD13
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NTMT2
gene id: 9940:NTMT2
uniprot id: A0A836CYF4
names: Caution
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GALM
gene id: 9940:GALM
uniprot id: A0A6P3E2P2
uniprot id: W5PGC5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANXA9
gene id: 9940:ANXA9
uniprot id: A0A6P3TFC2
uniprot id: A0A6P7EJP0
names: Caution
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NFYA
gene id: 9940:NFYA
uniprot id: A0A6P3EPR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AZU1
gene id: 9940:AZU1
uniprot id: A0A836D5N0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLCA1
gene id: 9940:CLCA1
uniprot id: W5PZ44
names: Similarity
messages: Belongs to the CLCR family.

9940:RAF1
gene id: 9940:RAF1
uniprot id: W5Q234
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9940:TM7SF3
gene id: 9940:TM7SF3
uniprot id: W5QEZ2
names: Subcellular Location Annotation
messages: Membrane

9940:FMO5
gene id: 9940:FMO5
uniprot id: A0A6P3E6Z5
uniprot id: A0A6P3TMZ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKCE
gene id: 9940:PRKCE
uniprot id: A0A6P3E2N3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton
messages: perinuclear region

9940:CORO1A
gene id: 9940:CORO1A
uniprot id: A0A6P3TEE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat coronin family.
messages: Binds actin.
messages: Membrane
messages: cell cortex
messages: cytoskeleton
messages: phagosome membrane

9940:CDC37L1
gene id: 9940:CDC37L1
uniprot id: A0A6P3E9B6
uniprot id: W5PVC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113369
gene id: 9940:LOC101113369
uniprot id: A0A836CVN3
uniprot id: W5QGB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB27B
gene id: 9940:RAB27B
uniprot id: W5P4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9940:FGG
gene id: 9940:FGG
uniprot id: W5Q5A6
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9940:NAA40
gene id: 9940:NAA40
uniprot id: W5P1I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA40 subfamily.
messages: Cytoplasm
messages: Nucleus

9940:CREBL2
gene id: 9940:CREBL2
uniprot id: A0A6P3EB82
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HMGCS1
gene id: 9940:HMGCS1
uniprot id: A0A6P3T5V7
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9940:LOC101118521
gene id: 9940:LOC101118521
uniprot id: W5QAI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC100240716
gene id: 9940:LOC100240716
uniprot id: A0A6P9FQJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

9940:DDX10
gene id: 9940:DDX10
uniprot id: A0A6P3EA57
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3C
gene id: 9940:POLR3C
uniprot id: A0A6P3E5N7
uniprot id: W5QHC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFB6
gene id: 9940:NDUFB6
uniprot id: D6QZ20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9940:PTPN2
gene id: 9940:PTPN2
uniprot id: A0A6P3YSQ3
names: Caution
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF3K
gene id: 9940:EIF3K
uniprot id: A0A6P3EFM4
uniprot id: W5P6X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit K family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with CCND3, but not with CCND1 and CCND2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGL
gene id: 9940:AGL
uniprot id: A0A6P3TG45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

9940:PRKAB1
gene id: 9940:PRKAB1
uniprot id: A0A6P3T1Z5
uniprot id: A0A6P3TAG1
names: Caution
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC37
gene id: 9940:CDC37
uniprot id: A0A6P3E4I2
uniprot id: W5Q3Q7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDI1
gene id: 9940:GDI1
uniprot id: A0A6P9FRE2
uniprot id: C5IJ94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNF1B
gene id: 9940:HNF1B
uniprot id: W5NZG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9940:CSN3
gene id: 9940:CSN3
uniprot id: A0A059T9N6
uniprot id: P02669
names: Function
names: PTM
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the kappa-casein family.
messages: Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
messages: Mammary gland specific. Secreted in milk.
messages: O-glycosylated on Thr at position 156, 158 or 159.
messages: Secreted
messages: The frequency of variant Leu-125 is 0.015 in the Italian breed Sopravissana.

9940:LHX5
gene id: 9940:LHX5
uniprot id: W5PAX7
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101115671
gene id: 9940:LOC101115671
uniprot id: W5P0T3
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9940:RPL18
gene id: 9940:RPL18
uniprot id: A0A6P3EFU1
uniprot id: W5PQR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL18 family.
messages: Rough endoplasmic reticulum
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACER1
gene id: 9940:ACER1
uniprot id: A0A6P3ECM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ETFA
gene id: 9940:ETFA
uniprot id: A0A6P3EMP3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF1B
gene id: 9940:EIF1B
uniprot id: W5NX86
names: Similarity
messages: Belongs to the SUI1 family.

9940:TMEM223
gene id: 9940:TMEM223
uniprot id: A0A6P3EDA5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AACS
gene id: 9940:AACS
uniprot id: A0A6P3EM53
uniprot id: W5Q7T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:ZDHHC21
gene id: 9940:ZDHHC21
uniprot id: A0A6P3TGZ9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9940:THEM6
gene id: 9940:THEM6
uniprot id: A0A6P3EC50
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115849
gene id: 9940:LOC101115849
uniprot id: G9HPB5
uniprot id: G9HPB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9940:COQ2
gene id: 9940:COQ2
uniprot id: W5NW46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

9940:LOC101106121
gene id: 9940:LOC101106121
uniprot id: A0A6P3E695
names: Caution
names: Similarity
messages: Belongs to the cytochrome P450 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNMT
gene id: 9940:RNMT
uniprot id: A0A6P7EZF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus

9940:LRRC8E
gene id: 9940:LRRC8E
uniprot id: W5NY27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9940:CDC16
gene id: 9940:CDC16
uniprot id: A0A6P3YJX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX52
gene id: 9940:DDX52
uniprot id: W5NYE7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

9940:NAPSA
gene id: 9940:NAPSA
uniprot id: W5PWL7
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:XKRX
gene id: 9940:XKRX
uniprot id: A0A6P3YUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

9940:LOC101103772
gene id: 9940:LOC101103772
uniprot id: F5AY94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9940:PEBP1
gene id: 9940:PEBP1
uniprot id: A0A6P3EBI4
uniprot id: A0A6P7D8S1
names: Caution
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122362
gene id: 9940:LOC101122362
uniprot id: W5PVE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SLC43A3
gene id: 9940:SLC43A3
uniprot id: W5PHV7
names: Subcellular Location Annotation
messages: Membrane

9940:ENO2
gene id: 9940:ENO2
uniprot id: W5P5C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9940:ELOVL7
gene id: 9940:ELOVL7
uniprot id: W5PB15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9940:RAB11B
gene id: 9940:RAB11B
uniprot id: A0A6P3EDP1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AKAP9
gene id: 9940:AKAP9
uniprot id: W5Q6D6
names: Subcellular Location Annotation
messages: centrosome

9940:FGF22
gene id: 9940:FGF22
uniprot id: A0A836ACT3
names: Caution
names: Similarity
messages: Belongs to the heparin-binding growth factors family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35F5
gene id: 9940:SLC35F5
uniprot id: A0A6P3E1V1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TM9SF2
gene id: 9940:TM9SF2
uniprot id: A0A6P3E9H8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRR15L
gene id: 9940:PRR15L
uniprot id: A0A6P3E831
uniprot id: A0A6P3TL23
names: Caution
names: Similarity
messages: Belongs to the PRR15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM208
gene id: 9940:TMEM208
uniprot id: A0A6P3E9M2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PYROXD1
gene id: 9940:PYROXD1
uniprot id: W5QGM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

9940:SOSTDC1
gene id: 9940:SOSTDC1
uniprot id: A0A6P3E8R0
uniprot id: W5PF09
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPT1A
gene id: 9940:CPT1A
uniprot id: A0A6P3CWI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

9940:PNLIPRP3
gene id: 9940:PNLIPRP3
uniprot id: W5Q4J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9940:INHA
gene id: 9940:INHA
uniprot id: A0A0A0WFR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Dimeric, linked by one or more disulfide bonds. Inhibin A is a dimer of alpha and beta-A. Inhibin B is a dimer of alpha and beta-B.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition.
messages: Secreted

9940:EGR1
gene id: 9940:EGR1
uniprot id: B8QHP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

9940:CAPN1
gene id: 9940:CAPN1
uniprot id: B2ZA85
uniprot id: W5PVG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9940:GFER
gene id: 9940:GFER
uniprot id: A0A6P3ERE0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106825
gene id: 9940:LOC101106825
uniprot id: W5P185
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9940:GALK2
gene id: 9940:GALK2
uniprot id: W5QIM0
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9940:LOC101110266
gene id: 9940:LOC101110266
uniprot id: W5PRB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:TBL1XR1
gene id: 9940:TBL1XR1
uniprot id: A0A6P3TB26
names: Caution
names: Similarity
messages: Belongs to the WD repeat EBI family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VIP
gene id: 9940:VIP
uniprot id: B2KPH2
uniprot id: W5P198
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

9940:LGI1
gene id: 9940:LGI1
uniprot id: A0A6P3EFQ3
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLPP3
gene id: 9940:PLPP3
uniprot id: A0A6P3E6D0
uniprot id: W5PD88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM171B
gene id: 9940:FAM171B
uniprot id: W5Q525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9940:DCUN1D3
gene id: 9940:DCUN1D3
uniprot id: A0A6P3EQS1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC100526780
gene id: 9940:LOC100526780
uniprot id: E3VW85
names: Similarity
messages: Belongs to the intermediate filament family.

9940:FAM83A
gene id: 9940:FAM83A
uniprot id: A0A6P7EC35
uniprot id: W5PM83
names: Caution
names: Similarity
messages: Belongs to the FAM83 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAQR3
gene id: 9940:PAQR3
uniprot id: A0A6P3E5M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9940:ATP5MC2
gene id: 9940:ATP5MC2
uniprot id: A0A6P7DLH7
uniprot id: Q06056
names: Caution
names: Disease Annotation
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Interacts with DNAJC30; interaction is direct.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: There are three genes which encode the ATP synthase proteolipid and they specify precursors with different import sequences but identical mature proteins.
messages: This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
messages: Trimethylated by ATPSCKMT at Lys-111. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration.

9940:BMP10
gene id: 9940:BMP10
uniprot id: W5QF24
names: Similarity
messages: Belongs to the TGF-beta family.

9940:PHYHD1
gene id: 9940:PHYHD1
uniprot id: A0A6P3E9I7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPAP2
gene id: 9940:RPAP2
uniprot id: A0A6P3DZ22
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the RNA polymerase II complex. Interacts with transcribing RNA polymerase II phosphorylated on 'Ser-7' on CTD.
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Protein phosphatase that displays CTD phosphatase activity and regulates transcription of snRNA genes. Recognizes and binds phosphorylated 'Ser-7' of the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and mediates dephosphorylation of 'Ser-5' of the CTD, thereby promoting transcription of snRNA genes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLCN5
gene id: 9940:CLCN5
uniprot id: W5PK60
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:ATP1A2
gene id: 9940:ATP1A2
uniprot id: W5PEP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:MARCHF3
gene id: 9940:MARCHF3
uniprot id: A0A6P3ECP6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANTXR2
gene id: 9940:ANTXR2
uniprot id: A0A6P3EFA4
uniprot id: W5QC42
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115698
gene id: 9940:LOC101115698
uniprot id: A0A6P3TKG9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NIPAL3
gene id: 9940:NIPAL3
uniprot id: W5P9F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9940:CYP4F21
gene id: 9940:CYP4F21
uniprot id: Q9GLL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the omega-hydroxylation of prostaglandin E2. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:PSMC5
gene id: 9940:PSMC5
uniprot id: A0A6P3E889
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RARS2
gene id: 9940:RARS2
uniprot id: A0A6P3EBU0
uniprot id: W5PU06
names: Caution
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TFB2M
gene id: 9940:TFB2M
uniprot id: W5P291
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

9940:CALU
gene id: 9940:CALU
uniprot id: W5NYK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

9940:CSN1S2
gene id: 9940:CSN1S2
uniprot id: P04654
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Mammary gland specific. Secreted in milk.
messages: Secreted

9940:COG8
gene id: 9940:COG8
uniprot id: A0A836A0U2
uniprot id: W5P027
names: Caution
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SSBP1
gene id: 9940:SSBP1
uniprot id: W5PX87
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9940:LOC101123292
gene id: 9940:LOC101123292
uniprot id: W5NTP4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:LOC101116626
gene id: 9940:LOC101116626
uniprot id: W5NRZ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9940:TSFM
gene id: 9940:TSFM
uniprot id: W5P4W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

9940:GALNT8
gene id: 9940:GALNT8
uniprot id: A0A836AI33
uniprot id: W5PHV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TGFB3
gene id: 9940:TGFB3
uniprot id: W5NVG0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Transforming growth factor beta-3 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-3 (TGF-beta-3) chains, which constitute the regulatory and active subunit of TGF-beta-3, respectively.
messages: extracellular matrix

9940:SV2C
gene id: 9940:SV2C
uniprot id: W5Q5V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9940:HPCAL4
gene id: 9940:HPCAL4
uniprot id: A0A836ACV6
uniprot id: W5QFS9
names: Caution
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHKG2
gene id: 9940:PHKG2
uniprot id: B7U172
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9940:C9orf72
gene id: 9940:C9orf72
uniprot id: A0A6P3YJB7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMTC1
gene id: 9940:TMTC1
uniprot id: W5QE66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9940:ECI1
gene id: 9940:ECI1
uniprot id: A0A6P3EG65
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TLR9
gene id: 9940:TLR9
uniprot id: Q5I2M4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by proteolytic cleavage of the flexible loop between repeats LRR14 and LRR15 within the ectodomain. Cleavage requires UNC93B1. Proteolytically processed by first removing the majority of the ectodomain by either asparagine endopeptidase (AEP) or a cathepsin followed by a trimming event that is solely cathepsin mediated and required for optimal receptor signaling.
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (By similarity).
messages: Lysosome
messages: Monomer and homodimer. Exists as a monomer in the absence of unmethylated cytidine-phosphate-guanosine (CpG) ligand. Proteolytic processing of an insertion loop (Z-loop) is required for homodimerization upon binding to the unmethylated CpG ligand leading to its activation (By similarity). Interacts with MYD88 via their respective TIR domains (By similarity). Interacts with BTK (By similarity). Interacts (via transmembrane domain) with UNC93B1. Interacts with CD300LH; the interaction may promote full activation of TLR9-triggered innate responses. Interacts with CNPY3 and HSP90B1; this interaction is required for proper folding in the endoplasmic reticulum. Interacts with SMPDL3B (By similarity).
messages: phagosome

9940:DYNLL1
gene id: 9940:DYNLL1
uniprot id: A0A6P3EHY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:SERTAD3
gene id: 9940:SERTAD3
uniprot id: A0A836CX40
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RDH5
gene id: 9940:RDH5
uniprot id: W5PNM1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:IL12B
gene id: 9940:IL12B
uniprot id: P68220
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity).
messages: Belongs to the IL-12B family.
messages: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
messages: Heterodimer with IL12A; disulfide-linked. The heterodimer is known as interleukin IL-12. Heterodimer with IL23A; disulfide-linked. The heterodimer is known as interleukin IL-23. Also secreted as a monomer. Interacts with NBR1; this interaction promotes IL-12 secretion (By similarity).
messages: Secreted

9940:TMEM60
gene id: 9940:TMEM60
uniprot id: A0A6P3E8T5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRPEL1
gene id: 9940:GRPEL1
uniprot id: A0A6P3E5Q7
uniprot id: W5PPL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARV1
gene id: 9940:ARV1
uniprot id: A0A6P3EM15
uniprot id: W5NZ13
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITPA
gene id: 9940:ITPA
uniprot id: A0A6P3EIS4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Pyrophosphatase that hydrolyzes the non-canonical purine (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NRN1
gene id: 9940:NRN1
uniprot id: W5QBC3
names: Similarity
messages: Belongs to the neuritin family.

9940:MPZL1
gene id: 9940:MPZL1
uniprot id: A0A6P3E4Q0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ODF2
gene id: 9940:ODF2
uniprot id: A0A6P3YGL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9940:BIIIB4
gene id: 9940:BIIIB4
uniprot id: Q29618
names: Similarity
messages: Belongs to the KRTAP type 3 family.

9940:KIF22
gene id: 9940:KIF22
uniprot id: W5P6E6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:FNTA
gene id: 9940:FNTA
uniprot id: C5IJB1
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

9940:SHROOM4
gene id: 9940:SHROOM4
uniprot id: A0A6P3T738
uniprot id: W5PI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9940:PLBD1
gene id: 9940:PLBD1
uniprot id: A0A6P3E3S7
uniprot id: W5QHX9
names: Caution
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HGD
gene id: 9940:HGD
uniprot id: A0A6P3E6R5
uniprot id: W5QF94
names: Caution
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A35
gene id: 9940:SLC25A35
uniprot id: A0A6P3E7X9
uniprot id: W5NR92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UGCG
gene id: 9940:UGCG
uniprot id: A0A6P3E7R2
uniprot id: W5P9E0
names: Caution
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM106B
gene id: 9940:TMEM106B
uniprot id: A0A6P3TCP5
names: Similarity
messages: Belongs to the TMEM106 family.

9940:DYNLT4
gene id: 9940:DYNLT4
uniprot id: A0A836APG5
uniprot id: W5PJC5
names: Caution
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GAPDH
gene id: 9940:GAPDH
uniprot id: A0A6P9FRF8
uniprot id: D7R7V6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PFDN2
gene id: 9940:PFDN2
uniprot id: A0A6P3E4N1
uniprot id: W5PID4
names: Caution
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM114A2
gene id: 9940:FAM114A2
uniprot id: A0A6P3E4Y4
uniprot id: A0A6P3TP31
names: Caution
names: Similarity
messages: Belongs to the FAM114 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB11FIP2
gene id: 9940:RAB11FIP2
uniprot id: A0A6P3EFV6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MANBAL
gene id: 9940:MANBAL
uniprot id: W5Q8Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0239 family.
messages: Membrane

9940:MPP1
gene id: 9940:MPP1
uniprot id: A0A6P3ES90
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: stereocilium

9940:TMEM79
gene id: 9940:TMEM79
uniprot id: A0A836D9Z0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DCAF1
gene id: 9940:DCAF1
uniprot id: A0A6P3TE50
uniprot id: W5PCE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKAG1
gene id: 9940:PRKAG1
uniprot id: A0A6P3YIN1
names: Caution
names: Similarity
names: Subunit
messages: AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.
messages: Belongs to the 5'-AMP-activated protein kinase gamma subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GK
gene id: 9940:GK
uniprot id: W5Q9M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

9940:LOC101113787
gene id: 9940:LOC101113787
uniprot id: W5Q615
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SERINC1
gene id: 9940:SERINC1
uniprot id: A0A6P3EGP8
uniprot id: W5PEF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ABI1
gene id: 9940:ABI1
uniprot id: A0A6P3EK40
uniprot id: W5Q3F7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

9940:HSP90B1
gene id: 9940:HSP90B1
uniprot id: A0A6P3TF14
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NIPA2
gene id: 9940:NIPA2
uniprot id: A0A6P3E638
uniprot id: A0A6P3TCA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDCD11
gene id: 9940:PDCD11
uniprot id: W5P0M8
names: Subcellular Location Annotation
messages: nucleolus

9940:LOC101123492
gene id: 9940:LOC101123492
uniprot id: W5PAY1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SSR3
gene id: 9940:SSR3
uniprot id: A0A6P3E727
uniprot id: W5NYA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111300
gene id: 9940:LOC101111300
uniprot id: A0A836A176
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MKRN2
gene id: 9940:MKRN2
uniprot id: W5Q2I1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:EFNA5
gene id: 9940:EFNA5
uniprot id: A0A6P3EDA9
uniprot id: W5QBQ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FKBP7
gene id: 9940:FKBP7
uniprot id: A0A836AJS2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GADD45A
gene id: 9940:GADD45A
uniprot id: A0A6P3E572
uniprot id: W5PNZ3
names: Caution
names: Similarity
messages: Belongs to the GADD45 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLSCR4
gene id: 9940:PLSCR4
uniprot id: A0A6P3E576
uniprot id: A0A6P3YJC9
names: Caution
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM126B
gene id: 9940:TMEM126B
uniprot id: W5P4W9
names: Subcellular Location Annotation
messages: Membrane

9940:CD27
gene id: 9940:CD27
uniprot id: A0A6P3E3Y0
uniprot id: W5PER9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INHBC
gene id: 9940:INHBC
uniprot id: A0A836A899
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMAD7
gene id: 9940:SMAD7
uniprot id: W5P0W2
names: Subcellular Location Annotation
messages: Nucleus

9940:GBF1
gene id: 9940:GBF1
uniprot id: W5Q8R3
names: Subcellular Location Annotation
messages: Golgi apparatus

9940:STON2
gene id: 9940:STON2
uniprot id: W5NYA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm

9940:HOXB7
gene id: 9940:HOXB7
uniprot id: W5PAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9940:PACSIN2
gene id: 9940:PACSIN2
uniprot id: A0A6P3TKP6
uniprot id: A0A6P3YKT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

9940:NDUFB1
gene id: 9940:NDUFB1
uniprot id: A0A6P3EEC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNK3
gene id: 9940:KCNK3
uniprot id: A0A6P3CXB1
uniprot id: E5L8E3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLC4
gene id: 9940:KLC4
uniprot id: A0A6P3ENN0
uniprot id: A0A6P7D7T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:C7H15orf65
gene id: 9940:C7H15orf65
uniprot id: A0A6P3TFT4
uniprot id: W5QIB1
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium axoneme

9940:FARSB
gene id: 9940:FARSB
uniprot id: A0A836AGU2
uniprot id: W5QGI4
names: Caution
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HEPACAM
gene id: 9940:HEPACAM
uniprot id: A0A6P3T8G1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIP5K1A
gene id: 9940:PIP5K1A
uniprot id: A0A6P3E740
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNRNPA3
gene id: 9940:HNRNPA3
uniprot id: A0A6P3E192
names: Subcellular Location Annotation
messages: Nucleus

9940:RPL30
gene id: 9940:RPL30
uniprot id: A0A836A0U0
uniprot id: W5PMC5
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC2A12
gene id: 9940:SLC2A12
uniprot id: W5PZ66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

9940:UBLCP1
gene id: 9940:UBLCP1
uniprot id: W5PU58
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

9940:CD3G
gene id: 9940:CD3G
uniprot id: A0A6P3EG79
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEP20
gene id: 9940:CEP20
uniprot id: A0A6P3EE51
uniprot id: W5PHQ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centriole
messages: cilium basal body

9940:SERBP1
gene id: 9940:SERBP1
uniprot id: A0A6P3DYD4
uniprot id: W5PNR4
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FMNL3
gene id: 9940:FMNL3
uniprot id: A0A6P3TLF8
uniprot id: W5QAL6
names: Caution
names: Similarity
messages: Belongs to the formin homology family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZZZ3
gene id: 9940:ZZZ3
uniprot id: A0A836D6K4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB33A
gene id: 9940:RAB33A
uniprot id: A0A6P3EFA9
uniprot id: W5Q1J6
names: Caution
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAGR1
gene id: 9940:PAGR1
uniprot id: A0A6P3T9V5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107908
gene id: 9940:LOC101107908
uniprot id: W5PWM7
uniprot id: W5PWM8
names: Similarity
messages: Belongs to the MHC class I family.

9940:CAV2
gene id: 9940:CAV2
uniprot id: Q09YJ1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Acts as an accessory protein in conjunction with CAV1 in targeting to lipid rafts and driving caveolae formation. Positive regulator of cellular mitogenesis of the MAPK signaling pathway. Required for the insulin-stimulated nuclear translocation and activation of MAPK1 and STAT3, and the subsequent regulation of cell cycle progression (By similarity).
messages: Monomer or homodimer (By similarity). Interacts with CAV1; the interaction forms a stable heterooligomeric complex that is required for targeting to lipid rafts and for caveolae formation. Tyrosine phosphorylated forms do not form heterooligomers with the Tyr-19-phosphorylated form existing as a monomer or dimer, and the Tyr-27-form as a monomer only. Interacts (tyrosine phosphorylated form) with the SH2 domain-containing proteins, RASA1, NCK1 and SRC. Interacts (tyrosine phosphorylated form) with INSR, the interaction (Tyr-27-phosphorylated form) is increased on insulin stimulation. Interacts (Tyr-19 phosphorylated form) with MAPK1 (phosphorylated form); the interaction, promoted by insulin, leads to nuclear location and MAPK1 activation. Interacts with STAT3; the interaction is increased on insulin-induced tyrosine phosphorylation leading to STAT activation (By similarity).
messages: Nucleus
messages: Phosphorylated on serine and tyrosine residues. CAV1 promotes phosphorylation on Ser-23 which then targets the complex to the plasma membrane, lipid rafts and caveolae. Phosphorylation on both Tyr-19 and Tyr-27 is required for insulin-induced 'Ser-727' phosphorylation of STAT3 and its activation. Phosphorylation on Tyr-19 is required for insulin-induced phosphorylation of MAPK1 and DNA binding of STAT3. Tyrosine phosphorylation is induced by both EGF and insulin (By similarity).
messages: caveola

9940:RASGRP3
gene id: 9940:RASGRP3
uniprot id: A0A6P3TJ60
names: Similarity
messages: Belongs to the RASGRP family.

9940:ST3GAL1
gene id: 9940:ST3GAL1
uniprot id: A0A6P3TRV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRIM1
gene id: 9940:PRIM1
uniprot id: W5PEB9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9940:MED4
gene id: 9940:MED4
uniprot id: A0A6P7E063
uniprot id: A0A836D264
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MSGN1
gene id: 9940:MSGN1
uniprot id: A0A6P3E2G2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GYS2
gene id: 9940:GYS2
uniprot id: A0A6P3E3P8
names: Caution
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

9940:BSP1
gene id: 9940:BSP1
uniprot id: B7VBV2
names: Caution
names: Similarity
messages: Belongs to the seminal plasma protein family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:CFTR
gene id: 9940:CFTR
uniprot id: Q00555
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Binds and hydrolyzes ATP via the two cytoplasmic ABC transporter nucleotide-binding domains. The two ATP-binding domains interact with each other, forming a head-to-tail dimer. Normal ATPase activity requires interaction between the two domains. The first ABC transporter nucleotide-binding domain has no ATPase activity by itself.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane (By similarity). Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3)(-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. Modulates the activity of the epithelial sodium channel (ENaC) complex, in part by regulating the cell surface expression of the ENaC complex. May regulate bicarbonate secretion and salvage in epithelial cells by regulating the transporter SLC4A7. Can inhibit the chloride channel activity of ANO1 (By similarity). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and SLC9A3R1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through SLC9A3R1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation (By similarity).
messages: N-glycosylated.
messages: Nucleus
messages: Phosphorylated; cAMP treatment promotes phosphorylation and activates the channel. Dephosphorylation decreases the ATPase activity (in vitro). Phosphorylation at PKA sites activates the channel. Phosphorylation at PKC sites enhances the response to phosphorylation by PKA. Phosphorylated by AMPK; this inhibits channel activity.
messages: Recycling endosome membrane
messages: The PDZ-binding motif mediates interactions with GOPC and with the SLC4A7, SLC9A3R1/EBP50 complex.
messages: The disordered R region mediates channel activation when it is phosphorylated, but not in the absence of phosphorylation.
messages: Ubiquitinated, leading to its degradation in the lysosome. Deubiquitination by USP10 in early endosomes enhances its endocytic recycling to the cell membrane. Ubiquitinated by RNF185 during ER stress. Ubiquitinated by MARCHF2 (By similarity).

9940:TKDP1
gene id: 9940:TKDP1
uniprot id: Q29428
names: Developmental Stage
names: Function
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Expressed only in the trophectoderm, which forms the outer epithelial layer of the trophoblast.
messages: Maximal expression at days 14 and 16 of pregnancy.
messages: May play a role in mediating maternal-conceptus interactions in the immediate preimplantation period. Does not seem to have proteinase inhibitory activity.
messages: Secreted

9940:AK7
gene id: 9940:AK7
uniprot id: A0A6P3EC03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CMTR1
gene id: 9940:CMTR1
uniprot id: A0A6P3YRY7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with POLR2A (via C-terminus).
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates RNA cap1 2'-O-ribose methylation to the 5'-cap structure of RNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA to produce m(7)GpppNmp (cap1).
messages: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL3
gene id: 9940:ARL3
uniprot id: A0A6P9FQM1
uniprot id: C5IWU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome

9940:BCL2L14
gene id: 9940:BCL2L14
uniprot id: A0A6P3EB87
uniprot id: W5QI98
names: Caution
names: Similarity
messages: Belongs to the Bcl-2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MANSC1
gene id: 9940:MANSC1
uniprot id: A0A6P3E884
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GC
gene id: 9940:GC
uniprot id: A0A836A4N3
uniprot id: W5PTG9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NGLY1
gene id: 9940:NGLY1
uniprot id: W5P200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglutaminase-like superfamily. PNGase family.
messages: Cytoplasm

9940:TXNL4B
gene id: 9940:TXNL4B
uniprot id: A0A6P3EC91
uniprot id: A0A6P3EJK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104224
gene id: 9940:LOC101104224
uniprot id: W5QDC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

9940:TADA1
gene id: 9940:TADA1
uniprot id: A0A6P3E4P6
uniprot id: W5PQI8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TADA1 family.
messages: Component of the STAGA transcription coactivator-HAT complex, at least composed of SUPT3H, GCN5L2, TAF5L, TAF6L, SUPT7L, TADA3L, TAD1L, TAF10, TAF12, TRRAP and TAF9.
messages: Nucleus
messages: Probably involved in transcriptional regulation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BCLAF3
gene id: 9940:BCLAF3
uniprot id: A0A6P3YU93
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9940:NDUFA7
gene id: 9940:NDUFA7
uniprot id: A0A6P3E9B7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBX1
gene id: 9940:RBX1
uniprot id: A0A6P3E417
names: Caution
names: Similarity
messages: Belongs to the RING-box family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A12
gene id: 9940:SLC39A12
uniprot id: W5PT04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

9940:TNRC6B
gene id: 9940:TNRC6B
uniprot id: W5Q712
names: Similarity
messages: Belongs to the GW182 family.

9940:LOC101115061
gene id: 9940:LOC101115061
uniprot id: W5Q7B2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:BACE1
gene id: 9940:BACE1
uniprot id: A0A6P3EG74
uniprot id: W5P5U5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: trans-Golgi network

9940:YKT6
gene id: 9940:YKT6
uniprot id: A0A6P3EC11
uniprot id: W5Q2V0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

9940:GIT2
gene id: 9940:GIT2
uniprot id: A0A6P3ENR1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FEN1
gene id: 9940:FEN1
uniprot id: C8BKD0
uniprot id: W5Q231
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated by EP300. Acetylation inhibits both endonuclease and exonuclease activity. Acetylation also reduces DNA-binding activity but does not affect interaction with PCNA or EP300.
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity. The C-terminal domain binds EP300. Can bind simultaneously to both PCNA and EP300. Interacts with DDX11.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylation at Arg-184 by PRMT5 impedes Ser-179 phosphorylation and increases interaction with PCNA.
messages: Methylation at Arg-192 by PRMT5 impedes Ser-187 phosphorylation and increases interaction with PCNA.
messages: Mitochondrion
messages: Phosphorylation upon DNA damage induces relocalization to the nuclear plasma. Phosphorylation at Ser-179 by CDK2 occurs during late S-phase and results in dissociation from PCNA.
messages: Phosphorylation upon DNA damage induces relocalization to the nuclear plasma. Phosphorylation at Ser-187 by CDK2 occurs during late S-phase and results in dissociation from PCNA.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity. The C-terminal domain binds EP300; can bind simultaneously to both PCNA and EP300. Interacts with PCNA; can bind simultaneously to both PCNA and EP300. Interacts with DDX11; this interaction is direct and increases flap endonuclease activity of FEN1. Interacts with WDR4; regulating its endonuclease activity.
messages: nucleolus
messages: nucleoplasm

9940:UBA6
gene id: 9940:UBA6
uniprot id: W5PBH2
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9940:ZCCHC10
gene id: 9940:ZCCHC10
uniprot id: A0A6P3EE03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:APOM
gene id: 9940:APOM
uniprot id: A0A6P3ENU5
uniprot id: A0A6P7D7D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
messages: Interacts with LRP2; LRP2 mediates APOM renal uptake and subsequent lysosomal degradation.
messages: Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AP1G1
gene id: 9940:AP1G1
uniprot id: W5P0Z7
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9940:MFSD11
gene id: 9940:MFSD11
uniprot id: A0A6P3TS43
uniprot id: A0A836CXK3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANAPC4
gene id: 9940:ANAPC4
uniprot id: A0A6P3E6T3
names: Caution
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TIA1
gene id: 9940:TIA1
uniprot id: A0A6P3E2I7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102714
gene id: 9940:LOC101102714
uniprot id: M9PPI3
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9940:IGFBP5
gene id: 9940:IGFBP5
uniprot id: A0A6P9FQC5
uniprot id: B3GS77
names: Caution
names: Function
names: Subcellular Location Annotation
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108419
gene id: 9940:LOC101108419
uniprot id: W5PNP2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9940:KRT82
gene id: 9940:KRT82
uniprot id: W5Q6H2
names: Similarity
messages: Belongs to the intermediate filament family.

9940:ILK
gene id: 9940:ILK
uniprot id: A0A6P3T4M6
uniprot id: A0A6P3TF04
uniprot id: H9CH14
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

9940:IPO7
gene id: 9940:IPO7
uniprot id: A0A835ZZ83
uniprot id: W5PT14
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC190
gene id: 9940:CCDC190
uniprot id: A0A6P3E7I3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLEKHA8
gene id: 9940:PLEKHA8
uniprot id: W5PF15
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

9940:YARS2
gene id: 9940:YARS2
uniprot id: W5QDG4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9940:TOMM5
gene id: 9940:TOMM5
uniprot id: W5PP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

9940:DCK
gene id: 9940:DCK
uniprot id: W5PR96
names: Similarity
messages: Belongs to the DCK/DGK family.

9940:ALG6
gene id: 9940:ALG6
uniprot id: W5PIT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:GLYCTK
gene id: 9940:GLYCTK
uniprot id: W5P6K4
names: Similarity
messages: Belongs to the glycerate kinase type-2 family.

9940:CAB39L
gene id: 9940:CAB39L
uniprot id: A0A6P3E7D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

9940:DUS1L
gene id: 9940:DUS1L
uniprot id: A0A6P3TID6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRELD1
gene id: 9940:CRELD1
uniprot id: A0A6P3T753
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LOC101122122
gene id: 9940:LOC101122122
uniprot id: A0A6P3EE32
uniprot id: W5PHD1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTCD3
gene id: 9940:PTCD3
uniprot id: W5QHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS39 family.
messages: Mitochondrion

9940:PLA2G2C
gene id: 9940:PLA2G2C
uniprot id: W5PHZ6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9940:LOC101111607
gene id: 9940:LOC101111607
uniprot id: A0A6P3E209
uniprot id: A0A6P3TI08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZBTB8OS
gene id: 9940:ZBTB8OS
uniprot id: A0A6P3E6M7
uniprot id: W5QID8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPSF2
gene id: 9940:CPSF2
uniprot id: A0A835ZPH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHACTR3
gene id: 9940:PHACTR3
uniprot id: W5Q2S3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9940:LOC101116896
gene id: 9940:LOC101116896
uniprot id: W5QIL5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:LOC101107098
gene id: 9940:LOC101107098
uniprot id: A0A6P3EA32
uniprot id: W5NTE7
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPS9
gene id: 9940:MRPS9
uniprot id: A0A6P3E2T7
uniprot id: W5PU00
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRR1
gene id: 9940:KRR1
uniprot id: W5PZK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

9940:AGTR2
gene id: 9940:AGTR2
uniprot id: A0A6P3TBB4
uniprot id: Q28929
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Helix VIII may act as a gatekeeper for either suppression or activation of the receptor, depending on post-translational modifications and interactions with various receptor partners. Helix VIII is found in a non-canonical position, stabilizing the active-like state, but at the same time preventing the recruitment of G-proteins or beta-arrestins. Upon switching to a membrane-bound conformation, helix VIII can support the recruitment of G proteins and beta-arrestins.
messages: Interacts with MTUS1.
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide. Signals primarily via a non-canonical G-protein- and beta-arrestin independent pathways. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNJ8
gene id: 9940:KCNJ8
uniprot id: A0A6P3EC81
uniprot id: W5QGC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDCA8
gene id: 9940:CDCA8
uniprot id: A0A836ANX9
uniprot id: W5QEZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the borealin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centromere

9940:PKD1L2
gene id: 9940:PKD1L2
uniprot id: W5PEX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:SREK1IP1
gene id: 9940:SREK1IP1
uniprot id: A0A6P3EB35
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RASGRP2
gene id: 9940:RASGRP2
uniprot id: A0A6P3EQM4
names: Similarity
messages: Belongs to the RASGRP family.

9940:LOC101106166
gene id: 9940:LOC101106166
uniprot id: W5Q5K4
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

9940:TSPO
gene id: 9940:TSPO
uniprot id: Q9GMC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TspO/BZRP family.
messages: Interacts with TSPOAP1 (By similarity). Interacts with MOST-1 (By similarity). May interact with STAR.
messages: Mitochondrion membrane
messages: Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. It is apparently not required for steroid hormone biosynthesis. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme (By similarity). Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides (PubMed:11145616).

9940:MTHFD1
gene id: 9940:MTHFD1
uniprot id: W5QJ32
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

9940:APOD
gene id: 9940:APOD
uniprot id: W5QGP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9940:LOC101116991
gene id: 9940:LOC101116991
uniprot id: W5PUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:KEF53 p10
gene id: 9940:KEF53_p10
uniprot id: A0A0E3LZY8
uniprot id: O78750
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Binds a dinuclear copper A center per subunit.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome (By similarity). The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (PubMed:27654913). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16 (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9940:LYPLA2
gene id: 9940:LYPLA2
uniprot id: W5PB50
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9940:TIMM17A
gene id: 9940:TIMM17A
uniprot id: A0A6P3YKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM71
gene id: 9940:TMEM71
uniprot id: A0A836AC59
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1QTNF6
gene id: 9940:C1QTNF6
uniprot id: A0A6P3EC46
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SDR16C5
gene id: 9940:SDR16C5
uniprot id: C5IS98
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:LOC101108911
gene id: 9940:LOC101108911
uniprot id: W5Q4A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SDHC
gene id: 9940:SDHC
uniprot id: A0A6P3E4N8
uniprot id: W5PJW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b560 family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF711
gene id: 9940:ZNF711
uniprot id: A0A6P7DIQ0
names: Subcellular Location Annotation
messages: Nucleus

9940:CRHR1
gene id: 9940:CRHR1
uniprot id: O62772
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: C-terminal Ser or Thr residues may be phosphorylated.
messages: Cell membrane
messages: Endosome
messages: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal embryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
messages: Heterodimer; heterodimerizes with GPER1. Interacts (via N-terminal extracellular domain) with CRH and UCN. Interacts with DLG1; this inhibits endocytosis of CRHR1 after agonist binding (By similarity).
messages: Phosphorylation at Ser-301 by PKA prevents maximal coupling to Gq-protein, and thereby negatively regulates downstream signaling.
messages: The transmembrane domain is composed of seven transmembrane helices that are arranged in V-shape. Transmembrane helix 7 assumes a sharply kinked structure (By similarity).

9940:TAPBPL
gene id: 9940:TAPBPL
uniprot id: A0A6P3ECG5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD79B
gene id: 9940:CD79B
uniprot id: W5PX57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:CCDC167
gene id: 9940:CCDC167
uniprot id: A0A6P3EJ13
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GAR1
gene id: 9940:GAR1
uniprot id: A0A6P3E577
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

9940:SF3B3
gene id: 9940:SF3B3
uniprot id: A0A6P3EJ99
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL7
gene id: 9940:IL7
uniprot id: Q28540
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis. Mechanistically, exerts its biological effects through a receptor composed of IL7RA subunit and the cytokine receptor common subunit gamma/CSF2RG. Binding to the receptor leads to activation of various kinases including JAK1 or JAK3 depending on the cell type and subsequently propagation of signals through activation of several downstream signaling pathways including the PI3K/Akt/mTOR or the JAK-STAT5.
messages: Interacts with IL7R and CSF2RG.
messages: Secreted

9940:GPANK1
gene id: 9940:GPANK1
uniprot id: A0A6P3YP94
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LSM2
gene id: 9940:LSM2
uniprot id: A0A6P3EPY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEC24B
gene id: 9940:SEC24B
uniprot id: W5P912
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9940:ATG101
gene id: 9940:ATG101
uniprot id: A0A6P3E320
names: Caution
names: Similarity
messages: Belongs to the ATG101 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115778
gene id: 9940:LOC101115778
uniprot id: W5QII5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9940:PSMA8
gene id: 9940:PSMA8
uniprot id: W5PB07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9940:PRLHR
gene id: 9940:PRLHR
uniprot id: A0A6P3CWY0
uniprot id: B2KTD0
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFAIP3
gene id: 9940:TNFAIP3
uniprot id: W5NQZ0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:NUDT7
gene id: 9940:NUDT7
uniprot id: W5PCU2
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

9940:TNFAIP1
gene id: 9940:TNFAIP1
uniprot id: A0A6P3E9R4
names: Caution
names: Similarity
messages: Belongs to the BACURD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUP43
gene id: 9940:NUP43
uniprot id: A0A6P3E6Z9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLA2G1B
gene id: 9940:PLA2G1B
uniprot id: W5PR24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9940:IFI30
gene id: 9940:IFI30
uniprot id: F1ASZ5
names: Similarity
names: Subunit
messages: Belongs to the GILT family.
messages: Dimer; disulfide-linked.

9940:ENTPD6
gene id: 9940:ENTPD6
uniprot id: W5PAG5
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9940:LAMP3
gene id: 9940:LAMP3
uniprot id: W5QHK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9940:PRDM10
gene id: 9940:PRDM10
uniprot id: W5PYN6
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9940:GSTCD
gene id: 9940:GSTCD
uniprot id: A0A6P7E8U1
uniprot id: A0A836AEX7
names: Caution
names: Similarity
messages: Belongs to the GSTCD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPM1K
gene id: 9940:PPM1K
uniprot id: W5NU64
names: Similarity
messages: Belongs to the PP2C family.

9940:TPP1
gene id: 9940:TPP1
uniprot id: W5Q686
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9940:GNPDA1
gene id: 9940:GNPDA1
uniprot id: W5NUG3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9940:B3GNT9
gene id: 9940:B3GNT9
uniprot id: A0A6P3EC79
uniprot id: A0A6P3TZ08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PFKFB3
gene id: 9940:PFKFB3
uniprot id: A0A6P3YKN7
names: Caution
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SCGN
gene id: 9940:SCGN
uniprot id: A0A6P3ECX7
uniprot id: W5NZ64
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: secretory vesicle membrane

9940:KIF2A
gene id: 9940:KIF2A
uniprot id: A0A6P3YRD9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:SENP3
gene id: 9940:SENP3
uniprot id: W5PY22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9940:MORN3
gene id: 9940:MORN3
uniprot id: A0A6P3EHU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104697
gene id: 9940:LOC101104697
uniprot id: W5Q1S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SARS1
gene id: 9940:SARS1
uniprot id: W5QCS4
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.

9940:PBLD
gene id: 9940:PBLD
uniprot id: A0A6P3EGP1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OGDH
gene id: 9940:OGDH
uniprot id: W5PZR4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9940:TAPT1
gene id: 9940:TAPT1
uniprot id: W5PKF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

9940:LOC101107056
gene id: 9940:LOC101107056
uniprot id: W5P5D3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:LOC106991069
gene id: 9940:LOC106991069
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAH3
gene id: 9940:DNAH3
uniprot id: W5PWS5
names: Similarity
messages: Belongs to the dynein heavy chain family.

9940:NUP98
gene id: 9940:NUP98
uniprot id: W5NVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

9940:LAPTM4A
gene id: 9940:LAPTM4A
uniprot id: W5Q6M3
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9940:LOC101119685
gene id: 9940:LOC101119685
uniprot id: A0A6P3EQP7
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CD45/PTPRC.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BAMBI
gene id: 9940:BAMBI
uniprot id: A0A835ZXZ3
uniprot id: Q8HYZ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BAMBI family.
messages: Membrane
messages: Negatively regulates TGF-beta signaling.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS6
gene id: 9940:RPS6
uniprot id: A0A6P3E9D6
uniprot id: W5PXV8
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZCRB1
gene id: 9940:ZCRB1
uniprot id: A0A6P3EDX0
uniprot id: A0A6P3TPY4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AP3M2
gene id: 9940:AP3M2
uniprot id: W5NYM8
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9940:LOC101111215
gene id: 9940:LOC101111215
uniprot id: A0A6P3EKA6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUS1
gene id: 9940:NUS1
uniprot id: A0A6P3EBM8
names: Caution
names: Similarity
messages: Belongs to the UPP synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF143
gene id: 9940:ZNF143
uniprot id: A0A6P3EM42
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C9
gene id: 9940:C9
uniprot id: W5PID9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted
messages: Target cell membrane

9940:LOC101119356
gene id: 9940:LOC101119356
uniprot id: A0A836AN27
uniprot id: W5NWA3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOXB5
gene id: 9940:HOXB5
uniprot id: W5PAS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9940:PSMD9
gene id: 9940:PSMD9
uniprot id: A0A6P3EM77
uniprot id: W5PSC3
names: Caution
names: Similarity
messages: Belongs to the proteasome subunit p27 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AQP7
gene id: 9940:AQP7
uniprot id: A0A6P3E0N6
uniprot id: A0A6P3TGM9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PANX3
gene id: 9940:PANX3
uniprot id: A0A6P3ED75
uniprot id: W5PL29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: gap junction

9940:ARAF
gene id: 9940:ARAF
uniprot id: A0A6P3CXM2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9940:DBI
gene id: 9940:DBI
uniprot id: A0A6P3E1H6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TGIF2
gene id: 9940:TGIF2
uniprot id: W5Q2W8
names: Subcellular Location Annotation
messages: Nucleus

9940:RELL2
gene id: 9940:RELL2
uniprot id: A0A6P3E4U4
uniprot id: A0A6P7E4W6
names: Caution
names: Similarity
messages: Belongs to the RELT family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC106990092
gene id: 9940:LOC106990092
uniprot id: A0A835ZM35
uniprot id: P62896
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme c group covalently per subunit.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Phosphorylation at Tyr-49 and Tyr-98 both reduce by half the turnover in the reaction with cytochrome c oxidase, down-regulating mitochondrial respiration.
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C18H14orf28
gene id: 9940:C18H14orf28
uniprot id: A0A6P7D4N1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YES1
gene id: 9940:YES1
uniprot id: W5PIG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9940:LOC101111566
gene id: 9940:LOC101111566
uniprot id: W5Q8H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9940:DCTN4
gene id: 9940:DCTN4
uniprot id: A0A6P3ED33
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IARS1
gene id: 9940:IARS1
uniprot id: A0A6P3T845
names: Caution
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109826
gene id: 9940:LOC101109826
uniprot id: W5P8U0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CASP3
gene id: 9940:CASP3
uniprot id: A0A6P3YQC8
names: Similarity
messages: Belongs to the peptidase C14A family.

9940:CORO6
gene id: 9940:CORO6
uniprot id: A0A836A964
names: Caution
names: Similarity
messages: Belongs to the WD repeat coronin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104041
gene id: 9940:LOC101104041
uniprot id: W5QEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

9940:ATP2A1
gene id: 9940:ATP2A1
uniprot id: A0A6P3ERL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FERMT2
gene id: 9940:FERMT2
uniprot id: A0A836D1N1
names: Caution
names: Similarity
messages: Belongs to the kindlin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLIPR1
gene id: 9940:GLIPR1
uniprot id: A0A6P3E7H0
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CWC25
gene id: 9940:CWC25
uniprot id: A0A6P3EHD3
uniprot id: W5PJN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWC25 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNN3
gene id: 9940:KCNN3
uniprot id: W5NYB3
names: Subcellular Location Annotation
messages: Membrane

9940:LCA5L
gene id: 9940:LCA5L
uniprot id: W5PJ29
names: Similarity
messages: Belongs to the LCA5 family.

9940:LOC100101238
gene id: 9940:LOC100101238
uniprot id: A6N7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9940:CDK12
gene id: 9940:CDK12
uniprot id: A0A6P3E844
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RARG
gene id: 9940:RARG
uniprot id: T1UNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9940:CACNB3
gene id: 9940:CACNB3
uniprot id: W5QCW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Cytoplasm

9940:S100A16
gene id: 9940:S100A16
uniprot id: A0A6P3E767
uniprot id: A0A6P3TJ17
names: Caution
names: Similarity
messages: Belongs to the S-100 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THEM5
gene id: 9940:THEM5
uniprot id: A0A6P3E750
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD70
gene id: 9940:CD70
uniprot id: W5P639
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9940:CDC5L
gene id: 9940:CDC5L
uniprot id: W5PKH2
names: Similarity
messages: Belongs to the CEF1 family.

9940:NDUFA12
gene id: 9940:NDUFA12
uniprot id: A0A8N7XJ18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCR8
gene id: 9940:CCR8
uniprot id: W5PX65
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:APEH
gene id: 9940:APEH
uniprot id: A0A6P3EPI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S9C family.
messages: Cytoplasm
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This enzyme catalyzes the hydrolysis of the N-terminal peptide bond of an N-acetylated peptide to generate an N-acetylated amino acid and a peptide with a free N-terminus. It preferentially cleaves off Ac-Ala, Ac-Met and Ac-Ser.

9940:TXN
gene id: 9940:TXN
uniprot id: P50413
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioredoxin family.
messages: Cytoplasm
messages: Homodimer; disulfide-linked. Interacts with TXNIP through the redox-active site. Interacts with MAP3K5 and CASP3. Interacts with APEX1; the interaction stimulates the FOS/JUN AP-1 DNA-binding activity in a redox-dependent manner (By similarity).
messages: In the fully reduced protein, both Cys-69 and Cys-73 are nitrosylated in response to nitric oxide (NO). When two disulfide bonds are present in the protein, only Cys-73 is nitrosylated. Cys-73 can serve as donor for nitrosylation of target proteins (By similarity).
messages: Nucleus
messages: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity (By similarity).
messages: Secreted

9940:LOC101103771
gene id: 9940:LOC101103771
uniprot id: W5NQJ0
names: Similarity
messages: Belongs to the S-100 family.

9940:TMEM242
gene id: 9940:TMEM242
uniprot id: A0A6P3EC18
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF2B1
gene id: 9940:EIF2B1
uniprot id: W5NYY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.
messages: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.
messages: Complex of five different subunits; alpha, beta, gamma, delta and epsilon.

9940:STAC
gene id: 9940:STAC
uniprot id: W5Q4J8
names: Subcellular Location Annotation
messages: sarcolemma

9940:IGFBP6
gene id: 9940:IGFBP6
uniprot id: B5AN56
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:VWA5A
gene id: 9940:VWA5A
uniprot id: A0A6P3EPU2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ILF2
gene id: 9940:ILF2
uniprot id: A0A6P3DZP2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP77
gene id: 9940:CFAP77
uniprot id: A0A6P3E459
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VTI1B
gene id: 9940:VTI1B
uniprot id: A0A836AEX3
uniprot id: W5QJ55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNASE1L1
gene id: 9940:DNASE1L1
uniprot id: W5P4H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9940:LOC101113937
gene id: 9940:LOC101113937
uniprot id: W5PRF6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CYP2C19
gene id: 9940:CYP2C19
uniprot id: F1CGV0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:FBXO38
gene id: 9940:FBXO38
uniprot id: A0A6P3TSL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SF3B6
gene id: 9940:SF3B6
uniprot id: A0A6P3E250
uniprot id: W5Q8S3
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120067
gene id: 9940:LOC101120067
uniprot id: A0A6P3EAV4
uniprot id: W5QAG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB1
gene id: 9940:PSMB1
uniprot id: A0A6P3E722
uniprot id: W5P500
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TCTE1
gene id: 9940:TCTE1
uniprot id: A0A6P7D6N0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZDHHC13
gene id: 9940:ZDHHC13
uniprot id: W5PGN8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9940:EIF2B2
gene id: 9940:EIF2B2
uniprot id: W5NTZ6
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

9940:CAST
gene id: 9940:CAST
uniprot id: Q95208
names: Domain
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Each of the four flexible inhibitory domains can inhibit one calcium-bound calpain molecule by occupying both sides of the active site.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue (By similarity).

9940:FICD
gene id: 9940:FICD
uniprot id: A0A6P3TGJ1
names: Caution
names: Similarity
messages: Belongs to the fic family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM174
gene id: 9940:TMEM174
uniprot id: A0A6P3EN34
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115927
gene id: 9940:LOC101115927
uniprot id: A0A6P3E736
uniprot id: W5P0X1
names: Caution
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTLL1
gene id: 9940:TTLL1
uniprot id: A0A6P7DZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin polyglutamylase family.
messages: cilium basal body

9940:TNF
gene id: 9940:TNF
uniprot id: A5YBV0
uniprot id: P23383
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6 (By similarity).
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance (By similarity). Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces GKAP42 protein degradation in adipocytes which is partially responsible for TNF-induced insulin resistance. Plays a role in angiogenesis by inducing VEGF production synergistically with IL1B and IL6.
messages: Homotrimer. Interacts with SPPL2B (By similarity).
messages: Homotrimer. Interacts with SPPL2B.
messages: Membrane
messages: O-glycosylated; glycans contain galactose, N-acetylgalactosamine and N-acetylneuraminic acid.
messages: Secreted
messages: The TNF intracellular domain (ICD) form induces IL12 production in dendritic cells.
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1 (By similarity).
messages: The membrane form, but not the soluble form, is phosphorylated on serine residues. Dephosphorylation of the membrane form occurs by binding to soluble TNFRSF1A/TNFR1.
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space (By similarity).
messages: The soluble form derives from the membrane form by proteolytic processing. The membrane-bound form is further proteolytically processed by SPPL2A or SPPL2B through regulated intramembrane proteolysis producing TNF intracellular domains (ICD1 and ICD2) released in the cytosol and TNF C-domain 1 and C-domain 2 secreted into the extracellular space.
messages: The soluble form is demyristoylated by SIRT6, promoting its secretion.

9940:INPP4B
gene id: 9940:INPP4B
uniprot id: W5PQC2
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

9940:TTC4
gene id: 9940:TTC4
uniprot id: W5PC03
names: Similarity
messages: Belongs to the TTC4 family.

9940:DRC1
gene id: 9940:DRC1
uniprot id: W5QBW2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DRC1 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC).
messages: cilium axoneme
messages: flagellum axoneme

9940:LOC101110922
gene id: 9940:LOC101110922
uniprot id: W5PPP0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:STXBP3
gene id: 9940:STXBP3
uniprot id: W5QCA2
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9940:RSPH9
gene id: 9940:RSPH9
uniprot id: A0A6P3ENN6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MITF
gene id: 9940:MITF
uniprot id: W5PJC4
uniprot id: W5PJC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

9940:SCD5
gene id: 9940:SCD5
uniprot id: A9QVT2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9940:SFN
gene id: 9940:SFN
uniprot id: O77642
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 14-3-3 proteins have been shown to be PKC activators, but this effect could be non-specific and only due to the acidic nature of the protein.
messages: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53 (By similarity).
messages: Belongs to the 14-3-3 family.
messages: Cytoplasm
messages: Homodimer. Found in a complex with XPO7, EIF4A1, ARHGAP1, VPS26A, VPS29 and VPS35. Interacts with KRT17. Interacts with GAB2 and SAMSN1 (By similarity). Interacts with SRPK2 (By similarity). Interacts with COPS6 (By similarity). Interacts with COP1; this interaction leads to proteasomal degradation (By similarity). Interacts with the 'Thr-369' phosphorylated form of DAPK2 (By similarity). Interacts with PI4KB (By similarity). Interacts with SLITRK1 (By similarity). Interacts with LRRK2; this interaction is dependent on LRRK2 phosphorylation (By similarity).
messages: Nucleus
messages: Secreted
messages: Ubiquitinated. Ubiquitination by RFFL induces proteasomal degradation and indirectly regulates p53/TP53 activation (By similarity).

9940:LOC101116841
gene id: 9940:LOC101116841
uniprot id: A0A6P3EC77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MIP
gene id: 9940:MIP
uniprot id: A0A836D410
uniprot id: Q6J8I9
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Aquaporins contain two tandem repeats each containing two membrane-spanning helices and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). Each tandem repeat contains a loop and a short helix that enter and leave the lipid bilayer on the same side.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Detected in eye lens (at protein level).
messages: Fatty acylated at Met-1 and Lys-238. The acyl modifications, in decreasing order of ion abundance, are: oleoyl (C18:1) > palmitoyl (C16:0) > stearoyl (C18:0) > eicosenoyl (C20:1) > dihomo-gamma-linolenoyl (C20:3) > palmitoleoyl (C16:1) > eicosadienoyl (C20:2).
messages: Homotetramer. Homooctamer formed by head-to-head interaction between homotetramers from adjoining membranes. Interacts with CALM; one CALM molecule interacts with the cytoplasmic domains of two aquaporins, leading to channel closure. Interacts (via C-terminus) with BFSP1 (via C-terminus) in aged lens fiber cells (By similarity).
messages: Membrane
messages: Subject to partial proteolytic cleavage in the eye lens core. Partial proteolysis promotes interactions between tetramers from adjoining membranes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Water channel. Channel activity is down-regulated by CALM when cytoplasmic Ca(2+) levels are increased. May be responsible for regulating the osmolarity of the lens. Interactions between homotetramers from adjoining membranes may stabilize cell junctions in the eye lens core. Plays a role in cell-to-cell adhesion and facilitates gap junction coupling (By similarity).
messages: gap junction

9940:LOC101119916
gene id: 9940:LOC101119916
uniprot id: W5P233
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TSPYL1
gene id: 9940:TSPYL1
uniprot id: A0A6P3EGR8
names: Caution
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPH3AL
gene id: 9940:RPH3AL
uniprot id: A0A6P3E7R5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUDT1
gene id: 9940:NUDT1
uniprot id: A0A835ZQM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Monomer.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C2CD5
gene id: 9940:C2CD5
uniprot id: A0A6P3E3P1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNIH4
gene id: 9940:CNIH4
uniprot id: W5Q3Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9940:NEURL2
gene id: 9940:NEURL2
uniprot id: W5PAB2
names: Subcellular Location Annotation
messages: Cytoplasm

9940:RBBP4
gene id: 9940:RBBP4
uniprot id: A0A6P3E1U0
uniprot id: A0A6P7DI30
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPD1L
gene id: 9940:GPD1L
uniprot id: A0A6P3EPA0
uniprot id: W5Q024
names: Caution
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR1B
gene id: 9940:POLR1B
uniprot id: A0A6P3E2D0
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol I is composed of mobile elements and RPA2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121301
gene id: 9940:LOC101121301
uniprot id: A0A6P3TI37
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYB
gene id: 9940:MYB
uniprot id: W5PZV6
names: Subcellular Location Annotation
messages: Nucleus

9940:DHDH
gene id: 9940:DHDH
uniprot id: A0A6P3ELK2
names: Caution
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAGOHB
gene id: 9940:MAGOHB
uniprot id: W5QIE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus

9940:RARA
gene id: 9940:RARA
uniprot id: W5PXH0
uniprot id: W5PXH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9940:SPAG7
gene id: 9940:SPAG7
uniprot id: W5P5C2
names: Subcellular Location Annotation
messages: Nucleus

9940:ADORA3
gene id: 9940:ADORA3
uniprot id: A0A836ALV2
uniprot id: P35342
uniprot id: W5QED6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Most abundant in lung, spleen and pineal gland. Moderate expression in brain, kidney and testis.
messages: Phosphorylation on Thr-315 and Ser-316 may be crucial for rapid desensitization. Phosphorylation on Thr-315 may be necessary for phosphorylation on Ser-316 to occur.
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BBS9
gene id: 9940:BBS9
uniprot id: A0A6P3E438
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AARD
gene id: 9940:AARD
uniprot id: A0A6P3E7D0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106131
gene id: 9940:LOC101106131
uniprot id: A0A8N7XJH5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP5F1C
gene id: 9940:ATP5F1C
uniprot id: A0A6P3EK28
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105612644
gene id: 9940:LOC105612644
uniprot id: W5PB84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:HSD11B1
gene id: 9940:HSD11B1
uniprot id: P51975
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Controls the reversible conversion of biologically active glucocorticoids such as cortisone to cortisol, and 11-dehydrocorticosterone to corticosterone in the presence of NADP(H) (By similarity). Participates in the corticosteroid receptor-mediated anti-inflammatory response, as well as metabolic and homeostatic processes (By similarity). Plays a role in the secretion of aqueous humor in the eye, maintaining a normotensive, intraocular environment (By similarity). Bidirectional in vitro, predominantly functions as a reductase in vivo, thereby increasing the concentration of active glucocorticoids (By similarity). It has broad substrate specificity, besides glucocorticoids, it accepts other steroid and sterol substrates. Interconverts 7-oxo- and 7-hydroxy-neurosteroids such as 7-oxopregnenolone and 7beta-hydroxypregnenolone, 7-oxodehydroepiandrosterone (3beta-hydroxy-5-androstene-7,17-dione) and 7beta-hydroxydehydroepiandrosterone (3beta,7beta-dihydroxyandrost-5-en-17-one), among others (By similarity). Catalyzes the stereo-specific conversion of the major dietary oxysterol, 7-ketocholesterol (7-oxocholesterol), into the more polar 7-beta-hydroxycholesterol metabolite (By similarity). 7-oxocholesterol is one of the most important oxysterols, it participates in several events such as induction of apoptosis, accumulation in atherosclerotic lesions, lipid peroxidation, and induction of foam cell formation (By similarity). Mediates the 7-oxo reduction of 7-oxolithocholate mainly to chenodeoxycholate, and to a lesser extent to ursodeoxycholate, both in its free form and when conjugated to glycine or taurine, providing a link between glucocorticoid activation and bile acid metabolism (By similarity). Catalyzes the synthesis of 7-beta-25-dihydroxycholesterol from 7-oxo-25-hydroxycholesterol in vitro, which acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity).
messages: Endoplasmic reticulum membrane
messages: Expression in the liver during fetal development increases between day 125 and term, and rises further in the newborn, being highest in the adult liver.
messages: Homodimer.
messages: Liver, kidney, lung, hypothalamus, anterior pituitary and placenta.

9940:ETFRF1
gene id: 9940:ETFRF1
uniprot id: A0A6P3TF54
names: Similarity
messages: Belongs to the complex I LYR family.

9940:KLHL10
gene id: 9940:KLHL10
uniprot id: A0A6P3EIV1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM251
gene id: 9940:TMEM251
uniprot id: A0A6P3TB47
uniprot id: W5PVH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM251 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SSTR1
gene id: 9940:SSTR1
uniprot id: W5Q7Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:OPN1SW
gene id: 9940:OPN1SW
uniprot id: W5NYP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: Photoreceptor inner segment
messages: photoreceptor outer segment

9940:LOC101112223
gene id: 9940:LOC101112223
uniprot id: W5Q2F4
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

9940:LBH
gene id: 9940:LBH
uniprot id: A0A6P3E2I3
uniprot id: W5QEE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LBH family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transcriptional activator.

9940:BOLA1
gene id: 9940:BOLA1
uniprot id: W5QHP1
names: Similarity
messages: Belongs to the BolA/IbaG family.

9940:PROP1
gene id: 9940:PROP1
uniprot id: Q6QME2
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes and caudomedial thyrotropes.

9940:DDAH1
gene id: 9940:DDAH1
uniprot id: W5PY34
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

9940:TMEM147
gene id: 9940:TMEM147
uniprot id: A0A6P3EJL9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOXA9
gene id: 9940:HOXA9
uniprot id: A0A6P3ED29
uniprot id: W5PIW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105601870
gene id: 9940:LOC105601870
uniprot id: A0A836A8K7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112606
gene id: 9940:LOC101112606
uniprot id: A0A836CVN3
uniprot id: W5QGB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC443320
gene id: 9940:LOC443320
uniprot id: P17607
uniprot id: R9QY43
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Expressed in stomach.
messages: Lysozyme C is capable of both hydrolysis and transglycosylation; it shows also a slight esterase activity. It acts rapidly on both peptide-substituted and unsubstituted peptidoglycan, and slowly on chitin oligosaccharides.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
messages: Monomer.
messages: Secreted
messages: The sequence of isozyme 1A/1B/1C is shown.

9940:SEC22B
gene id: 9940:SEC22B
uniprot id: A0A6P3E5M8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9940:FURIN
gene id: 9940:FURIN
uniprot id: Q3BKJ1
names: Similarity
messages: Belongs to the peptidase S8 family.

9940:TMEM100
gene id: 9940:TMEM100
uniprot id: A0A836AB51
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120617
gene id: 9940:LOC101120617
uniprot id: W5Q1B9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9940:MRPS23
gene id: 9940:MRPS23
uniprot id: W5PDS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Mitochondrion

9940:CTLA4
gene id: 9940:CTLA4
uniprot id: O97631
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

9940:RPL27A
gene id: 9940:RPL27A
uniprot id: A0A6P3EHS7
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ORC6
gene id: 9940:ORC6
uniprot id: W5Q251
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

9940:TNFSF18
gene id: 9940:TNFSF18
uniprot id: A0A6P3EI14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114173
gene id: 9940:LOC101114173
uniprot id: A0A836D750
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP1CA
gene id: 9940:PPP1CA
uniprot id: A0A6P3TD53
uniprot id: W5PNV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus
messages: nucleoplasm

9940:CFAP45
gene id: 9940:CFAP45
uniprot id: A0A6P3E4M1
names: Caution
names: Similarity
messages: Belongs to the CFAP45 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LUM
gene id: 9940:LUM
uniprot id: A0A6P3EAC6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

9940:MCCC2
gene id: 9940:MCCC2
uniprot id: W5P5E2
names: Similarity
messages: Belongs to the AccD/PCCB family.

9940:CENPC
gene id: 9940:CENPC
uniprot id: W5PA54
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

9940:PTP4A1
gene id: 9940:PTP4A1
uniprot id: A0A6P3YMX4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9940:NUP54
gene id: 9940:NUP54
uniprot id: A0A6P3E5L9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YIPF6
gene id: 9940:YIPF6
uniprot id: A0A6P3ESG9
uniprot id: W5PZ76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RFC3
gene id: 9940:RFC3
uniprot id: A0A6P3E9E3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL15
gene id: 9940:MRPL15
uniprot id: W5PXD4
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9940:PSAT1
gene id: 9940:PSAT1
uniprot id: A0A6P3E976
names: Caution
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117013
gene id: 9940:LOC101117013
uniprot id: W5NYL2
names: Similarity
messages: Belongs to the peptidase C14A family.

9940:SLC2A5
gene id: 9940:SLC2A5
uniprot id: Q8WMN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
messages: sarcolemma

9940:PLAC8
gene id: 9940:PLAC8
uniprot id: A0A6P3EE64
names: Caution
names: Similarity
messages: Belongs to the cornifelin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDKN1C
gene id: 9940:CDKN1C
uniprot id: B7U177
names: Similarity
messages: Belongs to the CDI family.

9940:ARL2
gene id: 9940:ARL2
uniprot id: C5IWU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

9940:IL17F
gene id: 9940:IL17F
uniprot id: W5PXB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9940:SMCR8
gene id: 9940:SMCR8
uniprot id: A0A6P3EH86
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THUMPD3
gene id: 9940:THUMPD3
uniprot id: A0A835ZNI6
names: Caution
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DPYSL2
gene id: 9940:DPYSL2
uniprot id: W5PJ56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Homotetramer, and heterotetramer with CRMP1, DPYSL3, DPYSL4 or DPYSL5. Interacts through its C-terminus with the C-terminus of CYFIP1/SRA1. Interacts with HTR4. Interacts with CLN6. Interacts with MICALL1.
messages: Plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. May play a role in endocytosis.

9940:HIGD1B
gene id: 9940:HIGD1B
uniprot id: A0A6P3E878
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HBP1
gene id: 9940:HBP1
uniprot id: W5P4R4
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

9940:PDRG1
gene id: 9940:PDRG1
uniprot id: A0A836D0G6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Component of the PAQosome complex which is responsible for the biogenesis of several protein complexes and which consists of R2TP complex members RUVBL1, RUVBL2, RPAP3 and PIH1D1, URI complex members PFDN2, PFDN6, PDRG1, UXT and URI1 as well as ASDURF, POLR2E and DNAAF10/WDR92.
messages: Cytoplasm
messages: May play a role in chaperone-mediated protein folding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SGPL1
gene id: 9940:SGPL1
uniprot id: A0A6P3T696
uniprot id: A0A6P7DH80
names: Caution
names: Similarity
messages: Belongs to the group II decarboxylase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LHX8
gene id: 9940:LHX8
uniprot id: A0A6P3YIT0
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD79A
gene id: 9940:CD79A
uniprot id: W5PEV0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:PAG6
gene id: 9940:PAG6
uniprot id: P83493
names: Developmental Stage
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the peptidase A1 family.
messages: Highly expressed in the placenta between day 60 and day 100 of gestation.
messages: Trophoblast and placental tissue. Produced specifically in the invasive binucleate cells of the placenta.
messages: extracellular space

9940:XPA
gene id: 9940:XPA
uniprot id: A0A6P3E927
uniprot id: W5PNI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPA family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANXA4
gene id: 9940:ANXA4
uniprot id: A0A836AK26
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Zymogen granule membrane

9940:ELMO1
gene id: 9940:ELMO1
uniprot id: A0A6P3TG06
uniprot id: A0A6P7E001
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLL
gene id: 9940:POLL
uniprot id: W5Q4Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

9940:BSG
gene id: 9940:BSG
uniprot id: W5PG64
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

9940:RFTN2
gene id: 9940:RFTN2
uniprot id: W5Q221
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

9940:CLCN4
gene id: 9940:CLCN4
uniprot id: A0A6P7DLA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

9940:ATP6V1G1
gene id: 9940:ATP6V1G1
uniprot id: A0A6P3YJ22
uniprot id: W5P7L2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:ANAPC13
gene id: 9940:ANAPC13
uniprot id: A0A6P3E596
uniprot id: A0A6P3E8F7
names: Caution
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANXA2
gene id: 9940:ANXA2
uniprot id: A0A836D1K4
uniprot id: A2SW69
names: Caution
names: Domain
names: Function
names: Induction
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9.
messages: Detected in myometrium.
messages: Heterotetramer containing 2 light chains of S100A10/p11 and 2 heavy chains of ANXA2/p36 (PubMed:17446234). Interacts with ATP1B1 (By similarity). Interacts with DYSF (By similarity). Interacts with COCH. Interacts (via repeat Annexin 1) with PCSK9 (via the C-terminal domain); the interaction inhibits the degradation of LDLR. Interacts with CEACAM1 (via the cytoplasmic domain); this interaction is regulated by phosphorylation of CEACAM1 (By similarity). Interacts with APPL2 and APPL1; targets APPL2 to endosomes and acting in parallel to RAB5A (By similarity). Interacts with S100A4 (By similarity). May interact with UBAP2 (By similarity). May interact with UBAP2 (By similarity).
messages: ISGylated.
messages: It may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Up-regulated in myometrium upon progesterone treatment.
messages: basement membrane

9940:EIF4B
gene id: 9940:EIF4B
uniprot id: A0A6P3E2S0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STXBP5
gene id: 9940:STXBP5
uniprot id: A0A6P3E6Z6
uniprot id: W5NWF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119740
gene id: 9940:LOC101119740
uniprot id: W5PBY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:MRPL51
gene id: 9940:MRPL51
uniprot id: A0A6P3E3I2
uniprot id: W5PE98
names: Caution
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFS4
gene id: 9940:NDUFS4
uniprot id: A0A6P3EB56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS4 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121607
gene id: 9940:LOC101121607
uniprot id: A0A6P3E807
uniprot id: W5QJ77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HESX1
gene id: 9940:HESX1
uniprot id: W5PZ12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

9940:POU2F1
gene id: 9940:POU2F1
uniprot id: W5PR00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

9940:KLHL5
gene id: 9940:KLHL5
uniprot id: A0A6P3EF15
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SF3B1
gene id: 9940:SF3B1
uniprot id: W5Q1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B1 family.
messages: Nucleus

9940:RTL8C
gene id: 9940:RTL8C
uniprot id: A0A835ZL83
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PCLAF
gene id: 9940:PCLAF
uniprot id: A0A6P3EG06
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:TNFSF15
gene id: 9940:TNFSF15
uniprot id: A0A6P3E7P5
names: Caution
names: Similarity
messages: Belongs to the tumor necrosis factor family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADAMTS4
gene id: 9940:ADAMTS4
uniprot id: W5PIW9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9940:DPY19L1
gene id: 9940:DPY19L1
uniprot id: W5P6T1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9940:PI4K2A
gene id: 9940:PI4K2A
uniprot id: A0A6P3EKQ8
uniprot id: W5PN65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MARK3
gene id: 9940:MARK3
uniprot id: A0A6P3EED7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: dendrite

9940:LOC101110478
gene id: 9940:LOC101110478
uniprot id: A0A6P3TGG7
uniprot id: A0A6P3TIG5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHB
gene id: 9940:PHB
uniprot id: A0A6P3EHB3
uniprot id: A0A6P3TWZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35A5
gene id: 9940:SLC35A5
uniprot id: A0A6P3TNI5
uniprot id: W5QDG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRIM45
gene id: 9940:TRIM45
uniprot id: W5QGE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9940:GOLPH3
gene id: 9940:GOLPH3
uniprot id: W5PRW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9940:RASL12
gene id: 9940:RASL12
uniprot id: A0A6P3YIL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC27A6
gene id: 9940:SLC27A6
uniprot id: W5Q6G3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9940:BPIFA1
gene id: 9940:BPIFA1
uniprot id: A0A075W0S2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
messages: Monomer. Interacts (via N-terminus) with SCNN1B, a subunit of the heterotrimeric epithelial sodium channel (ENaC); this inhibits proteolytic activation of ENaC.
messages: Secreted

9940:CPA1
gene id: 9940:CPA1
uniprot id: W5P5N4
names: Similarity
messages: Belongs to the peptidase M14 family.

9940:PIP4K2B
gene id: 9940:PIP4K2B
uniprot id: A0A6P3EA99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL7L1
gene id: 9940:RPL7L1
uniprot id: A0A6P3ECJ2
uniprot id: W5P205
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SYNPR
gene id: 9940:SYNPR
uniprot id: W5PPT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

9940:LOC101110289
gene id: 9940:LOC101110289
uniprot id: A0A6P3E0E6
uniprot id: W5NY57
names: Caution
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPPC
gene id: 9940:NPPC
uniprot id: P56283
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Degraded by IDE (in vitro).
messages: Hormone which plays a role in endochondral ossification through regulation of cartilaginous growth plate chondrocytes proliferation and differentiation (By similarity). May also be vasoactive and natriuretic. Acts by specifically binding and stimulating NPR2 to produce cGMP. Binds the clearance receptor NPR3 (By similarity).
messages: Secreted

9940:TMEM267
gene id: 9940:TMEM267
uniprot id: W5PFQ6
names: Subcellular Location Annotation
messages: Membrane

9940:RP2
gene id: 9940:RP2
uniprot id: W5PX03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

9940:HS3ST1
gene id: 9940:HS3ST1
uniprot id: A0A6P3E737
uniprot id: A0A6P7E786
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FTL
gene id: 9940:FTL
uniprot id: A0A6P3ECH0
uniprot id: W5PA59
names: Caution
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAM
gene id: 9940:STAM
uniprot id: A0A6P3EBL1
uniprot id: W5PPV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABARAPL2
gene id: 9940:GABARAPL2
uniprot id: A0A6P3YQB0
names: Caution
names: Similarity
messages: Belongs to the ATG8 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJC10
gene id: 9940:DNAJC10
uniprot id: W5Q5P0
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

9940:SCN2A
gene id: 9940:SCN2A
uniprot id: W5P5U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9940:MMP16
gene id: 9940:MMP16
uniprot id: W5PNX8
names: Similarity
messages: Belongs to the peptidase M10A family.

9940:SV2B
gene id: 9940:SV2B
uniprot id: A0A6P3T2A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: synaptic vesicle membrane

9940:TMEM50B
gene id: 9940:TMEM50B
uniprot id: A0A6P3E7K3
uniprot id: A0A6P3YFB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107119
gene id: 9940:LOC101107119
uniprot id: W5PHN8
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:LOC101116381
gene id: 9940:LOC101116381
uniprot id: A0A6P3YUF4
names: Similarity
messages: Belongs to the IAP family.

9940:LOC101114033
gene id: 9940:LOC101114033
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ELOVL1
gene id: 9940:ELOVL1
uniprot id: W5QH76
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9940:SULT2B1
gene id: 9940:SULT2B1
uniprot id: A0A6P3E9X1
uniprot id: W5PQK8
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BLM
gene id: 9940:BLM
uniprot id: W5PTL9
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

9940:NDUFA13
gene id: 9940:NDUFA13
uniprot id: A0A6P3E975
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

9940:INPP5K
gene id: 9940:INPP5K
uniprot id: A0A6P3TRE5
names: Caution
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MIS12
gene id: 9940:MIS12
uniprot id: W5P2A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mis12 family.
messages: Component of the MIS12 complex composed of MIS12, DSN1, NSL1 and PMF1. Also interacts with KNL1, CBX3, CBX5, NDC80 and ZWINT.
messages: kinetochore

9940:NMNAT3
gene id: 9940:NMNAT3
uniprot id: W5PAI8
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9940:GYPC
gene id: 9940:GYPC
uniprot id: A0A6P3E9W4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRWD1
gene id: 9940:GRWD1
uniprot id: W5PQ74
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101118279
gene id: 9940:LOC101118279
uniprot id: A0A6P3TU94
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC30A4
gene id: 9940:SLC30A4
uniprot id: A0A6P3E6A5
uniprot id: W5QIR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL10
gene id: 9940:IL10
uniprot id: Q29408
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-10 family.
messages: Homodimer. Interacts with IL10RA and IL10RB.
messages: Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines including granulocyte-macrophage colony-stimulating factor /GM-CSF, granulocyte colony-stimulating factor/G-CSF, IL-1 alpha, IL-1 beta, IL-6, IL-8 and TNF-alpha. Interferes also with antigen presentation by reducing the expression of MHC-class II and co-stimulatory molecules, thereby inhibiting their ability to induce T cell activation (By similarity). In addition, controls the inflammatory response of macrophages by reprogramming essential metabolic pathways including mTOR signaling (By similarity).
messages: Secreted

9940:LOC101123533
gene id: 9940:LOC101123533
uniprot id: A0A6P7D695
uniprot id: A0A6P7DQI8
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPTSSB
gene id: 9940:SPTSSB
uniprot id: A0A6P3E887
uniprot id: W5PZT5
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:APOBEC1
gene id: 9940:APOBEC1
uniprot id: A0A6P3TFD5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35B1
gene id: 9940:SLC35B1
uniprot id: A0A6P3EDB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPM2
gene id: 9940:TPM2
uniprot id: A0A6P3E0T4
uniprot id: W5PQL4
uniprot id: W5PQL7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:ITGAL
gene id: 9940:ITGAL
uniprot id: Q4QWZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:ASF1B
gene id: 9940:ASF1B
uniprot id: A0A6P3ECG8
uniprot id: W5P8R6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLEC3A
gene id: 9940:CLEC3A
uniprot id: A0A6P3EKW7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAC3
gene id: 9940:TAC3
uniprot id: W5PDI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

9940:BMPR1B
gene id: 9940:BMPR1B
uniprot id: Q9BDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9940:ODF1
gene id: 9940:ODF1
uniprot id: W5Q6T4
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

9940:RNF167
gene id: 9940:RNF167
uniprot id: A0A6P3ED25
uniprot id: A0A6P7EI20
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UCP2
gene id: 9940:UCP2
uniprot id: M4SYY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:STEAP4
gene id: 9940:STEAP4
uniprot id: W5PQD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9940:PANX1
gene id: 9940:PANX1
uniprot id: W5NUS9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9940:NPVF
gene id: 9940:NPVF
uniprot id: B2KKR4
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Expressed in hypothalamus, where it is localized to the dorsomedial hypothalamic nucleus (DMH), paraventricular nucleus (PVN), and to neuronal projections from the PVN to the neurosecretory zone of the median eminence.
messages: Expression moderately increased by a longer photoperiod.
messages: Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPVF blocks morphine-induced analgesia (By similarity). May act in concert with kisspeptin, through opposing affects, to regulate the activity of gonadotropin-releasing hormone (GnRH) neurons across the seasons, leading to an annual change in fertility and the cyclical seasonal transition from non-breeding to breeding season.
messages: Secreted

9940:PNRC2
gene id: 9940:PNRC2
uniprot id: A0A6P3E9D2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GCNT4
gene id: 9940:GCNT4
uniprot id: A0A6P3YJX5
uniprot id: W5PPM1
names: Caution
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GIMD1
gene id: 9940:GIMD1
uniprot id: W5PGZ7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9940:TRIM21
gene id: 9940:TRIM21
uniprot id: A0A836A1R3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FMO2
gene id: 9940:FMO2
uniprot id: W5PS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9940:CCNL2
gene id: 9940:CCNL2
uniprot id: A0A6P3EB75
names: Caution
names: Similarity
messages: Belongs to the cyclin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AQP2
gene id: 9940:AQP2
uniprot id: A0A836D3U5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSNAXIP1
gene id: 9940:TSNAXIP1
uniprot id: A0A6P3TK93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRDM4
gene id: 9940:PRDM4
uniprot id: A0A6P3EB12
uniprot id: W5Q982
names: Caution
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAF9B
gene id: 9940:TAF9B
uniprot id: A0A6P3EHD9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110195
gene id: 9940:LOC101110195
uniprot id: A0A6P3E7S3
uniprot id: W5Q9G3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM168B
gene id: 9940:FAM168B
uniprot id: A0A6P3YJC7
names: Caution
names: Similarity
messages: Belongs to the FAM168 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NAMPT
gene id: 9940:NAMPT
uniprot id: A0A6P3E4P7
uniprot id: W5P316
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL23
gene id: 9940:MRPL23
uniprot id: W5NRD3
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9940:RAB19
gene id: 9940:RAB19
uniprot id: A0A6P3EDA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOL10
gene id: 9940:NOL10
uniprot id: W5Q1Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

9940:POMGNT1
gene id: 9940:POMGNT1
uniprot id: A0A6P3YEX3
uniprot id: W5NW01
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

9940:EXOSC3
gene id: 9940:EXOSC3
uniprot id: A0A836AA42
uniprot id: W5PP23
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLRN1
gene id: 9940:CLRN1
uniprot id: W5P2C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9940:KCNMB4
gene id: 9940:KCNMB4
uniprot id: W5QG40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9940:TASL
gene id: 9940:TASL
uniprot id: A0A6P3TFF0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC100147796
gene id: 9940:LOC100147796
uniprot id: B2MVX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:FAN1
gene id: 9940:FAN1
uniprot id: W5Q3J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

9940:RNF141
gene id: 9940:RNF141
uniprot id: A0A6P3ECW5
uniprot id: A0A6P7EVQ2
names: Caution
names: Function
messages: May be involved in spermatogenesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119670
gene id: 9940:LOC101119670
uniprot id: W5PB51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ZRANB2
gene id: 9940:ZRANB2
uniprot id: A0A6P3E6K0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

9940:LOC101102156
gene id: 9940:LOC101102156
uniprot id: A0A835ZZQ9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX23
gene id: 9940:DDX23
uniprot id: A0A836AA30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAD17
gene id: 9940:RAD17
uniprot id: W5P6J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

9940:ARL6IP6
gene id: 9940:ARL6IP6
uniprot id: A0A6P3E9U4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SCARA5
gene id: 9940:SCARA5
uniprot id: W5PZR9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCARA5 family.
messages: Cell membrane
messages: Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).
messages: Homotrimer.
messages: Membrane

9940:TRIB2
gene id: 9940:TRIB2
uniprot id: A0A6P3E9Q0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL25
gene id: 9940:IL25
uniprot id: A0A6P3TNJ3
uniprot id: E1XUM4
uniprot id: E1XUM5
names: Caution
names: Similarity
messages: Belongs to the IL-17 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1GALT1
gene id: 9940:C1GALT1
uniprot id: W5P439
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Membrane

9940:PCSK1
gene id: 9940:PCSK1
uniprot id: W5Q845
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

9940:LOC101117508
gene id: 9940:LOC101117508
uniprot id: W5PW28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:OTOR
gene id: 9940:OTOR
uniprot id: A0A6P3EK22
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL17
gene id: 9940:MRPL17
uniprot id: W5Q518
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

9940:SNX10
gene id: 9940:SNX10
uniprot id: A0A6P3E453
uniprot id: A0A6P7E1F4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC7A6
gene id: 9940:SLC7A6
uniprot id: A0A836A3C0
uniprot id: W5NZM1
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTC26
gene id: 9940:TTC26
uniprot id: A0A6P3EC63
uniprot id: W5PNF9
names: Caution
names: Similarity
messages: Belongs to the IFT56 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NR1D1
gene id: 9940:NR1D1
uniprot id: B3SV56
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Binds DNA as a monomer or a homodimer (By similarity). Interacts with C1D, NR2E3, SP1 and ZNHIT1 (By similarity). Interacts with OPHN1 (via C-terminus) (By similarity). Interacts with PER2; the interaction associates PER2 to BMAL1 promoter region (By similarity). Interacts with CRY1 (By similarity). Interacts with CCAR2 (By similarity). Interacts with SIAH2 (By similarity). Interacts with FBXW7 and CDK1 (By similarity). Interacts with HUWE1 (By similarity). Interacts with NR0B2 (By similarity). Interacts with NFIL3 (By similarity). Interacts (via domain NR LBD) with HSP90AA1 and HSP90AB1 (By similarity).
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Expressed in all tissues and cell lines examined. Expressed at high levels in some squamous carcinoma cell lines.
messages: Nucleus
messages: Phosphorylated by CSNK1E; phosphorylation enhances its cytoplasmic localization.
messages: Sumoylated by UBE2I, desumoylated by SENP1, and sumoylation is a prerequisite to its ubiquitination.
messages: Transcriptional repressor which coordinates circadian rhythm and metabolic pathways in a heme-dependent manner. Integral component of the complex transcription machinery that governs circadian rhythmicity and forms a critical negative limb of the circadian clock by directly repressing the expression of core clock components BMAL1, CLOCK and CRY1. Also regulates genes involved in metabolic functions, including lipid and bile acid metabolism, adipogenesis, gluconeogenesis and the macrophage inflammatory response. Acts as a receptor for heme which stimulates its interaction with the NCOR1/HDAC3 corepressor complex, enhancing transcriptional repression. Recognizes two classes of DNA response elements within the promoter of its target genes and can bind to DNA as either monomers or homodimers, depending on the nature of the response element. Binds as a monomer to a response element composed of the consensus half-site motif 5'-[A/G]GGTCA-3' preceded by an A/T-rich 5' sequence (RevRE), or as a homodimer to a direct repeat of the core motif spaced by two nucleotides (RevDR-2). Acts as a potent competitive repressor of ROR alpha (RORA) function and regulates the levels of its ligand heme by repressing the expression of PPARGC1A, a potent inducer of heme synthesis. Regulates lipid metabolism by repressing the expression of APOC3 and by influencing the activity of sterol response element binding proteins (SREBPs); represses INSIG2 which interferes with the proteolytic activation of SREBPs which in turn govern the rhythmic expression of enzymes with key functions in sterol and fatty acid synthesis. Regulates gluconeogenesis via repression of G6PC1 and PEPCK and adipocyte differentiation via repression of PPARG. Regulates glucagon release in pancreatic alpha-cells via the AMPK-NAMPT-SIRT1 pathway and the proliferation, glucose-induced insulin secretion and expression of key lipogenic genes in pancreatic-beta cells. Positively regulates bile acid synthesis by increasing hepatic e…
messages: Ubiquitinated, leading to its proteasomal degradation (By similarity). Ubiquitinated by the SCF(FBXW7) complex when phosphorylated by CDK1 leading to its proteasomal degradation (By similarity). Ubiquitinated by SIAH2; leading to its proteasomal degradation (By similarity). Rapidly ubiquitinated in response to inflammatory triggers and sumoylation is a prerequisite to its ubiquitination (By similarity).
messages: Undergoes lysosome-mediated degradation in a time-dependent manner in the liver.
messages: dendrite
messages: dendritic spine

9940:C26H4orf47
gene id: 9940:C26H4orf47
uniprot id: A0A6P3ERJ9
uniprot id: W5PDB3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome

9940:BSP5
gene id: 9940:BSP5
uniprot id: A4GZY3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:NAPB
gene id: 9940:NAPB
uniprot id: W5P625
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9940:ZFP69
gene id: 9940:ZFP69
uniprot id: W5QGA6
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101117534
gene id: 9940:LOC101117534
uniprot id: W5P8W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101110888
gene id: 9940:LOC101110888
uniprot id: W5PX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9940:PMVK
gene id: 9940:PMVK
uniprot id: W5NYK1
names: Subcellular Location Annotation
messages: cytosol

9940:RNF11
gene id: 9940:RNF11
uniprot id: A0A6P3DY87
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRMT13
gene id: 9940:TRMT13
uniprot id: W5Q9B4
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

9940:TARBP2
gene id: 9940:TARBP2
uniprot id: A0A6P3E7K6
uniprot id: W5Q4L1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TARBP2 family.
messages: Cytoplasm
messages: Nucleus
messages: Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
messages: Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9 and PRKRA. Interacts with DICER1, AGO2, MOV10, EIF6 and RPL7A (60S ribosome subunit); they form a large RNA-induced silencing complex (RISC).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:CA3
gene id: 9940:CA3
uniprot id: A0A6P3YN32
uniprot id: W5PUC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

9940:KDM5C
gene id: 9940:KDM5C
uniprot id: A0A6P3THL4
uniprot id: W5PGP0
names: Caution
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBXO32
gene id: 9940:FBXO32
uniprot id: A0A6P3E8Y7
uniprot id: W5PJS7
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RUNDC1
gene id: 9940:RUNDC1
uniprot id: A0A6P3E869
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPS2
gene id: 9940:COPS2
uniprot id: A0A6P3E7V1
uniprot id: W5QIM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN2 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB2
gene id: 9940:PSMB2
uniprot id: A0A6P3DYK1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115331
gene id: 9940:LOC101115331
uniprot id: A0A6P3E4C1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PARP9
gene id: 9940:PARP9
uniprot id: W5QFY8
names: Similarity
messages: Belongs to the ARTD/PARP family.

9940:C15H11orf52
gene id: 9940:C15H11orf52
uniprot id: A0A6P3T4R9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBM3
gene id: 9940:RBM3
uniprot id: A0A6P3EH89
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLITRK6
gene id: 9940:SLITRK6
uniprot id: W5Q6T2
names: Similarity
messages: Belongs to the SLITRK family.

9940:MYOZ3
gene id: 9940:MYOZ3
uniprot id: E5FXR6
names: Similarity
messages: Belongs to the myozenin family.

9940:LAMTOR3
gene id: 9940:LAMTOR3
uniprot id: A0A6P3EEX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PYGM
gene id: 9940:PYGM
uniprot id: A0A835ZTN9
uniprot id: O18751
names: Activity Regulation
names: Caution
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Allosterically regulated through the non-covalent binding of metabolites, being activated by AMP and inhibited by ATP, ADP, and glucose-6-phosphate. The activity is also controlled by post-translational modifications including phosphorylation.
messages: Belongs to the glycogen phosphorylase family.
messages: Homodimer. Homotetramer; to form the enzymatically active phosphorylase A.
messages: Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAU
gene id: 9940:FAU
uniprot id: A0A6P3EK71
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSN2
gene id: 9940:CSN2
uniprot id: P11839
names: Function
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the beta-casein family.
messages: Important role in determination of the surface properties of the casein micelles.
messages: Mammary gland specific. Secreted in milk.
messages: Secreted
messages: The frequency of variant Val-198 is 0.237, 0.244 and 0.176 in Italian breeds Comisana, Sarda and Sopravissana, respectively.

9940:LRRC8C
gene id: 9940:LRRC8C
uniprot id: W5Q1X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9940:LOC101111610
gene id: 9940:LOC101111610
uniprot id: A0A6P3YPM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAG1
gene id: 9940:PAG1
uniprot id: A0A835ZYX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRSS23
gene id: 9940:PRSS23
uniprot id: A0A835ZME5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COQ9
gene id: 9940:COQ9
uniprot id: W5NPZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

9940:LOC101120285
gene id: 9940:LOC101120285
uniprot id: A0A836CR39
names: Caution
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115389
gene id: 9940:LOC101115389
uniprot id: W5PQI4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9940:LOC101119393
gene id: 9940:LOC101119393
uniprot id: A0A836AAU3
uniprot id: W5PIZ0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM225B
gene id: 9940:TMEM225B
uniprot id: A0A6P3EGJ5
uniprot id: A0A6P3TEK7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB3
gene id: 9940:PSMB3
uniprot id: W5PJC2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9940:RPL13A
gene id: 9940:RPL13A
uniprot id: A0A6P3TW05
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107153
gene id: 9940:LOC101107153
uniprot id: A0A6P3DZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9940:PRKAR1A
gene id: 9940:PRKAR1A
uniprot id: A0A6P3CX84
uniprot id: A0A6P7EEY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FMR1NB
gene id: 9940:FMR1NB
uniprot id: A0A6P3ESL4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AHCY
gene id: 9940:AHCY
uniprot id: A0A6P3EBV9
uniprot id: W5PHX1
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC26A4
gene id: 9940:SLC26A4
uniprot id: A0A836D2B9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HMGB2
gene id: 9940:HMGB2
uniprot id: W5Q1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9940:LOC101112339
gene id: 9940:LOC101112339
uniprot id: A0A836A542
uniprot id: W5P2W9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CBX5
gene id: 9940:CBX5
uniprot id: A0A6P3TDF3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPS8
gene id: 9940:EPS8
uniprot id: W5QHG1
names: Similarity
messages: Belongs to the EPS8 family.

9940:CALB1
gene id: 9940:CALB1
uniprot id: A0A6P3ECF0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
messages: Interacts with RANBP9.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FOXR2
gene id: 9940:FOXR2
uniprot id: W5P6A9
names: Subcellular Location Annotation
messages: Nucleus

9940:PHYHIPL
gene id: 9940:PHYHIPL
uniprot id: W5P1X6
names: Similarity
messages: Belongs to the PHYHIP family.

9940:LOC101122444
gene id: 9940:LOC101122444
uniprot id: A0A6P3EGA1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108811
gene id: 9940:LOC101108811
uniprot id: W5QDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:RAB9B
gene id: 9940:RAB9B
uniprot id: W5PJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

9940:CALB2
gene id: 9940:CALB2
uniprot id: A0A6P3EL68
uniprot id: W5P1A7
names: Caution
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRYBB3
gene id: 9940:CRYBB3
uniprot id: A0A6P9FQB5
uniprot id: Q52NW3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VIPAS39
gene id: 9940:VIPAS39
uniprot id: A0A836D0N5
names: Caution
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle

9940:DGAT1
gene id: 9940:DGAT1
uniprot id: A0A6P3CWQ9
uniprot id: A8VJM4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Homodimer or homotetramer; both forms have similar enzymatic activities.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRNB1
gene id: 9940:CHRNB1
uniprot id: A0A6P3E7V7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109397
gene id: 9940:LOC101109397
uniprot id: W5QFP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9940:LOC101103916
gene id: 9940:LOC101103916
uniprot id: A0A6P3YLD4
uniprot id: W5NV66
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGLYRP2
gene id: 9940:PGLYRP2
uniprot id: A0A836D1F9
uniprot id: W5NYF4
names: Caution
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK7
gene id: 9940:CDK7
uniprot id: A0A6P3EDL7
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRC8B
gene id: 9940:LRRC8B
uniprot id: W5Q1V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9940:YTHDC1
gene id: 9940:YTHDC1
uniprot id: A0A6P3TPX4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLD3
gene id: 9940:POLD3
uniprot id: A0A6P3EAH5
uniprot id: W5PKJ6
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM265
gene id: 9940:TMEM265
uniprot id: A0A6P3CYD5
names: Caution
names: Similarity
messages: Belongs to the CD225/Dispanin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MEF2C
gene id: 9940:MEF2C
uniprot id: C0LU83
names: Subcellular Location Annotation
messages: Nucleus

9940:TRIM38
gene id: 9940:TRIM38
uniprot id: A0A6P3T846
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPIB
gene id: 9940:PPIB
uniprot id: A0A6P3EF09
uniprot id: W5QHU9
names: Caution
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPIL3
gene id: 9940:PPIL3
uniprot id: A0A6P3CXJ6
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9940:NCOA2
gene id: 9940:NCOA2
uniprot id: W5P0T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9940:OVAR
gene id: 9940:OVAR
uniprot id: A4ZVZ3
names: Similarity
messages: Belongs to the MHC class I family.

9940:MTRF1L
gene id: 9940:MTRF1L
uniprot id: W5P1H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9940:LACTB2
gene id: 9940:LACTB2
uniprot id: A0A6P3ECA3
names: Caution
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122891
gene id: 9940:LOC101122891
uniprot id: W5PYB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

9940:PAMR1
gene id: 9940:PAMR1
uniprot id: A0A6P3EML3
uniprot id: W5QC79
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM81
gene id: 9940:TMEM81
uniprot id: A0A836A888
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120610
gene id: 9940:LOC101120610
uniprot id: A0A835ZQH6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FXR1
gene id: 9940:FXR1
uniprot id: A0A6P3T288
uniprot id: W5QHL9
names: Caution
names: Similarity
messages: Belongs to the FMR1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PROCA1
gene id: 9940:PROCA1
uniprot id: A0A6P3E9S1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PCCA
gene id: 9940:PCCA
uniprot id: A0A836AAQ5
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMC4
gene id: 9940:PSMC4
uniprot id: W5P8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

9940:SRP54
gene id: 9940:SRP54
uniprot id: A0A6P3TB01
uniprot id: A0A6P3TDG1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMPRSS4
gene id: 9940:TMPRSS4
uniprot id: A0A6P3EM03
uniprot id: W5PDH0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RRN3
gene id: 9940:RRN3
uniprot id: A0A6P3EE45
names: Caution
names: Similarity
messages: Belongs to the RRN3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDCA7L
gene id: 9940:CDCA7L
uniprot id: A0A6P3TFS4
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTBP1
gene id: 9940:PTBP1
uniprot id: A0A6P3ECV0
uniprot id: W5PI44
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107644
gene id: 9940:LOC101107644
uniprot id: A0A835ZMQ7
uniprot id: W5P726
names: Caution
names: Similarity
messages: Belongs to the peptidase S28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK1
gene id: 9940:CDK1
uniprot id: A0A6P3CX96
uniprot id: B7U175
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RRM1
gene id: 9940:RRM1
uniprot id: W5NT70
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

9940:RAB3A
gene id: 9940:RAB3A
uniprot id: B2MVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9940:LOC101109545
gene id: 9940:LOC101109545
uniprot id: W5QFZ8
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9940:FOXB1
gene id: 9940:FOXB1
uniprot id: W5NRY5
names: Subcellular Location Annotation
messages: Nucleus

9940:CXCR4
gene id: 9940:CXCR4
uniprot id: A0A6P9FQV1
uniprot id: W5PLA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell junction
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHM
gene id: 9940:CHM
uniprot id: A0A6P3ESK5
uniprot id: W5NX57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM32A
gene id: 9940:FAM32A
uniprot id: A0A6P3E4F6
uniprot id: W5NQ52
names: Caution
names: Similarity
messages: Belongs to the FAM32 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ELOVL6
gene id: 9940:ELOVL6
uniprot id: W5P2I0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

9940:LOC101108787
gene id: 9940:LOC101108787
uniprot id: A0A6P3DYJ8
uniprot id: A0A6P3TRA7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TOE1
gene id: 9940:TOE1
uniprot id: A0A6P3TIZ1
uniprot id: W5NTY9
names: Caution
names: Similarity
messages: Belongs to the CAF1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MX1
gene id: 9940:MX1
uniprot id: P33237
names: Domain
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: By type I and type III interferons.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Homooligomer. Oligomerizes into multimeric filamentous or ring-like structures by virtue of its stalk domain. Oligomerization is critical for GTPase activity, protein stability, and recognition of viral target structures (By similarity). Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7 (By similarity). Interacts with HSPA5 (By similarity). Interacts with DDX39A and DDX39B (By similarity). Interacts with TUBB/TUBB5.
messages: ISGylated.
messages: Interferon-induced dynamin-like GTPase with antiviral activity.
messages: The C-terminal GTPase effector domain (GED) is involved in oligomerization and viral target recognition.
messages: The middle domain mediates self-assembly and oligomerization.
messages: perinuclear region

9940:GET3
gene id: 9940:GET3
uniprot id: A0A6P3E998
uniprot id: W5PP30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:PCK2
gene id: 9940:PCK2
uniprot id: A0A6P3YMI7
names: Caution
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL11
gene id: 9940:ARL11
uniprot id: A0A6P3TVY6
names: Caution
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105383
gene id: 9940:LOC101105383
uniprot id: A0A6P3TA70
uniprot id: A0A6P7EGA1
names: Caution
names: Similarity
messages: Belongs to the peptidase C12 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN7
gene id: 9940:CLDN7
uniprot id: A0A6P9FQR4
uniprot id: D6R7I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:FAM221A
gene id: 9940:FAM221A
uniprot id: A0A6P3TL98
names: Caution
names: Similarity
messages: Belongs to the FAM221 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NSUN3
gene id: 9940:NSUN3
uniprot id: W5Q7D1
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9940:MTIF3
gene id: 9940:MTIF3
uniprot id: A0A6P7EG41
names: Similarity
messages: Belongs to the IF-3 family.

9940:SPINK1
gene id: 9940:SPINK1
uniprot id: A0A6P3EE96
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GTF2A1
gene id: 9940:GTF2A1
uniprot id: A0A6P3EGG0
uniprot id: W5NY55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERMP1
gene id: 9940:ERMP1
uniprot id: A0A836AMB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CUBN
gene id: 9940:CUBN
uniprot id: W5PJU0
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lysosome membrane
messages: Membrane

9940:DGUOK
gene id: 9940:DGUOK
uniprot id: W5PRH4
names: Similarity
messages: Belongs to the DCK/DGK family.

9940:LOC101106720
gene id: 9940:LOC101106720
uniprot id: A0A6P3EEW7
names: Caution
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS53
gene id: 9940:VPS53
uniprot id: A0A6P3TWM0
uniprot id: W5PQ22
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: trans-Golgi network membrane

9940:FAM126A
gene id: 9940:FAM126A
uniprot id: A0A6P3TCS1
uniprot id: W5PRJ3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:PIFO
gene id: 9940:PIFO
uniprot id: A0A6P3DZ97
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDSS2
gene id: 9940:PDSS2
uniprot id: A0A6P3EFU0
names: Caution
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF3
gene id: 9940:ZNF3
uniprot id: A0A6P3EEB3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC443319
gene id: 9940:LOC443319
uniprot id: P16038
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9940:NMS
gene id: 9940:NMS
uniprot id: W5PUY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

9940:FABP2
gene id: 9940:FABP2
uniprot id: A0A6P3E568
uniprot id: W5Q4A5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:XRCC5
gene id: 9940:XRCC5
uniprot id: A0A836D6X1
uniprot id: W5QDK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TACR1
gene id: 9940:TACR1
uniprot id: W5PTQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9940:CRYAB
gene id: 9940:CRYAB
uniprot id: Q5ENY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Aggregates with homologous proteins, including the small heat shock protein HSPB1, to form large heteromeric complexes. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Interacts with HSPBAP1 and TTN/titin. Interacts with TMEM109. Interacts with DES; binds rapidly during early stages of DES filament assembly and a reduced binding seen in the later stages. Interacts with ATP6V1A and with MTOR, forming a ternary complex (By similarity).
messages: Lysosome
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. In lens epithelial cells, stabilizes the ATP6V1A protein, preventing its degradation by the proteasome (By similarity).
messages: Nucleus
messages: Secreted

9940:ARL4D
gene id: 9940:ARL4D
uniprot id: A0A6P3E873
uniprot id: A0A6P7EGF2
names: Caution
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALDH1A1
gene id: 9940:ALDH1A1
uniprot id: A0A836AM83
uniprot id: P51977
names: Activity Regulation
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Cytosolic dehydrogenase that catalyzes the irreversible oxidation of a wide range of aldehydes to their corresponding carboxylic acid (PubMed:26373694). Functions downstream of retinol dehydrogenases and catalyzes the oxidation of retinaldehyde into retinoic acid, the second step in the oxidation of retinol/vitamin A into retinoic acid. This pathway is crucial to control the levels of retinol and retinoic acid, two important molecules which excess can be teratogenic and cytotoxic (By similarity). Also oxidizes aldehydes resulting from lipid peroxidation like (E)-4-hydroxynon-2-enal/HNE, malonaldehyde and hexanal that form protein adducts and are highly cytotoxic. By participating for instance to the clearance of (E)-4-hydroxynon-2-enal/HNE in the lens epithelium prevents the formation of HNE-protein adducts and lens opacification. Functions also downstream of fructosamine-3-kinase in the fructosamine degradation pathway by catalyzing the oxidation of 3-deoxyglucosone, the carbohydrate product of fructosamine 3-phosphate decomposition, which is itself a potent glycating agent that may react with lysine and arginine side-chains of proteins (By similarity). Has also an aminobutyraldehyde dehydrogenase activity and is probably part of an alternative pathway for the biosynthesis of GABA/4-aminobutanoate in midbrain, thereby playing a role in GABAergic synaptic transmission (By similarity).
messages: Homotetramer (PubMed:26373694, PubMed:9862807). Interacts with PRMT3; the interaction is direct, inhibits ALDH1A1 aldehyde dehydrogenase activity and is independent of the methyltransferase activity of PRMT3 (By similarity).
messages: Inhibited by duocarmycin analogs.
messages: The N-terminus is blocked most probably by acetylation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: axon
messages: cytosol

9940:ABHD2
gene id: 9940:ABHD2
uniprot id: W5PNS1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9940:LOC101121993
gene id: 9940:LOC101121993
uniprot id: A0A6P3E0G2
uniprot id: W5P4H3
names: Caution
names: Similarity
messages: Belongs to the multicopper oxidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EMC3
gene id: 9940:EMC3
uniprot id: A0A6P3EPB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZDHHC4
gene id: 9940:ZDHHC4
uniprot id: A0A6P3ER36
uniprot id: A0A6P3T615
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDK2
gene id: 9940:PDK2
uniprot id: A0A6P3EA71
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNRNPAB
gene id: 9940:HNRNPAB
uniprot id: A0A6P3E9H9
uniprot id: A0A6P3TDU0
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ASPN
gene id: 9940:ASPN
uniprot id: A0A6P3E0K4
uniprot id: W5PEI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:TEKT1
gene id: 9940:TEKT1
uniprot id: W5NQ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9940:ANGEL2
gene id: 9940:ANGEL2
uniprot id: A0A835ZXX2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MFNG
gene id: 9940:MFNG
uniprot id: W5QD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9940:ATP1B4
gene id: 9940:ATP1B4
uniprot id: W5PU88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9940:DPEP3
gene id: 9940:DPEP3
uniprot id: A0A6P3EFZ1
uniprot id: W5NZA0
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SRP68
gene id: 9940:SRP68
uniprot id: W5PEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

9940:LIN54
gene id: 9940:LIN54
uniprot id: A0A6P3EAI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

9940:LOC101123383
gene id: 9940:LOC101123383
uniprot id: W5PVU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101106395
gene id: 9940:LOC101106395
uniprot id: A0A6P3E8Z9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L-xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NFX1
gene id: 9940:NFX1
uniprot id: A0A6P3E5S0
uniprot id: W5PIB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB18
gene id: 9940:RAB18
uniprot id: W5Q3W4
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

9940:LOC101103279
gene id: 9940:LOC101103279
uniprot id: W5P743
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLMP family.
messages: Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

9940:C1H1orf54
gene id: 9940:C1H1orf54
uniprot id: A0A6P3TNG8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM202
gene id: 9940:TMEM202
uniprot id: A0A6P3EFI1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTC1
gene id: 9940:TTC1
uniprot id: A0A6P3ED65
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFA11
gene id: 9940:NDUFA11
uniprot id: A0A8N7XJ91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA11 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DLGAP5
gene id: 9940:DLGAP5
uniprot id: W5QIW2
names: Similarity
messages: Belongs to the SAPAP family.

9940:PSMD2
gene id: 9940:PSMD2
uniprot id: A0A6P3E826
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S2 family.
messages: Binds to the intracellular domain of tumor necrosis factor type 1 receptor. The binding domain of TRAP1 and TRAP2 resides outside the death domain of TNFR1.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBR2
gene id: 9940:UBR2
uniprot id: A0A6P3EPS0
uniprot id: W5P0B8
names: Caution
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9940:AGPAT3
gene id: 9940:AGPAT3
uniprot id: A0A6P3YFK2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ESF1
gene id: 9940:ESF1
uniprot id: W5PND6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

9940:STOML1
gene id: 9940:STOML1
uniprot id: A0A6P3EBV8
uniprot id: W5P2G0
names: Caution
names: Similarity
messages: Belongs to the band 7/mec-2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GNAT1
gene id: 9940:GNAT1
uniprot id: A0A6P3YSC3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:N4BP3
gene id: 9940:N4BP3
uniprot id: W5P7Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the N4BP3 family.
messages: Cytoplasmic vesicle
messages: Vesicle
messages: axon
messages: dendrite

9940:SGCE
gene id: 9940:SGCE
uniprot id: W5NWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: Golgi apparatus
messages: cytoskeleton
messages: dendrite
messages: sarcolemma

9940:MFSD1
gene id: 9940:MFSD1
uniprot id: A0A6P3T3L1
uniprot id: A0A6P7D7N4
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ELAC1
gene id: 9940:ELAC1
uniprot id: A0A836CS97
names: Caution
names: Subunit
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABRE
gene id: 9940:GABRE
uniprot id: A0A6P3ESW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC8A1
gene id: 9940:SLC8A1
uniprot id: A0A6P3TAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9940:PSAP
gene id: 9940:PSAP
uniprot id: W5PAJ2
names: Subcellular Location Annotation
messages: Secreted

9940:LOC101102327
gene id: 9940:LOC101102327
uniprot id: A0A6P3YPW3
uniprot id: W5NSR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP7B
gene id: 9940:ATP7B
uniprot id: Q9XT50
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.
messages: Each HMA domain can bind a copper ion, they are tightly packed and closely interact with each other. Wild-type ATP7B can usually be loaded with an average 5.5 copper atoms per molecule (By similarity).
messages: Late endosome
messages: Monomer. Interacts with COMMD1/MURR1 (By similarity). Interacts with DCTN4, in a copper-dependent manner (By similarity). Interacts with ATOX1 (By similarity). Interacts (via C-terminus) with ZBTB16/PLZF (By similarity).
messages: The short isoform is expressed primarily in the liver with lower levels present in the intestine, hypothalamus and ovary. The long isoform is expressed in the liver.
messages: trans-Golgi network membrane

9940:GJB2
gene id: 9940:GJB2
uniprot id: A0A836CYR6
uniprot id: P46691
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: A hemichannel or connexon is composed of a hexamer of connexins. A functional gap junction is formed by the apposition of two hemichannels (By similarity). Forms heteromeric channels with GJB4. Interacts with CNST (By similarity).
messages: Belongs to the connexin family.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: Structural component of gap junctions (By similarity). Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane (By similarity). Small molecules and ions diffuse from one cell to a neighboring cell via the central pore (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: gap junction

9940:CYTH1
gene id: 9940:CYTH1
uniprot id: A0A6P3TIF4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD5
gene id: 9940:PSMD5
uniprot id: W5P6M2
names: Similarity
messages: Belongs to the proteasome subunit S5B/HSM3 family.

9940:LOC101104931
gene id: 9940:LOC101104931
uniprot id: W5PBS3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SLC11A1
gene id: 9940:SLC11A1
uniprot id: P49280
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes (By similarity).
messages: Membrane

9940:PON2
gene id: 9940:PON2
uniprot id: B2LSM4
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

9940:CEP44
gene id: 9940:CEP44
uniprot id: W5Q157
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

9940:MRPS21
gene id: 9940:MRPS21
uniprot id: A0A6P3E725
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

9940:TAC1
gene id: 9940:TAC1
uniprot id: A0A6P9FQB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted
messages: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.

9940:TMEM200A
gene id: 9940:TMEM200A
uniprot id: A0A6P3E6T8
uniprot id: A0A6P3TJJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GBX2
gene id: 9940:GBX2
uniprot id: W5QCV0
names: Subcellular Location Annotation
messages: Nucleus

9940:KRT23
gene id: 9940:KRT23
uniprot id: W5Q1S9
names: Similarity
messages: Belongs to the intermediate filament family.

9940:RORA
gene id: 9940:RORA
uniprot id: A0A0F7YLU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9940:SNW1
gene id: 9940:SNW1
uniprot id: A0A6P3EFH2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104501
gene id: 9940:LOC101104501
uniprot id: W5NXE5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:METTL16
gene id: 9940:METTL16
uniprot id: W5Q2Q4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

9940:PCYT1A
gene id: 9940:PCYT1A
uniprot id: A0A6P3T5H2
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

9940:TMED10
gene id: 9940:TMED10
uniprot id: A0A6P3EBE7
uniprot id: W5NUK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:B4GALNT2
gene id: 9940:B4GALNT2
uniprot id: M1LF60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Membrane

9940:C1QTNF7
gene id: 9940:C1QTNF7
uniprot id: A0A6P3EE94
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTR
gene id: 9940:MTR
uniprot id: W5P0S6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

9940:DCTN2
gene id: 9940:DCTN2
uniprot id: A0A6P3E7U9
names: Caution
names: Function
names: Similarity
messages: Belongs to the dynactin subunit 2 family.
messages: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MDFI
gene id: 9940:MDFI
uniprot id: A0A835ZYA6
uniprot id: W5NW48
names: Caution
names: Similarity
messages: Belongs to the MDFI family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NAALADL1
gene id: 9940:NAALADL1
uniprot id: A0A6P3EFI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RTF2
gene id: 9940:RTF2
uniprot id: W5Q9W6
names: Similarity
names: Subunit
messages: Belongs to the rtf2 family.
messages: Interacts with DDI2; probably also interacts with DDI1.

9940:TLCD2
gene id: 9940:TLCD2
uniprot id: W5PWN3
names: Subcellular Location Annotation
messages: Membrane

9940:TM4SF1
gene id: 9940:TM4SF1
uniprot id: W5P478
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9940:ST3GAL4
gene id: 9940:ST3GAL4
uniprot id: A0A6P9FQD0
uniprot id: A8E1W0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC17A1
gene id: 9940:SLC17A1
uniprot id: W5NWH9
names: Subcellular Location Annotation
messages: Membrane

9940:NIT2
gene id: 9940:NIT2
uniprot id: W5Q9C4
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

9940:GOT1
gene id: 9940:GOT1
uniprot id: A0A6P3EKR0
uniprot id: W5PS88
names: Caution
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HIBCH
gene id: 9940:HIBCH
uniprot id: A0A6P3E146
uniprot id: W5Q437
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NKAPL
gene id: 9940:NKAPL
uniprot id: W5PH23
names: Similarity
messages: Belongs to the NKAP family.

9940:WDR19
gene id: 9940:WDR19
uniprot id: A0A6P3E6U2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MDH2
gene id: 9940:MDH2
uniprot id: W5PW05
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

9940:RGS4
gene id: 9940:RGS4
uniprot id: D3U1F9
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.

9940:EXOSC10
gene id: 9940:EXOSC10
uniprot id: A0A6P3EI24
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119566
gene id: 9940:LOC101119566
uniprot id: W5NR87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CAT
gene id: 9940:CAT
uniprot id: A0A6P3EKV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POFUT1
gene id: 9940:POFUT1
uniprot id: W5NZC9
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

9940:EHD4
gene id: 9940:EHD4
uniprot id: W5QGX7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9940:SLC4A1
gene id: 9940:SLC4A1
uniprot id: W5PD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
messages: Membrane

9940:LATS1
gene id: 9940:LATS1
uniprot id: A0A6P3EG36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CP
gene id: 9940:CP
uniprot id: Q9XT27
uniprot id: W5P4S0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the multicopper oxidase family.
messages: Binds 6 Cu cations per monomer.
messages: Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (By similarity).
messages: Expressed by the liver and secreted in plasma. Also expressed in the hypothalamus, spleen and uterus. No expression in the cortex, heart, intestine or kidney.
messages: Secreted

9940:MRPS12
gene id: 9940:MRPS12
uniprot id: A0A6P3ELE7
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

9940:HSD17B2
gene id: 9940:HSD17B2
uniprot id: I1W6S6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:CCL21
gene id: 9940:CCL21
uniprot id: W5PH56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9940:LOC101115926
gene id: 9940:LOC101115926
uniprot id: K4P217
uniprot id: W5P1B4
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9940:FABP6
gene id: 9940:FABP6
uniprot id: A0A6P3E4Z9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP11B
gene id: 9940:ATP11B
uniprot id: W5QHL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9940:S1PR1
gene id: 9940:S1PR1
uniprot id: A0A836AFT5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPHX1
gene id: 9940:EPHX1
uniprot id: A0A6P3YPB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:TSPAN14
gene id: 9940:TSPAN14
uniprot id: A0A6P3EGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:PFKFB4
gene id: 9940:PFKFB4
uniprot id: W5Q914
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9940:LOC101104465
gene id: 9940:LOC101104465
uniprot id: A0A6P3EFI4
uniprot id: W5P755
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNUPN
gene id: 9940:SNUPN
uniprot id: A0A835ZQ30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TFPI
gene id: 9940:TFPI
uniprot id: W5Q4W4
names: Subcellular Location Annotation
messages: Secreted

9940:GMPR2
gene id: 9940:GMPR2
uniprot id: A0A836A2R5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DOLK
gene id: 9940:DOLK
uniprot id: A0A6P3E2B5
uniprot id: W5QCP5
names: Caution
names: Similarity
messages: Belongs to the polyprenol kinase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110717
gene id: 9940:LOC101110717
uniprot id: A0A6P3YPJ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCT8
gene id: 9940:CCT8
uniprot id: A0A6P3E4Q7
uniprot id: W5PYM5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium basal body

9940:TMCO2
gene id: 9940:TMCO2
uniprot id: A0A6P3DY40
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35A1
gene id: 9940:SLC35A1
uniprot id: A0A6P3EGX7
uniprot id: W5PU48
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYBL1
gene id: 9940:MYBL1
uniprot id: A0A6P3EHF6
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACVR1
gene id: 9940:ACVR1
uniprot id: A0A6P7DPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9940:ARL4A
gene id: 9940:ARL4A
uniprot id: A0A6P3TKW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATIC
gene id: 9940:ATIC
uniprot id: W5QDE5
names: Similarity
messages: Belongs to the PurH family.

9940:YOD1
gene id: 9940:YOD1
uniprot id: A0A6P3E8I1
uniprot id: W5PAI3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAF1
gene id: 9940:PAF1
uniprot id: A0A836A227
uniprot id: W5P7T3
names: Caution
names: Similarity
messages: Belongs to the PAF1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ID2
gene id: 9940:ID2
uniprot id: A0A6P3E9N8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM9
gene id: 9940:TMEM9
uniprot id: A0A6P3YLQ2
names: Caution
names: Similarity
messages: Belongs to the TMEM9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HMGCL
gene id: 9940:HMGCL
uniprot id: W5PAS5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

9940:AASDHPPT
gene id: 9940:AASDHPPT
uniprot id: A0A6P3YMS5
uniprot id: W5NX68
names: Caution
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DBNDD1
gene id: 9940:DBNDD1
uniprot id: A0A836A2Y6
uniprot id: W5Q0S5
names: Caution
names: Similarity
messages: Belongs to the dysbindin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106376
gene id: 9940:LOC101106376
uniprot id: A0A6P3YEW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

9940:SNRNP40
gene id: 9940:SNRNP40
uniprot id: A0A6P3E242
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118736
gene id: 9940:LOC101118736
uniprot id: A0A835ZMU2
uniprot id: W5Q7R3
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HES5
gene id: 9940:HES5
uniprot id: A0A6P3E8R6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TLR10
gene id: 9940:TLR10
uniprot id: B5DC95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9940:DHX15
gene id: 9940:DHX15
uniprot id: A0A6P3EDW7
uniprot id: W5P7B4
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC42
gene id: 9940:CDC42
uniprot id: M4WED3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

9940:TOMM70
gene id: 9940:TOMM70
uniprot id: A0A6P3DZJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL1RN
gene id: 9940:IL1RN
uniprot id: M4WHI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Anti-inflammatory antagonist of interleukin-1 family of proinflammatory cytokines such as interleukin-1beta/IL1B and interleukin-1alpha/IL1A. Protects from immune dysregulation and uncontrolled systemic inflammation triggered by IL1 for a range of innate stimulatory agents such as pathogens.
messages: Belongs to the IL-1 family.
messages: Secreted

9940:SNRPB
gene id: 9940:SNRPB
uniprot id: A0A6P3YL13
uniprot id: W5P9V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDRG3
gene id: 9940:NDRG3
uniprot id: A0A6P3EBX6
uniprot id: A0A6P3TMS0
names: Caution
names: Similarity
messages: Belongs to the NDRG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPB41L5
gene id: 9940:EPB41L5
uniprot id: W5PTM7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

9940:LOC101117706
gene id: 9940:LOC101117706
uniprot id: A0A6P3TBY5
uniprot id: W5PXU4
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NSFL1C
gene id: 9940:NSFL1C
uniprot id: A0A6P3EBT8
uniprot id: W5QB13
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Golgi stack
messages: Part of a ternary complex containing STX5A, NSFL1C and VCP. NSFL1C forms a homotrimer that binds to one end of a VCP homohexamer. The complex binds to membranes enriched in phosphatidylethanolamine-containing lipids and promotes Golgi membrane fusion. Interaction with VCIP135 leads to dissociation of the complex via ATP hydrolysis by VCP. Binds ubiquitin and mono-ubiquitinated proteins via its N-terminal UBA-like domain when bound to VCP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFA1
gene id: 9940:NDUFA1
uniprot id: A0A6P9FRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9940:CXCL9
gene id: 9940:CXCL9
uniprot id: A0A836A218
uniprot id: W5Q4X6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCP1
gene id: 9940:MCP1
uniprot id: P80931
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the peptidase S1 family. Granzyme subfamily.
messages: Cytoplasmic granule
messages: Has a chymotrypsin-like and trypsin-like activity.
messages: Mucosal mast cells.
messages: Secreted

9940:CEL
gene id: 9940:CEL
uniprot id: W5P5Z7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9940:NTF3
gene id: 9940:NTF3
uniprot id: W5PGZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

9940:AARS1
gene id: 9940:AARS1
uniprot id: W5P5H4
names: Cofactor
names: Domain
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: ISGylated.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

9940:CRH
gene id: 9940:CRH
uniprot id: W5Q7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9940:LPAR4
gene id: 9940:LPAR4
uniprot id: A0A6P3ES60
uniprot id: W5P7T0
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121414
gene id: 9940:LOC101121414
uniprot id: W5QBI2
names: Similarity
messages: Belongs to the apolipoprotein L family.

9940:PMAIP1
gene id: 9940:PMAIP1
uniprot id: A0A6P3EDZ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC37A4
gene id: 9940:SLC37A4
uniprot id: A0A836CVW7
uniprot id: W5PS34
uniprot id: W5PS35
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRELID1
gene id: 9940:PRELID1
uniprot id: A0A6P3ECS1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL11RA
gene id: 9940:IL11RA
uniprot id: A0A6P3E7W3
uniprot id: A0A6P3TBS7
names: Caution
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108747
gene id: 9940:LOC101108747
uniprot id: A0A6P3TGP4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAHD2A
gene id: 9940:FAHD2A
uniprot id: A0A836A9M9
names: Caution
names: Similarity
messages: Belongs to the FAH family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITGAM
gene id: 9940:ITGAM
uniprot id: A2TJJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:LOC101111060
gene id: 9940:LOC101111060
uniprot id: W5QE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

9940:TMEM107
gene id: 9940:TMEM107
uniprot id: A0A6P3ED64
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBM27
gene id: 9940:RBM27
uniprot id: A0A6P3EE89
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMIM14
gene id: 9940:SMIM14
uniprot id: A0A6P3EF19
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCBP1
gene id: 9940:NCBP1
uniprot id: A0A6P3E154
uniprot id: W5PNL4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFS3
gene id: 9940:NDUFS3
uniprot id: A0A6P3EKX5
names: Caution
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALCAM
gene id: 9940:ALCAM
uniprot id: W5QBM4
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

9940:SLC35B4
gene id: 9940:SLC35B4
uniprot id: A0A836A5H4
uniprot id: W5PB80
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMA1
gene id: 9940:PSMA1
uniprot id: W5P9U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9940:LOC101103726
gene id: 9940:LOC101103726
uniprot id: W5NR12
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9940:LOC101106925
gene id: 9940:LOC101106925
uniprot id: A0A6P3EB73
uniprot id: W5QHS2
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDR59
gene id: 9940:WDR59
uniprot id: A0A6P3EKV7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:B4GALT6
gene id: 9940:B4GALT6
uniprot id: A0A6P3EL23
uniprot id: W5P8J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103029
gene id: 9940:LOC101103029
uniprot id: W5PZQ4
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

9940:EIF4ENIF1
gene id: 9940:EIF4ENIF1
uniprot id: W5PLR2
names: Subcellular Location Annotation
messages: Cytoplasm

9940:FAM76B
gene id: 9940:FAM76B
uniprot id: A0A6P3ECQ0
names: Caution
names: Similarity
messages: Belongs to the FAM76 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110467
gene id: 9940:LOC101110467
uniprot id: A0A6P3TTC7
uniprot id: W5Q9H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9940:DCTN3
gene id: 9940:DCTN3
uniprot id: A0A6P3E5R0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRYGS
gene id: 9940:CRYGS
uniprot id: W5QH67
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9940:MRPL24
gene id: 9940:MRPL24
uniprot id: A0A6P3TVI1
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STMN1
gene id: 9940:STMN1
uniprot id: A0A6P3E1Y4
names: Similarity
messages: Belongs to the stathmin family.

9940:ADGRG6
gene id: 9940:ADGRG6
uniprot id: W5NTH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:CRISP2
gene id: 9940:CRISP2
uniprot id: D6PX63
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:PTGS1
gene id: 9940:PTGS1
uniprot id: P05979
names: Activity Regulation
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Conversion of arachidonate to prostaglandin H2 is mediated by 2 different isozymes: the constitutive PTGS1 and the inducible PTGS2. PTGS1 is expressed constitutively and generally produces prostanoids acutely in response to hormonal stimuli to fine-tune physiological processes requiring instantaneous, continuous regulation (e.g. hemostasis). PTGS2 is inducible and typically produces prostanoids that mediate responses to physiological stresses such as infection and inflammation.
messages: Dual cyclooxygenase and peroxidase in the biosynthesis pathway of prostanoids, a class of C20 oxylipins mainly derived from arachidonate, with a particular role in the inflammatory response. The cyclooxygenase activity oxygenates arachidonate (AA, C20:4(n-6)) to the hydroperoxy endoperoxide prostaglandin G2 (PGG2), and the peroxidase activity reduces PGG2 to the hydroxy endoperoxide PGH2, the precursor of all 2-series prostaglandins and thromboxanes. This complex transformation is initiated by abstraction of hydrogen at carbon 13 (with S-stereochemistry), followed by insertion of molecular O2 to form the endoperoxide bridge between carbon 9 and 11 that defines prostaglandins. The insertion of a second molecule of O2 (bis-oxygenase activity) yields a hydroperoxy group in PGG2 that is then reduced to PGH2 by two electrons (PubMed:7947975). Involved in the constitutive production of prostanoids in particular in the stomach and platelets. In gastric epithelial cells, it is a key step in the generation of prostaglandins, such as prostaglandin E2 (PGE2), which plays an important role in cytoprotection. In platelets, it is involved in the generation of thromboxane A2 (TXA2), which promotes platelet activation and aggregation, vasoconstriction and proliferation of vascular smooth muscle cells (PubMed:10438452).
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Microsome membrane
messages: PTGS1 and PTGS2 are the targets of nonsteroidal anti-inflammatory drugs (NSAIDs) including aspirin and ibuprofen. Aspirin is able to produce an irreversible inactivation of the enzyme through a serine acetylation. Inhibition of the PGHSs with NSAIDs acutely reduces inflammation, pain, and fever, and long-term use of these drugs reduces fatal thrombotic events, as well as the development of colon cancer and Alzheimer's disease. PTGS2 is the principal isozyme responsible for production of inflammatory prostaglandins. New generation PTGSs inhibitors strive to be selective for PTGS2, to avoid side effects such as gastrointestinal complications and ulceration.
messages: The conversion of arachidonate to prostaglandin H2 is a 2 step reaction: a cyclooxygenase (COX) reaction which converts arachidonate to prostaglandin G2 (PGG2) and a peroxidase reaction in which PGG2 is reduced to prostaglandin H2 (PGH2). The cyclooxygenase reaction occurs in a hydrophobic channel in the core of the enzyme. The peroxidase reaction occurs at a heme-containing active site located near the protein surface. The nonsteroidal anti-inflammatory drugs (NSAIDs) binding site corresponds to the cyclooxygenase active site.
messages: The cyclooxygenase activity is inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs) including ibuprofen, flurbiprofen, ketoprofen, naproxen, flurbiprofen, anirolac, fenclofenac and diclofenac.

9940:FOXO3
gene id: 9940:FOXO3
uniprot id: A0A6P3CXG2
names: Subcellular Location Annotation
messages: Nucleus

9940:LSM14A
gene id: 9940:LSM14A
uniprot id: A0A6P3EFJ6
uniprot id: W5P2Y8
names: Caution
names: Similarity
messages: Belongs to the LSM14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRNA1
gene id: 9940:CHRNA1
uniprot id: W5NQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:TMEM89
gene id: 9940:TMEM89
uniprot id: A0A6P3EEM9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP1B3
gene id: 9940:ATP1B3
uniprot id: A0A6P7EUT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9940:PTTG1
gene id: 9940:PTTG1
uniprot id: A0A836ADD8
uniprot id: W5PVM2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERGIC3
gene id: 9940:ERGIC3
uniprot id: A0A6P3EBW9
uniprot id: W5PVC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NLRP1
gene id: 9940:NLRP1
uniprot id: W5NXB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NLRP family.
messages: Inflammasome
messages: cytosol

9940:LOC101104151
gene id: 9940:LOC101104151
uniprot id: W5PZ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9940:WDR55
gene id: 9940:WDR55
uniprot id: A0A6P3E4T7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR55 family.
messages: Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:MRPL1
gene id: 9940:MRPL1
uniprot id: W5Q8S0
names: Subcellular Location Annotation
messages: Mitochondrion

9940:ALDH1A2
gene id: 9940:ALDH1A2
uniprot id: A0A6P3E685
uniprot id: W5QI69
names: Caution
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IZUMO1
gene id: 9940:IZUMO1
uniprot id: C6ZEB0
names: Similarity
messages: Belongs to the Izumo family.

9940:HOMER1
gene id: 9940:HOMER1
uniprot id: W5Q772
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9940:NMUR2
gene id: 9940:NMUR2
uniprot id: W5PHQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9940:LOC101103182
gene id: 9940:LOC101103182
uniprot id: W5P456
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9940:IL21
gene id: 9940:IL21
uniprot id: H6SGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

9940:CLDN6
gene id: 9940:CLDN6
uniprot id: W5PLQ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9940:MGA
gene id: 9940:MGA
uniprot id: W5QGR9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:ALX1
gene id: 9940:ALX1
uniprot id: W5Q1B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9940:MTNR1A
gene id: 9940:MTNR1A
uniprot id: P48040
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

9940:PRPF18
gene id: 9940:PRPF18
uniprot id: A0A6P3TJ94
uniprot id: W5P8D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9940:BCAT1
gene id: 9940:BCAT1
uniprot id: Q9GKM4
uniprot id: W5QFT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
messages: Cytoplasm
messages: Expressed in muscles.
messages: Homodimer.

9940:TNFSF10
gene id: 9940:TNFSF10
uniprot id: W5QHU1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Homotrimer.
messages: Membrane
messages: Secreted

9940:SLC25A4
gene id: 9940:SLC25A4
uniprot id: B2MVW8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9940:EEF2
gene id: 9940:EEF2
uniprot id: A0A6P3TM14
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

9940:LOC105612015
gene id: 9940:LOC105612015
uniprot id: A0A6P3TIB2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSD17B12
gene id: 9940:HSD17B12
uniprot id: A0A6P3ED76
uniprot id: A0A6P7D784
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLAC1
gene id: 9940:PLAC1
uniprot id: A0A6P3T7J3
uniprot id: W5PIH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

9940:SLC35G2
gene id: 9940:SLC35G2
uniprot id: A0A836AQN8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUDT9
gene id: 9940:NUDT9
uniprot id: A0A6P9FQS2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105612194
gene id: 9940:LOC105612194
uniprot id: W5PHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:VSIR
gene id: 9940:VSIR
uniprot id: A0A6P3EGQ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DAG1
gene id: 9940:DAG1
uniprot id: W5PVZ9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: cytoskeleton
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

9940:ADGRF1
gene id: 9940:ADGRF1
uniprot id: W5PPK1
names: Subcellular Location Annotation
messages: Membrane

9940:SAP130
gene id: 9940:SAP130
uniprot id: W5Q362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

9940:FCGRT
gene id: 9940:FCGRT
uniprot id: A0A6P7EP66
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EPGN
gene id: 9940:EPGN
uniprot id: W5PZZ5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:SLITRK3
gene id: 9940:SLITRK3
uniprot id: W5PZM0
names: Similarity
messages: Belongs to the SLITRK family.

9940:LOC101109827
gene id: 9940:LOC101109827
uniprot id: A0A6P3TBU9
uniprot id: A0A6P7EVV9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZC3H15
gene id: 9940:ZC3H15
uniprot id: A0A6P3E660
uniprot id: W5Q562
names: Caution
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105044
gene id: 9940:LOC101105044
uniprot id: W5PAC2
names: Similarity
messages: Belongs to the serpin family.

9940:DDX41
gene id: 9940:DDX41
uniprot id: A0A6P3EDW3
uniprot id: W5P6C3
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KATNA1
gene id: 9940:KATNA1
uniprot id: A0A6P3E8T1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

9940:HOXB13
gene id: 9940:HOXB13
uniprot id: W5PA69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9940:SFTA2
gene id: 9940:SFTA2
uniprot id: A0A6P3ECT0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMPX
gene id: 9940:SMPX
uniprot id: A0A6P3EMQ3
names: Function
names: Similarity
messages: Belongs to the SMPX family.
messages: Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.

9940:CCNE1
gene id: 9940:CCNE1
uniprot id: W5P1P9
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

9940:TMEM252
gene id: 9940:TMEM252
uniprot id: A0A6P3E0W5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALOX12B
gene id: 9940:ALOX12B
uniprot id: W5QBJ9
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:CACNG6
gene id: 9940:CACNG6
uniprot id: W5NS49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.

9940:LOC101112287
gene id: 9940:LOC101112287
uniprot id: W5PGR4
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9940:SAYSD1
gene id: 9940:SAYSD1
uniprot id: A0A6P3EER9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ABCG2
gene id: 9940:ABCG2
uniprot id: Q009B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

9940:CLUAP1
gene id: 9940:CLUAP1
uniprot id: W5NUY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLUAP1 family.
messages: cilium

9940:ACOT8
gene id: 9940:ACOT8
uniprot id: A0A6P3EC02
uniprot id: W5PA22
names: Caution
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAP2
gene id: 9940:TAP2
uniprot id: A0A6P7D6F7
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

9940:ANGPTL3
gene id: 9940:ANGPTL3
uniprot id: A0A6P3E416
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRN1
gene id: 9940:LRRN1
uniprot id: A0A6P3EPC8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHAG
gene id: 9940:RHAG
uniprot id: W5PRU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9940:TCEAL8
gene id: 9940:TCEAL8
uniprot id: A0A835ZPS0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TXNL4A
gene id: 9940:TXNL4A
uniprot id: A0A6P3EFY3
uniprot id: W5P1U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ST3GAL6
gene id: 9940:ST3GAL6
uniprot id: A0A6P3TUJ5
uniprot id: W5Q8L9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAI2
gene id: 9940:DNAI2
uniprot id: A0A6P3TLF9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZMYND10
gene id: 9940:ZMYND10
uniprot id: W5PIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ZMYND10 family.
messages: Dynein axonemal particle
messages: Plays a role in axonemal structure organization and motility. Involved in axonemal pre-assembly of inner and outer dynein arms (IDA and ODA, respectively) for proper axoneme building for cilia motility. May act by indirectly regulating transcription of dynein proteins.
messages: centriolar satellite

9940:TYR
gene id: 9940:TYR
uniprot id: A7LK11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9940:MTF1
gene id: 9940:MTF1
uniprot id: A0A836D6P9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C5H5orf24
gene id: 9940:C5H5orf24
uniprot id: W5PUW6
names: Similarity
messages: Belongs to the UPF0461 family.

9940:BBS5
gene id: 9940:BBS5
uniprot id: A0A6P3E8L7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BBS5 family.
messages: Membrane
messages: Part of BBSome complex, that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8/TTC8, BBS9 and BBIP10.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for BBSome complex ciliary localization but not for the proper complex assembly.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centriolar satellite
messages: cilium membrane

9940:CXCL16
gene id: 9940:CXCL16
uniprot id: A0A6P7EKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Membrane

9940:USP39
gene id: 9940:USP39
uniprot id: A0A6P3YID2
names: Subcellular Location Annotation
messages: Nucleus

9940:OTX2
gene id: 9940:OTX2
uniprot id: A0A6P7EXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9940:ECE1
gene id: 9940:ECE1
uniprot id: W5PFK6
names: Function
messages: Converts big endothelin-1 to endothelin-1.

9940:NUDT18
gene id: 9940:NUDT18
uniprot id: A0A6P3E0Q9
names: Caution
names: Similarity
messages: Belongs to the Nudix hydrolase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIGK
gene id: 9940:PIGK
uniprot id: W5PTI2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Endoplasmic reticulum membrane
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

9940:CNOT2
gene id: 9940:CNOT2
uniprot id: A0A6P3TLJ2
uniprot id: W5QG54
names: Caution
names: Similarity
messages: Belongs to the CNOT2/3/5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFAF1
gene id: 9940:NDUFAF1
uniprot id: W5QGK9
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

9940:B3GNT2
gene id: 9940:B3GNT2
uniprot id: A0A6P3E762
uniprot id: W5QE49
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF655
gene id: 9940:ZNF655
uniprot id: A0A6P3ERT2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP298
gene id: 9940:CFAP298
uniprot id: W5PVP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9940:SCGB1C1
gene id: 9940:SCGB1C1
uniprot id: W5PHG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

9940:SIX1
gene id: 9940:SIX1
uniprot id: A0A6P9FRF6
uniprot id: D3U1G0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRYBB2
gene id: 9940:CRYBB2
uniprot id: A0A6P3YR18
uniprot id: W5QCG5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GCSAM
gene id: 9940:GCSAM
uniprot id: A0A6P3E7U2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HAUS1
gene id: 9940:HAUS1
uniprot id: W5NYC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

9940:TAS2R1
gene id: 9940:TAS2R1
uniprot id: A0A835ZRP1
uniprot id: W5P6X6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF13
gene id: 9940:RNF13
uniprot id: A0A6P3E0F8
uniprot id: A0A6P3TEX6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119832
gene id: 9940:LOC101119832
uniprot id: A0A6P3EGX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAF12
gene id: 9940:TAF12
uniprot id: A0A6P3T9R0
uniprot id: A0A6P3TI94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP5MC1
gene id: 9940:ATP5MC1
uniprot id: A0A836A709
uniprot id: P17605
names: Caution
names: Disease Annotation
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase C chain family.
messages: Homooligomer (By similarity). F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with TMEM70 (homooligomer form); this interaction facilitates the oligomer formation of subunit c/ATP5MC1 (c-ring) and the c-ring membrane insertion and also protects ATP5MC1 against intramitochondrial proteolysis (By similarity).
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: There are three genes which encode the ATP synthase proteolipid and they specify precursors with different import sequences but identical mature proteins.
messages: This protein is the major protein stored in the storage bodies of animals or humans affected with ceroid lipofuscinosis (Batten disease).
messages: Trimethylated by ATPSCKMT at Lys-104. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration.

9940:CD81
gene id: 9940:CD81
uniprot id: B2MVW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:UMPS
gene id: 9940:UMPS
uniprot id: A0A836D7G9
names: Caution
names: Similarity
messages: In the C-terminal section; belongs to the OMP decarboxylase family.
messages: In the N-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105010
gene id: 9940:LOC101105010
uniprot id: A0A6P3EA30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHBDD1
gene id: 9940:RHBDD1
uniprot id: A0A6P3EA60
uniprot id: A0A6P3TI30
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HHIPL2
gene id: 9940:HHIPL2
uniprot id: W5PV41
names: Similarity
messages: Belongs to the HHIP family.

9940:PROM2
gene id: 9940:PROM2
uniprot id: W5PXF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

9940:LOC101118606
gene id: 9940:LOC101118606
uniprot id: A0A6P3TD01
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMLHE
gene id: 9940:TMLHE
uniprot id: W5P0Q7
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

9940:PITX3
gene id: 9940:PITX3
uniprot id: D3GN34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9940:HPSE
gene id: 9940:HPSE
uniprot id: W5NWF9
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9940:SLC30A7
gene id: 9940:SLC30A7
uniprot id: C7BDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

9940:UBTD1
gene id: 9940:UBTD1
uniprot id: A0A6P3YNU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118053
gene id: 9940:LOC101118053
uniprot id: W5P441
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9940:LOC443348
gene id: 9940:LOC443348
uniprot id: Q28546
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:LOC101119721
gene id: 9940:LOC101119721
uniprot id: A0A8N7XJB5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSG101
gene id: 9940:TSG101
uniprot id: A0A6P3ED58
uniprot id: W5PID5
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITGA2B
gene id: 9940:ITGA2B
uniprot id: W5PEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:EIF2S1
gene id: 9940:EIF2S1
uniprot id: A0A6P3E6D2
uniprot id: A0A6P3EBC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLK4
gene id: 9940:CLK4
uniprot id: A0A6P3EDW9
uniprot id: W5P9Q7
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL1A
gene id: 9940:IL1A
uniprot id: Q28579
uniprot id: W5QI89
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated within its nuclear localization sequence, which impacts subcellular localization.
messages: Belongs to the IL-1 family.
messages: Cytokine constitutively present intracellularly in nearly all resting non-hematopoietic cells that plays an important role in inflammation and bridges the innate and adaptive immune systems. After binding to its receptor IL1R1 together with its accessory protein IL1RAP, forms the high affinity interleukin-1 receptor complex. Signaling involves the recruitment of adapter molecules such as MYD88, IRAK1 or IRAK4. In turn, mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways. Within the cell, acts as an alarmin and cell death results in its liberation in the extracellular space after disruption of the cell membrane to induce inflammation and alert the host to injury or damage. In addition to its role as a danger signal, which occurs when the cytokine is passively released by cell necrosis, directly senses DNA damage and acts as signal for genotoxic stress without loss of cell integrity.
messages: Cytoplasm
messages: Monomer. Interacts with TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion. Interacts with IL1R1. Interacts with S100A13; this interaction is the first step in the export of IL1A, followed by direct translocation of this complex across the plasma membrane.
messages: Nucleus
messages: Phosphorylated. Phosphorylation greatly enhances susceptibility to digestion and promotes the conversion of pre-IL1A alpha to the biologically active IL1A.
messages: Proteolytic processed by CAPN1 in a calcium-dependent manner. Cleavage from 31 kDa precursor to 18 kDa biologically active molecules.
messages: Secreted
messages: The similarity among the IL-1 precursors suggests that the amino ends of these proteins serve some as yet undefined function.

9940:METTL13
gene id: 9940:METTL13
uniprot id: A0A836A6W2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MESD
gene id: 9940:MESD
uniprot id: W5Q230
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

9940:LOC101108279
gene id: 9940:LOC101108279
uniprot id: A0A6P3E7L9
uniprot id: W5NTY7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POP4
gene id: 9940:POP4
uniprot id: A0A6P3EJK9
uniprot id: W5P1L8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:ATP2B1
gene id: 9940:ATP2B1
uniprot id: W5Q289
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: synaptic vesicle membrane

9940:ECHDC1
gene id: 9940:ECHDC1
uniprot id: A0A6P3TPR1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9940:LOC780442
gene id: 9940:LOC780442
uniprot id: Q5G2C6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9940:SLC12A1
gene id: 9940:SLC12A1
uniprot id: W5QIP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

9940:RPL7
gene id: 9940:RPL7
uniprot id: A0A6P7DK24
uniprot id: A0A836A4W4
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CUTC
gene id: 9940:CUTC
uniprot id: A0A6P3EQ10
uniprot id: W5PTA5
names: Caution
names: Similarity
messages: Belongs to the CutC family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTCRA
gene id: 9940:PTCRA
uniprot id: A0A6P3EJ44
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119648
gene id: 9940:LOC101119648
uniprot id: W5Q6C0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9940:LPIN2
gene id: 9940:LPIN2
uniprot id: A0A835ZR38
uniprot id: W5PK41
names: Caution
names: Similarity
messages: Belongs to the lipin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110189
gene id: 9940:LOC101110189
uniprot id: A0A6P3EJW9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105400
gene id: 9940:LOC101105400
uniprot id: A0A836ADA3
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LGALS3
gene id: 9940:LGALS3
uniprot id: W5QIW1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9940:P2RY13
gene id: 9940:P2RY13
uniprot id: A0A6P3TCK8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPP21
gene id: 9940:RPP21
uniprot id: A0A6P3EJF2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CREM
gene id: 9940:CREM
uniprot id: A7KP99
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101109479
gene id: 9940:LOC101109479
uniprot id: W5Q6S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TIMM21
gene id: 9940:TIMM21
uniprot id: A0A6P3EDT2
uniprot id: W5P3Q1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane
messages: Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex. Probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TCHHL1
gene id: 9940:TCHHL1
uniprot id: A0A836AP85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP9X
gene id: 9940:USP9X
uniprot id: A0A6P3TFG6
uniprot id: W5NVJ3
names: Caution
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC123
gene id: 9940:CDC123
uniprot id: W5Q111
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

9940:C12H1orf115
gene id: 9940:C12H1orf115
uniprot id: A0A6P3EHX4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARF6
gene id: 9940:ARF6
uniprot id: C5IWU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

9940:SLC39A1
gene id: 9940:SLC39A1
uniprot id: C7BDW2
names: Subcellular Location Annotation
messages: Membrane

9940:FGD4
gene id: 9940:FGD4
uniprot id: W5QDJ8
names: Subcellular Location Annotation
messages: cytoskeleton

9940:XPNPEP2
gene id: 9940:XPNPEP2
uniprot id: W5Q009
names: Similarity
messages: Belongs to the peptidase M24B family.

9940:RPS18
gene id: 9940:RPS18
uniprot id: A0A6P3ENG9
names: Caution
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PKN2
gene id: 9940:PKN2
uniprot id: A0A6P3TFC1
uniprot id: W5Q018
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EMC7
gene id: 9940:EMC7
uniprot id: A0A6P3EAW9
uniprot id: W5QF74
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:S100A4
gene id: 9940:S100A4
uniprot id: A0A6P3DZN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35F1
gene id: 9940:SLC35F1
uniprot id: A0A6P3E6K9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:REM1
gene id: 9940:REM1
uniprot id: A0A6P3TSZ3
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9940:ABITRAM
gene id: 9940:ABITRAM
uniprot id: A0A6P3E0W8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: growth cone
messages: lamellipodium

9940:MSH3
gene id: 9940:MSH3
uniprot id: W5PZR8
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

9940:SGK2
gene id: 9940:SGK2
uniprot id: A0A6P7ENR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Cytoplasm

9940:EPG5
gene id: 9940:EPG5
uniprot id: W5NX74
names: Similarity
messages: Belongs to the EPG5 family.

9940:SUCLG2
gene id: 9940:SUCLG2
uniprot id: W5PL67
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

9940:PTGFR
gene id: 9940:PTGFR
uniprot id: A0A836AP34
uniprot id: Q28905
names: Caution
names: Developmental Stage
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Expression is high in the midluteal phase corpus luteum and decreases during luteolysis.
messages: Membrane
messages: Receptor for prostaglandin F2-alpha (PGF2-alpha). The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system. Initiates luteolysis in the corpus luteum.
messages: Shows agonist-independent constitutive activity, but is still responsive to agonist.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112590
gene id: 9940:LOC101112590
uniprot id: A0A088Q711
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:CYRIA
gene id: 9940:CYRIA
uniprot id: A0A6P3TKH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9940:ALDH7A1
gene id: 9940:ALDH7A1
uniprot id: W5QAE8
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

9940:DCT
gene id: 9940:DCT
uniprot id: B3VKX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9940:SPR
gene id: 9940:SPR
uniprot id: A0A836A7E0
uniprot id: W5PPU0
names: Caution
names: Similarity
messages: Belongs to the sepiapterin reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108705
gene id: 9940:LOC101108705
uniprot id: A0A836APA1
names: Caution
names: Similarity
messages: Belongs to the GST superfamily. Mu family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TIGD4
gene id: 9940:TIGD4
uniprot id: W5Q0B7
names: Subcellular Location Annotation
messages: Nucleus

9940:FBXL21P
gene id: 9940:FBXL21P
uniprot id: B3FL73
names: Function
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Expressed in the adenohypophysis, hypothalamus (especially in the suprachiasmatic nucleus or nuclei, SCN) and pineal, all neuroendocrine structures associated with timing and homeostasis.
messages: Nucleus
messages: Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXL21) composed of CUL1, SKP1, RBX1 and FBXL21. Interacts with CRY2 (By similarity). Interacts with CRY1.
messages: Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities.
messages: cytosol

9940:PIAS2
gene id: 9940:PIAS2
uniprot id: A0A6P3YTC9
names: Caution
names: Similarity
messages: Belongs to the PIAS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLAAT3
gene id: 9940:PLAAT3
uniprot id: A0A6P3EDB4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADGRD1
gene id: 9940:ADGRD1
uniprot id: W5PZY4
uniprot id: W5PZY6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:CCDC107
gene id: 9940:CCDC107
uniprot id: A0A6P3E0T9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM124B
gene id: 9940:FAM124B
uniprot id: W5QGS7
names: Similarity
messages: Belongs to the FAM124 family.

9940:HERPUD1
gene id: 9940:HERPUD1
uniprot id: A0A6P3EJF3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NSL1
gene id: 9940:NSL1
uniprot id: A0A6P3EJX7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RGN
gene id: 9940:RGN
uniprot id: B3VSC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

9940:NELFCD
gene id: 9940:NELFCD
uniprot id: A0A6P3YM18
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRIPT
gene id: 9940:CRIPT
uniprot id: A0A6P3EB18
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AMPD3
gene id: 9940:AMPD3
uniprot id: W5PNN0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

9940:LOC101103602
gene id: 9940:LOC101103602
uniprot id: W5NWU7
names: Similarity
messages: Belongs to the amidase family.

9940:SLC45A2
gene id: 9940:SLC45A2
uniprot id: W5PQN6
names: Subcellular Location Annotation
messages: Membrane

9940:GSS
gene id: 9940:GSS
uniprot id: W5PMH1
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

9940:ZMAT3
gene id: 9940:ZMAT3
uniprot id: A0A6P3T2I1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRY1
gene id: 9940:CRY1
uniprot id: A0A6P3TA66
uniprot id: A0A836D841
uniprot id: W5Q8S7
names: Caution
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VAMP7
gene id: 9940:VAMP7
uniprot id: A0A6P9FRF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9940:ODF3L1
gene id: 9940:ODF3L1
uniprot id: A0A6P3EE92
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CASP9
gene id: 9940:CASP9
uniprot id: A0A836CYM2
uniprot id: W5PIY5
names: Caution
names: Similarity
messages: Belongs to the peptidase C14A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBC1D23
gene id: 9940:TBC1D23
uniprot id: W5Q9B7
uniprot id: W5Q9B8
names: Subcellular Location Annotation
messages: trans-Golgi network

9940:PEX3
gene id: 9940:PEX3
uniprot id: A0A6P3EBZ6
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with PEX19.
messages: Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.
messages: Peroxisome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC114108702
gene id: 9940:LOC114108702
uniprot id: A0A6P7DS10
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

9940:TAF5
gene id: 9940:TAF5
uniprot id: W5NZT1
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

9940:ANKRD13A
gene id: 9940:ANKRD13A
uniprot id: A0A6P3EBK7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9940:ZACN
gene id: 9940:ZACN
uniprot id: W5PE38
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:GLRA3
gene id: 9940:GLRA3
uniprot id: A0A6P3E9G5
uniprot id: W5Q126
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MIEN1
gene id: 9940:MIEN1
uniprot id: A0A6P3EHE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A15
gene id: 9940:SLC25A15
uniprot id: A0A6P3YJJ7
uniprot id: B2MVX3
uniprot id: W5PIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:WSCD2
gene id: 9940:WSCD2
uniprot id: A0A6P3EMF5
uniprot id: A0A6P3T237
names: Caution
names: Similarity
messages: Belongs to the WSCD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC443322
gene id: 9940:LOC443322
uniprot id: R9QYM6
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9940:DRD2
gene id: 9940:DRD2
uniprot id: A0A6P3EG64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD13
gene id: 9940:PSMD13
uniprot id: A0A6P3EKA2
uniprot id: W5PFU1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EDNRB
gene id: 9940:EDNRB
uniprot id: A0A1X9T5Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:TMIE
gene id: 9940:TMIE
uniprot id: A0A836A034
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHF5A
gene id: 9940:PHF5A
uniprot id: A0A6P3E3L9
names: Caution
names: Similarity
messages: Belongs to the PHF5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BORCS5
gene id: 9940:BORCS5
uniprot id: A0A6P3E3F1
uniprot id: W5QI72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS5 family.
messages: Lysosome membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PKP4
gene id: 9940:PKP4
uniprot id: W5PCM5
names: Similarity
messages: Belongs to the beta-catenin family.

9940:PDCD4
gene id: 9940:PDCD4
uniprot id: A0A6P3EKV3
names: Similarity
messages: Belongs to the PDCD4 family.

9940:LOC101121054
gene id: 9940:LOC101121054
uniprot id: A0A6P3E6X7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101101979
gene id: 9940:LOC101101979
uniprot id: A0A6P3TDD8
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:ATP6V1A
gene id: 9940:ATP6V1A
uniprot id: A0A6P3DZL2
uniprot id: A0A6P7EWC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: clathrin-coated vesicle membrane
messages: secretory vesicle

9940:FGF11
gene id: 9940:FGF11
uniprot id: A0A6P3ED48
uniprot id: W5PV88
names: Caution
names: Similarity
messages: Belongs to the heparin-binding growth factors family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TASOR2
gene id: 9940:TASOR2
uniprot id: W5PEW1
names: Similarity
messages: Belongs to the TASOR family.

9940:PDXK
gene id: 9940:PDXK
uniprot id: P82197
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Activated by K(+) (Probable). Activity is increased in the presence of Na(+) (By similarity).
messages: Belongs to the pyridoxine kinase family.
messages: Catalyzes the phosphorylation of the dietary vitamin B6 vitamers pyridoxal (PL), pyridoxine (PN) and pyridoxamine (PM) to form pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), respectively (PubMed:14722069) (By similarity). PLP is the active form of vitamin B6, and acts as a cofactor for over 140 different enzymatic reactions (By similarity).
messages: Homodimer.
messages: Ubiquitous.
messages: cytosol

9940:CHRNB3
gene id: 9940:CHRNB3
uniprot id: A0A6P3TKF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:MNS1
gene id: 9940:MNS1
uniprot id: A0A836AC46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium axoneme
messages: flagellum axoneme

9940:ZER1
gene id: 9940:ZER1
uniprot id: A0A6P3YKE1
names: Caution
names: Similarity
messages: Belongs to the zyg-11 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERGIC2
gene id: 9940:ERGIC2
uniprot id: A0A6P3EC65
uniprot id: A0A6P3TQH6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCAR1
gene id: 9940:CCAR1
uniprot id: A0A6P3YT98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAF1
gene id: 9940:TAF1
uniprot id: A0A6P3TFS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103853
gene id: 9940:LOC101103853
uniprot id: W5Q1C0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:KAT7
gene id: 9940:KAT7
uniprot id: W5P6L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9940:TRMT6
gene id: 9940:TRMT6
uniprot id: A0A6P3EIQ4
uniprot id: W5Q9C2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCHCR1
gene id: 9940:CCHCR1
uniprot id: W5PKV4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a regulator of keratinocyte proliferation or differentiation.
messages: Nucleus

9940:ABCG4
gene id: 9940:ABCG4
uniprot id: A0A835ZZ28
uniprot id: W5PWX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPT1
gene id: 9940:TPT1
uniprot id: A0A6P9FQR6
names: Similarity
messages: Belongs to the TCTP family.

9940:PREB
gene id: 9940:PREB
uniprot id: A0A6P3E726
uniprot id: W5QCW4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

9940:RUVBL2
gene id: 9940:RUVBL2
uniprot id: A0A6P3EJV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPA1A
gene id: 9940:HSPA1A
uniprot id: H2DGR2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9940:AVPR1A
gene id: 9940:AVPR1A
uniprot id: E3V2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl-inositol-calcium second messenger system.

9940:LOC101115423
gene id: 9940:LOC101115423
uniprot id: W5PAF1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PEX14
gene id: 9940:PEX14
uniprot id: A0A6P3E8P8
uniprot id: W5P4D3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPP2
gene id: 9940:SPP2
uniprot id: A0A836APB1
uniprot id: Q70TH4
uniprot id: W5QCY7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Multiply phosphorylated at serine residues.
messages: Phosphorylation sites are present in the extracellular medium.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SORD
gene id: 9940:SORD
uniprot id: A0A6P3E7V9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Mitochondrion membrane
messages: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: flagellum

9940:LOC101103474
gene id: 9940:LOC101103474
uniprot id: W5Q3S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101115226
gene id: 9940:LOC101115226
uniprot id: W5NT84
names: Similarity
messages: Belongs to the NXPE family.

9940:TAF7
gene id: 9940:TAF7
uniprot id: A0A6P3EE47
uniprot id: W5PXG1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAM1L1
gene id: 9940:TRAM1L1
uniprot id: A0A6P3EDJ5
uniprot id: W5NQ10
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THADA
gene id: 9940:THADA
uniprot id: W5PAY3
names: Similarity
messages: Belongs to the THADA family.

9940:COQ5
gene id: 9940:COQ5
uniprot id: A0A6P3ENQ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTMA
gene id: 9940:PTMA
uniprot id: A0A6P3TJX9
uniprot id: A0A6P3YK54
names: Caution
names: Similarity
messages: Belongs to the pro/parathymosin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC25C
gene id: 9940:CDC25C
uniprot id: W5Q3S7
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9940:AKIRIN1
gene id: 9940:AKIRIN1
uniprot id: B2ZEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

9940:LOC101121883
gene id: 9940:LOC101121883
uniprot id: A0A6P3T572
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF852
gene id: 9940:ZNF852
uniprot id: A0A6P3YNV4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNRPC
gene id: 9940:SNRPC
uniprot id: W5PMC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9940:APOC2
gene id: 9940:APOC2
uniprot id: A0A6P7ET07
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C2 family.
messages: Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CR2
gene id: 9940:CR2
uniprot id: O46545
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:UBB
gene id: 9940:UBB
uniprot id: P0CG55
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin family.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
messages: For the sake of clarity sequence features are annotated only for the first chain, and are not repeated for each of the following chains.
messages: Interacts with SKP1-KMD2A and SKP1-KMD2B complexes.
messages: Mitochondrion outer membrane
messages: Mono-ADP-ribosylated at the C-terminus by PARP9, a component of the PPAR9-DTX3L complex. ADP-ribosylation requires processing by E1 and E2 enzymes and prevents ubiquitin conjugation to substrates such as histones.
messages: Nucleus
messages: Phosphorylated at Ser-65 by PINK1 during mitophagy. Phosphorylated ubiquitin specifically binds and activates parkin (PRKN), triggering mitophagy. Phosphorylation does not affect E1-mediated E2 charging of ubiquitin but affects discharging of E2 enzymes to form polyubiquitin chains. It also affects deubiquitination by deubiquitinase enzymes such as USP30.
messages: Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.

9940:LOC101102990
gene id: 9940:LOC101102990
uniprot id: A0A6P3TH10
uniprot id: A0A6P7DS65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIF2B
gene id: 9940:KIF2B
uniprot id: W5PVV1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:MAPRE2
gene id: 9940:MAPRE2
uniprot id: A0A6P3EFZ9
uniprot id: W5P6Z6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:PRND
gene id: 9940:PRND
uniprot id: A0A835ZVR1
uniprot id: A7U7P0
uniprot id: Q9GJY2
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: A short helical region is required and sufficient for Cu(2+) binding.
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane
messages: N-glycosylated.
messages: O-glycosylated.
messages: Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (By similarity).
messages: Strongly expressed in testis. Detected at low levels in lymph node, spleen and ovary.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RORB
gene id: 9940:RORB
uniprot id: A0A6P3CX41
uniprot id: B3F205
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AURKA
gene id: 9940:AURKA
uniprot id: B7U174
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

9940:LOC101108778
gene id: 9940:LOC101108778
uniprot id: A0A8N7XJ60
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110617
gene id: 9940:LOC101110617
uniprot id: W5PCD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CDX1
gene id: 9940:CDX1
uniprot id: W5P9Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9940:CLTB
gene id: 9940:CLTB
uniprot id: A0A6P3E5R3
uniprot id: W5NVY3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: coated pit

9940:DERL2
gene id: 9940:DERL2
uniprot id: A0A6P3EH25
uniprot id: W5NYS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAD51
gene id: 9940:RAD51
uniprot id: A0A6P7EB86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

9940:MRPL19
gene id: 9940:MRPL19
uniprot id: A0A6P3E789
uniprot id: W5NSA9
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FUT1
gene id: 9940:FUT1
uniprot id: A0A6P3EK11
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FABP7
gene id: 9940:FABP7
uniprot id: A0A6P3EFP0
uniprot id: A0A6P7DE44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113108
gene id: 9940:LOC101113108
uniprot id: A0A835ZVL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BTG2
gene id: 9940:BTG2
uniprot id: A0A6P9FQT1
uniprot id: F4MJ45
names: Caution
names: Similarity
messages: Belongs to the BTG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KDR
gene id: 9940:KDR
uniprot id: W5NSG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9940:CLDN18
gene id: 9940:CLDN18
uniprot id: W5PCV1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9940:GJA5
gene id: 9940:GJA5
uniprot id: W5PRE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9940:LOC101106492
gene id: 9940:LOC101106492
uniprot id: A0A836D957
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: invadopodium membrane
messages: lamellipodium membrane

9940:FAM118B
gene id: 9940:FAM118B
uniprot id: A0A6P7DA77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

9940:BNIPL
gene id: 9940:BNIPL
uniprot id: A0A6P3E4E2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIFC1
gene id: 9940:KIFC1
uniprot id: A0A835ZSA0
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FMO1
gene id: 9940:FMO1
uniprot id: A0A6P3EB41
uniprot id: W5PSR9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADAM10
gene id: 9940:ADAM10
uniprot id: W5QI59
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: adherens junction

9940:LEO1
gene id: 9940:LEO1
uniprot id: A0A6P3E694
uniprot id: W5QIH1
names: Caution
names: Similarity
messages: Belongs to the LEO1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106201
gene id: 9940:LOC101106201
uniprot id: A0A6P3EL57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDE1
gene id: 9940:GDE1
uniprot id: A0A6P3EQR0
uniprot id: W5PQZ5
names: Caution
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119090
gene id: 9940:LOC101119090
uniprot id: A0A836D7W6
uniprot id: W5PMU0
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:P2RY6
gene id: 9940:P2RY6
uniprot id: A0A6P3YLV3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105610402
gene id: 9940:LOC105610402
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TM9SF1
gene id: 9940:TM9SF1
uniprot id: A0A836A557
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C24H7orf61
gene id: 9940:C24H7orf61
uniprot id: A0A6P3EEA7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHML
gene id: 9940:CHML
uniprot id: A0A6P3TLQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

9940:C1D
gene id: 9940:C1D
uniprot id: A0A6P3E9V5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:FBLN7
gene id: 9940:FBLN7
uniprot id: W5PYI0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:STAG1
gene id: 9940:STAG1
uniprot id: A0A6P3TFQ1
uniprot id: W5PDD5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centromere

9940:PSMB5
gene id: 9940:PSMB5
uniprot id: A0A6P3EAT1
uniprot id: W5QDM2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB5 displays a chymotrypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADRB3
gene id: 9940:ADRB3
uniprot id: Q2XQ07
uniprot id: Q9XT58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB3 sub-subfamily.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

9940:SCUBE3
gene id: 9940:SCUBE3
uniprot id: W5PP71
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:SLC66A2
gene id: 9940:SLC66A2
uniprot id: A0A6P7DCQ5
names: Subcellular Location Annotation
messages: Membrane

9940:ZBP1
gene id: 9940:ZBP1
uniprot id: A0A6P3EF73
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KATNAL1
gene id: 9940:KATNAL1
uniprot id: A0A6P3TQW1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

9940:ARRDC3
gene id: 9940:ARRDC3
uniprot id: A0A6P3E690
names: Caution
names: Similarity
messages: Belongs to the arrestin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL22L1
gene id: 9940:RPL22L1
uniprot id: A0A6P7EL92
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOMEZ
gene id: 9940:HOMEZ
uniprot id: W5QDI1
names: Subcellular Location Annotation
messages: Nucleus

9940:STAM2
gene id: 9940:STAM2
uniprot id: A0A6P3E8P9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GFUS
gene id: 9940:GFUS
uniprot id: A0A836CZ08
uniprot id: W5Q563
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHOA
gene id: 9940:RHOA
uniprot id: A0A6P9FQL7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IMMT
gene id: 9940:IMMT
uniprot id: W5QHI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

9940:GJC1
gene id: 9940:GJC1
uniprot id: A0A6P7EG46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9940:RCL1
gene id: 9940:RCL1
uniprot id: A0A6P3E899
uniprot id: W5PVF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:RANGRF
gene id: 9940:RANGRF
uniprot id: A0A6P3EA34
uniprot id: W5NQU3
names: Caution
names: Similarity
messages: Belongs to the MOG1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNAP23
gene id: 9940:SNAP23
uniprot id: A0A6P3EEY0
uniprot id: W5QH64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: synaptosome

9940:CD14
gene id: 9940:CD14
uniprot id: Q06AV9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Interacts with LPAR1.
messages: Cell membrane
messages: Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-).
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft
messages: Secreted

9940:B3GALT1
gene id: 9940:B3GALT1
uniprot id: A0A6P3YK02
uniprot id: W5QEG7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BGLAP
gene id: 9940:BGLAP
uniprot id: Q1ZZ82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

9940:POLR1H
gene id: 9940:POLR1H
uniprot id: A0A6P3EF08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase I (Pol I) complex consisting of at least 13 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase I which synthesizes ribosomal RNA precursors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:UPRT
gene id: 9940:UPRT
uniprot id: A0A6P3EN25
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF113A
gene id: 9940:RNF113A
uniprot id: A0A835ZJY2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC24A5
gene id: 9940:SLC24A5
uniprot id: G3FHC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9940:TRMT12
gene id: 9940:TRMT12
uniprot id: A0A835ZYL6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYOZ1
gene id: 9940:MYOZ1
uniprot id: W5PDD8
names: Similarity
messages: Belongs to the myozenin family.

9940:VPS45
gene id: 9940:VPS45
uniprot id: A0A6P3E720
names: Caution
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLHL7
gene id: 9940:KLHL7
uniprot id: A0A6P3E4K3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SHMT2
gene id: 9940:SHMT2
uniprot id: A0A6P3TJZ7
names: Caution
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDIAS
gene id: 9940:DDIAS
uniprot id: A0A835ZWV3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABRB2
gene id: 9940:GABRB2
uniprot id: I2BJM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:ADAL
gene id: 9940:ADAL
uniprot id: A0A6P3EEB8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UTP11
gene id: 9940:UTP11
uniprot id: A0A6P3T804
uniprot id: W5QFC5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:CHCHD3
gene id: 9940:CHCHD3
uniprot id: A0A6P3CWZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115495
gene id: 9940:LOC101115495
uniprot id: W5PD71
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:SMCO3
gene id: 9940:SMCO3
uniprot id: A0A6P3E3E6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTRT2
gene id: 9940:ACTRT2
uniprot id: A0A6P3EI47
uniprot id: W5P561
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR2B
gene id: 9940:POLR2B
uniprot id: A0A6P3E6X2
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TACSTD2
gene id: 9940:TACSTD2
uniprot id: A0A6P3ET79
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112889
gene id: 9940:LOC101112889
uniprot id: A0A6P3YU72
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDC
gene id: 9940:PDC
uniprot id: W5PC40
names: Similarity
messages: Belongs to the phosducin family.

9940:LOC101102809
gene id: 9940:LOC101102809
uniprot id: A0A6P3E5S2
uniprot id: W5P7D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RASL11B
gene id: 9940:RASL11B
uniprot id: A0A6P3EF44
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CXCL1
gene id: 9940:CXCL1
uniprot id: O46678
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Has chemotactic activity for neutrophils.
messages: Secreted

9940:SNX5
gene id: 9940:SNX5
uniprot id: A0A6P3TJB7
uniprot id: A0A6P7EW54
names: Caution
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DRAM2
gene id: 9940:DRAM2
uniprot id: A0A6P3E5H8
names: Subcellular Location Annotation
messages: Membrane

9940:PRPS1
gene id: 9940:PRPS1
uniprot id: A0A6P3TG37
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB21
gene id: 9940:RAB21
uniprot id: C5IJ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

9940:NEUROD1
gene id: 9940:NEUROD1
uniprot id: A0A6P3TCD6
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE2B
gene id: 9940:UBE2B
uniprot id: W5PWV6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:SELENOI
gene id: 9940:SELENOI
uniprot id: W5QBR4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9940:DHRS7
gene id: 9940:DHRS7
uniprot id: A0A6P3EB99
uniprot id: W5QJ03
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SENP2
gene id: 9940:SENP2
uniprot id: A0A6P3TGE4
uniprot id: W5QH92
names: Caution
names: Similarity
messages: Belongs to the peptidase C48 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MARVELD2
gene id: 9940:MARVELD2
uniprot id: W5P6E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9940:LOC101104297
gene id: 9940:LOC101104297
uniprot id: W5QED4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

9940:TMEM98
gene id: 9940:TMEM98
uniprot id: A0A6P3YJZ5
uniprot id: W5PJS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM98 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular exosome

9940:G6PC1
gene id: 9940:G6PC1
uniprot id: W5P1N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9940:DSC2
gene id: 9940:DSC2
uniprot id: W5PA25
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9940:MTOR
gene id: 9940:MTOR
uniprot id: B9VXW5
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

9940:MANF
gene id: 9940:MANF
uniprot id: A0A6P3EIS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEPHS2
gene id: 9940:SEPHS2
uniprot id: A0A835ZMN2
names: Caution
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRDX5
gene id: 9940:PRDX5
uniprot id: W5PAL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

9940:DCAF16
gene id: 9940:DCAF16
uniprot id: A0A6P3TEM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OVGP1
gene id: 9940:OVGP1
uniprot id: Q28542
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the glycosyl hydrolase 18 family.
messages: Binds to oocyte zona pellucida in vivo. May play a role in the fertilization process and/or early embryonic development.
messages: Levels are highest in the fimbria and ampulla at estrus and on day 1 of pregnancy, when gamete transport and fertilization occurs in the E2-dominated fallopian tube. Levels decline significantly on day 2 and undergo a further significant reduction on day 3 of pregnancy coincident with transport of the embryo from the oviduct to the uterus, a reproductive stage associated with rising progesterone levels.
messages: Oviduct.
messages: secretory vesicle

9940:INSIG1
gene id: 9940:INSIG1
uniprot id: W5P9G9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9940:ATXN1L
gene id: 9940:ATXN1L
uniprot id: A0A6P3EC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

9940:MPV17L
gene id: 9940:MPV17L
uniprot id: A0A6P3EGA2
uniprot id: A0A6P7DFF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OXCT1
gene id: 9940:OXCT1
uniprot id: A0A6P3ELR7
uniprot id: W5PGM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL6IP5
gene id: 9940:ARL6IP5
uniprot id: A0A6P3EEI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SSTR2
gene id: 9940:SSTR2
uniprot id: A0A6P3EAM9
uniprot id: W5NPT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PEX13
gene id: 9940:PEX13
uniprot id: A0A6P3E2L7
uniprot id: W5NT51
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CORO2A
gene id: 9940:CORO2A
uniprot id: W5PN93
names: Similarity
messages: Belongs to the WD repeat coronin family.

9940:LOC101112761
gene id: 9940:LOC101112761
uniprot id: A0A835ZUG2
uniprot id: W5PTD8
names: Caution
names: Similarity
messages: Belongs to the MS4A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM138
gene id: 9940:TMEM138
uniprot id: W5PTH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

9940:GNAI1
gene id: 9940:GNAI1
uniprot id: A0A6P3YHI7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BMP7
gene id: 9940:BMP7
uniprot id: W8E0V8
names: Similarity
messages: Belongs to the TGF-beta family.

9940:UCHL5
gene id: 9940:UCHL5
uniprot id: W5PIL6
names: Similarity
messages: Belongs to the peptidase C12 family.

9940:JUN
gene id: 9940:JUN
uniprot id: W5PJV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

9940:SLC7A2
gene id: 9940:SLC7A2
uniprot id: W5PHN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9940:TMC7
gene id: 9940:TMC7
uniprot id: W5PPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9940:PDE4C
gene id: 9940:PDE4C
uniprot id: W5PTV4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9940:TP53I11
gene id: 9940:TP53I11
uniprot id: A0A6P3EAL6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RDX
gene id: 9940:RDX
uniprot id: W5PUV9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9940:TIMM10
gene id: 9940:TIMM10
uniprot id: A0A6P3T5K1
uniprot id: A0A6P3TFS9
names: Caution
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS26
gene id: 9940:RPS26
uniprot id: Q6Q312
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS26 family.
messages: Component of the 40S small ribosomal subunit.
messages: Cytoplasm
messages: Rough endoplasmic reticulum
messages: cytosol

9940:LOC101102419
gene id: 9940:LOC101102419
uniprot id: W5PB32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:NCAPH
gene id: 9940:NCAPH
uniprot id: A0A6P3YGT1
uniprot id: W5PWU1
uniprot id: W5PWV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Belongs to the ITPRIP family.
messages: Chromosome
messages: Cytoplasm
messages: Membrane
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

9940:ALOX12
gene id: 9940:ALOX12
uniprot id: W5PHM1
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:TAS2R3
gene id: 9940:TAS2R3
uniprot id: A0A6P3TD64
uniprot id: W5NSX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VGLL1
gene id: 9940:VGLL1
uniprot id: W5PN86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9940:LECT2
gene id: 9940:LECT2
uniprot id: A0A6P3E4S0
names: Caution
names: Similarity
messages: Belongs to the LECT2/MIM-1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105957
gene id: 9940:LOC101105957
uniprot id: W5Q1X0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:NCK1
gene id: 9940:NCK1
uniprot id: A0A6P3T7V1
uniprot id: A0A6P3TI97
uniprot id: C8BKC6
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NANOS2
gene id: 9940:NANOS2
uniprot id: W5PPB5
names: Similarity
messages: Belongs to the nanos family.

9940:GABRA2
gene id: 9940:GABRA2
uniprot id: W5Q1N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA2 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendrite

9940:LOC101116273
gene id: 9940:LOC101116273
uniprot id: A0A6P3TDI6
uniprot id: W5PC25
names: Caution
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFTPB
gene id: 9940:SFTPB
uniprot id: A0A6P3TP46
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KNCN
gene id: 9940:KNCN
uniprot id: A0A6P3DYQ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATG4C
gene id: 9940:ATG4C
uniprot id: A0A6P3E6E4
uniprot id: A0A836D6I5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARMH3
gene id: 9940:ARMH3
uniprot id: A0A6P3EQ30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TEX43
gene id: 9940:TEX43
uniprot id: A0A6P3E9E8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRC17
gene id: 9940:LRRC17
uniprot id: A0A6P3E407
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GNPDA2
gene id: 9940:GNPDA2
uniprot id: W5Q0A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9940:EHF
gene id: 9940:EHF
uniprot id: W5QBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9940:HSDL2
gene id: 9940:HSDL2
uniprot id: W5P972
names: Subcellular Location Annotation
messages: Peroxisome

9940:PR
gene id: 9940:PR
uniprot id: O46561
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Expressed in all tissues examined; liver, pituitary, adrenal gland, ovary and fetal liver.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

9940:LOC101114959
gene id: 9940:LOC101114959
uniprot id: W5PTZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:ASPA
gene id: 9940:ASPA
uniprot id: W5Q5Q7
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

9940:LIPC
gene id: 9940:LIPC
uniprot id: A0A6P3E7R6
uniprot id: A0A6P3TQV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SERINC5
gene id: 9940:SERINC5
uniprot id: A0A6P3TQB2
uniprot id: W5Q7V8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116443
gene id: 9940:LOC101116443
uniprot id: A0A6P3E566
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBA52
gene id: 9940:UBA52
uniprot id: A0A836D2E6
uniprot id: P0C276
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: Exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys-11-linked is involved in ERAD (endoplasmic reticulum-associated degradation) and in cell-cycle regulation; Lys-29-linked is involved in proteotoxic stress response and cell cycle; Lys-33-linked is involved in kinase modification; Lys-48-linked is involved in protein degradation via the proteasome; Lys-63-linked is involved in endocytosis, DNA-damage responses as well as in signaling processes leading to activation of the transcription factor NF-kappa-B. Linear polymer chains formed via attachment by the initiator Met lead to cell signaling. Ubiquitin is usually conjugated to Lys residues of target proteins, however, in rare cases, conjugation to Cys or Ser residues has been observed. When polyubiquitin is free (unanchored-polyubiquitin), it also has distinct roles, such as in activation of protein kinases, and in signaling.
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Mono-ADP-ribosylated at the C-terminus by PARP9, a component of the PPAR9-DTX3L complex. ADP-ribosylation requires processing by E1 and E2 enzymes and prevents ubiquitin conjugation to substrates such as histones.
messages: Nucleus
messages: Phosphorylated at Ser-65 by PINK1 during mitophagy. Phosphorylated ubiquitin specifically binds and activates parkin (PRKN), triggering mitophagy. Phosphorylation does not affect E1-mediated E2 charging of ubiquitin but affects discharging of E2 enzymes to form polyubiquitin chains. It also affects deubiquitination by deubiquitinase enzymes such as USP30.
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitin is encoded by 4 different genes. Uba52 and Rps27a genes code for a single copy of ubiquitin fused to the ribosomal proteins L40 and S27a, respectively. UBB and UBC genes code for a polyubiquitin precursor with exact head to tail repeats, the number of repeats differ between species and strains.

9940:ZNF570
gene id: 9940:ZNF570
uniprot id: A0A6P3E9R5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUPT4H1
gene id: 9940:SUPT4H1
uniprot id: A0A6P7EMC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9940:TRAPPC1
gene id: 9940:TRAPPC1
uniprot id: A0A6P3EH65
uniprot id: W5QAA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network

9940:DMAC2L
gene id: 9940:DMAC2L
uniprot id: W5QHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP synthase subunit s family.
messages: Homotetramer. Associates with ATP synthase.
messages: Involved in regulation of mitochondrial membrane ATP synthase. Necessary for H(+) conduction of ATP synthase. Facilitates energy-driven catalysis of ATP synthesis by blocking a proton leak through an alternative proton exit pathway.
messages: Membrane
messages: Mitochondrion inner membrane

9940:GFM2
gene id: 9940:GFM2
uniprot id: A0A6P3EB08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGFS
gene id: 9940:PGFS
uniprot id: A0A6P3E956
names: Caution
names: Similarity
messages: Belongs to the aldo/keto reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BGN
gene id: 9940:BGN
uniprot id: O46390
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Found in several connective tissues, especially in articular cartilages.
messages: Homodimer. Forms a ternary complex with MFAP2 and ELN (By similarity).
messages: May be involved in collagen fiber assembly.
messages: The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate.
messages: extracellular matrix

9940:INSL6
gene id: 9940:INSL6
uniprot id: A0A6P3E5Z7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: May have a role in sperm development and fertilization.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MSANTD3
gene id: 9940:MSANTD3
uniprot id: A0A6P3YJJ3
names: Similarity
messages: Belongs to the MSANTD3 family.

9940:KIF15
gene id: 9940:KIF15
uniprot id: W5P3X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

9940:MRPS7
gene id: 9940:MRPS7
uniprot id: A0A6P3E8C2
uniprot id: W5PMH5
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF185
gene id: 9940:RNF185
uniprot id: A0A6P3EE49
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITGAX
gene id: 9940:ITGAX
uniprot id: D6BMU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:DDX55
gene id: 9940:DDX55
uniprot id: W5NZJ4
names: Similarity
messages: Belongs to the DEAD box helicase family.

9940:CAVIN2
gene id: 9940:CAVIN2
uniprot id: A0A6P3E1I7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: caveola

9940:IL18R1
gene id: 9940:IL18R1
uniprot id: W5PU94
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9940:RAN
gene id: 9940:RAN
uniprot id: A0A6P9FQL0
uniprot id: C5IJA0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPM4
gene id: 9940:TPM4
uniprot id: W5NRW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9940:NGDN
gene id: 9940:NGDN
uniprot id: A0A6P3E7B3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CBX3
gene id: 9940:CBX3
uniprot id: A0A836AE85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HMGCS2
gene id: 9940:HMGCS2
uniprot id: W5QGT9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9940:SLC30A9
gene id: 9940:SLC30A9
uniprot id: W5PX15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

9940:ZSCAN30
gene id: 9940:ZSCAN30
uniprot id: W5P6Q2
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101107252
gene id: 9940:LOC101107252
uniprot id: A0A835ZK36
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HDAC9
gene id: 9940:HDAC9
uniprot id: F8SRE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus

9940:FGF12
gene id: 9940:FGF12
uniprot id: C5ISA5
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9940:ZDHHC15
gene id: 9940:ZDHHC15
uniprot id: A0A6P3ESJ6
uniprot id: W5QA46
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121371
gene id: 9940:LOC101121371
uniprot id: W5Q6M1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9940:PRDX6
gene id: 9940:PRDX6
uniprot id: A0A6P3CY24
uniprot id: M4T8F1
names: Caution
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9940:TRIP12
gene id: 9940:TRIP12
uniprot id: A0A6P3YG59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPL family. K-HECT subfamily.
messages: E3 ubiquitin-protein ligase involved in ubiquitin fusion degradation (UFD) pathway and regulation of DNA repair. Part of the ubiquitin fusion degradation (UFD) pathway, a process that mediates ubiquitination of protein at their N-terminus, regardless of the presence of lysine residues in target proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleoplasm

9940:LOC101111875
gene id: 9940:LOC101111875
uniprot id: A0A6P3E8L6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RETREG1
gene id: 9940:RETREG1
uniprot id: A0A1Y0BRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

9940:LOC101118444
gene id: 9940:LOC101118444
uniprot id: A0A836AG41
uniprot id: W5NTR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDF15
gene id: 9940:GDF15
uniprot id: W5PSA2
names: Similarity
messages: Belongs to the TGF-beta family.

9940:FRZB
gene id: 9940:FRZB
uniprot id: A0A6P7DPG8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

9940:SPRN
gene id: 9940:SPRN
uniprot id: A6XN32
uniprot id: C6ETC1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the SPRN family.
messages: Cell membrane
messages: Mainly expressed in brain.
messages: N-glycosylated.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP (By similarity).
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

9940:CDK5
gene id: 9940:CDK5
uniprot id: B6E1W2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:PSMA3
gene id: 9940:PSMA3
uniprot id: A0A6P3EG85
uniprot id: W5QIY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AP3S1
gene id: 9940:AP3S1
uniprot id: A0A6P3YJX3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD7
gene id: 9940:PSMD7
uniprot id: A0A6P3EL50
uniprot id: W5P0D5
names: Caution
names: Similarity
messages: Belongs to the peptidase M67A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADGB
gene id: 9940:ADGB
uniprot id: W5NW73
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:AGK
gene id: 9940:AGK
uniprot id: A0A6P7E2Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9940:CFL1
gene id: 9940:CFL1
uniprot id: Q6B7M7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin-binding proteins ADF family.
messages: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (By similarity). Important for normal progress through mitosis and normal cytokinesis (By similarity). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (By similarity). Required for the centralization of the mitotic spindle and symmetric division of zygotes (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (By similarity). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (By similarity). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
messages: Can bind G- and F-actin in a 1:1 ratio of cofilin to actin (By similarity). It is a major component of intranuclear and cytoplasmic actin rods (By similarity). Interacts with the subcortical maternal complex (SCMC) via interaction with TLE6 and NLRP5 (By similarity). Interacts with C9orf72 (By similarity).
messages: Inactivated by phosphorylation on Ser-3. Phosphorylated on Ser-3 in resting cells (By similarity). Dephosphorylated by PDXP/chronophin; this restores its activity in promoting actin filament depolymerization. The phosphorylation of Ser-24 may prevent recognition of the nuclear localization signal (By similarity). Phosphorylated via a ARRB1-RAC1-LIMK1-PAK1 cascade upon active ligand stimulation of atypical chemokine receptor ACKR2 (By similarity).
messages: Nucleus matrix
messages: axon
messages: cytoskeleton
messages: growth cone
messages: lamellipodium
messages: lamellipodium membrane
messages: ruffle membrane

9940:MYF6
gene id: 9940:MYF6
uniprot id: B5LZ29
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101101934
gene id: 9940:LOC101101934
uniprot id: A0A835ZP88
uniprot id: W5Q1E5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DEGS1
gene id: 9940:DEGS1
uniprot id: B6UV64
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

9940:PPIP5K2
gene id: 9940:PPIP5K2
uniprot id: W5QAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9940:ADM
gene id: 9940:ADM
uniprot id: A0A6P7EY83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Belongs to the calcitonin family.
messages: Secreted

9940:SFRP2
gene id: 9940:SFRP2
uniprot id: A0A6P9FQI7
uniprot id: C5IWT3
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STRADB
gene id: 9940:STRADB
uniprot id: A0A6P3E6H2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105290
gene id: 9940:LOC101105290
uniprot id: A0A836CVN3
uniprot id: W5QGB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EEF1AKMT3
gene id: 9940:EEF1AKMT3
uniprot id: A0A6P3EBT1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLHL11
gene id: 9940:KLHL11
uniprot id: A0A836A8J4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116843
gene id: 9940:LOC101116843
uniprot id: A0A6P7DGY8
names: Caution
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYP2A6
gene id: 9940:CYP2A6
uniprot id: W5PB29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:LIN37
gene id: 9940:LIN37
uniprot id: A0A6P3EJM4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114861
gene id: 9940:LOC101114861
uniprot id: W5Q6I2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

9940:ZHX1
gene id: 9940:ZHX1
uniprot id: A0A6P3YJE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

9940:SMARCB1
gene id: 9940:SMARCB1
uniprot id: W5PUS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

9940:PLEK2
gene id: 9940:PLEK2
uniprot id: A0A6P3EGB6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHKA2
gene id: 9940:PHKA2
uniprot id: A0A6P3ERT0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121728
gene id: 9940:LOC101121728
uniprot id: A0A836D7D9
uniprot id: W5P909
names: Caution
names: Similarity
messages: Belongs to the LCE family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119218
gene id: 9940:LOC101119218
uniprot id: W5Q8V6
names: Subcellular Location Annotation
messages: extracellular matrix

9940:LOC101117021
gene id: 9940:LOC101117021
uniprot id: A0A835ZNH3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STXBP5L
gene id: 9940:STXBP5L
uniprot id: W5QFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9940:MDFIC
gene id: 9940:MDFIC
uniprot id: W5NUJ3
names: Similarity
messages: Belongs to the MDFI family.

9940:NDUFV3
gene id: 9940:NDUFV3
uniprot id: A0A6P3E7B5
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

9940:IFT172
gene id: 9940:IFT172
uniprot id: A0A6P3E265
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INHBE
gene id: 9940:INHBE
uniprot id: W5PA02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9940:SAT1
gene id: 9940:SAT1
uniprot id: A0A6P3ERT4
uniprot id: W5Q5Q0
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBXO8
gene id: 9940:FBXO8
uniprot id: A0A6P3E1G2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP5F1A
gene id: 9940:ATP5F1A
uniprot id: A0A8N7XJ64
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MATR3
gene id: 9940:MATR3
uniprot id: A0A6P3TSH3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TFPI2
gene id: 9940:TFPI2
uniprot id: W5NS10
names: Subcellular Location Annotation
messages: Secreted

9940:LRRC4C
gene id: 9940:LRRC4C
uniprot id: A0A6P3EGR9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CALM2
gene id: 9940:CALM2
uniprot id: A0A6P7ECH5
uniprot id: Q6YNX6
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calmodulin family.
messages: Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis. Is a regulator of voltage-dependent L-type calcium channels. Mediates calcium-dependent inactivation of CACNA1C. Positively regulates calcium-activated potassium channel activity of KCNN2. Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding. Acts as a sensor to modulate the endoplasmic reticulum contacts with other organelles mediated by VMP1:ATP2A2.
messages: Interacts with CEP97, CCP110, TTN/titin and SRY. Interacts with MYO5A and RRAD (By similarity). Interacts with USP6; the interaction is calcium dependent (By similarity). Interacts with CDK5RAP2. Interacts with SCN5A. Interacts with RYR1 and RYR2 (By similarity). Interacts with FCHO1. Interacts with MIP in a 1:2 stoichiometry; the interaction with the cytoplasmic domains from two MIP subunits promotes MIP water channel closure. Interacts with ORAI1; this may play a role in the regulation of ORAI1-mediated calcium transport. Interacts with SYT7 (By similarity). Interacts with MYO10 and MYO1C (By similarity). Interacts with SLC9A1 in a calcium-dependent manner (By similarity). Interacts with HINT1; interaction increases in the presence of calcium ions (By similarity). Interacts with HINT3 (By similarity).
messages: Phosphorylation results in a decreased activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein has four functional calcium-binding sites.
messages: Ubiquitination results in a strongly decreased activity.
messages: spindle
messages: spindle pole

9940:MAPKAPK3
gene id: 9940:MAPKAPK3
uniprot id: A0A6P3YRQ3
uniprot id: W5PFH4
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HACE1
gene id: 9940:HACE1
uniprot id: A0A6P3EBS0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SRA1
gene id: 9940:SRA1
uniprot id: A0A6P3EE36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOG
gene id: 9940:NOG
uniprot id: D3U2P7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

9940:DCAF12
gene id: 9940:DCAF12
uniprot id: A0A6P3E8Y6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:G6PD
gene id: 9940:G6PD
uniprot id: A1XI86
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis.

9940:B2M
gene id: 9940:B2M
uniprot id: A4ZVY9
uniprot id: Q6QAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta-2-microglobulin family.
messages: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
messages: Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules (By similarity).
messages: Secreted

9940:CRBN
gene id: 9940:CRBN
uniprot id: A0A6P3EEI3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAAH
gene id: 9940:FAAH
uniprot id: A0A6P3E3X1
uniprot id: W5NWR9
names: Caution
names: Similarity
messages: Belongs to the amidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CTH
gene id: 9940:CTH
uniprot id: A0A6P3E429
uniprot id: W5PQY2
names: Caution
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL21
gene id: 9940:RPL21
uniprot id: A0A6P3YJN3
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARPP19
gene id: 9940:ARPP19
uniprot id: A0A836A5U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CTDSP1
gene id: 9940:CTDSP1
uniprot id: A0A6P3T9G5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CALR3
gene id: 9940:CALR3
uniprot id: A0A836A2S3
uniprot id: W5QCE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL52
gene id: 9940:MRPL52
uniprot id: W5QDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL52 family.
messages: Mitochondrion

9940:CHST12
gene id: 9940:CHST12
uniprot id: A0A6P3YPA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HAND1
gene id: 9940:HAND1
uniprot id: Q28555
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein. Forms homodimers and heterodimers with TCF3 gene products E12 and E47, HAND2 and HEY1, HEY2 and HEYL (hairy-related transcription factors). Interacts with MDFIC (By similarity). Interacts with SOX15; the interaction enhances HAND1-induced differentiation of trophoblast giant cells (By similarity).
messages: Phosphorylation by PLK4 disrupts the interaction with MDFIC and leads to translocation into the nucleoplasm, allowing dimerization and transcription factor activity.
messages: Transcription factor that plays an essential role in both trophoblast giant cell differentiation and in cardiac morphogenesis (By similarity). Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity). Acts as a transcriptional repressor of SOX15 (By similarity). In the adult, could be required for ongoing expression of cardiac-specific genes (By similarity).
messages: nucleolus
messages: nucleoplasm

9940:PNOC
gene id: 9940:PNOC
uniprot id: A0A6P7DNQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Secreted

9940:GPR173
gene id: 9940:GPR173
uniprot id: A0A6P3TAX7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAGI3
gene id: 9940:MAGI3
uniprot id: W5QEY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9940:LOC101119281
gene id: 9940:LOC101119281
uniprot id: A0A6P3EN93
uniprot id: W5PIZ5
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLHL20
gene id: 9940:KLHL20
uniprot id: A0A836A754
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HDAC2
gene id: 9940:HDAC2
uniprot id: A0A6P3EBP1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ENO3
gene id: 9940:ENO3
uniprot id: A0A6P3TWQ3
uniprot id: W5P663
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF280D
gene id: 9940:ZNF280D
uniprot id: A0A6P3YIW9
uniprot id: A0A6P3YIY6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119679
gene id: 9940:LOC101119679
uniprot id: A0A6P3EJI1
uniprot id: A0A836CTR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FGD1
gene id: 9940:FGD1
uniprot id: W5P8R2
names: Subcellular Location Annotation
messages: cytoskeleton

9940:SNF8
gene id: 9940:SNF8
uniprot id: A0A6P3EDC2
uniprot id: W5P9G5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111190
gene id: 9940:LOC101111190
uniprot id: A0A6P3E4Y6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNAP25
gene id: 9940:SNAP25
uniprot id: W5PKN8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A; this complex binds CPLX1. Found in a complex containing SYT1, SV2B and syntaxin-1. Found in a ternary complex with STX1A and VAMP8. Interacts with HSC70 and with SYT9, forming a complex with DNAJC5. The interaction with SYT9 is inhibited in presence of calcium. Isoform 1 and isoform 2 interact with BLOC1S6. Interacts with CENPF. Interacts with EQTN. Interacts with HGS. Interacts with KCNB1 (via N-terminus); reduces the voltage-dependent potassium channel KCNB1 activity in pancreatic beta cells. Interacts with OTOF. Interacts with RIMS1. Interacts with SNAPIN. Interacts with STXBP6. Interacts with TRIM9. Interacts with ZDHHC13 (via ANK repeats). Interacts with ZDHHC17 (via ANK repeats). Associates with the BLOC-1 complex. Interacts with PLCL1 (via C2 domain). Interacts with PRRT2; this interaction may impair the formation of the SNARE complex. Interacts with alpha-synuclein/SNCA. Interacts with PRPH2. Interacts with ROM1. Interacts with STX3.
messages: Photoreceptor inner segment
messages: synaptosome
messages: t-SNARE involved in the molecular regulation of neurotransmitter release. Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.

9940:LOC101115420
gene id: 9940:LOC101115420
uniprot id: W5PWG8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9940:GLDN
gene id: 9940:GLDN
uniprot id: A0A6P3E697
uniprot id: W5QII9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A51
gene id: 9940:SLC25A51
uniprot id: A0A6P3E932
uniprot id: A0A6P3TBX8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAK16
gene id: 9940:MAK16
uniprot id: W5NQE1
names: Similarity
messages: Belongs to the MAK16 family.

9940:SCAMP3
gene id: 9940:SCAMP3
uniprot id: W5P1K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9940:PSMD1
gene id: 9940:PSMD1
uniprot id: A0A6P3YGA1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM184C
gene id: 9940:TMEM184C
uniprot id: W5PDM6
names: Subcellular Location Annotation
messages: Membrane

9940:ITGB2
gene id: 9940:ITGB2
uniprot id: Q6ECI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the integrin beta chain family.
messages: Cell membrane
messages: Heterodimer of an alpha and a beta subunit. The ITGB2 beta subunit associates with the ITGAL, ITGAM, ITGAX or ITGAD alpha subunits. Found in a complex with CD177 and ITGAM/CD11b. Interacts with FGR. Interacts with COPS5 and RANBP9. Interacts with FLNA (via filamin repeats 4, 9, 12, 17, 19, 21, and 23). Interacts with THBD.
messages: Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin ITGAL/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages. In association with alpha subunit ITGAM/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils.
messages: Membrane raft

9940:HSPB3
gene id: 9940:HSPB3
uniprot id: W5P6E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

9940:FTCDNL1
gene id: 9940:FTCDNL1
uniprot id: A0A836D757
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RCAN1
gene id: 9940:RCAN1
uniprot id: Q6XXM7
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the RCAN family.
messages: Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
messages: Interacts with RAF1, PPP3R1 and PPP3CA.
messages: Phosphorylation increases its ability to inhibit calcineurin and decreases protein half-life.

9940:KRT25
gene id: 9940:KRT25
uniprot id: Q9BGM5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the intermediate filament family.
messages: Cytoplasm
messages: Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization (By similarity).
messages: Expressed in skin and wool follicle. Expression localized to the inner root sheath of wool follicle.
messages: Heterodimer of a type I and a type II keratin. Heterodimer with type II keratin KRT5 leading to the formation of keratin intermediate filament (KIF) network. Interacts with KRT6A to form filaments.
messages: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).

9940:DNAH12
gene id: 9940:DNAH12
uniprot id: W5PWU4
names: Similarity
messages: Belongs to the dynein heavy chain family.

9940:MAGT1
gene id: 9940:MAGT1
uniprot id: W5QAQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:MALL
gene id: 9940:MALL
uniprot id: W5PXT6
names: Subcellular Location Annotation
messages: Membrane

9940:OXR1
gene id: 9940:OXR1
uniprot id: W5Q149
names: Similarity
messages: Belongs to the OXR1 family.

9940:TIMM8A
gene id: 9940:TIMM8A
uniprot id: A0A6P3EFD6
uniprot id: W5NU43
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9940:STC1
gene id: 9940:STC1
uniprot id: W5PJZ9
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9940:LAMTOR2
gene id: 9940:LAMTOR2
uniprot id: A0A6P3E640
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NRP2
gene id: 9940:NRP2
uniprot id: W5QAQ4
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:HOOK1
gene id: 9940:HOOK1
uniprot id: A0A6P3YEY9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:KIN
gene id: 9940:KIN
uniprot id: W5PWH7
names: Similarity
messages: Belongs to the KIN17 family.

9940:MAGOH
gene id: 9940:MAGOH
uniprot id: A0A6P3DYT4
uniprot id: A0A6P7DNV8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mago nashi family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNT2
gene id: 9940:CCNT2
uniprot id: A0A6P3TCN8
uniprot id: W5PNN9
names: Caution
names: Similarity
messages: Belongs to the cyclin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC35F6
gene id: 9940:SLC35F6
uniprot id: W5QCF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

9940:METTL8
gene id: 9940:METTL8
uniprot id: W5NVW6
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9940:PSMA4
gene id: 9940:PSMA4
uniprot id: W5NS93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9940:C14H16orf46
gene id: 9940:C14H16orf46
uniprot id: A0A6P7EUC7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUP35
gene id: 9940:NUP35
uniprot id: A0A6P3E9J6
uniprot id: W5Q5H5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nuclear pore complex

9940:ICOS
gene id: 9940:ICOS
uniprot id: W5QAC8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

9940:ASB15
gene id: 9940:ASB15
uniprot id: A0A6P3E543
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLCO1C1
gene id: 9940:SLCO1C1
uniprot id: W5QGV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:CAPN6
gene id: 9940:CAPN6
uniprot id: W5Q8J4
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:SMOX
gene id: 9940:SMOX
uniprot id: A0A6P3EIR2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNE2
gene id: 9940:CCNE2
uniprot id: A0A6P3TVS8
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

9940:ETF1
gene id: 9940:ETF1
uniprot id: A0A6P3YLJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HADHA
gene id: 9940:HADHA
uniprot id: A0A6P9FQD3
uniprot id: B6UV59
names: Caution
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GAD2
gene id: 9940:GAD2
uniprot id: W5P462
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9940:FAM3C
gene id: 9940:FAM3C
uniprot id: A0A6P7E2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9940:MRPL27
gene id: 9940:MRPL27
uniprot id: A0A6P3E813
uniprot id: W5P3H6
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAN1A2
gene id: 9940:MAN1A2
uniprot id: A0A6P3DYT8
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DAB2
gene id: 9940:DAB2
uniprot id: A0A6P3TCK1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AKAP10
gene id: 9940:AKAP10
uniprot id: A0A835ZWW1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL15
gene id: 9940:IL15
uniprot id: Q9XSJ6
uniprot id: W5PRB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Cytokine that plays a major role in the development of inflammatory and protective immune responses to microbial invaders and parasites by modulating immune cells of both the innate and adaptive immune systems. Stimulates the proliferation of natural killer cells, T-cells and B-cells and promotes the secretion of several cytokines. In monocytes, induces the production of IL8 and monocyte chemotactic protein 1/CCL2, two chemokines that attract neutrophils and monocytes respectively to sites of infection. Unlike most cytokines, which are secreted in soluble form, IL15 is expressed in association with its high affinity IL15RA on the surface of IL15-producing cells and delivers signals to target cells that express IL2RB and IL2RG receptor subunits. Binding to its receptor triggers the phosphorylation of JAK1 and JAK3 and the recruitment and subsequent phosphorylation of signal transducer and activator of transcription-3/STAT3 and STAT5 (By similarity). In mast cells, induces the rapid tyrosine phosphorylation of STAT6 and thereby controls mast cell survival and release of cytokines such as IL4 (By similarity).
messages: Secreted

9940:MCP-3
gene id: 9940:MCP-3
uniprot id: O46683
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family. Granzyme subfamily.
messages: Cytoplasmic granule
messages: Secreted

9940:TTPA
gene id: 9940:TTPA
uniprot id: A0A6P9FRF9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFAP43
gene id: 9940:CFAP43
uniprot id: W5PA43
names: Similarity
messages: Belongs to the CFAP43 family.

9940:PADI3
gene id: 9940:PADI3
uniprot id: O02849
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm
messages: Found in wool follicles, keratinizing epithelia of the ruminal mucosa, embryonic hoof and tongue filiform papillae.
messages: The N-terminus is blocked.

9940:NUDT12
gene id: 9940:NUDT12
uniprot id: A0A6P3TE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9940:C11H17orf58
gene id: 9940:C11H17orf58
uniprot id: A0A6P3EJ02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EID1
gene id: 9940:EID1
uniprot id: W5NS15
names: Subcellular Location Annotation
messages: Nucleus

9940:LAPTM5
gene id: 9940:LAPTM5
uniprot id: W5NVL1
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

9940:AP5S1
gene id: 9940:AP5S1
uniprot id: A0A6P3EKG0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121627
gene id: 9940:LOC101121627
uniprot id: W5P9I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SPTLC2
gene id: 9940:SPTLC2
uniprot id: W5NX59
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

9940:TSPAN13
gene id: 9940:TSPAN13
uniprot id: A0A6P3EBR7
uniprot id: W5PGM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DOCK4
gene id: 9940:DOCK4
uniprot id: A0A836AA49
uniprot id: W5NY92
names: Caution
names: Similarity
messages: Belongs to the DOCK family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRP
gene id: 9940:GRP
uniprot id: A0A836CR47
uniprot id: P47851
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bombesin/neuromedin-B/ranatensin family.
messages: Induces an itch response through activation of receptors present on mast cells, triggering mast cell degranulation.
messages: Secreted
messages: Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior (By similarity). Contributes primarily to nonhistaminergic itch sensation (By similarity). In one study, shown to act in the amygdala as part of an inhibitory network which inhibits memory specifically related to learned fear (By similarity). In another study, shown to act on vasoactive intestinal peptide (VIP)-expressing cells in the auditory cortex, most likely via extrasynaptic diffusion from local and long-range sources, to mediate disinhibition of glutamatergic cells via VIP cell-specific GRPR signaling which leads to enhanced auditory fear memories (By similarity). Contributes to the regulation of food intake (By similarity). Inhibits voltage-gated sodium channels but enhances voltage-gated potassium channels in hippocampal neurons (By similarity). Induces sighing by acting directly on the pre-Botzinger complex, a cluster of several thousand neurons in the ventrolateral medulla responsible for inspiration during respiratory activity (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: neuron projection
messages: secretory vesicle lumen

9940:LOC101104530
gene id: 9940:LOC101104530
uniprot id: A0A6P3EC08
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC106990122
gene id: 9940:LOC106990122
uniprot id: W5PMM4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:LMO4
gene id: 9940:LMO4
uniprot id: A0A6P3E449
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNRNPH2
gene id: 9940:HNRNPH2
uniprot id: A0A6P3ESJ1
uniprot id: A0A6P3TBF0
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleoplasm

9940:SLC39A8
gene id: 9940:SLC39A8
uniprot id: W5PUQ1
names: Subcellular Location Annotation
messages: Membrane

9940:RAD21
gene id: 9940:RAD21
uniprot id: W5PKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9940:ZNF449
gene id: 9940:ZNF449
uniprot id: A0A6P3ESB7
uniprot id: A0A6P7DJT2
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC38A1
gene id: 9940:SLC38A1
uniprot id: A0A6P7DY72
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113467
gene id: 9940:LOC101113467
uniprot id: A0A6P3E6E2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB7A
gene id: 9940:RAB7A
uniprot id: A0A6P3CX02
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KEF53 p08
gene id: 9940:KEF53_p08
uniprot id: A0A0E3M1Y2
uniprot id: O78752
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with DNAJC30; interaction is direct (By similarity).
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9940:EMC8
gene id: 9940:EMC8
uniprot id: A0A6P3EKX9
uniprot id: W5PPA8
names: Caution
names: Similarity
messages: Belongs to the EMC8/EMC9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109377
gene id: 9940:LOC101109377
uniprot id: A0A6P3EBN5
uniprot id: A0A6P7EN58
names: Caution
names: Similarity
messages: Belongs to the aldo/keto reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL23A
gene id: 9940:RPL23A
uniprot id: A0A6P3CX48
uniprot id: D4P8H6
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CST3
gene id: 9940:CST3
uniprot id: A0A6P9FQW5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HTR1F
gene id: 9940:HTR1F
uniprot id: W5NT63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

9940:GNG4
gene id: 9940:GNG4
uniprot id: A0A6P3TEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9940:LOC101109343
gene id: 9940:LOC101109343
uniprot id: W5NQL8
names: Similarity
messages: Belongs to the serpin family.

9940:CFAP91
gene id: 9940:CFAP91
uniprot id: W5QEV6
names: Similarity
messages: Belongs to the CFAP91 family.

9940:LOC101119111
gene id: 9940:LOC101119111
uniprot id: A0A836AG40
uniprot id: W5QEB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:CDPF1
gene id: 9940:CDPF1
uniprot id: A0A6P3ECL4
names: Caution
names: Similarity
messages: Belongs to the CDPF1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGTPBP1
gene id: 9940:AGTPBP1
uniprot id: W5PGD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9940:DRGX
gene id: 9940:DRGX
uniprot id: W5NV96
names: Subcellular Location Annotation
messages: Nucleus

9940:PGLYRP4
gene id: 9940:PGLYRP4
uniprot id: W5NQG3
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9940:MMP19
gene id: 9940:MMP19
uniprot id: A0A6P3E7Y6
uniprot id: W5PMR2
names: Similarity
messages: Belongs to the peptidase M10A family.

9940:CNOT11
gene id: 9940:CNOT11
uniprot id: A0A836AGI7
uniprot id: W5PUR1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEBPG
gene id: 9940:CEBPG
uniprot id: A0A6P7ERF9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FGF6
gene id: 9940:FGF6
uniprot id: W5PK90
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9940:SLTM
gene id: 9940:SLTM
uniprot id: A0A6P3YK62
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AQP1
gene id: 9940:AQP1
uniprot id: P56401
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Detected in fetal kidney (at protein level). Detected in fetal kidney.
messages: Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
messages: Homotetramer (By similarity). Interacts with EPHB2; involved in endolymph production in the inner ear. Identified in a complex with STOM (By similarity).
messages: Pharmacologically inhibited by submillimolar concentrations of mercury.

9940:LOC101102857
gene id: 9940:LOC101102857
uniprot id: A0A6P7EG13
uniprot id: W5PD15
names: Caution
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9940:MED11
gene id: 9940:MED11
uniprot id: A0A6P3ED31
uniprot id: W5PCX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL1
gene id: 9940:ARL1
uniprot id: B2LYL2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9940:PPP1R12A
gene id: 9940:PPP1R12A
uniprot id: A0A6P3TL67
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: stress fiber

9940:LOC101109774
gene id: 9940:LOC101109774
uniprot id: A0A6P3EHF8
uniprot id: W5P6Q9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRTAP6-1
gene id: 9940:KRTAP6-1
uniprot id: A0A836AH50
uniprot id: Q02958
uniprot id: Q53YS7
names: Caution
names: Developmental Stage
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KRTAP type 6 family.
messages: In the wool cortex, wool keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant wool shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of wool keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with wool keratins.
messages: The KAP6 proteins are first expressed in differentiating hair shaft keratinocytes, a considerable distance above the proliferative zone of the follicle bulb.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM255A
gene id: 9940:TMEM255A
uniprot id: A0A6P3ESM9
uniprot id: W5PU27
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UGT8
gene id: 9940:UGT8
uniprot id: A0A836A6J5
uniprot id: W5Q9Z6
names: Caution
names: Similarity
messages: Belongs to the UDP-glycosyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FABP1
gene id: 9940:FABP1
uniprot id: A0A6P3E9X5
uniprot id: W5QHV3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOC3L
gene id: 9940:NOC3L
uniprot id: W5P1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

9940:BCL6B
gene id: 9940:BCL6B
uniprot id: A0A6P3E9Z6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POT1
gene id: 9940:POT1
uniprot id: A0A6P3E919
uniprot id: A0A6P3TN07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: telomere

9940:CTNNBL1
gene id: 9940:CTNNBL1
uniprot id: W5Q9P0
names: Subcellular Location Annotation
messages: Nucleus

9940:ARCN1
gene id: 9940:ARCN1
uniprot id: A0A6P3EK90
uniprot id: W5PLQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105605457
gene id: 9940:LOC105605457
uniprot id: A0A6P7EGT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AJAP1
gene id: 9940:AJAP1
uniprot id: W5PY23
names: Subcellular Location Annotation
messages: Membrane

9940:SLC25A12
gene id: 9940:SLC25A12
uniprot id: A0A6P3E8K2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105615211
gene id: 9940:LOC105615211
uniprot id: A0A836AFR0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VEZT
gene id: 9940:VEZT
uniprot id: W5Q3B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

9940:ASIC1
gene id: 9940:ASIC1
uniprot id: W5Q9I4
uniprot id: W5Q9I5
names: Subcellular Location Annotation
messages: Membrane

9940:TXLNG
gene id: 9940:TXLNG
uniprot id: A0A6P3EH23
uniprot id: W5PUJ8
names: Caution
names: Similarity
messages: Belongs to the taxilin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC30A6
gene id: 9940:SLC30A6
uniprot id: W5PLW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9940:SLC8A3
gene id: 9940:SLC8A3
uniprot id: W5QJ75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9940:GFOD2
gene id: 9940:GFOD2
uniprot id: A0A6P3EJI7
uniprot id: A0A6P7ER65
names: Caution
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105276
gene id: 9940:LOC101105276
uniprot id: A0A6P3ELD4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105613289
gene id: 9940:LOC105613289
uniprot id: A0A6P3YKP1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGC
gene id: 9940:PGC
uniprot id: W5NX00
names: Function
names: Similarity
messages: Belongs to the peptidase A1 family.
messages: Hydrolyzes a variety of proteins.

9940:F9
gene id: 9940:F9
uniprot id: W5PLL2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:LOC101110546
gene id: 9940:LOC101110546
uniprot id: A0A836A0U0
uniprot id: W5PMC5
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBIAD1
gene id: 9940:UBIAD1
uniprot id: A0A6P3EJN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DAP3
gene id: 9940:DAP3
uniprot id: A0A6P3E635
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RRAGA
gene id: 9940:RRAGA
uniprot id: A0A6P3CWW6
uniprot id: C5IJ87
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STT3A
gene id: 9940:STT3A
uniprot id: A0A6P3ED77
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSIP1
gene id: 9940:PSIP1
uniprot id: B8Y8S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

9940:ZBTB1
gene id: 9940:ZBTB1
uniprot id: A0A6P3TPE4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C17H12orf43
gene id: 9940:C17H12orf43
uniprot id: A0A6P3EME4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIF20A
gene id: 9940:KIF20A
uniprot id: A0A6P3E4S3
uniprot id: W5Q2V6
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CTSV
gene id: 9940:CTSV
uniprot id: A0A6P3E0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9940:AKT1
gene id: 9940:AKT1
uniprot id: C5IJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.
messages: Cytoplasm

9940:GTF2F2
gene id: 9940:GTF2F2
uniprot id: A0A6P3E9C0
uniprot id: W5PCK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZWILCH
gene id: 9940:ZWILCH
uniprot id: A0A836A2M5
uniprot id: W5QA15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: kinetochore

9940:GJA9
gene id: 9940:GJA9
uniprot id: W5PIQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9940:RGS2
gene id: 9940:RGS2
uniprot id: W5PIT6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

9940:CT83
gene id: 9940:CT83
uniprot id: A0A6P3ENH7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLAT
gene id: 9940:PLAT
uniprot id: W5NYU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:ACLY
gene id: 9940:ACLY
uniprot id: Q2TCH3
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated at Lys-540, Lys-546 and Lys-554 by KAT2B/PCAF (By similarity). Acetylation is promoted by glucose and stabilizes the protein, probably by preventing ubiquitination at the same sites (By similarity). Acetylation promotes de novo lipid synthesis (By similarity). Deacetylated by SIRT2 (By similarity).
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: ISGylated.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.
messages: Phosphorylated by PKA and GSK3 in a sequential manner; phosphorylation results in activation of its activity (By similarity). Phosphorylation on Thr-447 and Ser-451 depends on the phosphorylation state of Ser-455 (By similarity). Phosphorylation on Ser-455 is decreased by prior phosphorylation on the other 2 residues (By similarity).
messages: Phosphorylation results in activation of its activity (By similarity). Glucose 6-phosphate, fructose 6-phosphate, fructose 2,6-bisphosphate, ribulose 5-phosphate, and fructose 1,6-bisphosphate also act as activators (By similarity).
messages: Ubiquitinated at Lys-540, Lys-546 and Lys-554 by the BCR(KLHL25) E3 ubiquitin ligase complex and UBR4, leading to its degradation (By similarity). Ubiquitination is probably inhibited by acetylation at same site (By similarity). BCR(KLHL25)-mediated degradation of ACLY promotes fatty acid oxidation and is required for differentiation of inducible regulatory T (iTreg) cells (By similarity).
messages: cytosol

9940:TNFRSF9
gene id: 9940:TNFRSF9
uniprot id: A0A6P3EE71
uniprot id: W5PKG1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRE11
gene id: 9940:MRE11
uniprot id: W5NVN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

9940:IL26
gene id: 9940:IL26
uniprot id: W5NUV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9940:NARF
gene id: 9940:NARF
uniprot id: W5Q4R4
names: Similarity
messages: Belongs to the NARF family.

9940:SLC6A7
gene id: 9940:SLC6A7
uniprot id: W5P9Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9940:LOC101108252
gene id: 9940:LOC101108252
uniprot id: W5PC84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CD59
gene id: 9940:CD59
uniprot id: A0A6P3YM37
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SIN3A
gene id: 9940:SIN3A
uniprot id: A0A6P3YRY4
names: Subcellular Location Annotation
messages: Nucleus

9940:SF3B4
gene id: 9940:SF3B4
uniprot id: A0A6P3DYX0
uniprot id: W5QHR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHMP4C
gene id: 9940:CHMP4C
uniprot id: A0A836ABB3
uniprot id: W5PZJ0
names: Caution
names: Similarity
messages: Belongs to the SNF7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITIH3
gene id: 9940:ITIH3
uniprot id: W5NSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9940:RHEB
gene id: 9940:RHEB
uniprot id: A0A6P9FQL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109269
gene id: 9940:LOC101109269
uniprot id: A0A6P3E4Q1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TOB1
gene id: 9940:TOB1
uniprot id: A0A6P3TWX7
uniprot id: A0A6P3YL74
names: Caution
names: Similarity
messages: Belongs to the BTG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMPD1
gene id: 9940:SMPD1
uniprot id: C8BKD7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

9940:LOC101110545
gene id: 9940:LOC101110545
uniprot id: W5PE14
names: Similarity
messages: Belongs to the MHC class II family.

9940:ZFX
gene id: 9940:ZFX
uniprot id: A0A6P3TFE5
uniprot id: A0A6P3YTP4
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL53
gene id: 9940:MRPL53
uniprot id: W5PT24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

9940:SPSB1
gene id: 9940:SPSB1
uniprot id: A0A6P3EI35
names: Similarity
messages: Belongs to the SPSB family.

9940:LOC101107284
gene id: 9940:LOC101107284
uniprot id: W5PRN7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PLA2G5
gene id: 9940:PLA2G5
uniprot id: A0A836AC67
uniprot id: W5NS89
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNDBP1
gene id: 9940:CCNDBP1
uniprot id: W5QHC4
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

9940:SQLE
gene id: 9940:SQLE
uniprot id: A0A6P3CWQ1
uniprot id: A6YQW0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GGTA1
gene id: 9940:GGTA1
uniprot id: Q6SVU1
uniprot id: W5PYG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9940:IFNE
gene id: 9940:IFNE
uniprot id: A0A6P3TM81
uniprot id: W5PGC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MPPED2
gene id: 9940:MPPED2
uniprot id: A0A6P7EW68
names: Similarity
messages: Belongs to the UPF0046 family.

9940:LTA4H
gene id: 9940:LTA4H
uniprot id: A0A6P3EAV9
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LPXN
gene id: 9940:LPXN
uniprot id: W5PN77
names: Similarity
messages: Belongs to the paxillin family.

9940:B4GALT3
gene id: 9940:B4GALT3
uniprot id: A0A6P3E689
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL6
gene id: 9940:RPL6
uniprot id: W5P3J0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

9940:GGNBP2
gene id: 9940:GGNBP2
uniprot id: A0A6P3TR97
names: Caution
names: Function
messages: May be involved in spermatogenesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPINK7
gene id: 9940:SPINK7
uniprot id: A0A836D386
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MOB1B
gene id: 9940:MOB1B
uniprot id: A0A6P3YM01
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GHSR
gene id: 9940:GHSR
uniprot id: A0A6P7DX51
uniprot id: Q8MHZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PMP22
gene id: 9940:PMP22
uniprot id: A0A6P3THK8
uniprot id: C5IS97
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KLHL6
gene id: 9940:KLHL6
uniprot id: A0A6P3E839
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GATA3
gene id: 9940:GATA3
uniprot id: F8WQV3
names: Subcellular Location Annotation
messages: Nucleus

9940:BCAP29
gene id: 9940:BCAP29
uniprot id: A0A6P3E8U8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDCD10
gene id: 9940:PDCD10
uniprot id: A0A6P3TMA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9940:RAG1
gene id: 9940:RAG1
uniprot id: W5PL78
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

9940:LHFPL6
gene id: 9940:LHFPL6
uniprot id: A0A6P3YJL5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHFR
gene id: 9940:CHFR
uniprot id: W5PHM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHFR family.
messages: PML body

9940:LCAT
gene id: 9940:LCAT
uniprot id: C5IS96
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9940:TNP1
gene id: 9940:TNP1
uniprot id: A0A836AE57
uniprot id: P22613
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the nuclear transition protein 1 family.
messages: Chromosome
messages: Nucleus
messages: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
messages: Testis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C23H18orf21
gene id: 9940:C23H18orf21
uniprot id: A0A6P3YPS3
names: Caution
names: Similarity
messages: Belongs to the UPF0711 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ENPP4
gene id: 9940:ENPP4
uniprot id: A0A6P7D8A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

9940:ANTKMT
gene id: 9940:ANTKMT
uniprot id: A0A6P3EQL7
uniprot id: W5PVW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF7
gene id: 9940:RNF7
uniprot id: A0A6P3E0G9
uniprot id: W5P9B7
names: Caution
names: Similarity
messages: Belongs to the RING-box family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDC42SE2
gene id: 9940:CDC42SE2
uniprot id: A0A6P3YHY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Interacts with CDC42 (in GTP-bound form). Interacts weakly with RAC1 and not at all with RHOA.
messages: Membrane
messages: Probably involved in the organization of the actin cytoskeleton by acting downstream of CDC42, inducing actin filament assembly. Alters CDC42-induced cell shape changes. In activated T-cells, may play a role in CDC42-mediated F-actin accumulation at the immunological synapse. May play a role in early contractile events in phagocytosis in macrophages.
messages: cytoskeleton

9940:ZFAND2B
gene id: 9940:ZFAND2B
uniprot id: A0A6P3E1R6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAD54L2
gene id: 9940:RAD54L2
uniprot id: A0A6P3EC99
uniprot id: W5PBH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117955
gene id: 9940:LOC101117955
uniprot id: P68302
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.
messages: Interacts with EOLA1.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.

9940:DUOXA1
gene id: 9940:DUOXA1
uniprot id: W5QIS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9940:BMPR2
gene id: 9940:BMPR2
uniprot id: V9HXG2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

9940:LOC101102391
gene id: 9940:LOC101102391
uniprot id: W5PSV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:MYOG
gene id: 9940:MYOG
uniprot id: D3YKV7
names: Subcellular Location Annotation
messages: Nucleus

9940:DLD
gene id: 9940:DLD
uniprot id: A0A6P3EBV7
uniprot id: W5PB39
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: acrosome
messages: flagellum

9940:PDGFB
gene id: 9940:PDGFB
uniprot id: Q95229
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Antiparallel homodimer; disulfide-linked. Antiparallel heterodimer with PDGFA; disulfide-linked. The PDGFB homodimer interacts with PDGFRA and PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. The heterodimer composed of PDGFA and PDGFB interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB. Interacts with XLKD1 (By similarity). Interacts with LRP1 (By similarity). Interacts with SORL1 (via the N-terminal ectodomain) (By similarity).
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
messages: Secreted

9940:SCGB2A2
gene id: 9940:SCGB2A2
uniprot id: A0A6P3EQJ2
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HCST
gene id: 9940:HCST
uniprot id: A0A6P3TUD9
uniprot id: A0A6P3TVN0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IRF6
gene id: 9940:IRF6
uniprot id: Q9N136
uniprot id: W5PT47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:LOC101121387
gene id: 9940:LOC101121387
uniprot id: A0A836ADP7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIAS
gene id: 9940:LIAS
uniprot id: A0A6P3E5F3
uniprot id: W5PQ59
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANKFY1
gene id: 9940:ANKFY1
uniprot id: A0A836CY98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRT17
gene id: 9940:KRT17
uniprot id: U3MXA9
names: Similarity
messages: Belongs to the intermediate filament family.

9940:SMAD1
gene id: 9940:SMAD1
uniprot id: A0A6P3EHN1
uniprot id: A0A835ZPQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107266
gene id: 9940:LOC101107266
uniprot id: A0A6P3E775
uniprot id: W5QHN1
names: Caution
names: Similarity
messages: Belongs to the SNF7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC18B1
gene id: 9940:SLC18B1
uniprot id: W5PYN2
names: Subcellular Location Annotation
messages: Membrane

9940:DBX2
gene id: 9940:DBX2
uniprot id: W5QEA0
names: Subcellular Location Annotation
messages: Nucleus

9940:PRPF38A
gene id: 9940:PRPF38A
uniprot id: A0A6P3DY98
uniprot id: W5P5R7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:F11R
gene id: 9940:F11R
uniprot id: A0A6P3E4M9
uniprot id: W5PHN9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:ALDH2
gene id: 9940:ALDH2
uniprot id: A0A6P3EHX6
uniprot id: W5PLV2
names: Caution
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC89
gene id: 9940:CCDC89
uniprot id: A0A6P3TCP0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FOXP1
gene id: 9940:FOXP1
uniprot id: A0A6P3T779
names: Subcellular Location Annotation
messages: Nucleus

9940:MAPK14
gene id: 9940:MAPK14
uniprot id: A0A6P3CX87
uniprot id: B7TJ15
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAT1
gene id: 9940:STAT1
uniprot id: A0A6P3CX40
uniprot id: C8BKE1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DCBLD2
gene id: 9940:DCBLD2
uniprot id: A0A6P3E032
uniprot id: W5Q8T4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UGT1A1
gene id: 9940:UGT1A1
uniprot id: F1CGV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:TSR2
gene id: 9940:TSR2
uniprot id: A0A6P3EMV3
uniprot id: W5P914
names: Caution
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD247
gene id: 9940:CD247
uniprot id: P29329
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CD3Z/FCER1G family.
messages: Cell membrane
messages: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. CD3Z ITAMs phosphorylation creates multiple docking sites for the protein kinase ZAP70 leading to ZAP70 phosphorylation and its conversion into a catalytically active enzyme. Plays an important role in intrathymic T-cell differentiation. Additionally, participates in the activity-dependent synapse formation of retinal ganglion cells (RGCs) in both the retina and dorsal lateral geniculate nucleus (dLGN).
messages: Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8.
messages: The ITAM domains mediate interaction with SHB.
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta. Interacts with SLA. Interacts with TRAT1. Interacts with DOCK2. Interacts with SLA2. Interacts with SHB. Interacts with ZAP70. Interacts (tyrosine phosphorylated) with SHC1 (via SH2 domain). Interacts with PTPRC. Interacts with CRK; this interaction regulates CD3Z phosphorylation. Interacts (on T cell side) with CD81, ICAM1 and CD9 at immunological synapses between antigen-presenting cells and T cells. Interacts with CD160. Interacts with LY6E. Interacts with LY6E (By similarity). The signaling subunit of immunoglobulin gamma (IgG) Fc receptor complex. As a homodimer or a heterodimer with FCER1G, associates with the ligand binding subunit FCGR3A (via transmembrane domain); this interaction is a prerequisite for Fc receptor complex expression on the cell surface.

9940:IDO2
gene id: 9940:IDO2
uniprot id: W5NW87
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

9940:NECAP1
gene id: 9940:NECAP1
uniprot id: A0A836A927
uniprot id: W5NWV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: clathrin-coated vesicle membrane

9940:SPRING1
gene id: 9940:SPRING1
uniprot id: A0A6P3EMA6
uniprot id: W5P6F6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BROX
gene id: 9940:BROX
uniprot id: A0A6P3TIN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BROX family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NTAN1
gene id: 9940:NTAN1
uniprot id: A0A6P3ELI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPA3
gene id: 9940:CPA3
uniprot id: A0A6P3E753
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBAP1
gene id: 9940:UBAP1
uniprot id: A0A6P3E5R5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SOWAHC
gene id: 9940:SOWAHC
uniprot id: A0A6P3TKR3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:P4HA1
gene id: 9940:P4HA1
uniprot id: W5PBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9940:ENKUR
gene id: 9940:ENKUR
uniprot id: W5P037
names: Subcellular Location Annotation
messages: cilium axoneme

9940:ZPBP2
gene id: 9940:ZPBP2
uniprot id: A0A6P3TI69
uniprot id: W5PRG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LAMTOR4
gene id: 9940:LAMTOR4
uniprot id: A0A6P3ER19
names: Caution
names: Similarity
messages: Belongs to the LAMTOR4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SRP19
gene id: 9940:SRP19
uniprot id: A0A6P3EEF6
uniprot id: W5Q3G3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP19 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC44A5
gene id: 9940:SLC44A5
uniprot id: W5PST6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

9940:LOC101116648
gene id: 9940:LOC101116648
uniprot id: W5NT60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TNP2
gene id: 9940:TNP2
uniprot id: W5P9A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 2 family.
messages: Nucleus
messages: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

9940:LOC101102729
gene id: 9940:LOC101102729
uniprot id: W5Q9C5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Membrane

9940:LOC101110966
gene id: 9940:LOC101110966
uniprot id: W5PV97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101103561
gene id: 9940:LOC101103561
uniprot id: W5NT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC105614315
gene id: 9940:LOC105614315
uniprot id: A0A6P3YLY0
uniprot id: W5PRJ6
names: Caution
names: Similarity
messages: Belongs to the aldo/keto reductase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFB2
gene id: 9940:NDUFB2
uniprot id: A0A8N7XJB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CFI
gene id: 9940:CFI
uniprot id: A0A6P3EA58
uniprot id: W5P5I3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL19
gene id: 9940:RPL19
uniprot id: A0A6P3EIR5
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAF6
gene id: 9940:TRAF6
uniprot id: A0A6P3YR70
uniprot id: W5QCP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cell cortex

9940:DNAH7
gene id: 9940:DNAH7
uniprot id: W5PYR8
names: Similarity
messages: Belongs to the dynein heavy chain family.

9940:BTK
gene id: 9940:BTK
uniprot id: A0A835ZLT1
uniprot id: W5NU60
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAT5A
gene id: 9940:STAT5A
uniprot id: P42231
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the transcription factor STAT family.
messages: By prolactin.
messages: Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation.
messages: Cytoplasm
messages: Forms a homodimer or a heterodimer with a related family member. Binds NR3C1. Interacts with NCOA1 and SOCS7. Interacts with ERBB4 (By similarity). Interacts with EBF4.
messages: Found in mammary gland and, in lesser extent, in ovary, thymus, spleen, kidney, lung, muscle and adrenal gland.
messages: ISGylated.
messages: Nucleus
messages: Tyrosine phosphorylated in response to KITLG/SCF, IL2, IL3, IL7, IL15, CSF2/GMCSF, GH1, PRL, EPO and THPO (By similarity). Activated KIT promotes phosphorylation on tyrosine residues and subsequent translocation to the nucleus (By similarity). Tyrosine phosphorylated in response to constitutively activated FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Tyrosine phosphorylation is required for DNA-binding activity and dimerization. Serine phosphorylation is also required for maximal transcriptional activity (By similarity). Tyrosine phosphorylated in response to signaling via activated FLT3; wild-type FLT3 results in much weaker phosphorylation than constitutively activated mutant FLT3. Alternatively, can be phosphorylated by JAK2 at Tyr-694 (By similarity).

9940:PRPS1L1
gene id: 9940:PRPS1L1
uniprot id: A0A836A7D5
uniprot id: W5PE70
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EAF2
gene id: 9940:EAF2
uniprot id: A0A6P3DZM8
uniprot id: W5QFR2
names: Caution
names: Similarity
messages: Belongs to the EAF family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MORN4
gene id: 9940:MORN4
uniprot id: A0A6P3T4T7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OS9
gene id: 9940:OS9
uniprot id: W5P6E0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

9940:DAD1
gene id: 9940:DAD1
uniprot id: A0A6P3EAU1
uniprot id: W5QDT3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACKR3
gene id: 9940:ACKR3
uniprot id: W5NQ57
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:RMI1
gene id: 9940:RMI1
uniprot id: A0A6P3TBR7
uniprot id: A0A6P3YFS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSPA13
gene id: 9940:HSPA13
uniprot id: A0A6P3E4S1
uniprot id: W5Q411
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TOP2A
gene id: 9940:TOP2A
uniprot id: A0A6P3TX24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus
messages: nucleoplasm

9940:AKIRIN2
gene id: 9940:AKIRIN2
uniprot id: A0A6P3CXD7
uniprot id: G3LHX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRP6
gene id: 9940:LRP6
uniprot id: A0A6P3ECC1
uniprot id: W5QI85
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMAD2
gene id: 9940:SMAD2
uniprot id: A0A6P3YNX4
uniprot id: A0A6P7DD43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120200
gene id: 9940:LOC101120200
uniprot id: A0A835ZVV9
uniprot id: W5QFN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BAC5
gene id: 9940:BAC5
uniprot id: P79362
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: BAC5 sequence consists almost exclusively of X-P-P-Y repeats.
messages: Belongs to the cathelicidin family.
messages: Binds to the lipid A moiety of bacterial lipipolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Potent antimicrobial activity (By similarity).
messages: Elastase is responsible for its maturation.
messages: Secreted

9940:ATG5
gene id: 9940:ATG5
uniprot id: A0A6P3TGE0
uniprot id: A0A6P3TPV8
uniprot id: W5PNH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

9940:MT3
gene id: 9940:MT3
uniprot id: Q8MKE4
names: Function
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Binds heavy metals. Contains five zinc and one copper atoms per polypeptide chain and only a negligible amount of cadmium (By similarity).

9940:LOC101121681
gene id: 9940:LOC101121681
uniprot id: A0A836AHE5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STIP1
gene id: 9940:STIP1
uniprot id: A0A6P3EDB9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLF2
gene id: 9940:SLF2
uniprot id: A0A6P3EDM7
uniprot id: W5Q2L7
names: Caution
names: Similarity
messages: Belongs to the FAM178 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KEF53 p07
gene id: 9940:KEF53_p07
uniprot id: H1ZZ70
uniprot id: O21619
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome (By similarity). The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (PubMed:27654913).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9940:ZBTB25
gene id: 9940:ZBTB25
uniprot id: A0A6P3EFB8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBX21
gene id: 9940:TBX21
uniprot id: W5PES9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:SCGB1A1
gene id: 9940:SCGB1A1
uniprot id: D6C4M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

9940:MLF1
gene id: 9940:MLF1
uniprot id: A0A6P3TC46
uniprot id: W5NWV2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108428
gene id: 9940:LOC101108428
uniprot id: A0A6P3EC83
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUDT16
gene id: 9940:NUDT16
uniprot id: Q2V8X7
names: Cofactor
names: Developmental Stage
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. NUDT16 subfamily.
messages: Binds 3 or 4 divalent metal cations. Acts specifically on U8 snoRNA with magnesium as cofactor. Has broad substrate specificity with bound manganese or cobalt (in vitro).
messages: By steroid hormones.
messages: Cytoplasm
messages: Homodimer.
messages: NUDT16 mRNA concentrations are elevated 10-fold in the endometrium of sheep from day 5 to 9 of the estrous cycle and return to basal levels by day 11.
messages: Nucleus
messages: RNA-binding and decapping enzyme that catalyzes the cleavage of the cap structure of snoRNAs and mRNAs in a metal-dependent manner. Part of the U8 snoRNP complex that is required for the accumulation of mature 5.8S and 28S rRNA. Has diphosphatase activity and removes m7G and/or m227G caps from U8 snoRNA and leaves a 5'monophosphate on the RNA. Catalyzes also the cleavage of the cap structure on mRNAs. Does not hydrolyze cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG). Also hydrolysis m7G- and m227G U3-capped RNAs but with less efficiencies. Has broad substrate specificity with manganese or cobalt as cofactor and can act on various RNA species. Binds to the U8 snoRNA; metal is not required for RNA-binding. May play a role in the regulation of snoRNAs and mRNAs degradation. Acts also as a phosphatase; hydrolyzes the non-canonical purine nucleotides inosine diphosphate (IDP) and deoxyinosine diphosphate (dITP) as well as guanosine diphosphate (GDP), deoxyguanosine diphosphate (dGDP), xanthine diphosphate (XDP), inosine triphosphate (ITP) and deoxyinosine triphosphate (ITP) to their respective monophosphate derivatives and does not distinguish between the deoxy- and ribose forms. The order of activity with different substrates is IDP > dIDP >> GDP = dGDP > XDP = ITP = dITP. Binds strongly to GTP, ITP and XTP. Participates in the hydrolysis of dIDP/IDP and probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions (By similarity). Exhibits decapping activity towards NAD-capped RNAs and FAD-capped RNAs (By similarity). Exhibits decapping activity towards dpCoA-capped RNAs in vitro (By similarity).
messages: nucleolus
messages: nucleoplasm

9940:SLC1A1
gene id: 9940:SLC1A1
uniprot id: W5PV81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9940:PIGN
gene id: 9940:PIGN
uniprot id: A0A6P3TE49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

9940:ORMDL2
gene id: 9940:ORMDL2
uniprot id: A0A6P3EAU4
uniprot id: A0A6P3TK34
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPT2
gene id: 9940:CPT2
uniprot id: W5P878
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9940:CNOT8
gene id: 9940:CNOT8
uniprot id: A0A6P3E9S3
uniprot id: A0A6P3TH76
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AK2
gene id: 9940:AK2
uniprot id: W5QI77
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer.

9940:LOC101102512
gene id: 9940:LOC101102512
uniprot id: A0A6P3EKY5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SDC2
gene id: 9940:SDC2
uniprot id: A0A6P3YNA7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IDO1
gene id: 9940:IDO1
uniprot id: A0A6P3CX74
uniprot id: B6VEZ9
names: Caution
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OXSR1
gene id: 9940:OXSR1
uniprot id: A0A6P3EEF0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106638
gene id: 9940:LOC101106638
uniprot id: A0A6P3TIN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COMMD5
gene id: 9940:COMMD5
uniprot id: A0A6P3YN49
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HNRNPUL2
gene id: 9940:HNRNPUL2
uniprot id: W5Q5S5
names: Subcellular Location Annotation
messages: Nucleus

9940:ABHD1
gene id: 9940:ABHD1
uniprot id: A0A6P3EAS2
names: Caution
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LMBRD2
gene id: 9940:LMBRD2
uniprot id: A0A835ZYJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFRSF1B
gene id: 9940:TNFRSF1B
uniprot id: W5Q6X2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:IFT46
gene id: 9940:IFT46
uniprot id: W5PL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

9940:TFCP2
gene id: 9940:TFCP2
uniprot id: A0A6P3TJM4
uniprot id: W5Q7H8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STEAP1
gene id: 9940:STEAP1
uniprot id: A0A6P3EC00
names: Subcellular Location Annotation
messages: Membrane

9940:ATL3
gene id: 9940:ATL3
uniprot id: A0A835ZM39
uniprot id: W5NY07
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POU5F1
gene id: 9940:POU5F1
uniprot id: W5PJV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-5 subfamily.
messages: Nucleus

9940:SGF29
gene id: 9940:SGF29
uniprot id: A0A6P3TJP9
names: Subcellular Location Annotation
messages: Nucleus

9940:PPP1R2
gene id: 9940:PPP1R2
uniprot id: A0A6P3E7Z8
uniprot id: W5QGP7
names: Caution
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF146
gene id: 9940:RNF146
uniprot id: W5PCV4
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

9940:CENPM
gene id: 9940:CENPM
uniprot id: A0A6P3E8F8
uniprot id: W5QBT9
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1QTNF3
gene id: 9940:C1QTNF3
uniprot id: A0A6P3EDR1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SQSTM1
gene id: 9940:SQSTM1
uniprot id: A0A6P9FQM3
uniprot id: C5ISA9
names: Caution
names: Subcellular Location Annotation
messages: Lysosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: autophagosome

9940:ARL8B
gene id: 9940:ARL8B
uniprot id: C5IWT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: spindle

9940:FTO
gene id: 9940:FTO
uniprot id: A7UHZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fto family.
messages: Cytoplasm
messages: Nucleus speckle

9940:PFDN5
gene id: 9940:PFDN5
uniprot id: A0A6P3E7L1
uniprot id: W5Q4Z0
names: Caution
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGFG2
gene id: 9940:AGFG2
uniprot id: A0A6P3ER09
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ME1
gene id: 9940:ME1
uniprot id: B5SZL5
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9940:SEC23B
gene id: 9940:SEC23B
uniprot id: A0A6P3YLV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9940:GEMIN5
gene id: 9940:GEMIN5
uniprot id: A0A836A6Y4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104594
gene id: 9940:LOC101104594
uniprot id: A0A836CWF6
uniprot id: W5P935
names: Caution
names: Similarity
messages: Belongs to the strictosidine synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TGDS
gene id: 9940:TGDS
uniprot id: A0A6P3YNC4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARFGEF1
gene id: 9940:ARFGEF1
uniprot id: A0A6P3EHG1
uniprot id: W5NSV2
names: Caution
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:MTPN
gene id: 9940:MTPN
uniprot id: A0A6P3E495
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGM2L1
gene id: 9940:PGM2L1
uniprot id: W5PJJ5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9940:LOC101102756
gene id: 9940:LOC101102756
uniprot id: W5PRJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:MAGEF1
gene id: 9940:MAGEF1
uniprot id: A0A6P3E822
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF174
gene id: 9940:ZNF174
uniprot id: A0A6P3ELG1
uniprot id: A0A6P3T9M4
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PNPO
gene id: 9940:PNPO
uniprot id: W5PCU5
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

9940:DUSP6
gene id: 9940:DUSP6
uniprot id: W5Q228
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9940:DNAAF4
gene id: 9940:DNAAF4
uniprot id: A0A6P3EG33
uniprot id: A0A6P7E942
names: Caution
names: Subcellular Location Annotation
messages: Dynein axonemal particle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: neuron projection

9940:ANAPC16
gene id: 9940:ANAPC16
uniprot id: A0A6P3EEH9
uniprot id: A0A6P3ES15
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: kinetochore

9940:LOC101102541
gene id: 9940:LOC101102541
uniprot id: W5P3J0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

9940:LOC101106046
gene id: 9940:LOC101106046
uniprot id: W5NRP7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9940:CD5
gene id: 9940:CD5
uniprot id: A0A6P3TF51
uniprot id: W5Q3P2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UCP3
gene id: 9940:UCP3
uniprot id: R4TWY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:RPL9
gene id: 9940:RPL9
uniprot id: A0A6P3EA32
uniprot id: W5NTE7
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEBPA
gene id: 9940:CEBPA
uniprot id: W5VSV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

9940:ZNF706
gene id: 9940:ZNF706
uniprot id: W5QB53
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:ALG8
gene id: 9940:ALG8
uniprot id: W5P9G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:LOC101123333
gene id: 9940:LOC101123333
uniprot id: A0A836CVM4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AASDH
gene id: 9940:AASDH
uniprot id: W5P092
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9940:DYNLT3
gene id: 9940:DYNLT3
uniprot id: Q6XXL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis (By similarity).
messages: Belongs to the dynein light chain Tctex-type family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer. DYNLT1 and DYNLT3 compete for association with dynein IC (DYNC1I1 or DYNC1I2). Self-associates. Interacts with DYNC1I1 and DYNC1I2. Interacts with BUB3. Interacts with SATB1 in nucleus to form complex with matrix attachment regions (MARs) of DNA (By similarity).
messages: Nucleus
messages: cytoskeleton
messages: kinetochore

9940:SNRPA1
gene id: 9940:SNRPA1
uniprot id: B2LU27
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

9940:KRTAP4.3
gene id: 9940:KRTAP4.3
uniprot id: A8WEL6
names: Function
messages: The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).

9940:EXOSC7
gene id: 9940:EXOSC7
uniprot id: A0A6P3EEN9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MMP7
gene id: 9940:MMP7
uniprot id: B6UV58
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Binds 2 calcium ions per subunit.

9940:MELK
gene id: 9940:MELK
uniprot id: W5PPJ8
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9940:GPT2
gene id: 9940:GPT2
uniprot id: A0A6P3EFB3
uniprot id: W5Q2J9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANXA1
gene id: 9940:ANXA1
uniprot id: W5PSZ5
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

9940:STX8
gene id: 9940:STX8
uniprot id: A0A6P3YNV6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:QPCT
gene id: 9940:QPCT
uniprot id: C8BKD8
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

9940:PWWP3A
gene id: 9940:PWWP3A
uniprot id: W5PPK7
names: Similarity
messages: Belongs to the PWWP3A family.

9940:SELL
gene id: 9940:SELL
uniprot id: W5PMK6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selectin/LECAM family.
messages: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia.
messages: Cell membrane
messages: Interaction with SELPLG/PSGL1 and PODXL2 is required for promoting recruitment and rolling of leukocytes. This interaction is dependent on the sialyl Lewis X glycan modification of SELPLG and PODXL2, and tyrosine sulfation modifications of SELPLG. Sulfation on 'Tyr-51' of SELPLG is important for L-selectin binding.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:SAE1
gene id: 9940:SAE1
uniprot id: A0A6P3EFT0
uniprot id: W5PMQ9
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZPR1
gene id: 9940:ZPR1
uniprot id: A0A835ZRY6
names: Caution
names: Similarity
messages: Belongs to the ZPR1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123466
gene id: 9940:LOC101123466
uniprot id: A0A6P3YJD1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RERGL
gene id: 9940:RERGL
uniprot id: A0A6P3E3D0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MC5R
gene id: 9940:MC5R
uniprot id: A0A6P3CWQ3
uniprot id: Q19BK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GANAB
gene id: 9940:GANAB
uniprot id: W5Q302
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9940:COMMD3
gene id: 9940:COMMD3
uniprot id: A0A6P3EIJ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117015
gene id: 9940:LOC101117015
uniprot id: A0A6P3ECH0
uniprot id: W5PA59
names: Caution
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATG13
gene id: 9940:ATG13
uniprot id: A0A6P3ED78
uniprot id: W5P0V9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118932
gene id: 9940:LOC101118932
uniprot id: W5QHC6
names: Similarity
messages: Belongs to the AKAP110 family.

9940:TPST1
gene id: 9940:TPST1
uniprot id: W5PL91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9940:INTS7
gene id: 9940:INTS7
uniprot id: A0A6P3EEF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 7 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARF1
gene id: 9940:ARF1
uniprot id: A0A6P7E1T3
uniprot id: C5IWU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOXB1
gene id: 9940:HOXB1
uniprot id: A0A6P3EIP1
uniprot id: W5PB43
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family. Labial subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLIN2
gene id: 9940:PLIN2
uniprot id: A6ZE99
names: Similarity
messages: Belongs to the perilipin family.

9940:URI1
gene id: 9940:URI1
uniprot id: A0A6P3E9P7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114790
gene id: 9940:LOC101114790
uniprot id: A0A836D206
names: Caution
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCL1
gene id: 9940:CCL1
uniprot id: A0A6P3EJ98
uniprot id: W5PHD5
names: Caution
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLYATL2
gene id: 9940:GLYATL2
uniprot id: A0A6P3EGV7
uniprot id: W5PPP8
names: Caution
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113267
gene id: 9940:LOC101113267
uniprot id: A0A6P3EG12
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD82
gene id: 9940:CD82
uniprot id: W5NUN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:LOC101110319
gene id: 9940:LOC101110319
uniprot id: A0A836AKB9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABRA1
gene id: 9940:GABRA1
uniprot id: W5PWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:APLP2
gene id: 9940:APLP2
uniprot id: W5PZB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:LOC101117272
gene id: 9940:LOC101117272
uniprot id: W5NYL6
names: Similarity
messages: Belongs to the peptidase C14A family.

9940:SLC25A5
gene id: 9940:SLC25A5
uniprot id: A0A836CSN2
uniprot id: B2MVW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL12RB2
gene id: 9940:IL12RB2
uniprot id: G1JRQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

9940:DHRS9
gene id: 9940:DHRS9
uniprot id: A0A6P3E1C5
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPY4R2
gene id: 9940:NPY4R2
uniprot id: A0A6P3TAB6
uniprot id: W5P0I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPEB4
gene id: 9940:CPEB4
uniprot id: W5P288
names: Similarity
messages: Belongs to the RRM CPEB family.

9940:CWC15
gene id: 9940:CWC15
uniprot id: A0A6P3TBG1
names: Similarity
messages: Belongs to the CWC15 family.

9940:PAQR6
gene id: 9940:PAQR6
uniprot id: W5P6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9940:SLC25A3
gene id: 9940:SLC25A3
uniprot id: A0A6P3CXB5
uniprot id: B7U168
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FIP1L1
gene id: 9940:FIP1L1
uniprot id: A0A6P3YM81
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105036
gene id: 9940:LOC101105036
uniprot id: W5QFN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:YPEL1
gene id: 9940:YPEL1
uniprot id: A0A6P7D2H6
names: Similarity
messages: Belongs to the yippee family.

9940:ST7
gene id: 9940:ST7
uniprot id: Q09YI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9940:RHBDD2
gene id: 9940:RHBDD2
uniprot id: A0A6P3ELU6
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EFHB
gene id: 9940:EFHB
uniprot id: W5Q2A6
names: Subcellular Location Annotation
messages: cilium axoneme

9940:ZNF22
gene id: 9940:ZNF22
uniprot id: A0A6P3TK99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM199
gene id: 9940:TMEM199
uniprot id: A0A6P3EGY6
uniprot id: W5Q920
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103222
gene id: 9940:LOC101103222
uniprot id: W5QGU1
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9940:PCYOX1
gene id: 9940:PCYOX1
uniprot id: A0A836D3H7
names: Caution
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRM1
gene id: 9940:PRM1
uniprot id: A0A6P3CX03
uniprot id: C5IFA1
uniprot id: P68038
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the protamine P1 family.
messages: Chromosome
messages: Cross-linked by interchain disulfide bonds around the DNA-helix.
messages: Nucleus
messages: Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex.
messages: Testis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSTA
gene id: 9940:CSTA
uniprot id: W5QFV6
names: Similarity
messages: Belongs to the cystatin family.

9940:HOGA1
gene id: 9940:HOGA1
uniprot id: W5PMQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

9940:BEST3
gene id: 9940:BEST3
uniprot id: W5QGD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9940:SMIM29
gene id: 9940:SMIM29
uniprot id: A0A6P3EIZ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNS3
gene id: 9940:KCNS3
uniprot id: A0A6P3TIQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:GLUD1
gene id: 9940:GLUD1
uniprot id: A0A6P9FRG8
names: Caution
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RIC8B
gene id: 9940:RIC8B
uniprot id: A0A6P3EB05
uniprot id: W5Q8I2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HERC3
gene id: 9940:HERC3
uniprot id: A0A836D246
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF629
gene id: 9940:ZNF629
uniprot id: A0A6P3EQW5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117077
gene id: 9940:LOC101117077
uniprot id: W5PQF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CD40LG
gene id: 9940:CD40LG
uniprot id: Q4TVR2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

9940:CACNB1
gene id: 9940:CACNB1
uniprot id: W5PLJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

9940:RBBP9
gene id: 9940:RBBP9
uniprot id: A0A6P3EEQ6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJA4
gene id: 9940:DNAJA4
uniprot id: A0A836A0U4
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BICC1
gene id: 9940:BICC1
uniprot id: W5P1S7
names: Similarity
messages: Belongs to the BicC family.

9940:MEF2A
gene id: 9940:MEF2A
uniprot id: A0A6P3TD82
names: Subcellular Location Annotation
messages: Nucleus

9940:PIN1
gene id: 9940:PIN1
uniprot id: A0A6P3EDK0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCTS1
gene id: 9940:MCTS1
uniprot id: A0A6P3ESN3
uniprot id: W5PV64
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MFAP5
gene id: 9940:MFAP5
uniprot id: A0A6P3YL42
uniprot id: W5NV70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:LOC101114075
gene id: 9940:LOC101114075
uniprot id: A0A6P3ELP7
uniprot id: A0A6P3T5T9
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDS5A
gene id: 9940:PDS5A
uniprot id: A0A6P3YIC7
uniprot id: W5PRM6
names: Caution
names: Similarity
messages: Belongs to the PDS5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUB1
gene id: 9940:SUB1
uniprot id: A0A6P7DQI1
uniprot id: W5PRF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHODL
gene id: 9940:CHODL
uniprot id: A0A6P3E005
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SSTR5
gene id: 9940:SSTR5
uniprot id: Q8MI04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:C5H19orf25
gene id: 9940:C5H19orf25
uniprot id: W5PQU3
names: Similarity
messages: Belongs to the UPF0449 family.

9940:HSD11B2
gene id: 9940:HSD11B2
uniprot id: P50168
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the conversion of biologically active 11beta-hydroxyglucocorticoids (11beta-hydroxysteroid) such as cortisol, to inactive 11-ketoglucocorticoids (11-oxosteroid) such as cortisone, in the presence of NAD(+) (PubMed:7929304, PubMed:7588402). Functions as a dehydrogenase (oxidase), thereby decreasing the concentration of active glucocorticoids, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids (PubMed:7929304, PubMed:7588402). Plays an important role in maintaining glucocorticoids balance during preimplantation and protects the fetus from excessive maternal corticosterone exposure (By similarity). Catalyzes the oxidation of 11beta-hydroxytestosterone (11beta,17beta-dihydroxyandrost-4-ene-3-one) to 11-ketotestosterone (17beta-hydroxyandrost-4-ene-3,11-dione), a major bioactive androgen.Catalyzes the conversion of 11beta-hydroxyandrostenedione (11beta-hydroxyandrost-4-ene-3,17-dione) to 11-ketoandrostenedione (androst-4-ene-3,11,17-trione), which can be further metabolized to 11-ketotestosterone. Converts 7-beta-25-dihydroxycholesterol to 7-oxo-25-hydroxycholesterol in vitro. 7-beta-25-dihydroxycholesterol (not 7-oxo-25-hydroxycholesterol) acts as ligand for the G-protein-coupled receptor (GPCR) Epstein-Barr virus-induced gene 2 (EBI2) and may thereby regulate immune cell migration (By similarity). May protect ovulating oocytes and fertilizing spermatozoa from the adverse effects of cortisol (By similarity).
messages: Endoplasmic reticulum
messages: Highly expressed in the kidney and adrenal and at lower levels in the colon.
messages: Inhibited by glycyrrhetinic acid, carbenoloxone, 11-alpha-OH-progesterone and 11-beta-OH-progesterone.
messages: Interacts with ligand-free cytoplasmic NR3C2.
messages: Microsome

9940:CAND1
gene id: 9940:CAND1
uniprot id: W5NVQ4
names: Similarity
messages: Belongs to the CAND family.

9940:LDHAL6B
gene id: 9940:LDHAL6B
uniprot id: W5NXL6
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9940:GALNT5
gene id: 9940:GALNT5
uniprot id: A0A6P3E1R7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC51A
gene id: 9940:SLC51A
uniprot id: W5QGG9
names: Subcellular Location Annotation
messages: Membrane

9940:ATP5MC3
gene id: 9940:ATP5MC3
uniprot id: W5NPR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

9940:TUBGCP5
gene id: 9940:TUBGCP5
uniprot id: W5Q2M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9940:LOC101121060
gene id: 9940:LOC101121060
uniprot id: W5PBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TMC3
gene id: 9940:TMC3
uniprot id: W5Q2S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9940:MLH1
gene id: 9940:MLH1
uniprot id: W5Q4Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

9940:ALB
gene id: 9940:ALB
uniprot id: P14639
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the ALB/AFP/VDB family.
messages: Binds water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (By similarity). The shared binding site between zinc and calcium at residue Asp-272 suggests a crosstalk between zinc and calcium transport in the blood (By similarity). The rank order of affinity is zinc > calcium > magnesium (By similarity). Binds to the bacterial siderophore enterobactin and inhibits enterobactin-mediated iron uptake of E.coli from ferric transferrin, and may thereby limit the utilization of iron and growth of enteric bacteria such as E.coli (By similarity). Does not prevent iron uptake by the bacterial siderophore aerobactin (By similarity).
messages: Interacts with FCGRT; this interaction regulates ALB homeostasis (By similarity). Interacts with TASOR (By similarity). In plasma, occurs in a covalently-linked complex with chromophore-bound alpha-1-microglobulin; this interaction does not prevent fatty acid binding to ALB.
messages: Phosphorylated by FAM20C in the extracellular medium.
messages: Plasma.
messages: Secreted

9940:LOC101106041
gene id: 9940:LOC101106041
uniprot id: A0A835ZWN2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS27
gene id: 9940:RPS27
uniprot id: A0A836AQY8
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNG1
gene id: 9940:KCNG1
uniprot id: W5PXL3
names: Subcellular Location Annotation
messages: Membrane

9940:TGM3
gene id: 9940:TGM3
uniprot id: W5PB04
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9940:APOA2
gene id: 9940:APOA2
uniprot id: A0A6P3E7G9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein A2 family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SKP1
gene id: 9940:SKP1
uniprot id: A0A6P9FQJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

9940:ALAS2
gene id: 9940:ALAS2
uniprot id: A0A6P3EH69
uniprot id: W5P6N1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS3A
gene id: 9940:RPS3A
uniprot id: W5P6A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.
messages: Cytoplasm
messages: May play a role during erythropoiesis through regulation of transcription factor DDIT3.
messages: Nucleus

9940:COLGALT2
gene id: 9940:COLGALT2
uniprot id: A0A836A924
uniprot id: W5NWK3
names: Caution
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPR85
gene id: 9940:GPR85
uniprot id: A0A6P3E8V5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RALY
gene id: 9940:RALY
uniprot id: A0A6P3TJT0
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9940:LOC101116514
gene id: 9940:LOC101116514
uniprot id: A0A6P3ECT7
uniprot id: W5PGR2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105185
gene id: 9940:LOC101105185
uniprot id: W5QCV3
names: Similarity
messages: Belongs to the globin family.

9940:GPX8
gene id: 9940:GPX8
uniprot id: W5PDN4
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9940:HAPLN1
gene id: 9940:HAPLN1
uniprot id: A0A6P3ED94
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:SLC5A7
gene id: 9940:SLC5A7
uniprot id: A0A6P3EAY5
uniprot id: W5QIH8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LDB1
gene id: 9940:LDB1
uniprot id: A0A6P3EDN4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB4B
gene id: 9940:RAB4B
uniprot id: A0A6P3ECE4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NAGA
gene id: 9940:NAGA
uniprot id: A0A6P3CWU6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9940:HSP90AB1
gene id: 9940:HSP90AB1
uniprot id: W5PHW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

9940:P2RX5
gene id: 9940:P2RX5
uniprot id: W5Q7S4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9940:HOXD10
gene id: 9940:HOXD10
uniprot id: W5Q7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9940:DHPS
gene id: 9940:DHPS
uniprot id: A0A6P3EDJ4
uniprot id: W5PR99
names: Caution
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UFL1
gene id: 9940:UFL1
uniprot id: A0A836A4A7
names: Caution
names: Similarity
messages: Belongs to the UFL1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMA6
gene id: 9940:PSMA6
uniprot id: B6EBS6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9940:MIXL1
gene id: 9940:MIXL1
uniprot id: W5NPE5
names: Subcellular Location Annotation
messages: Nucleus

9940:BET1L
gene id: 9940:BET1L
uniprot id: A0A6P3EFK9
uniprot id: W5PGY2
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS37A
gene id: 9940:VPS37A
uniprot id: W5PI05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

9940:XPNPEP1
gene id: 9940:XPNPEP1
uniprot id: W5PGW8
names: Similarity
messages: Belongs to the peptidase M24B family.

9940:MTX3
gene id: 9940:MTX3
uniprot id: W5Q7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9940:TMED3
gene id: 9940:TMED3
uniprot id: A0A6P3EMM0
uniprot id: W5Q045
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network membrane

9940:PPP4R3A
gene id: 9940:PPP4R3A
uniprot id: A0A6P3EBY4
uniprot id: W5PR01
names: Caution
names: Similarity
messages: Belongs to the SMEK family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PYGL
gene id: 9940:PYGL
uniprot id: Q5MIB5
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation, which is up-regulated by glucose and insulin and down-regulated by glucagon, inhibits the glycogen phosphorylase activity by promoting PPP1R3B-mediated recruitment of phosphatase PP1 and Ser-15 dephosphorylation.
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Allosterically regulated through the non-covalent binding of metabolites, being activated by AMP and inhibited by ATP, ADP, and glucose-6-phosphate. The activity is also controlled by post-translational modifications including phosphorylation and acetylation.
messages: Belongs to the glycogen phosphorylase family.
messages: Homodimer; enzymatically active. Interacts with PPP1R3B; recruits the phosphatase PP1 which dephosphorylates and inactivates PYGL/glycogen phosphorylase.
messages: Phosphorylation at Ser-15 converts inactive phosphorylase b into active phosphorylase a. Dephosphorylation of Ser-15 by phosphatase PP1 inactivates the enzyme.
messages: cytosol

9940:PAEP
gene id: 9940:PAEP
uniprot id: P67976
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Alternate disulfide bonds occur in equal amounts.
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule.
messages: Secreted
messages: Under physiological conditions beta-lactoglobulin exists as an equilibrium mixture of monomeric and dimeric forms.

9940:DGAT2L6
gene id: 9940:DGAT2L6
uniprot id: A0A6P3EF30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRPR
gene id: 9940:GRPR
uniprot id: A0A6P3EEU2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CISD3
gene id: 9940:CISD3
uniprot id: A0A6P3EDE0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP15
gene id: 9940:USP15
uniprot id: A0A6P3E7T5
uniprot id: W5P393
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE2G2
gene id: 9940:UBE2G2
uniprot id: A0A6P3YIW7
uniprot id: W5PRP9
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRPC1
gene id: 9940:TRPC1
uniprot id: A0A6P3E007
uniprot id: W5P7M3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Seems to be also activated by intracellular calcium store depletion.

9940:CAPZA3
gene id: 9940:CAPZA3
uniprot id: A0A6P3EB64
uniprot id: W5QG90
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113004
gene id: 9940:LOC101113004
uniprot id: W5PMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9940:LOC101120955
gene id: 9940:LOC101120955
uniprot id: A0A6P3EP38
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAPPC2
gene id: 9940:TRAPPC2
uniprot id: W5PP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

9940:XYLT2
gene id: 9940:XYLT2
uniprot id: W5P3L6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

9940:GINS4
gene id: 9940:GINS4
uniprot id: A0A6P3YPY0
uniprot id: W5NWH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HACD1
gene id: 9940:HACD1
uniprot id: Q9N1R5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Expressed in heart.
messages: May interact with enzymes of the ELO family (including ELOVL1); with those enzymes that mediate condensation, the first of the four steps of the reaction cycle responsible for fatty acids elongation, may be part of a larger fatty acids elongase complex.
messages: N-glycosylated.
messages: Shares some similarity with tyrosine phosphatase proteins but it has probably no phosphatase activity.

9940:MGAT1
gene id: 9940:MGAT1
uniprot id: W5Q5G1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans.
messages: Membrane
messages: The cofactor is mostly bound to the substrate.

9940:ODF2L
gene id: 9940:ODF2L
uniprot id: A0A836AP48
uniprot id: W5PYS3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome

9940:DBR1
gene id: 9940:DBR1
uniprot id: W5PCI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

9940:SOX14
gene id: 9940:SOX14
uniprot id: W5Q1Z3
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101106767
gene id: 9940:LOC101106767
uniprot id: A0A6P3TFZ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIN52
gene id: 9940:LIN52
uniprot id: W5NS60
names: Similarity
messages: Belongs to the lin-52 family.

9940:NNT
gene id: 9940:NNT
uniprot id: A0A571N6A6
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9940:AKAP4
gene id: 9940:AKAP4
uniprot id: A0A6P3TAY9
uniprot id: W5PJZ7
names: Caution
names: Similarity
messages: Belongs to the AKAP110 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3H
gene id: 9940:POLR3H
uniprot id: W5QAB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

9940:MMP20
gene id: 9940:MMP20
uniprot id: W5P7K9
names: Similarity
messages: Belongs to the peptidase M10A family.

9940:COG4
gene id: 9940:COG4
uniprot id: W5P4D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG4 family.
messages: Golgi apparatus membrane

9940:GAS8
gene id: 9940:GAS8
uniprot id: W5Q110
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC4 family.
messages: flagellum axoneme

9940:RNF14
gene id: 9940:RNF14
uniprot id: A0A6P3TE22
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107469
gene id: 9940:LOC101107469
uniprot id: W5PC45
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:C7H15orf61
gene id: 9940:C7H15orf61
uniprot id: A0A6P3EEI7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLA2G4B
gene id: 9940:PLA2G4B
uniprot id: W5QGU7
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9940:MDK
gene id: 9940:MDK
uniprot id: W5P004
names: Similarity
messages: Belongs to the pleiotrophin family.

9940:RAB4A
gene id: 9940:RAB4A
uniprot id: A0A6P3CXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

9940:POLR2C
gene id: 9940:POLR2C
uniprot id: A0A6P3EL09
uniprot id: W5NQ60
names: Caution
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDE6G
gene id: 9940:PDE6G
uniprot id: A0A6P3EDT0
names: Caution
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109838
gene id: 9940:LOC101109838
uniprot id: A0A836AFM0
uniprot id: W5PWL0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
messages: Peroxisome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103181
gene id: 9940:LOC101103181
uniprot id: A0A836A0T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF821
gene id: 9940:ZNF821
uniprot id: A0A6P3TKB7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAR
gene id: 9940:STAR
uniprot id: A0A835ZN77
uniprot id: P79245
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity).
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM11
gene id: 9940:TMEM11
uniprot id: A0A6P3EA54
uniprot id: W5NWY1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BRIX1
gene id: 9940:BRIX1
uniprot id: A0A6P3ENF2
uniprot id: W5PPJ4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:PSPH
gene id: 9940:PSPH
uniprot id: B2LU26
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

9940:RFK
gene id: 9940:RFK
uniprot id: A0A6P3YHL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL35A
gene id: 9940:RPL35A
uniprot id: A0A836AQ54
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP1R11
gene id: 9940:PPP1R11
uniprot id: A0A6P3EQ18
uniprot id: W5Q4B9
names: Caution
names: Subunit
messages: Interacts with TLR2 and UBE2D2.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120103
gene id: 9940:LOC101120103
uniprot id: A0A835ZTV1
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DLX3
gene id: 9940:DLX3
uniprot id: C0L2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

9940:PIK3C3
gene id: 9940:PIK3C3
uniprot id: A0A6P3ER65
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC26A3
gene id: 9940:SLC26A3
uniprot id: D6QUQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Chloride/bicarbonate exchanger.
messages: Membrane

9940:C25H10orf53
gene id: 9940:C25H10orf53
uniprot id: W5NVQ3
names: Similarity
messages: Belongs to the UPF0728 family.

9940:STRADA
gene id: 9940:STRADA
uniprot id: A0A6P3CXH8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DIO3
gene id: 9940:DIO3
uniprot id: Q6DN07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iodothyronine deiodinase family.
messages: Cell membrane
messages: Endosome membrane
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.

9940:TLR4
gene id: 9940:TLR4
uniprot id: B5DC89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9940:NRF1
gene id: 9940:NRF1
uniprot id: A0A6P3TG79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

9940:PDAP1
gene id: 9940:PDAP1
uniprot id: A0A6P3YPH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAK1
gene id: 9940:PAK1
uniprot id: A0A6P3EJX5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103947
gene id: 9940:LOC101103947
uniprot id: W5P7S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Functions as transport protein in the blood stream.
messages: Secreted

9940:C9H8orf76
gene id: 9940:C9H8orf76
uniprot id: A0A6P3EG82
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EBPL
gene id: 9940:EBPL
uniprot id: W5PFJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:LOC101108931
gene id: 9940:LOC101108931
uniprot id: A0A6P3EHQ7
uniprot id: W5Q8W8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:APPBP2
gene id: 9940:APPBP2
uniprot id: A0A6P3E9M7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LANCL1
gene id: 9940:LANCL1
uniprot id: W5QD23
names: Similarity
messages: Belongs to the LanC-like protein family.

9940:CYP17
gene id: 9940:CYP17
uniprot id: W5NVQ8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:POU2F3
gene id: 9940:POU2F3
uniprot id: A0A6P3YQF2
uniprot id: J7IHV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BCO2
gene id: 9940:BCO2
uniprot id: W5Q4D5
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9940:STARD3NL
gene id: 9940:STARD3NL
uniprot id: A0A6P3TR98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9940:ATP6V0B
gene id: 9940:ATP6V0B
uniprot id: A0A6P3E676
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

9940:PLAGL2
gene id: 9940:PLAGL2
uniprot id: A0A835ZU85
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CACNA1D
gene id: 9940:CACNA1D
uniprot id: W5Q3W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

9940:SLC17A5
gene id: 9940:SLC17A5
uniprot id: Q9MZD1
uniprot id: W5P894
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
messages: Lysosome membrane
messages: Membrane
messages: Primary solute translocator for anionic substances; particularly it is a free sialic acid transporter in the lysosomes (Probable). Receptor for CM101, a polysaccharide produced by group B Streptococcus with antipathoangiogenic properties.
messages: Significantly expressed in lung endothelial cells, and much less in liver.

9940:PSMB10
gene id: 9940:PSMB10
uniprot id: A0A6P3EL31
uniprot id: W5NZ57
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CETN2
gene id: 9940:CETN2
uniprot id: A0A6P9FQM8
names: Similarity
messages: Belongs to the centrin family.

9940:PYCR1
gene id: 9940:PYCR1
uniprot id: A0A6P3YNX0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9940:UTP6
gene id: 9940:UTP6
uniprot id: W5PVG8
names: Similarity
messages: Belongs to the UTP6 family.

9940:ATP5PD
gene id: 9940:ATP5PD
uniprot id: B7P027
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9940:PDE6D
gene id: 9940:PDE6D
uniprot id: A0A6P3EA65
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PDE6D/unc-119 family.
messages: Cytoplasmic vesicle membrane
messages: Interacts with the prenylated catalytic subunits of PDE6, an oligomer composed of two catalytic chains and two inhibitory chains; has no effect on enzyme activity but promotes the release of the prenylated enzyme from cell membrane.
messages: Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium basal body
messages: cytosol

9940:PUS1
gene id: 9940:PUS1
uniprot id: A0A6P9FQP1
uniprot id: W5PUZ2
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

9940:LOC101118999
gene id: 9940:LOC101118999
uniprot id: A0A6P3ENY7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARMC8
gene id: 9940:ARMC8
uniprot id: A0A6P3YJD4
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM167A
gene id: 9940:FAM167A
uniprot id: A0A836D910
names: Caution
names: Similarity
messages: Belongs to the FAM167 (SEC) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRNA6
gene id: 9940:CHRNA6
uniprot id: W5NZZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:EFTUD2
gene id: 9940:EFTUD2
uniprot id: A0A6P3EDN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBXN10
gene id: 9940:UBXN10
uniprot id: A0A836D775
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRMT7
gene id: 9940:PRMT7
uniprot id: A0A6P3EL40
uniprot id: A0A6P7ERX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:TMEM169
gene id: 9940:TMEM169
uniprot id: A0A836AN88
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMSB15B
gene id: 9940:TMSB15B
uniprot id: W5NQY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9940:LOC101105324
gene id: 9940:LOC101105324
uniprot id: A0A6P3E498
uniprot id: A0A6P7E0Q2
names: Caution
names: Similarity
messages: Belongs to the Luc7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARMC1
gene id: 9940:ARMC1
uniprot id: W5Q6F2
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In association with mitochondrial contact site and cristae organizing system (MICOS) complex components and mitochondrial outer membrane sorting assembly machinery (SAM) complex components may regulate mitochondrial dynamics playing a role in determining mitochondrial length, distribution and motility.
messages: Membrane
messages: Mitochondrion outer membrane

9940:CCDC32
gene id: 9940:CCDC32
uniprot id: A0A836D1H0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC46A3
gene id: 9940:SLC46A3
uniprot id: W5PR93
names: Subcellular Location Annotation
messages: Membrane

9940:DNAJC16
gene id: 9940:DNAJC16
uniprot id: A0A6P3E8S3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANKRD49
gene id: 9940:ANKRD49
uniprot id: A0A6P3EK24
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLYCAM1
gene id: 9940:GLYCAM1
uniprot id: W5Q3I2
names: Similarity
messages: Belongs to the PP3/GlyCAM-1 family.

9940:GLS2
gene id: 9940:GLS2
uniprot id: A0A836D574
uniprot id: W5PFS4
names: Caution
names: Similarity
messages: Belongs to the glutaminase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DYNC2H1
gene id: 9940:DYNC2H1
uniprot id: W5P0H6
names: Similarity
messages: Belongs to the dynein heavy chain family.

9940:LOC101102548
gene id: 9940:LOC101102548
uniprot id: W5Q4K3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9940:ATP8B4
gene id: 9940:ATP8B4
uniprot id: W5QIL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9940:MAP3K7
gene id: 9940:MAP3K7
uniprot id: W5PRX8
uniprot id: W5PRX9
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by pro-inflammatory cytokines and in response to physical and chemical stresses, including osmotic stress, oxidative stress, arsenic and ultraviolet light irradiation. Activated by 'Lys-63'-linked polyubiquitination and by autophosphorylation.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm

9940:TOMT
gene id: 9940:TOMT
uniprot id: A0A6P9FRH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108696
gene id: 9940:LOC101108696
uniprot id: A8IW63
names: Similarity
messages: Belongs to the MHC class II family.

9940:METTL14
gene id: 9940:METTL14
uniprot id: A0A6P3E6K8
uniprot id: W5Q720
names: Caution
names: Similarity
messages: Belongs to the MT-A70-like family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC12A4
gene id: 9940:SLC12A4
uniprot id: Q7YS96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9940:FGF2
gene id: 9940:FGF2
uniprot id: P20003
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4 (By similarity). Also acts as an integrin ligand which is required for FGF2 signaling (By similarity). Binds to integrin ITGAV:ITGB3 (By similarity). Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration (By similarity). Functions as a potent mitogen in vitro (By similarity). Can induce angiogenesis (By similarity). Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation (By similarity).
messages: Belongs to the heparin-binding growth factors family.
messages: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Interacts with CSPG4, FGFBP1 and TEC. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP3. Interacts with integrin ITGAV:ITGB3; the interaction is required for FGF2 signaling. Interacts with SNORC (via the extracellular domain). Interacts with glypican GPC3 (By similarity).
messages: Nucleus
messages: Phosphorylation at Tyr-82 regulates FGF2 unconventional secretion.
messages: Secreted

9940:RIC3
gene id: 9940:RIC3
uniprot id: W5Q087
names: Similarity
messages: Belongs to the ric-3 family.

9940:LCTL
gene id: 9940:LCTL
uniprot id: A0A835ZZU4
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DPAGT1
gene id: 9940:DPAGT1
uniprot id: A0A835ZR68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM199X
gene id: 9940:FAM199X
uniprot id: W5NR24
names: Similarity
messages: Belongs to the FAM199 family.

9940:NOL9
gene id: 9940:NOL9
uniprot id: A0A6P3E8R1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC114108604
gene id: 9940:LOC114108604
uniprot id: A4ZVY9
uniprot id: Q6QAT4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta-2-microglobulin family.
messages: Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity).
messages: Heterodimer of an alpha chain and a beta chain. Beta-2-microglobulin is the beta-chain of major histocompatibility complex class I molecules (By similarity).
messages: Secreted

9940:POLR1C
gene id: 9940:POLR1C
uniprot id: A0A6P3EJ63
uniprot id: A0A6P3TEI3
names: Caution
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFAIP6
gene id: 9940:TNFAIP6
uniprot id: W5PGW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:GZMM
gene id: 9940:GZMM
uniprot id: A0A6P3YLU6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MMADHC
gene id: 9940:MMADHC
uniprot id: A0A836D6Q0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KIAA1191
gene id: 9940:KIAA1191
uniprot id: W5Q4V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P33MONOX family.
messages: Cytoplasm
messages: Interacts with NELFB, NOL12 and PRNP.
messages: Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth.

9940:MTREX
gene id: 9940:MTREX
uniprot id: A0A6P3EB49
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HDDC3
gene id: 9940:HDDC3
uniprot id: A0A6P3ENX1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RALB
gene id: 9940:RALB
uniprot id: A0A6P7DQB7
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

9940:INTS3
gene id: 9940:INTS3
uniprot id: A0A6P3E603
uniprot id: W5NSM6
names: Caution
names: Similarity
messages: Belongs to the Integrator subunit 3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHP1
gene id: 9940:CHP1
uniprot id: A0A6P3EAY4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PARP11
gene id: 9940:PARP11
uniprot id: W5PKZ8
names: Similarity
messages: Belongs to the ARTD/PARP family.

9940:PGM5
gene id: 9940:PGM5
uniprot id: A0A6P3E5Z2
uniprot id: W5PUA9
names: Caution
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SKAP2
gene id: 9940:SKAP2
uniprot id: A0A6P3YHL0
uniprot id: W5PJQ2
names: Caution
names: Similarity
messages: Belongs to the SKAP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRK7
gene id: 9940:GRK7
uniprot id: W5P987
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9940:HYOU1
gene id: 9940:HYOU1
uniprot id: A0A6P3TBL3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9940:KEF53 p12
gene id: 9940:KEF53_p12
uniprot id: O78748
uniprot id: Q5MA76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM242 (By similarity).
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits. Interacts with TMEM242.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9940:UBQLN2
gene id: 9940:UBQLN2
uniprot id: W5P682
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: autophagosome

9940:ACP1
gene id: 9940:ACP1
uniprot id: W5P582
uniprot id: W5P583
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

9940:LOC101116302
gene id: 9940:LOC101116302
uniprot id: A0A836A542
uniprot id: W5P2W9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1H21orf62
gene id: 9940:C1H21orf62
uniprot id: A0A6P3DZY0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108797
gene id: 9940:LOC101108797
uniprot id: A0A6P7DGJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

9940:HCK
gene id: 9940:HCK
uniprot id: W5NXU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9940:RPSA
gene id: 9940:RPSA
uniprot id: A6YRY8
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acylated. Acylation may be a prerequisite for conversion of the monomeric 37 kDa laminin receptor precursor (37LRP) to the mature dimeric 67 kDa laminin receptor (67LR), and may provide a mechanism for membrane association.
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Cell membrane
messages: Cleaved by stromelysin-3 (ST3) at the cell surface. Cleavage by stromelysin-3 may be a mechanism to alter cell-extracellular matrix interactions.
messages: Cytoplasm
messages: It is thought that in vertebrates 37/67 kDa laminin receptor acquired a dual function during evolution. It developed from the ribosomal protein SA, playing an essential role in the protein biosynthesis lacking any laminin binding activity, to a cell surface receptor with laminin binding activity.
messages: Monomer (37LRP) and homodimer (67LR). Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Interacts with RPS21. Interacts with several laminins including at least LAMB1. Interacts with MDK. The mature dimeric form interacts with PPP1R16B (via its fourth ankyrin repeat). Interacts with PPP1CA only in the presence of PPP1R16B.
messages: Nucleus
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.
messages: This protein appears to have acquired a second function as a laminin receptor specifically in the vertebrate lineage.

9940:ORAI2
gene id: 9940:ORAI2
uniprot id: A0A6P3T5Y4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TEX261
gene id: 9940:TEX261
uniprot id: A0A6P3YGW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

9940:CBLN1
gene id: 9940:CBLN1
uniprot id: A0A6P3E9J7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC5A12
gene id: 9940:SLC5A12
uniprot id: W5PYF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9940:PAN2
gene id: 9940:PAN2
uniprot id: A0A6P3EAS8
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TUBAL3
gene id: 9940:TUBAL3
uniprot id: W5PH73
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9940:HBEGF
gene id: 9940:HBEGF
uniprot id: A0A6P3E9M8
uniprot id: W5Q7W2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANGPTL4
gene id: 9940:ANGPTL4
uniprot id: W6AX51
names: Subcellular Location Annotation
messages: Secreted

9940:POLD4
gene id: 9940:POLD4
uniprot id: A0A6P3EK96
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ROPN1L
gene id: 9940:ROPN1L
uniprot id: A0A6P3EHK2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM127
gene id: 9940:TMEM127
uniprot id: A0A836ACL3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OCEL1
gene id: 9940:OCEL1
uniprot id: W5Q8H5
names: Similarity
messages: Belongs to the ELL/occludin family.

9940:RWDD4
gene id: 9940:RWDD4
uniprot id: A0A6P3EEP3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPR61
gene id: 9940:GPR61
uniprot id: A0A836D9S7
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DUOX2
gene id: 9940:DUOX2
uniprot id: D7REY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
messages: In the N-terminal section; belongs to the peroxidase family.
messages: Membrane

9940:NOL11
gene id: 9940:NOL11
uniprot id: W5Q2J3
names: Subcellular Location Annotation
messages: nucleolus

9940:TNFSF8
gene id: 9940:TNFSF8
uniprot id: A0A6P3E0U5
uniprot id: W5P7H7
names: Caution
names: Similarity
messages: Belongs to the tumor necrosis factor family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIMREG
gene id: 9940:PIMREG
uniprot id: A0A6P3ED15
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLRG1
gene id: 9940:PLRG1
uniprot id: A0A6P3TG74
uniprot id: W5NRL3
names: Caution
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYP2E1
gene id: 9940:CYP2E1
uniprot id: A0A6P9FQP0
uniprot id: F1CGV3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110434
gene id: 9940:LOC101110434
uniprot id: W5PSE5
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:SLPI
gene id: 9940:SLPI
uniprot id: Q6V9X0
names: Function
names: Induction
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Acid-stable proteinase inhibitor with strong affinities for trypsin, chymotrypsin, elastase, and cathepsin G. Modulates the inflammatory and immune responses after bacterial infection, and after infection by the intracellular parasite L.major. Down-regulates responses to bacterial lipopolysaccharide (LPS). Plays a role in regulating the activation of NF-kappa-B and inflammatory responses. Has antimicrobial activity against mycobacteria, but not against salmonella. Contributes to normal resistance against infection by M.tuberculosis. Required for normal resistance to infection by L.major. Required for normal wound healing, probably by preventing tissue damage by limiting protease activity (By similarity). Together with ELANE, required for normal differentiation and proliferation of bone marrow myeloid cells (By similarity).
messages: Detected in bronchoalveolar fluid (at protein level). Detected in large and small intestine, trachea, skin, lung and tongue.
messages: Interacts with GRN; interaction protects progranulin from proteolysis.
messages: Secreted
messages: Up-regulated in response to bacterial lipopolysaccharide (LPS) in bronchoalveolar fluid (at protein level).

9940:LOC101103208
gene id: 9940:LOC101103208
uniprot id: A0A836CQK8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: clathrin-coated vesicle
messages: trans-Golgi network

9940:CDH9
gene id: 9940:CDH9
uniprot id: W5PT37
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9940:PTER
gene id: 9940:PTER
uniprot id: A0A836A776
uniprot id: W5PGQ7
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107135
gene id: 9940:LOC101107135
uniprot id: A0A6P3EH31
uniprot id: W5PQR4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBXO25
gene id: 9940:FBXO25
uniprot id: A0A6P7DER7
uniprot id: W5PVK5
names: Subcellular Location Annotation
messages: Nucleus

9940:LMOD3
gene id: 9940:LMOD3
uniprot id: A0A6P3T313
uniprot id: A0A6P3TBJ2
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton
messages: sarcomere

9940:LOC101110649
gene id: 9940:LOC101110649
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117005
gene id: 9940:LOC101117005
uniprot id: A0A6P3EE27
uniprot id: W5P514
names: Caution
names: Similarity
messages: Belongs to the COX20 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDI2
gene id: 9940:GDI2
uniprot id: A0A6P9FQJ0
uniprot id: C5IJ88
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106658
gene id: 9940:LOC101106658
uniprot id: A0A6P7DM26
uniprot id: V9GZC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZDHHC6
gene id: 9940:ZDHHC6
uniprot id: A0A6P3EQ63
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RND3
gene id: 9940:RND3
uniprot id: A0A6P3E1S8
uniprot id: W5PHI3
names: Caution
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:G2E3
gene id: 9940:G2E3
uniprot id: A0A6P3T6R2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TLR5
gene id: 9940:TLR5
uniprot id: B5DC90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9940:LOC101122977
gene id: 9940:LOC101122977
uniprot id: W5PBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:NAIF1
gene id: 9940:NAIF1
uniprot id: A0A6P3E2D1
uniprot id: W5PMT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC126
gene id: 9940:CCDC126
uniprot id: A0A6P3E4L1
uniprot id: A0A6P3TMQ1
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPBWR2
gene id: 9940:NPBWR2
uniprot id: A0A6P3EIT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120489
gene id: 9940:LOC101120489
uniprot id: A0A6P3EA32
uniprot id: W5NTE7
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARHGDIB
gene id: 9940:ARHGDIB
uniprot id: W5QHP6
names: Similarity
messages: Belongs to the Rho GDI family.

9940:LEF1
gene id: 9940:LEF1
uniprot id: W5PDZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

9940:TSSK4
gene id: 9940:TSSK4
uniprot id: A0A6P3TFE7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIPH
gene id: 9940:LIPH
uniprot id: A0A6P3E816
uniprot id: W5QH96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PEX5L
gene id: 9940:PEX5L
uniprot id: A0A836AFH3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CATHL1B
gene id: 9940:CATHL1B
uniprot id: A0A6P7D5A0
uniprot id: P54230
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Potent microbicidal activity; active against S.aureus and E.coli.
messages: Secreted

9940:GBA
gene id: 9940:GBA
uniprot id: W5P1A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 30 family.
messages: Lysosome membrane

9940:TUBB1
gene id: 9940:TUBB1
uniprot id: W5Q3I7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9940:DDIT4
gene id: 9940:DDIT4
uniprot id: A0A6P3EGR1
uniprot id: W5PB57
names: Caution
names: Similarity
messages: Belongs to the DDIT4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMCO1
gene id: 9940:TMCO1
uniprot id: W5PPH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer and homotetramer. Homodimer under resting conditions; forms homotetramers following and ER calcium overload.
messages: Membrane

9940:FAM219B
gene id: 9940:FAM219B
uniprot id: W5NY39
names: Similarity
messages: Belongs to the FAM219 family.

9940:MRPL32
gene id: 9940:MRPL32
uniprot id: W5Q7B1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

9940:GHRL
gene id: 9940:GHRL
uniprot id: Q863L0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

9940:CHMP2A
gene id: 9940:CHMP2A
uniprot id: A0A6P3EA09
uniprot id: A0A6P3EFY0
names: Caution
names: Similarity
messages: Belongs to the SNF7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MKLN1
gene id: 9940:MKLN1
uniprot id: A0A6P3E573
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSTF2
gene id: 9940:CSTF2
uniprot id: W5NSC2
names: Subcellular Location Annotation
messages: Nucleus

9940:CCDC22
gene id: 9940:CCDC22
uniprot id: W5PL73
names: Similarity
messages: Belongs to the CCDC22 family.

9940:PPOX
gene id: 9940:PPOX
uniprot id: W5PIT5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

9940:FABP12
gene id: 9940:FABP12
uniprot id: W5PI01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9940:PLN
gene id: 9940:PLN
uniprot id: W5QFE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholamban family.
messages: Endoplasmic reticulum membrane
messages: Homopentamer.
messages: Membrane
messages: Mitochondrion membrane
messages: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.
messages: Sarcoplasmic reticulum membrane

9940:ACTR1A
gene id: 9940:ACTR1A
uniprot id: A0A6P3EFT3
uniprot id: W5NSM1
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPI
gene id: 9940:GPI
uniprot id: W5P323
names: Similarity
messages: Belongs to the GPI family.

9940:RBPJ
gene id: 9940:RBPJ
uniprot id: A0A6P3TN17
uniprot id: U5PR56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYL1
gene id: 9940:MYL1
uniprot id: A0A6P3EA17
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MS4A13
gene id: 9940:MS4A13
uniprot id: W5PUE2
names: Similarity
messages: Belongs to the MS4A family.

9940:RSPO2
gene id: 9940:RSPO2
uniprot id: A0A6P3YN12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

9940:EIF4A3
gene id: 9940:EIF4A3
uniprot id: W5NVU4
names: Similarity
messages: Belongs to the DEAD box helicase family.

9940:LSM12
gene id: 9940:LSM12
uniprot id: A0A6P3EAH2
names: Caution
names: Similarity
messages: Belongs to the LSM12 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DRAP1
gene id: 9940:DRAP1
uniprot id: A0A6P3EQN1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TP53BP2
gene id: 9940:TP53BP2
uniprot id: A0A6P3EE12
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP2R1B
gene id: 9940:PPP2R1B
uniprot id: A0A6P3EK56
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105868
gene id: 9940:LOC101105868
uniprot id: A0A6P3DZI2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIPA
gene id: 9940:LIPA
uniprot id: B2LSM5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9940:CSTF3
gene id: 9940:CSTF3
uniprot id: A0A6P3EAK2
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TLR2
gene id: 9940:TLR2
uniprot id: Q09I12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides.
messages: Membrane
messages: Membrane raft
messages: phagosome membrane

9940:COPS8
gene id: 9940:COPS8
uniprot id: A0A6P3TGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

9940:C22H10orf90
gene id: 9940:C22H10orf90
uniprot id: W5PSX1
names: Subcellular Location Annotation
messages: centrosome

9940:LRRFIP1
gene id: 9940:LRRFIP1
uniprot id: W5QCH0
names: Similarity
messages: Belongs to the LRRFIP family.

9940:IKZF5
gene id: 9940:IKZF5
uniprot id: A0A6P3EKY3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRLN
gene id: 9940:MRLN
uniprot id: A0A6P9FRI4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC41A2
gene id: 9940:SLC41A2
uniprot id: A0A6P3E825
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9940:TEKT3
gene id: 9940:TEKT3
uniprot id: W5Q4X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9940:ING1
gene id: 9940:ING1
uniprot id: W5PAR4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9940:LOC101102344
gene id: 9940:LOC101102344
uniprot id: A0A835ZVV9
uniprot id: W5QFN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HOXC9
gene id: 9940:HOXC9
uniprot id: A0A6P3EBG6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLK3
gene id: 9940:CLK3
uniprot id: A0A6P3EBV4
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NBN
gene id: 9940:NBN
uniprot id: A0A836AB93
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: telomere

9940:PPIL1
gene id: 9940:PPIL1
uniprot id: A0A6P3ENI7
names: Caution
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HRH4
gene id: 9940:HRH4
uniprot id: W5PBL0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:MTFR1L
gene id: 9940:MTFR1L
uniprot id: A0A6P3T9T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107433
gene id: 9940:LOC101107433
uniprot id: W5Q9J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:NAP1L4
gene id: 9940:NAP1L4
uniprot id: A0A835ZN33
names: Caution
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFT22
gene id: 9940:IFT22
uniprot id: A0A6P3ELV4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFA10
gene id: 9940:NDUFA10
uniprot id: A0A8N7XJK5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANGPTL5
gene id: 9940:ANGPTL5
uniprot id: A0A6P3EK39
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB7B
gene id: 9940:RAB7B
uniprot id: A0A6P3EDY6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TM4SF4
gene id: 9940:TM4SF4
uniprot id: A0A6P3DZZ4
uniprot id: W5P442
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SESN3
gene id: 9940:SESN3
uniprot id: A0A6P3YLX1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLG1
gene id: 9940:GLG1
uniprot id: W5P6V4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

9940:SMIM12
gene id: 9940:SMIM12
uniprot id: A0A6P3TTV3
names: Similarity
messages: Belongs to the SMIM12 family.

9940:CITED2
gene id: 9940:CITED2
uniprot id: K4PF77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9940:LOC101111904
gene id: 9940:LOC101111904
uniprot id: A0A6P3EAV3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RABGGTB
gene id: 9940:RABGGTB
uniprot id: C5IJ91
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9940:WNT5A
gene id: 9940:WNT5A
uniprot id: W5Q1D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9940:TMEM8B
gene id: 9940:TMEM8B
uniprot id: W5PQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9940:TES
gene id: 9940:TES
uniprot id: A0A836AA40
uniprot id: Q09YJ2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prickle / espinas / testin family.
messages: Cytoplasm
messages: Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with ALKBH4, talin, actin, alpha-actinin, GRIP1 and PXN (By similarity). Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer (By similarity).
messages: Interacts via LIM domain 1 with ZYX. Interacts (via LIM domain 3) with ENAH and VASP. Interacts with ALKBH4, talin, actin, alpha-actinin, GRIP1 and PXN (By similarity). Interacts (via LIM domain 2) with ACTL7A (via N-terminus). Heterodimer with ACTL7A; the heterodimer interacts with ENAH to form a heterotrimer.
messages: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor (By similarity).
messages: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor.
messages: The N-terminal and the C-terminal halves of the protein can associate with each other, thereby hindering interactions with ZYX.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: focal adhesion

9940:BIRC2
gene id: 9940:BIRC2
uniprot id: W5P941
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9940:TAS2R4
gene id: 9940:TAS2R4
uniprot id: A0A6P3TGA4
uniprot id: W5NSX7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium membrane

9940:VPS33A
gene id: 9940:VPS33A
uniprot id: A0A6P3ENM5
uniprot id: W5PPJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: clathrin-coated vesicle

9940:FBXO6
gene id: 9940:FBXO6
uniprot id: A0A835ZZH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120486
gene id: 9940:LOC101120486
uniprot id: W5QGE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9940:TTC33
gene id: 9940:TTC33
uniprot id: A0A6P3EB65
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LSM5
gene id: 9940:LSM5
uniprot id: A0A6P3E8X2
uniprot id: W5PAH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNB1
gene id: 9940:KCNB1
uniprot id: A0A6P3E9E7
uniprot id: W5PSR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: axon
messages: sarcolemma
messages: synaptosome

9940:AFAP1L1
gene id: 9940:AFAP1L1
uniprot id: A0A836AG06
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: invadopodium
messages: podosome

9940:CCNT1
gene id: 9940:CCNT1
uniprot id: A0A6P3E7Q3
uniprot id: W5QD24
names: Caution
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TFRC
gene id: 9940:TFRC
uniprot id: A0A6P3E4Z4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

9940:KCNMB1
gene id: 9940:KCNMB1
uniprot id: W5NZ82
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9940:CNPY4
gene id: 9940:CNPY4
uniprot id: A0A6P3EEB0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120367
gene id: 9940:LOC101120367
uniprot id: W5Q127
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9940:LRRC51
gene id: 9940:LRRC51
uniprot id: A0A6P3TBC4
uniprot id: W5P0W1
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ETNK1
gene id: 9940:ETNK1
uniprot id: A0A6P3TC20
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMBIM6
gene id: 9940:TMBIM6
uniprot id: W5QAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9940:ANKIB1
gene id: 9940:ANKIB1
uniprot id: A0A6P3E3V6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPHN
gene id: 9940:GPHN
uniprot id: A0A6P3E7Y9
names: Caution
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113715
gene id: 9940:LOC101113715
uniprot id: W5PCU3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9940:CLVS2
gene id: 9940:CLVS2
uniprot id: A0A6P3TJC1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

9940:ABRAXAS2
gene id: 9940:ABRAXAS2
uniprot id: W5PLJ4
names: Subcellular Location Annotation
messages: Nucleus

9940:ENOPH1
gene id: 9940:ENOPH1
uniprot id: A0A6P3EE57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113526
gene id: 9940:LOC101113526
uniprot id: W5Q6Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:FAM71B
gene id: 9940:FAM71B
uniprot id: A0A6P3E9S8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPA6
gene id: 9940:CPA6
uniprot id: W5NU87
names: Similarity
messages: Belongs to the peptidase M14 family.

9940:YIF1A
gene id: 9940:YIF1A
uniprot id: A0A6P3EFJ4
uniprot id: W5P0C3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:THBS3
gene id: 9940:THBS3
uniprot id: W5P162
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:P4HA2
gene id: 9940:P4HA2
uniprot id: A0A6P3ECP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9940:MZT2B
gene id: 9940:MZT2B
uniprot id: A0A6P3EBN2
uniprot id: W5Q617
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOZART2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome
messages: spindle

9940:IL3
gene id: 9940:IL3
uniprot id: Q06435
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Activated T-cells, mast cells, natural killer cells.
messages: Belongs to the IL-3 family.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages.
messages: Monomer.
messages: Secreted
messages: This CSF induces granulocytes, macrophages, mast cells, stem cells, erythroid cells, eosinophils and megakaryocytes.

9940:PIGH
gene id: 9940:PIGH
uniprot id: A0A6P3E7Z5
uniprot id: W5QJ53
names: Caution
names: Similarity
messages: Belongs to the PIGH family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GIMAP2
gene id: 9940:GIMAP2
uniprot id: W5NTW4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9940:CA14
gene id: 9940:CA14
uniprot id: W5QHX7
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9940:NTS
gene id: 9940:NTS
uniprot id: W5Q1D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

9940:SUPT7L
gene id: 9940:SUPT7L
uniprot id: A0A836D4F8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACAP2
gene id: 9940:ACAP2
uniprot id: A0A6P3YFE6
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A3
gene id: 9940:SLC39A3
uniprot id: A0A6P3TDB3
uniprot id: B2MVY1
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NIT1
gene id: 9940:NIT1
uniprot id: A0A6P3TKB8
names: Caution
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOP58
gene id: 9940:NOP58
uniprot id: A0A6P3THV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:RBBP8
gene id: 9940:RBBP8
uniprot id: W5PEG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

9940:TDRD3
gene id: 9940:TDRD3
uniprot id: W5P8D4
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in dimethylarginine-containing proteins.

9940:HOXC10
gene id: 9940:HOXC10
uniprot id: W5Q495
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9940:CD28
gene id: 9940:CD28
uniprot id: O97630
names: Subcellular Location Annotation
messages: Membrane

9940:ARSL
gene id: 9940:ARSL
uniprot id: W5PFA5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9940:CCNB3
gene id: 9940:CCNB3
uniprot id: W5PJK4
names: Similarity
messages: Belongs to the cyclin family.

9940:LSM3
gene id: 9940:LSM3
uniprot id: A0A6P3ECF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3B
gene id: 9940:POLR3B
uniprot id: A0A6P3E830
names: Caution
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PEX2
gene id: 9940:PEX2
uniprot id: A0A6P3TQH4
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

9940:TNFRSF11B
gene id: 9940:TNFRSF11B
uniprot id: A0A6P3EGC4
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123544
gene id: 9940:LOC101123544
uniprot id: A0A6P3E8D4
uniprot id: W5PWY3
names: Caution
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNA2
gene id: 9940:KCNA2
uniprot id: A0A6P3DZ92
uniprot id: W5PQ46
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

9940:SDR9C7
gene id: 9940:SDR9C7
uniprot id: W5PDY4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:AK5
gene id: 9940:AK5
uniprot id: W5PTS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm

9940:FSHB
gene id: 9940:FSHB
uniprot id: P01227
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer. The active follitropin is a heterodimer composed of an alpha chain/CGA shared with other hormones and a unique beta chain/FSHB shown here.
messages: Secreted
messages: Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs.

9940:BTG3
gene id: 9940:BTG3
uniprot id: A0A6P9FQP2
uniprot id: F4MJ46
names: Caution
names: Similarity
messages: Belongs to the BTG family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116064
gene id: 9940:LOC101116064
uniprot id: W5PF89
names: Subcellular Location Annotation
messages: Chromosome

9940:MAP1LC3C
gene id: 9940:MAP1LC3C
uniprot id: W5PAW4
names: Similarity
messages: Belongs to the ATG8 family.

9940:WDR5B
gene id: 9940:WDR5B
uniprot id: A0A6P3E6S6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TGFB1
gene id: 9940:TGFB1
uniprot id: P50414
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with TGF-beta receptors (TGFBR1 and TGFBR2), leading to signal transduction.
messages: Homodimer; disulfide-linked. Interacts with the serine proteases, HTRA1 and HTRA3: the interaction with either inhibits TGFB1-mediated signaling and the HTRA protease activity is required for this inhibition. May interact with THSD4; this interaction may lead to sequestration by FBN1 microfibril assembly and attenuation of TGFB signaling. Interacts with CD109, DPT and ASPN. Interacts with EFEMP2. Interacts with TSKU; the interaction contributes to regulation of the hair cycle.
messages: Homodimer; disulfide-linked. Interacts with transforming growth factor beta-1 (TGF-beta-1) chain; interaction is non-covalent and maintains TGF-beta-1 in a latent state; each latency-associated peptide (LAP) monomer interacts with TGF-beta-1 in the other monomer. Interacts with LTBP1; leading to regulation of TGF-beta-1 activation. Interacts with LRRC32/GARP; leading to regulation of TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs). Interacts with LRRC33/NRROS; leading to regulation of TGF-beta-1 activation in macrophages and microglia. Interacts (via cell attachment site) with integrins ITGAV and ITGB6 (ITGAV:ITGB6), leading to release of the active TGF-beta-1. Interacts with NREP; the interaction results in a decrease in TGFB1 autoinduction. Interacts with HSP90AB1; inhibits latent TGFB1 activation.
messages: Multifunctional protein that regulates the growth and differentiation of various cell types and is involved in various processes, such as normal development, immune function, microglia function and responses to neurodegeneration (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains remain non-covalently linked rendering TGF-beta-1 inactive during storage in extracellular matrix. At the same time, LAP chain interacts with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS that control activation of TGF-beta-1 and maintain it in a latent state during storage in extracellular milieus. TGF-beta-1 is released from LAP by integrins (ITGAV:ITGB6 or ITGAV:ITGB8): integrin-binding to LAP stabilizes an alternative conformation of the LAP bowtie tail and results in distortion of the LAP chain and subsequent release of the active TGF-beta-1. Once activated following release of LAP, TGF-beta-1 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal (By similarity). While expressed by many cells types, TGF-beta-1 only has a very localized range of action within cell environment thanks to fine regulation of its activation by Latency-associated peptide chain (LAP) and 'milieu molecules'. Plays an important role in bone remodeling: acts as a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. Can promote either T-helper 17 cells (Th17) or regulatory T-cells (Treg) lineage differentiation in a concentration-dependent manner. At high concentrations, leads to FOXP3-mediated suppression of RORC and down-regulation of IL-17 expression, favoring Treg cell development. At low concentrations in concert with IL-6 and IL-21, leads to expression of the IL-17 and IL-23 receptors, favoring differentiation to Th17 ce…
messages: N-glycosylated. Deglycosylation leads to activation of Transforming growth factor beta-1 (TGF-beta-1); mechanisms triggering deglycosylation-driven activation of TGF-beta-1 are however unclear.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Secreted
messages: The 'straitjacket' and 'arm' domains encircle the Transforming growth factor beta-1 (TGF-beta-1) monomers and are fastened together by strong bonding between Lys-56 and Tyr-103/Tyr-104.
messages: The cell attachment site motif mediates binding to integrins (ITGAV:ITGB6 or ITGAV:ITGB8). The motif locates to a long loop in the arm domain called the bowtie tail. Integrin-binding stabilizes an alternative conformation of the bowtie tail. Activation by integrin requires force application by the actin cytoskeleton, which is resisted by the 'milieu molecules' (such as LTBP1, LRRC32/GARP and/or LRRC33/NRROS), resulting in distortion of the prodomain and release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: Transforming growth factor beta-1 proprotein: The precursor proprotein is cleaved in the Golgi apparatus by FURIN to form Transforming growth factor beta-1 (TGF-beta-1) and Latency-associated peptide (LAP) chains, which remain non-covalently linked, rendering TGF-beta-1 inactive.
messages: extracellular matrix

9940:SNX3
gene id: 9940:SNX3
uniprot id: A0A6P3EGU7
uniprot id: W5PMB1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome
messages: Endosome
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: phagosome

9940:LOC101121590
gene id: 9940:LOC101121590
uniprot id: W5QGS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

9940:VRK1
gene id: 9940:VRK1
uniprot id: A0A6P3YRD5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:IL17A
gene id: 9940:IL17A
uniprot id: W5PWW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9940:RPL37
gene id: 9940:RPL37
uniprot id: A0A6P3ELS3
uniprot id: W5P472
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRARG1
gene id: 9940:TRARG1
uniprot id: A0A6P3E9T3
uniprot id: W5PMV3
names: Caution
names: Similarity
messages: Belongs to the CD225/Dispanin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPLX2
gene id: 9940:CPLX2
uniprot id: A0A6P3TQ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9940:PAPPA2
gene id: 9940:PAPPA2
uniprot id: W5PZE1
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:PRMT6
gene id: 9940:PRMT6
uniprot id: A0A6P3E5F5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EFNB3
gene id: 9940:EFNB3
uniprot id: A0A6P3ED61
uniprot id: W5Q2X9
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF445
gene id: 9940:ZNF445
uniprot id: A0A6P3TDT5
uniprot id: A0A6P7D5K4
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CBLIF
gene id: 9940:CBLIF
uniprot id: W5PRU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9940:HNRNPK
gene id: 9940:HNRNPK
uniprot id: A0A6P3E105
uniprot id: W5Q2G6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9940:LOC101107125
gene id: 9940:LOC101107125
uniprot id: A0A6P3EFM0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGLS
gene id: 9940:PGLS
uniprot id: A0A6P3E5F6
uniprot id: W5Q4B6
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CGA
gene id: 9940:CGA
uniprot id: A0A836CZH3
uniprot id: P01218
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin (By similarity). The alpha chain can also be formed by LH alpha 1-1, LH alpha 1-2 and LH alpha 1-3.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118549
gene id: 9940:LOC101118549
uniprot id: W5PAP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with terf2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with terf2 or other factors, and regulates gene expression.
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Nucleus
messages: telomere

9940:RMDN3
gene id: 9940:RMDN3
uniprot id: A0A6P7EA82
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP37
gene id: 9940:USP37
uniprot id: W5QEA5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9940:LOC101109919
gene id: 9940:LOC101109919
uniprot id: A0A836CVN3
uniprot id: W5QGB5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STX18
gene id: 9940:STX18
uniprot id: A0A6P3EAK7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104356
gene id: 9940:LOC101104356
uniprot id: W5Q1D3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101102091
gene id: 9940:LOC101102091
uniprot id: A0A6P3EE39
uniprot id: W5Q6X8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120084
gene id: 9940:LOC101120084
uniprot id: A0A836AFS8
uniprot id: W5PJL5
names: Caution
names: Similarity
messages: Belongs to the sulfotransferase 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STOML2
gene id: 9940:STOML2
uniprot id: A0A6P3E181
uniprot id: W5PRD7
names: Caution
names: Similarity
messages: Belongs to the band 7/mec-2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF168
gene id: 9940:RNF168
uniprot id: A0A6P3E6U0
uniprot id: W5QGI9
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to a well-established model, RNF168 cannot initiate H2A 'Lys-63'-linked ubiquitination and is recruited following RNF8-dependent histone ubiquitination to amplify H2A 'Lys-63'-linked ubiquitination. However, other data suggest that RNF168 is the priming ubiquitin ligase by mediating monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub respectively). These data suggest that RNF168 might be recruited to DSBs sites in a RNF8-dependent manner by binding to non-histone proteins ubiquitinated via 'Lys-63'-linked and initiates monoubiquitination of H2A, which is then amplified by RNF8. Additional evidences are however required to confirm these data.
messages: Belongs to the RNF168 family.
messages: E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recruited at DNA interstrand cross-links (ICLs) sites and promotes accumulation of 'Lys-63'-linked ubiquitination of histones H2A and H2AX, leading to recruitment of FAAP20 and Fanconi anemia (FA) complex, followed by interstrand cross-link repair. H2A ubiquitination also mediates the ATM-dependent transcriptional silencing at regions flanking DSBs in cis, a mechanism to avoid collision between transcription and repair intermediates. Also involved in class switch recombination in immune system, via its role in regulation of DSBs repair. Following DNA damage, promotes the ubiquitination and degradation of JMJD2A/KDM4A in collaboration with RNF8, leading to unmask H4K20me2 mark and promote the recruitment of TP53BP1 at DNA damage sites. Not able to initiate 'Lys-63'-linked ubiquitination in vitro; possibly due to partial occlusion of the UBE2N/UBC13-binding region. Catalyzes monoubiquitination of 'Lys-13' and 'Lys-15' of nucleosomal histone H2A (H2AK13Ub and H2AK15Ub, respectively).
messages: Monomer. Interacts with UBE2N/UBC13.
messages: Nucleus
messages: Sumoylated with SUMO1 by PIAS4 in response to double-strand breaks (DSBs).
messages: The MIU motif (motif interacting with ubiquitin) mediates the interaction with both 'Lys-48'- and 'Lys-63'-linked ubiquitin chains. The UMI motif mediates interaction with ubiquitin with a preference for 'Lys-63'-linked ubiquitin. The specificity for different types of ubiquitin is mediated by juxtaposition of ubiquitin-binding motifs (MIU and UMI motifs) with LR motifs (LRMs).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Ubiquitinated.

9940:FAM162A
gene id: 9940:FAM162A
uniprot id: A0A6P3E078
uniprot id: W5QFW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TYMS
gene id: 9940:TYMS
uniprot id: W5PHY4
names: Similarity
messages: Belongs to the thymidylate synthase family.

9940:ANAPC10
gene id: 9940:ANAPC10
uniprot id: A0A6P3EDU2
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

9940:SLC14A1
gene id: 9940:SLC14A1
uniprot id: C5MK33
uniprot id: W5NWJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Homotrimer; each subunit contains a pore through which urea permeates (By similarity). Identified in a complex with STOM (By similarity).
messages: Mediates the transport of urea driven by a concentration gradient across the cell membranes of erythrocytes and the renal inner medullary collecting duct which is critical to the urinary concentrating mechanism (By similarity). Facilitates water transport in erythrocytes (By similarity).
messages: Membrane

9940:LMNB1
gene id: 9940:LMNB1
uniprot id: A0A6P3E4M2
uniprot id: W5Q9T3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: Nucleus lamina
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPACA3
gene id: 9940:SPACA3
uniprot id: D7R6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Interacts with ASTL.
messages: Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.

9940:ITGB1BP2
gene id: 9940:ITGB1BP2
uniprot id: A0A6P3EN08
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLIC4
gene id: 9940:CLIC4
uniprot id: A0A6P3E1Y6
uniprot id: W5P8X9
names: Caution
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108600
gene id: 9940:LOC101108600
uniprot id: A0A6P3YLS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AKR1A1
gene id: 9940:AKR1A1
uniprot id: W5NUN8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9940:ARSA
gene id: 9940:ARSA
uniprot id: A0A6P3E8H2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9940:DYNC1I1
gene id: 9940:DYNC1I1
uniprot id: W5P0S4
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9940:KHDC4
gene id: 9940:KHDC4
uniprot id: A0A6P3E7A3
names: Caution
names: Similarity
messages: Belongs to the KHDC4 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPT1
gene id: 9940:PPT1
uniprot id: A0A836AF59
names: Caution
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBXL12
gene id: 9940:FBXL12
uniprot id: A0A6P3E9A0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNASEK
gene id: 9940:RNASEK
uniprot id: A0A6P3EIF2
uniprot id: W5PIA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase K family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115064
gene id: 9940:LOC101115064
uniprot id: W5PAG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:KCNJ12
gene id: 9940:KCNJ12
uniprot id: A0A6P3EH92
uniprot id: A0A6P7EH40
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ12 subfamily.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109271
gene id: 9940:LOC101109271
uniprot id: A0A836A326
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WASF2
gene id: 9940:WASF2
uniprot id: W5NZP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9940:IL4
gene id: 9940:IL4
uniprot id: P30368
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-4/IL-13 family.
messages: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
messages: Secreted

9940:P3H2
gene id: 9940:P3H2
uniprot id: A0A6P3YH39
names: Caution
names: Similarity
messages: Belongs to the leprecan family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EMC6
gene id: 9940:EMC6
uniprot id: A0A6P3EH13
uniprot id: W5P280
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UGT1A9
gene id: 9940:UGT1A9
uniprot id: Q9XS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:POGLUT2
gene id: 9940:POGLUT2
uniprot id: W5P5B4
names: Similarity
messages: Belongs to the KDELC family.

9940:GPR15
gene id: 9940:GPR15
uniprot id: A0A6P3E7R3
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STX17
gene id: 9940:STX17
uniprot id: W5PMN4
names: Similarity
messages: Belongs to the syntaxin family.

9940:UCN
gene id: 9940:UCN
uniprot id: W5QDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

9940:CD1
gene id: 9940:CD1
uniprot id: Q28565
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
messages: Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
messages: Cell membrane
messages: During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes or lysosomes, before trafficking back to the cell surface. Interaction with saposin C is required for the loading of bacterial lipid antigens onto CD1B in the lysosome (By similarity).
messages: Endosome membrane
messages: Heterodimer with B2M (beta-2-microglobulin). Interacts with saposin C (By similarity).
messages: Lysosome membrane

9940:XRN1
gene id: 9940:XRN1
uniprot id: A0A6P3E7N0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUDCD3
gene id: 9940:NUDCD3
uniprot id: A0A6P3E516
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115538
gene id: 9940:LOC101115538
uniprot id: A0A6P3EEJ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ECSIT
gene id: 9940:ECSIT
uniprot id: W5QB33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

9940:RACK1
gene id: 9940:RACK1
uniprot id: A0A6P9FQX8
uniprot id: S4TZR5
names: Caution
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRT71
gene id: 9940:KRT71
uniprot id: A0A6P3CY35
uniprot id: G3ER51
names: Caution
names: Similarity
messages: Belongs to the intermediate filament family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DTD2
gene id: 9940:DTD2
uniprot id: W5P8M0
names: Similarity
messages: Belongs to the DTD family.

9940:LOC101120675
gene id: 9940:LOC101120675
uniprot id: W5P260
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PHC3
gene id: 9940:PHC3
uniprot id: W5NQI9
names: Subcellular Location Annotation
messages: Nucleus

9940:PIK3IP1
gene id: 9940:PIK3IP1
uniprot id: A0A6P3YNG6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:CTNNA1
gene id: 9940:CTNNA1
uniprot id: A0A6P7E7A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

9940:ELF4
gene id: 9940:ELF4
uniprot id: A0A6P3T7K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9940:TRIM33
gene id: 9940:TRIM33
uniprot id: A0A6P3DYS0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IZUMO3
gene id: 9940:IZUMO3
uniprot id: W5PYL2
names: Similarity
messages: Belongs to the Izumo family.

9940:LOC101110777
gene id: 9940:LOC101110777
uniprot id: A0A6P3TWI2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAIM2
gene id: 9940:FAIM2
uniprot id: W5Q9X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9940:SHROOM1
gene id: 9940:SHROOM1
uniprot id: W5PUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9940:B3GAT3
gene id: 9940:B3GAT3
uniprot id: A0A6P3EDA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLN5
gene id: 9940:CLN5
uniprot id: A2TJ54
names: Disease Annotation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CLN5 family.
messages: Can undergo proteolytic cleavage at the C-terminus, probably by a cysteine protease and may involve the removal of approximately 10-15 residues from the C-terminal end.
messages: Defects in CLN5 are the cause of neuronal ceroid lipofuscinosis (NCL). NCL is characterized by brain atrophy and the accumulation of lysosome derived fluorescent storage bodies in neurons and most other cells. NCL is found in New Zealand Borderdale sheep.
messages: Interacts with SORT1, RAB5A and RAB7A. Interacts with PPT1, TPP1, CLN3, CLN6, CLN8, ATP5F1A and ATP5F1B.
messages: Lysosome
messages: Membrane
messages: N-glycosylated with both high mannose and complex type sugars. Glycosylation is important for proper folding and trafficking to the lysosomes.
messages: Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane.
messages: The type II membrane signal anchor is proteolytically cleaved to produce a mature form that is transported to the lysosomes (Ceroid-lipofuscinosis neuronal protein 5, secreted form).

9940:FAM216B
gene id: 9940:FAM216B
uniprot id: W5PBZ4
names: Similarity
messages: Belongs to the FAM216 family.

9940:TP53RK
gene id: 9940:TP53RK
uniprot id: A0A6P3EC06
uniprot id: W5PHA6
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SOX2
gene id: 9940:SOX2
uniprot id: A0A0N9XTU0
uniprot id: A0A836D8U9
uniprot id: P54231
names: Caution
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with ZSCAN10 (By similarity). Interacts with SOX3 and FGFR1 (By similarity). Interacts with GLIS1 (By similarity). Interacts with POU5F1; binds synergistically with POU5F1 to DNA (By similarity). Interacts with DDX56 (By similarity).
messages: Nucleus
messages: Sumoylation inhibits DNA binding and negatively regulates the FGF4 transactivation.
messages: The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Binds to the proximal enhancer region of NANOG (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). May function as a switch in neuronal development (By similarity).

9940:SLC28A3
gene id: 9940:SLC28A3
uniprot id: W5PGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9940:FRK
gene id: 9940:FRK
uniprot id: W5PI49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9940:EBF1
gene id: 9940:EBF1
uniprot id: A0A6P3TSP4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STK32A
gene id: 9940:STK32A
uniprot id: W5NZQ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:PCOLCE
gene id: 9940:PCOLCE
uniprot id: W5Q517
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:LOC101108251
gene id: 9940:LOC101108251
uniprot id: W5P8D0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:C3AR1
gene id: 9940:C3AR1
uniprot id: W5QGJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

9940:CTTNBP2
gene id: 9940:CTTNBP2
uniprot id: Q09YI1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CTTN/cortactin SH3 domain. Interacts with STRN, STRN4/zinedin and MOB4/phocein; this interaction may regulate dendritic spine distribution of STRN and STRN4 in hippocampal neurons. Activation of glutamate receptors weakens the interaction with STRN and STRN4.
messages: Regulates the dendritic spine distribution of CTTN/cortactin in hippocampal neurons, thus controls dendritic spinogenesis and dendritic spine maintenance.
messages: cell cortex
messages: dendritic spine

9940:IGFBP1
gene id: 9940:IGFBP1
uniprot id: B9VQ08
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds equally well IGF1 and IGF2.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:C3H12orf4
gene id: 9940:C3H12orf4
uniprot id: A0A6P3E8C3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V1G2
gene id: 9940:ATP6V1G2
uniprot id: A0A6P3ENV2
uniprot id: W5PG22
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:CYB5A
gene id: 9940:CYB5A
uniprot id: A0A6P9FQQ0
uniprot id: C9E8M7
names: Caution
names: Similarity
messages: Belongs to the cytochrome b5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM19
gene id: 9940:TMEM19
uniprot id: W5PZ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

9940:EBI3
gene id: 9940:EBI3
uniprot id: A0A836A609
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFXN5
gene id: 9940:SFXN5
uniprot id: A0A6P3E2R0
uniprot id: W5PPW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FGF1
gene id: 9940:FGF1
uniprot id: A0A836A6A4
uniprot id: Q7M303
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: In the nucleus, phosphorylated by PKC/PRKCD.
messages: Monomer. Homodimer. Interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Found in a complex with FGFBP1, FGF1 and FGF2. Interacts with FGFBP1. Part of a Cu(2+)-dependent multiprotein aggregate containing FGF1, S100A13 and SYT1. Interacts with SYT1. Interacts with S100A13 (By similarity). Interacts with LRRC59 (By similarity). Interacts with CSNKA, CSNKB and FIBP (By similarity). While binding with LRRC59, CSNKA and FIBP seem mutually exclusive, CSNKB and FIBP may cooperatively interact with FGF1. Forms a ternary complex with FGFR1 and ITGAV:ITGB3 and induces the recruitment of PTPN11 to the complex (By similarity).
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. Can induce angiogenesis.
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cell cortex
messages: cytosol

9940:FGF7
gene id: 9940:FGF7
uniprot id: A0A6P3TF60
uniprot id: B2MVW3
uniprot id: W5QIL6
names: Caution
names: Similarity
messages: Belongs to the heparin-binding growth factors family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLCC1
gene id: 9940:CLCC1
uniprot id: A0A6P3DYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane
messages: Nucleus membrane

9940:KYNU
gene id: 9940:KYNU
uniprot id: A0A6P3E1G7
uniprot id: W5PJN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM210A
gene id: 9940:FAM210A
uniprot id: A0A6P3ER97
uniprot id: A0A6P3TJF4
names: Caution
names: Similarity
messages: Belongs to the FAM210 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ETS1
gene id: 9940:ETS1
uniprot id: W5PUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

9940:SLC51B
gene id: 9940:SLC51B
uniprot id: A0A6P3EFH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121706
gene id: 9940:LOC101121706
uniprot id: W5PAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SNCG
gene id: 9940:SNCG
uniprot id: A0A6P3ES45
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPS27
gene id: 9940:MRPS27
uniprot id: W5P4Z8
names: Subcellular Location Annotation
messages: Mitochondrion

9940:LPGAT1
gene id: 9940:LPGAT1
uniprot id: W5PP09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

9940:SASS6
gene id: 9940:SASS6
uniprot id: W5Q944
names: Subcellular Location Annotation
messages: centrosome

9940:LOC101122801
gene id: 9940:LOC101122801
uniprot id: W5PXK9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9940:AKR1B1
gene id: 9940:AKR1B1
uniprot id: W5PC00
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:LIN28B
gene id: 9940:LIN28B
uniprot id: A0A411PNQ7
uniprot id: H6WP39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

9940:MMP27
gene id: 9940:MMP27
uniprot id: W5P6G5
names: Similarity
messages: Belongs to the peptidase M10A family.

9940:RITA1
gene id: 9940:RITA1
uniprot id: W5PFG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

9940:TYW5
gene id: 9940:TYW5
uniprot id: A0A6P3E6G7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFNT6
gene id: 9940:IFNT6
uniprot id: A0A836ALP8
uniprot id: Q29429
names: Caution
names: Developmental Stage
names: Function
names: Miscellaneous
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Constitutively and exclusively expressed in the mononuclear cells of the extraembryonic trophectoderm.
messages: IFN-tau genes are intronless. They evolved from IFN-omega genes in the ruminantia suborder and have continued to duplicate independently in different lineages of the ruminantia. They code for proteins very similar in sequence but with different biological potency and pattern of expression.
messages: Major secretory product synthesized by the sheep conceptus between days 13 and 21 of pregnancy.
messages: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: There seems to be four variants of IFN-tau 6: A/p6V3, B/p6V2, C/p6V1 and D/P6/p12 (shown here).

9940:MRPS14
gene id: 9940:MRPS14
uniprot id: A0A6P3EJU2
uniprot id: W5PWH1
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGRMC1
gene id: 9940:PGRMC1
uniprot id: A0A6P9FRJ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFC2
gene id: 9940:NDUFC2
uniprot id: A0A6P3ED46
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC2 subunit family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NADK
gene id: 9940:NADK
uniprot id: W5NVE9
names: Similarity
messages: Belongs to the NAD kinase family.

9940:NUDT21
gene id: 9940:NUDT21
uniprot id: A0A6P3EFC9
uniprot id: W5QAS3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family. CPSF5 subfamily.
messages: Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The CFIm complex acts as a key regulator of cleavage and polyadenylation site choice during APA through its binding to 5'-UGUA-3' elements localized in the 3'-untranslated region (UTR) for a huge number of pre-mRNAs.
messages: Cytoplasm
messages: Homodimer (via N- and C-terminus); binds RNA as homodimer. Component of the cleavage factor Im (CFIm) complex.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CAPNS1
gene id: 9940:CAPNS1
uniprot id: W5P5G5
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

9940:TYROBP
gene id: 9940:TYROBP
uniprot id: A0A6P3ELB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110824
gene id: 9940:LOC101110824
uniprot id: A0A6P3TLP1
names: Caution
names: Similarity
messages: Belongs to the cystatin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFRSF1A
gene id: 9940:TNFRSF1A
uniprot id: C8BKB9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:ANGPT1
gene id: 9940:ANGPT1
uniprot id: A0A6P3EGD4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109111
gene id: 9940:LOC101109111
uniprot id: W5PN69
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:SCUBE2
gene id: 9940:SCUBE2
uniprot id: W5PVQ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:ELAVL1
gene id: 9940:ELAVL1
uniprot id: A0A6P9FQK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

9940:TPX2
gene id: 9940:TPX2
uniprot id: A0A6P7ENX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9940:MINAR1
gene id: 9940:MINAR1
uniprot id: W5Q0B9
names: Similarity
messages: Belongs to the MINAR family.

9940:ST3GAL5
gene id: 9940:ST3GAL5
uniprot id: S5M610
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9940:TAS1R1
gene id: 9940:TAS1R1
uniprot id: A0A6P3E8X9
uniprot id: W5PPL9
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107047
gene id: 9940:LOC101107047
uniprot id: A0A6P3EE05
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC181
gene id: 9940:CCDC181
uniprot id: A0A6P3TXM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC181 family.
messages: Microtubule-binding protein that localizes to the microtubular manchette of elongating spermatids.
messages: cytoskeleton
messages: flagellum

9940:ADRA1A
gene id: 9940:ADRA1A
uniprot id: A0A6P3E7Y7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: caveola

9940:LOC101113524
gene id: 9940:LOC101113524
uniprot id: A0A6P3ELT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTBP3
gene id: 9940:PTBP3
uniprot id: A0A6P3YHE2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RIOK2
gene id: 9940:RIOK2
uniprot id: W5Q9S9
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9940:EPCAM
gene id: 9940:EPCAM
uniprot id: C5ISB0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lateral cell membrane
messages: May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
messages: Membrane
messages: tight junction

9940:LOC101112029
gene id: 9940:LOC101112029
uniprot id: A0A6P3EMY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:CEP41
gene id: 9940:CEP41
uniprot id: A0A836AAH6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSME1
gene id: 9940:PSME1
uniprot id: A0A6P3EEM0
uniprot id: W5QD49
names: Caution
names: Similarity
messages: Belongs to the PA28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FGB
gene id: 9940:FGB
uniprot id: A0A836CUX2
uniprot id: W5NQ46
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HARS1
gene id: 9940:HARS1
uniprot id: W5QAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

9940:PPEF1
gene id: 9940:PPEF1
uniprot id: A0A6P3THC6
names: Similarity
messages: Belongs to the PPP phosphatase family.

9940:SRP72
gene id: 9940:SRP72
uniprot id: W5P2J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

9940:S100A13
gene id: 9940:S100A13
uniprot id: A0A6P3EFJ7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLP1
gene id: 9940:PLP1
uniprot id: W5NQW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9940:LOC101104933
gene id: 9940:LOC101104933
uniprot id: A0A6P3EAU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACE2
gene id: 9940:ACE2
uniprot id: A0A6P3TFC0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium

9940:DCTN5
gene id: 9940:DCTN5
uniprot id: A0A6P3ELL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB4
gene id: 9940:PSMB4
uniprot id: W5QIL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

9940:MMAA
gene id: 9940:MMAA
uniprot id: A0A6P3EBB5
names: Caution
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1H1orf43
gene id: 9940:C1H1orf43
uniprot id: A0A836D6Z9
uniprot id: W5NVE4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NAA60
gene id: 9940:NAA60
uniprot id: A0A6P3T5N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. NAA60 subfamily.
messages: Golgi apparatus membrane

9940:VAMP4
gene id: 9940:VAMP4
uniprot id: A0A6P3EE46
uniprot id: W5PW08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NEFM
gene id: 9940:NEFM
uniprot id: W5PJQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

9940:CALR
gene id: 9940:CALR
uniprot id: A0A6P3E5I0
uniprot id: A0A6P7E595
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GTF2A2
gene id: 9940:GTF2A2
uniprot id: A0A6P3EF18
uniprot id: A0A6P7DBL1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC38A9
gene id: 9940:SLC38A9
uniprot id: A0A6P3EDN5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119629
gene id: 9940:LOC101119629
uniprot id: A0A6P3E3J1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:F8
gene id: 9940:F8
uniprot id: D3IU20
names: Similarity
messages: Belongs to the multicopper oxidase family.

9940:MRPS22
gene id: 9940:MRPS22
uniprot id: A0A6P3E0H4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107221
gene id: 9940:LOC101107221
uniprot id: A0A6P3EAU9
uniprot id: W5PC30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL31
gene id: 9940:RPL31
uniprot id: W5PUU0
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

9940:SERPINE1
gene id: 9940:SERPINE1
uniprot id: D4N532
names: Similarity
messages: Belongs to the serpin family.

9940:SMIM3
gene id: 9940:SMIM3
uniprot id: A0A6P3E9R8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL33
gene id: 9940:IL33
uniprot id: A0A836D8X1
uniprot id: W5PVY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family. Highly divergent.
messages: Chromosome
messages: Nucleus
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle
messages: secretory vesicle

9940:ACKR4
gene id: 9940:ACKR4
uniprot id: A0A6P7DC27
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:LOC101110394
gene id: 9940:LOC101110394
uniprot id: A0A836ANA0
uniprot id: W5QAB9
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF26
gene id: 9940:RNF26
uniprot id: A0A6P3EK95
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104500
gene id: 9940:LOC101104500
uniprot id: A0A6P3EBW0
uniprot id: W5NWY6
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL2RG
gene id: 9940:IL2RG
uniprot id: A0A835ZKE8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF518B
gene id: 9940:ZNF518B
uniprot id: A0A6P3YJU6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRPT1
gene id: 9940:TRPT1
uniprot id: A0A6P3TD21
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

9940:SBD2
gene id: 9940:SBD2
uniprot id: E2ITD7
names: Subcellular Location Annotation
messages: Secreted

9940:POLH
gene id: 9940:POLH
uniprot id: W5PD86
names: Subcellular Location Annotation
messages: Nucleus

9940:NKX3-1
gene id: 9940:NKX3-1
uniprot id: W5PK28
names: Subcellular Location Annotation
messages: Nucleus

9940:CASP8
gene id: 9940:CASP8
uniprot id: A0A6P3T9A7
uniprot id: A0A6P3TJN8
names: Caution
names: Similarity
messages: Belongs to the peptidase C14A family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC7A11
gene id: 9940:SLC7A11
uniprot id: A0A6P3TA75
uniprot id: G3FHC4
uniprot id: H2EUS8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL36AL
gene id: 9940:RPL36AL
uniprot id: A0A6P3EEZ5
uniprot id: W5NRQ6
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CATSPERZ
gene id: 9940:CATSPERZ
uniprot id: A0A835ZUG8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRT35
gene id: 9940:KRT35
uniprot id: B0LKP1
names: Miscellaneous
names: Similarity
messages: Belongs to the intermediate filament family.
messages: There are two types of hair/microfibrillar keratin, I (acidic) and II (neutral to basic).

9940:FARSA
gene id: 9940:FARSA
uniprot id: W5PJU6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

9940:SMIM20
gene id: 9940:SMIM20
uniprot id: A0A6P3E5E5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HIGD1A
gene id: 9940:HIGD1A
uniprot id: A0A835ZMU2
uniprot id: W5Q7R3
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FGF5
gene id: 9940:FGF5
uniprot id: I6WYL7
uniprot id: I6XXC7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heparin-binding growth factors family.
messages: Interacts with FGFR1 and FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
messages: Plays an important role in the regulation of cell proliferation and cell differentiation. Required for normal regulation of the hair growth cycle. Functions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
messages: Secreted

9940:LOC101106976
gene id: 9940:LOC101106976
uniprot id: A0A836CS49
names: Caution
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNOT6L
gene id: 9940:CNOT6L
uniprot id: A0A6P3EE53
uniprot id: A0A6P3YM05
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADGRG7
gene id: 9940:ADGRG7
uniprot id: A0A836AHB3
uniprot id: W5Q9J5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108520
gene id: 9940:LOC101108520
uniprot id: A0A6P3EBX9
uniprot id: A0A6P3T2M4
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121048
gene id: 9940:LOC101121048
uniprot id: A0A835ZQD8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116371
gene id: 9940:LOC101116371
uniprot id: W5NRV6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9940:LOC101119808
gene id: 9940:LOC101119808
uniprot id: A0A836D814
uniprot id: W5QA96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BRPF1
gene id: 9940:BRPF1
uniprot id: W5P8K3
uniprot id: W5P8K6
names: Subcellular Location Annotation
messages: Nucleus

9940:PTAR1
gene id: 9940:PTAR1
uniprot id: A0A836AAB2
names: Caution
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB39B
gene id: 9940:RAB39B
uniprot id: A0A6P3EN47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C2H9orf64
gene id: 9940:C2H9orf64
uniprot id: W5PGP8
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

9940:LOC101109989
gene id: 9940:LOC101109989
uniprot id: A0A6P3TY83
names: Similarity
messages: Belongs to the SELO family.

9940:CAPZA1
gene id: 9940:CAPZA1
uniprot id: A0A6P3E497
uniprot id: W5Q694
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105601854
gene id: 9940:LOC105601854
uniprot id: W5PI50
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

9940:KCNC1
gene id: 9940:KCNC1
uniprot id: W5NUC4
names: Subcellular Location Annotation
messages: Membrane

9940:RPS3
gene id: 9940:RPS3
uniprot id: A0A836A242
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus
messages: spindle

9940:CS
gene id: 9940:CS
uniprot id: A0A6P3E7X6
uniprot id: W5PI34
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:B9D2
gene id: 9940:B9D2
uniprot id: A0A6P3ECE6
uniprot id: A0A6P3TZF3
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium basal body

9940:MFSD14B
gene id: 9940:MFSD14B
uniprot id: W5Q1Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9940:ZNF202
gene id: 9940:ZNF202
uniprot id: W5NRJ9
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101116903
gene id: 9940:LOC101116903
uniprot id: W5NT83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:MFAP3
gene id: 9940:MFAP3
uniprot id: A0A6P3YLZ1
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPDL1
gene id: 9940:SPDL1
uniprot id: W5NY23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Spindly family.
messages: Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
messages: Nucleus
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
messages: centrosome
messages: kinetochore
messages: spindle pole

9940:FABP3
gene id: 9940:FABP3
uniprot id: A0A6P3TBK2
uniprot id: I1ZAM7
uniprot id: W5NU39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118250
gene id: 9940:LOC101118250
uniprot id: A0A6P3EHI3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116001
gene id: 9940:LOC101116001
uniprot id: A0A6P3E3Z5
uniprot id: W5P697
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD200
gene id: 9940:CD200
uniprot id: W5QDD1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:S100G
gene id: 9940:S100G
uniprot id: W5PU09
names: Similarity
messages: Belongs to the S-100 family.

9940:CIAPIN1
gene id: 9940:CIAPIN1
uniprot id: A0A836A1G0
uniprot id: W5NPU7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with NDOR1. Interacts with CHCHD4.
messages: Nucleus
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial CHCHD4/MIA40-GFER/ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

9940:NKIRAS2
gene id: 9940:NKIRAS2
uniprot id: A0A6P3TL64
uniprot id: W5QA55
names: Caution
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GNG11
gene id: 9940:GNG11
uniprot id: B6V716
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9940:KLK6
gene id: 9940:KLK6
uniprot id: A0A6P3TNN4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123619
gene id: 9940:LOC101123619
uniprot id: W5Q4I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9940:CDKN3
gene id: 9940:CDKN3
uniprot id: A0A836D0G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:IL17RB
gene id: 9940:IL17RB
uniprot id: A0A6P3EN68
uniprot id: W5Q2V7
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NFIL3
gene id: 9940:NFIL3
uniprot id: A0A6P3CX68
uniprot id: B7SH79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts. Represses transcriptional activity of PER1. Represses transcriptional activity of PER2 via the B-site on the promoter. Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF). Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock. Protects pro-B cells from programmed cell death.
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: Homodimer. Binds DNA as a dimer.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109676
gene id: 9940:LOC101109676
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SDHAF2
gene id: 9940:SDHAF2
uniprot id: A0A6P3EQI9
uniprot id: W5PU49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with SDHA within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPF4B
gene id: 9940:PRPF4B
uniprot id: W5NQX9
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

9940:SUSD3
gene id: 9940:SUSD3
uniprot id: W5PE64
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:SLC5A1
gene id: 9940:SLC5A1
uniprot id: A0A835ZR40
uniprot id: P53791
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Electrogenic Na(+)-coupled sugar simporter that actively transports D-glucose or D-galactose at the plasma membrane, with a Na(+) to sugar coupling ratio of 2:1. Transporter activity is driven by a transmembrane Na(+) electrochemical gradient set by the Na(+)/K(+) pump (By similarity). Has a primary role in the transport of dietary monosaccharides from enterocytes to blood. Responsible for the absorption of D-glucose or D-galactose across the apical brush-border membrane of enterocytes, whereas basolateral exit is provided by GLUT2. Additionally, functions as a D-glucose sensor in enteroendocrine cells, triggering the secretion of the incretins GCG and GIP that control food intake and energy homeostasis (By similarity). Together with SGLT2, functions in reabsorption of D-glucose from glomerular filtrate, playing a nonredundant role in the S3 segment of the proximal tubules (By similarity). Transports D-glucose into endometrial epithelial cells, controlling glycogen synthesis and nutritional support for the embryo as well as the decidual transformation of endometrium prior to conception (By similarity). Acts as a water channel enabling passive water transport in response to the osmotic gradient created upon sugar and Na(+) uptake. Has high water conductivity comparable to aquaporins and therefore is expected to play an important role in transepithelial water permeability, especially in the small intestine.
messages: Membrane
messages: N-glycosylation is not necessary for the cotransporter function.
messages: The cholesterol-binding site is formed by transmembrane helices TM1, TM7 and TM13.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PI4K2B
gene id: 9940:PI4K2B
uniprot id: A0A6P3EAA7
uniprot id: W5P9Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SIVA1
gene id: 9940:SIVA1
uniprot id: W5PD20
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis.
messages: Nucleus

9940:SLC17A6
gene id: 9940:SLC17A6
uniprot id: A0A6P3EQC9
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LARS2
gene id: 9940:LARS2
uniprot id: W5PLQ3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9940:MS4A2
gene id: 9940:MS4A2
uniprot id: W5PT67
names: Similarity
messages: Belongs to the MS4A family.

9940:DCTD
gene id: 9940:DCTD
uniprot id: A0A6P7DI23
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

9940:SELENBP1
gene id: 9940:SELENBP1
uniprot id: W5QIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

9940:PTH2R
gene id: 9940:PTH2R
uniprot id: W5QCN9
names: Subcellular Location Annotation
messages: Membrane

9940:LYPD2
gene id: 9940:LYPD2
uniprot id: A0A6P3TJS8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIGY
gene id: 9940:PIGY
uniprot id: A0A6P3TT84
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPSF3
gene id: 9940:CPSF3
uniprot id: A0A6P3EAP9
uniprot id: W5Q0D9
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTA1
gene id: 9940:ACTA1
uniprot id: A0A6P3ERW2
uniprot id: W5NYJ1
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DESI1
gene id: 9940:DESI1
uniprot id: A0A6P3E424
names: Caution
names: Similarity
messages: Belongs to the DeSI family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMPRSS13
gene id: 9940:TMPRSS13
uniprot id: W5PBU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:PRICKLE1
gene id: 9940:PRICKLE1
uniprot id: A0A6P3TEM6
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9940:RASSF3
gene id: 9940:RASSF3
uniprot id: A0A6P3E383
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RCVRN
gene id: 9940:RCVRN
uniprot id: A0A6P3YL56
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122163
gene id: 9940:LOC101122163
uniprot id: A0A6P3EGX8
uniprot id: A0A6P7ER11
names: Caution
names: Similarity
messages: Belongs to the UPF0547 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC2A3
gene id: 9940:SLC2A3
uniprot id: A0A836D4Q1
uniprot id: P47843
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Deoxyglucose transport is inhibit by D-glucose, D-galactose and maltose. Galactose transport is inhibited by D-glucose and maltose.
messages: Detected in placenta.
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Perikaryon
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

9940:PEX5
gene id: 9940:PEX5
uniprot id: A0A836D8B1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX58
gene id: 9940:DDX58
uniprot id: W5PZB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9940:IRAK1BP1
gene id: 9940:IRAK1BP1
uniprot id: W5PA12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

9940:PNN
gene id: 9940:PNN
uniprot id: W5PFN0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

9940:FAF2
gene id: 9940:FAF2
uniprot id: A0A6P3E4N2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL5
gene id: 9940:IL5
uniprot id: Q28586
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked. Interacts with IL5RA. Interacts with CSF2RB.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively (By similarity).
messages: Secreted

9940:FAM78B
gene id: 9940:FAM78B
uniprot id: A0A6P3DZA6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SERPINF1
gene id: 9940:SERPINF1
uniprot id: B6UV62
names: Similarity
messages: Belongs to the serpin family.

9940:C4H7orf57
gene id: 9940:C4H7orf57
uniprot id: A0A836D2E8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF5
gene id: 9940:EIF5
uniprot id: W5P6I6
names: Function
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.
messages: Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).

9940:DGKG
gene id: 9940:DGKG
uniprot id: A0A6P3E6W2
uniprot id: W5QH74
names: Caution
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:METTL15
gene id: 9940:METTL15
uniprot id: A0A6P7EYQ5
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

9940:DHTKD1
gene id: 9940:DHTKD1
uniprot id: W5PZN4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9940:SIX6
gene id: 9940:SIX6
uniprot id: A0A6P3CXG3
uniprot id: C5HK63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TWSG1
gene id: 9940:TWSG1
uniprot id: A0A6P3YPU1
uniprot id: W5NSD4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NLGN3
gene id: 9940:NLGN3
uniprot id: A0A6P3ESH8
uniprot id: W5Q544
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PFDN1
gene id: 9940:PFDN1
uniprot id: W5Q7Q9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9940:CCNG1
gene id: 9940:CCNG1
uniprot id: A0A6P3TRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

9940:RPS23
gene id: 9940:RPS23
uniprot id: A0A836ADF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103739
gene id: 9940:LOC101103739
uniprot id: A0A835ZW32
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115661
gene id: 9940:LOC101115661
uniprot id: A0A6P3YS37
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MARCHF7
gene id: 9940:MARCHF7
uniprot id: A0A6P3E1E5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDND1
gene id: 9940:CLDND1
uniprot id: A0A836AQL4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRC8A
gene id: 9940:LRRC8A
uniprot id: A0A6P3E215
uniprot id: A0A6P3TA94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC106991540
gene id: 9940:LOC106991540
uniprot id: W5QF62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:TMEM254
gene id: 9940:TMEM254
uniprot id: A0A6P3EMD2
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDP2
gene id: 9940:PDP2
uniprot id: W5PN71
names: Similarity
messages: Belongs to the PP2C family.

9940:LOC101119531
gene id: 9940:LOC101119531
uniprot id: A0A836D4T2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FBXO22
gene id: 9940:FBXO22
uniprot id: A0A6P3EE90
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IYD
gene id: 9940:IYD
uniprot id: A0A836A286
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD53
gene id: 9940:CD53
uniprot id: M4WHJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:ZNF280C
gene id: 9940:ZNF280C
uniprot id: A0A6P3YUF6
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9940:ATP6V1FNB
gene id: 9940:ATP6V1FNB
uniprot id: A0A6P3TLF4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ILVBL
gene id: 9940:ILVBL
uniprot id: A0A6P3E4G0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPP enzyme family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TGFB2
gene id: 9940:TGFB2
uniprot id: A0A6P3E8J6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:CRY2
gene id: 9940:CRY2
uniprot id: A0A6P3CX27
uniprot id: A0A6P7ETI3
names: Caution
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101108922
gene id: 9940:LOC101108922
uniprot id: A0A836A327
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FN3K
gene id: 9940:FN3K
uniprot id: A0A6P3E895
uniprot id: W5Q3U8
names: Caution
names: Similarity
messages: Belongs to the fructosamine kinase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SAMD4B
gene id: 9940:SAMD4B
uniprot id: A0A6P3YMJ9
uniprot id: W5P7R9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC169
gene id: 9940:CCDC169
uniprot id: A0A6P3EFG8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TP53INP1
gene id: 9940:TP53INP1
uniprot id: A0A6P3YJI5
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

9940:NFIB
gene id: 9940:NFIB
uniprot id: H9CJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTF/NF-I family.
messages: Nucleus

9940:IL16
gene id: 9940:IL16
uniprot id: W5Q2G2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homotetramer.
messages: Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4.
messages: Nucleus
messages: Secreted

9940:GOLGA7
gene id: 9940:GOLGA7
uniprot id: A0A835ZJP0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RIPPLY3
gene id: 9940:RIPPLY3
uniprot id: W5PXM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

9940:AQP5
gene id: 9940:AQP5
uniprot id: Q866S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Forms a water-specific channel (By similarity). Plays an important role in fluid secretion in salivary glands. Required for TRPV4 activation by hypotonicity. Together with TRPV4, controls regulatory volume decrease in salivary epithelial cells. Seems to play a redundant role in water transport in the eye, lung and in sweat glands (By similarity).
messages: Homotetramer. Interacts with TRPV4; the interaction is probably indirect and regulates TRPV4 activation by hypotonicity.

9940:UBE2H
gene id: 9940:UBE2H
uniprot id: W5P3W3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:FBN1
gene id: 9940:FBN1
uniprot id: A0A6P3TFV4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:DPP8
gene id: 9940:DPP8
uniprot id: A0A836AB87
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC5A6
gene id: 9940:SLC5A6
uniprot id: W5QD13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9940:ROGDI
gene id: 9940:ROGDI
uniprot id: A0A6P3ELG6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rogdi family.
messages: Perikaryon
messages: Presynapse
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: synaptic vesicle

9940:RNASEH2A
gene id: 9940:RNASEH2A
uniprot id: A0A6P3TRY4
uniprot id: A0A6P7E2N3
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNK5
gene id: 9940:KCNK5
uniprot id: W5Q4Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9940:GALR1
gene id: 9940:GALR1
uniprot id: W5P2L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9940:KIF20B
gene id: 9940:KIF20B
uniprot id: W5Q1Q1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:SPG21
gene id: 9940:SPG21
uniprot id: A0A6P3EAP4
uniprot id: A0A6P3TNN2
names: Caution
names: Function
messages: May play a role as a negative regulatory factor in CD4-dependent T-cell activation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TKT
gene id: 9940:TKT
uniprot id: A0A6P3EPF2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARF3
gene id: 9940:ARF3
uniprot id: C5IWU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9940:IL18
gene id: 9940:IL18
uniprot id: Q9GL09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: Cytoplasm
messages: Forms a ternary complex with ligand-binding receptor subunit IL18R1 and signaling receptor subunit IL18RAP at the plasma membrane. Mature IL18 first binds to IL18R1 forming a low affinity binary complex, which then interacts with IL18RAP to form a high affinity ternary complex that signals inside the cell. Interacts with cargo receptor TMED10; the interaction mediates the translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) and thereby secretion.
messages: Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted

9940:KRTAP1-1
gene id: 9940:KRTAP1-1
uniprot id: Q29619
names: Function
messages: The keratin products of mammalian epidermal derivatives such as wool and hair consist of microfibrils embedded in a rigid matrix of other proteins. The matrix proteins include the high-sulfur and high-tyrosine keratins, having molecular weights of 6-20 kDa, whereas the microfibrils contain the larger, low-sulfur keratins (40-56 kDa).

9940:MAGEH1
gene id: 9940:MAGEH1
uniprot id: A0A6P3ESD3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V1E2
gene id: 9940:ATP6V1E2
uniprot id: A0A6P3TKU3
uniprot id: A0A6P7DWN1
names: Caution
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110445
gene id: 9940:LOC101110445
uniprot id: W5PUI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:C16H5orf22
gene id: 9940:C16H5orf22
uniprot id: A0A836CXQ3
uniprot id: W5PSD9
names: Caution
names: Similarity
messages: Belongs to the UPF0489 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BLOC1S1
gene id: 9940:BLOC1S1
uniprot id: A0A6P3TK39
uniprot id: W5PNW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BLOC1S1 family.
messages: Lysosome membrane
messages: May negatively regulate aerobic respiration through mitochondrial protein lysine-acetylation. May counteract the action of the deacetylase SIRT3 by acetylating and regulating proteins of the mitochondrial respiratory chain including ATP5F1A and NDUFA9.
messages: Mitochondrion intermembrane space
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTERF1
gene id: 9940:MTERF1
uniprot id: A0A6P3TR21
names: Similarity
messages: Belongs to the mTERF family.

9940:EFNB2
gene id: 9940:EFNB2
uniprot id: W5P5Z2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:WBP4
gene id: 9940:WBP4
uniprot id: W5PAD2
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC443313
gene id: 9940:LOC443313
uniprot id: A0A6P9FNB2
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

9940:WFDC5
gene id: 9940:WFDC5
uniprot id: A0A6P3EKS7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAG3
gene id: 9940:STAG3
uniprot id: W5Q6Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9940:SF3A3
gene id: 9940:SF3A3
uniprot id: A0A6P3DYL3
uniprot id: W5QFB8
names: Caution
names: Similarity
messages: Belongs to the SF3A3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101103354
gene id: 9940:LOC101103354
uniprot id: A0A835ZNR0
uniprot id: W5PHB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL8A
gene id: 9940:ARL8A
uniprot id: A0A6P9FQK2
uniprot id: C5IWT8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Synapse
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: spindle

9940:RCBTB1
gene id: 9940:RCBTB1
uniprot id: A0A6P3YJL0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRHR
gene id: 9940:TRHR
uniprot id: A0A835ZYF4
uniprot id: Q28596
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DERL1
gene id: 9940:DERL1
uniprot id: A0A6P3EC66
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TCTN2
gene id: 9940:TCTN2
uniprot id: W5NY09
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

9940:HABP2
gene id: 9940:HABP2
uniprot id: W5PSM6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:CIB4
gene id: 9940:CIB4
uniprot id: C7A278
names: Miscellaneous
names: Subunit
names: Tissue Specificity
messages: Interacts with ITGA2B (via C-terminus cytoplasmic tail region); the interaction is stabilized/increased in a calcium- and magnesium-dependent manner.
messages: Isoform 1 and isoform 2 are expressed in testis.
messages: The binding of either calcium or magnesium may significantly increases the structural stability of the protein in comparison to apo-CIB (calcium- and magnesium-free form).

9940:TYRP1
gene id: 9940:TYRP1
uniprot id: B3VKX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9940:SUPT3H
gene id: 9940:SUPT3H
uniprot id: A0A6P3YND7
names: Subcellular Location Annotation
messages: Nucleus

9940:TGFBR1
gene id: 9940:TGFBR1
uniprot id: W5PMT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9940:KCNK6
gene id: 9940:KCNK6
uniprot id: W5P6C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9940:ADGRL4
gene id: 9940:ADGRL4
uniprot id: A0A6P3DYZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC16A3
gene id: 9940:SLC16A3
uniprot id: A0A6P3TLB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9940:AP1S2
gene id: 9940:AP1S2
uniprot id: W5PTE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

9940:MAPRE1
gene id: 9940:MAPRE1
uniprot id: A0A6P7END3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome
messages: spindle pole

9940:VBP1
gene id: 9940:VBP1
uniprot id: A0A6P3EF65
uniprot id: W5P0G8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLD1
gene id: 9940:PLD1
uniprot id: A0A6P3E0D1
names: Caution
names: Similarity
messages: Belongs to the phospholipase D family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS15A
gene id: 9940:RPS15A
uniprot id: A0A836A542
uniprot id: W5P2W9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDH11
gene id: 9940:CDH11
uniprot id: A0A6P3YLJ2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX39B
gene id: 9940:DDX39B
uniprot id: A0A835ZP30
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEPTIN3
gene id: 9940:SEPTIN3
uniprot id: W5QBV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9940:APOBEC4
gene id: 9940:APOBEC4
uniprot id: A0A6P3TU66
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRPPRC
gene id: 9940:LRPPRC
uniprot id: A0A836D3G6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VSNL1
gene id: 9940:VSNL1
uniprot id: W5Q515
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

9940:PRKAB2
gene id: 9940:PRKAB2
uniprot id: W5QH48
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9940:SLC39A14
gene id: 9940:SLC39A14
uniprot id: A0A6P3YJQ8
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111463
gene id: 9940:LOC101111463
uniprot id: A0A6P3EHZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:OGT
gene id: 9940:OGT
uniprot id: A0A6P3ES33
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:METTL21C
gene id: 9940:METTL21C
uniprot id: A0A6P7EEI0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MMUT
gene id: 9940:MMUT
uniprot id: A0A6P3EJ90
names: Caution
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HIF1AN
gene id: 9940:HIF1AN
uniprot id: A0A6P3EQ16
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CREB3L3
gene id: 9940:CREB3L3
uniprot id: A0A6P3E5N5
uniprot id: W5PM30
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UNC45B
gene id: 9940:UNC45B
uniprot id: A0A836CYD2
names: Caution
names: Subcellular Location Annotation
messages: A band
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Z line
messages: perinuclear region

9940:MMP12
gene id: 9940:MMP12
uniprot id: W5P4C9
names: Similarity
messages: Belongs to the peptidase M10A family.

9940:DDB2
gene id: 9940:DDB2
uniprot id: W5P607
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Nucleus

9940:STAC3
gene id: 9940:STAC3
uniprot id: W5PAY0
names: Subcellular Location Annotation
messages: sarcolemma

9940:ACP3
gene id: 9940:ACP3
uniprot id: A0A6P3E5A6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COTL1
gene id: 9940:COTL1
uniprot id: A0A6P3E9I3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNA2
gene id: 9940:DNA2
uniprot id: W5P4U8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Mitochondrion
messages: Nucleus

9940:C11H17orf67
gene id: 9940:C11H17orf67
uniprot id: A0A836A848
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFT2D2
gene id: 9940:SFT2D2
uniprot id: W5PSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

9940:CD4
gene id: 9940:CD4
uniprot id: A0A6P3CX46
uniprot id: A0A6P7DSB8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:F2
gene id: 9940:F2
uniprot id: C8BKD1
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

9940:SCG2
gene id: 9940:SCG2
uniprot id: W5QEU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

9940:LOC101119483
gene id: 9940:LOC101119483
uniprot id: W5NWW7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:EIF4EBP1
gene id: 9940:EIF4EBP1
uniprot id: A0A6P3EMK6
names: Caution
names: Similarity
messages: Belongs to the eIF4E-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114303
gene id: 9940:LOC101114303
uniprot id: A0A6P3ECZ0
uniprot id: W5Q739
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC30A2
gene id: 9940:SLC30A2
uniprot id: W5P641
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9940:IL12A
gene id: 9940:IL12A
uniprot id: A0A836D852
uniprot id: Q9TU27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimer with IL12B; disulfide-linked. This heterodimer is known as interleukin IL-12 (PubMed:11023671). Heterodimer with EBI3/IL27B; not disulfide-linked. This heterodimer is known as interleukin IL-35. Interacts with NBR1; this interaction promotes IL-12 secretion (By similarity).
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes (By similarity). As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine (By similarity). Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites (By similarity).
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCOA5
gene id: 9940:NCOA5
uniprot id: A0A6P3EF56
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112491
gene id: 9940:LOC101112491
uniprot id: W5Q701
names: Similarity
messages: Belongs to the HINT family.

9940:ACTA2
gene id: 9940:ACTA2
uniprot id: A0A835ZL29
uniprot id: W5PZK7
names: Caution
names: Similarity
messages: Belongs to the actin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCOA7
gene id: 9940:NCOA7
uniprot id: W5PDE7
names: Similarity
messages: Belongs to the OXR1 family.

9940:GFRA3
gene id: 9940:GFRA3
uniprot id: W5Q3I4
names: Similarity
messages: Belongs to the GDNFR family.

9940:FETUB
gene id: 9940:FETUB
uniprot id: A0A6P3E512
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAAR5
gene id: 9940:TAAR5
uniprot id: W5NWU2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:AWAT1
gene id: 9940:AWAT1
uniprot id: A0A6P3EMZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS6KA3
gene id: 9940:RPS6KA3
uniprot id: A0A6P7DJM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
messages: Cytoplasm

9940:NT5C3A
gene id: 9940:NT5C3A
uniprot id: A0A6P3E4U5
uniprot id: A0A6P3ED16
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BCL2L1
gene id: 9940:BCL2L1
uniprot id: A0A6P3TJ46
uniprot id: Q9MZS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

9940:LRRTM4
gene id: 9940:LRRTM4
uniprot id: A0A6P3YGM1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMARCAD1
gene id: 9940:SMARCAD1
uniprot id: A0A6P3TMY1
names: Subcellular Location Annotation
messages: Chromosome

9940:GLA
gene id: 9940:GLA
uniprot id: W5NU86
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9940:PIH1D1
gene id: 9940:PIH1D1
uniprot id: A0A835ZTX5
uniprot id: W5PU56
names: Caution
names: Similarity
messages: Belongs to the PIH1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFNGR1
gene id: 9940:IFNGR1
uniprot id: W5NQS7
names: Similarity
messages: Belongs to the type II cytokine receptor family.

9940:SLC6A15
gene id: 9940:SLC6A15
uniprot id: W5Q154
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

9940:TRIM55
gene id: 9940:TRIM55
uniprot id: A0A6P3EG97
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CAPG
gene id: 9940:CAPG
uniprot id: A0A6P3E766
uniprot id: A0A6P3TIX1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
messages: Cytoplasm
messages: Melanosome
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: lamellipodium
messages: ruffle

9940:DPY19L2
gene id: 9940:DPY19L2
uniprot id: W5P5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9940:KIF5B
gene id: 9940:KIF5B
uniprot id: A0A6P3EIL9
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAB21L2
gene id: 9940:MAB21L2
uniprot id: W5Q0D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

9940:TMX2
gene id: 9940:TMX2
uniprot id: W5PL25
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum and mitochondria-associated protein that probably functions as a regulator of cellular redox state and thereby regulates protein post-translational modification, protein folding and mitochondrial activity. Indirectly regulates neuronal proliferation, migration, and organization in the developing brain.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

9940:RPS11
gene id: 9940:RPS11
uniprot id: A0A6P3EFU8
uniprot id: W5PUK3
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NUTF2
gene id: 9940:NUTF2
uniprot id: A0A6P3E9M6
uniprot id: A0A6P7ER66
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM26
gene id: 9940:TMEM26
uniprot id: A0A6P3ERY6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC52A2
gene id: 9940:SLC52A2
uniprot id: W5PWJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

9940:STMN3
gene id: 9940:STMN3
uniprot id: W5PLK2
names: Function
names: Similarity
messages: Belongs to the stathmin family.
messages: Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.

9940:UGP2
gene id: 9940:UGP2
uniprot id: A0A6P3TIW1
uniprot id: W5QFN9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

9940:NRDC
gene id: 9940:NRDC
uniprot id: A0A6P3DYR9
uniprot id: W5P4B3
names: Caution
names: Similarity
messages: Belongs to the peptidase M16 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A6
gene id: 9940:SLC25A6
uniprot id: A0A6P3CX08
uniprot id: B2MVX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCF2
gene id: 9940:NCF2
uniprot id: W5NUE1
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9940:IFNG
gene id: 9940:IFNG
uniprot id: P17773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the type II (or gamma) interferon family.
messages: Homodimer. Interacts with IFNGR1 (via extracellular domain); this interaction promotes IFNGR1 dimerization.
messages: Released primarily from activated T lymphocytes.
messages: Secreted
messages: Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activation, nuclear translocation and transcription of IFNG-regulated genes. Many of the induced genes are transcription factors such as IRF1 that are able to further drive regulation of a next wave of transcription. Plays a role in class I antigen presentation pathway by inducing a replacement of catalytic proteasome subunits with immunoproteasome subunits. In turn, increases the quantity, quality, and repertoire of peptides for class I MHC loading. Increases the efficiency of peptide generation also by inducing the expression of activator PA28 that associates with the proteasome and alters its proteolytic cleavage preference. Up-regulates as well MHC II complexes on the cell surface by promoting expression of several key molecules such as cathepsins B/CTSB, H/CTSH, and L/CTSL (By similarity). Participates in the regulation of hematopoietic stem cells during development and under homeostatic conditions by affecting their development, quiescence, and differentiation (By similarity).

9940:LPAR1
gene id: 9940:LPAR1
uniprot id: A0A6P3T7Z6
uniprot id: A0A6P7DLP5
uniprot id: P46628
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Detected in brain cortex and in pituitary pars tuberalis.
messages: Endosome
messages: Interacts with RALA and GRK2 (By similarity). Interacts with GNAQ and GNA13. Interacts with CD14; the interaction is enhanced by exposure to bacterial lipopolysaccharide (LPS) (By similarity).
messages: Membrane
messages: N-glycosylated.
messages: Receptor for lysophosphatidic acid (LPA). Plays a role in the reorganization of the actin cytoskeleton, cell migration, differentiation and proliferation, and thereby contributes to the responses to tissue damage and infectious agents. Activates downstream signaling cascades via the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Signaling inhibits adenylyl cyclase activity and decreases cellular cAMP levels. Signaling triggers an increase of cytoplasmic Ca(2+) levels. Activates RALA; this leads to the activation of phospholipase C (PLC) and the formation of inositol 1,4,5-trisphosphate. Signaling mediates activation of down-stream MAP kinases. Contributes to the regulation of cell shape. Promotes Rho-dependent reorganization of the actin cytoskeleton in neuronal cells and neurite retraction. Promotes the activation of Rho and the formation of actin stress fibers. Promotes formation of lamellipodia at the leading edge of migrating cells via activation of RAC1. Through its function as lysophosphatidic acid receptor, plays a role in chemotaxis and cell migration, including responses to injury and wounding. Plays a role in triggering inflammation in response to bacterial lipopolysaccharide (LPS) via its interaction with CD14. Promotes cell proliferation in response to lysophosphatidic acid. Required for normal skeleton development. May play a role in osteoblast differentiation. Required for normal brain development. Required for normal proliferation, survival and maturation of newly formed neurons in the adult dentate gyrus. Plays a role in pain perception and in the initiation of neuropathic pain.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101121518
gene id: 9940:LOC101121518
uniprot id: A0A836ADC0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SAP18
gene id: 9940:SAP18
uniprot id: A0A6P3ECM1
uniprot id: W5PW79
names: Caution
names: Similarity
messages: Belongs to the SAP18 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EDA2R
gene id: 9940:EDA2R
uniprot id: W5PYF3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:RGS5
gene id: 9940:RGS5
uniprot id: A0A836AEA6
uniprot id: W5PN81
names: Caution
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113683
gene id: 9940:LOC101113683
uniprot id: W5NR34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

9940:LOC101107675
gene id: 9940:LOC101107675
uniprot id: W5PID3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9940:SLC16A10
gene id: 9940:SLC16A10
uniprot id: W5PJH1
names: Subcellular Location Annotation
messages: Membrane

9940:FABP9
gene id: 9940:FABP9
uniprot id: A0A6P3ECB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POU3F4
gene id: 9940:POU3F4
uniprot id: W5P873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9940:ZNF184
gene id: 9940:ZNF184
uniprot id: A0A6P3YP14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZBTB33
gene id: 9940:ZBTB33
uniprot id: A0A6P3EN77
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PMPCB
gene id: 9940:PMPCB
uniprot id: W5QCC2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

9940:FH
gene id: 9940:FH
uniprot id: C5IWV1
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

9940:LOC101122736
gene id: 9940:LOC101122736
uniprot id: W5Q193
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TSTD1
gene id: 9940:TSTD1
uniprot id: A0A6P3E7G1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATF4
gene id: 9940:ATF4
uniprot id: A0A6P3TNM7
uniprot id: B6Z9S5
uniprot id: W5Q5M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9940:MRPL45
gene id: 9940:MRPL45
uniprot id: A0A6P3E832
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SAC3D1
gene id: 9940:SAC3D1
uniprot id: A0A835ZPJ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNC
gene id: 9940:CCNC
uniprot id: W5PQC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

9940:LEPR
gene id: 9940:LEPR
uniprot id: Q863E2
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9940:CNMD
gene id: 9940:CNMD
uniprot id: W5PA21
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9940:HSD3B1
gene id: 9940:HSD3B1
uniprot id: A0A6P3CX54
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9940:MRPL42
gene id: 9940:MRPL42
uniprot id: A0A6P3E7I7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLE1
gene id: 9940:GLE1
uniprot id: W5PJT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: Required for the export of mRNAs containing poly(A) tails from the nucleus into the cytoplasm. May be involved in the terminal step of the mRNA transport through the nuclear pore complex (NPC).
messages: nuclear pore complex

9940:GSPT1
gene id: 9940:GSPT1
uniprot id: W5PAZ2
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

9940:DBNL
gene id: 9940:DBNL
uniprot id: A0A835ZPK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABP1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Golgi apparatus membrane
messages: Perikaryon
messages: Postsynaptic density
messages: Synapse
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cell cortex
messages: clathrin-coated vesicle membrane
messages: cytoskeleton
messages: dendrite
messages: lamellipodium
messages: neuron projection
messages: podosome
messages: ruffle

9940:HDHD2
gene id: 9940:HDHD2
uniprot id: A0A6P3TG72
uniprot id: A0A6P7DD92
names: Caution
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STARD5
gene id: 9940:STARD5
uniprot id: A0A6P3EMM7
uniprot id: W5Q2J7
names: Caution
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN9
gene id: 9940:CLDN9
uniprot id: A0A6P3T5M3
uniprot id: W5PLN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:TMEM106C
gene id: 9940:TMEM106C
uniprot id: A0A836AAJ2
uniprot id: W5QDL2
names: Caution
names: Similarity
messages: Belongs to the TMEM106 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RING1
gene id: 9940:RING1
uniprot id: W5PGH8
names: Function
names: Subcellular Location Annotation
messages: Constitutes one of the E3 ubiquitin-protein ligases that mediate monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in X chromosome inactivation of female mammals. Essential component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. Compared to RNF2/RING2, it does not have the main E3 ubiquitin ligase activity on histone H2A, and it may rather act as a modulator of RNF2/RING2 activity.
messages: Nucleus speckle

9940:AGAP2
gene id: 9940:AGAP2
uniprot id: W5P5Y0
names: Similarity
messages: Belongs to the centaurin gamma-like family.

9940:PPIE
gene id: 9940:PPIE
uniprot id: A0A6P9FQL1
uniprot id: C5IWT5
uniprot id: W5QFW0
names: Caution
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.
messages: Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLRX5
gene id: 9940:GLRX5
uniprot id: A0A6P7DDU1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARNTL
gene id: 9940:ARNTL
uniprot id: A0A6P3T8T7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111505
gene id: 9940:LOC101111505
uniprot id: W5PEB3
names: Caution
names: Similarity
messages: Belongs to the spermadhesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LOC101105439
gene id: 9940:LOC101105439
uniprot id: A0A836CUQ7
uniprot id: W5PBY9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDE6H
gene id: 9940:PDE6H
uniprot id: A0A6P3YI58
uniprot id: W5QHN4
names: Function
names: Similarity
messages: Belongs to the rod/cone cGMP-PDE gamma subunit family.
messages: Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G-protein-mediated phototransduction in vertebrate rods and cones.

9940:GSK3B
gene id: 9940:GSK3B
uniprot id: A0A6P9FQG8
uniprot id: B3FL75
uniprot id: W5QEZ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPLX4
gene id: 9940:CPLX4
uniprot id: A0A6P3EQJ3
uniprot id: W5P6R1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115731
gene id: 9940:LOC101115731
uniprot id: A0A836CUR6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SGMS2
gene id: 9940:SGMS2
uniprot id: A0A6P3E6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

9940:TLR6
gene id: 9940:TLR6
uniprot id: B5DC91
uniprot id: W5NQX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:INSL3
gene id: 9940:INSL3
uniprot id: A0A6P3CWL3
uniprot id: Q4TUB8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DYNLT5
gene id: 9940:DYNLT5
uniprot id: W5PM05
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9940:CACUL1
gene id: 9940:CACUL1
uniprot id: W5NQ47
names: Similarity
messages: Belongs to the cullin family.

9940:LOC101122398
gene id: 9940:LOC101122398
uniprot id: A0A6P3E715
uniprot id: W5PUF2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNASE6
gene id: 9940:RNASE6
uniprot id: W5PT72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:LOC101103439
gene id: 9940:LOC101103439
uniprot id: W5NTY6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:HPRT1
gene id: 9940:HPRT1
uniprot id: A0A6P3YQN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115952
gene id: 9940:LOC101115952
uniprot id: W5Q993
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:C5AR1
gene id: 9940:C5AR1
uniprot id: W5PMX5
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:SLIT2
gene id: 9940:SLIT2
uniprot id: A0A6P3E6S2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LONP2
gene id: 9940:LONP2
uniprot id: A0A6P3EC56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDNF
gene id: 9940:CDNF
uniprot id: W5PAF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

9940:DDX18
gene id: 9940:DDX18
uniprot id: W5PR35
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

9940:CYSLTR2
gene id: 9940:CYSLTR2
uniprot id: A0A6P3TQR8
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZC2HC1C
gene id: 9940:ZC2HC1C
uniprot id: W5NU89
names: Similarity
messages: Belongs to the ZC2HC1 family.

9940:LOC101116245
gene id: 9940:LOC101116245
uniprot id: A0A836CXA8
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117181
gene id: 9940:LOC101117181
uniprot id: A0A6P3DZL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9940:NUBP1
gene id: 9940:NUBP1
uniprot id: A0A6P3EG89
uniprot id: W5P7E1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Cell projection
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Implicated in the regulation of centrosome duplication.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains. Interacts with KIFC1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105840
gene id: 9940:LOC101105840
uniprot id: A0A6P3EBN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OTC
gene id: 9940:OTC
uniprot id: P84010
names: Activity Regulation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-89 negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline (PubMed:14527149). The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion (Probable).
messages: Homotrimer.
messages: Mitochondrion matrix
messages: Negatively regulated by lysine acetylation.
messages: Residues 88-96, 111-125 and 247-283 form flexible loops whose positions are affected on substrate binding.

9940:UBE2J2
gene id: 9940:UBE2J2
uniprot id: A0A6P7EMN0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111906
gene id: 9940:LOC101111906
uniprot id: W5P3C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9940:PPP4R2
gene id: 9940:PPP4R2
uniprot id: A0A6P3YRM8
uniprot id: W5PI71
names: Caution
names: Similarity
messages: Belongs to the PPP4R2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SOD3
gene id: 9940:SOD3
uniprot id: W5NQP5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Nucleus

9940:MTSS1
gene id: 9940:MTSS1
uniprot id: A0A6P3EHC5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:USP3
gene id: 9940:USP3
uniprot id: W5QHY4
uniprot id: W5QHY5
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9940:XPO7
gene id: 9940:XPO7
uniprot id: W5PLR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9940:ELOF1
gene id: 9940:ELOF1
uniprot id: A0A6P3TNG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

9940:LOC101109212
gene id: 9940:LOC101109212
uniprot id: W5P3J0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

9940:ADAM17
gene id: 9940:ADAM17
uniprot id: A0A6P3E2F7
uniprot id: W5Q0N8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PABIR1
gene id: 9940:PABIR1
uniprot id: W5PF56
names: Similarity
messages: Belongs to the FAM122 family.

9940:ABCG5
gene id: 9940:ABCG5
uniprot id: W5P9W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9940:SFXN3
gene id: 9940:SFXN3
uniprot id: A0A6P7DBE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9940:HTR1A
gene id: 9940:HTR1A
uniprot id: A0A6P3YN36
uniprot id: W5P5K8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: dendrite

9940:SPATA6
gene id: 9940:SPATA6
uniprot id: W5P1E5
names: Similarity
messages: Belongs to the SPATA6 family.

9940:EDC3
gene id: 9940:EDC3
uniprot id: A0A835ZWJ4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAPK6
gene id: 9940:MAPK6
uniprot id: A0A6P3TFU3
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9940:LOC101106734
gene id: 9940:LOC101106734
uniprot id: A0A6P3E059
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BBS7
gene id: 9940:BBS7
uniprot id: A0A6P3EDI5
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

9940:RETSAT
gene id: 9940:RETSAT
uniprot id: A0A836AJL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HIGD2A
gene id: 9940:HIGD2A
uniprot id: A0A6P3EDU7
uniprot id: W5NVU5
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAP2B
gene id: 9940:RAP2B
uniprot id: W5Q0M7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Palmitoylated.
messages: Recycling endosome membrane
messages: Small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form.

9940:FXYD1
gene id: 9940:FXYD1
uniprot id: W5P3P0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone.
messages: Belongs to the FXYD family.
messages: Homotetramer. Monomer. Regulatory subunit of the sodium/potassium-transporting ATPase (NKA) which is composed of a catalytic alpha subunit, a non-catalytic beta subunit and an additional regulatory subunit. The monomeric form associates with NKA while the oligomeric form does not. Interacts with the catalytic alpha-1 subunit ATP1A1. Also interacts with the catalytic alpha-2 and alpha-3 subunits ATP1A2 and ATP1A3. Very little interaction with ATP1A1, ATP1A2 or ATP1A3 when phosphorylated at Ser-83. Interacts with the non-catalytic beta-1 subunit ATP1B1. Oxidative stress decreases interaction with ATP1A1 but increases interaction with ATP1B1.
messages: Major plasma membrane substrate for cAMP-dependent protein kinase (PKA) and protein kinase C (PKC) in several different tissues. Phosphorylated in response to insulin and adrenergic stimulation. Phosphorylation at Ser-88 stimulates sodium/potassium-transporting ATPase activity while the unphosphorylated form inhibits sodium/potassium-transporting ATPase activity. Phosphorylation increases tetramerization, decreases binding to ATP1A1 and reduces inhibition of ATP1A1 activity. Phosphorylation at Ser-83 leads to greatly reduced interaction with ATP1A1, ATP1A2 and ATP1A3. May be phosphorylated by DMPK.
messages: Palmitoylation increases half-life and stability and is enhanced upon phosphorylation at Ser-88 by PKA.
messages: T-tubule
messages: The cytoplasmic domain is sufficient to regulate sodium/potassium-transporting ATPase activity.
messages: caveola
messages: sarcolemma

9940:DRD1
gene id: 9940:DRD1
uniprot id: W5PPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
messages: Membrane
messages: dendritic spine

9940:RNF114
gene id: 9940:RNF114
uniprot id: A0A6P3EF62
uniprot id: W5PUG0
names: Caution
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BLVRA
gene id: 9940:BLVRA
uniprot id: W5Q633
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

9940:EXOG
gene id: 9940:EXOG
uniprot id: W5NTM1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9940:SHBG
gene id: 9940:SHBG
uniprot id: A0A6P7EHR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:GFOD1
gene id: 9940:GFOD1
uniprot id: W5PVV6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

9940:ACVR2A
gene id: 9940:ACVR2A
uniprot id: Q28560
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Interacts with AIP1. Part of a complex consisting of AIP1, ACVR2A, ACVR1B and SMAD3 (By similarity). Interacts with type I receptor ACVR1 (By similarity).
messages: Membrane
messages: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. Mediates induction of adipogenesis by GDF6.

9940:MISP3
gene id: 9940:MISP3
uniprot id: A0A6P3YLB5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM86A
gene id: 9940:TMEM86A
uniprot id: W5PHV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

9940:PGAM2
gene id: 9940:PGAM2
uniprot id: A0A835ZX50
names: Caution
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MFSD14A
gene id: 9940:MFSD14A
uniprot id: W5Q8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9940:LOC101115694
gene id: 9940:LOC101115694
uniprot id: A0A6P3EB29
uniprot id: W5PC47
names: Caution
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STAT3
gene id: 9940:STAT3
uniprot id: W5NTT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9940:TMEM184B
gene id: 9940:TMEM184B
uniprot id: A0A836D5P4
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP5F1D
gene id: 9940:ATP5F1D
uniprot id: A0A8N7XJE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase epsilon chain family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDHX
gene id: 9940:PDHX
uniprot id: W5QBN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

9940:DNAJC21
gene id: 9940:DNAJC21
uniprot id: A0A836CVM3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WASHC3
gene id: 9940:WASHC3
uniprot id: A0A6P3EC09
names: Caution
names: Similarity
messages: Belongs to the CCDC53 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OXT
gene id: 9940:OXT
uniprot id: P13389
names: Function
names: Similarity
names: Subunit
messages: Belongs to the vasopressin/oxytocin family.
messages: Interacts with oxytocin receptor (Ki=1.5 nM) (By similarity). Interacts with vasopressin V1aR/AVPR1A (Ki=37 nM), V1bR/AVPR1B (Ki=222 nM), and V2R/AVPR2 receptors (Ki=823 nM) (By similarity).
messages: Neurophysin 1 specifically binds oxytocin.
messages: Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR) (By similarity).

9940:GPRIN3
gene id: 9940:GPRIN3
uniprot id: W5NQE9
names: Function
messages: May be involved in neurite outgrowth.

9940:C1H1orf194
gene id: 9940:C1H1orf194
uniprot id: A0A836AID1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSME3
gene id: 9940:PSME3
uniprot id: A0A6P3EDK6
uniprot id: W5P0N8
names: Caution
names: Similarity
messages: Belongs to the PA28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLB1L
gene id: 9940:GLB1L
uniprot id: A0A6P3E216
uniprot id: W5QFF0
names: Caution
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCNH
gene id: 9940:CCNH
uniprot id: A0A6P3E513
uniprot id: W5Q318
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCOLN3
gene id: 9940:MCOLN3
uniprot id: W5PXF7
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9940:TYW3
gene id: 9940:TYW3
uniprot id: W5PSH3
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

9940:GRIK3
gene id: 9940:GRIK3
uniprot id: W5QER0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9940:MAPRE3
gene id: 9940:MAPRE3
uniprot id: W5QCK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

9940:HKDC1
gene id: 9940:HKDC1
uniprot id: W5P5V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9940:MTMR10
gene id: 9940:MTMR10
uniprot id: W5Q3Q8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9940:ADH1C
gene id: 9940:ADH1C
uniprot id: A0A6P3EDU1
names: Caution
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPB1
gene id: 9940:CPB1
uniprot id: A0A6P3DZZ9
uniprot id: W5P5L0
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RFT1
gene id: 9940:RFT1
uniprot id: W5NQD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: May be involved in N-linked oligosaccharide assembly.
messages: Membrane

9940:TP-1
gene id: 9940:TP-1
uniprot id: P56828
names: Developmental Stage
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Constitutively and exclusively expressed in the mononuclear cells of the extraembryonic trophectoderm.
messages: IFN-tau genes are intronless. They evolved from IFN-omega genes in the ruminantia suborder and have continued to duplicate independently in different lineages of the ruminantia. They code for proteins very similar in sequence but with different biological potency and pattern of expression.
messages: Major secretory product synthesized by the sheep conceptus between days 13 and 21 of pregnancy.
messages: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
messages: Secreted

9940:AASS
gene id: 9940:AASS
uniprot id: W5QB58
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

9940:MGST1
gene id: 9940:MGST1
uniprot id: A0A6P3EC95
uniprot id: A0A6P7DXS7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS25
gene id: 9940:RPS25
uniprot id: A0A6P7D1J1
uniprot id: Q6Q311
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDP1
gene id: 9940:PDP1
uniprot id: A0A6P3YKP0
uniprot id: A0A6P3YN27
uniprot id: W5PEE7
names: Caution
names: Similarity
messages: Belongs to the PP2C family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPF3
gene id: 9940:PRPF3
uniprot id: A0A6P3TF43
uniprot id: A0A6P3TQ60
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC39A7
gene id: 9940:SLC39A7
uniprot id: A0A835ZV02
uniprot id: C7BDW5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF215
gene id: 9940:ZNF215
uniprot id: A0A6P3EKH5
uniprot id: W5Q4D2
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NR1I3
gene id: 9940:NR1I3
uniprot id: W5PJR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9940:SPATS1
gene id: 9940:SPATS1
uniprot id: A0A6P3T7W2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IGBP1
gene id: 9940:IGBP1
uniprot id: A0A6P3ES16
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE2Q2
gene id: 9940:UBE2Q2
uniprot id: A0A836CWN2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BRAF
gene id: 9940:BRAF
uniprot id: W5PVT2
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9940:NDN
gene id: 9940:NDN
uniprot id: A0A6P3EE67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C18H15orf40
gene id: 9940:C18H15orf40
uniprot id: W5PX33
names: Similarity
messages: Belongs to the UPF0235 family.

9940:LOC101120889
gene id: 9940:LOC101120889
uniprot id: A0A6P7DI25
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

9940:PHAX
gene id: 9940:PHAX
uniprot id: A0A6P3EDS9
uniprot id: W5Q9Z8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TUBGCP4
gene id: 9940:TUBGCP4
uniprot id: W5PJU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9940:CAMK2D
gene id: 9940:CAMK2D
uniprot id: W5QAM4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9940:GPR18
gene id: 9940:GPR18
uniprot id: W5Q6X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

9940:LOC101102001
gene id: 9940:LOC101102001
uniprot id: A0A836CXP0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109940
gene id: 9940:LOC101109940
uniprot id: W5NR20
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

9940:ZNF496
gene id: 9940:ZNF496
uniprot id: A0A6P7E3Z2
names: Subcellular Location Annotation
messages: Nucleus

9940:GPR65
gene id: 9940:GPR65
uniprot id: A0A6P3E841
uniprot id: W5Q814
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UGT2B7
gene id: 9940:UGT2B7
uniprot id: F1CGV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:RPAIN
gene id: 9940:RPAIN
uniprot id: A0A6P3ED20
uniprot id: W5P029
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3GL
gene id: 9940:POLR3GL
uniprot id: A0A6P3TN70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9940:TMEM63A
gene id: 9940:TMEM63A
uniprot id: W5Q829
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9940:PYM1
gene id: 9940:PYM1
uniprot id: W5PMG4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pym family.
messages: Cytoplasm
messages: Interacts (via N-terminus) with magoh and rbm8a; the interaction is direct. Associates (eIF2A-like region) with the 40S ribosomal subunit and the 48S preinitiation complex.

9940:PSEN1
gene id: 9940:PSEN1
uniprot id: A0A6P3TPH6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

9940:LOC101109039
gene id: 9940:LOC101109039
uniprot id: W5P8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC443035
gene id: 9940:LOC443035
uniprot id: O97965
names: Function
names: Subcellular Location Annotation
messages: Chromosome
messages: Involved in nuclear basic protein transition: histones are replaced by spermatid specific proteins which are themselves replaced by protamines in late spermatids.
messages: Nucleus

9940:MRPL2
gene id: 9940:MRPL2
uniprot id: A0A6P3EET4
uniprot id: W5P5T0
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119384
gene id: 9940:LOC101119384
uniprot id: A0A6P3EC36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KBTBD3
gene id: 9940:KBTBD3
uniprot id: A0A6P3EA33
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRISP3
gene id: 9940:CRISP3
uniprot id: D6PX64
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:GRSF1
gene id: 9940:GRSF1
uniprot id: A0A6P3E5K6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TECRL
gene id: 9940:TECRL
uniprot id: W5P809
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

9940:ELAVL4
gene id: 9940:ELAVL4
uniprot id: W5P2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

9940:KCNH5
gene id: 9940:KCNH5
uniprot id: W5QJ21
names: Subcellular Location Annotation
messages: Membrane

9940:PLEK
gene id: 9940:PLEK
uniprot id: A0A6P3EAU7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CALHM5
gene id: 9940:CALHM5
uniprot id: A0A6P3TPS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9940:ALDOB
gene id: 9940:ALDOB
uniprot id: P52210
uniprot id: W5PCA0
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I fructose-bisphosphate aldolase family.
messages: Homotetramer. Interacts with BBS1, BBS2, BBS4 and BBS7.
messages: In vertebrates, 3 forms of this ubiquitous glycolytic enzyme are found, aldolase A in muscle, aldolase B in liver and aldolase C in brain.
messages: centriolar satellite

9940:DYA
gene id: 9940:DYA
uniprot id: Q708G2
names: Similarity
messages: Belongs to the MHC class II family.

9940:KLHL21
gene id: 9940:KLHL21
uniprot id: W5PNZ2
names: Subcellular Location Annotation
messages: spindle

9940:FUT8
gene id: 9940:FUT8
uniprot id: A0A6P3TR44
uniprot id: A0A6P3YK89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPY
gene id: 9940:NPY
uniprot id: P14765
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the NPY family.
messages: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.
messages: One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.
messages: Secreted
messages: The neuropeptide Y form is cleaved at Pro-30 by the prolyl endopeptidase FAP (seprase) activity (in vitro).
messages: neuronal dense core vesicle

9940:TDP1
gene id: 9940:TDP1
uniprot id: A0A6P3TRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

9940:SLC25A33
gene id: 9940:SLC25A33
uniprot id: B2MVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:TMEM14A
gene id: 9940:TMEM14A
uniprot id: A0A6P3EJ96
uniprot id: A0A6P7D9V6
names: Caution
names: Similarity
messages: Belongs to the TMEM14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CTC1
gene id: 9940:CTC1
uniprot id: W5QCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTC1 family.
messages: Nucleus
messages: telomere

9940:CLDN4
gene id: 9940:CLDN4
uniprot id: A0A6P3CX64
uniprot id: D6R6U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:CCT6A
gene id: 9940:CCT6A
uniprot id: W5PJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9940:SLC26A7
gene id: 9940:SLC26A7
uniprot id: W5PIL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9940:MICOS13
gene id: 9940:MICOS13
uniprot id: W5PCE9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic13 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

9940:LOC101121643
gene id: 9940:LOC101121643
uniprot id: A0A6P3DYW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110417
gene id: 9940:LOC101110417
uniprot id: W5NUU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:CSF2
gene id: 9940:CSF2
uniprot id: P28773
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GM-CSF family.
messages: Cytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
messages: Monomer. The signaling GM-CSF receptor complex is a dodecamer of two head-to-head hexamers of two alpha, two beta, and two ligand subunits (By similarity).
messages: Secreted

9940:NPM3
gene id: 9940:NPM3
uniprot id: W5Q628
names: Similarity
messages: Belongs to the nucleoplasmin family.

9940:AOX1
gene id: 9940:AOX1
uniprot id: W5Q3F9
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9940:TARS1
gene id: 9940:TARS1
uniprot id: A0A6P3ENF7
uniprot id: W5PR81
names: Caution
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3F
gene id: 9940:POLR3F
uniprot id: A0A6P3TMF1
uniprot id: W5NQ69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9940:YBEY
gene id: 9940:YBEY
uniprot id: W5PUE0
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

9940:SEC13
gene id: 9940:SEC13
uniprot id: A0A6P3ECE9
uniprot id: W5PPQ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nuclear pore complex

9940:APOA4
gene id: 9940:APOA4
uniprot id: A0A6P3ECT1
names: Caution
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DBX1
gene id: 9940:DBX1
uniprot id: W5PEX0
names: Subcellular Location Annotation
messages: Nucleus

9940:RPS12
gene id: 9940:RPS12
uniprot id: A0A6P3EH34
uniprot id: A0A835ZMF4
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SKA1
gene id: 9940:SKA1
uniprot id: A0A6P3EG34
names: Caution
names: Similarity
messages: Belongs to the SKA1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TET1
gene id: 9940:TET1
uniprot id: W5P511
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TET family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Chromosome
messages: Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in epigenetic chromatin reprogramming during embryonic development.
messages: The zinc ions have a structural role.

9940:HEBP1
gene id: 9940:HEBP1
uniprot id: W5QI36
names: Similarity
messages: Belongs to the HEBP family.

9940:RNF182
gene id: 9940:RNF182
uniprot id: A0A6P3EJP0
uniprot id: A0A6P3TI93
names: Caution
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GPR101
gene id: 9940:GPR101
uniprot id: A0A6P3YQN3
uniprot id: W5PIA8
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDE6C
gene id: 9940:PDE6C
uniprot id: W5NZF9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9940:CYM
gene id: 9940:CYM
uniprot id: P18276
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase A1 family.
messages: Chymosin is synthesized in the mucosa of the stomach. The enzyme hydrolyzes casein to paracasein.
messages: Monomer.

9940:CTXN3
gene id: 9940:CTXN3
uniprot id: A0A6P3YJB6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BBOX1
gene id: 9940:BBOX1
uniprot id: A0A6P3EMJ0
uniprot id: A0A6P7F038
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF5B
gene id: 9940:EIF5B
uniprot id: A0A836A7D6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAH
gene id: 9940:PAH
uniprot id: A0A6P3E820
uniprot id: W5Q2V2
names: Caution
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NCOA1
gene id: 9940:NCOA1
uniprot id: A0A6P3TKJ4
uniprot id: A0A6P3TNZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9940:LCMT1
gene id: 9940:LCMT1
uniprot id: A0A6P3ELN5
uniprot id: W5QAQ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPS18A
gene id: 9940:MRPS18A
uniprot id: A0A6P3ECK7
uniprot id: W5PEL4
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DKKL1
gene id: 9940:DKKL1
uniprot id: A0A6P3TUR4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTPAL
gene id: 9940:TTPAL
uniprot id: A0A6P3EJ27
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCU
gene id: 9940:MCU
uniprot id: W5PBG4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

9940:LOC101123167
gene id: 9940:LOC101123167
uniprot id: A0A6P3DZ13
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DQA
gene id: 9940:DQA
uniprot id: W1IAM8
names: Similarity
messages: Belongs to the MHC class II family.

9940:ROMO1
gene id: 9940:ROMO1
uniprot id: A0A6P3TMR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9940:OXTR
gene id: 9940:OXTR
uniprot id: Q9BDP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

9940:BRK1
gene id: 9940:BRK1
uniprot id: A0A6P3EIK7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:KCNAB1
gene id: 9940:KCNAB1
uniprot id: W5NYG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9940:GEMIN2
gene id: 9940:GEMIN2
uniprot id: A0A6P3EMT6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the gemin-2 family.
messages: Cytoplasm
messages: Part of the core SMN complex.
messages: The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105655
gene id: 9940:LOC101105655
uniprot id: W5Q5J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:KIF27
gene id: 9940:KIF27
uniprot id: W5PGS0
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9940:CCL16
gene id: 9940:CCL16
uniprot id: A0A6P3ECV3
names: Caution
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119050
gene id: 9940:LOC101119050
uniprot id: A0A6P3EAS3
uniprot id: W5QD93
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBXT
gene id: 9940:TBXT
uniprot id: A0A6P3E8V8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DGKA
gene id: 9940:DGKA
uniprot id: A0A6P3TBM7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9940:CXHXorf65
gene id: 9940:CXHXorf65
uniprot id: A0A6P3ES21
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CIAO2A
gene id: 9940:CIAO2A
uniprot id: A0A6P3E669
uniprot id: W5QHV9
names: Caution
names: Similarity
messages: Belongs to the MIP18 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM185B
gene id: 9940:TMEM185B
uniprot id: A0A836AGH0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBCA
gene id: 9940:TBCA
uniprot id: A0A6P3YMG4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

9940:XPOT
gene id: 9940:XPOT
uniprot id: A0A6P3EAN7
uniprot id: A0A6P7DWT9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

9940:SPTBN1
gene id: 9940:SPTBN1
uniprot id: A0A6P3YKN4
uniprot id: W5NZX9
names: Caution
names: Similarity
messages: Belongs to the spectrin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GON7
gene id: 9940:GON7
uniprot id: A0A6P3EBZ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DCUN1D1
gene id: 9940:DCUN1D1
uniprot id: A0A6P3YH46
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDR36
gene id: 9940:WDR36
uniprot id: A0A6P3E560
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113632
gene id: 9940:LOC101113632
uniprot id: A0A6P3ECX0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPESP1
gene id: 9940:SPESP1
uniprot id: A0A0M4AT35
uniprot id: A0A6P9FR57
names: Caution
names: Function
names: Similarity
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM59
gene id: 9940:TMEM59
uniprot id: W5PAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

9940:KEF53 p01
gene id: 9940:KEF53_p01
uniprot id: P24959
uniprot id: Q5MA65
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

9940:LOC101107947
gene id: 9940:LOC101107947
uniprot id: A0A836D4A6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBP2
gene id: 9940:RBP2
uniprot id: A0A6P3E584
uniprot id: W5PAR8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A17
gene id: 9940:SLC25A17
uniprot id: B2MVX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:ENKD1
gene id: 9940:ENKD1
uniprot id: W5NYS2
names: Subcellular Location Annotation
messages: cilium axoneme

9940:HACL1
gene id: 9940:HACL1
uniprot id: W5Q0R8
names: Similarity
messages: Belongs to the TPP enzyme family.

9940:BHLHE40
gene id: 9940:BHLHE40
uniprot id: A0A836CSN8
uniprot id: B3F209
names: Caution
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer. Heterodimer with BHLHE41/DEC2. Interacts with TCF3/E47. Interacts with ubiquitin-conjugating enzyme UBE2I/UBC9. Interacts with HDAC1, SUMO1, RXRA and BMAL1 (By similarity).
messages: Nucleus
messages: Sumoylation inhibits its ubiquitination and promotes its negative regulation of the CLOCK-BMAL1 heterodimer transcriptional activator activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1/2 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-BMAL1|BMAL2 heterodimer by competing for the binding to E-box elements (5'-CACGTG-3') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA and NR1H3/LXRA transactivation activity. May be involved in the regulation of chondrocyte differentiation via the cAMP pathway (By similarity). Represses the transcription of NR0B2 and attentuates the transactivation of NR0B2 by the CLOCK-BMAL1 complex (By similarity). Drives the circadian rhythm of blood pressure through transcriptional repression of ATP1B1 in the cardiovascular system (By similarity).
messages: Ubiquitinated; which may lead to proteasomal degradation.

9940:ACSS2
gene id: 9940:ACSS2
uniprot id: A0A836A5U9
uniprot id: W5PM93
uniprot id: W5PM94
names: Caution
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPH2
gene id: 9940:PRPH2
uniprot id: A0A6P3EES7
uniprot id: W5P133
names: Caution
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHMP4B
gene id: 9940:CHMP4B
uniprot id: A0A6P3E9A4
uniprot id: W5PGC1
names: Caution
names: Similarity
messages: Belongs to the SNF7 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKCQ
gene id: 9940:PRKCQ
uniprot id: A0A6P3TJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9940:ERC1
gene id: 9940:ERC1
uniprot id: W5PSP1
names: Subcellular Location Annotation
messages: Cytoplasm

9940:KCNJ10
gene id: 9940:KCNJ10
uniprot id: A0A6P3E670
uniprot id: W5PBW3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTPN11
gene id: 9940:PTPN11
uniprot id: A0A6P3EMB8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DEFB105B
gene id: 9940:DEFB105B
uniprot id: W5P8X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9940:RPA1
gene id: 9940:RPA1
uniprot id: A0A6P9FRE4
uniprot id: C5ISB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL5A
gene id: 9940:ARL5A
uniprot id: C5IWS8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9940:MSS51
gene id: 9940:MSS51
uniprot id: A0A6P3TA98
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120455
gene id: 9940:LOC101120455
uniprot id: A0A6P3DZG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FHL2
gene id: 9940:FHL2
uniprot id: A0A6P3E7F2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLRX2
gene id: 9940:GLRX2
uniprot id: A0A6P3E8I6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OSCP1
gene id: 9940:OSCP1
uniprot id: A0A6P3DY27
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TXNDC9
gene id: 9940:TXNDC9
uniprot id: A0A836AA03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WEE2
gene id: 9940:WEE2
uniprot id: A0A6P3EDB3
uniprot id: W5PX21
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:METTL3
gene id: 9940:METTL3
uniprot id: W5QEC3
names: Similarity
messages: Belongs to the MT-A70-like family.

9940:KCNMA1
gene id: 9940:KCNMA1
uniprot id: A0A0A7ETA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

9940:UGDH
gene id: 9940:UGDH
uniprot id: A0A6P3EAC3
uniprot id: W5PQL0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MBTD1
gene id: 9940:MBTD1
uniprot id: A0A6P3TT62
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101123417
gene id: 9940:LOC101123417
uniprot id: A0A6P3EQ38
uniprot id: W5PHK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:COPZ1
gene id: 9940:COPZ1
uniprot id: W5Q3X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

9940:ERH
gene id: 9940:ERH
uniprot id: A0A6P3EGC5
names: Caution
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM69
gene id: 9940:TMEM69
uniprot id: A0A6P3E3W6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RTCB
gene id: 9940:RTCB
uniprot id: A0A6P3E388
uniprot id: W5Q9D9
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPARG
gene id: 9940:PPARG
uniprot id: Q8HZ56
uniprot id: W5Q4M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

9940:MKNK1
gene id: 9940:MKNK1
uniprot id: A0A6P3T8V1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:LOC101116336
gene id: 9940:LOC101116336
uniprot id: W5QA37
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9940:LOC101103401
gene id: 9940:LOC101103401
uniprot id: W5NS45
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9940:LOC101118248
gene id: 9940:LOC101118248
uniprot id: W5PM66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

9940:PRIMPOL
gene id: 9940:PRIMPOL
uniprot id: A0A836CPR0
names: Caution
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLPPR1
gene id: 9940:PLPPR1
uniprot id: W5PCF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

9940:EPB41
gene id: 9940:EPB41
uniprot id: W5NX11
uniprot id: W5NX12
names: Subcellular Location Annotation
messages: Nucleus
messages: cell cortex

9940:TSSK6
gene id: 9940:TSSK6
uniprot id: A0A2R8G2P5
uniprot id: A0A6P3TLS1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:TTC9C
gene id: 9940:TTC9C
uniprot id: A0A6P3EPL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCN2
gene id: 9940:CCN2
uniprot id: C7EDS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:C26H8orf48
gene id: 9940:C26H8orf48
uniprot id: A0A836CR03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HEBP2
gene id: 9940:HEBP2
uniprot id: W5NRM2
names: Similarity
messages: Belongs to the HEBP family.

9940:SCPEP1
gene id: 9940:SCPEP1
uniprot id: W5PBM9
names: Similarity
messages: Belongs to the peptidase S10 family.

9940:MDH1
gene id: 9940:MDH1
uniprot id: W5QFQ0
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

9940:NSMCE2
gene id: 9940:NSMCE2
uniprot id: W5PEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

9940:RNF4
gene id: 9940:RNF4
uniprot id: A0A6P3YJV1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:QRFP
gene id: 9940:QRFP
uniprot id: B2KTD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFamide neuropeptide family.
messages: Secreted

9940:SRGN
gene id: 9940:SRGN
uniprot id: A0A835ZJZ8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF5A2
gene id: 9940:EIF5A2
uniprot id: A0A6P3E541
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

9940:CLPSL2
gene id: 9940:CLPSL2
uniprot id: A0A6P3EJR5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAR1
gene id: 9940:FAR1
uniprot id: W5PBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9940:DFFA
gene id: 9940:DFFA
uniprot id: A0A835ZXF7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101115567
gene id: 9940:LOC101115567
uniprot id: W5Q7C3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:XRCC4
gene id: 9940:XRCC4
uniprot id: A0A836A6L1
uniprot id: W5Q208
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XRCC4-XLF family. XRCC4 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101107687
gene id: 9940:LOC101107687
uniprot id: A0A6P3ECA6
uniprot id: W5QGA9
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TIMP1
gene id: 9940:TIMP1
uniprot id: P50122
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts with MMP1, MMP3, MMP10 and MMP13, but has only very low affinity for MMP14. Interacts with CD63; identified in a complex with CD63 and ITGB1 (By similarity).
messages: Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling (By similarity).
messages: N-glycosylated.
messages: Secreted
messages: The activity of TIMP1 is dependent on the presence of disulfide bonds.

9940:C19H3orf18
gene id: 9940:C19H3orf18
uniprot id: A0A6P3EN95
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114053
gene id: 9940:LOC101114053
uniprot id: W5PRY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:TSPYL4
gene id: 9940:TSPYL4
uniprot id: A0A6P3TRG3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9940:DUSP11
gene id: 9940:DUSP11
uniprot id: A0A836A7A1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118285
gene id: 9940:LOC101118285
uniprot id: A0A6P3EH44
uniprot id: W5PMY4
names: Caution
names: Similarity
messages: Belongs to the ATG8 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR2J
gene id: 9940:POLR2J
uniprot id: A0A6P3EGI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPRKB
gene id: 9940:TPRKB
uniprot id: A0A6P3TE34
names: Similarity
messages: Belongs to the CGI121/TPRKB family.

9940:NDUFA8
gene id: 9940:NDUFA8
uniprot id: A0A8N7XJG2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFSF13
gene id: 9940:TNFSF13
uniprot id: W5PXV6
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9940:PLAC8L1
gene id: 9940:PLAC8L1
uniprot id: W5NWE3
names: Similarity
messages: Belongs to the cornifelin family.

9940:HAO1
gene id: 9940:HAO1
uniprot id: W5NPE3
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

9940:RARB
gene id: 9940:RARB
uniprot id: W5P2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9940:BTG1
gene id: 9940:BTG1
uniprot id: B7U799
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

9940:EIF6
gene id: 9940:EIF6
uniprot id: A0A6P3TUB9
uniprot id: A0A6P9FQI1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis. Involved in miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Modulates cell cycle progression and global translation of pre-B cells, its activation seems to be rate-limiting in tumorigenesis and tumor growth.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit. Interacts with RACK1. Interacts with DICER1, AGO2, TARBP2, MOV10 and RPL7A; they form a large RNA-induced silencing complex (RISC).
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:C1S
gene id: 9940:C1S
uniprot id: A0A6P3TKJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:MCM9
gene id: 9940:MCM9
uniprot id: W5PFE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9940:LOC101116254
gene id: 9940:LOC101116254
uniprot id: W5P8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:RCAN3
gene id: 9940:RCAN3
uniprot id: W5P9D3
names: Similarity
messages: Belongs to the RCAN family.

9940:RAB20
gene id: 9940:RAB20
uniprot id: A0A6P3EI01
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARHGEF3
gene id: 9940:ARHGEF3
uniprot id: W5PZJ3
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

9940:TRIM2
gene id: 9940:TRIM2
uniprot id: W5NZD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9940:ZSCAN12
gene id: 9940:ZSCAN12
uniprot id: W5Q8N0
names: Subcellular Location Annotation
messages: Nucleus

9940:ADK
gene id: 9940:ADK
uniprot id: W5PFM8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

9940:CMTM5
gene id: 9940:CMTM5
uniprot id: W5QDF9
names: Subcellular Location Annotation
messages: Membrane

9940:C1H3orf80
gene id: 9940:C1H3orf80
uniprot id: A0A6P3DZW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZC3H12B
gene id: 9940:ZC3H12B
uniprot id: A0A6P3YPQ7
uniprot id: W5P4G0
names: Caution
names: Similarity
messages: Belongs to the ZC3H12 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IAH1
gene id: 9940:IAH1
uniprot id: W5Q0L0
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

9940:LOC101120294
gene id: 9940:LOC101120294
uniprot id: W5PB55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:FEZ1
gene id: 9940:FEZ1
uniprot id: A0A6P3EPH2
uniprot id: A0A6P3T8H1
names: Caution
names: Similarity
messages: Belongs to the zygin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DUSP10
gene id: 9940:DUSP10
uniprot id: A0A6P3E8K1
uniprot id: W5PUM4
names: Caution
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FZD3
gene id: 9940:FZD3
uniprot id: W5Q028
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:LOC101113073
gene id: 9940:LOC101113073
uniprot id: A0A6P3TU87
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPTC7
gene id: 9940:PPTC7
uniprot id: A0A835ZRL4
uniprot id: W5Q6K7
names: Caution
names: Similarity
messages: Belongs to the PP2C family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERLIN2
gene id: 9940:ERLIN2
uniprot id: W5NRD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

9940:LOC101105358
gene id: 9940:LOC101105358
uniprot id: W5P9D0
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9940:VPS41
gene id: 9940:VPS41
uniprot id: W5Q8J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

9940:NKIRAS1
gene id: 9940:NKIRAS1
uniprot id: A0A6P3YPJ4
uniprot id: A0A6P3YPZ5
names: Caution
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117748
gene id: 9940:LOC101117748
uniprot id: W5QDC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PLA1A
gene id: 9940:PLA1A
uniprot id: W5QET9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9940:TAS2R7
gene id: 9940:TAS2R7
uniprot id: W5QGH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
messages: Membrane

9940:OTUD7B
gene id: 9940:OTUD7B
uniprot id: W5QHV5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:TRAPPC4
gene id: 9940:TRAPPC4
uniprot id: A0A6P3EA87
uniprot id: W5PSI4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network

9940:ADAMTS1
gene id: 9940:ADAMTS1
uniprot id: W5PZU6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9940:SEC24C
gene id: 9940:SEC24C
uniprot id: A0A6P3ES24
uniprot id: W5PDT0
uniprot id: W5PDT3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:GMPS
gene id: 9940:GMPS
uniprot id: A0A6P3YFH9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CA11
gene id: 9940:CA11
uniprot id: A0A836CXA3
uniprot id: Q95203
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Does not have a catalytic activity.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116968
gene id: 9940:LOC101116968
uniprot id: W5PMF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9940:NRBP1
gene id: 9940:NRBP1
uniprot id: A0A6P3E9T5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN1
gene id: 9940:CLDN1
uniprot id: A0A6P3CXR7
uniprot id: D6R6U0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:SHOC2
gene id: 9940:SHOC2
uniprot id: A0A6P3ER18
uniprot id: A0A6P3TFN2
names: Caution
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102647
gene id: 9940:LOC101102647
uniprot id: W5QFE5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro.
messages: Belongs to the 7B2 family.
messages: Interacts with PCSK2/PC2 early in the secretory pathway. Dissociation occurs at later stages.
messages: Secreted

9940:FNBP1L
gene id: 9940:FNBP1L
uniprot id: A0A6P3DZ28
uniprot id: W5Q5W3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

9940:PLPPR5
gene id: 9940:PLPPR5
uniprot id: A0A6P3TCZ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LBX2
gene id: 9940:LBX2
uniprot id: A0A6P3E7E8
uniprot id: W5PT61
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GTF2B
gene id: 9940:GTF2B
uniprot id: A0A6P3E6N3
names: Caution
names: Similarity
messages: Belongs to the TFIIB family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NIF3L1
gene id: 9940:NIF3L1
uniprot id: A0A6P3TMU8
uniprot id: W5Q595
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

9940:LRRFIP2
gene id: 9940:LRRFIP2
uniprot id: W5Q4T0
names: Similarity
messages: Belongs to the LRRFIP family.

9940:GPR171
gene id: 9940:GPR171
uniprot id: W5Q178
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:ITM2B
gene id: 9940:ITM2B
uniprot id: A0A6P9FQH2
uniprot id: B3VSB9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDCA2
gene id: 9940:CDCA2
uniprot id: W5PJE5
names: Subcellular Location Annotation
messages: Nucleus

9940:GPM6B
gene id: 9940:GPM6B
uniprot id: W5PPQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9940:LOC105615767
gene id: 9940:LOC105615767
uniprot id: A0A835ZMU2
uniprot id: W5Q7R3
names: Caution
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RIBC1
gene id: 9940:RIBC1
uniprot id: W5PF55
names: Similarity
messages: Belongs to the RIB43A family.

9940:CD274
gene id: 9940:CD274
uniprot id: A0A6P3E1B8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SOD1
gene id: 9940:SOD1
uniprot id: B9VGZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Nucleus

9940:BMP4
gene id: 9940:BMP4
uniprot id: A8VTF8
uniprot id: W5QIU1
names: Similarity
messages: Belongs to the TGF-beta family.

9940:NPC2
gene id: 9940:NPC2
uniprot id: A0A6P3E6E8
uniprot id: A0A6P3TPJ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPC2 family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109790
gene id: 9940:LOC101109790
uniprot id: A0A6P3E3S9
uniprot id: W5Q9R0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STX4
gene id: 9940:STX4
uniprot id: A0A6P3T5W3
names: Similarity
messages: Belongs to the syntaxin family.

9940:GRIA3
gene id: 9940:GRIA3
uniprot id: A0A6P3TI04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9940:LOC105602384
gene id: 9940:LOC105602384
uniprot id: A0A836CV75
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102314
gene id: 9940:LOC101102314
uniprot id: A0A836D3R9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122667
gene id: 9940:LOC101122667
uniprot id: A0A6P7DQ21
uniprot id: J9UXY3
names: Caution
names: Similarity
messages: Belongs to the GroES chaperonin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113335
gene id: 9940:LOC101113335
uniprot id: A0A6P3EAV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:ARSJ
gene id: 9940:ARSJ
uniprot id: W5QA75
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9940:LOC101114379
gene id: 9940:LOC101114379
uniprot id: A0A836ABR5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120701
gene id: 9940:LOC101120701
uniprot id: W5PM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9940:MEIS1
gene id: 9940:MEIS1
uniprot id: W5QFD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

9940:PELI1
gene id: 9940:PELI1
uniprot id: A0A6P3EAV1
uniprot id: A0A6P3TAJ5
names: Caution
names: Function
names: Similarity
messages: Belongs to the pellino family.
messages: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD2
gene id: 9940:CD2
uniprot id: A0A6P3E6Y0
uniprot id: W5QG93
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRNT1
gene id: 9940:TRNT1
uniprot id: A0A6P3T2Z6
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

9940:IFT122
gene id: 9940:IFT122
uniprot id: W5PYJ7
names: Subcellular Location Annotation
messages: cilium

9940:LOC101111893
gene id: 9940:LOC101111893
uniprot id: W5P307
names: Similarity
messages: Belongs to the KRTAP type 3 family.

9940:ELP6
gene id: 9940:ELP6
uniprot id: A0A6P3THN0
uniprot id: W5P050
names: Similarity
messages: Belongs to the ELP6 family.

9940:GUCY1A1
gene id: 9940:GUCY1A1
uniprot id: A0A6P3TCV9
uniprot id: A0A6P7D151
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MIGA2
gene id: 9940:MIGA2
uniprot id: W5PGD7
names: Similarity
messages: Belongs to the mitoguardin family.

9940:LOC101120556
gene id: 9940:LOC101120556
uniprot id: A0A835ZKX6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC90B
gene id: 9940:CCDC90B
uniprot id: A0A835ZLP8
uniprot id: W5P5J9
names: Caution
names: Similarity
messages: Belongs to the CCDC90 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC6A2
gene id: 9940:SLC6A2
uniprot id: A0A6P3YQD6
uniprot id: W5Q9U1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:S100A5
gene id: 9940:S100A5
uniprot id: A0A6P3TJ05
names: Caution
names: Similarity
messages: Belongs to the S-100 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GSTM3
gene id: 9940:GSTM3
uniprot id: A0A6P3TM19
names: Similarity
messages: Belongs to the GST superfamily. Mu family.

9940:SPA17
gene id: 9940:SPA17
uniprot id: Q9TU08
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates.

9940:TTC32
gene id: 9940:TTC32
uniprot id: A0A6P3E713
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNST
gene id: 9940:CNST
uniprot id: A0A836CYD7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP2R5E
gene id: 9940:PPP2R5E
uniprot id: A0A6P3E6C5
uniprot id: A0A6P3TUR0
names: Caution
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPF2
gene id: 9940:RPF2
uniprot id: W5Q1T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

9940:CHST10
gene id: 9940:CHST10
uniprot id: W5PUZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9940:GM2A
gene id: 9940:GM2A
uniprot id: A0A836AHY7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBKS
gene id: 9940:RBKS
uniprot id: A0A6P3E270
uniprot id: W5QDU7
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114167
gene id: 9940:LOC101114167
uniprot id: W5P635
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

9940:FOXP3
gene id: 9940:FOXP3
uniprot id: B8Y745
names: Subcellular Location Annotation
messages: Nucleus

9940:CLSPN
gene id: 9940:CLSPN
uniprot id: W5QE43
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101102101
gene id: 9940:LOC101102101
uniprot id: W5Q169
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ZGPAT
gene id: 9940:ZGPAT
uniprot id: A0A836D031
uniprot id: C5IJB0
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CHD4/Mi-2; the interaction is direct.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor (By similarity).

9940:BSND
gene id: 9940:BSND
uniprot id: A0A6P3E405
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM98C
gene id: 9940:FAM98C
uniprot id: W5P6J6
names: Similarity
messages: Belongs to the FAM98 family.

9940:DCTPP1
gene id: 9940:DCTPP1
uniprot id: A0A6P3EE82
uniprot id: W5P8H4
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homotetramer.
messages: Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:LOC101116777
gene id: 9940:LOC101116777
uniprot id: A0A6P7E9I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cilium
messages: clathrin-coated vesicle membrane

9940:LOC101107296
gene id: 9940:LOC101107296
uniprot id: W5P1T6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:CASQ2
gene id: 9940:CASQ2
uniprot id: W5QG04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

9940:LALBA
gene id: 9940:LALBA
uniprot id: P09462
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lactose synthase (LS) is a heterodimer of a catalytic component, beta1,4-galactosyltransferase (beta4Gal-T1) and a regulatory component, alpha-lactalbumin (LA).
messages: Mammary gland specific. Secreted in milk.
messages: Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.
messages: Secreted

9940:LOC101116002
gene id: 9940:LOC101116002
uniprot id: W5PZL3
names: Similarity
messages: Belongs to the CLCR family.

9940:TMPRSS11A
gene id: 9940:TMPRSS11A
uniprot id: A0A6P3TPW8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFRP4
gene id: 9940:SFRP4
uniprot id: A0A6P3ECZ5
uniprot id: W5PGJ0
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TM2D3
gene id: 9940:TM2D3
uniprot id: A0A6P3T2F3
uniprot id: W5Q526
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJC2
gene id: 9940:DNAJC2
uniprot id: A0A6P3E8U1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:CALCRL
gene id: 9940:CALCRL
uniprot id: W5Q4Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9940:ADIPOR1
gene id: 9940:ADIPOR1
uniprot id: A0A6P3CYJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9940:FUNDC1
gene id: 9940:FUNDC1
uniprot id: W5P0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

9940:TFAP2A
gene id: 9940:TFAP2A
uniprot id: Q9N0N3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AP-2 family.
messages: Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members. Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I. Interacts with RALBP1 in a complex also containing EPN1 and NUMB during interphase and mitosis. Interacts with KCTD1; this interaction represses transcription activation. Interacts (via C-terminus) with CITED2 (via C-terminus); the interaction stimulates TFAP2A-transcriptional activation. Interacts (via N-terminus) with EP300 (via N-terminus); the interaction requires CITED2 (By similarity). Interacts with KCTD15; this interaction inhibits TFAP2A transcriptional activation (By similarity).
messages: Nucleus
messages: Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-alpha is the only AP-2 protein required for early morphogenesis of the lens vesicle. Together with the CITED2 coactivator, stimulates the PITX2 P1 promoter transcription activation. Associates with chromatin to the PITX2 P1 promoter region (By similarity).
messages: The PPxY motif mediates interaction with WWOX.

9940:ACOD1
gene id: 9940:ACOD1
uniprot id: W5Q396
names: Similarity
messages: Belongs to the PrpD family.

9940:DZIP3
gene id: 9940:DZIP3
uniprot id: W5QCG8
names: Subcellular Location Annotation
messages: Cytoplasm

9940:LOC101112404
gene id: 9940:LOC101112404
uniprot id: A0A097IYE5
names: Similarity
messages: Belongs to the KRTAP type 3 family.

9940:ACBD6
gene id: 9940:ACBD6
uniprot id: A0A6P3EJV4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IQCG
gene id: 9940:IQCG
uniprot id: W5QGB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC9 family.
messages: flagellum
messages: flagellum axoneme

9940:FAM183A
gene id: 9940:FAM183A
uniprot id: A0A6P3E672
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106021
gene id: 9940:LOC101106021
uniprot id: W5NZL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

9940:L3MBTL3
gene id: 9940:L3MBTL3
uniprot id: A0A6P3TPZ3
uniprot id: A0A6P3TRL8
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HS2ST1
gene id: 9940:HS2ST1
uniprot id: A0A6P3E5B6
uniprot id: W5PZV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACTL7B
gene id: 9940:ACTL7B
uniprot id: W5NYG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

9940:NLRP3
gene id: 9940:NLRP3
uniprot id: A0A836AGY9
uniprot id: W5PCI1
names: Caution
names: Similarity
messages: Belongs to the NLRP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAQR8
gene id: 9940:PAQR8
uniprot id: A0A6P3T3S0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TNFSF4
gene id: 9940:TNFSF4
uniprot id: W5PZ67
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9940:CPXM1
gene id: 9940:CPXM1
uniprot id: A0A6P3EKH6
uniprot id: W5P6M9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104027
gene id: 9940:LOC101104027
uniprot id: Q28580
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the KRTAP type 7 family.
messages: In the wool cortex, wool keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant wool shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of wool keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with wool keratins.
messages: Wool.

9940:TRAM1
gene id: 9940:TRAM1
uniprot id: A0A6P3E782
uniprot id: W5P1B6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMU1
gene id: 9940:SMU1
uniprot id: A0A6P3E7Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMSB4X
gene id: 9940:TMSB4X
uniprot id: A0A6P3TKJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9940:PARK7
gene id: 9940:PARK7
uniprot id: A0A6P3E8Q6
uniprot id: W5PK66
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAMP2
gene id: 9940:RAMP2
uniprot id: W5NZT5
names: Similarity
messages: Belongs to the RAMP family.

9940:SLC2A2
gene id: 9940:SLC2A2
uniprot id: W5QHW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

9940:LOC101107295
gene id: 9940:LOC101107295
uniprot id: A0A6P3EHJ3
uniprot id: W5P212
names: Caution
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DARS1
gene id: 9940:DARS1
uniprot id: C5IWV2
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

9940:SLC35F2
gene id: 9940:SLC35F2
uniprot id: A0A6P3ELX3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLRN3
gene id: 9940:CLRN3
uniprot id: W5PXA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

9940:POLR2G
gene id: 9940:POLR2G
uniprot id: B7TJ05
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

9940:DPY30
gene id: 9940:DPY30
uniprot id: A0A836AI52
names: Caution
names: Similarity
messages: Belongs to the dpy-30 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AMER1
gene id: 9940:AMER1
uniprot id: A0A6P3ERV9
uniprot id: W5P5V4
names: Caution
names: Similarity
messages: Belongs to the Amer family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEP19
gene id: 9940:CEP19
uniprot id: A0A6P3E7Z3
uniprot id: A0A6P3T5K7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP19 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centriole
messages: cilium basal body
messages: spindle pole

9940:TBX15
gene id: 9940:TBX15
uniprot id: W5QGN3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:PXYLP1
gene id: 9940:PXYLP1
uniprot id: A0A6P3E764
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112672
gene id: 9940:LOC101112672
uniprot id: W5PCI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101103623
gene id: 9940:LOC101103623
uniprot id: W5PFW8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Monomer.
messages: Secreted

9940:RNASE12
gene id: 9940:RNASE12
uniprot id: W5QEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:HAGH
gene id: 9940:HAGH
uniprot id: A0A6P3EE16
uniprot id: W5Q540
names: Caution
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101113616
gene id: 9940:LOC101113616
uniprot id: A0A6P3EJT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:XPO5
gene id: 9940:XPO5
uniprot id: W5PCK3
names: Subcellular Location Annotation
messages: Cytoplasm

9940:PABPC4
gene id: 9940:PABPC4
uniprot id: A0A6P7E143
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9940:HARBI1
gene id: 9940:HARBI1
uniprot id: A0A6P3EMM5
uniprot id: A0A6P3TFQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

9940:UPB1
gene id: 9940:UPB1
uniprot id: A0A6P3EMG9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102142
gene id: 9940:LOC101102142
uniprot id: W5NU82
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9940:H2AZ1
gene id: 9940:H2AZ1
uniprot id: A0A836A1Q6
uniprot id: Q6YNC8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylated on Lys-5, Lys-8, Lys-12 and Lys-14 by KAT2A; KAT2A is recruited by the XPC complex in absence of DNA damage (By similarity). Acetylated on Lys-5, Lys-8 and Lys-12 during interphase; acetylation disappears at mitosis (By similarity). Acetylation by the NuA4 histone acetyltransferase complex is required for hematopoietic stem cell maintenance (By similarity).
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Lactylated in macrophages by EP300/P300 by using lactoyl-CoA directly derived from endogenous or exogenous lactate, leading to stimulates gene transcription.
messages: Monomethylated on Lys-5 and Lys-8 by SETD6. SETD6 predominantly methylates Lys-8, lys-5 being a possible secondary site.
messages: Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression.
messages: Not phosphorylated.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA. H2A or its variant H2AZ1 forms a heterodimer with H2B. H2AZ1 interacts with INCENP. Interacts (via M6 cassette) with ANP32E; leading to removal of H2A.Z/H2AZ1 from the nucleosome. Interacts with VPS72 (via N-terminal domain); the interaction is enhanced by VPS72 phosphorylation which is promoted by ZNHIT1. Interacts with PWWP2A. Interacts with FH (when phosphorylated by PRKDC). Interacts with ZNHIT1; the interaction results in recruitment of H2AZ1 to the MYOG promoter region which is required for muscle-specific gene expression (By similarity).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity).

9940:BMT2
gene id: 9940:BMT2
uniprot id: W5NVA5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

9940:IFNT5
gene id: 9940:IFNT5
uniprot id: Q28595
names: Developmental Stage
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Constitutively and exclusively expressed in the mononuclear cells of the extraembryonic trophectoderm.
messages: IFN-tau genes are intronless. They evolved from IFN-omega genes in the ruminantia suborder and have continued to duplicate independently in different lineages of the ruminantia. They code for proteins very similar in sequence but with different biological potency and pattern of expression.
messages: Major secretory product synthesized by the sheep conceptus between days 13 and 21 of pregnancy.
messages: Paracrine hormone primarily responsible for maternal recognition of pregnancy. Interacts with endometrial receptors, probably type I interferon receptors, and blocks estrogen receptor expression, preventing the estrogen-induced increase in oxytocin receptor expression in the endometrium. This results in the suppression of the pulsatile endometrial release of the luteolytic hormone prostaglandin F2-alpha, hindering the regression of the corpus luteum (luteolysis) and therefore a return to ovarian cyclicity. This, and a possible direct effect of IFN-tau on prostaglandin synthesis, leads in turn to continued ovarian progesterone secretion, which stimulates the secretion by the endometrium of the nutrients required for the growth of the conceptus. In summary, displays particularly high antiviral and antiproliferative potency concurrently with particular weak cytotoxicity, high antiluteolytic activity and immunomodulatory properties. In contrast with other IFNs, IFN-tau is not virally inducible.
messages: Secreted

9940:LOC101120345
gene id: 9940:LOC101120345
uniprot id: A0A6P3TIH5
names: Caution
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NIP7
gene id: 9940:NIP7
uniprot id: W5P046
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

9940:LOC101116438
gene id: 9940:LOC101116438
uniprot id: A0A835ZLV4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP2R5C
gene id: 9940:PPP2R5C
uniprot id: W5NWN4
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9940:MECOM
gene id: 9940:MECOM
uniprot id: A0A836AFK1
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RBM18
gene id: 9940:RBM18
uniprot id: A0A6P3E6Z8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AKR1D1
gene id: 9940:AKR1D1
uniprot id: W5PK05
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9940:RBBP7
gene id: 9940:RBBP7
uniprot id: A0A6P3YQ28
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE2L3
gene id: 9940:UBE2L3
uniprot id: A0A6P3YRR0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:PGK2
gene id: 9940:PGK2
uniprot id: W5PG09
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

9940:PIGW
gene id: 9940:PIGW
uniprot id: A0A6P3ECU4
uniprot id: A0A6P3TSS0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119640
gene id: 9940:LOC101119640
uniprot id: A0A6P3YIF3
uniprot id: W5PJ26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PHOSPHO2
gene id: 9940:PHOSPHO2
uniprot id: A0A6P3TMJ8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

9940:ELF1
gene id: 9940:ELF1
uniprot id: W5PA85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9940:SLC25A44
gene id: 9940:SLC25A44
uniprot id: A0A6P3TRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:PDZD11
gene id: 9940:PDZD11
uniprot id: A0A6P3ESH4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL23
gene id: 9940:RPL23
uniprot id: A0A6P3TI59
uniprot id: A0A6P7EGQ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIGF
gene id: 9940:PIGF
uniprot id: A0A6P3CY21
uniprot id: K4P443
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAS1
gene id: 9940:MAS1
uniprot id: A0A6P3TVE4
uniprot id: W5NXQ6
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RICTOR
gene id: 9940:RICTOR
uniprot id: A0A6P3EDQ2
uniprot id: W5PIY2
names: Caution
names: Similarity
messages: Belongs to the RICTOR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ABHD5
gene id: 9940:ABHD5
uniprot id: A0A6P9FQC8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FOXO4
gene id: 9940:FOXO4
uniprot id: W5Q3G2
names: Subcellular Location Annotation
messages: Nucleus

9940:RBM5
gene id: 9940:RBM5
uniprot id: A0A6P3ECA8
uniprot id: W5PMN8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RBM5/RBM10 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ST6GAL1
gene id: 9940:ST6GAL1
uniprot id: H9NAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9940:MARCHF5
gene id: 9940:MARCHF5
uniprot id: A0A6P3EDK4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MPDU1
gene id: 9940:MPDU1
uniprot id: W5PZH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPDU1 (TC 2.A.43.3) family.
messages: Membrane
messages: Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.

9940:ARF5
gene id: 9940:ARF5
uniprot id: A0A6P9FQH5
uniprot id: C5IWS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB6A
gene id: 9940:RAB6A
uniprot id: A0A6P3EMG4
uniprot id: A0A836D4I9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EMP3
gene id: 9940:EMP3
uniprot id: A0A6P3EFT7
uniprot id: A0A6P3TZH5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probably involved in cell proliferation and cell-cell interactions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CORT
gene id: 9940:CORT
uniprot id: B8Y4A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

9940:SPATA24
gene id: 9940:SPATA24
uniprot id: A0A836AFT9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MORF4L2
gene id: 9940:MORF4L2
uniprot id: A0A6P3EFC6
uniprot id: A0A6P3EHK7
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK19
gene id: 9940:CDK19
uniprot id: A0A6P3EFS8
uniprot id: W5PJS1
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KPNA2
gene id: 9940:KPNA2
uniprot id: A0A6P3EDR3
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9940:TSHR
gene id: 9940:TSHR
uniprot id: P56495
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Glycosylated.
messages: Interacts with heterodimer GPHA2:GPHB5; this interaction stimulates cAMP production. Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.
messages: Sulfated. Sulfation on Tyr-385 plays a role in thyrotropin receptor binding and activation.

9940:LOC101111435
gene id: 9940:LOC101111435
uniprot id: W5PLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Secreted

9940:LOC101108324
gene id: 9940:LOC101108324
uniprot id: W5P204
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:GBE1
gene id: 9940:GBE1
uniprot id: W5Q5V0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

9940:LOC101120447
gene id: 9940:LOC101120447
uniprot id: W5QFN5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9940:COG6
gene id: 9940:COG6
uniprot id: A0A836ABC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane
messages: Required for normal Golgi function.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STK17B
gene id: 9940:STK17B
uniprot id: W5PZD3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:FAM168A
gene id: 9940:FAM168A
uniprot id: W5PD37
names: Similarity
messages: Belongs to the FAM168 family.

9940:COMMD10
gene id: 9940:COMMD10
uniprot id: A0A6P3E4N0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTC21B
gene id: 9940:TTC21B
uniprot id: A0A836D5W5
uniprot id: W5P4N3
names: Caution
names: Similarity
messages: Belongs to the TTC21 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TUBB
gene id: 9940:TUBB
uniprot id: W5PPT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9940:LRRC59
gene id: 9940:LRRC59
uniprot id: A0A6P3EA66
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEC24D
gene id: 9940:SEC24D
uniprot id: W5Q678
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9940:CTDSP2
gene id: 9940:CTDSP2
uniprot id: A0A6P3EAP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPC1L1
gene id: 9940:NPC1L1
uniprot id: W5Q1M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9940:WNT10B
gene id: 9940:WNT10B
uniprot id: W5NXT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9940:HMBS
gene id: 9940:HMBS
uniprot id: A0A6P3EG84
uniprot id: W5PTY1
names: Caution
names: Similarity
messages: Belongs to the HMBS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPF40A
gene id: 9940:PRPF40A
uniprot id: A0A6P3E1S2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PAIP2
gene id: 9940:PAIP2
uniprot id: A0A6P3E4S9
uniprot id: W5Q6C6
names: Caution
names: Similarity
messages: Belongs to the PAIP2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GMEB1
gene id: 9940:GMEB1
uniprot id: A0A6P7DR99
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KEF53 p04
gene id: 9940:KEF53_p04
uniprot id: O78755
uniprot id: Q5MA68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

9940:COQ10B
gene id: 9940:COQ10B
uniprot id: W5Q1J7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9940:PEBP4
gene id: 9940:PEBP4
uniprot id: A0A836AL70
names: Caution
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTLL9
gene id: 9940:TTLL9
uniprot id: W5NVR4
names: Similarity
messages: Belongs to the tubulin--tyrosine ligase family.

9940:LOC105607240
gene id: 9940:LOC105607240
uniprot id: W5QCN5
names: Function
names: Similarity
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.

9940:UCP1
gene id: 9940:UCP1
uniprot id: G9I8W4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: May undergo ubiquitin-mediated proteasomal degradation.
messages: Membrane
messages: Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
messages: Mitochondrion inner membrane

9940:CTNS
gene id: 9940:CTNS
uniprot id: W5Q7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cystinosin family.
messages: Membrane

9940:TIMM8B
gene id: 9940:TIMM8B
uniprot id: A0A6P3ECS0
uniprot id: W5Q3M6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

9940:POMC
gene id: 9940:POMC
uniprot id: P01191
names: Function
names: Induction
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: ACTH and MSH are produced by the pituitary gland.
messages: Anorexigenic peptide. Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Endogenous orexigenic opiate.
messages: Increases the pigmentation of skin by increasing melanin production in melanocytes.
messages: Repressed by treatment with estradiol.
messages: Secreted
messages: Specific enzymatic cleavages at paired basic residues yield the different active peptides.
messages: Stimulates the adrenal glands to release cortisol.

9940:ATOX1
gene id: 9940:ATOX1
uniprot id: Q9XT28
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATX1 family.
messages: Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity).
messages: Interacts with ATP7B (By similarity). Interacts with ATP7A (By similarity).
messages: The heavy-metal-associated domain (HMA) coordinates a Cu(+) ion via the cysteine residues within the CXXC motif. The transfer of Cu(+) ion from ATOX1 to ATP7A involves the formation of a three-coordinate Cu(+)-bridged heterodimer where the metal is shared between the two metal binding sites of ATOX1 and ATP7A. The Cu(+) ion appears to switch between two coordination modes, forming two links with one protein and one with the other. Cisplatin, a chemotherapeutic drug, can bind the CXXC motif and hinder the release of Cu(+) ion.

9940:MTCP1
gene id: 9940:MTCP1
uniprot id: A0A6P3TB53
uniprot id: W5P008
names: Caution
names: Similarity
messages: Belongs to the TCL1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDCL3
gene id: 9940:PDCL3
uniprot id: W5PUW9
names: Similarity
messages: Belongs to the phosducin family.

9940:DIS3
gene id: 9940:DIS3
uniprot id: W5Q139
names: Similarity
messages: Belongs to the RNR ribonuclease family.

9940:INTS14
gene id: 9940:INTS14
uniprot id: A0A836A8R2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NETO1
gene id: 9940:NETO1
uniprot id: W5P3Y1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LAMC1
gene id: 9940:LAMC1
uniprot id: A0A6P3EBB2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: basement membrane

9940:PNPLA8
gene id: 9940:PNPLA8
uniprot id: A0A6P3E423
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LEPROT
gene id: 9940:LEPROT
uniprot id: A0A6P3E6F2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LYN
gene id: 9940:LYN
uniprot id: A0A6P3YJC8
uniprot id: A0A6P9FQJ8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDKL1
gene id: 9940:CDKL1
uniprot id: W5QHI5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9940:LOC101115527
gene id: 9940:LOC101115527
uniprot id: A0A6P3E2V5
uniprot id: W5PXS5
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:REEP6
gene id: 9940:REEP6
uniprot id: W5PR68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9940:OSTF1
gene id: 9940:OSTF1
uniprot id: A0A6P3E0U9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PACSIN1
gene id: 9940:PACSIN1
uniprot id: A0A835ZNR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol
messages: ruffle membrane
messages: synaptosome

9940:PLPP1
gene id: 9940:PLPP1
uniprot id: W5PCW9
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

9940:LOXL3
gene id: 9940:LOXL3
uniprot id: W5PTF1
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9940:RPIA
gene id: 9940:RPIA
uniprot id: W5QHY6
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

9940:PPCS
gene id: 9940:PPCS
uniprot id: B2LU23
names: Similarity
messages: Belongs to the PPC synthetase family.

9940:LOC101103376
gene id: 9940:LOC101103376
uniprot id: W5PFU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha/beta interferon family. IFN-alphaII subfamily.
messages: Monomer.
messages: Secreted

9940:CROT
gene id: 9940:CROT
uniprot id: W5PX72
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

9940:AHSG
gene id: 9940:AHSG
uniprot id: P29701
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fetuin family.
messages: Phosphorylated by FAM20C in the extracellular medium.
messages: Secreted

9940:EYA3
gene id: 9940:EYA3
uniprot id: A0A6P3CWU4
uniprot id: C5HK62
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9940:UGT1A4
gene id: 9940:UGT1A4
uniprot id: F1CGV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:KRT222
gene id: 9940:KRT222
uniprot id: W5PZK5
names: Similarity
messages: Belongs to the intermediate filament family.

9940:EML6
gene id: 9940:EML6
uniprot id: W5NYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.
messages: cytoskeleton

9940:S100A14
gene id: 9940:S100A14
uniprot id: A0A6P3ENL8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC9A3R1
gene id: 9940:SLC9A3R1
uniprot id: A0A836A4A2
uniprot id: W5PRP1
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: filopodium
messages: microvillus
messages: ruffle

9940:PCGF5
gene id: 9940:PCGF5
uniprot id: A0A6P3TFE4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:APOOL
gene id: 9940:APOOL
uniprot id: A0A6P3EF61
uniprot id: W5NVI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS29
gene id: 9940:VPS29
uniprot id: A0A6P3EHV4
uniprot id: W5Q644
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGMAT
gene id: 9940:AGMAT
uniprot id: W5PHZ9
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

9940:LOC101122504
gene id: 9940:LOC101122504
uniprot id: W5NVP1
names: Similarity
messages: Belongs to the TCP11 family.

9940:LOC101107442
gene id: 9940:LOC101107442
uniprot id: A0A6P3TNE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:FCF1
gene id: 9940:FCF1
uniprot id: A0A6P3EBE2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:KIAA1143
gene id: 9940:KIAA1143
uniprot id: A0A6P3EEF8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TSN
gene id: 9940:TSN
uniprot id: A0A6P3E6G0
uniprot id: W5PV21
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POSTN
gene id: 9940:POSTN
uniprot id: W5PK02
uniprot id: W5PK03
names: Subcellular Location Annotation
messages: extracellular matrix

9940:LOC101117235
gene id: 9940:LOC101117235
uniprot id: A0A6P3E3D8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120495
gene id: 9940:LOC101120495
uniprot id: W5NY83
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

9940:GPR141
gene id: 9940:GPR141
uniprot id: A0A6P3E4S8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HABP4
gene id: 9940:HABP4
uniprot id: A0A6P3EAH8
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPD52L2
gene id: 9940:TPD52L2
uniprot id: A0A6P3YKV8
names: Caution
names: Similarity
messages: Belongs to the TPD52 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP1R21
gene id: 9940:PPP1R21
uniprot id: W5P3K4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9940:LHB
gene id: 9940:LHB
uniprot id: P01231
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. The beta chain can also be formed by LH beta 1, LH beta 2 and LH beta 3.
messages: Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The LH alpha 3/LH beta 3 heterodimer was shown to have potent renotropic and weak gonadotropic activity.
messages: Secreted

9940:MRPL28
gene id: 9940:MRPL28
uniprot id: A0A6P3ERD3
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOTCH2
gene id: 9940:NOTCH2
uniprot id: W5QGV9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9940:RBBP6
gene id: 9940:RBBP6
uniprot id: A0A6P3EQT2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KPNA5
gene id: 9940:KPNA5
uniprot id: W5PGW2
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9940:GCG
gene id: 9940:GCG
uniprot id: A0A6P3TML5
uniprot id: W5P8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

9940:CORO2B
gene id: 9940:CORO2B
uniprot id: W5QAZ1
names: Similarity
messages: Belongs to the WD repeat coronin family.

9940:TBC1D22B
gene id: 9940:TBC1D22B
uniprot id: A0A6P3ECH8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:REN
gene id: 9940:REN
uniprot id: P52115
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the peptidase A1 family.
messages: Interaction with ATP6AP2 results in a 5-fold increased efficiency in angiotensinogen processing.
messages: Interacts with ATP6AP2.
messages: Kidney.
messages: Membrane
messages: Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
messages: Secreted

9940:PHF1
gene id: 9940:PHF1
uniprot id: A0A6P3YNA0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDIP1
gene id: 9940:CDIP1
uniprot id: A0A6P3EE31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

9940:SERPINH1
gene id: 9940:SERPINH1
uniprot id: A0A6P9FR52
names: Function
names: Similarity
messages: Belongs to the serpin family.
messages: Binds specifically to collagen. Could be involved as a chaperone in the biosynthetic pathway of collagen.

9940:FOXJ3
gene id: 9940:FOXJ3
uniprot id: W5QGR2
names: Subcellular Location Annotation
messages: Nucleus

9940:TFCP2L1
gene id: 9940:TFCP2L1
uniprot id: A0A6P3E1I1
uniprot id: W5PUC9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HINT2
gene id: 9940:HINT2
uniprot id: W5PQ45
names: Similarity
messages: Belongs to the HINT family.

9940:LSM10
gene id: 9940:LSM10
uniprot id: A0A6P3E4T9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PGK1
gene id: 9940:PGK1
uniprot id: A0A6P9FRD7
uniprot id: B7TJ13
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TM2D2
gene id: 9940:TM2D2
uniprot id: A0A6P3EML1
uniprot id: W5NUN2
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120929
gene id: 9940:LOC101120929
uniprot id: W5P273
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:AIF1
gene id: 9940:AIF1
uniprot id: W5PDK4
names: Subcellular Location Annotation
messages: ruffle membrane

9940:TSNAX
gene id: 9940:TSNAX
uniprot id: A0A6P3EED9
uniprot id: W5NZ92
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TFE3
gene id: 9940:TFE3
uniprot id: A0A6P3EH84
uniprot id: W5PND3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRPV2
gene id: 9940:TRPV2
uniprot id: W5Q612
names: Subcellular Location Annotation
messages: Membrane

9940:MAN2A1
gene id: 9940:MAN2A1
uniprot id: W5QC34
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9940:NR5A2
gene id: 9940:NR5A2
uniprot id: G1FEX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9940:TP63
gene id: 9940:TP63
uniprot id: W5QGZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Endoplasmic reticulum
messages: Mitochondrion matrix
messages: PML body
messages: centrosome

9940:IL17B
gene id: 9940:IL17B
uniprot id: W5P5J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9940:LOC101102969
gene id: 9940:LOC101102969
uniprot id: W5QGS8
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9940:HOXA10
gene id: 9940:HOXA10
uniprot id: W5PIV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9940:LOC101122737
gene id: 9940:LOC101122737
uniprot id: A0A6P3DY62
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL10A
gene id: 9940:RPL10A
uniprot id: A0A835ZUS5
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:APOH
gene id: 9940:APOH
uniprot id: W5Q268
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:LOC101104431
gene id: 9940:LOC101104431
uniprot id: W5PWK7
names: Similarity
messages: Belongs to the TAF11 family.

9940:MB
gene id: 9940:MB
uniprot id: A0A6P7DSP6
uniprot id: P02190
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NSUN4
gene id: 9940:NSUN4
uniprot id: W5NWC8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9940:COL4A5
gene id: 9940:COL4A5
uniprot id: A0A6P3ENB1
uniprot id: W5Q9X9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9940:TMEM182
gene id: 9940:TMEM182
uniprot id: W5PU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9940:MRRF
gene id: 9940:MRRF
uniprot id: W5PXI9
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

9940:PRKAA2
gene id: 9940:PRKAA2
uniprot id: A8D245
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm

9940:TMEM14C
gene id: 9940:TMEM14C
uniprot id: W5Q2W7
names: Similarity
messages: Belongs to the TMEM14 family.

9940:GPNMB
gene id: 9940:GPNMB
uniprot id: W5PT76
names: Similarity
messages: Belongs to the PMEL/NMB family.

9940:FMR1
gene id: 9940:FMR1
uniprot id: W5PIV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cell membrane
messages: Cytoplasmic ribonucleoprotein granule
messages: Membrane
messages: Perikaryon
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: centromere
messages: dendrite
messages: dendritic spine
messages: filopodium tip
messages: growth cone
messages: neuron projection
messages: nucleolus
messages: perinuclear region
messages: synaptosome

9940:LYZL4
gene id: 9940:LYZL4
uniprot id: F2X045
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9940:TCP11L1
gene id: 9940:TCP11L1
uniprot id: A0A6P3T5F3
names: Similarity
messages: Belongs to the TCP11 family.

9940:DNAAF8
gene id: 9940:DNAAF8
uniprot id: A0A6P7DF52
names: Function
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

9940:PDZK1IP1
gene id: 9940:PDZK1IP1
uniprot id: W5NZR4
names: Subcellular Location Annotation
messages: Membrane

9940:PLD3
gene id: 9940:PLD3
uniprot id: A0A836A161
uniprot id: W5P9G8
names: Caution
names: Similarity
messages: Belongs to the phospholipase D family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LRRC42
gene id: 9940:LRRC42
uniprot id: W5P9W3
names: Similarity
messages: Belongs to the LRRC42 family.

9940:A2ML1
gene id: 9940:A2ML1
uniprot id: W5NUD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9940:ERCC6L
gene id: 9940:ERCC6L
uniprot id: A0A835ZFW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRYAA
gene id: 9940:CRYAA
uniprot id: A0A836AQL0
uniprot id: Q5ENZ0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation at Lys-70 may increase chaperone activity.
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. Acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
messages: Cytoplasm
messages: Heteromer composed of three CRYAA and one CRYAB subunits. Inter-subunit bridging via zinc ions enhances stability, which is crucial as there is no protein turn over in the lens. Can also form homodimers and homotetramers (dimers of dimers) which serve as the building blocks of homooligomers (By similarity). Within homooligomers, the zinc-binding motif is created from residues of 3 different molecules. His-100 and Glu-102 from one molecule are ligands of the zinc ion, and His-107 and His-154 residues from additional molecules complete the site with tetrahedral coordination geometry (By similarity). Part of a complex required for lens intermediate filament formation composed of BFSP1, BFSP2 and CRYAA (By similarity).
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Undergoes age-dependent proteolytical cleavage at the C-terminus.

9940:TXLNA
gene id: 9940:TXLNA
uniprot id: W5NQQ4
names: Similarity
messages: Belongs to the taxilin family.

9940:HSPA9
gene id: 9940:HSPA9
uniprot id: A0A6P3E4S6
uniprot id: W5Q4W8
names: Caution
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105014
gene id: 9940:LOC101105014
uniprot id: A0A6P3YNF4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BTF3L4
gene id: 9940:BTF3L4
uniprot id: A0A6P3E3Z1
names: Similarity
messages: Belongs to the NAC-beta family.

9940:IRAK4
gene id: 9940:IRAK4
uniprot id: B7U176
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with MYD88 and IRAK2 to form a ternary complex called the Myddosome.
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. Pelle subfamily.
messages: Cytoplasm
messages: Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens.

9940:LOC101104225
gene id: 9940:LOC101104225
uniprot id: A0A6P3YIT3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CTNNB1
gene id: 9940:CTNNB1
uniprot id: M4WGF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: adherens junction

9940:SNRPE
gene id: 9940:SNRPE
uniprot id: A0A6P3EAV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:MIEF2
gene id: 9940:MIEF2
uniprot id: W5NQ74
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9940:RND1
gene id: 9940:RND1
uniprot id: A0A6P3TEL2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL44
gene id: 9940:MRPL44
uniprot id: A0A836D7B1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ribonuclease III family. Mitochondrion-specific ribosomal protein mL44 subfamily.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101105540
gene id: 9940:LOC101105540
uniprot id: W5PFK2
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:LOC101114212
gene id: 9940:LOC101114212
uniprot id: W5P863
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SNAPC5
gene id: 9940:SNAPC5
uniprot id: A0A6P3TNP2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123349
gene id: 9940:LOC101123349
uniprot id: A0A6P3E105
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm
messages: podosome

9940:PDHA1
gene id: 9940:PDHA1
uniprot id: A0A6P3EEU7
uniprot id: W5PYS5
names: Caution
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLN3
gene id: 9940:CLN3
uniprot id: A0A6P3T5T4
uniprot id: A0A6P7DGL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MC2R
gene id: 9940:MC2R
uniprot id: Q9TU77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH) (By similarity).
messages: Receptor for corticotropin (ACTH). This receptor is mediated by G proteins which activate adenylate cyclase (cAMP).

9940:C1QA
gene id: 9940:C1QA
uniprot id: A0A6P3TNH6
uniprot id: W5PDS4
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

9940:HACD3
gene id: 9940:HACD3
uniprot id: A0A6P3TF92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTM1
gene id: 9940:MTM1
uniprot id: W5PGL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

9940:MYC
gene id: 9940:MYC
uniprot id: A0A836AC69
uniprot id: Q28566
names: Caution
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as a heterodimer with MAX (By similarity). Interacts with TAF1C and SPAG9. Interacts with PARP10. Interacts with KDM5A and KDM5B. Interacts (when phosphorylated at Thr-58 and Ser-62) with FBXW7. Interacts with PIM2. Interacts with RIOX1. The heterodimer MYC:MAX interacts with ABI1; the interaction may enhance MYC:MAX transcriptional activity. Interacts with TRIM6 (By similarity). Interacts with NPM1; the binary complex is recruited to the promoter of MYC target genes and enhances their transcription (By similarity). Interacts with CIP2A; leading to the stabilization of MYC (By similarity).
messages: Phosphorylated by PRKDC (By similarity). Phosphorylation at Ser-329 by PIM2 leads to the stabilization of MYC (By similarity). Phosphorylation at Ser-62 by CDK2 prevents Ras-induced senescence. Phosphorylated at Ser-62 by DYRK2; this primes the protein for subsequent phosphorylation by GSK3B at Thr-58. Phosphorylation at Thr-58 and Ser-62 by GSK3 is required for ubiquitination and degradation by the proteasome. Dephosphorylation at Ser-62 by protein phosphatase 2A (PPP2CA) promotes its degradation; interaction with PPP2CA is enhanced by AMBRA1 (By similarity).
messages: The 9aaTAD motif is a transactivation domain present in a large number of yeast and animal transcription factors.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform (By similarity).
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release (By similarity). Positively regulates transcription of HNRNPA1, HNRNPA2 and PTBP1 which in turn regulate splicing of pyruvate kinase PKM by binding repressively to sequences flanking PKM exon 9, inhibiting exon 9 inclusion and resulting in exon 10 inclusion and production of the PKM M2 isoform.
messages: Ubiquitinated by the SCF(FBXW7) complex when phosphorylated at Thr-58 and Ser-62, leading to its degradation by the proteasome. Ubiquitination is counteracted by USP28 in the nucleoplasm and USP36 in the nucleolus, both interacting with of FBXW7, leading to its deubiquitination and preventing degradation. Also polyubiquitinated by the DCX(TRPC4AP) complex. Ubiquitinated by TRIM6 in a phosphorylation-independent manner.
messages: nucleolus
messages: nucleoplasm

9940:DPP4
gene id: 9940:DPP4
uniprot id: A0A6P3E8N0
uniprot id: W5P906
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: invadopodium membrane
messages: lamellipodium membrane

9940:NT5C1A
gene id: 9940:NT5C1A
uniprot id: A0A6P3DY36
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123031
gene id: 9940:LOC101123031
uniprot id: W5NTD4
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9940:DAZAP2
gene id: 9940:DAZAP2
uniprot id: A0A6P3TEI1
uniprot id: W5Q7F0
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus speckle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nuclear body

9940:SCFD2
gene id: 9940:SCFD2
uniprot id: W5QBH7
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9940:DRG1
gene id: 9940:DRG1
uniprot id: A0A6P3EBM6
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KHK
gene id: 9940:KHK
uniprot id: A0A6P3E9S5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLK4
gene id: 9940:PLK4
uniprot id: W5Q2A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Cleavage furrow
messages: centriole

9940:HELLS
gene id: 9940:HELLS
uniprot id: A0A6P3EKP1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPM1
gene id: 9940:TPM1
uniprot id: A0A6P3TI22
uniprot id: A0A6P9FRC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:SLC25A53
gene id: 9940:SLC25A53
uniprot id: W5NR05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:SLC17A3
gene id: 9940:SLC17A3
uniprot id: W5NV35
names: Subcellular Location Annotation
messages: Membrane

9940:NFATC3
gene id: 9940:NFATC3
uniprot id: A0A836A1M7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPLP1
gene id: 9940:RPLP1
uniprot id: A0A6P3EFI8
uniprot id: W5QBE7
names: Caution
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.
messages: Plays an important role in the elongation step of protein synthesis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117112
gene id: 9940:LOC101117112
uniprot id: A0A6P3EEC7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PKIA
gene id: 9940:PKIA
uniprot id: W5PCA8
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9940:HEATR3
gene id: 9940:HEATR3
uniprot id: A0A6P3EKZ4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GLT8D2
gene id: 9940:GLT8D2
uniprot id: A0A6P3EC14
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VPS16
gene id: 9940:VPS16
uniprot id: W5P5A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

9940:TIMP3
gene id: 9940:TIMP3
uniprot id: A0A6P3CXN5
uniprot id: C8BKC2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts with EFEMP1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:TFAP2D
gene id: 9940:TFAP2D
uniprot id: W5PT23
names: Similarity
messages: Belongs to the AP-2 family.

9940:CHST4
gene id: 9940:CHST4
uniprot id: W5PNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9940:ATP6V1G3
gene id: 9940:ATP6V1G3
uniprot id: A0A836A030
uniprot id: W5Q1X7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:PDS5B
gene id: 9940:PDS5B
uniprot id: W5PMP0
names: Similarity
messages: Belongs to the PDS5 family.

9940:PAG9
gene id: 9940:PAG9
uniprot id: O02729
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:RAB6B
gene id: 9940:RAB6B
uniprot id: A0A6P3E0I9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR3A
gene id: 9940:POLR3A
uniprot id: A0A835ZM08
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC6A13
gene id: 9940:SLC6A13
uniprot id: W5PQF4
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A13 subfamily.
messages: Cell membrane
messages: Membrane

9940:SLC17A8
gene id: 9940:SLC17A8
uniprot id: W5PWE1
names: Subcellular Location Annotation
messages: Membrane

9940:SLC30A5
gene id: 9940:SLC30A5
uniprot id: W5P725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Membrane
messages: trans-Golgi network membrane

9940:DDX47
gene id: 9940:DDX47
uniprot id: A0A6P3ECB4
names: Caution
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADGRF2
gene id: 9940:ADGRF2
uniprot id: W5PQ63
names: Subcellular Location Annotation
messages: Membrane

9940:SMAD6
gene id: 9940:SMAD6
uniprot id: W5QA49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9940:ESCO1
gene id: 9940:ESCO1
uniprot id: W5PF58
names: Subcellular Location Annotation
messages: Nucleus

9940:BMS1
gene id: 9940:BMS1
uniprot id: A0A6P3TA50
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:PAG5
gene id: 9940:PAG5
uniprot id: O02725
names: Similarity
messages: Belongs to the peptidase A1 family.

9940:KEF53 p05
gene id: 9940:KEF53_p05
uniprot id: O78754
uniprot id: Q5MA69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

9940:LOC101106380
gene id: 9940:LOC101106380
uniprot id: A0A6P3EDH9
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIPG
gene id: 9940:LIPG
uniprot id: A0A6P3T9I6
uniprot id: W5P1I2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:DNMT1
gene id: 9940:DNMT1
uniprot id: Q865V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

9940:RNASE2
gene id: 9940:RNASE2
uniprot id: W5QEN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9940:LOC101116323
gene id: 9940:LOC101116323
uniprot id: A0A6P3E763
uniprot id: W5Q0T4
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RMND1
gene id: 9940:RMND1
uniprot id: A0A6P3TRQ1
names: Similarity
messages: Belongs to the RMD1/sif2 family.

9940:GSTK1
gene id: 9940:GSTK1
uniprot id: W5Q894
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

9940:PSMA5
gene id: 9940:PSMA5
uniprot id: A0A6P3E480
uniprot id: W5QD30
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRB14
gene id: 9940:GRB14
uniprot id: W5P757
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9940:LOC100526782
gene id: 9940:LOC100526782
uniprot id: E3VW78
names: Similarity
messages: Belongs to the intermediate filament family.

9940:LOC101105081
gene id: 9940:LOC101105081
uniprot id: W5PXX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:BCKDK
gene id: 9940:BCKDK
uniprot id: A0A6P3ERN3
uniprot id: A0A6P3TJS6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GOLT1B
gene id: 9940:GOLT1B
uniprot id: A0A6P3EB59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATG9A
gene id: 9940:ATG9A
uniprot id: A0A6P3TI19
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

9940:BDH1
gene id: 9940:BDH1
uniprot id: A0A6P3DZQ0
uniprot id: A0A836AEX2
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CENPN
gene id: 9940:CENPN
uniprot id: W5PED9
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

9940:FGF13
gene id: 9940:FGF13
uniprot id: A0A6P3EF81
uniprot id: W5PLX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

9940:MTNR1B
gene id: 9940:MTNR1B
uniprot id: A0A6P3CX01
uniprot id: B4YTT7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABRA4
gene id: 9940:GABRA4
uniprot id: W5Q1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:INO80E
gene id: 9940:INO80E
uniprot id: A0A6P3EQU8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMCO6
gene id: 9940:TMCO6
uniprot id: A0A6P3ECZ1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CXCL10
gene id: 9940:CXCL10
uniprot id: A0A6P3CWG0
uniprot id: Q95MZ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:VDAC2
gene id: 9940:VDAC2
uniprot id: W5PG36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

9940:GOSR1
gene id: 9940:GOSR1
uniprot id: A0A6P3EIA5
uniprot id: W5PMP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110185
gene id: 9940:LOC101110185
uniprot id: A0A6P3EJI1
uniprot id: A0A836CTR2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GSC
gene id: 9940:GSC
uniprot id: W5Q1C1
names: Subcellular Location Annotation
messages: Nucleus

9940:GOT2
gene id: 9940:GOT2
uniprot id: A0A6P3EFE9
uniprot id: W5NUG0
names: Caution
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD1D
gene id: 9940:CD1D
uniprot id: O62848
names: Function
names: Miscellaneous
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
messages: Basolateral cell membrane
messages: Cell membrane
messages: During protein synthesis and maturation, CD1 family members bind endogenous lipids that are replaced by lipid or glycolipid antigens when the proteins are internalized and pass through endosomes, before trafficking back to the cell surface.
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
messages: Heterodimer with B2M (beta-2-microglobulin). Interacts with MHC II and CD74 (By similarity).
messages: Lysosome membrane

9940:RIMS3
gene id: 9940:RIMS3
uniprot id: A0A6P3TL03
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1R
gene id: 9940:C1R
uniprot id: A0A836AKC1
names: Caution
names: Function
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SELP
gene id: 9940:SELP
uniprot id: A0A835ZZD9
uniprot id: P98109
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selectin/LECAM family.
messages: Ca(2+)-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. Mediates the interaction of activated endothelial cells or platelets with leukocytes. The ligand recognized is sialyl-Lewis X. Mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with SELPLG.
messages: Cell membrane
messages: Interacts with SNX17. Interacts with SELPLG/PSGL1 and PODXL2 and mediates neutrophil adhesion and leukocyte rolling. This interaction requires the sialyl-Lewis X epitope of SELPLG and PODXL2, and specific tyrosine sulfation on SELPLG.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPY1R
gene id: 9940:NPY1R
uniprot id: A0A6P3TSX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:PNMA2
gene id: 9940:PNMA2
uniprot id: W5PE65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNMA family.
messages: nucleolus

9940:KIAA0513
gene id: 9940:KIAA0513
uniprot id: A0A6P3TK17
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAF3IP2
gene id: 9940:TRAF3IP2
uniprot id: A0A6P3EBP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMC5
gene id: 9940:SMC5
uniprot id: A0A6P3E198
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLDN3
gene id: 9940:CLDN3
uniprot id: A0A6P3EGH8
uniprot id: W5PMF3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:LOC101106554
gene id: 9940:LOC101106554
uniprot id: W5Q443
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9940:GZMA
gene id: 9940:GZMA
uniprot id: A0A835ZYS4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAX1BP3
gene id: 9940:TAX1BP3
uniprot id: W5Q7I8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites.
messages: Nucleus

9940:LIN7C
gene id: 9940:LIN7C
uniprot id: A0A6P3EKU5
uniprot id: W5Q0E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: tight junction

9940:RUNX1T1
gene id: 9940:RUNX1T1
uniprot id: A0A3S5HL72
names: Similarity
messages: Belongs to the CBFA2T family.

9940:CCND2
gene id: 9940:CCND2
uniprot id: A0A6P3CX20
uniprot id: B2MVY2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YPEL2
gene id: 9940:YPEL2
uniprot id: A0A6P3YNP6
names: Similarity
messages: Belongs to the yippee family.

9940:ALKBH2
gene id: 9940:ALKBH2
uniprot id: A0A835ZRS5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GATA1
gene id: 9940:GATA1
uniprot id: F8WQV2
names: Subcellular Location Annotation
messages: Nucleus

9940:LOC101102078
gene id: 9940:LOC101102078
uniprot id: W5QAX9
names: Similarity
messages: Belongs to the MHC class I family.

9940:RBM7
gene id: 9940:RBM7
uniprot id: A0A6P3TF62
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALDH8A1
gene id: 9940:ALDH8A1
uniprot id: A0A6P3E8Q3
uniprot id: W5PZD2
names: Caution
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ETNPPL
gene id: 9940:ETNPPL
uniprot id: A0A836D222
uniprot id: W5PCA1
names: Caution
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OCA2
gene id: 9940:OCA2
uniprot id: W5Q262
names: Subcellular Location Annotation
messages: Membrane

9940:AGTR1
gene id: 9940:AGTR1
uniprot id: A0A6P3CWL5
uniprot id: Q9N0U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122747
gene id: 9940:LOC101122747
uniprot id: W5QHG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:LPO
gene id: 9940:LPO
uniprot id: A0A8N7XJI5
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110447
gene id: 9940:LOC101110447
uniprot id: W5PQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:FERD3L
gene id: 9940:FERD3L
uniprot id: A0A6P3TR49
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNX7
gene id: 9940:SNX7
uniprot id: W5Q820
names: Similarity
messages: Belongs to the sorting nexin family.

9940:LOC101113096
gene id: 9940:LOC101113096
uniprot id: W5P9A9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:IL2
gene id: 9940:IL2
uniprot id: P19114
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-2 family.
messages: Cytokine produced by activated CD4-positive helper T-cells and to a lesser extend activated CD8-positive T-cells and natural killer (NK) cells that plays pivotal roles in the immune response and tolerance. Binds to a receptor complex composed of either the high-affinity trimeric IL-2R (IL2RA/CD25, IL2RB/CD122 and IL2RG/CD132) or the low-affinity dimeric IL-2R (IL2RB and IL2RG). Interaction with the receptor leads to oligomerization and conformation changes in the IL-2R subunits resulting in downstream signaling starting with phosphorylation of JAK1 and JAK3. In turn, JAK1 and JAK3 phosphorylate the receptor to form a docking site leading to the phosphorylation of several substrates including STAT5. This process leads to activation of several pathways including STAT, phosphoinositide-3-kinase/PI3K and mitogen-activated protein kinase/MAPK pathways. Functions as a T-cell growth factor and can increase NK-cell cytolytic activity as well. Promotes strong proliferation of activated B-cells and subsequently immunoglobulin production. Plays a pivotal role in regulating the adaptive immune system by controlling the survival and proliferation of regulatory T-cells, which are required for the maintenance of immune tolerance. Moreover, participates in the differentiation and homeostasis of effector T-cell subsets, including Th1, Th2, Th17 as well as memory CD8-positive T-cells.
messages: Secreted

9940:TRIQK
gene id: 9940:TRIQK
uniprot id: A0A6P3TVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:THAP3
gene id: 9940:THAP3
uniprot id: A0A6P3EB67
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDR3
gene id: 9940:WDR3
uniprot id: A0A6P3E6Y6
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:CSPP1
gene id: 9940:CSPP1
uniprot id: A0A836A185
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRS2
gene id: 9940:MRS2
uniprot id: A0A6P3EJN4
uniprot id: W5PBP8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DLAT
gene id: 9940:DLAT
uniprot id: W5Q2C5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

9940:ARAP2
gene id: 9940:ARAP2
uniprot id: W5PHT4
names: Subcellular Location Annotation
messages: Cytoplasm

9940:TMEM67
gene id: 9940:TMEM67
uniprot id: A0A836ABU9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLAIN2
gene id: 9940:SLAIN2
uniprot id: A0A6P3YIE1
uniprot id: W5Q6T7
names: Caution
names: Similarity
messages: Belongs to the SLAIN motif-containing family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114432
gene id: 9940:LOC101114432
uniprot id: A0A6P3TEW9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RXRG
gene id: 9940:RXRG
uniprot id: A0A6P3TSV9
uniprot id: W5PP44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9940:SCNM1
gene id: 9940:SCNM1
uniprot id: A0A6P3DYZ6
uniprot id: W5QIF0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleoplasm

9940:CTPS2
gene id: 9940:CTPS2
uniprot id: A0A6P3YPN8
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

9940:ERGIC1
gene id: 9940:ERGIC1
uniprot id: A0A6P3YN45
uniprot id: W5P1G5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101111629
gene id: 9940:LOC101111629
uniprot id: W5PT32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SOD2
gene id: 9940:SOD2
uniprot id: A0A6P9FRH0
uniprot id: C8BKD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPHP1
gene id: 9940:NPHP1
uniprot id: A0A6P3E2M3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IFIH1
gene id: 9940:IFIH1
uniprot id: W5P823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

9940:PIK3R1
gene id: 9940:PIK3R1
uniprot id: A0A835ZYC1
names: Caution
names: Similarity
messages: Belongs to the PI3K p85 subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106323
gene id: 9940:LOC101106323
uniprot id: A0A6P3E5M7
uniprot id: W5P8B9
names: Caution
names: Similarity
messages: Belongs to the peptidase S14 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101118849
gene id: 9940:LOC101118849
uniprot id: W5NWG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9940:PVALB
gene id: 9940:PVALB
uniprot id: A0A6P3E3J6
names: Caution
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TWIST2
gene id: 9940:TWIST2
uniprot id: A0A6P3DYJ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTO1
gene id: 9940:MTO1
uniprot id: W5P818
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

9940:DLG1
gene id: 9940:DLG1
uniprot id: A0A6P7D2W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane

9940:MRPL34
gene id: 9940:MRPL34
uniprot id: W5Q709
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

9940:RBP5
gene id: 9940:RBP5
uniprot id: A0A6P7DZS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9940:PARP8
gene id: 9940:PARP8
uniprot id: W5PF05
names: Similarity
messages: Belongs to the ARTD/PARP family.

9940:FANCC
gene id: 9940:FANCC
uniprot id: W5PFM1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

9940:DCTN6
gene id: 9940:DCTN6
uniprot id: A0A6P3EGY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:INPP1
gene id: 9940:INPP1
uniprot id: A0A6P7DPC6
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9940:TM4SF20
gene id: 9940:TM4SF20
uniprot id: A0A6P3E228
uniprot id: W5QH90
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ANXA11
gene id: 9940:ANXA11
uniprot id: W5PJM4
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9940:GINS3
gene id: 9940:GINS3
uniprot id: A0A6P3E9L7
uniprot id: W5NTH9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106894
gene id: 9940:LOC101106894
uniprot id: A0A835ZX15
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPATA7
gene id: 9940:SPATA7
uniprot id: A0A836D1Y3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EFNA3
gene id: 9940:EFNA3
uniprot id: A0A6P3E622
uniprot id: W5P072
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RNF145
gene id: 9940:RNF145
uniprot id: A0A6P3TMH9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YARS1
gene id: 9940:YARS1
uniprot id: A0A836AGY1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DMAP1
gene id: 9940:DMAP1
uniprot id: W5NRN7
names: Subcellular Location Annotation
messages: Nucleus

9940:SAV1
gene id: 9940:SAV1
uniprot id: A0A6P3EG01
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM231
gene id: 9940:TMEM231
uniprot id: W5PA73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM231 family.
messages: Membrane
messages: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling.
messages: cilium membrane

9940:NMNAT1
gene id: 9940:NMNAT1
uniprot id: A0A6P3EE65
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

9940:GDAP2
gene id: 9940:GDAP2
uniprot id: A0A6P3E4B2
uniprot id: W5QGH2
names: Caution
names: Similarity
messages: Belongs to the GDAP2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GID8
gene id: 9940:GID8
uniprot id: A0A6P3EKJ2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V1F
gene id: 9940:ATP6V1F
uniprot id: A0A6P3EC42
uniprot id: W5NZZ3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:CCT2
gene id: 9940:CCT2
uniprot id: W5QGG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9940:P2RY10
gene id: 9940:P2RY10
uniprot id: A0A836CQF2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNAJC22
gene id: 9940:DNAJC22
uniprot id: A0A6P3E339
uniprot id: W5QBU6
names: Caution
names: Function
names: Subcellular Location Annotation
messages: May function as a co-chaperone.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AHR
gene id: 9940:AHR
uniprot id: W5PHJ3
names: Subcellular Location Annotation
messages: Cytoplasm

9940:SGTA
gene id: 9940:SGTA
uniprot id: A0A6P3TGT9
uniprot id: A0A6P3TS61
names: Caution
names: Similarity
messages: Belongs to the SGT family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLK1
gene id: 9940:PLK1
uniprot id: A0A6P3ERK0
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114017
gene id: 9940:LOC101114017
uniprot id: W5Q5P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101117724
gene id: 9940:LOC101117724
uniprot id: W5PAU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101119515
gene id: 9940:LOC101119515
uniprot id: W5PGS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ATP6V0A1
gene id: 9940:ATP6V0A1
uniprot id: A0A6P3TL70
uniprot id: W5NV03
uniprot id: W5NV06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SERTAD1
gene id: 9940:SERTAD1
uniprot id: A0A836A3V8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADRA1D
gene id: 9940:ADRA1D
uniprot id: W5NPZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

9940:LOC101121762
gene id: 9940:LOC101121762
uniprot id: A0A6P3E3V5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTPN6
gene id: 9940:PTPN6
uniprot id: A0A6P3TC87
uniprot id: W5P4P3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110938
gene id: 9940:LOC101110938
uniprot id: A0A836D1P3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LMLN
gene id: 9940:LMLN
uniprot id: W5QGA1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M8 family.
messages: Binds 1 zinc ion per subunit.

9940:ANAPC7
gene id: 9940:ANAPC7
uniprot id: A0A6P3EM85
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLIP1
gene id: 9940:CLIP1
uniprot id: A0A6P3YMB9
uniprot id: W5PNE4
names: Subcellular Location Annotation
messages: cytoskeleton

9940:FAM151B
gene id: 9940:FAM151B
uniprot id: W5PZI2
names: Similarity
messages: Belongs to the FAM151 family.

9940:UBE2D4
gene id: 9940:UBE2D4
uniprot id: A0A6P3TDP8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:RPS19BP1
gene id: 9940:RPS19BP1
uniprot id: A0A6P3E3L2
uniprot id: W5Q5N4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:USP4
gene id: 9940:USP4
uniprot id: A0A836CSV2
uniprot id: W5PX00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Cytoplasm
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GSTA1
gene id: 9940:GSTA1
uniprot id: B0LXN9
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9940:LRG1
gene id: 9940:LRG1
uniprot id: A0A836A8G3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF3E
gene id: 9940:EIF3E
uniprot id: W5PZH7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

9940:LOC101115856
gene id: 9940:LOC101115856
uniprot id: W5PSY6
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.

9940:LOC101110177
gene id: 9940:LOC101110177
uniprot id: W5PN49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9940:LOC101103491
gene id: 9940:LOC101103491
uniprot id: W5NWH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

9940:AIPL1
gene id: 9940:AIPL1
uniprot id: W5NVZ7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be important in protein trafficking and/or protein folding and stabilization.
messages: Nucleus

9940:LOC101112585
gene id: 9940:LOC101112585
uniprot id: A0A6P3E8P3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CAV1
gene id: 9940:CAV1
uniprot id: Q6B3Y2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Homooligomer. Interacts (via the N-terminus) with DPP4; the interaction is direct. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Interacts with PACSIN2; this interaction induces membrane tubulation (By similarity). Interacts with BMX, BTK, CTNNB1, CDH1, GLIPR2, JUP, NOSTRIN, SNAP25 and STX1A. Interacts with SLC7A9. Interacts with TGFBR1. Interacts with CAVIN3 (via leucine-zipper domain) in a cholesterol-sensitive manner. Interacts with CAVIN1. Interacts with EHD2 in a cholesterol-dependent manner. Forms a ternary complex with UBXN6 and VCP; mediates CAV1 targeting to lysosomes for degradation. Interacts with ABCG1; this interaction regulates ABCG1-mediated cholesterol efflux (By similarity). Interacts with NEU3; this interaction enhances NEU3 sialidase activity within caveola. Interacts (via C-terminus) with SPRY1, SPRY2 (via C-terminus), SPRY3, and SPRY4 (By similarity).
messages: May act as a scaffolding protein within caveolar membranes. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1/2/3/4) to the caveolae (By similarity). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner (By similarity). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). Negatively regulates TGFB1-mediated activation of SMAD2/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (By similarity).
messages: Membrane raft
messages: Phosphorylated at Tyr-14 by ABL1 in response to oxidative stress.
messages: Ubiquitinated. Undergo monoubiquitination and multi- and/or polyubiquitination. Monoubiquitination of N-terminal lysines promotes integration in a ternary complex with UBXN6 and VCP which promotes oligomeric CAV1 targeting to lysosomes for degradation.
messages: caveola

9940:CYLD
gene id: 9940:CYLD
uniprot id: A0A6P3YQD0
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

9940:BMPR1A
gene id: 9940:BMPR1A
uniprot id: A0A6P3TJY5
uniprot id: A0A6P9FQW2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:POLR2F
gene id: 9940:POLR2F
uniprot id: A0A6P3ECI5
uniprot id: W5PZ74
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I), RNA polymerase II (Pol II) and RNA polymerase III (Pol III) complexes consisting of at least 13, 12 and 17 subunits, respectively.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ST8SIA1
gene id: 9940:ST8SIA1
uniprot id: W5QG20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9940:NCALD
gene id: 9940:NCALD
uniprot id: A0A6P3E970
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MTFP1
gene id: 9940:MTFP1
uniprot id: A0A835ZQ77
uniprot id: W5PC75
names: Caution
names: Similarity
messages: Belongs to the MTFP1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPIL4
gene id: 9940:PPIL4
uniprot id: A0A836A8A9
uniprot id: W5NXE7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123244
gene id: 9940:LOC101123244
uniprot id: W5NVY5
names: Similarity
messages: Belongs to the serpin family.

9940:GPBP1
gene id: 9940:GPBP1
uniprot id: A0A6P3EHC2
uniprot id: A0A835ZQL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YAE1
gene id: 9940:YAE1
uniprot id: W5Q8D5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9940:FAM180A
gene id: 9940:FAM180A
uniprot id: A0A6P3TN27
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STX16
gene id: 9940:STX16
uniprot id: A0A6P3E987
uniprot id: A0A6P3TTF7
names: Caution
names: Similarity
messages: Belongs to the syntaxin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARG2
gene id: 9940:ARG2
uniprot id: A0A6P3E6D5
uniprot id: W5QJ54
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNCA
gene id: 9940:SNCA
uniprot id: A0A6P3TPE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

9940:C15H11orf1
gene id: 9940:C15H11orf1
uniprot id: A0A6P3ELY4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LYRM4
gene id: 9940:LYRM4
uniprot id: A0A6P3EP55
names: Caution
names: Similarity
messages: Belongs to the complex I LYR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DCN
gene id: 9940:DCN
uniprot id: A0A6P3TDF7
uniprot id: Q9TTE2
uniprot id: W5Q2F5
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT (By similarity).
messages: Binds to type I and type II collagen, fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN. Interacts with DPT.
messages: May affect the rate of fibrils formation.
messages: The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:EBF2
gene id: 9940:EBF2
uniprot id: W5PJB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9940:CDH10
gene id: 9940:CDH10
uniprot id: W5PT86
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9940:SUPT5H
gene id: 9940:SUPT5H
uniprot id: W5P866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus

9940:OPTN
gene id: 9940:OPTN
uniprot id: A0A6P3TJ90
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

9940:LOC101112671
gene id: 9940:LOC101112671
uniprot id: A0A6P3EME1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:BMP5
gene id: 9940:BMP5
uniprot id: A0A6P3ECG4
uniprot id: W5P8S3
names: Caution
names: Similarity
messages: Belongs to the TGF-beta family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CRYGN
gene id: 9940:CRYGN
uniprot id: A0A6P3YL84
names: Caution
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPN1
gene id: 9940:CPN1
uniprot id: W5PV54
names: Similarity
messages: Belongs to the peptidase M14 family.

9940:PRMT5
gene id: 9940:PRMT5
uniprot id: A0A6P3EFL8
uniprot id: W5QDN6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP6V1E1
gene id: 9940:ATP6V1E1
uniprot id: A0A6P3EBD5
uniprot id: W5PVH8
names: Caution
names: Similarity
messages: Belongs to the V-ATPase E subunit family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SHISAL2B
gene id: 9940:SHISAL2B
uniprot id: A0A6P3EHB2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUPT20H
gene id: 9940:SUPT20H
uniprot id: W5PKA8
names: Similarity
messages: Belongs to the SPT20 family.

9940:LOC101112162
gene id: 9940:LOC101112162
uniprot id: W5P3N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9940:ELAVL2
gene id: 9940:ELAVL2
uniprot id: W5PYI5
names: Similarity
messages: Belongs to the RRM elav family.

9940:ADD3
gene id: 9940:ADD3
uniprot id: A0A6P3ER13
names: Caution
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101110974
gene id: 9940:LOC101110974
uniprot id: A0A6P3ECW6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HYAL1
gene id: 9940:HYAL1
uniprot id: W5PIU5
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9940:GPR50
gene id: 9940:GPR50
uniprot id: Q28558
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Does not bind melatonin.
messages: Homodimer, and heterodimer with MTNR1A and MTNR1B.

9940:CA5B
gene id: 9940:CA5B
uniprot id: W5PT28
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9940:CNTNAP1
gene id: 9940:CNTNAP1
uniprot id: W5NYP3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

9940:GHRHR
gene id: 9940:GHRHR
uniprot id: Q9BDI0
names: Subcellular Location Annotation
messages: Membrane

9940:CTSH
gene id: 9940:CTSH
uniprot id: W5PZ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9940:TTR
gene id: 9940:TTR
uniprot id: A0A6P7DCR0
uniprot id: P12303
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the transthyretin family.
messages: Highly expressed in the choroid plexus.
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4 (By similarity).
messages: Homotetramer. Dimer of dimers. In the homotetramer, subunits assemble around a central channel that can accommodate two ligand molecules. Interacts with RBP4.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity).
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

9940:PSMA2
gene id: 9940:PSMA2
uniprot id: W5Q7C7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9940:EIF3G
gene id: 9940:EIF3G
uniprot id: A0A6P3E5J0
uniprot id: W5Q0G0
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:BABAM2
gene id: 9940:BABAM2
uniprot id: A0A6P3E738
uniprot id: A0A6P7DVI7
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EXOC1
gene id: 9940:EXOC1
uniprot id: W5NWG9
uniprot id: W5NWH2
names: Similarity
messages: Belongs to the SEC3 family.

9940:CHRNB4
gene id: 9940:CHRNB4
uniprot id: W5NST5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:FAM229A
gene id: 9940:FAM229A
uniprot id: W5QIF8
names: Similarity
messages: Belongs to the FAM229 family.

9940:ITGB1BP1
gene id: 9940:ITGB1BP1
uniprot id: A0A6P3E701
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TADA2A
gene id: 9940:TADA2A
uniprot id: A0A6P3THP5
uniprot id: A0A6P3YJZ2
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LSM7
gene id: 9940:LSM7
uniprot id: A0A6P3E4L6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LSM8
gene id: 9940:LSM8
uniprot id: W5Q9A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9940:HPDL
gene id: 9940:HPDL
uniprot id: A0A6P3E3W0
uniprot id: W5PJH3
names: Caution
names: Similarity
messages: Belongs to the 4HPPD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GRIA1
gene id: 9940:GRIA1
uniprot id: W5PI48
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9940:NDUFC1
gene id: 9940:NDUFC1
uniprot id: A0A6P3EDV0
uniprot id: A0A835ZSA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:WDR48
gene id: 9940:WDR48
uniprot id: W5NUX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

9940:KITLG
gene id: 9940:KITLG
uniprot id: A0A836A7Q3
uniprot id: G8Z9W4
uniprot id: G8Z9W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: filopodium
messages: lamellipodium

9940:LOC101117120
gene id: 9940:LOC101117120
uniprot id: A0A836A542
uniprot id: W5P2W9
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119706
gene id: 9940:LOC101119706
uniprot id: A0A6P3E2G5
uniprot id: W5PH35
names: Caution
names: Similarity
messages: Belongs to the cytochrome P450 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KRI1
gene id: 9940:KRI1
uniprot id: A0A6P3EDK9
names: Caution
names: Similarity
messages: Belongs to the KRI1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SCAMP2
gene id: 9940:SCAMP2
uniprot id: A0A6P3EIA8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OSTC
gene id: 9940:OSTC
uniprot id: A0A6P3EA62
uniprot id: W5PD29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DOK4
gene id: 9940:DOK4
uniprot id: A0A6P3EFE5
uniprot id: W5NQ95
names: Caution
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RAB3C
gene id: 9940:RAB3C
uniprot id: A0A6P3T9Z4
uniprot id: W5PBD0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX50
gene id: 9940:DDX50
uniprot id: W5P5E9
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX21/DDX50 subfamily.

9940:PPP2CB
gene id: 9940:PPP2CB
uniprot id: W5NPI8
names: Similarity
messages: Belongs to the PPP phosphatase family.

9940:RO60
gene id: 9940:RO60
uniprot id: W5PI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

9940:HERPUD2
gene id: 9940:HERPUD2
uniprot id: A0A6P3YKZ0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UBE2E2
gene id: 9940:UBE2E2
uniprot id: B3VSC4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:ADD2
gene id: 9940:ADD2
uniprot id: W5PNH0
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9940:HPGDS
gene id: 9940:HPGDS
uniprot id: A0A6P3E5C4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BCKDHA
gene id: 9940:BCKDHA
uniprot id: A0A6P9FQE0
uniprot id: B2LSM3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:G3BP2
gene id: 9940:G3BP2
uniprot id: A0A6P7E6Z8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LEAP2
gene id: 9940:LEAP2
uniprot id: W5PUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LEAP2 family.
messages: Has an antimicrobial activity.
messages: Secreted

9940:TNMD
gene id: 9940:TNMD
uniprot id: W5NWC1
names: Similarity
messages: Belongs to the chondromodulin-1 family.

9940:DLST
gene id: 9940:DLST
uniprot id: W5NTS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

9940:OSBPL9
gene id: 9940:OSBPL9
uniprot id: A0A6P3TCP2
uniprot id: W5P3W6
names: Caution
names: Similarity
messages: Belongs to the OSBP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CDK2
gene id: 9940:CDK2
uniprot id: A0A6P9FQI2
uniprot id: B7U171
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TMEM218
gene id: 9940:TMEM218
uniprot id: W5PNU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

9940:EXOSC1
gene id: 9940:EXOSC1
uniprot id: A0A6P3EFR0
uniprot id: W5PKA0
names: Caution
names: Subcellular Location Annotation
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AIG1
gene id: 9940:AIG1
uniprot id: A0A6P3EG26
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP1R16B
gene id: 9940:PPP1R16B
uniprot id: A0A6P3EBY8
uniprot id: A0A6P7EP96
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HLF
gene id: 9940:HLF
uniprot id: A0A6P9FQH9
uniprot id: B6CM53
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CKM
gene id: 9940:CKM
uniprot id: A0A6P3TVY2
uniprot id: W5PJ69
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCL26
gene id: 9940:CCL26
uniprot id: A0A6P3EE98
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPS18B
gene id: 9940:MRPS18B
uniprot id: W5PSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family. Mitochondrion-specific ribosomal protein mS40 subfamily.
messages: Mitochondrion

9940:LRRC23
gene id: 9940:LRRC23
uniprot id: A0A6P3E3H7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC24A4
gene id: 9940:SLC24A4
uniprot id: W5PTW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9940:THRA
gene id: 9940:THRA
uniprot id: Q28570
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Binds DNA as a dimer; homodimer and heterodimer with RXRB. Interacts with NCOA3 and NCOA6 coactivators, leading to a strong increase of transcription of target genes. Probably interacts with SFPQ. Interacts with C1D. Interacts with AKAP13. Interacts with TP53INP2. Interacts with PER2 (By similarity). Interacts with TACC1. The interaction with isoform alpha-1, but not alpha-2, is decreased in the presence of thyroid hormone T3 (By similarity).
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Does not bind thyroid hormone T3.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

9940:LOC101103041
gene id: 9940:LOC101103041
uniprot id: W5NY11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9940:OXGR1
gene id: 9940:OXGR1
uniprot id: A0A836AAP8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATG3
gene id: 9940:ATG3
uniprot id: A0A6P3E6P2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RHOH
gene id: 9940:RHOH
uniprot id: A0A6P3CX22
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMB7
gene id: 9940:PSMB7
uniprot id: W5PVU5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.

9940:AFG1L
gene id: 9940:AFG1L
uniprot id: W5PM77
names: Similarity
messages: Belongs to the AFG1 ATPase family.

9940:CYP2J
gene id: 9940:CYP2J
uniprot id: Q08ET7
names: Similarity
messages: Belongs to the cytochrome P450 family.

9940:IL34
gene id: 9940:IL34
uniprot id: A0A836A2M4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PDIA6
gene id: 9940:PDIA6
uniprot id: A0A6P3YI89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9940:DDRGK1
gene id: 9940:DDRGK1
uniprot id: A0A6P3E974
names: Caution
names: Similarity
messages: Belongs to the DDRGK1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC115
gene id: 9940:CCDC115
uniprot id: A0A6P7DNW4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A20
gene id: 9940:SLC25A20
uniprot id: B2MVX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:ASB8
gene id: 9940:ASB8
uniprot id: A0A6P3TBD0
names: Function
messages: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9940:LIN28A
gene id: 9940:LIN28A
uniprot id: H6WP37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

9940:UBE2F
gene id: 9940:UBE2F
uniprot id: A0A6P3YIJ2
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9940:TMEM38B
gene id: 9940:TMEM38B
uniprot id: W5PBF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9940:ATP6V0E1
gene id: 9940:ATP6V0E1
uniprot id: A0A6P3EB04
uniprot id: W5P1K7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9940:NXF1
gene id: 9940:NXF1
uniprot id: A0A6P3EK42
uniprot id: W5Q7E7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleoplasm

9940:LOC101115480
gene id: 9940:LOC101115480
uniprot id: A0A6P3EDA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLS1
gene id: 9940:PLS1
uniprot id: A0A836AQG3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLIN5
gene id: 9940:PLIN5
uniprot id: B0FJL7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the perilipin family.
messages: Cytoplasm
messages: Homooligomer. Interacts with PNPLA2; prevents interaction of PNPLA2 with ABHD5. Interacts with ABHD5; targets ABHD5 to lipid droplets and promotes interaction of ABHD5 with PNPLA2. Interacts with LIPE (By similarity).
messages: Lipid droplet
messages: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).
messages: Mitochondrion
messages: Phosphorylated by PKA. Phosphorylated on serine in skeletal muscle at rest or upon lipolytic stimulation (By similarity).

9940:CYTL1
gene id: 9940:CYTL1
uniprot id: A0A6P3EAM2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYD88
gene id: 9940:MYD88
uniprot id: C8BKC7
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Upon TLR8 activation by GU-rich single-stranded RNA (GU-rich RNA) derived from viruses, induces IL1B release through NLRP3 inflammasome activation (By similarity). MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine (By similarity).
messages: Cytoplasm
messages: Detecetd in mesenteric lymph node, prescapular lymph node, lymphocytes, lung, kidney, skin and urinary bladder.
messages: Homodimer. Also forms heterodimers with TIRAP. Binds to TLR2, TLR4, IRAK1, IRAK2 and IRAK4 via their respective TIR domains. Interacts with IL18R1. Interacts with BMX, IL1RL1, IKBKE and IRF7. Interacts with LRRFIP1 and LRRFIP2; this interaction positively regulates Toll-like receptor (TLR) signaling in response to agonist. Interacts with FLII. LRRFIP1 and LRRFIP2 compete with FLII for MYD88-binding. Interacts with IRF1. Upon IL1B treatment, forms a complex with PELI1, IRAK1, IRAK4 and TRAF6; this complex recruits MAP3K7/TAK1, TAB1 and TAB2 to mediate NF-kappa-B activation. Direct binding of SMAD6 to PELI1 prevents the complex formation and hence negatively regulates IL1R-TLR signaling and eventually NF-kappa-B-mediated gene expression. May interact with PIK3AP1. Interacts (via TIR domain) with DHX9 (via H2A and OB-fold regions); this interaction is direct. Interacts with OTUD4 deubiquitinase; the interaction is direct.
messages: Nucleus
messages: The intermediate domain (ID) is required for the phosphorylation and activation of IRAK.
messages: Ubiquitinated; undergoes 'Lys-63'-linked polyubiquitination. OTUD4 specifically hydrolyzes 'Lys-63'-linked polyubiquitinated MYD88.

9940:CA1
gene id: 9940:CA1
uniprot id: P48282
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Catalyzes the reversible hydration of carbon dioxide.
messages: Cytoplasm
messages: Inhibited by acetazolamide.

9940:BRMS1
gene id: 9940:BRMS1
uniprot id: A0A6P7D8I5
names: Subcellular Location Annotation
messages: Nucleus

9940:TAL2
gene id: 9940:TAL2
uniprot id: A0A6P3YJ38
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PMS2
gene id: 9940:PMS2
uniprot id: A0A6P3ELY5
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9940:DLX1
gene id: 9940:DLX1
uniprot id: W5NTM4
names: Subcellular Location Annotation
messages: Nucleus

9940:CDKN1B
gene id: 9940:CDKN1B
uniprot id: W5QI61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

9940:PRXL2A
gene id: 9940:PRXL2A
uniprot id: A0A6P7DHJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin-like PRXL2 family. PRXL2A subfamily.
messages: Cytoplasm

9940:GNG5
gene id: 9940:GNG5
uniprot id: A0A6P3YEX7
uniprot id: W5PWW2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRPF4
gene id: 9940:PRPF4
uniprot id: A0A6P3E8S1
names: Caution
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNX2
gene id: 9940:SNX2
uniprot id: A0A6P3YHY5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: lamellipodium

9940:DDX6
gene id: 9940:DDX6
uniprot id: W5PPA7
names: Similarity
messages: Belongs to the DEAD box helicase family.

9940:S100B
gene id: 9940:S100B
uniprot id: A0A6P3E0L8
uniprot id: W5PVB6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

9940:CD180
gene id: 9940:CD180
uniprot id: W5P7C7
names: Similarity
messages: Belongs to the Toll-like receptor family.

9940:LOC101116076
gene id: 9940:LOC101116076
uniprot id: A0A6P3EF16
names: Caution
names: Similarity
messages: Belongs to the CBP3 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:BEGAIN
gene id: 9940:BEGAIN
uniprot id: Q6R6L0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DLG4 and DLGAP1 and forms a ternary complex.
messages: May sustain the structure of the postsynaptic density (PSD).
messages: Membrane

9940:DTNBP1
gene id: 9940:DTNBP1
uniprot id: B2LU24
names: Similarity
messages: Belongs to the dysbindin family.

9940:TVP23B
gene id: 9940:TVP23B
uniprot id: A0A836CY07
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PLA2G12A
gene id: 9940:PLA2G12A
uniprot id: W5P6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Secreted

9940:LGALS12
gene id: 9940:LGALS12
uniprot id: A0A836CRP2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SIRT3
gene id: 9940:SIRT3
uniprot id: A0A6P3EQQ2
uniprot id: W5PGB0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.
messages: NAD-dependent protein deacetylase.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZDHHC7
gene id: 9940:ZDHHC7
uniprot id: C7BDW1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9940:TSPAN9
gene id: 9940:TSPAN9
uniprot id: A0A836D5M8
uniprot id: B3VSC2
names: Caution
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Found in a complex with GP6.
messages: Glycosylated.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120236
gene id: 9940:LOC101120236
uniprot id: A0A6P7EG13
uniprot id: W5PD15
names: Caution
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9940:NRM
gene id: 9940:NRM
uniprot id: W5PQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nurim family.
messages: Membrane
messages: Nucleus inner membrane

9940:ANKRD22
gene id: 9940:ANKRD22
uniprot id: A0A6P3EFP3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ORC1
gene id: 9940:ORC1
uniprot id: W5P5G8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

9940:ZBTB9
gene id: 9940:ZBTB9
uniprot id: A0A6P3ECH1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101119853
gene id: 9940:LOC101119853
uniprot id: A0A6P3TDT2
uniprot id: W5PX83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9940:PDE1B
gene id: 9940:PDE1B
uniprot id: W5Q3K8
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9940:RFX6
gene id: 9940:RFX6
uniprot id: A0A836ACZ3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:INTS13
gene id: 9940:INTS13
uniprot id: A0A836ABB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TAGLN2
gene id: 9940:TAGLN2
uniprot id: A0A836DA07
names: Caution
names: Similarity
messages: Belongs to the calponin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CMC2
gene id: 9940:CMC2
uniprot id: W5PE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

9940:RPL29
gene id: 9940:RPL29
uniprot id: W5P900
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

9940:LOC101105617
gene id: 9940:LOC101105617
uniprot id: A0A6P3E6L0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TTC27
gene id: 9940:TTC27
uniprot id: W5PL13
names: Similarity
messages: Belongs to the TTC27 family.

9940:VNN1
gene id: 9940:VNN1
uniprot id: A0A6P7EAS8
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9940:C19H3orf14
gene id: 9940:C19H3orf14
uniprot id: A0A6P3EPE2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RDH11
gene id: 9940:RDH11
uniprot id: A0A6P3TR50
uniprot id: W5QJ56
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SIRT4
gene id: 9940:SIRT4
uniprot id: C5IWT2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to some authors, ADP-ribosyltransferase activity of sirtuins may be an inefficient side reaction of the deacetylase activity and may not be physiologically relevant.
messages: Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion.
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Interacts with GLUD1, IDE and SLC25A5. Interacts with DLAT and PDHX.
messages: Mitochondrion matrix

9940:DCLRE1A
gene id: 9940:DCLRE1A
uniprot id: W5PV68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9940:RAB38
gene id: 9940:RAB38
uniprot id: A0A6P3EF90
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: The small GTPases Rab are key regulators in vesicle trafficking.

9940:SLC25A13
gene id: 9940:SLC25A13
uniprot id: A0A6P3E4H8
uniprot id: W5P1S3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP7A
gene id: 9940:ATP7A
uniprot id: W5QAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

9940:ADAM9
gene id: 9940:ADAM9
uniprot id: A0A6P3ES81
uniprot id: W5NUR4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCR10
gene id: 9940:CCR10
uniprot id: A0A6P3CWN4
uniprot id: Q1WLP8
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ERP27
gene id: 9940:ERP27
uniprot id: A0A6P3E3S1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMAD5
gene id: 9940:SMAD5
uniprot id: W5PZY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9940:MYO6
gene id: 9940:MYO6
uniprot id: W5P9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: clathrin-coated pit
messages: clathrin-coated vesicle
messages: filopodium
messages: microvillus

9940:TRMT10B
gene id: 9940:TRMT10B
uniprot id: A0A6P3E819
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NPPA
gene id: 9940:NPPA
uniprot id: O46540
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the natriuretic peptide family.
messages: Cell projection
messages: Cleavage by MME initiates degradation of the factor and thereby regulates its activity. Degradation by IDE results in reduced activation of NPR1 (in vitro). During IDE degradation, the resulting products can temporarily stimulate NPR2 to produce cGMP, before the fragments are completely degraded and inactivated by IDE (in vitro).
messages: Degraded by IDE.
messages: Homodimer; disulfide-linked antiparallel dimer.
messages: Hormone produced in the kidneys that appears to be important for maintaining cardio-renal homeostasis. Mediates vasodilation, natriuresis and diuresis primarily in the renal system, in order to maintain the extracellular fluid volume and control the fluid-electrolyte balance. Specifically binds and stimulates cGMP production by renal transmembrane receptors, likely NPR1. Urodilatin not ANP, may be the natriuretic peptide responsible for the regulation of sodium and water homeostasis in the kidney.
messages: Hormone that plays a key role in mediating cardio-renal homeostasis, and is involved in vascular remodeling and regulating energy metabolism (By similarity). Acts by specifically binding and stimulating NPR1 to produce cGMP, which in turn activates effector proteins, such as PRKG1, that drive various biological responses (By similarity). Regulates vasodilation, natriuresis, diuresis and aldosterone synthesis and is therefore essential for regulating blood pressure, controlling the extracellular fluid volume and maintaining the fluid-electrolyte balance (By similarity). Also involved in inhibiting cardiac remodeling and cardiac hypertrophy by inducing cardiomyocyte apoptosis and attenuating the growth of cardiomyocytes and fibroblasts (By similarity). Plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus, and thus prevents pregnancy-induced hypertension (By similarity). In adipose tissue, acts in various cGMP- and PKG-dependent pathways to regulate lipid metabolism and energy homeostasis (By similarity). This includes up-regulating lipid metabolism and mitochondrial oxygen utilization by activating the AMP-activated protein kinase (AMPK), and increasing energy expenditure by acting via MAPK11 to promote the UCP1-dependent thermogenesis of brown adipose tissue (By similarity). Binds the clearance receptor NPR3 which removes the hormone from circulation (By similarity).
messages: May have a role in cardio-renal homeostasis through regulation of diuresis and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. May have a role in potassium excretion but not sodium excretion (natriuresis). Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis and in vitro, vasodilates renal artery strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal and vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, selectively vasodilates intestinal smooth muscle but not vascular smooth muscle strips.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, and vasodilation. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase. However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis. Appears to bind to specific receptors that are distinct from the receptors bound by the atrial natriuretic and long-acting natriuretic peptides. Possibly functions in protein excretion in urine by maintaining the integrity of the proximal tubules and enhancing protein excretion by decreasing proximal tubular protein reabsorption.
messages: May have a role in cardio-renal homeostasis through regulation of natriuresis, diuresis, vasodilation, and inhibiting aldosterone synthesis. In vitro, promotes the production of cGMP and induces vasodilation. May promote natriuresis, at least in part, by enhancing prostaglandin E2 synthesis resulting in the inhibition of renal Na+-K+-ATPase (By similarity). However reports on the involvement of this peptide in mammal blood volume and blood pressure homeostasis are conflicting; according to a report, in vivo it is not sufficient to activate cGMP and does not inhibit collecting duct transport nor effect diuresis and natriuresis (By similarity). Appears to bind to specific receptors that are distinct from the receptors bound by atrial natriuretic peptide and vessel dilator. Possibly enhances protein excretion in urine by decreasing proximal tubular protein reabsorption (By similarity).
messages: May have a role in cardio-renal homeostasis through regulation of regulation of natriuresis and vasodilation. In vivo promotes natriuresis. In vitro, vasodilates intestinal smooth muscle but not smooth muscle strips.
messages: Perikaryon
messages: Phosphorylation on Ser-128 decreases vasorelaxant activity.
messages: Results concerning the involvement of this peptide in blood volume and blood pressure homeostasis are conflicting. Several studies utilising in vitro and heterologous expression systems show that it is able to activate cGMP and promote vasodilation and natriuresis (By similarity). However, a heterologous and in vivo expression study in rat found that it is not sufficient to induce any diuretic, natriuretic, nor hypotensive responses, and is unable to bind NPR1 nor increase guanylyl cyclase activity (By similarity).
messages: Results concerning the involvement of this peptide in blood volume and blood pressure homeostasis are conflicting. Several studies utilising in vitro and heterologous expression systems show that it is able to activate cGMP and promote vasodilation and natriuresis (By similarity). However, an in vivo study in rat found that it is not sufficient to induce any diuretic, natriuretic, nor hypotensive responses, and is unable to bind NPR1 nor increase guanylyl cyclase activity (By similarity).
messages: Secreted
messages: The precursor molecule is proteolytically cleaved by CORIN at Arg-122 to produce the atrial natriuretic peptide (By similarity). Undergoes further proteolytic cleavage by unknown proteases to give rise to long-acting natriuretic peptide, vessel dilator and kaliuretic peptide (By similarity). Additional processing gives rise to the auriculin and atriopeptin peptides (By similarity). In the kidneys, alternative processing by an unknown protease results in the peptide urodilatin (By similarity).

9940:CNN1
gene id: 9940:CNN1
uniprot id: A0A836D2P7
uniprot id: Q7YRL2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calponin family.
messages: Part of cGMP kinase signaling complex at least composed of ACTA2/alpha-actin, CNN1/calponin H1, PLN/phospholamban, PRKG1 and ITPR1.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

9940:MOSPD2
gene id: 9940:MOSPD2
uniprot id: A0A6P3ES92
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CAMK1
gene id: 9940:CAMK1
uniprot id: A0A6P3EPC0
uniprot id: W5P841
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101109345
gene id: 9940:LOC101109345
uniprot id: W5PVL1
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

9940:UBQLN1
gene id: 9940:UBQLN1
uniprot id: A0A6P3CWX8
uniprot id: C5ISB7
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: autophagosome

9940:LOC101106199
gene id: 9940:LOC101106199
uniprot id: A0A835ZT30
uniprot id: P02083
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGPAT1
gene id: 9940:AGPAT1
uniprot id: A0A6P3TEE2
uniprot id: A0A6P7D766
uniprot id: Q95JH0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: Endoplasmic reticulum membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CACNB4
gene id: 9940:CACNB4
uniprot id: W5PF31
names: Similarity
messages: Belongs to the calcium channel beta subunit family.

9940:UBE2E3
gene id: 9940:UBE2E3
uniprot id: A0A835ZIM5
names: Caution
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FOS
gene id: 9940:FOS
uniprot id: A0A6P3CXM5
uniprot id: C8BKC1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Fos subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:SMIM15
gene id: 9940:SMIM15
uniprot id: W5P5S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM15 family.
messages: Membrane

9940:LOC443456
gene id: 9940:LOC443456
uniprot id: A0A6P3DZB2
uniprot id: W5QET6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SC5
gene id: 9940:SC5
uniprot id: P49929
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Broad spectrum bactericidal agent.
messages: Secreted

9940:ITGA4
gene id: 9940:ITGA4
uniprot id: W5Q5Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9940:CCS
gene id: 9940:CCS
uniprot id: W5PBW4
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
messages: Nucleus

9940:ITK
gene id: 9940:ITK
uniprot id: A0A6P3EEE1
uniprot id: W5PNG3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPS8
gene id: 9940:RPS8
uniprot id: A0A6P3CXM0
uniprot id: K4P1S8
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FAM120C
gene id: 9940:FAM120C
uniprot id: A0A6P3ESD9
uniprot id: W5P9N6
names: Caution
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PPP2R2A
gene id: 9940:PPP2R2A
uniprot id: A0A6P3YFU3
uniprot id: A0A8K1PH10
names: Caution
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DYNC2LI1
gene id: 9940:DYNC2LI1
uniprot id: W5PA46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

9940:PDGFRA
gene id: 9940:PDGFRA
uniprot id: W5QCN4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

9940:GCK
gene id: 9940:GCK
uniprot id: M1TCR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9940:TM4SF5
gene id: 9940:TM4SF5
uniprot id: A0A6P3EH35
uniprot id: W5PB58
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAP1LC3B
gene id: 9940:MAP1LC3B
uniprot id: A0A6P3EJC5
uniprot id: W5PQI9
names: Caution
names: Similarity
messages: Belongs to the ATG8 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105614854
gene id: 9940:LOC105614854
uniprot id: A0A6P3TQP7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LHFPL4
gene id: 9940:LHFPL4
uniprot id: W5PA40
names: Subcellular Location Annotation
messages: Membrane

9940:THNSL1
gene id: 9940:THNSL1
uniprot id: A0A835ZUD3
names: Caution
names: Similarity
messages: Belongs to the threonine synthase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STMN4
gene id: 9940:STMN4
uniprot id: W5PJ20
names: Similarity
messages: Belongs to the stathmin family.

9940:CNRIP1
gene id: 9940:CNRIP1
uniprot id: A0A6P3E2J1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CNRIP family.
messages: Interacts with the cannabinoid receptor CNR1 (via C-terminus). Does not interact with cannabinoid receptor CNR2.
messages: Suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SFXN4
gene id: 9940:SFXN4
uniprot id: W5NU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

9940:SSR2
gene id: 9940:SSR2
uniprot id: W5P572
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9940:CPLX3
gene id: 9940:CPLX3
uniprot id: W5NYR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9940:OGFOD2
gene id: 9940:OGFOD2
uniprot id: A0A6P3EHT7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PSMD12
gene id: 9940:PSMD12
uniprot id: A0A6P3EHN2
uniprot id: W5Q2N2
names: Caution
names: Similarity
messages: Belongs to the proteasome subunit p55 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SETD9
gene id: 9940:SETD9
uniprot id: A0A6P3ENA4
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDPGP1
gene id: 9940:GDPGP1
uniprot id: W5Q7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDPGP1 family.
messages: Cytoplasm
messages: Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.

9940:GSTA1-1
gene id: 9940:GSTA1-1
uniprot id: W5PZE4
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9940:MME
gene id: 9940:MME
uniprot id: A0A6P3T810
uniprot id: W5NZL3
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPNE1
gene id: 9940:CPNE1
uniprot id: C5ISA8
names: Similarity
messages: Belongs to the copine family.

9940:LOC101114857
gene id: 9940:LOC101114857
uniprot id: A0A6P3TQL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADIPOQ
gene id: 9940:ADIPOQ
uniprot id: A0A6P3CYL5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPF1
gene id: 9940:RPF1
uniprot id: A0A836AI62
uniprot id: W5PWN9
names: Caution
names: Subcellular Location Annotation
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:LOC101117184
gene id: 9940:LOC101117184
uniprot id: P67982
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallothionein superfamily. Type 1 family.
messages: Class I metallothioneins contain 2 metal-binding domains: four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.
messages: Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.
messages: Monomer.

9940:IL6
gene id: 9940:IL6
uniprot id: B7TXY8
uniprot id: P29455
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability. Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF. Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance (By similarity). 'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis. Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand (By similarity). Also acts as a myokine (By similarity). Plays a protective role during liver injury, being required for maintenance of tissue regeneration (By similarity). Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection (By similarity). Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration (By similarity).
messages: Belongs to the IL-6 superfamily.
messages: Component of a hexamer of two molecules each of IL6, IL6R and IL6ST; first binds to IL6R to associate with the signaling subunit IL6ST. Interacts with IL6R (via the N-terminal ectodomain); this interaction may be affected by IL6R-binding with SORL1, hence decreasing IL6 cis signaling. Interacts with SORL1 (via the N-terminal ectodomain); this interaction leads to IL6 internalization and lysosomal degradation. May form a trimeric complex with the soluble SORL1 ectodomain and soluble IL6R receptor; this interaction might stabilize circulating IL6, hence promoting IL6 trans signaling.
messages: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells (By similarity).
messages: IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury (By similarity). In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.
messages: Secreted

9940:RPTOR
gene id: 9940:RPTOR
uniprot id: A0A6P3EHP9
uniprot id: W5NQQ5
names: Caution
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116979
gene id: 9940:LOC101116979
uniprot id: W5QD87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101103421
gene id: 9940:LOC101103421
uniprot id: A0A6P3EKM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZMPSTE24
gene id: 9940:ZMPSTE24
uniprot id: A0A6P3E3U0
uniprot id: W5QG63
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101120602
gene id: 9940:LOC101120602
uniprot id: W5P9D6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:PYGB
gene id: 9940:PYGB
uniprot id: Q5MIB6
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Activity of phosphorylase is controlled both by allosteric means (through the non-covalent binding of metabolites) and by covalent modification. Thus AMP allosterically activates, whereas ATP, ADP, and glucose-6-phosphate allosterically inhibit, phosphorylase B (By similarity).
messages: Belongs to the glycogen phosphorylase family.
messages: Glycogen phosphorylase that regulates glycogen mobilization. Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
messages: Homodimer. Dimers associate into a tetramer to form the enzymatically active phosphorylase A (By similarity).
messages: Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.

9940:LAMC2
gene id: 9940:LAMC2
uniprot id: E2QBS9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9940:PCNA
gene id: 9940:PCNA
uniprot id: A0A6P3E961
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

9940:LOC101123127
gene id: 9940:LOC101123127
uniprot id: A0A836AE67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MAT2A
gene id: 9940:MAT2A
uniprot id: W5QH42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9940:LOC101123171
gene id: 9940:LOC101123171
uniprot id: W5QHG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:LOC101115410
gene id: 9940:LOC101115410
uniprot id: A0A6P3EP25
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL20
gene id: 9940:MRPL20
uniprot id: A0A6P3EJR9
uniprot id: W5P016
names: Caution
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104321
gene id: 9940:LOC101104321
uniprot id: A0A6P3TIJ5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EDNRA
gene id: 9940:EDNRA
uniprot id: Q95L55
uniprot id: W5PE99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA sub-subfamily.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3 (By similarity).
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

9940:GPCPD1
gene id: 9940:GPCPD1
uniprot id: A0A835ZWC9
names: Caution
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SIKE1
gene id: 9940:SIKE1
uniprot id: W5QFN6
names: Similarity
messages: Belongs to the SIKE family.

9940:API5
gene id: 9940:API5
uniprot id: A0A6P3EML8
names: Caution
names: Similarity
messages: Belongs to the API5 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NDUFB5
gene id: 9940:NDUFB5
uniprot id: A0A8N7XJ68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSCB
gene id: 9940:HSCB
uniprot id: W5NXH4
names: Similarity
messages: Belongs to the HscB family.

9940:GH
gene id: 9940:GH
uniprot id: P67930
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.
messages: Secreted

9940:FSHR
gene id: 9940:FSHR
uniprot id: P35379
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. The activity of isoform FSH-R1 is mediated by G proteins which activate adenylate cyclase (PubMed:10527886, PubMed:9364440). Isoform FSH-R2 and isoform FSH-R3 also bind FSH, but this does not result in activation of adenylate cyclase (PubMed:10527886, PubMed:9364440). Isoform FSH-R3 may be involved in calcium signaling (PubMed:10527886). Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways (By similarity).
messages: Homotrimer. Functions as a homotrimer binding the FSH hormone heterodimer composed of CGA and FSHB (By similarity). Interacts with ARRB2 (By similarity). Interacts with APPL2; interaction is independent of follicle stimulating hormone stimulation (By similarity).
messages: Isoform FSH-R3 is expressed in ovary and testis, but not in kidney (at protein level).
messages: N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone.
messages: Sulfated.

9940:PRRC1
gene id: 9940:PRRC1
uniprot id: W5Q8M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

9940:LOC101102567
gene id: 9940:LOC101102567
uniprot id: A0A6P3E6H3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MCTP1
gene id: 9940:MCTP1
uniprot id: W5Q5V1
names: Subcellular Location Annotation
messages: Membrane

9940:CCDC137
gene id: 9940:CCDC137
uniprot id: A0A6P3EHP5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ATP2B3
gene id: 9940:ATP2B3
uniprot id: W5PCE8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:CCDC86
gene id: 9940:CCDC86
uniprot id: W5Q1V5
names: Subcellular Location Annotation
messages: Nucleus

9940:LRRC8D
gene id: 9940:LRRC8D
uniprot id: W5PKY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9940:SERPINA14
gene id: 9940:SERPINA14
uniprot id: P21814
names: PTM
names: Similarity
names: Tissue Specificity
messages: Belongs to the serpin family. UTMP subfamily.
messages: Glycosylated; carries the so-called mannose 6-phosphate lysosomal recognition marker on its carbohydrate chains.
messages: Secreted by ovine endometrium under the influence of progesterone.

9940:CHEK1
gene id: 9940:CHEK1
uniprot id: W5PPW3
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

9940:MSTO1
gene id: 9940:MSTO1
uniprot id: W5P3D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

9940:LOC101118831
gene id: 9940:LOC101118831
uniprot id: W5QBM0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9940:GALNS
gene id: 9940:GALNS
uniprot id: W5PVT3
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9940:ZBTB39
gene id: 9940:ZBTB39
uniprot id: A0A836D406
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CPQ
gene id: 9940:CPQ
uniprot id: A0A6P3TQK8
uniprot id: A0A6P7EER3
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122359
gene id: 9940:LOC101122359
uniprot id: A0A6P3E5P1
uniprot id: W5P446
names: Caution
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ITPR2
gene id: 9940:ITPR2
uniprot id: A0A6P3E860
uniprot id: W5QF81
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MFSD9
gene id: 9940:MFSD9
uniprot id: A0A836D4T1
uniprot id: W5PU30
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DNASE2
gene id: 9940:DNASE2
uniprot id: A0A6P3E4H2
names: Caution
names: Similarity
messages: Belongs to the DNase II family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101122904
gene id: 9940:LOC101122904
uniprot id: A0A6P3TND1
uniprot id: W5PV69
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MSMB
gene id: 9940:MSMB
uniprot id: A0A6P3EGV0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MGAT2
gene id: 9940:MGAT2
uniprot id: W5NRR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 16 (GT16) protein family.
messages: Golgi apparatus membrane
messages: Membrane

9940:KCNS2
gene id: 9940:KCNS2
uniprot id: A0A6P3YN21
uniprot id: W5PZ34
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:GCHFR
gene id: 9940:GCHFR
uniprot id: A0A6P3E624
uniprot id: W5QGB6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:CRYZ
gene id: 9940:CRYZ
uniprot id: A0A6P3DYF0
uniprot id: W5PSF8
names: Caution
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104234
gene id: 9940:LOC101104234
uniprot id: A0A6P3TE17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:MANEA
gene id: 9940:MANEA
uniprot id: W5PRE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9940:RIOK3
gene id: 9940:RIOK3
uniprot id: W5PDX2
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.
messages: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.

9940:ITGB6
gene id: 9940:ITGB6
uniprot id: B0FYY3
uniprot id: Q863C4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the integrin beta chain family.
messages: Heterodimer of an alpha and a beta subunit (By similarity). Interacts with FLNB. Interacts with HAX1. ITGAV:ITGB6 interacts with FBN1 (By similarity). ITGAV:ITGB6 interacts with TGFB1 (By similarity).
messages: Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (By similarity).
messages: Membrane
messages: focal adhesion

9940:CCL28
gene id: 9940:CCL28
uniprot id: A6N8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9940:LPL
gene id: 9940:LPL
uniprot id: Q29524
names: Activity Regulation
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with GPIHBP1 with 1:1 stoichiometry (By similarity). Interacts with APOC2; the interaction activates LPL activity in the presence of lipids (By similarity). Interaction with heparan sulfate proteoglycans is required to protect LPL against loss of activity. Associates with lipoprotein particles in blood plasma. Interacts with LMF1 and SEL1L; interaction with SEL1L is required to prevent aggregation of newly synthesized LPL in the endoplasmic reticulum (ER), and for normal export of LPL from the ER to the extracellular space (By similarity). Interacts with SORL1; SORL1 acts as a sorting receptor, promoting LPL localization to endosomes and later to lysosomes, leading to degradation of newly synthesized LPL (By similarity).
messages: Key enzyme in triglyceride metabolism (By similarity). Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage (By similarity). Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity (By similarity). Mediates margination of triglyceride-rich lipoprotein particles in capillaries (By similarity). Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans (By similarity).
messages: Secreted
messages: The apolipoprotein APOC2 acts as a coactivator of LPL activity (By similarity). Ca(2+) binding promotes protein stability and formation of the active homodimer. Interaction with GPIHBP1 protects LPL against inactivation by ANGPTL4 (By similarity).
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

9940:SCNN1G
gene id: 9940:SCNN1G
uniprot id: W5Q558
names: Subcellular Location Annotation
messages: Membrane

9940:PECR
gene id: 9940:PECR
uniprot id: A0A836ADY5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AQP4
gene id: 9940:AQP4
uniprot id: A0A6P3TFZ5
uniprot id: Q866S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9940:LOC101119008
gene id: 9940:LOC101119008
uniprot id: W5PLT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:ENPP6
gene id: 9940:ENPP6
uniprot id: A0A6P3EH01
uniprot id: W5PBV4
names: Caution
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GADD45B
gene id: 9940:GADD45B
uniprot id: A0A6P3ECN5
uniprot id: W5PW26
names: Caution
names: Similarity
messages: Belongs to the GADD45 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:STING1
gene id: 9940:STING1
uniprot id: A0A6P3TE04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STING family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: autophagosome membrane
messages: perinuclear region

9940:KICS2
gene id: 9940:KICS2
uniprot id: A0A6P3E2X9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ADIPOR2
gene id: 9940:ADIPOR2
uniprot id: W5PTD2
uniprot id: W8FSV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9940:LPIN1
gene id: 9940:LPIN1
uniprot id: J9S2T1
names: Similarity
messages: Belongs to the lipin family.

9940:PGD
gene id: 9940:PGD
uniprot id: P00349
names: Function
names: Sequence Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Cytoplasm
messages: Homodimer.
messages: Incorrect CNBR peptide order. Many sequencing errors.

9940:NOP56
gene id: 9940:NOP56
uniprot id: A0A6P3EBR5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:GNL3
gene id: 9940:GNL3
uniprot id: A0A836CU51
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNX11
gene id: 9940:SNX11
uniprot id: W5PBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9940:FGFBP1
gene id: 9940:FGFBP1
uniprot id: W5PDM2
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

9940:MC4R
gene id: 9940:MC4R
uniprot id: B2MV59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

9940:SRP14
gene id: 9940:SRP14
uniprot id: A0A6P3E7K7
uniprot id: B0LRP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SRP14 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
messages: Cytoplasm
messages: Heterodimer with SRP9; binds RNA as heterodimer. Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MYF5
gene id: 9940:MYF5
uniprot id: W5Q0M6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9940:ZUP1
gene id: 9940:ZUP1
uniprot id: W5PH36
names: Similarity
names: Subunit
messages: Belongs to the peptidase C78 family. ZUFSP subfamily.
messages: Interacts with RPA1 and RPA2.

9940:WASHC5
gene id: 9940:WASHC5
uniprot id: A0A6P3YN70
names: Caution
names: Similarity
messages: Belongs to the strumpellin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNOT7
gene id: 9940:CNOT7
uniprot id: A0A6P3ERK4
uniprot id: W5PI55
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPA2
gene id: 9940:RPA2
uniprot id: W5NZ54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

9940:ZDHHC23
gene id: 9940:ZDHHC23
uniprot id: A0A6P3E4W1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9940:LOC101112179
gene id: 9940:LOC101112179
uniprot id: A0A6P3DZT2
uniprot id: W5PAX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HSD17B10
gene id: 9940:HSD17B10
uniprot id: W5PF12
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9940:PLA2G2D
gene id: 9940:PLA2G2D
uniprot id: W5PI86
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9940:DEFB116
gene id: 9940:DEFB116
uniprot id: A0A2V0A0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9940:DBP
gene id: 9940:DBP
uniprot id: A0A6P3CX42
uniprot id: B6CM52
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TPPP3
gene id: 9940:TPPP3
uniprot id: A0A836A0R3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:LOC101115213
gene id: 9940:LOC101115213
uniprot id: A0A6P3EET2
uniprot id: W5QEQ8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
messages: Cytoplasm
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SNRPN
gene id: 9940:SNRPN
uniprot id: W5PH28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP SmB/SmN family.
messages: Nucleus

9940:LOC101122400
gene id: 9940:LOC101122400
uniprot id: A0A836CQV6
uniprot id: W5P1N9
names: Caution
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MX2
gene id: 9940:MX2
uniprot id: Q5I2P5
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: By type I and type III interferons.
messages: Cytoplasm
messages: Interferon-induced dynamin-like GTPase with antiviral activity.
messages: Nucleus

9940:UPK1A
gene id: 9940:UPK1A
uniprot id: W5P4F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9940:AK6
gene id: 9940:AK6
uniprot id: W5P6L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

9940:NDUFB3
gene id: 9940:NDUFB3
uniprot id: A0A6P7DQB1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRDL2
gene id: 9940:CHRDL2
uniprot id: A0A6P3EGN3
uniprot id: W5PL83
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NOSTRIN
gene id: 9940:NOSTRIN
uniprot id: A0A6P3T904
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102223
gene id: 9940:LOC101102223
uniprot id: A0A6P3E3Z9
uniprot id: W5QGM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAPPC6B
gene id: 9940:TRAPPC6B
uniprot id: A0A6P3EBX2
uniprot id: W5PFI1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cis-Golgi network

9940:CD164
gene id: 9940:CD164
uniprot id: A0A6P3EGU1
uniprot id: W5PLD6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SUSD1
gene id: 9940:SUSD1
uniprot id: W5P9C3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:POLR2M
gene id: 9940:POLR2M
uniprot id: W5QI74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRINL1 family.
messages: Nucleus

9940:PA2G4
gene id: 9940:PA2G4
uniprot id: W5PKW0
names: Similarity
messages: Belongs to the peptidase M24 family.

9940:GMPR
gene id: 9940:GMPR
uniprot id: A0A6P3EP35
uniprot id: W5PRM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family. GuaC type 1 subfamily.
messages: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
messages: Homotetramer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101106910
gene id: 9940:LOC101106910
uniprot id: W5NZS5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:ELOC
gene id: 9940:ELOC
uniprot id: A0A836D201
names: Caution
names: Similarity
messages: Belongs to the SKP1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:E2F8
gene id: 9940:E2F8
uniprot id: W5PG88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9940:RGR
gene id: 9940:RGR
uniprot id: W5NPY9
names: Subcellular Location Annotation
messages: Membrane

9940:LOC101121373
gene id: 9940:LOC101121373
uniprot id: W5P9H2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:SPX
gene id: 9940:SPX
uniprot id: U5YRS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

9940:LOC101119852
gene id: 9940:LOC101119852
uniprot id: A0A835ZWP3
names: Caution
names: Subcellular Location Annotation
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SEC62
gene id: 9940:SEC62
uniprot id: A0A6P3E0D5
uniprot id: W5NQN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101123268
gene id: 9940:LOC101123268
uniprot id: W5PEC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9940:CCNG2
gene id: 9940:CCNG2
uniprot id: A0A6P3EF97
names: Similarity
messages: Belongs to the cyclin family.

9940:LOC101111389
gene id: 9940:LOC101111389
uniprot id: W5P974
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:GNRHR
gene id: 9940:GNRHR
uniprot id: P32237
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

9940:VAMP8
gene id: 9940:VAMP8
uniprot id: A0A6P3E9W7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF185
gene id: 9940:ZNF185
uniprot id: A0A835ZJH2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKAA1
gene id: 9940:PRKAA1
uniprot id: A0A6P3EDP8
uniprot id: W5PHS9
names: Caution
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PTK6
gene id: 9940:PTK6
uniprot id: W5PMR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9940:CNTFR
gene id: 9940:CNTFR
uniprot id: A0A6P7DN59
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 3 subfamily.

9940:VASH1
gene id: 9940:VASH1
uniprot id: A0A836A3U9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL49
gene id: 9940:MRPL49
uniprot id: A0A6P3EQM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SPINK4
gene id: 9940:SPINK4
uniprot id: A0A6P3E124
uniprot id: W5PIF8
names: Caution
names: Subcellular Location Annotation
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HDAC8
gene id: 9940:HDAC8
uniprot id: W5Q8N1
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

9940:ATXN3
gene id: 9940:ATXN3
uniprot id: B3VSB5
names: Subcellular Location Annotation
messages: Nucleus

9940:PIK3CG
gene id: 9940:PIK3CG
uniprot id: A0A836AHH4
names: Caution
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL24
gene id: 9940:RPL24
uniprot id: A0A6P3E7S8
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRNP
gene id: 9940:PRNP
uniprot id: A0A836A7F4
uniprot id: P23907
uniprot id: Q27H92
names: Caution
names: Disease Annotation
names: Domain
names: Function
names: Miscellaneous
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A number of amino acid polymorphism sites that influence scrapie susceptibility and transmission have been described. These are alanine to threonine or valine at codon 136, arginine to histidine at codon 154, and arginine to glutamine, histidine or lysine at codon 171. A number of allelic variants have been described based on the amino acids found at these three positions: VRQ, ARQ, AHQ, TRQ, ARK, ARR and ARH.
messages: Belongs to the prion family.
messages: Cell membrane
messages: Contains an N-terminal region composed of octamer repeats. At low copper concentrations, the sidechains of His residues from three or four repeats contribute to the binding of a single copper ion. Alternatively, a copper ion can be bound by interaction with the sidechain and backbone amide nitrogen of a single His residue. The observed copper binding stoichiometry suggests that two repeat regions cooperate to stabilize the binding of a single copper ion. At higher copper concentrations, each octamer can bind one copper ion by interactions with the His sidechain and Gly backbone atoms. A mixture of binding types may occur, especially in the case of octamer repeat expansion. Copper binding may stabilize the conformation of this region and may promote oligomerization.
messages: Found in high quantity in the brain of humans and animals infected with degenerative neurological diseases such as kuru, Creutzfeldt-Jakob disease (CJD), Gerstmann-Straussler syndrome (GSS), scrapie, bovine spongiform encephalopathy (BSE), transmissible mink encephalopathy (TME), etc.
messages: Golgi apparatus
messages: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains (By similarity).
messages: Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or Zn(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains.
messages: Membrane
messages: Monomer and homodimer. Has a tendency to aggregate into amyloid fibrils containing a cross-beta spine, formed by a steric zipper of superposed beta-strands. Soluble oligomers may represent an intermediate stage on the path to fibril formation. Copper binding may promote oligomerization. Interacts with GRB2, APP, ERI3/PRNPIP and SYN1. Mislocalized cytosolically exposed PrP interacts with MGRN1; this interaction alters MGRN1 subcellular location and causes lysosomal enlargement. Interacts with KIAA1191.
messages: Scrapie is a transmissible neurodegenerative disorder of sheep and goats. Most sheep that contract the disease naturally die between 24 and 50 months of age. The incubation period in sheep depends on the strain(s) of the infecting pathogen, sheep age at exposure, and the sheep genotype. Scrapie can be spread between flockmates, or it can be transmitted from an infected ewe to its lamb.
messages: The alternative prion protein/AltPrP (AC F7VJQ3) and PRNP have no apparent direct functional relation since a mutation that removes the start codon of the AltPrP has no apparent effect on the biology of PRNP (By similarity). In mouse and hamster, the alternative initiation AUG codon is absent and is replaced by a GUG codon.
messages: The normal, monomeric form has a mainly alpha-helical structure. The disease-associated, protease-resistant form forms amyloid fibrils containing a cross-beta spine, formed by a steric zipper of superposed beta-strands. Disease mutations may favor intermolecular contacts via short beta strands, and may thereby trigger oligomerization.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: This protein is produced by a bicistronic gene which also produces the major prion protein/PRNP from an overlapping reading frame.

9940:LOC101104705
gene id: 9940:LOC101104705
uniprot id: W5P530
names: Similarity
messages: Belongs to the serpin family.

9940:LOC101120581
gene id: 9940:LOC101120581
uniprot id: A0A6P3EFQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DDX3X
gene id: 9940:DDX3X
uniprot id: W5NWP4
names: Similarity
messages: Belongs to the DEAD box helicase family.

9940:DNAJC7
gene id: 9940:DNAJC7
uniprot id: A0A6P3EHH7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIN7A
gene id: 9940:LIN7A
uniprot id: W5Q0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

9940:CFAP36
gene id: 9940:CFAP36
uniprot id: A0A6P3E2E2
uniprot id: W5NWA1
names: Caution
names: Similarity
messages: Belongs to the CFAP36 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ST8SIA4
gene id: 9940:ST8SIA4
uniprot id: A0A6P3E696
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GABRG1
gene id: 9940:GABRG1
uniprot id: W5Q189
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9940:TCP11L2
gene id: 9940:TCP11L2
uniprot id: A0A6P3E381
uniprot id: W5Q7F3
names: Caution
names: Similarity
messages: Belongs to the TCP11 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ZNF277
gene id: 9940:ZNF277
uniprot id: W5NX23
names: Similarity
messages: Belongs to the ZNF277 family.

9940:PTGES3L
gene id: 9940:PTGES3L
uniprot id: A0A6P3TX45
names: Caution
names: Similarity
messages: Belongs to the p23/wos2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MMGT1
gene id: 9940:MMGT1
uniprot id: A0A6P3TL79
uniprot id: W5PPL4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins. May be involved in Mg(2+) transport.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:METTL23
gene id: 9940:METTL23
uniprot id: A0A6P3E8B7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C1H1orf189
gene id: 9940:C1H1orf189
uniprot id: A0A6P3E778
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:GDF9
gene id: 9940:GDF9
uniprot id: A0A0M4MFY8
uniprot id: B7U471
uniprot id: O77681
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked (By similarity).
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Ovarian physiology and fertility are controlled by endocrine and paracrine signals. These act in a species-dependent manner and determine the ovulation quota in different mammalian species. While humans, and mammals such as the cow or red deer, normally ovulate only one egg per cycle, other mammals such as mouse and pig can ovulate in excess of ten per cycle. The mechanisms that regulate the species-specific differences in the number of follicles that go onto ovulate during each reproductive cycle are poorly understood. According to PubMed:21970812, mRNA expression levels of GDF9 and BMP15 are tightly coregulated within each species and influence species-specific ovulation-rates.
messages: Phosphorylated; phosphorylation is critical for GDF9 function.
messages: Required for ovarian folliculogenesis.
messages: Secreted

9940:EDN1
gene id: 9940:EDN1
uniprot id: Q9BG76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Also binds the DEAR/FBXW7-AS1 receptor (By similarity).
messages: Secreted

9940:DYNC1LI2
gene id: 9940:DYNC1LI2
uniprot id: A0A6P3EJH4
uniprot id: W5NVS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytoskeleton

9940:SMIM19
gene id: 9940:SMIM19
uniprot id: A0A6P7DIC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

9940:ANXA3
gene id: 9940:ANXA3
uniprot id: A0A6P3YIG9
uniprot id: W5QBI9
names: Caution
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:S100A2
gene id: 9940:S100A2
uniprot id: A0A6P3DZ25
names: Caution
names: Similarity
messages: Belongs to the S-100 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CHRAC1
gene id: 9940:CHRAC1
uniprot id: A0A6P3EHC0
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKRA
gene id: 9940:PRKRA
uniprot id: A0A6P3E673
uniprot id: W5Q7A3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: perinuclear region

9940:TMEM39A
gene id: 9940:TMEM39A
uniprot id: A0A6P3DZL5
uniprot id: W5QEN7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CEP76
gene id: 9940:CEP76
uniprot id: A0A6P3YSP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP76 family.
messages: Centrosomal protein involved in regulation of centriole duplication. Required to limit centriole duplication to once per cell cycle by preventing centriole reduplication.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: centriole

9940:CDH8
gene id: 9940:CDH8
uniprot id: W5NUI5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9940:C3H2orf68
gene id: 9940:C3H2orf68
uniprot id: A0A6P3E771
names: Caution
names: Similarity
messages: Belongs to the UPF0561 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LASP1
gene id: 9940:LASP1
uniprot id: A0A6P3EDE6
uniprot id: W5PK26
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cell cortex
messages: cytoskeleton

9940:GRIA2
gene id: 9940:GRIA2
uniprot id: W5P8A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9940:DHFR
gene id: 9940:DHFR
uniprot id: W5PZI9
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

9940:LOC105616394
gene id: 9940:LOC105616394
uniprot id: W5NPN0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9940:LOC101109530
gene id: 9940:LOC101109530
uniprot id: W5Q9P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:RMND5B
gene id: 9940:RMND5B
uniprot id: A0A836D352
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NT5E
gene id: 9940:NT5E
uniprot id: A0A6P3E6T1
uniprot id: W5PUV3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PRKACA
gene id: 9940:PRKACA
uniprot id: A0A836D2R9
uniprot id: Q9MZD9
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
names: Tissue Specificity
messages: A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. The cAMP-dependent protein kinase catalytic subunit binds PJA2. Both isoforms 1 and 2 forms activate cAMP-sensitive PKAI and PKAII holoenzymes by interacting with regulatory subunit (R) of PKA, PRKAR1A/PKR1 and PRKAR2A/PKR2, respectively. Interacts with NFKB1, NFKB2 and NFKBIA in platelets; these interactions are disrupted by thrombin and collagen. Binds to ABL1 in spermatozoa and with CDC25B in oocytes (By similarity) Interacts with APOBEC3G and AICDA (By similarity). Interacts with RAB13; downstream effector of RAB13 involved in tight junction assembly (By similarity). Found in a complex at least composed of MROH2B, PRKACA isoform 2 and TCP11 (By similarity). Interacts with MROH2B (By similarity). Interacts with HSF1 (By similarity). Isoform 2 interacts with TCP11 (By similarity). Interacts with TBC1D31; in the regulation of OFD1 (By similarity).
messages: Allosterically activated by various compounds, including ATP. Activated by cAMP; the nucleotide acts as a dynamic and allosteric activator by coupling the two lobes of apo PKA, enhancing the enzyme dynamics synchronously and priming it for catalysis.
messages: Asn-3 is partially deaminated to Asp giving rise to 2 major isoelectric variants, called CB and CA respectively.
messages: Autophosphorylated. Phosphorylation is enhanced by vitamin K(2). Phosphorylated on threonine and serine residues. Phosphorylation on Thr-198 is required for full activity (By similarity).
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Isoform 2 is sperm specific.
messages: Membrane
messages: Mitochondrion
messages: Nucleus
messages: Phosphorylated at Tyr-331 by activated receptor tyrosine kinases EGFR and PDGFR; this increases catalytic efficiency.
messages: Phosphorylates a large number of substrates in the cytoplasm and the nucleus (By similarity). Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA, SOX9 and VASP (By similarity). Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. RORA is activated by phosphorylation. Required for glucose-mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts (By similarity). Involved in chondrogenesis by mediating phosphorylation of SOX9 (By similarity). Involved in the regulation of platelets in response to thrombin and collagen; maintains circulating platelets in a resting state by phosphorylating proteins in numerous platelet inhibitory pathways when in complex with NF-kappa-B (NFKB1 and NFKB2) and I-kappa-B-alpha (NFKBIA), but thrombin and collagen disrupt these complexes and free active PRKACA stimulates platelets and leads to platelet aggregation by phosphorylating VASP. RYR2 channel activity is potentiated by phosphorylation in presence of luminal Ca(2+), leading to reduced amplitude and increased frequency of store overload-induced Ca(2+) release (SOICR) characterized by an increased rate of Ca(2+) release and propagation velocity of spontaneous Ca(2+) waves, despite reduced wave amplitude and resting cytosolic Ca(2+). PSMC5/RPT6 activation by phosphorylation stimulates proteasome. Negatively regulates tight junctions (TJs) in ovarian cancer cells via CLDN3 phosphorylation. NFKB1 phosphorylation promotes NF-kappa-B p50-p50 DNA binding. Involved in embryonic development by down-regulating the Hedgehog (Hh) signaling pathway that determines embryo pattern formation and morphogenesis most probably through the regulation of OFD1 in ciliogenesis (By similarity). Prevents meiosis resumption in prophase-arrested oocytes via CDC25B inactivation by phosphorylation (By simil…
messages: Predominant somatic isoform.
messages: Sperm specific.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: acrosome
messages: flagellum

9940:LOC101115172
gene id: 9940:LOC101115172
uniprot id: W5PWD7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9940:CLVS1
gene id: 9940:CLVS1
uniprot id: W5Q4N0
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

9940:ENTPD4
gene id: 9940:ENTPD4
uniprot id: W5PK69
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9940:TAF13
gene id: 9940:TAF13
uniprot id: A0A6P3E476
uniprot id: W5QCJ9
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101116157
gene id: 9940:LOC101116157
uniprot id: A0A6P3E7U8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101117960
gene id: 9940:LOC101117960
uniprot id: W5NXY7
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9940:AFM
gene id: 9940:AFM
uniprot id: W5PXI3
names: Subcellular Location Annotation
messages: Secreted

9940:NAA10
gene id: 9940:NAA10
uniprot id: A0A6P3EHQ2
names: Caution
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYP1A1
gene id: 9940:CYP1A1
uniprot id: P56591
names: Caution
names: Function
names: Induction
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of various endogenous substrates, including fatty acids, steroid hormones and vitamins. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Exhibits high catalytic activity for the formation of hydroxyestrogens from estrone (E1) and 17beta-estradiol (E2), namely 2-hydroxy E1 and E2, as well as D-ring hydroxylated E1 and E2 at the C15alpha and C16alpha positions. Displays different regioselectivities for polyunsaturated fatty acids (PUFA) hydroxylation. Catalyzes the epoxidation of double bonds of certain PUFA. Converts arachidonic acid toward epoxyeicosatrienoic acid (EET) regioisomers, 8,9-, 11,12-, and 14,15-EET, that function as lipid mediators in the vascular system. Displays an absolute stereoselectivity in the epoxidation of eicosapentaenoic acid (EPA) producing the 17(R),18(S) enantiomer. May play an important role in all-trans retinoic acid biosynthesis in extrahepatic tissues. Catalyzes two successive oxidative transformation of all-trans retinol to all-trans retinal and then to the active form all-trans retinoic acid. May also participate in eicosanoids metabolism by converting hydroperoxide species into oxo metabolites (lipoxygenase-like reaction, NADPH-independent).
messages: Belongs to the cytochrome P450 family.
messages: By oxygen; in lung.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Increased expression of this enzyme in lung due to oxygen exposure has been related to hyperoxic injury in microvascular endothelium.
messages: Interacts with cytosolic chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria. Interacts (via mitochondrial targeting signal) with TOMM40 (via N-terminus); this interaction is required for translocation across the mitochondrial outer membrane.
messages: It is uncertain whether Met-1 or Met-4 is the initiator.
messages: Microsome membrane
messages: Mitochondrion inner membrane

9940:RIT1
gene id: 9940:RIT1
uniprot id: A0A836D9Y5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C15H11orf58
gene id: 9940:C15H11orf58
uniprot id: A0A6P3EKA0
uniprot id: W5P6R9
names: Caution
names: Similarity
messages: Belongs to the SMAP family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RIOK1
gene id: 9940:RIOK1
uniprot id: W5Q8K2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9940:MIF
gene id: 9940:MIF
uniprot id: A0A835ZR82
uniprot id: Q1ZZU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MIF family.
messages: Cytoplasm
messages: Homotrimer (By similarity). Interacts with CXCR2 extracellular domain (By similarity). Interacts with the CD74 extracellular domain, USO1, COPS5 and BNIPL (By similarity).
messages: Pro-inflammatory cytokine involved in the innate immune response to bacterial pathogens. The expression of MIF at sites of inflammation suggests a role as mediator in regulating the function of macrophages in host defense. Counteracts the anti-inflammatory activity of glucocorticoids. Has phenylpyruvate tautomerase and dopachrome tautomerase activity (in vitro), but the physiological substrate is not known. It is not clear whether the tautomerase activity has any physiological relevance, and whether it is important for cytokine activity.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD320
gene id: 9940:CD320
uniprot id: W5P0H1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LOC106991327
gene id: 9940:LOC106991327
uniprot id: A0A835ZJ51
uniprot id: K4P217
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AVPR2
gene id: 9940:AVPR2
uniprot id: E3VJQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
messages: Membrane

9940:IGFBP4
gene id: 9940:IGFBP4
uniprot id: B5AZT5
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds IGF2 more than IGF1.
messages: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9940:HMGN4
gene id: 9940:HMGN4
uniprot id: A0A6P7D826
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9940:INSYN1
gene id: 9940:INSYN1
uniprot id: A0A6P3TIA8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCTD13
gene id: 9940:KCTD13
uniprot id: A0A6P3ERM0
uniprot id: W5P4N7
names: Caution
names: Similarity
messages: Belongs to the BACURD family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:FABP4
gene id: 9940:FABP4
uniprot id: A9YUY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9940:CDH19
gene id: 9940:CDH19
uniprot id: W5P4R8
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9940:LOC100134870
gene id: 9940:LOC100134870
uniprot id: A0A0F6YFJ0
uniprot id: P68056
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.
messages: Red blood cells.
messages: This type of beta-C chain is found when anemia has been experimentally produced.

9940:GOLPH3L
gene id: 9940:GOLPH3L
uniprot id: A0A836APL5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: trans-Golgi network membrane

9940:GJB6
gene id: 9940:GJB6
uniprot id: A0A6P3TQW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9940:EXTL2
gene id: 9940:EXTL2
uniprot id: A0A6P3E466
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9940:ABHD14B
gene id: 9940:ABHD14B
uniprot id: A0A6P3EC93
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CZIB
gene id: 9940:CZIB
uniprot id: W5P893
names: Similarity
messages: Belongs to the UPF0587 family.

9940:PUS3
gene id: 9940:PUS3
uniprot id: A0A6P3EFD5
uniprot id: A0A6P3T4D7
names: Caution
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CLRN2
gene id: 9940:CLRN2
uniprot id: A0A836D4T8
uniprot id: W5PL63
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:JOSD1
gene id: 9940:JOSD1
uniprot id: A0A6P3YIU8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PROS1
gene id: 9940:PROS1
uniprot id: W5Q749
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9940:LOC101122597
gene id: 9940:LOC101122597
uniprot id: A0A6P3EDN3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NQO1
gene id: 9940:NQO1
uniprot id: A0A6P3EFH4
uniprot id: W5P093
names: Caution
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:KCNG3
gene id: 9940:KCNG3
uniprot id: W5PC39
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9940:CNFN
gene id: 9940:CNFN
uniprot id: W5PCW7
names: Similarity
messages: Belongs to the cornifelin family.

9940:PGAP1
gene id: 9940:PGAP1
uniprot id: W5Q0I0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI-anchored proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

9940:RAP1GDS1
gene id: 9940:RAP1GDS1
uniprot id: A0A6P3E6Q7
uniprot id: W5Q4B7
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: cytosol

9940:KLHL9
gene id: 9940:KLHL9
uniprot id: A0A6P3E9E2
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:YME1L1
gene id: 9940:YME1L1
uniprot id: A0A6P3E908
names: Caution
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:DR1
gene id: 9940:DR1
uniprot id: A0A6P3E6P8
uniprot id: W5Q5L9
names: Caution
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRIM37
gene id: 9940:TRIM37
uniprot id: A0A6P3TWF5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:UPK1B
gene id: 9940:UPK1B
uniprot id: W5QEI2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
messages: Membrane

9940:GK2
gene id: 9940:GK2
uniprot id: A0A6P3EAI2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SELE
gene id: 9940:SELE
uniprot id: Q95LG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9940:HBM
gene id: 9940:HBM
uniprot id: W5PMN1
names: Similarity
messages: Belongs to the globin family.

9940:RPL32
gene id: 9940:RPL32
uniprot id: A0A6P3ECF2
uniprot id: W5Q000
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AGBL5
gene id: 9940:AGBL5
uniprot id: W5QCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Midbody
messages: Nucleus
messages: cytosol
messages: spindle

9940:LHX4
gene id: 9940:LHX4
uniprot id: W5Q9X8
names: Subcellular Location Annotation
messages: Nucleus

9940:XCL1
gene id: 9940:XCL1
uniprot id: A0A6P9FNA1
uniprot id: Q867A6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.
messages: Secreted
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:AQP11
gene id: 9940:AQP11
uniprot id: W5PB79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Cell membrane
messages: Membrane

9940:GJD2
gene id: 9940:GJD2
uniprot id: W5QFG4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9940:ORMDL3
gene id: 9940:ORMDL3
uniprot id: A0A6P3EDG1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ACSM2B
gene id: 9940:ACSM2B
uniprot id: W5PTC2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9940:ATP2C1
gene id: 9940:ATP2C1
uniprot id: A0A6P3TG41
uniprot id: W5PI39
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: trans-Golgi network membrane

9940:APOO
gene id: 9940:APOO
uniprot id: A0A6P3EEV2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:HADH
gene id: 9940:HADH
uniprot id: W5PEH2
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9940:LOC105608906
gene id: 9940:LOC105608906
uniprot id: W5QEA3
names: Similarity
messages: Belongs to the HSBP1 family.

9940:RNF34
gene id: 9940:RNF34
uniprot id: A0A6P3T6A0
uniprot id: W5PYL3
names: Subcellular Location Annotation
messages: Cell membrane

9940:KBTBD8
gene id: 9940:KBTBD8
uniprot id: A0A6P3EPD8
uniprot id: W5PLA2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: spindle

9940:MRPL18
gene id: 9940:MRPL18
uniprot id: W5P386
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

9940:XPNPEP3
gene id: 9940:XPNPEP3
uniprot id: A0A6P3ECJ5
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CMKLR1
gene id: 9940:CMKLR1
uniprot id: A0A835ZZJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TBCCD1
gene id: 9940:TBCCD1
uniprot id: W5QH62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

9940:METTL4
gene id: 9940:METTL4
uniprot id: H9CJU7
names: Similarity
messages: Belongs to the MT-A70-like family.

9940:LOC101114968
gene id: 9940:LOC101114968
uniprot id: W5P577
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.
messages: Nucleus
messages: kinetochore

9940:GYG1
gene id: 9940:GYG1
uniprot id: A0A6P3YFI9
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101102824
gene id: 9940:LOC101102824
uniprot id: W5PUV7
names: Similarity
messages: Belongs to the TACO1 family.

9940:GTF2H3
gene id: 9940:GTF2H3
uniprot id: A0A6P3EHT2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.
messages: Nucleus
messages: Part of a TFIID-containing RNA polymerase II pre-initiation complex that is composed of TBP and at least GTF2A1, GTF2A2, GTF2E1, GTF2E2, GTF2F1, GTF2H2, GTF2H3, GTF2H4, GTF2H5, GTF2B, TCEA1, ERCC2, ERCC3, TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the 7-subunit TFIIH core complex composed of XPB/ERCC3, XPD/ERCC2, GTF2H1, GTF2H2, GTF2H3, GTF2H4 and GTF2H5, which is active in NER. The core complex associates with the 3-subunit CDK-activating kinase (CAK) module composed of CCNH/cyclin H, CDK7 and MNAT1 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription. Interacts with RARA; the interaction requires prior phosphorylation of RARA on 'Ser-369' which then enhances interaction of RARA with CDK7.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:RPL8
gene id: 9940:RPL8
uniprot id: A0A6P3EG68
uniprot id: W5PSW9
names: Caution
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIP4K2A
gene id: 9940:PIP4K2A
uniprot id: A0A6P3EEK8
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IL13
gene id: 9940:IL13
uniprot id: Q0PW91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-4/IL-13 family.
messages: Interacts with IL13RA2.
messages: Secreted

9940:KRT74
gene id: 9940:KRT74
uniprot id: W5Q659
names: Similarity
messages: Belongs to the intermediate filament family.

9940:KEF53 p13
gene id: 9940:KEF53_p13
uniprot id: A0A0E3JG63
uniprot id: O78747
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Membrane
messages: Mitochondrion inner membrane

9940:SLC9A9
gene id: 9940:SLC9A9
uniprot id: W5P6Y8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

9940:NOL12
gene id: 9940:NOL12
uniprot id: A0A6P3ECI0
uniprot id: W5PX01
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRP17 family.
messages: Interacts with KIAA1191.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: nucleolus

9940:RAB39A
gene id: 9940:RAB39A
uniprot id: A0A6P3ECQ8
uniprot id: W5PMH4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:IRF1
gene id: 9940:IRF1
uniprot id: Q9BG75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9940:KCNA10
gene id: 9940:KCNA10
uniprot id: W5PPM2
names: Subcellular Location Annotation
messages: Membrane

9940:KLF9
gene id: 9940:KLF9
uniprot id: A0A6P3E995
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104364
gene id: 9940:LOC101104364
uniprot id: W5PJ06
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:LOC101114777
gene id: 9940:LOC101114777
uniprot id: W5Q5T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:RPS17
gene id: 9940:RPS17
uniprot id: A0A6P3CXL7
uniprot id: K4P486
names: Caution
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101112257
gene id: 9940:LOC101112257
uniprot id: W5PSL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

9940:TLR7
gene id: 9940:TLR7
uniprot id: B5DC92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

9940:FGGY
gene id: 9940:FGGY
uniprot id: W5PF90
names: Similarity
messages: Belongs to the FGGY kinase family.

9940:PROKR2
gene id: 9940:PROKR2
uniprot id: A0A6P3EET3
uniprot id: W5Q7K4
names: Caution
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:TRAF1
gene id: 9940:TRAF1
uniprot id: W5P6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9940:TENT5B
gene id: 9940:TENT5B
uniprot id: W5P139
names: Similarity
messages: Belongs to the TENT family.

9940:MASTL
gene id: 9940:MASTL
uniprot id: A0A6P3TJ63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

9940:HYAL2
gene id: 9940:HYAL2
uniprot id: A0A835ZNQ6
uniprot id: Q8SQG7
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a receptor for the Jaagsiekte sheep retrovirus (JSRV), which induces ovine pulmonary adenocarcinoma. A possible mechanism is that binding to JSRV envelope proteins may liberate the oncogenic factor MST1R that is normally negatively regulated by HYAL2, leading to oncogenic transformation.
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product which is further hydrolyzed by sperm hyaluronidase to give small oligosaccharides. Displays very low levels of activity. Associates with and negatively regulates MST1R (By similarity).
messages: Interacts with MST1R (By similarity). Interacts with Jaagsiekte sheep retrovirus (JSRV) envelope proteins.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CD3E
gene id: 9940:CD3E
uniprot id: P29328
uniprot id: Q3S1N5
names: Function
names: PTM
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Membrane
messages: Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways. In addition of this role of signal transduction in T-cell activation, CD3E plays an essential role in correct T-cell development. Initiates the TCR-CD3 complex assembly by forming the two heterodimers CD3D/CD3E and CD3G/CD3E. Participates also in internalization and cell surface down-regulation of TCR-CD3 complexes via endocytosis sequences present in CD3E cytosolic region.
messages: Phosphorylated on Tyr residues after T-cell receptor triggering by LCK in association with CD4/CD8.
messages: The TCR-CD3 complex is composed of a CD3D/CD3E and a CD3G/CD3E heterodimers that preferentially associate with TCRalpha and TCRbeta, respectively, to form TCRalpha/CD3E/CD3G and TCRbeta/CD3G/CD3E trimers. In turn, the hexamer interacts with CD3Z homodimer to form the TCR-CD3 complex. Alternatively, TCRalpha and TCRbeta can be replaced by TCRgamma and TCRdelta. Interacts with CD6. Interacts with NCK1. Interacts with NUMB; this interaction is important for TCR-CD3 internalization and subsequent degradation.

9940:CYGB
gene id: 9940:CYGB
uniprot id: A0A6P3CXP0
uniprot id: C8BKE0
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SSTR3
gene id: 9940:SSTR3
uniprot id: W5QG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9940:SMAP2
gene id: 9940:SMAP2
uniprot id: A0A6P3E662
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF1
gene id: 9940:EIF1
uniprot id: A0A6P3EDI7
names: Similarity
messages: Belongs to the SUI1 family.

9940:IGF2BP1
gene id: 9940:IGF2BP1
uniprot id: A0A6P3YL83
uniprot id: M4R4L7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: filopodium
messages: lamellipodium

9940:GPSM3
gene id: 9940:GPSM3
uniprot id: A0A6P3YP89
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:OSGEPL1
gene id: 9940:OSGEPL1
uniprot id: A0A836AME1
uniprot id: W5Q489
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SLC25A10
gene id: 9940:SLC25A10
uniprot id: B2MVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9940:MAEL
gene id: 9940:MAEL
uniprot id: A0A6P3E7I9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARL14EPL
gene id: 9940:ARL14EPL
uniprot id: A0A6P3TI40
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:EIF1AD
gene id: 9940:EIF1AD
uniprot id: A0A6P3EPQ5
uniprot id: W5NSN1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EIF1AD family.
messages: Interacts with GAPDH and STAT1.
messages: Plays a role into cellular response to oxidative stress. Decreases cell proliferation.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:C3H2orf42
gene id: 9940:C3H2orf42
uniprot id: A0A6P3E279
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MPP7
gene id: 9940:MPP7
uniprot id: W5Q1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: adherens junction
messages: tight junction

9940:APOF
gene id: 9940:APOF
uniprot id: A0A836A872
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CSN1S1
gene id: 9940:CSN1S1
uniprot id: G3LUQ4
uniprot id: P04653
names: Function
names: Polymorphism
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: At least four alleles are known. The sequence shown is that of allele A. The frequency of variant Thr-209 is 0.263, 0.122 and 0.191 in Italian breeds Comisana, Sarda and Sopravissana, respectively.
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Mammary gland specific. Secreted in milk.
messages: Secreted

9940:SCD
gene id: 9940:SCD
uniprot id: O62849
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (By similarity). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation (By similarity). Plays an important role in body energy homeostasis (By similarity). Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides (By similarity).
messages: The histidine box domains are involved in binding the catalytic metal ions.

9940:DVL2
gene id: 9940:DVL2
uniprot id: A0A6P3EIF7
uniprot id: W5PMC0
names: Caution
names: Similarity
messages: Belongs to the DSH family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNTF
gene id: 9940:CNTF
uniprot id: A0A6P3ED95
uniprot id: W5PNJ0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MRPL48
gene id: 9940:MRPL48
uniprot id: A0A6P3ED45
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:PIR
gene id: 9940:PIR
uniprot id: A0A6P3EH18
names: Caution
names: Similarity
messages: Belongs to the pirin family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC105608827
gene id: 9940:LOC105608827
uniprot id: A0A836A6D3
names: Caution
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Binds directly to 26S ribosomal RNA.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LIN9
gene id: 9940:LIN9
uniprot id: A0A6P3EE22
names: Caution
names: Similarity
messages: Belongs to the lin-9 family.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101114385
gene id: 9940:LOC101114385
uniprot id: W5P9F1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9940:F2RL2
gene id: 9940:F2RL2
uniprot id: W5Q630
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:MAP4K1
gene id: 9940:MAP4K1
uniprot id: A0A6P3TZD5
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CYB561
gene id: 9940:CYB561
uniprot id: A0A835ZVR5
uniprot id: Q95204
names: Caution
names: Cofactor
names: Function
names: Subcellular Location Annotation
messages: Binds 2 heme b groups non-covalently.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: Transmembrane reductase that uses ascorbate as an electron donor in the cytoplasm and transfers electrons across membranes to reduce monodehydro-L-ascorbate radical in the lumen of secretory vesicles. It is therefore involved the regeneration and homeostasis within secretory vesicles of ascorbate which in turn provides reducing equivalents needed to support the activity of intravesicular enzymes.
messages: chromaffin granule membrane

9940:BCL2L11
gene id: 9940:BCL2L11
uniprot id: A0A6P3TPJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Bcl-2 family.
messages: Forms heterodimers with a number of antiapoptotic Bcl-2 proteins including MCL1, BCL2, BCL2L1 isoform Bcl-X(L), BCL2A1/BFL-1.
messages: Induces apoptosis and anoikis.

9940:LOC101116849
gene id: 9940:LOC101116849
uniprot id: A0A6P3E945
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:SMC3
gene id: 9940:SMC3
uniprot id: W5PJ45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9940:TSPAN1
gene id: 9940:TSPAN1
uniprot id: A0A6P3DYP9
uniprot id: A0A6P3T8R3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CNTN1
gene id: 9940:CNTN1
uniprot id: W5QF51
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9940:KLHL13
gene id: 9940:KLHL13
uniprot id: A0A6P3YQE1
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ALDOA
gene id: 9940:ALDOA
uniprot id: A0A6P7DGM3
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9940:SACM1L
gene id: 9940:SACM1L
uniprot id: A0A836CUA3
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MMP2
gene id: 9940:MMP2
uniprot id: A0A6P9FQM5
uniprot id: C8BKE4
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Interacts (via the C-terminal hemopexin-like domains-containing region) with the integrin alpha-V/beta-3; the interaction promotes vascular invasion in angiogenic vessels and melamoma cells. Interacts (via the C-terminal PEX domain) with TIMP2 (via the C-terminal); the interaction inhibits the degradation activity. Interacts with GSK3B.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.
messages: extracellular matrix

9940:CCR7
gene id: 9940:CCR7
uniprot id: W5PZG4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9940:KRT2.11
gene id: 9940:KRT2.11
uniprot id: E3VW87
names: Similarity
messages: Belongs to the intermediate filament family.

9940:CIDEA
gene id: 9940:CIDEA
uniprot id: A0A835ZV84
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:MDM4
gene id: 9940:MDM4
uniprot id: A0A6P7ELG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

9940:ZNF75D
gene id: 9940:ZNF75D
uniprot id: A0A835ZHV9
names: Caution
names: Subcellular Location Annotation
messages: Nucleus
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:NR1H4
gene id: 9940:NR1H4
uniprot id: W5PWS7
uniprot id: W5PWT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9940:PON1
gene id: 9940:PON1
uniprot id: W5NY46
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

9940:NAPA
gene id: 9940:NAPA
uniprot id: A0A6P3YML3
uniprot id: W5PNM6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:LOC101104165
gene id: 9940:LOC101104165
uniprot id: A0A6P3E8N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMO family.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9940:LOC101122140
gene id: 9940:LOC101122140
uniprot id: A0A6P3YS28
uniprot id: W5PVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Very large inducible GTPase (VLIG) family.
messages: Nucleus

9940:TSPAN31
gene id: 9940:TSPAN31
uniprot id: A0A6P3EAQ2
uniprot id: W5P5M1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CCDC60
gene id: 9940:CCDC60
uniprot id: A0A836A1Y7
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:ARID2
gene id: 9940:ARID2
uniprot id: A0A6P3E355
names: Caution
messages: The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.

9940:CES2
gene id: 9940:CES2
uniprot id: W5NX87
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.