9915:FOXS1
gene id: 9915:FOXS1
uniprot id: A0A6P5CSE0
names: Subcellular Location Annotation
messages: Nucleus

9915:SUSD4
gene id: 9915:SUSD4
uniprot id: A0A6P5D6C6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TEDDM1
gene id: 9915:TEDDM1
uniprot id: A0A6P5D6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9915:LOC109563540
gene id: 9915:LOC109563540
uniprot id: A0A6P5CAS7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:TCEA2
gene id: 9915:TCEA2
uniprot id: A0A6P5CN90
uniprot id: A0A6P5CPW3
uniprot id: A0A6P5CRR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

9915:UNC13A
gene id: 9915:UNC13A
uniprot id: A0A6P5C0W0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:ANAPC4
gene id: 9915:ANAPC4
uniprot id: A0A6P5BXQ1
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

9915:LOC109569312
gene id: 9915:LOC109569312
uniprot id: A0A6P5CYI2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GTPBP4
gene id: 9915:GTPBP4
uniprot id: A0A6P5CS96
uniprot id: A0A6P5CTJ0
uniprot id: A0A6P5CVQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9915:NR1H2
gene id: 9915:NR1H2
uniprot id: A0A6P5D990
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9915:LOC109564492
gene id: 9915:LOC109564492
uniprot id: A0A6P5CDH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SHROOM4
gene id: 9915:SHROOM4
uniprot id: A0A6P5BLM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9915:MCPH1
gene id: 9915:MCPH1
uniprot id: A0A6P5AQJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.
messages: Interacts with CDC27 and maybe other components of the APC/C complex. Interacts with histone variant H2AX under DNA damage conditions.
messages: centrosome

9915:LOC109555378
gene id: 9915:LOC109555378
uniprot id: A0A6P5BME3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

9915:MRM2
gene id: 9915:MRM2
uniprot id: A0A6P5DXJ4
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

9915:ASPN
gene id: 9915:ASPN
uniprot id: A0A6P5C9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

9915:CDC25A
gene id: 9915:CDC25A
uniprot id: A0A6P5DQI7
uniprot id: A0A6P5DUG8
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9915:C7H19orf25
gene id: 9915:C7H19orf25
uniprot id: A0A6P5C4B2
names: Similarity
messages: Belongs to the UPF0449 family.

9915:LOC109565636
gene id: 9915:LOC109565636
uniprot id: A0A6P5CIC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TLE3
gene id: 9915:TLE3
uniprot id: A0A6P5CDY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9915:ATP5L
gene id: 9915:ATP5L
uniprot id: A0A6P5CZ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

9915:LOC109558934
gene id: 9915:LOC109558934
uniprot id: A0A6P5BSH9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

9915:LOC109563214
gene id: 9915:LOC109563214
uniprot id: A0A6P5C991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Membrane

9915:LOC109577140
gene id: 9915:LOC109577140
uniprot id: A0A6P5DU72
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

9915:LOC109557786
gene id: 9915:LOC109557786
uniprot id: A0A6P5BCZ0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9915:KRT14
gene id: 9915:KRT14
uniprot id: A0A6P5DI55
names: Similarity
messages: Belongs to the intermediate filament family.

9915:LOC109569371
gene id: 9915:LOC109569371
uniprot id: A0A6P5CZL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554068
gene id: 9915:LOC109554068
uniprot id: A0A6P5AZL3
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

9915:LOC109569387
gene id: 9915:LOC109569387
uniprot id: A0A6P5CZN1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HSP90AB1
gene id: 9915:HSP90AB1
uniprot id: F4NAS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

9915:DNAH10
gene id: 9915:DNAH10
uniprot id: A0A6P5D763
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:LOC109569938
gene id: 9915:LOC109569938
uniprot id: A0A6P5D2L1
names: Similarity
messages: Belongs to the globin family.

9915:C9H6orf120
gene id: 9915:C9H6orf120
uniprot id: A0A6P5CC99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes.
messages: Secreted

9915:LOC109571977
gene id: 9915:LOC109571977
uniprot id: A0A6P5DAN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

9915:SLC2A2
gene id: 9915:SLC2A2
uniprot id: A0A6P5BA57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

9915:GPR87
gene id: 9915:GPR87
uniprot id: A0A6P5BG19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109573026
gene id: 9915:LOC109573026
uniprot id: A0A6P5DBY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9915:CENPI
gene id: 9915:CENPI
uniprot id: A0A6P5BMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-I/CTF3 family.
messages: Nucleus
messages: centromere

9915:FGA
gene id: 9915:FGA
uniprot id: A0A6P5D3L3
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9915:CNFN
gene id: 9915:CNFN
uniprot id: A0A6P5D7T2
names: Similarity
messages: Belongs to the cornifelin family.

9915:CES3
gene id: 9915:CES3
uniprot id: A0A6P5DD45
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9915:SCML2
gene id: 9915:SCML2
uniprot id: A0A6P5B514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9915:LYRM9
gene id: 9915:LYRM9
uniprot id: A0A6P5DIW9
names: Similarity
messages: Belongs to the complex I LYR family. LYRM9 subfamily.

9915:NKAPL
gene id: 9915:NKAPL
uniprot id: A0A6P5DRH0
names: Similarity
messages: Belongs to the NKAP family.

9915:DSP
gene id: 9915:DSP
uniprot id: A0A6P5DTN6
uniprot id: A0A6P5DXF1
names: Subcellular Location Annotation
messages: cytoskeleton

9915:LOC109576705
gene id: 9915:LOC109576705
uniprot id: A0A6P5DV80
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ESCO2
gene id: 9915:ESCO2
uniprot id: A0A6P5C750
uniprot id: A0A6P5C765
names: Subcellular Location Annotation
messages: Nucleus

9915:NFU1
gene id: 9915:NFU1
uniprot id: A0A6P5CIY3
uniprot id: A0A6P5CLB4
uniprot id: A0A6P5CM60
names: Similarity
messages: Belongs to the NifU family.

9915:PAPSS1
gene id: 9915:PAPSS1
uniprot id: A0A6P5BX63
uniprot id: A0A6P5BXP2
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9915:USH2A
gene id: 9915:USH2A
uniprot id: A0A6P5D172
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:AGXT
gene id: 9915:AGXT
uniprot id: A0A6P5B9N3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Peroxisome

9915:SIM1
gene id: 9915:SIM1
uniprot id: A0A6P5CB67
names: Subcellular Location Annotation
messages: Nucleus

9915:HSD17B1
gene id: 9915:HSD17B1
uniprot id: A0A6P5DLL8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:CHST9
gene id: 9915:CHST9
uniprot id: A0A6P5DX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:TOMM20L
gene id: 9915:TOMM20L
uniprot id: A0A6P5CCM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9915:CNTNAP5
gene id: 9915:CNTNAP5
uniprot id: A0A6P5DM40
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
messages: Membrane

9915:USP48
gene id: 9915:USP48
uniprot id: A0A6P5DGZ7
uniprot id: A0A6P5DH53
uniprot id: A0A6P5DIG3
uniprot id: A0A6P5DII0
uniprot id: A0A6P5DJH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family.
messages: Nucleus

9915:TM4SF19
gene id: 9915:TM4SF19
uniprot id: A0A6P5BHU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9915:UBE2L6
gene id: 9915:UBE2L6
uniprot id: A0A6P5D1F5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:GNG2
gene id: 9915:GNG2
uniprot id: A0A6P5CFI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:PLBD2
gene id: 9915:PLBD2
uniprot id: A0A6P5D5I0
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9915:NPR3
gene id: 9915:NPR3
uniprot id: A0A6P5DKF4
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109561013
gene id: 9915:LOC109561013
uniprot id: A0A6P5C084
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PPP6R1
gene id: 9915:PPP6R1
uniprot id: A0A6P5D9E1
uniprot id: A0A6P5DB49
names: Similarity
messages: Belongs to the SAPS family.

9915:MRPL35
gene id: 9915:MRPL35
uniprot id: A0A6P5CK41
uniprot id: A0A6P5CLU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL35 family.
messages: Mitochondrion

9915:LOC109563656
gene id: 9915:LOC109563656
uniprot id: A0A6P5CAE1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109568976
gene id: 9915:LOC109568976
uniprot id: A0A6P5CV18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TUSC5
gene id: 9915:TUSC5
uniprot id: A0A6P5DHG4
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9915:ROM1
gene id: 9915:ROM1
uniprot id: A0A6P5AU66
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

9915:LOC109575781
gene id: 9915:LOC109575781
uniprot id: A0A6P5DN96
names: Similarity
messages: Belongs to the serpin family.

9915:GINS4
gene id: 9915:GINS4
uniprot id: A0A6P5AXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Chromosome
messages: Nucleus
messages: Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built.

9915:SEPT5
gene id: 9915:SEPT5
uniprot id: A0A6P5D498
names: Subcellular Location Annotation
messages: cytoskeleton

9915:LDLR
gene id: 9915:LDLR
uniprot id: A0A6P5C2G7
uniprot id: A0A6P5C3I2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SPIRE2
gene id: 9915:SPIRE2
uniprot id: A0A6P5D6C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

9915:KDM5C
gene id: 9915:KDM5C
uniprot id: A0A6P5AX75
uniprot id: A0A6P5AX79
uniprot id: A0A6P5AX83
uniprot id: A0A6P5AX86
uniprot id: A0A6P5B2Z8
uniprot id: A0A6P5B303
uniprot id: A0A6P5B310
uniprot id: A0A6P5B317
uniprot id: A0A6P5BEZ6
uniprot id: A0A6P5BF02
uniprot id: A0A6P5BF06
uniprot id: A0A6P5BF08
uniprot id: A0A6P5BLL8
uniprot id: A0A6P5BLM1
uniprot id: A0A6P5BLM8
uniprot id: A0A6P5BLN1
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

9915:ARF6
gene id: 9915:ARF6
uniprot id: A0A6P5CGY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Cell membrane
messages: Cleavage furrow
messages: Endosome membrane
messages: Midbody ring
messages: Recycling endosome membrane
messages: filopodium membrane
messages: ruffle

9915:ATP6V0B
gene id: 9915:ATP6V0B
uniprot id: A0A6P5B8G9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

9915:TMEM218
gene id: 9915:TMEM218
uniprot id: A0A6P5BKP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM218 family.
messages: May be involved in ciliary biogenesis or function.
messages: Membrane
messages: cilium

9915:LOC109565943
gene id: 9915:LOC109565943
uniprot id: A0A6P5CHN0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:ROR2
gene id: 9915:ROR2
uniprot id: A0A6P5C905
uniprot id: A0A6P5CAL9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SSTR5
gene id: 9915:SSTR5
uniprot id: A0A6P5DX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:MRPL27
gene id: 9915:MRPL27
uniprot id: A0A6P5DEF6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

9915:SIDT1
gene id: 9915:SIDT1
uniprot id: A0A6P5DJN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

9915:LOC109561027
gene id: 9915:LOC109561027
uniprot id: A0A6P5C1A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HTR3A
gene id: 9915:HTR3A
uniprot id: A0A6P5CVR8
uniprot id: A0A6P5CWL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:ADCYAP1R1
gene id: 9915:ADCYAP1R1
uniprot id: A0A6P5BBT1
uniprot id: A0A6P5BK74
uniprot id: A0A6P5BQR8
names: Subcellular Location Annotation
messages: Membrane

9915:CLDN15
gene id: 9915:CLDN15
uniprot id: A0A6P5E049
uniprot id: A0A6P5E333
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:ZDHHC23
gene id: 9915:ZDHHC23
uniprot id: A0A6P5DM98
uniprot id: A0A6P5DPZ1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:TUBB
gene id: 9915:TUBB
uniprot id: A0A6P5DTY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9915:LOC109570180
gene id: 9915:LOC109570180
uniprot id: A0A6P5D2B6
names: Similarity
messages: Belongs to the PRAME family.

9915:EYA2
gene id: 9915:EYA2
uniprot id: A0A6P5CTZ4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

9915:PNMT
gene id: 9915:PNMT
uniprot id: A0A6P5DIC2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9915:CAT
gene id: 9915:CAT
uniprot id: A0A6P5CZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

9915:LOC109568048
gene id: 9915:LOC109568048
uniprot id: A0A6P5CS05
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109570130
gene id: 9915:LOC109570130
uniprot id: A0A6P5D0C1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109571635
gene id: 9915:LOC109571635
uniprot id: A0A6P5D9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

9915:S100Z
gene id: 9915:S100Z
uniprot id: A0A6P5CDN7
names: Similarity
messages: Belongs to the S-100 family.

9915:DNAJC25
gene id: 9915:DNAJC25
uniprot id: A0A6P5CA03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAJC25 family.
messages: Membrane

9915:LOC109555622
gene id: 9915:LOC109555622
uniprot id: A0A6P5BMZ2
names: Subcellular Location Annotation
messages: Nucleus

9915:SLC1A5
gene id: 9915:SLC1A5
uniprot id: A0A6P5DAX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9915:TRMT2A
gene id: 9915:TRMT2A
uniprot id: A0A6P5D6K5
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NUP155
gene id: 9915:NUP155
uniprot id: A0A6P5DJU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.
messages: nuclear pore complex

9915:LOC109558055
gene id: 9915:LOC109558055
uniprot id: A0A6P5B9T4
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9915:RAB3B
gene id: 9915:RAB3B
uniprot id: A0A6P5BP82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9915:TRUB2
gene id: 9915:TRUB2
uniprot id: A0A6P5CLH0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9915:MMP7
gene id: 9915:MMP7
uniprot id: A0A6P5CVL8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Binds 2 calcium ions per subunit.

9915:RASGRP3
gene id: 9915:RASGRP3
uniprot id: A0A6P5CHR1
uniprot id: A0A6P5CJ80
names: Similarity
messages: Belongs to the RASGRP family.

9915:WRN
gene id: 9915:WRN
uniprot id: A0A6P5AQR8
uniprot id: A0A6P5AXE5
uniprot id: A0A6P5B986
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

9915:KAT5
gene id: 9915:KAT5
uniprot id: A0A6P5AVB3
uniprot id: A0A6P5B198
uniprot id: A0A6P5BKH9
uniprot id: A0A6P5BKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9915:FOXR2
gene id: 9915:FOXR2
uniprot id: A0A6P5ATX2
names: Subcellular Location Annotation
messages: Nucleus

9915:FAM69A
gene id: 9915:FAM69A
uniprot id: A0A6P5B6W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

9915:GADD45A
gene id: 9915:GADD45A
uniprot id: A0A6P5BHS1
names: Similarity
messages: Belongs to the GADD45 family.

9915:LOC109569298
gene id: 9915:LOC109569298
uniprot id: A0A6P5CZC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PAEP
gene id: 9915:PAEP
uniprot id: A0A6P5CMD9
uniprot id: A0A6P5CN21
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9915:CHAF1A
gene id: 9915:CHAF1A
uniprot id: A0A6P5C349
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CHAF1A family.
messages: Nucleus

9915:SLC24A5
gene id: 9915:SLC24A5
uniprot id: A0A6P5CGI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9915:ARRB1
gene id: 9915:ARRB1
uniprot id: A0A6P5CXP8
uniprot id: A0A6P5CYG1
uniprot id: A0A6P5CYM1
uniprot id: A0A6P5D069
names: Similarity
messages: Belongs to the arrestin family.

9915:ERCC1
gene id: 9915:ERCC1
uniprot id: A0A6P5DA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

9915:GCK
gene id: 9915:GCK
uniprot id: A0A6P5BQW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9915:LOC109573214
gene id: 9915:LOC109573214
uniprot id: A0A6P5DET2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ATG4B
gene id: 9915:ATG4B
uniprot id: A0A6P5B588
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: autophagosome
messages: cytosol

9915:AP3B1
gene id: 9915:AP3B1
uniprot id: A0A6P5CEE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes large subunit family.
messages: Subunit of non-clathrin- and clathrin-associated adaptor protein complex 3 (AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.
messages: clathrin-coated vesicle membrane

9915:ANKRD13B
gene id: 9915:ANKRD13B
uniprot id: A0A6P5DHY3
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9915:LOC109561026
gene id: 9915:LOC109561026
uniprot id: A0A6P5C096
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TMPRSS5
gene id: 9915:TMPRSS5
uniprot id: A0A6P5CZI5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109560707
gene id: 9915:LOC109560707
uniprot id: A0A6P5BZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

9915:LOC109569374
gene id: 9915:LOC109569374
uniprot id: A0A6P5CX33
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CHMP1B
gene id: 9915:CHMP1B
uniprot id: A0A6P5DVA9
names: Similarity
messages: Belongs to the SNF7 family.

9915:EEF2K
gene id: 9915:EEF2K
uniprot id: A0A6P5E136
uniprot id: A0A6P5E1K6
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. Alpha-type protein kinase family.
messages: Monomer or homodimer.
messages: Undergoes calcium/calmodulin-dependent intramolecular autophosphorylation, and this results in it becoming partially calcium/calmodulin-independent.

9915:LOC109569392
gene id: 9915:LOC109569392
uniprot id: A0A6P5CX83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MAP3K9
gene id: 9915:MAP3K9
uniprot id: A0A6P5CGW8
uniprot id: A0A6P5CIG5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

9915:SLC13A2
gene id: 9915:SLC13A2
uniprot id: A0A6P5DIX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9915:GABBR1
gene id: 9915:GABBR1
uniprot id: A0A6P5DTF5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:INPP5K
gene id: 9915:INPP5K
uniprot id: A0A6P5DJG5
uniprot id: A0A6P5DJY9
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

9915:LOC109569367
gene id: 9915:LOC109569367
uniprot id: A0A6P5CYP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NATD1
gene id: 9915:NATD1
uniprot id: A0A6P5DFT6
names: Similarity
messages: Belongs to the NATD1 family.

9915:TLR6
gene id: 9915:TLR6
uniprot id: A0A6P5BYA4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:NR3C1
gene id: 9915:NR3C1
uniprot id: A0A6P5C551
uniprot id: A0A6P5C580
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

9915:GNG8
gene id: 9915:GNG8
uniprot id: A0A6P5DC06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:SET
gene id: 9915:SET
uniprot id: A0A6P5CNQ2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109572951
gene id: 9915:LOC109572951
uniprot id: A0A6P5DDZ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:AKAP5
gene id: 9915:AKAP5
uniprot id: A0A6P5CI68
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109568092
gene id: 9915:LOC109568092
uniprot id: A0A6P5CVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

9915:LOC109558474
gene id: 9915:LOC109558474
uniprot id: A0A6P5BLZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109555779
gene id: 9915:LOC109555779
uniprot id: A0A6P5BGQ0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:EFNA5
gene id: 9915:EFNA5
uniprot id: A0A6P5C626
uniprot id: A0A6P5C6I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:RBM42
gene id: 9915:RBM42
uniprot id: A0A6P5D8S6
uniprot id: A0A6P5DAH2
uniprot id: A0A6P5DC73
names: Similarity
messages: Belongs to the RRM RBM42 family.

9915:LOC109569445
gene id: 9915:LOC109569445
uniprot id: A0A6P5CXF2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109555818
gene id: 9915:LOC109555818
uniprot id: A0A6P5B0G5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109562645
gene id: 9915:LOC109562645
uniprot id: A0A6P5C6Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:LOC109555701
gene id: 9915:LOC109555701
uniprot id: A0A6P5BGM5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:GJB3
gene id: 9915:GJB3
uniprot id: A0A6P5BPS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:GPX1
gene id: 9915:GPX1
uniprot id: A0A6P5DPT6
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:PTGDS
gene id: 9915:PTGDS
uniprot id: A0A6P5CKS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Membrane
messages: Monomer.
messages: Nucleus membrane
messages: Rough endoplasmic reticulum
messages: perinuclear region

9915:PPP1R21
gene id: 9915:PPP1R21
uniprot id: A0A6P5CJF6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9915:LOC109570220
gene id: 9915:LOC109570220
uniprot id: A0A6P5D2D8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: Component of the RNA polymerase I (Pol I) and RNA polymerase III (Pol III) complexes consisting of at least 13 and 17 subunits, respectively.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common core component of RNA polymerases I and III which synthesize ribosomal RNA precursors and small RNAs, such as 5S rRNA and tRNAs, respectively.

9915:PTAR1
gene id: 9915:PTAR1
uniprot id: A0A6P5C699
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

9915:MRPL51
gene id: 9915:MRPL51
uniprot id: A0A6P5BVN7
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL51 family.

9915:GPR21
gene id: 9915:GPR21
uniprot id: A0A6P5CJS7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:CPLX4
gene id: 9915:CPLX4
uniprot id: A0A6P5DYU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

9915:KIF15
gene id: 9915:KIF15
uniprot id: A0A6P5DP40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: spindle

9915:LHCGR
gene id: 9915:LHCGR
uniprot id: A0A6P5CHS4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

9915:ETFDH
gene id: 9915:ETFDH
uniprot id: A0A6P5D4F9
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

9915:SNRPD2
gene id: 9915:SNRPD2
uniprot id: A0A6P5DBK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome.
messages: cytosol

9915:ETF1
gene id: 9915:ETF1
uniprot id: A0A6P5C4Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

9915:PTGS1
gene id: 9915:PTGS1
uniprot id: A0A6P5CLG2
uniprot id: A0A6P5CN60
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:KCNJ5
gene id: 9915:KCNJ5
uniprot id: A0A6P5ATG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

9915:C2H2orf88
gene id: 9915:C2H2orf88
uniprot id: A0A6P5CH67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

9915:ZFYVE27
gene id: 9915:ZFYVE27
uniprot id: A0A6P5ANV6
uniprot id: A0A6P5AVU1
uniprot id: A0A6P5B7K8
uniprot id: A0A6P5B7L3
uniprot id: A0A6P5BGE2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

9915:FAM98B
gene id: 9915:FAM98B
uniprot id: A0A6P5CFF5
names: Similarity
messages: Belongs to the FAM98 family.

9915:LOC109558789
gene id: 9915:LOC109558789
uniprot id: A0A6P5BEQ4
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:IL17A
gene id: 9915:IL17A
uniprot id: A0A6P5DRZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

9915:RPL3
gene id: 9915:RPL3
uniprot id: A0A6P5BVW3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

9915:MLNR
gene id: 9915:MLNR
uniprot id: A0A6P5CMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:SH3RF1
gene id: 9915:SH3RF1
uniprot id: A0A6P5C6V2
uniprot id: A0A6P5C6X1
uniprot id: A0A6P5C6X7
uniprot id: A0A6P5C7A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

9915:PSMB8
gene id: 9915:PSMB8
uniprot id: A0A6P5DWP5
uniprot id: A0A6P5DX14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9915:ADAM7
gene id: 9915:ADAM7
uniprot id: A0A6P5C6C4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109558658
gene id: 9915:LOC109558658
uniprot id: A0A6P5BEI1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

9915:SRF
gene id: 9915:SRF
uniprot id: A0A6P5DVN3
names: Subcellular Location Annotation
messages: Nucleus

9915:FOXE3
gene id: 9915:FOXE3
uniprot id: A0A6P5BPB5
names: Subcellular Location Annotation
messages: Nucleus

9915:PADI1
gene id: 9915:PADI1
uniprot id: A0A6P5DQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Cytoplasm

9915:LOC109576895
gene id: 9915:LOC109576895
uniprot id: A0A6P5DS55
names: Similarity
messages: Belongs to the histone H3 family.

9915:LOC109558752
gene id: 9915:LOC109558752
uniprot id: A0A6P5BBL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KPNA2
gene id: 9915:KPNA2
uniprot id: A0A6P5DHY5
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9915:LOC109570113
gene id: 9915:LOC109570113
uniprot id: A0A6P5D0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:SLC24A3
gene id: 9915:SLC24A3
uniprot id: A0A6P5CTB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9915:VSX1
gene id: 9915:VSX1
uniprot id: A0A6P5CT16
names: Subcellular Location Annotation
messages: Nucleus

9915:SMO
gene id: 9915:SMO
uniprot id: A0A6P5BCC1
uniprot id: A0A6P5BKL6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SLC27A2
gene id: 9915:SLC27A2
uniprot id: A0A6P5CEU3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:LOC109564307
gene id: 9915:LOC109564307
uniprot id: A0A6P5CD42
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ADHFE1
gene id: 9915:ADHFE1
uniprot id: A0A6P5CU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

9915:MMP25
gene id: 9915:MMP25
uniprot id: A0A6P5E2L4
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:CCNG1
gene id: 9915:CCNG1
uniprot id: A0A6P5C5M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin G subfamily.
messages: May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation.
messages: Nucleus

9915:RPAIN
gene id: 9915:RPAIN
uniprot id: A0A6P5DHD7
uniprot id: A0A6P5DJT9
names: Subcellular Location Annotation
messages: Nucleus

9915:NUP210L
gene id: 9915:NUP210L
uniprot id: A0A6P5BPZ4
names: Similarity
messages: Belongs to the NUP210 family.

9915:ITGB7
gene id: 9915:ITGB7
uniprot id: A0A6P5BCY8
uniprot id: A0A6P5BN18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

9915:LOC109565828
gene id: 9915:LOC109565828
uniprot id: A0A6P5CI50
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9915:DDO
gene id: 9915:DDO
uniprot id: A0A6P5CB96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9915:NFXL1
gene id: 9915:NFXL1
uniprot id: A0A6P5BY54
uniprot id: A0A6P5BY70
uniprot id: A0A6P5BYM3
names: Similarity
messages: Belongs to the NFX1 family.

9915:CCDC130
gene id: 9915:CCDC130
uniprot id: A0A6P5C285
names: Similarity
messages: Belongs to the CWC16 family.

9915:LOC109556335
gene id: 9915:LOC109556335
uniprot id: A0A6P5BP98
uniprot id: A0A6P5BPC4
names: Similarity
messages: Belongs to the amidase family.

9915:ANXA6
gene id: 9915:ANXA6
uniprot id: A0A6P5C5C4
uniprot id: A0A6P5C5E2
uniprot id: A0A6P5C6S3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

9915:RAPSN
gene id: 9915:RAPSN
uniprot id: A0A6P5D011
names: Similarity
messages: Belongs to the RAPsyn family.

9915:LOC109562734
gene id: 9915:LOC109562734
uniprot id: A0A6P5C864
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RAD54L2
gene id: 9915:RAD54L2
uniprot id: A0A6P5DRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9915:LOC109561184
gene id: 9915:LOC109561184
uniprot id: A0A6P5C0W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PHC2
gene id: 9915:PHC2
uniprot id: A0A6P5D7I4
uniprot id: A0A6P5D7K6
uniprot id: A0A6P5D964
uniprot id: A0A6P5DB88
names: Subcellular Location Annotation
messages: Nucleus

9915:TMEM59
gene id: 9915:TMEM59
uniprot id: A0A6P5B346
uniprot id: A0A6P5B7W3
uniprot id: A0A6P5BHY3
uniprot id: A0A6P5BP47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:TMEM8C
gene id: 9915:TMEM8C
uniprot id: A0A6P5CM24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

9915:STAM
gene id: 9915:STAM
uniprot id: A0A6P5CRI2
uniprot id: A0A6P5CV36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes.

9915:YBEY
gene id: 9915:YBEY
uniprot id: A0A6P5C1D0
names: Similarity
messages: Belongs to the endoribonuclease YbeY family.

9915:PIGV
gene id: 9915:PIGV
uniprot id: A0A6P5DCS6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

9915:GNPDA2
gene id: 9915:GNPDA2
uniprot id: A0A6P5BY52
uniprot id: A0A6P5BYZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

9915:CAMK1G
gene id: 9915:CAMK1G
uniprot id: A0A6P5D4Z7
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:CACNA1B
gene id: 9915:CACNA1B
uniprot id: A0A6P5CHI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1B subfamily.
messages: Membrane

9915:NEFM
gene id: 9915:NEFM
uniprot id: A0A6P5C9V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

9915:LOC109557751
gene id: 9915:LOC109557751
uniprot id: A0A6P5BKX4
names: Similarity
messages: Belongs to the TCAF family.

9915:MCHR1
gene id: 9915:MCHR1
uniprot id: A0A6P5BWB1
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

9915:ANGPTL4
gene id: 9915:ANGPTL4
uniprot id: A0A6P5C2V8
names: Subcellular Location Annotation
messages: Secreted

9915:LOC109556685
gene id: 9915:LOC109556685
uniprot id: A0A6P5B5E5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109565608
gene id: 9915:LOC109565608
uniprot id: A0A6P5CI95
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9915:LOC109562328
gene id: 9915:LOC109562328
uniprot id: A0A6P5C761
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KCNV2
gene id: 9915:KCNV2
uniprot id: A0A6P5C694
names: Subcellular Location Annotation
messages: Membrane

9915:CCR5
gene id: 9915:CCR5
uniprot id: A0A6P5DQS8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109559138
gene id: 9915:LOC109559138
uniprot id: A0A6P5BFV6
uniprot id: A0A6P5BNC2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9915:DCST1
gene id: 9915:DCST1
uniprot id: A0A6P5BQ66
uniprot id: A0A6P5BQ98
names: Subcellular Location Annotation
messages: Membrane

9915:CLDN7
gene id: 9915:CLDN7
uniprot id: A0A6P5DET1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:AKR1E2
gene id: 9915:AKR1E2
uniprot id: A0A6P5CRB3
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:LOC109562852
gene id: 9915:LOC109562852
uniprot id: A0A6P5C793
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha/beta interferon family.
messages: Monomer.
messages: Secreted

9915:HOXD3
gene id: 9915:HOXD3
uniprot id: A0A6P5CJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:PGGT1B
gene id: 9915:PGGT1B
uniprot id: A0A6P5CBX6
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

9915:NDUFA8
gene id: 9915:NDUFA8
uniprot id: A0A6P5CM73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

9915:THBS4
gene id: 9915:THBS4
uniprot id: A0A6P5CCW7
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SLC6A4
gene id: 9915:SLC6A4
uniprot id: A0A6P5DHD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

9915:LOC109565641
gene id: 9915:LOC109565641
uniprot id: A0A6P5CGN7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

9915:GDI1
gene id: 9915:GDI1
uniprot id: A0A6P5BM62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

9915:GTPBP1
gene id: 9915:GTPBP1
uniprot id: A0A6P5BVV3
uniprot id: A0A6P5BVV6
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

9915:MMS22L
gene id: 9915:MMS22L
uniprot id: A0A6P5CC16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

9915:SNUPN
gene id: 9915:SNUPN
uniprot id: A0A6P5DNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snurportin family.
messages: Cytoplasm
messages: Functions as an U snRNP-specific nuclear import adapter. Involved in the trimethylguanosine (m3G)-cap-dependent nuclear import of U snRNPs. Binds specifically to the terminal m3G-cap U snRNAs.
messages: Nucleus

9915:LOC109558749
gene id: 9915:LOC109558749
uniprot id: A0A6P5BS68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SPDYA
gene id: 9915:SPDYA
uniprot id: A0A6P5CI82
names: Similarity
messages: Belongs to the Speedy/Ringo family.

9915:LOC109559782
gene id: 9915:LOC109559782
uniprot id: A0A6P5BVN0
uniprot id: A0A6P5BVP7
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

9915:MAML2
gene id: 9915:MAML2
uniprot id: A0A6P5CZH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9915:FLVCR1
gene id: 9915:FLVCR1
uniprot id: A0A6P5D310
uniprot id: A0A6P5D484
names: Subcellular Location Annotation
messages: Membrane

9915:B4GALT7
gene id: 9915:B4GALT7
uniprot id: A0A6P5C413
uniprot id: A0A6P5C4A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9915:LOC109561072
gene id: 9915:LOC109561072
uniprot id: A0A6P5C1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109576689
gene id: 9915:LOC109576689
uniprot id: A0A6P5DUZ2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CSRNP1
gene id: 9915:CSRNP1
uniprot id: A0A6P5DN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9915:CPB2
gene id: 9915:CPB2
uniprot id: A0A6P5CKZ8
uniprot id: A0A6P5CPM6
names: Similarity
messages: Belongs to the peptidase M14 family.

9915:SLC6A15
gene id: 9915:SLC6A15
uniprot id: A0A6P5BMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

9915:AIM1L
gene id: 9915:AIM1L
uniprot id: A0A6P5DD78
uniprot id: A0A6P5DD92
uniprot id: A0A6P5DFL1
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9915:PRDM12
gene id: 9915:PRDM12
uniprot id: A0A6P5CK88
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

9915:SHOX2
gene id: 9915:SHOX2
uniprot id: A0A6P5BSG6
names: Subcellular Location Annotation
messages: Nucleus

9915:SCTR
gene id: 9915:SCTR
uniprot id: A0A6P5DL81
names: Subcellular Location Annotation
messages: Membrane

9915:GUCA2B
gene id: 9915:GUCA2B
uniprot id: A0A6P5BAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylin family.
messages: Secreted

9915:LOC109575639
gene id: 9915:LOC109575639
uniprot id: A0A6P5DQN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

9915:BAG6
gene id: 9915:BAG6
uniprot id: A0A6P5DRJ2
uniprot id: A0A6P5DRJ7
uniprot id: A0A6P5DT02
uniprot id: A0A6P5DVD3
uniprot id: A0A6P5DVD8
uniprot id: A0A6P5DVH3
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Released extracellularly via exosomes, it is a ligand of the natural killer/NK cells receptor NCR3 and stimulates NK cells cytotoxicity. It may thereby trigger NK cells cytotoxicity against neighboring tumor cells and immature myeloid dendritic cells (DC).
messages: extracellular exosome

9915:ELF5
gene id: 9915:ELF5
uniprot id: A0A6P5CZH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:CENPM
gene id: 9915:CENPM
uniprot id: A0A6P5BW29
names: Subcellular Location Annotation
messages: Nucleus

9915:PROX1
gene id: 9915:PROX1
uniprot id: A0A6P5D242
uniprot id: A0A6P5D4S3
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109565223
gene id: 9915:LOC109565223
uniprot id: A0A6P5CFU5
names: Subcellular Location Annotation
messages: Nucleus

9915:HCRTR1
gene id: 9915:HCRTR1
uniprot id: A0A6P5D9I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109564428
gene id: 9915:LOC109564428
uniprot id: A0A6P5CCC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

9915:MDH1B
gene id: 9915:MDH1B
uniprot id: A0A6P5CZJ6
uniprot id: A0A6P5D216
uniprot id: A0A6P5D370
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

9915:ST8SIA1
gene id: 9915:ST8SIA1
uniprot id: A0A6P5BV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:ISCA2
gene id: 9915:ISCA2
uniprot id: A0A6P5CFU8
uniprot id: A0A6P5CHH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

9915:ARHGAP32
gene id: 9915:ARHGAP32
uniprot id: A0A6P5B194
uniprot id: A0A6P5BKH8
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

9915:LOC109561173
gene id: 9915:LOC109561173
uniprot id: A0A6P5C0L1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569380
gene id: 9915:LOC109569380
uniprot id: A0A6P5CZM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109564740
gene id: 9915:LOC109564740
uniprot id: A0A6P5CED0
names: Similarity
messages: Belongs to the ARTD/PARP family.

9915:INCENP
gene id: 9915:INCENP
uniprot id: A0A6P5AVM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Midbody
messages: Nucleus
messages: kinetochore
messages: spindle

9915:RPS6KA4
gene id: 9915:RPS6KA4
uniprot id: A0A6P5BKP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
messages: Cytoplasm

9915:LOC109569142
gene id: 9915:LOC109569142
uniprot id: A0A6P5CYT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CHRDL2
gene id: 9915:CHRDL2
uniprot id: A0A6P5D2E6
names: Subcellular Location Annotation
messages: Secreted

9915:DEGS2
gene id: 9915:DEGS2
uniprot id: A0A6P5DL95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:YWHAE
gene id: 9915:YWHAE
uniprot id: A0A6P5DGG5
uniprot id: A0A6P5DH76
names: Similarity
messages: Belongs to the 14-3-3 family.

9915:TFDP1
gene id: 9915:TFDP1
uniprot id: A0A6P5CMN3
uniprot id: A0A6P5CNU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:WISP1
gene id: 9915:WISP1
uniprot id: A0A6P5CWX5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:AFF2
gene id: 9915:AFF2
uniprot id: A0A6P5BE83
names: Similarity
messages: Belongs to the AF4 family.

9915:LOC109566484
gene id: 9915:LOC109566484
uniprot id: A0A6P5CLR8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9915:CLDN2
gene id: 9915:CLDN2
uniprot id: A0A6P5BMR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:LOC109568936
gene id: 9915:LOC109568936
uniprot id: A0A6P5CXH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554178
gene id: 9915:LOC109554178
uniprot id: A0A6P5AZV0
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:DES
gene id: 9915:DES
uniprot id: A0A6P5D7M1
names: Similarity
messages: Belongs to the intermediate filament family.

9915:NXT1
gene id: 9915:NXT1
uniprot id: A0A6P5CS08
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9915:GABARAPL2
gene id: 9915:GABARAPL2
uniprot id: A0A6P5D7M9
names: Similarity
messages: Belongs to the ATG8 family.

9915:TAS2R16
gene id: 9915:TAS2R16
uniprot id: A0A6P5BRP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:LOC109571681
gene id: 9915:LOC109571681
uniprot id: A0A6P5D8L8
names: Similarity
messages: Belongs to the PDCD5 family.

9915:FAM26F
gene id: 9915:FAM26F
uniprot id: A0A6P5CAL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9915:GPNMB
gene id: 9915:GPNMB
uniprot id: A0A6P5BB26
names: Similarity
messages: Belongs to the PMEL/NMB family.

9915:KIF13A
gene id: 9915:KIF13A
uniprot id: A0A6P5DV31
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109554252
gene id: 9915:LOC109554252
uniprot id: A0A6P5B007
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NFIX
gene id: 9915:NFIX
uniprot id: A0A6P5C1U7
uniprot id: A0A6P5C280
uniprot id: A0A6P5C2A2
uniprot id: A0A6P5C321
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

9915:LOC109574552
gene id: 9915:LOC109574552
uniprot id: A0A6P5DLM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9915:ITGA3
gene id: 9915:ITGA3
uniprot id: A0A6P5DJW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:NXT2
gene id: 9915:NXT2
uniprot id: A0A6P5AZ53
uniprot id: A0A6P5BGB0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9915:LOC109575751
gene id: 9915:LOC109575751
uniprot id: A0A6P5DN73
uniprot id: A0A6P5DRE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

9915:CDCA7
gene id: 9915:CDCA7
uniprot id: A0A6P5CJM5
uniprot id: A0A6P5CLD1
uniprot id: A0A6P5CLD8
uniprot id: A0A6P5CM36
uniprot id: A0A6P5CN43
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:PIK3C2G
gene id: 9915:PIK3C2G
uniprot id: A0A6P5BUX7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9915:CLPP
gene id: 9915:CLPP
uniprot id: A0A6P5C2R4
names: Similarity
messages: Belongs to the peptidase S14 family.

9915:CHRNA1
gene id: 9915:CHRNA1
uniprot id: A0A6P5CKV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:TINAGL1
gene id: 9915:TINAGL1
uniprot id: A0A6P5D9L8
names: Similarity
messages: Belongs to the peptidase C1 family.

9915:FN3K
gene id: 9915:FN3K
uniprot id: A0A6P5DJT7
names: Similarity
messages: Belongs to the fructosamine kinase family.

9915:TAGLN
gene id: 9915:TAGLN
uniprot id: A0A6P5CZI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calponin family.
messages: Cytoplasm

9915:HTR1F
gene id: 9915:HTR1F
uniprot id: A0A6P5CCQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
messages: Membrane

9915:UFC1
gene id: 9915:UFC1
uniprot id: A0A6P5DXW8
uniprot id: A0A6P5E1E2
names: Function
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UFC1 subfamily.
messages: E1-like enzyme which specifically catalyzes the second step in ufmylation. Ufmylation is involved in reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

9915:SPTAN1
gene id: 9915:SPTAN1
uniprot id: A0A6P5CKA0
uniprot id: A0A6P5CLJ4
uniprot id: A0A6P5CLK0
uniprot id: A0A6P5CM00
uniprot id: A0A6P5CMN7
uniprot id: A0A6P5CMP6
uniprot id: A0A6P5CNP1
uniprot id: A0A6P5CNP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spectrin family.
messages: cell cortex
messages: cytoskeleton

9915:KIF1B
gene id: 9915:KIF1B
uniprot id: A0A6P5CZX3
uniprot id: A0A6P5CZX8
uniprot id: A0A6P5D0K9
uniprot id: A0A6P5D0L6
uniprot id: A0A6P5D102
uniprot id: A0A6P5D107
uniprot id: A0A6P5D112
uniprot id: A0A6P5D2G5
uniprot id: A0A6P5D2H0
uniprot id: A0A6P5D2H6
uniprot id: A0A6P5D3M3
uniprot id: A0A6P5D3M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: axon

9915:PAIP2B
gene id: 9915:PAIP2B
uniprot id: A0A6P5CIN6
names: Similarity
messages: Belongs to the PAIP2 family.

9915:GRIK5
gene id: 9915:GRIK5
uniprot id: A0A6P5DBT8
uniprot id: A0A6P5DDS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:LOC109576835
gene id: 9915:LOC109576835
uniprot id: A0A6P5DT22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ALOX5AP
gene id: 9915:ALOX5AP
uniprot id: A0A6P5CNF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:UNC5C
gene id: 9915:UNC5C
uniprot id: A0A6P5BWZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9915:CENPN
gene id: 9915:CENPN
uniprot id: A0A6P5DD53
names: Similarity
messages: Belongs to the CENP-N/CHL4 family.

9915:TPRA1
gene id: 9915:TPRA1
uniprot id: A0A6P5B5C6
uniprot id: A0A6P5BJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

9915:PROX2
gene id: 9915:PROX2
uniprot id: A0A6P5CFV7
names: Subcellular Location Annotation
messages: Nucleus

9915:CDKN3
gene id: 9915:CDKN3
uniprot id: A0A6P5CF45
uniprot id: A0A6P5CFN4
uniprot id: A0A6P5CGC4
uniprot id: A0A6P5CGN5
uniprot id: A0A6P5CGN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

9915:TRIM45
gene id: 9915:TRIM45
uniprot id: A0A6P5B0T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9915:CENPJ
gene id: 9915:CENPJ
uniprot id: A0A6P5CN47
names: Similarity
messages: Belongs to the TCP10 family.

9915:CCL21
gene id: 9915:CCL21
uniprot id: A0A6P5C955
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:FGD5
gene id: 9915:FGD5
uniprot id: A0A6P5DQ17
uniprot id: A0A6P5DT87
uniprot id: A0A6P5DTJ2
names: Subcellular Location Annotation
messages: cytoskeleton

9915:GPRIN2
gene id: 9915:GPRIN2
uniprot id: A0A6P5ARY2
names: Function
messages: May be involved in neurite outgrowth.

9915:GPC6
gene id: 9915:GPC6
uniprot id: A0A6P5CNC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

9915:DNAJC2
gene id: 9915:DNAJC2
uniprot id: A0A6P5BBA6
names: Function
names: Subcellular Location Annotation
messages: Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
messages: cytosol

9915:CMBL
gene id: 9915:CMBL
uniprot id: A0A6P5DJX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

9915:GPR1
gene id: 9915:GPR1
uniprot id: A0A6P5D021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

9915:SEC31A
gene id: 9915:SEC31A
uniprot id: A0A6P5BX28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

9915:GNGT2
gene id: 9915:GNGT2
uniprot id: A0A6P5DJ12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:LOC109568943
gene id: 9915:LOC109568943
uniprot id: A0A6P5CVW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MSANTD3
gene id: 9915:MSANTD3
uniprot id: A0A6P5C9S2
names: Similarity
messages: Belongs to the MSANTD3 family.

9915:NIPA2
gene id: 9915:NIPA2
uniprot id: A0A6P5CEC5
uniprot id: A0A6P5CFG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9915:LOC109555648
gene id: 9915:LOC109555648
uniprot id: A0A6P5BMX6
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109571667
gene id: 9915:LOC109571667
uniprot id: A0A6P5D6E2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9915:MSRB1
gene id: 9915:MSRB1
uniprot id: A0A6P5DYQ0
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.

9915:CTBP1
gene id: 9915:CTBP1
uniprot id: A0A6P5C0F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

9915:LOC109564303
gene id: 9915:LOC109564303
uniprot id: A0A6P5CDF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CLSTN3
gene id: 9915:CLSTN3
uniprot id: A0A6P5BSC6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

9915:PUS10
gene id: 9915:PUS10
uniprot id: A0A6P5CJA8
uniprot id: A0A6P5CKK7
names: Similarity
messages: Belongs to the pseudouridine synthase Pus10 family.

9915:SEPHS1
gene id: 9915:SEPHS1
uniprot id: A0A6P5CTT6
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9915:CDC42EP1
gene id: 9915:CDC42EP1
uniprot id: A0A6P5BW05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9915:GPR156
gene id: 9915:GPR156
uniprot id: A0A6P5DYC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

9915:FECH
gene id: 9915:FECH
uniprot id: A0A6P5DZ75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

9915:LTBP4
gene id: 9915:LTBP4
uniprot id: A0A6P5D6B1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:LOC109554260
gene id: 9915:LOC109554260
uniprot id: A0A6P5BC01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:C29H11orf68
gene id: 9915:C29H11orf68
uniprot id: A0A6P5AVD6
names: Similarity
messages: Belongs to the UPF0696 family.

9915:TBCCD1
gene id: 9915:TBCCD1
uniprot id: A0A6P5B6B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBCC family.
messages: centrosome
messages: spindle pole

9915:TMCO3
gene id: 9915:TMCO3
uniprot id: A0A6P5CNU1
uniprot id: A0A6P5CR67
names: Subcellular Location Annotation
messages: Membrane

9915:AK2
gene id: 9915:AK2
uniprot id: A0A6P5D7R8
uniprot id: A0A6P5DBD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

9915:CD28
gene id: 9915:CD28
uniprot id: A0A6P5D147
names: Subcellular Location Annotation
messages: Membrane

9915:C17H12orf43
gene id: 9915:C17H12orf43
uniprot id: A0A6P5D540
uniprot id: A0A6P5D8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUSTOS family.
messages: Nucleus envelope

9915:TRIAP1
gene id: 9915:TRIAP1
uniprot id: A0A6P5D5L9
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

9915:DNAH6
gene id: 9915:DNAH6
uniprot id: A0A6P5CHT7
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:RXFP1
gene id: 9915:RXFP1
uniprot id: A0A6P5D534
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:PARG
gene id: 9915:PARG
uniprot id: A0A6P5ARB3
uniprot id: A0A6P5BHY1
names: Similarity
messages: Belongs to the poly(ADP-ribose) glycohydrolase family.

9915:GBA2
gene id: 9915:GBA2
uniprot id: A0A6P5C8B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

9915:LOC109561581
gene id: 9915:LOC109561581
uniprot id: A0A6P5C3C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9915:CELF3
gene id: 9915:CELF3
uniprot id: A0A6P5BAM3
uniprot id: A0A6P5BQ75
uniprot id: A0A6P5BQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9915:LOC109556955
gene id: 9915:LOC109556955
uniprot id: A0A6P5BJG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

9915:LOC109557600
gene id: 9915:LOC109557600
uniprot id: A0A6P5BKK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

9915:GOLPH3
gene id: 9915:GOLPH3
uniprot id: A0A6P5DMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9915:TLR3
gene id: 9915:TLR3
uniprot id: A0A6P5AWX5
uniprot id: A0A6P5B8S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9915:DNTTIP1
gene id: 9915:DNTTIP1
uniprot id: A0A6P5CQR7
uniprot id: A0A6P5CR80
uniprot id: A0A6P5CS17
uniprot id: A0A6P5CT71
names: Subcellular Location Annotation
messages: Nucleus

9915:OTOGL
gene id: 9915:OTOGL
uniprot id: A0A6P5BAK1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ST7
gene id: 9915:ST7
uniprot id: A0A6P5B748
uniprot id: A0A6P5B752
uniprot id: A0A6P5BBJ5
uniprot id: A0A6P5BBK0
uniprot id: A0A6P5BK22
uniprot id: A0A6P5BK25
uniprot id: A0A6P5BQM9
uniprot id: A0A6P5BQN1
uniprot id: A0A6P5BQN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9915:LOC109562981
gene id: 9915:LOC109562981
uniprot id: A0A6P5C939
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.

9915:LOC109573891
gene id: 9915:LOC109573891
uniprot id: A0A6P5DH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:YAE1D1
gene id: 9915:YAE1D1
uniprot id: A0A6P5BC70
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:ATXN10
gene id: 9915:ATXN10
uniprot id: A0A6P5BWS0
names: Function
names: Similarity
messages: Belongs to the ataxin-10 family.
messages: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis.

9915:NDUFV1
gene id: 9915:NDUFV1
uniprot id: A0A6P5BKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 51 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane

9915:LOC109572183
gene id: 9915:LOC109572183
uniprot id: A0A6P5D7Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109569181
gene id: 9915:LOC109569181
uniprot id: A0A6P5CWD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CADM2
gene id: 9915:CADM2
uniprot id: A0A6P5C5F0
names: Similarity
messages: Belongs to the nectin family.

9915:C15H11orf49
gene id: 9915:C15H11orf49
uniprot id: A0A6P5CXH3
uniprot id: A0A6P5CZX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSTPP1 family.
messages: centriolar satellite

9915:LOC109576834
gene id: 9915:LOC109576834
uniprot id: A0A6P5DRL2
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109564322
gene id: 9915:LOC109564322
uniprot id: A0A6P5CE56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:ISCU
gene id: 9915:ISCU
uniprot id: A0A6P5D5J0
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

9915:FOXR1
gene id: 9915:FOXR1
uniprot id: A0A6P5CWA2
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109553121
gene id: 9915:LOC109553121
uniprot id: A0A6P5AP76
names: Caution
names: Similarity
messages: Belongs to the spermadhesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:HOXB7
gene id: 9915:HOXB7
uniprot id: A0A6P5DI98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:LOC109572275
gene id: 9915:LOC109572275
uniprot id: A0A6P5DAN9
names: Subcellular Location Annotation
messages: Nucleus

9915:GPM6B
gene id: 9915:GPM6B
uniprot id: A0A6P5AXP3
uniprot id: A0A6P5B3L6
uniprot id: A0A6P5BFF9
uniprot id: A0A6P5BLX6
uniprot id: A0A6P5BLZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9915:SH3BGRL2
gene id: 9915:SH3BGRL2
uniprot id: A0A6P5CAD8
names: Similarity
messages: Belongs to the SH3BGR family.

9915:LOC109568177
gene id: 9915:LOC109568177
uniprot id: A0A6P5CTE3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:SFRP1
gene id: 9915:SFRP1
uniprot id: A0A6P5BHJ6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:ADCY1
gene id: 9915:ADCY1
uniprot id: A0A6P5BQU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9915:LOC109556510
gene id: 9915:LOC109556510
uniprot id: A0A6P5B960
uniprot id: A0A6P5BIR6
uniprot id: A0A6P5BPM1
uniprot id: A0A6P5BPQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family.
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5 and TNRC6B. Interacts with APOBEC3F, APOBEC3G and APOBEC3H.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9915:PRKAR1A
gene id: 9915:PRKAR1A
uniprot id: A0A6P5DES3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9915:HHATL
gene id: 9915:HHATL
uniprot id: A0A6P5DP19
names: Subcellular Location Annotation
messages: Membrane

9915:PKLR
gene id: 9915:PKLR
uniprot id: A0A6P5B9I1
uniprot id: A0A6P5BI32
names: Similarity
messages: Belongs to the pyruvate kinase family.

9915:RAN
gene id: 9915:RAN
uniprot id: A0A6P5D5L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

9915:LOC109563235
gene id: 9915:LOC109563235
uniprot id: A0A6P5C963
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:HAT1
gene id: 9915:HAT1
uniprot id: A0A6P5CK50
uniprot id: A0A6P5CNI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

9915:DYNLT3
gene id: 9915:DYNLT3
uniprot id: A0A6P5DK35
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:VAMP7
gene id: 9915:VAMP7
uniprot id: A0A6P5BFQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9915:GCN1
gene id: 9915:GCN1
uniprot id: A0A6P5D7T7
names: Similarity
messages: Belongs to the GCN1 family.

9915:CCNG2
gene id: 9915:CCNG2
uniprot id: A0A6P5BYY6
names: Similarity
messages: Belongs to the cyclin family.

9915:LOC109568641
gene id: 9915:LOC109568641
uniprot id: A0A6P5CWP8
names: Similarity
messages: Belongs to the peptidase C48 family.

9915:RRP1B
gene id: 9915:RRP1B
uniprot id: A0A6P5C0L0
names: Similarity
messages: Belongs to the RRP1 family.

9915:LOC109558374
gene id: 9915:LOC109558374
uniprot id: A0A6P5BRX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ADAMTS2
gene id: 9915:ADAMTS2
uniprot id: A0A6P5C1B3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:LOC109560232
gene id: 9915:LOC109560232
uniprot id: A0A6P5B2C4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9915:LOC109561249
gene id: 9915:LOC109561249
uniprot id: A0A6P5C1T4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DSCC1
gene id: 9915:DSCC1
uniprot id: A0A6P5CVK1
names: Similarity
messages: Belongs to the DCC1 family.

9915:NKX2-1
gene id: 9915:NKX2-1
uniprot id: A0A6P5DM22
names: Subcellular Location Annotation
messages: Nucleus

9915:SUPT6H
gene id: 9915:SUPT6H
uniprot id: A0A6P5DI38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

9915:LSR
gene id: 9915:LSR
uniprot id: A0A6P5D8N3
uniprot id: A0A6P5DAA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

9915:ASNA1
gene id: 9915:ASNA1
uniprot id: A0A6P5C343
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the membrane-bound receptor, and returning it to the cytosol to initiate a new round of targeting.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Homodimer. Component of a transmembrane domain recognition complex (TRC). Interacts with SERP1 and SEC61B. Interacts with WRB.
messages: nucleolus

9915:LIG4
gene id: 9915:LIG4
uniprot id: A0A6P5CMB9
uniprot id: A0A6P5CPT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9915:DPF1
gene id: 9915:DPF1
uniprot id: A0A6P5DC49
uniprot id: A0A6P5DF96
names: Similarity
messages: Belongs to the requiem/DPF family.

9915:DSCR3
gene id: 9915:DSCR3
uniprot id: A0A6P5C2J9
names: Similarity
messages: Belongs to the VPS26 family.

9915:NDUFA2
gene id: 9915:NDUFA2
uniprot id: A0A6P5C573
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:PRDX5
gene id: 9915:PRDX5
uniprot id: A0A6P5B0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Peroxisome matrix
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.

9915:DNAJA2
gene id: 9915:DNAJA2
uniprot id: A0A6P5DA00
names: Subcellular Location Annotation
messages: Membrane

9915:ORAI2
gene id: 9915:ORAI2
uniprot id: A0A6P5DZP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9915:NANOG
gene id: 9915:NANOG
uniprot id: A0A6P5BET2
uniprot id: A0A6P5BSB4
names: Subcellular Location Annotation
messages: Nucleus

9915:CREG2
gene id: 9915:CREG2
uniprot id: A0A6P5CHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

9915:LOC109558780
gene id: 9915:LOC109558780
uniprot id: A0A6P5BEQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109561220
gene id: 9915:LOC109561220
uniprot id: A0A6P5C0Q0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109564497
gene id: 9915:LOC109564497
uniprot id: A0A6P5CEL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SPESP1
gene id: 9915:SPESP1
uniprot id: A0A6P5CBY9
names: Function
names: Similarity
messages: Belongs to the SPESP1 family.
messages: Involved in fertilization ability of sperm.

9915:KITLG
gene id: 9915:KITLG
uniprot id: A0A6P5BLT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: filopodium
messages: lamellipodium

9915:PRKCE
gene id: 9915:PRKCE
uniprot id: A0A6P5CL83
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin-dependent signaling, by mediating angiotensin-2-induced activation of integrin beta-1 (ITGB1) in cardiac fibroblasts. Phosphorylates MARCKS, which phosphorylates and activates PTK2/FAK, leading to the spread of cardiomyocytes. Involved in the control of the directional transport of ITGB1 in mesenchymal cells by phosphorylating vimentin (VIM), an intermediate filament (IF) protein. In epithelial cells, associates with and phosphorylates keratin-8 (KRT8), which induces targeting of desmoplakin at desmosomes and regulates cell-cell contact. Phosphorylates IQGAP1, which binds to CDC42, mediating epithelial cell-cell detachment prior to migration.
messages: Cell membrane
messages: Cytoplasm
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: cytoskeleton
messages: perinuclear region

9915:ENPP4
gene id: 9915:ENPP4
uniprot id: A0A6P5DTE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Cell membrane
messages: Hydrolyzes extracellular Ap3A into AMP and ADP, and Ap4A into AMP and ATP. Ap3A and Ap4A are diadenosine polyphosphates thought to induce proliferation of vascular smooth muscle cells. Acts as a procoagulant, mediating platelet aggregation at the site of nascent thrombus via release of ADP from Ap3A and activation of ADP receptors.
messages: Membrane

9915:PGM3
gene id: 9915:PGM3
uniprot id: A0A6P5CC09
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O-glycosylation.

9915:LOC109560838
gene id: 9915:LOC109560838
uniprot id: A0A6P5BZY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DSTN
gene id: 9915:DSTN
uniprot id: A0A6P5CSW4
names: Function
names: Similarity
messages: Actin-depolymerizing protein. Severs actin filaments (F-actin) and binds to actin monomers (G-actin). Acts in a pH-independent manner.
messages: Belongs to the actin-binding proteins ADF family.

9915:METTL26
gene id: 9915:METTL26
uniprot id: A0A6P5DX89
uniprot id: A0A6P5DXF0
uniprot id: A0A6P5E0X4
uniprot id: A0A6P5E1E3
names: Similarity
messages: Belongs to the UPF0585 family.

9915:LOC109575697
gene id: 9915:LOC109575697
uniprot id: A0A6P5DQX3
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109560113
gene id: 9915:LOC109560113
uniprot id: A0A6P5BWK3
uniprot id: A0A6P5BWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9915:CBR3
gene id: 9915:CBR3
uniprot id: A0A6P5C1M8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9915:FGG
gene id: 9915:FGG
uniprot id: A0A6P5D4T4
uniprot id: A0A6P5D5Z7
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9915:IPO8
gene id: 9915:IPO8
uniprot id: A0A6P5BUM9
names: Subcellular Location Annotation
messages: Cytoplasm

9915:MAB21L3
gene id: 9915:MAB21L3
uniprot id: A0A6P5BNB3
names: Similarity
messages: Belongs to the mab-21 family.

9915:PAQR4
gene id: 9915:PAQR4
uniprot id: A0A6P5DZL4
uniprot id: A0A6P5E392
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9915:ZC3H14
gene id: 9915:ZC3H14
uniprot id: A0A6P5CG85
uniprot id: A0A6P5CHH3
uniprot id: A0A6P5CHW2
uniprot id: A0A6P5CJ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

9915:FZD8
gene id: 9915:FZD8
uniprot id: A0A6P5CTM7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SOSTDC1
gene id: 9915:SOSTDC1
uniprot id: A0A6P5BQF0
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:EIF4A1
gene id: 9915:EIF4A1
uniprot id: A0A6P5DFL9
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

9915:GNPNAT1
gene id: 9915:GNPNAT1
uniprot id: A0A6P5CCX1
uniprot id: A0A6P5CEG3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family. GNA1 subfamily.
messages: Homodimer.

9915:ACVR1C
gene id: 9915:ACVR1C
uniprot id: A0A6P5CPN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9915:TUB
gene id: 9915:TUB
uniprot id: A0A6P5CY49
uniprot id: A0A6P5CZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

9915:CD40
gene id: 9915:CD40
uniprot id: A0A6P5CPR6
uniprot id: A0A6P5CS33
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:PDE9A
gene id: 9915:PDE9A
uniprot id: A0A6P5BZ70
uniprot id: A0A6P5BZ83
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:NRF1
gene id: 9915:NRF1
uniprot id: A0A6P5B885
uniprot id: A0A6P5BCC7
uniprot id: A0A6P5BKM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

9915:OAZ2
gene id: 9915:OAZ2
uniprot id: A0A6P5CET3
names: Similarity
messages: Belongs to the ODC antizyme family.

9915:TPR
gene id: 9915:TPR
uniprot id: A0A6P5D1L8
names: Similarity
messages: Belongs to the TPR family.

9915:NLGN2
gene id: 9915:NLGN2
uniprot id: A0A6P5DEC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

9915:GUCY2D
gene id: 9915:GUCY2D
uniprot id: A0A6P5DLU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9915:TIMM50
gene id: 9915:TIMM50
uniprot id: A0A6P5DDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9915:RBPJ
gene id: 9915:RBPJ
uniprot id: A0A6P5BXR0
uniprot id: A0A6P5BXR3
uniprot id: A0A6P5BXS5
uniprot id: A0A6P5BY81
uniprot id: A0A6P5BYK1
uniprot id: A0A6P5BYK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

9915:POMGNT1
gene id: 9915:POMGNT1
uniprot id: A0A6P5BI83
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 13 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Participates in O-mannosyl glycosylation by catalyzing the addition of N-acetylglucosamine to O-linked mannose on glycoproteins. Catalyzes the synthesis of the GlcNAc(beta1-2)Man(alpha1-)O-Ser/Thr moiety on alpha-dystroglycan and other O-mannosylated proteins, providing the necessary basis for the addition of further carbohydrate moieties. Is specific for alpha linked terminal mannose.
messages: The manganese ion interacts primarily with the substrate UDP-N-acetylglucosamine.
messages: The stem domain mediates specific interaction with beta-linked N-acetylglucosamine moieties of O-glycosylated proteins. It also interacts with its product, N-acetyl-beta-D-glucosaminyl-(1->2)-O-alpha-D-mannosylprotein.

9915:PLSCR5
gene id: 9915:PLSCR5
uniprot id: A0A6P5C8L8
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9915:LOC109563934
gene id: 9915:LOC109563934
uniprot id: A0A6P5CCZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MCMBP
gene id: 9915:MCMBP
uniprot id: A0A6P5E0Z8
uniprot id: A0A6P5E1N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCMBP family.
messages: Nucleus

9915:ARGLU1
gene id: 9915:ARGLU1
uniprot id: A0A6P5CP32
names: Similarity
messages: Belongs to the UPF0430 family.

9915:FLAD1
gene id: 9915:FLAD1
uniprot id: A0A6P5AZ03
uniprot id: A0A6P5BIZ0
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

9915:TM6SF2
gene id: 9915:TM6SF2
uniprot id: A0A6P5C166
uniprot id: A0A6P5C1I6
names: Subcellular Location Annotation
messages: Membrane

9915:CDC42
gene id: 9915:CDC42
uniprot id: A0A6P5DJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.
messages: centrosome

9915:NKX2-3
gene id: 9915:NKX2-3
uniprot id: A0A6P5E4A8
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109579059
gene id: 9915:LOC109579059
uniprot id: A0A6P5E0I9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with chaperones HSP70 and HSP90; this interaction is required for initial targeting to mitochondria.
messages: Microsome membrane
messages: Mitochondrion inner membrane
messages: The omega-1 hydroxylase activity is stimulated by cytochrome b5.

9915:CES2
gene id: 9915:CES2
uniprot id: A0A6P5D9Q1
uniprot id: A0A6P5D9V0
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9915:LTN1
gene id: 9915:LTN1
uniprot id: A0A6P5BRA4
uniprot id: A0A6P5BRA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

9915:SEC24D
gene id: 9915:SEC24D
uniprot id: A0A6P5BWZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9915:NUS1
gene id: 9915:NUS1
uniprot id: A0A6P5CA58
names: Similarity
messages: Belongs to the UPP synthase family.

9915:LOC109569583
gene id: 9915:LOC109569583
uniprot id: A0A6P5CZU3
names: Subcellular Location Annotation
messages: Nucleus

9915:CS
gene id: 9915:CS
uniprot id: A0A6P5BTN2
uniprot id: A0A6P5BTN9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

9915:GAPVD1
gene id: 9915:GAPVD1
uniprot id: A0A6P5CJY5
uniprot id: A0A6P5CLM9
uniprot id: A0A6P5CND8
uniprot id: A0A6P5CNE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAPVD1 family.
messages: Membrane

9915:MBD4
gene id: 9915:MBD4
uniprot id: A0A6P5DQD1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with MLH1.
messages: Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.
messages: Nucleus

9915:BCKDHA
gene id: 9915:BCKDHA
uniprot id: A0A6P5DC14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BCKDHA family.
messages: Heterotetramer of alpha and beta chains.
messages: The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).

9915:SERPINI2
gene id: 9915:SERPINI2
uniprot id: A0A6P5BEE0
names: Similarity
messages: Belongs to the serpin family.

9915:MRPL58
gene id: 9915:MRPL58
uniprot id: A0A6P5DJI4
uniprot id: A0A6P5DKN4
names: Subcellular Location Annotation
messages: Mitochondrion

9915:LYRM7
gene id: 9915:LYRM7
uniprot id: A0A6P5C3K0
uniprot id: A0A6P5C4R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

9915:TMEM50B
gene id: 9915:TMEM50B
uniprot id: A0A6P5CZD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

9915:FLT1
gene id: 9915:FLT1
uniprot id: A0A6P5CMX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9915:REEP3
gene id: 9915:REEP3
uniprot id: A0A6P5AXX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

9915:IMPA1
gene id: 9915:IMPA1
uniprot id: A0A6P5CUN9
uniprot id: A0A6P5CUX9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9915:THRAP3
gene id: 9915:THRAP3
uniprot id: A0A6P5B4G4
uniprot id: A0A6P5BPP3
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9915:MTO1
gene id: 9915:MTO1
uniprot id: A0A6P5CA10
uniprot id: A0A6P5CAH7
uniprot id: A0A6P5CBU8
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

9915:SLC25A4
gene id: 9915:SLC25A4
uniprot id: A0A6P5B925
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

9915:TMEM134
gene id: 9915:TMEM134
uniprot id: A0A6P5AVR0
uniprot id: A0A6P5AVR5
uniprot id: A0A6P5B1P8
uniprot id: A0A6P5BKS6
uniprot id: A0A6P5BKU1
uniprot id: A0A6P5BKU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Membrane

9915:METTL3
gene id: 9915:METTL3
uniprot id: A0A6P5CER5
uniprot id: A0A6P5CF75
names: Similarity
messages: Belongs to the MT-A70-like family.

9915:LOC109563926
gene id: 9915:LOC109563926
uniprot id: A0A6P5CCX8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109564796
gene id: 9915:LOC109564796
uniprot id: A0A6P5CFW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9915:LOC109554023
gene id: 9915:LOC109554023
uniprot id: A0A6P5BBB8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CKMT1A
gene id: 9915:CKMT1A
uniprot id: A0A6P5DMH2
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9915:LOC109579095
gene id: 9915:LOC109579095
uniprot id: A0A6P5E3Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM24 family.
messages: Secreted

9915:NDUFAF3
gene id: 9915:NDUFAF3
uniprot id: A0A6P5DST2
names: Function
names: Subcellular Location Annotation
messages: Essential factor for the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Membrane
messages: Mitochondrion inner membrane
messages: Nucleus

9915:LOC109573890
gene id: 9915:LOC109573890
uniprot id: A0A6P5DIH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:TSC22D1
gene id: 9915:TSC22D1
uniprot id: A0A6P5CKY4
uniprot id: A0A6P5CM98
uniprot id: A0A6P5CNG7
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

9915:FAM109B
gene id: 9915:FAM109B
uniprot id: A0A6P5BW35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Forms homodimers and heterodimers with PHETA. Interacts with OCRL and INPP5B.
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

9915:LHFPL4
gene id: 9915:LHFPL4
uniprot id: A0A6P5DP55
names: Subcellular Location Annotation
messages: Membrane

9915:CPNE6
gene id: 9915:CPNE6
uniprot id: A0A6P5CDS6
names: Similarity
messages: Belongs to the copine family.

9915:LOC109576624
gene id: 9915:LOC109576624
uniprot id: A0A6P5DR28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MITF
gene id: 9915:MITF
uniprot id: A0A6P5DP43
uniprot id: A0A6P5DP47
uniprot id: A0A6P5DQP7
uniprot id: A0A6P5DT70
uniprot id: A0A6P5DT74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

9915:ARHGEF2
gene id: 9915:ARHGEF2
uniprot id: A0A6P5AQF4
uniprot id: A0A6P5AQG9
uniprot id: A0A6P5AX48
uniprot id: A0A6P5B905
uniprot id: A0A6P5B908
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Golgi apparatus
messages: Vesicle
messages: spindle
messages: tight junction

9915:ACTRT3
gene id: 9915:ACTRT3
uniprot id: A0A6P5BE59
uniprot id: A0A6P5BRW9
names: Similarity
messages: Belongs to the actin family.

9915:TBXA2R
gene id: 9915:TBXA2R
uniprot id: A0A6P5C361
uniprot id: A0A6P5C4F1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:SLC30A1
gene id: 9915:SLC30A1
uniprot id: A0A6P5D5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9915:DDX51
gene id: 9915:DDX51
uniprot id: A0A6P5D3A0
names: Similarity
messages: Belongs to the DEAD box helicase family.

9915:CRBN
gene id: 9915:CRBN
uniprot id: A0A6P5DPI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

9915:LOC109568839
gene id: 9915:LOC109568839
uniprot id: A0A6P5CVN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SKAP2
gene id: 9915:SKAP2
uniprot id: A0A6P5BQT4
uniprot id: A0A6P5BQV0
names: Similarity
messages: Belongs to the SKAP family.

9915:PISD
gene id: 9915:PISD
uniprot id: A0A6P5D4T8
uniprot id: A0A6P5D4U3
uniprot id: A0A6P5D5B6
uniprot id: A0A6P5D656
uniprot id: A0A6P5D767
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

9915:LOC109562635
gene id: 9915:LOC109562635
uniprot id: A0A6P5C6L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:LRP5
gene id: 9915:LRP5
uniprot id: A0A6P5B0M8
uniprot id: A0A6P5BCS1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109575259
gene id: 9915:LOC109575259
uniprot id: A0A6P5DP76
names: Subcellular Location Annotation
messages: Membrane

9915:SPCS3
gene id: 9915:SPCS3
uniprot id: A0A6P5BI07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

9915:MEN1
gene id: 9915:MEN1
uniprot id: A0A6P5BJB9
names: Subcellular Location Annotation
messages: Nucleus

9915:KIF13B
gene id: 9915:KIF13B
uniprot id: A0A6P5C722
uniprot id: A0A6P5C747
uniprot id: A0A6P5C8D1
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CES4A
gene id: 9915:CES4A
uniprot id: A0A6P5D9Q5
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

9915:INSIG1
gene id: 9915:INSIG1
uniprot id: A0A6P5B997
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9915:LOC109572159
gene id: 9915:LOC109572159
uniprot id: A0A6P5DB99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109562521
gene id: 9915:LOC109562521
uniprot id: A0A6P5C6A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

9915:TFR2
gene id: 9915:TFR2
uniprot id: A0A6P5DZQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9915:ANAPC1
gene id: 9915:ANAPC1
uniprot id: A0A6P5CHM4
uniprot id: A0A6P5CI84
uniprot id: A0A6P5CJT1
names: Similarity
messages: Belongs to the APC1 family.

9915:PIGL
gene id: 9915:PIGL
uniprot id: A0A6P5DD61
uniprot id: A0A6P5DFJ3
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

9915:SGSM3
gene id: 9915:SGSM3
uniprot id: A0A6P5BVY0
uniprot id: A0A6P5BVY4
uniprot id: A0A6P5BW03
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

9915:MMP13
gene id: 9915:MMP13
uniprot id: A0A6P5CX17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
messages: Secreted

9915:GET4
gene id: 9915:GET4
uniprot id: A0A6P5E1B7
names: Similarity
messages: Belongs to the GET4 family.

9915:LOC109572181
gene id: 9915:LOC109572181
uniprot id: A0A6P5D9C4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:KCNE4
gene id: 9915:KCNE4
uniprot id: A0A6P5D5W1
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9915:LOC109569544
gene id: 9915:LOC109569544
uniprot id: A0A6P5CZK1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NCAN
gene id: 9915:NCAN
uniprot id: A0A6P5C1J5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aggrecan/versican proteoglycan family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:AQP2
gene id: 9915:AQP2
uniprot id: A0A6P5BM84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9915:LOC109561187
gene id: 9915:LOC109561187
uniprot id: A0A6P5C1M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FGF23
gene id: 9915:FGF23
uniprot id: A0A6P5BVQ9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9915:DBNDD1
gene id: 9915:DBNDD1
uniprot id: A0A6P5D9M9
uniprot id: A0A6P5D9T1
uniprot id: A0A6P5DBY9
names: Similarity
messages: Belongs to the dysbindin family.

9915:LOC109558017
gene id: 9915:LOC109558017
uniprot id: A0A6P5BRI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576623
gene id: 9915:LOC109576623
uniprot id: A0A6P5DV14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KMT2B
gene id: 9915:KMT2B
uniprot id: A0A6P5D8I3
names: Subcellular Location Annotation
messages: Nucleus

9915:FOXB1
gene id: 9915:FOXB1
uniprot id: A0A6P5CCW5
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109558584
gene id: 9915:LOC109558584
uniprot id: A0A6P5BS31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9915:DNAAF2
gene id: 9915:DNAAF2
uniprot id: A0A6P5CFD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIH1 family. Kintoun subfamily.
messages: Cytoplasm
messages: Interacts with CFAP300. Interacts with DNAI2 and HSPA1A. Interacts with DYX1C1. Interacts with PIH1D3.
messages: Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment.

9915:TFAP2E
gene id: 9915:TFAP2E
uniprot id: A0A6P5BQ43
names: Similarity
messages: Belongs to the AP-2 family.

9915:LOC109559972
gene id: 9915:LOC109559972
uniprot id: A0A6P5BWN6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:LOC109576965
gene id: 9915:LOC109576965
uniprot id: A0A6P5DW59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109556705
gene id: 9915:LOC109556705
uniprot id: A0A6P5BJ65
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:STT3A
gene id: 9915:STT3A
uniprot id: A0A6P5AUV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

9915:KIF1C
gene id: 9915:KIF1C
uniprot id: A0A6P5DEU5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109567227
gene id: 9915:LOC109567227
uniprot id: A0A6P5CN86
uniprot id: A0A6P5CRQ6
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9915:LOC109562726
gene id: 9915:LOC109562726
uniprot id: A0A6P5C742
names: Subcellular Location Annotation
messages: extracellular space

9915:FKBP4
gene id: 9915:FKBP4
uniprot id: A0A6P5BVI0
names: Subcellular Location Annotation
messages: Mitochondrion
messages: Nucleus
messages: cytoskeleton
messages: cytosol

9915:CFAP52
gene id: 9915:CFAP52
uniprot id: A0A6P5DLV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP52 family.
messages: cilium axoneme
messages: flagellum

9915:LOC109570018
gene id: 9915:LOC109570018
uniprot id: A0A6P5D053
names: Similarity
messages: Belongs to the globin family.

9915:ADD3
gene id: 9915:ADD3
uniprot id: A0A6P5ANJ9
uniprot id: A0A6P5BG80
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

9915:XPNPEP1
gene id: 9915:XPNPEP1
uniprot id: A0A6P5AP29
names: Similarity
messages: Belongs to the peptidase M24B family.

9915:EMC3
gene id: 9915:EMC3
uniprot id: A0A6P5DTC8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC3 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Membrane

9915:LOC109564415
gene id: 9915:LOC109564415
uniprot id: A0A6P5CCN3
names: Subcellular Location Annotation
messages: Membrane

9915:PTMS
gene id: 9915:PTMS
uniprot id: A0A6P5BF15
names: Similarity
messages: Belongs to the pro/parathymosin family.

9915:UBE2G2
gene id: 9915:UBE2G2
uniprot id: A0A6P5BZY5
uniprot id: A0A6P5C0X2
uniprot id: A0A6P5C0X7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:LOC109563474
gene id: 9915:LOC109563474
uniprot id: A0A6P5CAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9915:GCFC2
gene id: 9915:GCFC2
uniprot id: A0A6P5CJB6
names: Similarity
messages: Belongs to the GCF family.

9915:ARL4D
gene id: 9915:ARL4D
uniprot id: A0A6P5DIE4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9915:RIPPLY1
gene id: 9915:RIPPLY1
uniprot id: A0A6P5BL68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

9915:LEPR
gene id: 9915:LEPR
uniprot id: A0A6P5BP38
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane

9915:FAM58A
gene id: 9915:FAM58A
uniprot id: A0A6P5AYP2
uniprot id: A0A6P5AYP4
uniprot id: A0A6P5B4I0
uniprot id: A0A6P5BMD7
uniprot id: A0A6P5BME7
names: Similarity
messages: Belongs to the cyclin family. Cyclin-like FAM58 subfamily.

9915:LOC109569540
gene id: 9915:LOC109569540
uniprot id: A0A6P5D0E3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CHRM4
gene id: 9915:CHRM4
uniprot id: A0A6P5D2J2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

9915:S100A4
gene id: 9915:S100A4
uniprot id: A0A6P5BKW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9915:BAIAP2
gene id: 9915:BAIAP2
uniprot id: A0A6P5DF49
uniprot id: A0A6P5DHK0
uniprot id: A0A6P5DI33
names: Function
names: Subcellular Location Annotation
messages: Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions.
messages: Membrane
messages: cytoskeleton
messages: filopodium
messages: ruffle

9915:LOC109574079
gene id: 9915:LOC109574079
uniprot id: A0A6P5DJL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

9915:SNTG1
gene id: 9915:SNTG1
uniprot id: A0A6P5CUX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

9915:ANXA1
gene id: 9915:ANXA1
uniprot id: A0A6P5C7S6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the annexin family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Nucleus
messages: The full-length protein can bind eight Ca(2+) ions via the annexin repeats. Calcium binding causes a major conformation change that modifies dimer contacts and leads to surface exposure of the N-terminal phosphorylation sites; in the absence of Ca(2+), these sites are buried in the interior of the protein core. The N-terminal region becomes disordered in response to calcium-binding.
messages: cilium
messages: extracellular exosome
messages: extracellular space
messages: phagocytic cup
messages: secretory vesicle lumen

9915:LOC109566018
gene id: 9915:LOC109566018
uniprot id: A0A6P5CIX5
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9915:BCDIN3D
gene id: 9915:BCDIN3D
uniprot id: A0A6P5BDF6
names: Similarity
messages: Belongs to the methyltransferase superfamily.

9915:LOC109554126
gene id: 9915:LOC109554126
uniprot id: A0A6P5BJF1
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9915:LOC109558571
gene id: 9915:LOC109558571
uniprot id: A0A6P5BS27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:LOC109572199
gene id: 9915:LOC109572199
uniprot id: A0A6P5DBD5
names: Similarity
messages: Belongs to the histone H3 family.

9915:CLCA2
gene id: 9915:CLCA2
uniprot id: A0A6P5BA68
names: Similarity
messages: Belongs to the CLCR family.

9915:CPQ
gene id: 9915:CPQ
uniprot id: A0A6P5CVF3
uniprot id: A0A6P5CWP2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Carboxypeptidase that may play an important role in the hydrolysis of circulating peptides. Catalyzes the hydrolysis of dipeptides with unsubstituted terminals into amino acids. May play a role in the liberation of thyroxine hormone from its thyroglobulin (Tg) precursor.
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

9915:CA8
gene id: 9915:CA8
uniprot id: A0A6P5CVD9
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

9915:PKIB
gene id: 9915:PKIB
uniprot id: A0A6P5CAR4
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

9915:HSF1
gene id: 9915:HSF1
uniprot id: A0A6P5CVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:ITPKC
gene id: 9915:ITPKC
uniprot id: A0A6P5D9J3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

9915:MRGBP
gene id: 9915:MRGBP
uniprot id: A0A6P5CPK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

9915:LOC109576807
gene id: 9915:LOC109576807
uniprot id: A0A6P5DSY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109557628
gene id: 9915:LOC109557628
uniprot id: A0A6P5BCD2
uniprot id: A0A6P5BR41
names: Similarity
messages: Belongs to the peptidase M14 family.

9915:IL12A
gene id: 9915:IL12A
uniprot id: A0A6P5CDG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-6 superfamily.
messages: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12.
messages: Heterodimerizes with IL12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 is primarily produced by professional antigen-presenting cells (APCs) such as B-cells and dendritic cells (DCs) as well as macrophages and granulocytes and regulates T-cell and natural killer-cell responses, induces the production of interferon-gamma (IFN-gamma), favors the differentiation of T-helper 1 (Th1) cells and is an important link between innate resistance and adaptive immunity. Mechanistically, exerts its biological effects through a receptor composed of IL12R1 and IL12R2 subunits. Binding to the receptor results in the rapid tyrosine phosphorylation of a number of cellular substrates including the JAK family kinases TYK2 and JAK2. In turn, recruited STAT4 gets phosphorylated and translocates to the nucleus where it regulates cytokine/growth factor responsive genes. As part of IL-35, plays essential roles in maintaining the immune homeostasis of the liver microenvironment and functions also as an immune-suppressive cytokine. Mediates biological events through unconventional receptors composed of IL12RB2 and gp130/IL6ST heterodimers or homodimers. Signaling requires the transcription factors STAT1 and STAT4, which form a unique heterodimer that binds to distinct DNA sites.
messages: Secreted

9915:PRKRA
gene id: 9915:PRKRA
uniprot id: A0A6P5CJ30
uniprot id: A0A6P5CJK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRKRA family.
messages: perinuclear region

9915:EML4
gene id: 9915:EML4
uniprot id: A0A6P5CHX4
uniprot id: A0A6P5CIX0
uniprot id: A0A6P5CJF1
uniprot id: A0A6P5CK53
uniprot id: A0A6P5CL42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

9915:DNAH8
gene id: 9915:DNAH8
uniprot id: A0A6P5DUS4
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:FAM102B
gene id: 9915:FAM102B
uniprot id: A0A6P5BNN7
names: Similarity
messages: Belongs to the FAM102 family.

9915:LOC109577007
gene id: 9915:LOC109577007
uniprot id: A0A6P5DSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline phosphatase family.
messages: Cell membrane
messages: Membrane

9915:TM7SF2
gene id: 9915:TM7SF2
uniprot id: A0A6P5AUD6
uniprot id: A0A6P5BCN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

9915:F7
gene id: 9915:F7
uniprot id: A0A6P5CNT2
uniprot id: A0A6P5CQ14
names: Caution
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Heterodimer of a light chain and a heavy chain linked by a disulfide bond.
messages: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:BCAP29
gene id: 9915:BCAP29
uniprot id: A0A6P5BK00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a role in the export of secreted proteins in the ER.

9915:GPM6A
gene id: 9915:GPM6A
uniprot id: A0A6P5B8F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

9915:AIM1
gene id: 9915:AIM1
uniprot id: A0A6P5CB47
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9915:DDX52
gene id: 9915:DDX52
uniprot id: A0A6P5DJ80
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

9915:KIZ
gene id: 9915:KIZ
uniprot id: A0A6P5CRZ9
uniprot id: A0A6P5CVI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

9915:TNC
gene id: 9915:TNC
uniprot id: A0A6P5C9H3
uniprot id: A0A6P5C9H8
uniprot id: A0A6P5C9I7
uniprot id: A0A6P5C9V1
uniprot id: A0A6P5C9V9
uniprot id: A0A6P5C9W6
uniprot id: A0A6P5CA68
uniprot id: A0A6P5CA75
uniprot id: A0A6P5CA79
uniprot id: A0A6P5CAC4
uniprot id: A0A6P5CAD5
uniprot id: A0A6P5CBA7
uniprot id: A0A6P5CBB2
uniprot id: A0A6P5CBB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9915:NKAIN3
gene id: 9915:NKAIN3
uniprot id: A0A6P5CTH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9915:LOC109564479
gene id: 9915:LOC109564479
uniprot id: A0A6P5CCD9
uniprot id: A0A6P5CEJ8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:POLR3C
gene id: 9915:POLR3C
uniprot id: A0A6P5B0L7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9915:ARV1
gene id: 9915:ARV1
uniprot id: A0A6P5BIA0
uniprot id: A0A6P5BIM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane

9915:GATA2
gene id: 9915:GATA2
uniprot id: A0A6P5DQ12
names: Subcellular Location Annotation
messages: Nucleus

9915:ALK
gene id: 9915:ALK
uniprot id: A0A6P5CGI6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

9915:NAP1L4
gene id: 9915:NAP1L4
uniprot id: A0A6P5AU94
uniprot id: A0A6P5B0G7
uniprot id: A0A6P5BCK0
uniprot id: A0A6P5BJU1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:UNC50
gene id: 9915:UNC50
uniprot id: A0A6P5CH91
uniprot id: A0A6P5CK83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

9915:ITPRIP
gene id: 9915:ITPRIP
uniprot id: A0A6P5AVU5
uniprot id: A0A6P5BGX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

9915:LOC109557662
gene id: 9915:LOC109557662
uniprot id: A0A6P5BR31
uniprot id: A0A6P5BR58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

9915:LRP6
gene id: 9915:LRP6
uniprot id: A0A6P5BV32
uniprot id: A0A6P5BV41
uniprot id: A0A6P5BVB3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109560172
gene id: 9915:LOC109560172
uniprot id: A0A6P5BWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9915:PEX14
gene id: 9915:PEX14
uniprot id: A0A6P5D1L4
uniprot id: A0A6P5D2Q9
uniprot id: A0A6P5D402
uniprot id: A0A6P5D5D5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

9915:LOC109554762
gene id: 9915:LOC109554762
uniprot id: A0A6P5BKY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109562667
gene id: 9915:LOC109562667
uniprot id: A0A6P5C6N5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha/beta interferon family.
messages: Monomer.
messages: Secreted

9915:EID3
gene id: 9915:EID3
uniprot id: A0A6P5BU80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

9915:GFRA4
gene id: 9915:GFRA4
uniprot id: A0A6P5CTR6
names: Similarity
messages: Belongs to the GDNFR family.

9915:MADD
gene id: 9915:MADD
uniprot id: A0A6P5CXQ3
uniprot id: A0A6P5CXQ9
uniprot id: A0A6P5CXR7
uniprot id: A0A6P5CXS3
uniprot id: A0A6P5CXT2
uniprot id: A0A6P5CXT7
uniprot id: A0A6P5CYH0
uniprot id: A0A6P5CYH4
uniprot id: A0A6P5CYI0
uniprot id: A0A6P5CYN2
uniprot id: A0A6P5CYN8
uniprot id: A0A6P5CYP3
uniprot id: A0A6P5CYQ0
uniprot id: A0A6P5CYQ5
uniprot id: A0A6P5D075
uniprot id: A0A6P5D081
uniprot id: A0A6P5D087
uniprot id: A0A6P5D094
uniprot id: A0A6P5D099
uniprot id: A0A6P5D136
uniprot id: A0A6P5D143
uniprot id: A0A6P5D148
uniprot id: A0A6P5D153
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MADD family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9915:TRPC5
gene id: 9915:TRPC5
uniprot id: A0A6P5BGG5
names: Subcellular Location Annotation
messages: Membrane

9915:PRF1
gene id: 9915:PRF1
uniprot id: A0A6P5AST8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Secreted

9915:LOC109572442
gene id: 9915:LOC109572442
uniprot id: A0A6P5DAW2
names: Subcellular Location Annotation
messages: Nucleus

9915:PTPA
gene id: 9915:PTPA
uniprot id: A0A6P5CMS8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9915:CSF1R
gene id: 9915:CSF1R
uniprot id: A0A6P5C5Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane

9915:TRUB1
gene id: 9915:TRUB1
uniprot id: A0A6P5AWD9
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

9915:NT5DC1
gene id: 9915:NT5DC1
uniprot id: A0A6P5CAV0
uniprot id: A0A6P5CBI0
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

9915:OPN5
gene id: 9915:OPN5
uniprot id: A0A6P5DVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:DMBT1
gene id: 9915:DMBT1
uniprot id: A0A6P5BGK5
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109572792
gene id: 9915:LOC109572792
uniprot id: A0A6P5DD70
names: Subcellular Location Annotation
messages: Membrane

9915:TMEM182
gene id: 9915:TMEM182
uniprot id: A0A6P5CHG2
uniprot id: A0A6P5CKG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

9915:LAMTOR2
gene id: 9915:LAMTOR2
uniprot id: A0A6P5B8T6
uniprot id: A0A6P5B8U6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GAMAD family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

9915:LOC109556698
gene id: 9915:LOC109556698
uniprot id: A0A6P5B9X6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM171A2
gene id: 9915:FAM171A2
uniprot id: A0A6P5DEI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9915:CTNNBIP1
gene id: 9915:CTNNBIP1
uniprot id: A0A6P5D2C7
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9915:ZRANB2
gene id: 9915:ZRANB2
uniprot id: A0A6P5B7H1
uniprot id: A0A6P5BHQ6
uniprot id: A0A6P5BNZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: Nucleus
messages: Splice factor required for alternative splicing of TRA2B/SFRS10 transcripts. May interfere with constitutive 5'-splice site selection.

9915:TCP11
gene id: 9915:TCP11
uniprot id: A0A6P5DR87
names: Similarity
messages: Belongs to the TCP11 family.

9915:LOC109572403
gene id: 9915:LOC109572403
uniprot id: A0A6P5D8Y6
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9915:LOC109560855
gene id: 9915:LOC109560855
uniprot id: A0A6P5C078
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:WNT8A
gene id: 9915:WNT8A
uniprot id: A0A6P5C163
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:LOC109575954
gene id: 9915:LOC109575954
uniprot id: A0A6P5DRX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:HSD17B7
gene id: 9915:HSD17B7
uniprot id: A0A6P5DZU9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily.

9915:ZSCAN10
gene id: 9915:ZSCAN10
uniprot id: A0A6P5E0X2
names: Subcellular Location Annotation
messages: Nucleus

9915:FAM216B
gene id: 9915:FAM216B
uniprot id: A0A6P5CNF7
names: Similarity
messages: Belongs to the FAM216 family.

9915:TCTEX1D4
gene id: 9915:TCTEX1D4
uniprot id: A0A6P5B3Q8
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:AQP4
gene id: 9915:AQP4
uniprot id: A0A6P5DVU3
uniprot id: A0A6P5DWT0
uniprot id: A0A6P5DZE8
uniprot id: A0A6P5DZW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9915:C3
gene id: 9915:C3
uniprot id: A0A6P5C325
names: Function
names: Subcellular Location Annotation
messages: Acts as a chemoattractant for neutrophils in chronic inflammation.
messages: C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates.
messages: Secreted

9915:LOC109576098
gene id: 9915:LOC109576098
uniprot id: A0A6P5DPB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9915:HOMER3
gene id: 9915:HOMER3
uniprot id: A0A6P5C1L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9915:LOC109555109
gene id: 9915:LOC109555109
uniprot id: A0A6P5B2S8
names: Similarity
messages: Belongs to the BEX family.

9915:FUCA2
gene id: 9915:FUCA2
uniprot id: A0A6P5CCN9
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

9915:LOC109578068
gene id: 9915:LOC109578068
uniprot id: A0A6P5DWA4
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109576701
gene id: 9915:LOC109576701
uniprot id: A0A6P5DRA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC35A4
gene id: 9915:SLC35A4
uniprot id: A0A6P5C656
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9915:ARL6
gene id: 9915:ARL6
uniprot id: A0A6P5CAF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

9915:CNKSR1
gene id: 9915:CNKSR1
uniprot id: A0A6P5DDL3
names: Similarity
messages: Belongs to the CNKSR family.

9915:LOC109579106
gene id: 9915:LOC109579106
uniprot id: A0A6P5E3Z7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DAZL
gene id: 9915:DAZL
uniprot id: A0A6P5CBH8
names: Subcellular Location Annotation
messages: Cytoplasm

9915:SRC
gene id: 9915:SRC
uniprot id: A0A6P5CRT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9915:SLC35F6
gene id: 9915:SLC35F6
uniprot id: A0A6P5CKW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLC35F solute transporter family.
messages: Interacts with SLC25A5.
messages: May play a role as a nucleotide-sugar transporter.
messages: Membrane
messages: Mitochondrion

9915:GALK1
gene id: 9915:GALK1
uniprot id: A0A6P5DCS9
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9915:LOC109554099
gene id: 9915:LOC109554099
uniprot id: A0A6P5BJ39
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:PSD3
gene id: 9915:PSD3
uniprot id: A0A6P5B8Y5
names: Subcellular Location Annotation
messages: ruffle membrane

9915:FNBP1L
gene id: 9915:FNBP1L
uniprot id: A0A6P5B1W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Membrane
messages: Vesicle
messages: cell cortex
messages: cytoskeleton

9915:TIMELESS
gene id: 9915:TIMELESS
uniprot id: A0A6P5BTM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the timeless family.
messages: Nucleus

9915:SCFD1
gene id: 9915:SCFD1
uniprot id: A0A6P5DMP5
uniprot id: A0A6P5DPN5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9915:FOXE1
gene id: 9915:FOXE1
uniprot id: A0A6P5C824
names: Subcellular Location Annotation
messages: Nucleus

9915:TDGF1
gene id: 9915:TDGF1
uniprot id: A0A6P5DUA1
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PARD6A
gene id: 9915:PARD6A
uniprot id: A0A6P5DA55
uniprot id: A0A6P5DBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9915:LOC109573562
gene id: 9915:LOC109573562
uniprot id: A0A6P5DGU3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109566754
gene id: 9915:LOC109566754
uniprot id: A0A6P5CLB9
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

9915:CAMTA2
gene id: 9915:CAMTA2
uniprot id: A0A6P5DCH8
names: Similarity
names: Subunit
messages: Belongs to the CAMTA family.
messages: May interact with calmodulin.

9915:LOC109569282
gene id: 9915:LOC109569282
uniprot id: A0A6P5CVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:A2ML1
gene id: 9915:A2ML1
uniprot id: A0A6P5BB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

9915:CTSO
gene id: 9915:CTSO
uniprot id: A0A6P5D9A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9915:LOC109559516
gene id: 9915:LOC109559516
uniprot id: A0A6P5BUG7
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:LOC109574824
gene id: 9915:LOC109574824
uniprot id: A0A6P5DJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:HS2ST1
gene id: 9915:HS2ST1
uniprot id: A0A6P5B754
uniprot id: A0A6P5BNU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

9915:TSPAN1
gene id: 9915:TSPAN1
uniprot id: A0A6P5B3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:LAPTM4B
gene id: 9915:LAPTM4B
uniprot id: A0A6P5CW31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAPTM4/LAPTM5 transporter family.
messages: Cell membrane
messages: Cell projection
messages: Endomembrane system
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: multivesicular body lumen
messages: multivesicular body membrane

9915:LOC109567646
gene id: 9915:LOC109567646
uniprot id: A0A6P5CRR4
names: Similarity
messages: Belongs to the histone H2B family.

9915:LOC109576688
gene id: 9915:LOC109576688
uniprot id: A0A6P5DSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PTPRS
gene id: 9915:PTPRS
uniprot id: A0A6P5C324
uniprot id: A0A6P5C373
uniprot id: A0A6P5C478
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

9915:PPP1R9A
gene id: 9915:PPP1R9A
uniprot id: A0A6P5BAB1
uniprot id: A0A6P5BDW1
uniprot id: A0A6P5BLN9
uniprot id: A0A6P5BLP1
uniprot id: A0A6P5BRS4
uniprot id: A0A6P5BRS9
uniprot id: A0A6P5BRT1
names: Subcellular Location Annotation
messages: cytoskeleton

9915:MTFR1L
gene id: 9915:MTFR1L
uniprot id: A0A6P5DE48
uniprot id: A0A6P5DE73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9915:EYA4
gene id: 9915:EYA4
uniprot id: A0A6P5CCF4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Nucleus

9915:CPXM2
gene id: 9915:CPXM2
uniprot id: A0A6P5BH83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9915:NDST2
gene id: 9915:NDST2
uniprot id: A0A6P5AXX3
uniprot id: A0A6P5B9S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

9915:TAS2R40
gene id: 9915:TAS2R40
uniprot id: A0A6P5BDN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:RYR3
gene id: 9915:RYR3
uniprot id: A0A6P5CD57
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9915:SLC16A14
gene id: 9915:SLC16A14
uniprot id: A0A6P5D691
names: Subcellular Location Annotation
messages: Membrane

9915:ALDH18A1
gene id: 9915:ALDH18A1
uniprot id: A0A6P5ANM3
uniprot id: A0A6P5BGR8
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

9915:HBP1
gene id: 9915:HBP1
uniprot id: A0A6P5B718
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the histone H1.0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.

9915:LOC109572455
gene id: 9915:LOC109572455
uniprot id: A0A6P5DAY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109569431
gene id: 9915:LOC109569431
uniprot id: A0A6P5CXD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CADM4
gene id: 9915:CADM4
uniprot id: A0A6P5D8T2
names: Similarity
messages: Belongs to the nectin family.

9915:DYNLL1
gene id: 9915:DYNLL1
uniprot id: A0A6P5D5B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:TWISTNB
gene id: 9915:TWISTNB
uniprot id: A0A6P5B6J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

9915:LOC109562514
gene id: 9915:LOC109562514
uniprot id: A0A6P5C7P0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EPB41L5
gene id: 9915:EPB41L5
uniprot id: A0A6P5CTY6
uniprot id: A0A6P5CUY8
uniprot id: A0A6P5CXE8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Photoreceptor inner segment
messages: Plays a role in the formation and organization of tight junctions during the establishment of polarity in epithelial cells.

9915:KRT18
gene id: 9915:KRT18
uniprot id: A0A6P5BSR6
names: Similarity
messages: Belongs to the intermediate filament family.

9915:HPSE
gene id: 9915:HPSE
uniprot id: A0A6P5BZ46
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9915:TMCC3
gene id: 9915:TMCC3
uniprot id: A0A6P5BCM4
uniprot id: A0A6P5BMV7
uniprot id: A0A6P5BSH4
names: Similarity
messages: Belongs to the TEX28 family.

9915:ANG
gene id: 9915:ANG
uniprot id: A0A6P5CDR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:SUZ12
gene id: 9915:SUZ12
uniprot id: A0A6P5DGM8
uniprot id: A0A6P5DJ19
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

9915:DNAH9
gene id: 9915:DNAH9
uniprot id: A0A6P5DED5
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:DYRK4
gene id: 9915:DYRK4
uniprot id: A0A6P5BVQ4
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9915:STK10
gene id: 9915:STK10
uniprot id: A0A6P5DMT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

9915:GIMAP4
gene id: 9915:GIMAP4
uniprot id: A0A6P5BRC7
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9915:HMGB3
gene id: 9915:HMGB3
uniprot id: A0A6P5B530
uniprot id: A0A6P5BMS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9915:LOC109571517
gene id: 9915:LOC109571517
uniprot id: A0A6P5D873
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC7 family.
messages: Nucleus
messages: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.

9915:SEMA7A
gene id: 9915:SEMA7A
uniprot id: A0A6P5DM01
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CCNH
gene id: 9915:CCNH
uniprot id: A0A6P5C5R6
uniprot id: A0A6P5C5T2
uniprot id: A0A6P5C5W7
uniprot id: A0A6P5C688
uniprot id: A0A6P5C743
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

9915:BGLAP
gene id: 9915:BGLAP
uniprot id: A0A6P5AWR9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Binds strongly to apatite and calcium.
messages: Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
messages: Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium.
messages: Secreted

9915:LHX4
gene id: 9915:LHX4
uniprot id: A0A6P5D3K9
names: Subcellular Location Annotation
messages: Nucleus

9915:SF3A2
gene id: 9915:SF3A2
uniprot id: A0A6P5C3F3
names: Similarity
messages: Belongs to the SF3A2 family.

9915:PIH1D1
gene id: 9915:PIH1D1
uniprot id: A0A6P5DA93
uniprot id: A0A6P5DC31
names: Similarity
messages: Belongs to the PIH1 family.

9915:NTF3
gene id: 9915:NTF3
uniprot id: A0A6P5BVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

9915:CSTF1
gene id: 9915:CSTF1
uniprot id: A0A6P5CNQ3
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109559139
gene id: 9915:LOC109559139
uniprot id: A0A6P5BDJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9915:FER
gene id: 9915:FER
uniprot id: A0A6P5C659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: Cell membrane
messages: cytoskeleton

9915:GCH1
gene id: 9915:GCH1
uniprot id: A0A6P5CDM7
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

9915:LOC109557780
gene id: 9915:LOC109557780
uniprot id: A0A6P5BL17
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9915:MTG1
gene id: 9915:MTG1
uniprot id: A0A6P5B7B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Mitochondrion inner membrane
messages: Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity. Displays mitochondrial GTPase activity.

9915:VWCE
gene id: 9915:VWCE
uniprot id: A0A6P5B035
uniprot id: A0A6P5BJE9
uniprot id: A0A6P5BJP0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:E2F4
gene id: 9915:E2F4
uniprot id: A0A6P5DAH0
uniprot id: A0A6P5DDR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:AMBP
gene id: 9915:AMBP
uniprot id: A0A6P5CA54
uniprot id: A0A6P5CB86
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Endoplasmic reticulum
messages: In the N-terminal section; belongs to the calycin superfamily. Lipocalin family.
messages: Kunitz-type serine protease inhibitor. Has high catalytic efficiency for F10/blood coagulation factor Xa and may act as an anticoagulant by inhibiting prothrombin activation. Inhibits trypsin and mast cell CMA1/chymase and tryptase proteases.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer. Also occurs as a complex with tryptase in mast cells.
messages: Nucleus membrane
messages: cytosol
messages: extracellular matrix

9915:VIL1
gene id: 9915:VIL1
uniprot id: A0A6P5D2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

9915:SUSD2
gene id: 9915:SUSD2
uniprot id: A0A6P5D5A4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LTA
gene id: 9915:LTA
uniprot id: A0A097KV13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Cytokine that in its homotrimeric form binds to TNFRSF1A/TNFR1, TNFRSF1B/TNFBR and TNFRSF14/HVEM. In its heterotrimeric form with LTB binds to TNFRSF3/LTBR. Lymphotoxin is produced by lymphocytes and is cytotoxic for a wide range of tumor cells in vitro and in vivo.
messages: Homotrimer, and heterotrimer of either two LTB and one LTA subunits or (less prevalent) two LTA and one LTB subunits. Interacts with TNFRSF14.
messages: Membrane
messages: Secreted

9915:FMOD
gene id: 9915:FMOD
uniprot id: A0A6P5D2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

9915:SEMA3C
gene id: 9915:SEMA3C
uniprot id: A0A6P5BB75
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:BOLA2B
gene id: 9915:BOLA2B
uniprot id: A0A6P5DXN3
uniprot id: A0A6P5E1M1
names: Similarity
messages: Belongs to the BolA/IbaG family.

9915:KRT23
gene id: 9915:KRT23
uniprot id: A0A6P5DD89
names: Similarity
messages: Belongs to the intermediate filament family.

9915:ATP5I
gene id: 9915:ATP5I
uniprot id: A0A6P5BZS8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9915:NDUFB6
gene id: 9915:NDUFB6
uniprot id: A0A6P5C774
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB6 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:RRN3
gene id: 9915:RRN3
uniprot id: A0A6P5DYR5
names: Similarity
messages: Belongs to the RRN3 family.

9915:LOC109575336
gene id: 9915:LOC109575336
uniprot id: A0A6P5DLC6
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109563031
gene id: 9915:LOC109563031
uniprot id: A0A6P5C8D0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:ADCY5
gene id: 9915:ADCY5
uniprot id: A0A6P5B5X5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9915:OST4
gene id: 9915:OST4
uniprot id: A0A6P5CMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:POLR2B
gene id: 9915:POLR2B
uniprot id: A0A6P5BZE1
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

9915:ADGRA1
gene id: 9915:ADGRA1
uniprot id: A0A6P5BHB3
names: Subcellular Location Annotation
messages: Membrane

9915:PPIA
gene id: 9915:PPIA
uniprot id: A0A6P5BC23
uniprot id: A0A6P5BQX5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9915:CIAO1
gene id: 9915:CIAO1
uniprot id: A0A6P5CIE0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Component of the CIA complex. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with WT1. Interacts with FAM96A.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.

9915:INTU
gene id: 9915:INTU
uniprot id: A0A6P5D982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

9915:ARHGEF6
gene id: 9915:ARHGEF6
uniprot id: A0A6P5AX95
uniprot id: A0A6P5B330
uniprot id: A0A6P5BF17
uniprot id: A0A6P5BLN2
uniprot id: A0A6P5BLP2
uniprot id: A0A6P5BLP6
names: Subcellular Location Annotation
messages: lamellipodium

9915:SRRD
gene id: 9915:SRRD
uniprot id: A0A6P5D4J0
names: Similarity
messages: Belongs to the SRR1 family.

9915:LOC109563919
gene id: 9915:LOC109563919
uniprot id: A0A6P5CC62
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NDUFB3
gene id: 9915:NDUFB3
uniprot id: A0A6P5CWN6
uniprot id: A0A6P5CXJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

9915:LOC109576889
gene id: 9915:LOC109576889
uniprot id: A0A6P5DS50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:LIPH
gene id: 9915:LIPH
uniprot id: A0A6P5BAW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9915:ETNPPL
gene id: 9915:ETNPPL
uniprot id: A0A6P5BX46
uniprot id: A0A6P5BX68
uniprot id: A0A6P5BXM3
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9915:MAT2B
gene id: 9915:MAT2B
uniprot id: A0A6P5C650
uniprot id: A0A6P5C706
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

9915:MCUR1
gene id: 9915:MCUR1
uniprot id: A0A6P5DRD9
names: Similarity
messages: Belongs to the CCDC90 family.

9915:LOC109568334
gene id: 9915:LOC109568334
uniprot id: A0A6P5CTR5
names: Subcellular Location Annotation
messages: Golgi apparatus

9915:TSPAN3
gene id: 9915:TSPAN3
uniprot id: A0A6P5DL12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:DSEL
gene id: 9915:DSEL
uniprot id: A0A6P5DVV4
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9915:IQSEC2
gene id: 9915:IQSEC2
uniprot id: A0A6P5BM90
names: Similarity
messages: Belongs to the BRAG family.

9915:SPG21
gene id: 9915:SPG21
uniprot id: A0A6P5CEH1
names: Function
messages: May play a role as a negative regulatory factor in CD4-dependent T-cell activation.

9915:MX2
gene id: 9915:MX2
uniprot id: A0A6P5BYK2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9915:CDT1
gene id: 9915:CDT1
uniprot id: A0A6P5D6C3
names: Similarity
messages: Belongs to the Cdt1 family.

9915:PRLR
gene id: 9915:PRLR
uniprot id: A0A6P5DMZ2
uniprot id: A0A6P5DNG8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Interacts with SMARCA1. Interacts with NEK3 and VAV2 and this interaction is prolactin-dependent.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

9915:LOC109576731
gene id: 9915:LOC109576731
uniprot id: A0A6P5DV93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GPR32
gene id: 9915:GPR32
uniprot id: A0A6P5D808
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:TMEM63B
gene id: 9915:TMEM63B
uniprot id: A0A6P5DSJ9
uniprot id: A0A6P5DTM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

9915:TNFSF15
gene id: 9915:TNFSF15
uniprot id: A0A6P5CA65
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:TSPAN15
gene id: 9915:TSPAN15
uniprot id: A0A6P5ASJ4
uniprot id: A0A6P5BIY0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109554032
gene id: 9915:LOC109554032
uniprot id: A0A6P5BIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PTGER2
gene id: 9915:PTGER2
uniprot id: A0A6P5CE21
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:FDPS
gene id: 9915:FDPS
uniprot id: A0A6P5AR10
uniprot id: A0A6P5B9K0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9915:PCCA
gene id: 9915:PCCA
uniprot id: A0A6P5CMA2
uniprot id: A0A6P5CNI1
uniprot id: A0A6P5CPQ9
names: Subcellular Location Annotation
messages: Mitochondrion matrix

9915:LOC109577078
gene id: 9915:LOC109577078
uniprot id: A0A6P5DSK5
names: Similarity
messages: Belongs to the MHC class I family.

9915:PTGR1
gene id: 9915:PTGR1
uniprot id: A0A6P5CAX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer or homodimer.

9915:LAMA5
gene id: 9915:LAMA5
uniprot id: A0A6P5CQ98
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9915:LOC109556513
gene id: 9915:LOC109556513
uniprot id: A0A6P5B4J1
uniprot id: A0A6P5BPQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argonaute family. Ago subfamily.
messages: Interacts with EIF4B, IMP8, PRMT5, TNRC6A and TNRC6B. Interacts with ZFP36.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

9915:MAPK8
gene id: 9915:MAPK8
uniprot id: A0A6P5ARQ3
uniprot id: A0A6P5AYB0
uniprot id: A0A6P5BA96
uniprot id: A0A6P5BII3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

9915:TNS2
gene id: 9915:TNS2
uniprot id: A0A6P5BD19
uniprot id: A0A6P5BFJ2
uniprot id: A0A6P5BN31
uniprot id: A0A6P5BSM9
uniprot id: A0A6P5BSN1
uniprot id: A0A6P5BSR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTEN phosphatase protein family.
messages: focal adhesion

9915:RFNG
gene id: 9915:RFNG
uniprot id: A0A6P5DCS2
names: Subcellular Location Annotation
messages: Membrane

9915:HYAL3
gene id: 9915:HYAL3
uniprot id: A0A6P5DP68
uniprot id: A0A6P5DSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

9915:ETV2
gene id: 9915:ETV2
uniprot id: A0A6P5D684
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:FAM171A1
gene id: 9915:FAM171A1
uniprot id: A0A6P5CR84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

9915:SNTB1
gene id: 9915:SNTB1
uniprot id: A0A6P5CXA5
names: Subcellular Location Annotation
messages: Cell junction

9915:ITIH2
gene id: 9915:ITIH2
uniprot id: A0A6P5CUE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9915:MCCC2
gene id: 9915:MCCC2
uniprot id: A0A6P5DLT7
names: Similarity
messages: Belongs to the AccD/PCCB family.

9915:PTAFR
gene id: 9915:PTAFR
uniprot id: A0A6P5DDW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9915:KIFC1
gene id: 9915:KIFC1
uniprot id: A0A6P5DRC7
uniprot id: A0A6P5DUW4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:TRMT44
gene id: 9915:TRMT44
uniprot id: A0A6P5BWJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

9915:ALAS2
gene id: 9915:ALAS2
uniprot id: A0A6P5B589
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion inner membrane

9915:GLDC
gene id: 9915:GLDC
uniprot id: A0A6P5C7U4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvP family.
messages: Mitochondrion
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9915:YIPF4
gene id: 9915:YIPF4
uniprot id: A0A6P5CJE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

9915:GBGT1
gene id: 9915:GBGT1
uniprot id: A0A6P5CMD4
uniprot id: A0A6P5CP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9915:ELP4
gene id: 9915:ELP4
uniprot id: A0A6P5CXS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

9915:NQO2
gene id: 9915:NQO2
uniprot id: A0A6P5DUW1
uniprot id: A0A6P5DXC9
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

9915:LOC109560076
gene id: 9915:LOC109560076
uniprot id: A0A6P5BWT9
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9915:SUCNR1
gene id: 9915:SUCNR1
uniprot id: A0A6P5BSV3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:NEMF
gene id: 9915:NEMF
uniprot id: A0A6P5CEN7
uniprot id: A0A6P5CFT7
names: Similarity
messages: Belongs to the NEMF family.

9915:MYT1
gene id: 9915:MYT1
uniprot id: A0A6P5CSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

9915:SMIM18
gene id: 9915:SMIM18
uniprot id: A0A6P5BHR2
names: Subcellular Location Annotation
messages: Membrane

9915:PARL
gene id: 9915:PARL
uniprot id: A0A6P5BKD1
uniprot id: A0A6P5BQY0
names: Subcellular Location Annotation
messages: Membrane

9915:PTGER4
gene id: 9915:PTGER4
uniprot id: A0A6P5DL66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

9915:LOC109555509
gene id: 9915:LOC109555509
uniprot id: A0A6P5BMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:TRAF1
gene id: 9915:TRAF1
uniprot id: A0A6P5C9K9
uniprot id: A0A6P5C9L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9915:ACAT2
gene id: 9915:ACAT2
uniprot id: A0A6P5CTU8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9915:PRMT7
gene id: 9915:PRMT7
uniprot id: A0A6P5D7A7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

9915:LOC109555729
gene id: 9915:LOC109555729
uniprot id: A0A6P5BMZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:LOC109574821
gene id: 9915:LOC109574821
uniprot id: A0A6P5DJE8
names: Similarity
messages: Belongs to the histone H2B family.

9915:STARD6
gene id: 9915:STARD6
uniprot id: A0A6P5DUL4
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

9915:PSME1
gene id: 9915:PSME1
uniprot id: A0A6P5CEJ6
uniprot id: A0A6P5CFQ7
names: Similarity
messages: Belongs to the PA28 family.

9915:LOC109554239
gene id: 9915:LOC109554239
uniprot id: A0A6P5AZZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:WT1
gene id: 9915:WT1
uniprot id: A0A6P5CZ44
uniprot id: A0A6P5CZV2
uniprot id: A0A6P5D1P2
uniprot id: A0A6P5D2P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus speckle

9915:CHAF1B
gene id: 9915:CHAF1B
uniprot id: A0A6P5C1T8
uniprot id: A0A6P5C303
names: Subcellular Location Annotation
messages: Nucleus

9915:KIF26B
gene id: 9915:KIF26B
uniprot id: A0A6P5D268
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:CRYAB
gene id: 9915:CRYAB
uniprot id: A0A6P5D0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Nucleus

9915:PRKDC
gene id: 9915:PRKDC
uniprot id: A0A6P5CVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: nucleolus

9915:LOC109570062
gene id: 9915:LOC109570062
uniprot id: A0A6P5D236
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:THTPA
gene id: 9915:THTPA
uniprot id: A0A6P5CEM4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ThTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Hydrolase highly specific for thiamine triphosphate (ThTP).
messages: Monomer.

9915:ERO1A
gene id: 9915:ERO1A
uniprot id: A0A6P5CE15
uniprot id: A0A6P5CF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane

9915:LOC109573654
gene id: 9915:LOC109573654
uniprot id: A0A6P5DE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
messages: centrosome

9915:FGF22
gene id: 9915:FGF22
uniprot id: A0A6P5C0C3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9915:CDC42BPG
gene id: 9915:CDC42BPG
uniprot id: A0A6P5BJ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. DMPK subfamily.
messages: Cytoplasm

9915:CNNM3
gene id: 9915:CNNM3
uniprot id: A0A6P5CH18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

9915:MED4
gene id: 9915:MED4
uniprot id: A0A6P5CMX9
uniprot id: A0A6P5CPP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:LOC109560910
gene id: 9915:LOC109560910
uniprot id: A0A6P5C022
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TPK1
gene id: 9915:TPK1
uniprot id: A0A6P5B8U0
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

9915:ARF5
gene id: 9915:ARF5
uniprot id: A0A6P5BR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

9915:PRPF38A
gene id: 9915:PRPF38A
uniprot id: A0A6P5B3B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

9915:COL4A6
gene id: 9915:COL4A6
uniprot id: A0A6P5BF72
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9915:LOC109570480
gene id: 9915:LOC109570480
uniprot id: A0A6P5D1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Cell membrane
messages: Cytoplasmic form induces gene transcription inhibition.
messages: Cytoplasmic vesicle lumen
messages: Lysosome lumen
messages: Nucleus
messages: Secreted

9915:LOC109561232
gene id: 9915:LOC109561232
uniprot id: A0A6P5C0Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CNNM4
gene id: 9915:CNNM4
uniprot id: A0A6P5CJ06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

9915:DERL1
gene id: 9915:DERL1
uniprot id: A0A6P5CVY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:TRIM9
gene id: 9915:TRIM9
uniprot id: A0A6P5CH20
names: Subcellular Location Annotation
messages: cytoskeleton

9915:LOC109569224
gene id: 9915:LOC109569224
uniprot id: A0A6P5CWR5
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:LLGL2
gene id: 9915:LLGL2
uniprot id: A0A6P5DI77
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

9915:LOC109555083
gene id: 9915:LOC109555083
uniprot id: A0A6P5BLC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

9915:LOC109576944
gene id: 9915:LOC109576944
uniprot id: A0A6P5DW27
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

9915:ATP6AP2
gene id: 9915:ATP6AP2
uniprot id: A0A6P5BQ17
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

9915:PDK4
gene id: 9915:PDK4
uniprot id: A0A6P5BAC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

9915:MARS2
gene id: 9915:MARS2
uniprot id: A0A6P5CXW9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9915:GRN
gene id: 9915:GRN
uniprot id: A0A6P5DH48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the granulin family.
messages: Secreted

9915:UTS2R
gene id: 9915:UTS2R
uniprot id: A0A6P5DDC7
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

9915:TRNT1
gene id: 9915:TRNT1
uniprot id: A0A6P5DNY2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

9915:LOC109567543
gene id: 9915:LOC109567543
uniprot id: A0A6P5CS98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase CarF family.
messages: Membrane

9915:SLC6A17
gene id: 9915:SLC6A17
uniprot id: A0A6P5BNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9915:DGKB
gene id: 9915:DGKB
uniprot id: A0A6P5B6G2
uniprot id: A0A6P5BAX0
uniprot id: A0A6P5BJP4
uniprot id: A0A6P5BJP5
uniprot id: A0A6P5BQC9
uniprot id: A0A6P5BQE5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:DCC
gene id: 9915:DCC
uniprot id: A0A6P5DY74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

9915:PPRC1
gene id: 9915:PPRC1
uniprot id: A0A6P5E0F6
uniprot id: A0A6P5E118
uniprot id: A0A6P5E3H3
uniprot id: A0A6P5E3H8
uniprot id: A0A6P5E3Y3
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109558363
gene id: 9915:LOC109558363
uniprot id: A0A6P5BLU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554074
gene id: 9915:LOC109554074
uniprot id: A0A6P5AT64
uniprot id: A0A6P5BBG2
uniprot id: A0A6P5BJC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

9915:CDKL4
gene id: 9915:CDKL4
uniprot id: A0A6P5CHV8
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:PLCB4
gene id: 9915:PLCB4
uniprot id: A0A6P5CQU1
uniprot id: A0A6P5CRX4
uniprot id: A0A6P5CUA7
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9915:PPP2R2B
gene id: 9915:PPP2R2B
uniprot id: A0A6P5C550
uniprot id: A0A6P5C5A2
uniprot id: A0A6P5C6J5
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

9915:LOC109576774
gene id: 9915:LOC109576774
uniprot id: A0A6P5DRT3
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9915:AP4S1
gene id: 9915:AP4S1
uniprot id: A0A6P5DMP7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

9915:BAX
gene id: 9915:BAX
uniprot id: A0A6P5D6N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

9915:LBX2
gene id: 9915:LBX2
uniprot id: A0A6P5CHP0
names: Subcellular Location Annotation
messages: Nucleus

9915:CLDN5
gene id: 9915:CLDN5
uniprot id: A0A6P5D7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:BAZ1B
gene id: 9915:BAZ1B
uniprot id: A0A6P5E161
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109554400
gene id: 9915:LOC109554400
uniprot id: A0A6P5BJZ4
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9915:PIK3CB
gene id: 9915:PIK3CB
uniprot id: A0A6P5BVS7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9915:ARID1B
gene id: 9915:ARID1B
uniprot id: A0A6P5CC23
names: Subcellular Location Annotation
messages: Nucleus

9915:NRXN3
gene id: 9915:NRXN3
uniprot id: A0A6P5CG44
uniprot id: A0A6P5CG49
uniprot id: A0A6P5CG54
uniprot id: A0A6P5CG59
uniprot id: A0A6P5CGS3
uniprot id: A0A6P5CGS8
uniprot id: A0A6P5CGT1
uniprot id: A0A6P5CGT9
uniprot id: A0A6P5CHD1
uniprot id: A0A6P5CHD5
uniprot id: A0A6P5CHD9
uniprot id: A0A6P5CHE6
uniprot id: A0A6P5CHT1
uniprot id: A0A6P5CHT9
uniprot id: A0A6P5CHU2
uniprot id: A0A6P5CHU6
uniprot id: A0A6P5CIZ3
uniprot id: A0A6P5CIZ8
uniprot id: A0A6P5CJ03
uniprot id: A0A6P5CJ08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:COPS8
gene id: 9915:COPS8
uniprot id: A0A6P5BPU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

9915:SLC12A7
gene id: 9915:SLC12A7
uniprot id: A0A6P5DKI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

9915:TPST1
gene id: 9915:TPST1
uniprot id: A0A6P5DZI5
uniprot id: A0A6P5E3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

9915:GAD1
gene id: 9915:GAD1
uniprot id: A0A6P5DUE3
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9915:FGB
gene id: 9915:FGB
uniprot id: A0A6P5D7G1
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

9915:LOC109565959
gene id: 9915:LOC109565959
uniprot id: A0A6P5CIQ1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9915:SIRT5
gene id: 9915:SIRT5
uniprot id: A0A6P5DUR5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Binds 1 zinc ion per subunit.
messages: In contrast to class I sirtuins, class III sirtuins have only weak deacetylase activity. Difference in substrate specificity is probably due to a larger hydrophobic pocket with 2 residues (Tyr-102 and Arg-105) that bind to malonylated and succinylated substrates and define the specificity.
messages: Mitochondrion
messages: Monomer. Homodimer. Interacts with CPS1.
messages: NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Modulates ketogenesis through the desuccinylation and activation of HMGCS2. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. Can deacetylate cytochrome c (CYCS) and a number of other proteins in vitro such as Uox.
messages: Nucleus
messages: cytosol

9915:UCK1
gene id: 9915:UCK1
uniprot id: A0A6P5CLS1
uniprot id: A0A6P5CM71
names: Similarity
messages: Belongs to the uridine kinase family.

9915:SRSF2
gene id: 9915:SRSF2
uniprot id: A0A6P5DDT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

9915:HCFC1
gene id: 9915:HCFC1
uniprot id: A0A6P5AX70
names: Subcellular Location Annotation
messages: Nucleus

9915:SCN11A
gene id: 9915:SCN11A
uniprot id: A0A6P5DQP3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9915:ALDH7A1
gene id: 9915:ALDH7A1
uniprot id: A0A6P5C3K1
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

9915:AMDHD1
gene id: 9915:AMDHD1
uniprot id: A0A6P5BAY4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

9915:RARRES2
gene id: 9915:RARRES2
uniprot id: A0A6P5BCW3
names: Subcellular Location Annotation
messages: Secreted

9915:VPS25
gene id: 9915:VPS25
uniprot id: A0A6P5DJQ9
names: Similarity
messages: Belongs to the VPS25 family.

9915:ARHGEF12
gene id: 9915:ARHGEF12
uniprot id: A0A6P5CXU9
uniprot id: A0A6P5CZI4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

9915:KRTCAP2
gene id: 9915:KRTCAP2
uniprot id: A0A6P5AY60
uniprot id: A0A6P5BA27
uniprot id: A0A6P5BI21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRTCAP2 family.
messages: Membrane

9915:MTMR6
gene id: 9915:MTMR6
uniprot id: A0A6P5CQ47
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9915:CCR7
gene id: 9915:CCR7
uniprot id: A0A6P5DK05
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:CASR
gene id: 9915:CASR
uniprot id: A0A6P5AZW2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:FAM228B
gene id: 9915:FAM228B
uniprot id: A0A6P5CL10
names: Similarity
messages: Belongs to the FAM228 family.

9915:LOC109573730
gene id: 9915:LOC109573730
uniprot id: A0A6P5DH07
names: Subcellular Location Annotation
messages: Nucleus

9915:NEIL1
gene id: 9915:NEIL1
uniprot id: A0A6P5DL27
uniprot id: A0A6P5DMG5
uniprot id: A0A6P5DPG6
names: Similarity
messages: Belongs to the FPG family.

9915:CACNG5
gene id: 9915:CACNG5
uniprot id: A0A6P5DKI8
names: Similarity
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.

9915:SLC26A7
gene id: 9915:SLC26A7
uniprot id: A0A6P5CX32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

9915:SMOC1
gene id: 9915:SMOC1
uniprot id: A0A6P5CFM1
uniprot id: A0A6P5CGU9
uniprot id: A0A6P5CH79
uniprot id: A0A6P5CIE2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109576955
gene id: 9915:LOC109576955
uniprot id: A0A6P5DRY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PHLDA2
gene id: 9915:PHLDA2
uniprot id: A0A6P5BBR0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109569353
gene id: 9915:LOC109569353
uniprot id: A0A6P5CWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569342
gene id: 9915:LOC109569342
uniprot id: A0A6P5CX23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569292
gene id: 9915:LOC109569292
uniprot id: A0A6P5CVY7
uniprot id: A0A6P5CWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

9915:LOC109571864
gene id: 9915:LOC109571864
uniprot id: A0A6P5D6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:RAF1
gene id: 9915:RAF1
uniprot id: A0A6P5DSH8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

9915:LOC109569311
gene id: 9915:LOC109569311
uniprot id: A0A6P5CWZ1
names: Subcellular Location Annotation
messages: Membrane

9915:FOXN2
gene id: 9915:FOXN2
uniprot id: A0A6P5CI29
names: Subcellular Location Annotation
messages: Nucleus

9915:MAPT
gene id: 9915:MAPT
uniprot id: A0A6P5DE83
uniprot id: A0A6P5DE90
uniprot id: A0A6P5DE94
uniprot id: A0A6P5DEA1
uniprot id: A0A6P5DFY3
uniprot id: A0A6P5DFY6
uniprot id: A0A6P5DFY9
uniprot id: A0A6P5DGN2
uniprot id: A0A6P5DGN9
uniprot id: A0A6P5DHA1
uniprot id: A0A6P5DHA6
names: Subcellular Location Annotation
messages: Membrane
messages: axon
messages: cytoskeleton
messages: cytosol

9915:NDUFB1
gene id: 9915:NDUFB1
uniprot id: A0A6P5DLI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:CRYBB3
gene id: 9915:CRYBB3
uniprot id: A0A6P5D3P3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9915:AEBP1
gene id: 9915:AEBP1
uniprot id: A0A6P5BQY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9915:SLC25A40
gene id: 9915:SLC25A40
uniprot id: A0A6P5BB43
uniprot id: A0A6P5BQG3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial transporter required for glutathione import into mitochondria. Glutathione, which plays key roles in oxidative metabolism, is produced exclusively in the cytosol and is imported in many organelles. Mitochondrial glutathione is required for the activity and stability of proteins containing iron-sulfur clusters, as well as erythropoiesis.
messages: Mitochondrion inner membrane

9915:MICAL1
gene id: 9915:MICAL1
uniprot id: A0A6P5CBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Cytoplasm

9915:KCNH7
gene id: 9915:KCNH7
uniprot id: A0A6P5CMP4
names: Subcellular Location Annotation
messages: Membrane

9915:DPYD
gene id: 9915:DPYD
uniprot id: A0A6P5BNP0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dihydropyrimidine dehydrogenase family.
messages: Binds 4 [4Fe-4S] clusters. Contains approximately 16 iron atoms per subunit.
messages: Involved in pyrimidine base degradation. Catalyzes the reduction of uracil and thymine.

9915:RIN2
gene id: 9915:RIN2
uniprot id: A0A6P5CQ55
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

9915:SEMA4C
gene id: 9915:SEMA4C
uniprot id: A0A6P5CIJ3
uniprot id: A0A6P5CK46
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TMEM97
gene id: 9915:TMEM97
uniprot id: A0A6P5DH73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TMEM97/sigma-2 receptor family.
messages: Endoplasmic reticulum membrane
messages: Interacts with NPC1.
messages: Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

9915:TMEM206
gene id: 9915:TMEM206
uniprot id: A0A6P5D5J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

9915:SLC35F2
gene id: 9915:SLC35F2
uniprot id: A0A6P5AWT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9915:EXOSC2
gene id: 9915:EXOSC2
uniprot id: A0A6P5CKF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

9915:AIDA
gene id: 9915:AIDA
uniprot id: A0A6P5D155
names: Similarity
messages: Belongs to the AIDA family.

9915:CRYGS
gene id: 9915:CRYGS
uniprot id: A0A6P5BQB5
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9915:IFNK
gene id: 9915:IFNK
uniprot id: A0A6P5C782
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:SS18L1
gene id: 9915:SS18L1
uniprot id: A0A6P5CPM5
uniprot id: A0A6P5CQX4
names: Similarity
messages: Belongs to the SS18 family.

9915:MECP2
gene id: 9915:MECP2
uniprot id: A0A6P5AX66
uniprot id: A0A6P5BEZ1
uniprot id: A0A6P5BLK8
names: Function
names: Subcellular Location Annotation
messages: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
messages: Nucleus

9915:TMPRSS3
gene id: 9915:TMPRSS3
uniprot id: A0A6P5CDD6
uniprot id: A0A6P5CEK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SERPINE1
gene id: 9915:SERPINE1
uniprot id: A0A6P5DZZ6
names: Similarity
messages: Belongs to the serpin family.

9915:APPL2
gene id: 9915:APPL2
uniprot id: A0A6P5BU94
uniprot id: A0A6P5BUC1
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

9915:HYAL1
gene id: 9915:HYAL1
uniprot id: A0A6P5DNK9
uniprot id: A0A6P5DQ31
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9915:CASC1
gene id: 9915:CASC1
uniprot id: A0A6P5BUS8
uniprot id: A0A6P5BUS9
uniprot id: A0A6P5BUT8
uniprot id: A0A6P5BV12
names: Similarity
messages: Belongs to the DNAI7 family.

9915:FAM49A
gene id: 9915:FAM49A
uniprot id: A0A6P5CLY4
uniprot id: A0A6P5CMV1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9915:MMP17
gene id: 9915:MMP17
uniprot id: A0A6P5D9H1
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:CLDN19
gene id: 9915:CLDN19
uniprot id: A0A6P5B8Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:LOC109575140
gene id: 9915:LOC109575140
uniprot id: A0A6P5DLP1
names: Subcellular Location Annotation
messages: Membrane

9915:CLDN17
gene id: 9915:CLDN17
uniprot id: A0A6P5CB13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:LOC109560876
gene id: 9915:LOC109560876
uniprot id: A0A6P5C0Z2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109564207
gene id: 9915:LOC109564207
uniprot id: A0A6P5CCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109575087
gene id: 9915:LOC109575087
uniprot id: A0A6P5DNU6
names: Function
messages: Cadherins are calcium-dependent cell adhesion proteins.

9915:LOXL1
gene id: 9915:LOXL1
uniprot id: A0A6P5DMI7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9915:LOC109553212
gene id: 9915:LOC109553212
uniprot id: A0A6P5AWG2
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9915:TMED5
gene id: 9915:TMED5
uniprot id: A0A6P5BNQ2
uniprot id: A0A6P5BNS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Interacts with TMED9 and TMED10.
messages: Membrane
messages: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Required for the maintenance of the Golgi apparatus; involved in protein exchange between Golgi stacks during assembly. Probably not required for COPI-vesicle-mediated retrograde transport.
messages: cis-Golgi network membrane

9915:LOC109554182
gene id: 9915:LOC109554182
uniprot id: A0A6P5BJ80
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:MRPL11
gene id: 9915:MRPL11
uniprot id: A0A6P5AVN9
uniprot id: A0A6P5BDV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

9915:EPC1
gene id: 9915:EPC1
uniprot id: A0A6P5CRJ3
uniprot id: A0A6P5CSZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

9915:LOC109573591
gene id: 9915:LOC109573591
uniprot id: A0A6P5DG95
names: Similarity
messages: Belongs to the BTG family.

9915:LOC109568850
gene id: 9915:LOC109568850
uniprot id: A0A6P5CVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MRPL2
gene id: 9915:MRPL2
uniprot id: A0A6P5DS82
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

9915:FAM20A
gene id: 9915:FAM20A
uniprot id: A0A6P5DCV6
names: Similarity
messages: Belongs to the FAM20 family.

9915:CACNB2
gene id: 9915:CACNB2
uniprot id: A0A6P5CSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

9915:LRP8
gene id: 9915:LRP8
uniprot id: A0A6P5B364
uniprot id: A0A6P5B7X9
uniprot id: A0A6P5B7Y4
uniprot id: A0A6P5BI17
uniprot id: A0A6P5BP56
uniprot id: A0A6P5BP58
uniprot id: A0A6P5BP84
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:RHOT1
gene id: 9915:RHOT1
uniprot id: A0A6P5DFE6
uniprot id: A0A6P5DFE8
uniprot id: A0A6P5DFE9
uniprot id: A0A6P5DFF2
uniprot id: A0A6P5DH08
uniprot id: A0A6P5DHT8
uniprot id: A0A6P5DID8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

9915:LOC109555102
gene id: 9915:LOC109555102
uniprot id: A0A6P5BES7
names: Similarity
messages: Belongs to the GPRASP family.

9915:LOC109553148
gene id: 9915:LOC109553148
uniprot id: A0A6P5B7Z6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9915:TUFM
gene id: 9915:TUFM
uniprot id: A0A6P5DWX7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

9915:VPS16
gene id: 9915:VPS16
uniprot id: A0A6P5CPT6
uniprot id: A0A6P5CRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS16 family.
messages: Early endosome
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes.
messages: Vesicle

9915:FAM221B
gene id: 9915:FAM221B
uniprot id: A0A6P5C8B2
names: Similarity
messages: Belongs to the FAM221 family.

9915:LAMTOR1
gene id: 9915:LAMTOR1
uniprot id: A0A6P5CVP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

9915:CAP2
gene id: 9915:CAP2
uniprot id: A0A6P5DU83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

9915:TARSL2
gene id: 9915:TARSL2
uniprot id: A0A6P5DKI1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

9915:RRP7A
gene id: 9915:RRP7A
uniprot id: A0A6P5BWB8
names: Similarity
messages: Belongs to the RRP7 family.

9915:TAF4
gene id: 9915:TAF4
uniprot id: A0A6P5CNI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

9915:ZIM2
gene id: 9915:ZIM2
uniprot id: A0A6P5DAV7
names: Subcellular Location Annotation
messages: Nucleus

9915:PDGFRB
gene id: 9915:PDGFRB
uniprot id: A0A6P5C590
uniprot id: A0A6P5C5B8
uniprot id: A0A6P5C5R0
uniprot id: A0A6P5C6N9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Interacts with homodimeric PDGFB and PDGFD, and with heterodimers formed by PDGFA and PDGFB.
messages: Lysosome lumen
messages: Membrane
messages: Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.
messages: Vesicle

9915:RIMBP2
gene id: 9915:RIMBP2
uniprot id: A0A6P5D7A5
names: Similarity
messages: Belongs to the RIMBP family.

9915:SYNJ2
gene id: 9915:SYNJ2
uniprot id: A0A6P5CAK2
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

9915:LOC109571832
gene id: 9915:LOC109571832
uniprot id: A0A6P5D6T9
names: Subcellular Location Annotation
messages: Membrane

9915:AQR
gene id: 9915:AQR
uniprot id: A0A6P5CGE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWF11 family.
messages: Identified in the spliceosome C complex. Component of the XAB2 complex, a multimeric protein complex composed of XAB2, PRPF19, AQR, ZNF830, ISY1, and PPIE.
messages: Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
messages: Nucleus

9915:SPPL2B
gene id: 9915:SPPL2B
uniprot id: A0A6P5C3K8
uniprot id: A0A6P5C4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Endosome membrane
messages: Lysosome membrane
messages: Membrane

9915:ESRRG
gene id: 9915:ESRRG
uniprot id: A0A6P5D2N0
uniprot id: A0A6P5D5X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9915:COL4A5
gene id: 9915:COL4A5
uniprot id: A0A6P5B4A9
uniprot id: A0A6P5BMA7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9915:LOC109556740
gene id: 9915:LOC109556740
uniprot id: A0A6P5BQ25
names: Similarity
messages: Belongs to the LCE family.

9915:EPS8L3
gene id: 9915:EPS8L3
uniprot id: A0A6P5BAN5
names: Similarity
messages: Belongs to the EPS8 family.

9915:OSBPL7
gene id: 9915:OSBPL7
uniprot id: A0A6P5DIA1
names: Similarity
messages: Belongs to the OSBP family.

9915:EMC8
gene id: 9915:EMC8
uniprot id: A0A6P5D7V7
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

9915:LOC109564524
gene id: 9915:LOC109564524
uniprot id: A0A6P5CES8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:THOC5
gene id: 9915:THOC5
uniprot id: A0A6P5D4Q3
uniprot id: A0A6P5D726
uniprot id: A0A6P5D8K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

9915:PPP3R1
gene id: 9915:PPP3R1
uniprot id: A0A6P5CIX1
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

9915:PLSCR3
gene id: 9915:PLSCR3
uniprot id: A0A6P5DKJ4
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9915:IL36G
gene id: 9915:IL36G
uniprot id: A0A6P5CJG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9915:GRWD1
gene id: 9915:GRWD1
uniprot id: A0A6P5DDC1
names: Subcellular Location Annotation
messages: Nucleus

9915:SAXO1
gene id: 9915:SAXO1
uniprot id: A0A6P5C687
names: Similarity
messages: Belongs to the FAM154 family.

9915:LOC109563249
gene id: 9915:LOC109563249
uniprot id: A0A6P5C900
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9915:RPS6KA5
gene id: 9915:RPS6KA5
uniprot id: A0A6P5CHK0
uniprot id: A0A6P5CHY8
uniprot id: A0A6P5CJ93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
messages: Cytoplasm

9915:GABARAPL1
gene id: 9915:GABARAPL1
uniprot id: A0A6P5BV67
names: Similarity
messages: Belongs to the ATG8 family.

9915:JUND
gene id: 9915:JUND
uniprot id: A0A6P5C1C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

9915:UBE2M
gene id: 9915:UBE2M
uniprot id: A0A6P5D7K0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:UEVLD
gene id: 9915:UEVLD
uniprot id: A0A6P5B127
uniprot id: A0A6P5BKD0
uniprot id: A0A6P5BKE1
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

9915:TMEM107
gene id: 9915:TMEM107
uniprot id: A0A6P5DHX2
uniprot id: A0A6P5DJB9
names: Subcellular Location Annotation
messages: Membrane

9915:G6PC3
gene id: 9915:G6PC3
uniprot id: A0A6P5DIF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9915:SCAMP5
gene id: 9915:SCAMP5
uniprot id: A0A6P5DQY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

9915:LOC109560425
gene id: 9915:LOC109560425
uniprot id: A0A6P5BYI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

9915:ENDOG
gene id: 9915:ENDOG
uniprot id: A0A6P5CLL8
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

9915:LOC109561325
gene id: 9915:LOC109561325
uniprot id: A0A6P5C203
names: Similarity
messages: Belongs to the histone H2B family.

9915:WARS2
gene id: 9915:WARS2
uniprot id: A0A6P5B0S2
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9915:LOC109558734
gene id: 9915:LOC109558734
uniprot id: A0A6P5BS62
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PWP2
gene id: 9915:PWP2
uniprot id: A0A6P5C1G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PWP2 family.
messages: nucleolus

9915:NMD3
gene id: 9915:NMD3
uniprot id: A0A6P5BS45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

9915:EHF
gene id: 9915:EHF
uniprot id: A0A6P5CZL7
uniprot id: A0A6P5CZX7
uniprot id: A0A6P5D1F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:LOC109569245
gene id: 9915:LOC109569245
uniprot id: A0A6P5CZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NR2C2
gene id: 9915:NR2C2
uniprot id: A0A6P5DNZ9
uniprot id: A0A6P5DS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:KCNA7
gene id: 9915:KCNA7
uniprot id: A0A6P5D6Z1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109560526
gene id: 9915:LOC109560526
uniprot id: A0A6P5BYL5
uniprot id: A0A6P5BZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9915:DUSP1
gene id: 9915:DUSP1
uniprot id: A0A6P5DK53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

9915:SMOC2
gene id: 9915:SMOC2
uniprot id: A0A6P5CBN8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MBTPS1
gene id: 9915:MBTPS1
uniprot id: A0A6P5D9M4
uniprot id: A0A6P5DBY4
names: Similarity
messages: Belongs to the peptidase S8 family.

9915:PRDM10
gene id: 9915:PRDM10
uniprot id: A0A6P5AVG8
uniprot id: A0A6P5BKL0
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9915:LOC109578108
gene id: 9915:LOC109578108
uniprot id: A0A6P5E0L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear transition protein 2 family.
messages: Nucleus
messages: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.

9915:ZEB2
gene id: 9915:ZEB2
uniprot id: A0A6P5CRI7
uniprot id: A0A6P5CSJ5
names: Similarity
messages: Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

9915:TRAPPC11
gene id: 9915:TRAPPC11
uniprot id: A0A6P5AX61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPPC11 family.
messages: Involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage.
messages: cis-Golgi network

9915:LRP1B
gene id: 9915:LRP1B
uniprot id: A0A6P5DP83
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109558687
gene id: 9915:LOC109558687
uniprot id: A0A6P5BS65
names: Similarity
messages: Belongs to the intermediate filament family.

9915:SEZ6L
gene id: 9915:SEZ6L
uniprot id: A0A6P5D586
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SLC47A2
gene id: 9915:SLC47A2
uniprot id: A0A6P5DD97
uniprot id: A0A6P5DGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

9915:AKAP9
gene id: 9915:AKAP9
uniprot id: A0A6P5B9C2
names: Subcellular Location Annotation
messages: centrosome

9915:LOC109555620
gene id: 9915:LOC109555620
uniprot id: A0A6P5AZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:LOC109576720
gene id: 9915:LOC109576720
uniprot id: A0A6P5DSR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SPTB
gene id: 9915:SPTB
uniprot id: A0A6P5CI74
names: Similarity
messages: Belongs to the spectrin family.

9915:IFT43
gene id: 9915:IFT43
uniprot id: A0A6P5CGP0
names: Similarity
messages: Belongs to the IFT43 family.

9915:LOC109561253
gene id: 9915:LOC109561253
uniprot id: A0A6P5C0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CDK5RAP2
gene id: 9915:CDK5RAP2
uniprot id: A0A6P5C9K1
uniprot id: A0A6P5C9Y1
uniprot id: A0A6P5CA88
uniprot id: A0A6P5CAE5
uniprot id: A0A6P5CBC2
uniprot id: A0A6P5CBC5
names: Subcellular Location Annotation
messages: centrosome

9915:PDPR
gene id: 9915:PDPR
uniprot id: A0A6P5DBE8
names: Similarity
messages: Belongs to the GcvT family.

9915:CFAP36
gene id: 9915:CFAP36
uniprot id: A0A6P5CIC0
uniprot id: A0A6P5CJ88
uniprot id: A0A6P5CLG8
names: Similarity
messages: Belongs to the CFAP36 family.

9915:SF3B3
gene id: 9915:SF3B3
uniprot id: A0A6P5D9S0
names: Subcellular Location Annotation
messages: Nucleus

9915:E2F6
gene id: 9915:E2F6
uniprot id: A0A6P5CJJ5
uniprot id: A0A6P5CMX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:INPPL1
gene id: 9915:INPPL1
uniprot id: A0A6P5CYK2
uniprot id: A0A6P5D040
uniprot id: A0A6P5D0Z6
names: Similarity
names: Subcellular Location Annotation
messages: Basal cell membrane
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane
messages: Nucleus speckle
messages: filopodium
messages: lamellipodium
messages: spindle pole

9915:SPRN
gene id: 9915:SPRN
uniprot id: A0A6P5AWI7
names: Function
names: Similarity
messages: Belongs to the SPRN family.
messages: Prion-like protein that has PrP(C)-like neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

9915:LOC109564515
gene id: 9915:LOC109564515
uniprot id: A0A6P5CDZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NOTCH3
gene id: 9915:NOTCH3
uniprot id: A0A6P5C2V9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOTCH family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus

9915:ADORA2A
gene id: 9915:ADORA2A
uniprot id: A0A6P5D314
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9915:OVOL1
gene id: 9915:OVOL1
uniprot id: A0A6P5BKZ2
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109565370
gene id: 9915:LOC109565370
uniprot id: A0A6P5CG03
uniprot id: A0A6P5CIV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:SKIL
gene id: 9915:SKIL
uniprot id: A0A6P5BRS8
names: Similarity
messages: Belongs to the SKI family.

9915:LOC109576397
gene id: 9915:LOC109576397
uniprot id: A0A6P5DRS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:LOC109554650
gene id: 9915:LOC109554650
uniprot id: A0A6P5BE14
names: Subcellular Location Annotation
messages: Membrane

9915:OVCH2
gene id: 9915:OVCH2
uniprot id: A0A6P5D333
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109569551
gene id: 9915:LOC109569551
uniprot id: A0A6P5CZL9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:VAX2
gene id: 9915:VAX2
uniprot id: A0A6P5CHN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

9915:DUSP27
gene id: 9915:DUSP27
uniprot id: A0A6P5DVR9
uniprot id: A0A6P5DVS5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9915:CDC37
gene id: 9915:CDC37
uniprot id: A0A6P5C293
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

9915:SAR1A
gene id: 9915:SAR1A
uniprot id: A0A6P5AY81
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

9915:TPRG1
gene id: 9915:TPRG1
uniprot id: A0A6P5BJA8
names: Similarity
messages: Belongs to the TPRG1 family.

9915:LOC109554651
gene id: 9915:LOC109554651
uniprot id: A0A6P5AVT5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LIN9
gene id: 9915:LIN9
uniprot id: A0A6P5D2V1
names: Similarity
messages: Belongs to the lin-9 family.

9915:LOC109553251
gene id: 9915:LOC109553251
uniprot id: A0A6P5APQ8
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:KLHL15
gene id: 9915:KLHL15
uniprot id: A0A6P5AY52
names: Subcellular Location Annotation
messages: Nucleus

9915:ACP5
gene id: 9915:ACP5
uniprot id: A0A6P5C2R3
names: Cofactor
messages: Binds 2 iron ions per subunit.

9915:KPNA6
gene id: 9915:KPNA6
uniprot id: A0A6P5DAY8
names: Function
names: Similarity
messages: Belongs to the importin alpha family.
messages: Functions in nuclear protein import.

9915:LOC109573382
gene id: 9915:LOC109573382
uniprot id: A0A6P5DCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9915:PIR
gene id: 9915:PIR
uniprot id: A0A6P5AYI7
uniprot id: A0A6P5BFX8
uniprot id: A0A6P5BMA5
names: Similarity
messages: Belongs to the pirin family.

9915:PRODH2
gene id: 9915:PRODH2
uniprot id: A0A6P5DAI2
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

9915:LOC109558461
gene id: 9915:LOC109558461
uniprot id: A0A6P5BLY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NIPA1
gene id: 9915:NIPA1
uniprot id: A0A6P5CED4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9915:LOC109571322
gene id: 9915:LOC109571322
uniprot id: A0A6P5D4R8
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

9915:POT1
gene id: 9915:POT1
uniprot id: A0A6P5BQZ0
uniprot id: A0A6P5BQZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

9915:CCL25
gene id: 9915:CCL25
uniprot id: A0A6P5C2Q2
uniprot id: A0A6P5C2W7
names: Similarity
messages: Belongs to the intercrine beta (chemokine CC) family.

9915:LOC109564488
gene id: 9915:LOC109564488
uniprot id: A0A6P5CCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ITPR2
gene id: 9915:ITPR2
uniprot id: A0A6P5BS02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9915:HSPA2
gene id: 9915:HSPA2
uniprot id: A0A6P5CGM6
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9915:TRIQK
gene id: 9915:TRIQK
uniprot id: A0A6P5CTY1
uniprot id: A0A6P5CUX4
uniprot id: A0A6P5CWG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIQK family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:MTMR9
gene id: 9915:MTMR9
uniprot id: A0A6P5C6W1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9915:FAM160B1
gene id: 9915:FAM160B1
uniprot id: A0A6P5AVQ0
names: Similarity
messages: Belongs to the FHIP family.

9915:SERPINB12
gene id: 9915:SERPINB12
uniprot id: A0A6P5DX45
names: Similarity
messages: Belongs to the serpin family.

9915:YY2
gene id: 9915:YY2
uniprot id: A0A6P5B3B1
names: Similarity
messages: Belongs to the YY transcription factor family.

9915:LOC109562515
gene id: 9915:LOC109562515
uniprot id: A0A6P5C6P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568901
gene id: 9915:LOC109568901
uniprot id: A0A6P5CVT5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC25A42
gene id: 9915:SLC25A42
uniprot id: A0A6P5C093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:LOC109553230
gene id: 9915:LOC109553230
uniprot id: A0A6P5AWI0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:NHP2
gene id: 9915:NHP2
uniprot id: A0A6P5C5C3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9915:LOC109555786
gene id: 9915:LOC109555786
uniprot id: A0A6P5BN44
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9915:BRINP2
gene id: 9915:BRINP2
uniprot id: A0A6P5D0H3
names: Similarity
messages: Belongs to the BRINP family.

9915:FGFR4
gene id: 9915:FGFR4
uniprot id: A0A6P5C3X8
uniprot id: A0A6P5C560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Cell membrane
messages: Membrane

9915:GABRA5
gene id: 9915:GABRA5
uniprot id: A0A6P5DNP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:CLCN1
gene id: 9915:CLCN1
uniprot id: A0A6P5BCR7
uniprot id: A0A6P5BR66
uniprot id: A0A6P5BRA5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109563470
gene id: 9915:LOC109563470
uniprot id: A0A6P5CBF6
names: Similarity
messages: Belongs to the LCA5 family.

9915:PTPN14
gene id: 9915:PTPN14
uniprot id: A0A6P5D141
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9915:CLEC12B
gene id: 9915:CLEC12B
uniprot id: A0A6P5BES4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:SLC15A1
gene id: 9915:SLC15A1
uniprot id: A0A6P5CNF3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9915:PMM2
gene id: 9915:PMM2
uniprot id: A0A6P5E0D7
uniprot id: A0A6P5E2W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9915:LOC109569500
gene id: 9915:LOC109569500
uniprot id: A0A6P5CXK9
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9915:HMGN2
gene id: 9915:HMGN2
uniprot id: A0A6P5DF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9915:LOC109557629
gene id: 9915:LOC109557629
uniprot id: A0A6P5BKM9
names: Similarity
messages: Belongs to the peptidase M14 family.

9915:CD63
gene id: 9915:CD63
uniprot id: A0A6P5BTW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Cell surface
messages: Endosome membrane
messages: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome
messages: Membrane
messages: extracellular exosome
messages: multivesicular body

9915:SEPT11
gene id: 9915:SEPT11
uniprot id: A0A6P5BYZ4
uniprot id: A0A6P5BYZ8
uniprot id: A0A6P5BZ03
uniprot id: A0A6P5BZC2
uniprot id: A0A6P5BZS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9915:LOC109571847
gene id: 9915:LOC109571847
uniprot id: A0A6P5D928
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109561048
gene id: 9915:LOC109561048
uniprot id: A0A6P5C1C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GJC3
gene id: 9915:GJC3
uniprot id: A0A6P5E018
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:LOC109577043
gene id: 9915:LOC109577043
uniprot id: A0A6P5DWM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9915:FAM65C
gene id: 9915:FAM65C
uniprot id: A0A6P5CPY5
names: Similarity
messages: Belongs to the RIPOR family.

9915:LOC109561737
gene id: 9915:LOC109561737
uniprot id: A0A6P5C345
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

9915:APOC4
gene id: 9915:APOC4
uniprot id: A0A6P5DDN8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein C4 family.
messages: May participate in lipoprotein metabolism.
messages: Secreted

9915:FAM102A
gene id: 9915:FAM102A
uniprot id: A0A6P5CLB5
names: Similarity
messages: Belongs to the FAM102 family.

9915:LOC109561677
gene id: 9915:LOC109561677
uniprot id: A0A6P5C2P3
uniprot id: A0A6P5C2U4
uniprot id: A0A6P5C2Z7
uniprot id: A0A6P5C403
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109558765
gene id: 9915:LOC109558765
uniprot id: A0A6P5BBM3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC37A1
gene id: 9915:SLC37A1
uniprot id: A0A6P5BZZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Inorganic phosphate and glucose-6-phosphate antiporter. May transport cytoplasmic glucose-6-phosphate into the lumen of the endoplasmic reticulum and translocate inorganic phosphate into the opposite direction. Independent of a lumenal glucose-6-phosphatase. May not play a role in homeostatic regulation of blood glucose levels.
messages: Membrane

9915:ANAPC5
gene id: 9915:ANAPC5
uniprot id: A0A6P5D4X7
uniprot id: A0A6P5D6A6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC5 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: spindle

9915:PPA1
gene id: 9915:PPA1
uniprot id: A0A6P5BAW2
names: Similarity
messages: Belongs to the PPase family.

9915:LOC109576898
gene id: 9915:LOC109576898
uniprot id: A0A6P5DS60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:SLC4A5
gene id: 9915:SLC4A5
uniprot id: A0A6P5CHK1
uniprot id: A0A6P5CIH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

9915:IK
gene id: 9915:IK
uniprot id: A0A6P5C4V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

9915:SESN1
gene id: 9915:SESN1
uniprot id: A0A6P5CBD1
uniprot id: A0A6P5CCG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9915:GALR2
gene id: 9915:GALR2
uniprot id: A0A6P5DF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:SLCO2B1
gene id: 9915:SLCO2B1
uniprot id: A0A6P5CZ34
uniprot id: A0A6P5D0L8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:GPR142
gene id: 9915:GPR142
uniprot id: A0A6P5DG12
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:RARS2
gene id: 9915:RARS2
uniprot id: A0A6P5CBQ8
uniprot id: A0A6P5CC58
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9915:MRPS2
gene id: 9915:MRPS2
uniprot id: A0A6P5CNB8
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

9915:SVOP
gene id: 9915:SVOP
uniprot id: A0A6P5D717
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

9915:APOD
gene id: 9915:APOD
uniprot id: A0A6P5BIA6
uniprot id: A0A6P5BPE0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Homodimer.
messages: Secreted

9915:SDHD
gene id: 9915:SDHD
uniprot id: A0A6P5B5U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

9915:BRK1
gene id: 9915:BRK1
uniprot id: A0A6P5DPL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRK1 family.
messages: cytoskeleton

9915:LSM8
gene id: 9915:LSM8
uniprot id: A0A6P5BLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

9915:LOC109576658
gene id: 9915:LOC109576658
uniprot id: A0A6P5DR59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NR2E1
gene id: 9915:NR2E1
uniprot id: A0A6P5CAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:MAS1
gene id: 9915:MAS1
uniprot id: A0A6P5CAF6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109573083
gene id: 9915:LOC109573083
uniprot id: A0A6P5DEK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:ARCN1
gene id: 9915:ARCN1
uniprot id: A0A6P5CYD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9915:LOC109553601
gene id: 9915:LOC109553601
uniprot id: A0A6P5AQZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pecanex family.
messages: Membrane

9915:LOC109569328
gene id: 9915:LOC109569328
uniprot id: A0A6P5CYK0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

9915:TAC3
gene id: 9915:TAC3
uniprot id: A0A6P5BBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tachykinin family.
messages: Secreted

9915:MAP3K21
gene id: 9915:MAP3K21
uniprot id: A0A6P5AYZ5
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

9915:UTS2
gene id: 9915:UTS2
uniprot id: A0A6P5D0Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

9915:FAM189A2
gene id: 9915:FAM189A2
uniprot id: A0A6P5C7H6
uniprot id: A0A6P5C8Y0
names: Similarity
messages: Belongs to the ENTREP family.

9915:FOXB2
gene id: 9915:FOXB2
uniprot id: A0A6P5C6N2
names: Subcellular Location Annotation
messages: Nucleus

9915:ADRA1B
gene id: 9915:ADRA1B
uniprot id: A0A6P5C5K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

9915:HOXB13
gene id: 9915:HOXB13
uniprot id: A0A6P5DEF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:STAT3
gene id: 9915:STAT3
uniprot id: A0A6P5DF35
uniprot id: A0A6P5DF36
uniprot id: A0A6P5DGP9
uniprot id: A0A6P5DI15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9915:ORMDL3
gene id: 9915:ORMDL3
uniprot id: A0A6P5DFG1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Interacts with SPTLC1.
messages: Membrane
messages: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.

9915:RUVBL1
gene id: 9915:RUVBL1
uniprot id: A0A6P5DRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9915:TCTEX1D1
gene id: 9915:TCTEX1D1
uniprot id: A0A6P5B7L1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:PLA2G10
gene id: 9915:PLA2G10
uniprot id: A0A6P5DYH0
uniprot id: A0A6P5DZ97
uniprot id: A0A6P5E1Y2
uniprot id: A0A6P5E2E6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9915:RPL29
gene id: 9915:RPL29
uniprot id: A0A6P5DNF2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

9915:SENP8
gene id: 9915:SENP8
uniprot id: A0A6P5CEC4
names: Similarity
messages: Belongs to the peptidase C48 family.

9915:LOC109574848
gene id: 9915:LOC109574848
uniprot id: A0A6P5DJR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:VAMP8
gene id: 9915:VAMP8
uniprot id: A0A6P5CKZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

9915:CRYBB2
gene id: 9915:CRYBB2
uniprot id: A0A6P5D5M8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

9915:BUD13
gene id: 9915:BUD13
uniprot id: A0A6P5CYF3
uniprot id: A0A6P5D109
names: Similarity
messages: Belongs to the CWC26 family.

9915:DNMT3A
gene id: 9915:DNMT3A
uniprot id: A0A6P5CLS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

9915:KCNU1
gene id: 9915:KCNU1
uniprot id: A0A6P5BHE2
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109574931
gene id: 9915:LOC109574931
uniprot id: A0A6P5DL37
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:BANP
gene id: 9915:BANP
uniprot id: A0A6P5DAE1
uniprot id: A0A6P5DAJ6
uniprot id: A0A6P5DAJ9
uniprot id: A0A6P5DCN1
uniprot id: A0A6P5DCN6
uniprot id: A0A6P5DCP8
uniprot id: A0A6P5DCQ3
names: Similarity
messages: Belongs to the BANP/SMAR1 family.

9915:PFDN6
gene id: 9915:PFDN6
uniprot id: A0A6P5DUX9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9915:LOC109568076
gene id: 9915:LOC109568076
uniprot id: A0A6P5CT55
uniprot id: A0A6P5CUK9
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:LOC109564338
gene id: 9915:LOC109564338
uniprot id: A0A6P5CD70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

9915:SMARCD2
gene id: 9915:SMARCD2
uniprot id: A0A6P5DG68
names: Similarity
messages: Belongs to the SMARCD family.

9915:PCK1
gene id: 9915:PCK1
uniprot id: A0A6P5CNN6
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

9915:RPL13A
gene id: 9915:RPL13A
uniprot id: A0A6P5DCI1
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9915:LOC109569383
gene id: 9915:LOC109569383
uniprot id: A0A6P5CYR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ENKUR
gene id: 9915:ENKUR
uniprot id: A0A6P5CRA0
names: Subcellular Location Annotation
messages: cilium axoneme

9915:PHB
gene id: 9915:PHB
uniprot id: A0A6P5DH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

9915:FZD9
gene id: 9915:FZD9
uniprot id: A0A6P5DWK4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:CCKAR
gene id: 9915:CCKAR
uniprot id: A0A6P5BWL4
uniprot id: A0A6P5BWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9915:LOC109571973
gene id: 9915:LOC109571973
uniprot id: A0A6P5D9E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9915:KXD1
gene id: 9915:KXD1
uniprot id: A0A6P5C1P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Lysosome membrane

9915:TBC1D23
gene id: 9915:TBC1D23
uniprot id: A0A6P5CIT2
uniprot id: A0A6P5CK66
names: Subcellular Location Annotation
messages: trans-Golgi network

9915:NOXRED1
gene id: 9915:NOXRED1
uniprot id: A0A6P5CIY0
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9915:TRIM2
gene id: 9915:TRIM2
uniprot id: A0A6P5D4G4
uniprot id: A0A6P5D566
uniprot id: A0A6P5D6B3
uniprot id: A0A6P5D7T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

9915:DUOXA1
gene id: 9915:DUOXA1
uniprot id: A0A6P5CF17
uniprot id: A0A6P5CHS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

9915:HOXB2
gene id: 9915:HOXB2
uniprot id: A0A6P5DFS5
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109568796
gene id: 9915:LOC109568796
uniprot id: A0A6P5CY24
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. NNMT/PNMT/TEMT family.

9915:DUS3L
gene id: 9915:DUS3L
uniprot id: A0A6P5C341
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

9915:AAR2
gene id: 9915:AAR2
uniprot id: A0A6P5CRQ7
names: Function
names: Similarity
messages: Belongs to the AAR2 family.
messages: Component of the U5 snRNP complex that is required for spliceosome assembly and for pre-mRNA splicing.

9915:CRMP1
gene id: 9915:CRMP1
uniprot id: A0A6P5BZA3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9915:GIPC1
gene id: 9915:GIPC1
uniprot id: A0A6P5C1S8
names: Similarity
messages: Belongs to the GIPC family.

9915:PGAM2
gene id: 9915:PGAM2
uniprot id: A0A6P5DSZ7
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9915:LHX8
gene id: 9915:LHX8
uniprot id: A0A6P5BQB4
names: Subcellular Location Annotation
messages: Nucleus

9915:PGLYRP4
gene id: 9915:PGLYRP4
uniprot id: A0A6P5BJI6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9915:KLHL40
gene id: 9915:KLHL40
uniprot id: A0A6P5DS49
names: Similarity
names: Subcellular Location Annotation
messages: A band
messages: Belongs to the KLHL40 family.
messages: I band

9915:GRIA2
gene id: 9915:GRIA2
uniprot id: A0A6P5D7D5
uniprot id: A0A6P5D8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:PLXNB1
gene id: 9915:PLXNB1
uniprot id: A0A6P5DQ50
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:ITPK1
gene id: 9915:ITPK1
uniprot id: A0A6P5DND2
names: Similarity
messages: Belongs to the ITPK1 family.

9915:ZBTB8OS
gene id: 9915:ZBTB8OS
uniprot id: A0A6P5DA52
uniprot id: A0A6P5DBZ1
names: Similarity
names: Subunit
messages: Belongs to the archease family.
messages: Component of the tRNA-splicing ligase complex.

9915:TPP1
gene id: 9915:TPP1
uniprot id: A0A6P5CZJ8
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

9915:PLCZ1
gene id: 9915:PLCZ1
uniprot id: A0A6P5BER0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
messages: perinuclear region

9915:NT5DC4
gene id: 9915:NT5DC4
uniprot id: A0A6P5CH73
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

9915:TBX5
gene id: 9915:TBX5
uniprot id: A0A6P5D4B2
uniprot id: A0A6P5D5D7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:LOC109569004
gene id: 9915:LOC109569004
uniprot id: A0A6P5CV38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109559715
gene id: 9915:LOC109559715
uniprot id: A0A6P5BVC7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109565612
gene id: 9915:LOC109565612
uniprot id: A0A6P5CI06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9915:SKA3
gene id: 9915:SKA3
uniprot id: A0A6P5CNK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

9915:FXYD5
gene id: 9915:FXYD5
uniprot id: A0A6P5D8V0
uniprot id: A0A6P5DCC0
names: Similarity
messages: Belongs to the FXYD family.

9915:NLK
gene id: 9915:NLK
uniprot id: A0A6P5DGM1
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

9915:DYNLT1
gene id: 9915:DYNLT1
uniprot id: A0A6P5CDP2
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:TAF10
gene id: 9915:TAF10
uniprot id: A0A6P5CVX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Nucleus
messages: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription.

9915:SFN
gene id: 9915:SFN
uniprot id: A0A6P5DCR4
names: Similarity
messages: Belongs to the 14-3-3 family.

9915:CSF3
gene id: 9915:CSF3
uniprot id: A0A6P5DD71
uniprot id: A0A6P5DF10
uniprot id: A0A6P5DFK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
messages: Secreted

9915:SLC23A2
gene id: 9915:SLC23A2
uniprot id: A0A6P5CTB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

9915:SLC25A45
gene id: 9915:SLC25A45
uniprot id: A0A6P5BE40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:LOC109554064
gene id: 9915:LOC109554064
uniprot id: A0A6P5AZK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MYSM1
gene id: 9915:MYSM1
uniprot id: A0A6P5B309
uniprot id: A0A6P5BHW0
names: Similarity
messages: Belongs to the peptidase M67A family. MYSM1 subfamily.

9915:DYNC1LI2
gene id: 9915:DYNC1LI2
uniprot id: A0A6P5D9L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

9915:ISOC2
gene id: 9915:ISOC2
uniprot id: A0A6P5DBI7
uniprot id: A0A6P5DEP6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isochorismatase family.
messages: Cytoplasm
messages: Interacts with CDKN2A.
messages: Nucleus

9915:C14H8orf82
gene id: 9915:C14H8orf82
uniprot id: A0A6P5CUF0
names: Similarity
messages: Belongs to the UPF0598 family.

9915:HOMER2
gene id: 9915:HOMER2
uniprot id: A0A6P5DQ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9915:LOC109569332
gene id: 9915:LOC109569332
uniprot id: A0A6P5CWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109557884
gene id: 9915:LOC109557884
uniprot id: A0A6P5B9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

9915:UCHL5
gene id: 9915:UCHL5
uniprot id: A0A6P5D0Q4
uniprot id: A0A6P5D1T9
names: Similarity
messages: Belongs to the peptidase C12 family.

9915:CFAP43
gene id: 9915:CFAP43
uniprot id: A0A6P5APK1
uniprot id: A0A6P5B861
uniprot id: A0A6P5BGS9
uniprot id: A0A6P5BH88
names: Similarity
messages: Belongs to the CFAP43 family.

9915:PSMB6
gene id: 9915:PSMB6
uniprot id: A0A6P5DKZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9915:RNASEH2A
gene id: 9915:RNASEH2A
uniprot id: A0A6P5C1W7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

9915:DDR1
gene id: 9915:DDR1
uniprot id: A0A6P5DT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

9915:GPX4
gene id: 9915:GPX4
uniprot id: A0A6P5C4M9
uniprot id: A0A6P5C5M1
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:TGFB1
gene id: 9915:TGFB1
uniprot id: A0A6P5DB61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Required to maintain the Transforming growth factor beta-1 (TGF-beta-1) chain in a latent state during storage in extracellular matrix. Associates non-covalently with TGF-beta-1 and regulates its activation via interaction with 'milieu molecules', such as LTBP1, LRRC32/GARP and LRRC33/NRROS, that control activation of TGF-beta-1. Interaction with LRRC33/NRROS regulates activation of TGF-beta-1 in macrophages and microglia. Interaction with LRRC32/GARP controls activation of TGF-beta-1 on the surface of activated regulatory T-cells (Tregs). Interaction with integrins (ITGAV:ITGB6 or ITGAV:ITGB8) results in distortion of the Latency-associated peptide chain and subsequent release of the active TGF-beta-1.
messages: Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1, respectively.
messages: extracellular matrix

9915:FAM26D
gene id: 9915:FAM26D
uniprot id: A0A6P5CAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9915:LOC109554639
gene id: 9915:LOC109554639
uniprot id: A0A6P5BKT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex).
messages: Belongs to the UQCC3 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays an important role in ATP production by mitochondria. Cardiolipin-binding protein, it may also control the cardiolipin composition of mitochondria membranes and their morphology.

9915:LOC109576633
gene id: 9915:LOC109576633
uniprot id: A0A6P5DV24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109564499
gene id: 9915:LOC109564499
uniprot id: A0A6P5CDY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SHOC2
gene id: 9915:SHOC2
uniprot id: A0A6P5E060
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

9915:TMBIM1
gene id: 9915:TMBIM1
uniprot id: A0A6P5D1G9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9915:CHD7
gene id: 9915:CHD7
uniprot id: A0A6P5CUX5
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

9915:LOC109557960
gene id: 9915:LOC109557960
uniprot id: A0A6P5BLC3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576538
gene id: 9915:LOC109576538
uniprot id: A0A6P5DS78
names: Subcellular Location Annotation
messages: cytoskeleton

9915:VPS52
gene id: 9915:VPS52
uniprot id: A0A6P5DSC3
uniprot id: A0A6P5DUV9
names: Similarity
messages: Belongs to the VPS52 family.

9915:NQO1
gene id: 9915:NQO1
uniprot id: A0A6P5DDB8
names: Similarity
messages: Belongs to the NAD(P)H dehydrogenase (quinone) family.

9915:LOC109569291
gene id: 9915:LOC109569291
uniprot id: A0A6P5CYG7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KCNJ16
gene id: 9915:KCNJ16
uniprot id: A0A6P5DKB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9915:SGCG
gene id: 9915:SGCG
uniprot id: A0A6P5CQB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

9915:PAXBP1
gene id: 9915:PAXBP1
uniprot id: A0A6P5C4J8
names: Similarity
messages: Belongs to the GCF family.

9915:ADI1
gene id: 9915:ADI1
uniprot id: A0A6P5CAH1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. Also down-regulates cell migration mediated by MMP14.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer. Interacts with MMP14.
messages: Nucleus

9915:LOC109561475
gene id: 9915:LOC109561475
uniprot id: A0A6P5C201
uniprot id: A0A6P5C214
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:AUH
gene id: 9915:AUH
uniprot id: A0A6P5C6T2
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9915:GATM
gene id: 9915:GATM
uniprot id: A0A6P5CG98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

9915:NDUFS5
gene id: 9915:NDUFS5
uniprot id: A0A6P5B4C1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS5 subunit family.
messages: Mammalian complex I is composed of 45 different subunits. This is a component of the iron-sulfur (IP) fragment of the enzyme.
messages: Membrane
messages: Mitochondrion inner membrane

9915:LOC109575887
gene id: 9915:LOC109575887
uniprot id: A0A6P5DRB8
names: Similarity
messages: Belongs to the cAMP-dependent kinase regulatory chain family.

9915:PDE1C
gene id: 9915:PDE1C
uniprot id: A0A6P5B7E0
uniprot id: A0A6P5B7E4
uniprot id: A0A6P5BBS7
uniprot id: A0A6P5BK70
uniprot id: A0A6P5BQR5
uniprot id: A0A6P5BQR6
uniprot id: A0A6P5BQR7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:AGBL4
gene id: 9915:AGBL4
uniprot id: A0A6P5BA97
names: Similarity
messages: Belongs to the peptidase M14 family.

9915:ENPP1
gene id: 9915:ENPP1
uniprot id: A0A6P5C9R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.
messages: Secreted

9915:FAM124A
gene id: 9915:FAM124A
uniprot id: A0A6P5CPW6
names: Similarity
messages: Belongs to the FAM124 family.

9915:SLC25A15
gene id: 9915:SLC25A15
uniprot id: A0A6P5CN69
uniprot id: A0A6P5CPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:NETO1
gene id: 9915:NETO1
uniprot id: A0A6P5DX41
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:OXTR
gene id: 9915:OXTR
uniprot id: A0A6P5DQ18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.

9915:RAB3C
gene id: 9915:RAB3C
uniprot id: A0A6P5DKB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

9915:SPTBN2
gene id: 9915:SPTBN2
uniprot id: A0A6P5BJ61
names: Similarity
messages: Belongs to the spectrin family.

9915:LOC109560852
gene id: 9915:LOC109560852
uniprot id: A0A6P5BZZ7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:THNSL2
gene id: 9915:THNSL2
uniprot id: A0A6P5CJJ6
names: Similarity
messages: Belongs to the threonine synthase family.

9915:DGAT2
gene id: 9915:DGAT2
uniprot id: A0A6P5D0R2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:WASF3
gene id: 9915:WASF3
uniprot id: A0A6P5CQ97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9915:SVBP
gene id: 9915:SVBP
uniprot id: A0A6P5BPG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVBP family.
messages: Secreted
messages: cytoskeleton

9915:LDB2
gene id: 9915:LDB2
uniprot id: A0A6P5BZE5
uniprot id: A0A6P5BZE7
uniprot id: A0A6P5BZG3
uniprot id: A0A6P5BZR9
names: Similarity
messages: Belongs to the LDB family.

9915:TNFRSF6B
gene id: 9915:TNFRSF6B
uniprot id: A0A6P5CQS0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MAP3K6
gene id: 9915:MAP3K6
uniprot id: A0A6P5DE70
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9915:KIF9
gene id: 9915:KIF9
uniprot id: A0A6P5DQ14
uniprot id: A0A6P5DRJ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109553335
gene id: 9915:LOC109553335
uniprot id: A0A6P5AQ58
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109565632
gene id: 9915:LOC109565632
uniprot id: A0A6P5CIB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PTPRCAP
gene id: 9915:PTPRCAP
uniprot id: A0A6P5BCJ6
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CD45/PTPRC.
messages: Membrane

9915:LOC109558573
gene id: 9915:LOC109558573
uniprot id: A0A6P5BM31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cytoplasm

9915:ACSS2
gene id: 9915:ACSS2
uniprot id: A0A6P5CQT2
uniprot id: A0A6P5CSN3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:HGFAC
gene id: 9915:HGFAC
uniprot id: A0A6P5BWK5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109556190
gene id: 9915:LOC109556190
uniprot id: A0A6P5BP36
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

9915:LOC109574525
gene id: 9915:LOC109574525
uniprot id: A0A6P5DIV7
uniprot id: A0A6P5DM41
names: Similarity
messages: Belongs to the intermediate filament family.

9915:TSR2
gene id: 9915:TSR2
uniprot id: A0A6P5AW50
names: Function
names: Similarity
messages: Belongs to the TSR2 family.
messages: May be involved in 20S pre-rRNA processing.

9915:ELAVL4
gene id: 9915:ELAVL4
uniprot id: A0A6P5B695
uniprot id: A0A6P5BAQ6
uniprot id: A0A6P5BAQ9
uniprot id: A0A6P5BJL3
uniprot id: A0A6P5BQ89
uniprot id: A0A6P5BQ91
uniprot id: A0A6P5BQC0
uniprot id: A0A6P5BQC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

9915:TFIP11
gene id: 9915:TFIP11
uniprot id: A0A6P5D516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFP11/STIP family.
messages: Identified in the spliceosome C complex. Found in the Intron Large (IL) complex, a post-mRNA release spliceosomal complex containing the excised intron, U2, U5 and U6 snRNPs, and splicing factors. Interacts with TUFT1. Interacts with DHX15; indicative for a recruitment of DHX15 to the IL complex. Interacts with GCFC2.
messages: Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix.
messages: Nucleus

9915:LOC109561004
gene id: 9915:LOC109561004
uniprot id: A0A6P5C077
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568087
gene id: 9915:LOC109568087
uniprot id: A0A6P5CS79
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:CACNA2D2
gene id: 9915:CACNA2D2
uniprot id: A0A6P5DP80
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9915:LOC109557098
gene id: 9915:LOC109557098
uniprot id: A0A6P5BQA9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558146
gene id: 9915:LOC109558146
uniprot id: A0A6P5BLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568255
gene id: 9915:LOC109568255
uniprot id: A0A6P5CV00
names: Subcellular Location Annotation
messages: Nucleus

9915:ITGA1
gene id: 9915:ITGA1
uniprot id: A0A6P5DML7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:LOC109560930
gene id: 9915:LOC109560930
uniprot id: A0A6P5C030
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DYSF
gene id: 9915:DYSF
uniprot id: A0A6P5CJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferlin family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9915:MXRA8
gene id: 9915:MXRA8
uniprot id: A0A6P5D1J7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:HPS3
gene id: 9915:HPS3
uniprot id: A0A6P5BTV0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: Cytoplasm
messages: Involved in early stages of melanosome biogenesis and maturation.

9915:TBC1D24
gene id: 9915:TBC1D24
uniprot id: A0A6P5DYS6
uniprot id: A0A6P5DYX2
uniprot id: A0A6P5DZL7
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

9915:LMOD3
gene id: 9915:LMOD3
uniprot id: A0A6P5DNT4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

9915:DZIP1L
gene id: 9915:DZIP1L
uniprot id: A0A6P5BWD3
uniprot id: A0A6P5BWE9
uniprot id: A0A6P5BWP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DZIP C2H2-type zinc-finger protein family.
messages: centriole
messages: cilium basal body

9915:SLC1A7
gene id: 9915:SLC1A7
uniprot id: A0A6P5B7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9915:PEBP1
gene id: 9915:PEBP1
uniprot id: A0A6P5D753
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

9915:LTB4R2
gene id: 9915:LTB4R2
uniprot id: A0A6P5CDP6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:SH3GL1
gene id: 9915:SH3GL1
uniprot id: A0A6P5C302
uniprot id: A0A6P5C3A4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Implicated in endocytosis. May recruit other proteins to membranes with high curvature.
messages: Membrane

9915:PSMD1
gene id: 9915:PSMD1
uniprot id: A0A6P5D718
uniprot id: A0A6P5DAL0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

9915:PTGFR
gene id: 9915:PTGFR
uniprot id: A0A6P5BHM7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109569558
gene id: 9915:LOC109569558
uniprot id: A0A6P5CX74
names: Similarity
messages: Belongs to the histone H2B family.

9915:ABT1
gene id: 9915:ABT1
uniprot id: A0A6P5DTH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

9915:CDK3
gene id: 9915:CDK3
uniprot id: A0A6P5DE44
uniprot id: A0A6P5DFU4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:F2RL2
gene id: 9915:F2RL2
uniprot id: A0A6P5CCT8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:P4HA1
gene id: 9915:P4HA1
uniprot id: A0A6P5BHQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9915:LOC109574301
gene id: 9915:LOC109574301
uniprot id: A0A6P5DL31
names: Similarity
messages: Belongs to the intermediate filament family.

9915:LOC109563785
gene id: 9915:LOC109563785
uniprot id: A0A6P5CAT5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:GUF1
gene id: 9915:GUF1
uniprot id: A0A6P5BY46
uniprot id: A0A6P5BY47
uniprot id: A0A6P5BYJ8
uniprot id: A0A6P5BYY8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

9915:CPPED1
gene id: 9915:CPPED1
uniprot id: A0A6P5DZX3
names: Function
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. CPPED1 family.
messages: Protein phosphatase that dephosphorylates AKT family kinase specifically at 'Ser-473', blocking cell cycle progression and promoting cell apoptosis. May play an inhibitory role in glucose uptake by adipocytes.

9915:LOC109556981
gene id: 9915:LOC109556981
uniprot id: A0A6P5BQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HDC
gene id: 9915:HDC
uniprot id: A0A6P5CFG7
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9915:DPYSL5
gene id: 9915:DPYSL5
uniprot id: A0A6P5CJ87
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

9915:GGA1
gene id: 9915:GGA1
uniprot id: A0A6P5BVP8
uniprot id: A0A6P5BVR0
uniprot id: A0A6P5BVR6
uniprot id: A0A6P5BW11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

9915:TCHHL1
gene id: 9915:TCHHL1
uniprot id: A0A6P5AW37
names: Similarity
messages: Belongs to the S-100 family.

9915:ADGRB2
gene id: 9915:ADGRB2
uniprot id: A0A6P5DNE3
names: Subcellular Location Annotation
messages: Membrane

9915:HOXA6
gene id: 9915:HOXA6
uniprot id: A0A6P5BK99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:ACSM1
gene id: 9915:ACSM1
uniprot id: A0A6P5DZ14
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:HPD
gene id: 9915:HPD
uniprot id: A0A6P5D5Q3
uniprot id: A0A6P5D6U1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

9915:CD93
gene id: 9915:CD93
uniprot id: A0A6P5CTC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109561950
gene id: 9915:LOC109561950
uniprot id: A0A6P5C451
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase VIIb family.
messages: Membrane
messages: Mitochondrion inner membrane

9915:ZFHX2
gene id: 9915:ZFHX2
uniprot id: A0A6P5CDV4
uniprot id: A0A6P5CF05
names: Subcellular Location Annotation
messages: Nucleus

9915:LPL
gene id: 9915:LPL
uniprot id: A0A6P5C8L4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Cell membrane
messages: Homodimer. Interacts with APOC2; the interaction activates LPL activity in the presence of lipids.
messages: Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Tyrosine nitration after lipopolysaccharide (LPS) challenge down-regulates the lipase activity.
messages: extracellular matrix

9915:MRPS11
gene id: 9915:MRPS11
uniprot id: A0A6P5DQA9
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

9915:MSRB2
gene id: 9915:MSRB2
uniprot id: A0A6P5CSR6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

9915:DCAF11
gene id: 9915:DCAF11
uniprot id: A0A6P5CDT3
uniprot id: A0A6P5CEL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat LEC14B family.
messages: Interacts with DDB1 and CUL4A.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

9915:LOC109560882
gene id: 9915:LOC109560882
uniprot id: A0A6P5C090
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EMX2
gene id: 9915:EMX2
uniprot id: A0A6P5B7T8
names: Subcellular Location Annotation
messages: Nucleus

9915:EVX2
gene id: 9915:EVX2
uniprot id: A0A6P5DKT5
names: Subcellular Location Annotation
messages: Nucleus

9915:SNX33
gene id: 9915:SNX33
uniprot id: A0A6P5DPY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9915:TERT
gene id: 9915:TERT
uniprot id: A0A6P5DNU1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nucleotide telomeric repeat unit, 5'-TTAGGG-3'. The catalytic cycle involves primer binding, primer extension and release of product once the template boundary has been reached or nascent product translocation followed by further extension. More active on substrates containing 2 or 3 telomeric repeats. Telomerase activity is regulated by a number of factors including telomerase complex-associated proteins, chaperones and polypeptide modifiers. Modulates Wnt signaling. Plays important roles in aging and antiapoptosis.
messages: The RNA-interacting domain 1 (RD1)/N-terminal extension (NTE) is required for interaction with the pseudoknot-template domain of each of TERC dimers. It contains anchor sites that bind primer nucleotides upstream of the RNA-DNA hybrid and is thus an essential determinant of repeat addition processivity.
messages: The RNA-interacting domain 2 (RD2) is essential for both interaction with the CR4-CR5 domain of TERC and for DNA synthesis.
messages: The primer grip sequence in the RT domain is required for telomerase activity and for stable association with short telomeric primers.
messages: nucleolus
messages: nucleoplasm
messages: telomere

9915:EGF
gene id: 9915:EGF
uniprot id: A0A6P5BWE1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TGM3
gene id: 9915:TGM3
uniprot id: A0A6P5CRP6
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9915:MAOA
gene id: 9915:MAOA
uniprot id: A0A6P5B3Y7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the flavin monoamine oxidase family.
messages: Mitochondrion outer membrane
messages: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer.

9915:GPR20
gene id: 9915:GPR20
uniprot id: A0A6P5CSM1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109561709
gene id: 9915:LOC109561709
uniprot id: A0A6P5C2S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane

9915:CELF2
gene id: 9915:CELF2
uniprot id: A0A6P5CQY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9915:LOC109576970
gene id: 9915:LOC109576970
uniprot id: A0A6P5DSC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PLD3
gene id: 9915:PLD3
uniprot id: A0A6P5D6J2
names: Similarity
messages: Belongs to the phospholipase D family.

9915:SNRPE
gene id: 9915:SNRPE
uniprot id: A0A6P5D649
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing.
messages: cytosol

9915:PPP4C
gene id: 9915:PPP4C
uniprot id: A0A6P5DZU3
names: Similarity
messages: Belongs to the PPP phosphatase family.

9915:PPP1R3B
gene id: 9915:PPP1R3B
uniprot id: A0A6P5AQQ9
uniprot id: A0A6P5BHX2
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

9915:LDB1
gene id: 9915:LDB1
uniprot id: A0A6P5E084
uniprot id: A0A6P5E0G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDB family.
messages: Nucleus

9915:STEAP2
gene id: 9915:STEAP2
uniprot id: A0A6P5BQW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

9915:LOC109573396
gene id: 9915:LOC109573396
uniprot id: A0A6P5DG71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109577340
gene id: 9915:LOC109577340
uniprot id: A0A6P5DTT6
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

9915:SSBP1
gene id: 9915:SSBP1
uniprot id: A0A6P5BCN8
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9915:HYI
gene id: 9915:HYI
uniprot id: A0A6P5BPE8
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

9915:LOC109566869
gene id: 9915:LOC109566869
uniprot id: A0A6P5CN52
names: Similarity
messages: Belongs to the histone H2B family.

9915:RPL10L
gene id: 9915:RPL10L
uniprot id: A0A6P5CCJ2
uniprot id: A0A6P5CET2
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9915:LOC109554049
gene id: 9915:LOC109554049
uniprot id: A0A6P5BBD3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GJD2
gene id: 9915:GJD2
uniprot id: A0A6P5CDL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:CDCP2
gene id: 9915:CDCP2
uniprot id: A0A6P5B5Q7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109558486
gene id: 9915:LOC109558486
uniprot id: A0A6P5BRY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ANXA13
gene id: 9915:ANXA13
uniprot id: A0A6P5CUD7
uniprot id: A0A6P5CVC2
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9915:TNFAIP1
gene id: 9915:TNFAIP1
uniprot id: A0A6P5DE58
names: Similarity
messages: Belongs to the BACURD family.

9915:GABRQ
gene id: 9915:GABRQ
uniprot id: A0A6P5B2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:PHAX
gene id: 9915:PHAX
uniprot id: A0A6P5C057
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

9915:SH3BGRL
gene id: 9915:SH3BGRL
uniprot id: A0A6P5BMC0
names: Similarity
messages: Belongs to the SH3BGR family.

9915:LOC109569117
gene id: 9915:LOC109569117
uniprot id: A0A6P5CXW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:AES
gene id: 9915:AES
uniprot id: A0A6P5C4I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

9915:RNASE4
gene id: 9915:RNASE4
uniprot id: A0A6P5CFA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:GOSR1
gene id: 9915:GOSR1
uniprot id: A0A6P5DG74
uniprot id: A0A6P5DHR8
uniprot id: A0A6P5DIL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

9915:RNF175
gene id: 9915:RNF175
uniprot id: A0A6P5D510
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569096
gene id: 9915:LOC109569096
uniprot id: A0A6P5CVA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576635
gene id: 9915:LOC109576635
uniprot id: A0A6P5DSJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:ACKR3
gene id: 9915:ACKR3
uniprot id: A0A6P5B4U9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:DMBX1
gene id: 9915:DMBX1
uniprot id: A0A6P5BAR9
uniprot id: A0A6P5BQA8
names: Subcellular Location Annotation
messages: Nucleus

9915:FAM151A
gene id: 9915:FAM151A
uniprot id: A0A6P5B328
names: Similarity
messages: Belongs to the FAM151 family.

9915:CHURC1
gene id: 9915:CHURC1
uniprot id: A0A6P5CFZ8
uniprot id: A0A6P5CGP1
uniprot id: A0A6P5CH12
uniprot id: A0A6P5CI85
names: Similarity
messages: Belongs to the Churchill family.

9915:LOC109577387
gene id: 9915:LOC109577387
uniprot id: A0A6P5DV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:EGR3
gene id: 9915:EGR3
uniprot id: A0A6P5C8J2
uniprot id: A0A6P5C8R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

9915:RUNX1T1
gene id: 9915:RUNX1T1
uniprot id: A0A6P5CUJ1
uniprot id: A0A6P5CW13
names: Similarity
messages: Belongs to the CBFA2T family.

9915:SPARCL1
gene id: 9915:SPARCL1
uniprot id: A0A6P5BZ99
names: Similarity
messages: Belongs to the SPARC family.

9915:TUBGCP4
gene id: 9915:TUBGCP4
uniprot id: A0A6P5DLJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

9915:FOXN1
gene id: 9915:FOXN1
uniprot id: A0A6P5DDI0
names: Subcellular Location Annotation
messages: Nucleus

9915:PIK3R2
gene id: 9915:PIK3R2
uniprot id: A0A6P5C1S5
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

9915:RPS6KB1
gene id: 9915:RPS6KB1
uniprot id: A0A6P5DGZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
messages: Cytoplasm

9915:FAM216A
gene id: 9915:FAM216A
uniprot id: A0A6P5D544
uniprot id: A0A6P5D8Y7
names: Similarity
messages: Belongs to the FAM216 family.

9915:ENGASE
gene id: 9915:ENGASE
uniprot id: A0A6P5DHC3
uniprot id: A0A6P5DJS4
uniprot id: A0A6P5DKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

9915:PIP
gene id: 9915:PIP
uniprot id: A0A6P5BCQ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PIP family.
messages: Monomer. Interacts with AZGP1.
messages: Secreted

9915:PTPRN2
gene id: 9915:PTPRN2
uniprot id: A0A6P5B9S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

9915:LOC109575761
gene id: 9915:LOC109575761
uniprot id: A0A6P5DR43
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109576111
gene id: 9915:LOC109576111
uniprot id: A0A6P5DSU9
names: Similarity
messages: Belongs to the CAND family.

9915:MTX3
gene id: 9915:MTX3
uniprot id: A0A6P5CD91
uniprot id: A0A6P5CE05
uniprot id: A0A6P5CEF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9915:ACOD1
gene id: 9915:ACOD1
uniprot id: A0A6P5CM04
names: Similarity
messages: Belongs to the PrpD family.

9915:SYN3
gene id: 9915:SYN3
uniprot id: A0A6P5BUA0
uniprot id: A0A6P5BUB0
names: Similarity
messages: Belongs to the synapsin family.

9915:RPA3
gene id: 9915:RPA3
uniprot id: A0A6P5BAF9
uniprot id: A0A6P5BLR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

9915:HOXA11
gene id: 9915:HOXA11
uniprot id: A0A6P5B7J5
uniprot id: A0A6P5BQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:STRIP1
gene id: 9915:STRIP1
uniprot id: A0A6P5BH49
names: Similarity
messages: Belongs to the STRIP family.

9915:RPA1
gene id: 9915:RPA1
uniprot id: A0A6P5DGI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

9915:MS4A15
gene id: 9915:MS4A15
uniprot id: A0A6P5B010
uniprot id: A0A6P5BJC5
names: Similarity
messages: Belongs to the MS4A family.

9915:AHSA2
gene id: 9915:AHSA2
uniprot id: A0A6P5CIS3
uniprot id: A0A6P5CJU5
uniprot id: A0A6P5CK95
uniprot id: A0A6P5CLZ7
names: Similarity
messages: Belongs to the AHA1 family.

9915:CDX4
gene id: 9915:CDX4
uniprot id: A0A6P5BEV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9915:LOC109556760
gene id: 9915:LOC109556760
uniprot id: A0A6P5BJ93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NOL6
gene id: 9915:NOL6
uniprot id: A0A6P5C923
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

9915:AFF4
gene id: 9915:AFF4
uniprot id: A0A6P5C4T5
uniprot id: A0A6P5C5S5
names: Similarity
messages: Belongs to the AF4 family.

9915:RAD23B
gene id: 9915:RAD23B
uniprot id: A0A6P5C970
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

9915:WNT2
gene id: 9915:WNT2
uniprot id: A0A6P5BK19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:SLC6A18
gene id: 9915:SLC6A18
uniprot id: A0A6P5DKB9
names: Subcellular Location Annotation
messages: Membrane

9915:SLC16A9
gene id: 9915:SLC16A9
uniprot id: A0A6P5ASK3
uniprot id: A0A6P5BIY8
names: Subcellular Location Annotation
messages: Membrane

9915:MBOAT2
gene id: 9915:MBOAT2
uniprot id: A0A6P5CLC3
uniprot id: A0A6P5CM41
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109560929
gene id: 9915:LOC109560929
uniprot id: A0A6P5C0C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109573624
gene id: 9915:LOC109573624
uniprot id: A0A6P5DE03
uniprot id: A0A6P5DH35
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9915:CALR3
gene id: 9915:CALR3
uniprot id: A0A6P5C0K6
uniprot id: A0A6P5C0V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calreticulin family.
messages: Endoplasmic reticulum lumen

9915:NUMBL
gene id: 9915:NUMBL
uniprot id: A0A6P5DCW8
uniprot id: A0A6P5DCZ1
names: Function
messages: Plays a role in the process of neurogenesis.

9915:FAM131B
gene id: 9915:FAM131B
uniprot id: A0A6P5BKX1
names: Similarity
messages: Belongs to the FAM131 family.

9915:HSF4
gene id: 9915:HSF4
uniprot id: A0A6P5D8L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:LOC109570540
gene id: 9915:LOC109570540
uniprot id: A0A6P5D5A5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PIAS1
gene id: 9915:PIAS1
uniprot id: A0A6P5CDG7
names: Similarity
messages: Belongs to the PIAS family.

9915:LOC109578962
gene id: 9915:LOC109578962
uniprot id: A0A6P5E0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GPD1
gene id: 9915:GPD1
uniprot id: A0A6P5BSV2
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

9915:CCS
gene id: 9915:CCS
uniprot id: A0A6P5BDH2
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the Cu-Zn superoxide dismutase family.
messages: Nucleus

9915:LOC109564486
gene id: 9915:LOC109564486
uniprot id: A0A6P5CDW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:WIF1
gene id: 9915:WIF1
uniprot id: A0A6P5BT88
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ABCD1
gene id: 9915:ABCD1
uniprot id: A0A6P5AY80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

9915:ZP3
gene id: 9915:ZP3
uniprot id: A0A6P5DWX0
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

9915:LDB3
gene id: 9915:LDB3
uniprot id: A0A6P5AXR1
names: Subcellular Location Annotation
messages: Z line

9915:SEH1L
gene id: 9915:SEH1L
uniprot id: A0A6P5DZ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore.
messages: Lysosome membrane
messages: kinetochore

9915:RHBDL1
gene id: 9915:RHBDL1
uniprot id: A0A6P5DX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Membrane

9915:GMDS
gene id: 9915:GMDS
uniprot id: A0A6P5DVB4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

9915:LOC109562126
gene id: 9915:LOC109562126
uniprot id: A0A6P5C596
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:LOC109571278
gene id: 9915:LOC109571278
uniprot id: A0A6P5D525
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9915:SATB2
gene id: 9915:SATB2
uniprot id: A0A6P5CZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9915:LOC109573036
gene id: 9915:LOC109573036
uniprot id: A0A6P5DBZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Membrane
messages: Microsome membrane

9915:LOC109565800
gene id: 9915:LOC109565800
uniprot id: A0A6P5CIK6
uniprot id: A0A6P5CJ33
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

9915:CPSF3
gene id: 9915:CPSF3
uniprot id: A0A6P5CKU6
names: Subcellular Location Annotation
messages: Nucleus

9915:PDK1
gene id: 9915:PDK1
uniprot id: A0A6P5CMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

9915:PTTG1
gene id: 9915:PTTG1
uniprot id: A0A6P5C5L7
uniprot id: A0A6P5C5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

9915:SKP1
gene id: 9915:SKP1
uniprot id: A0A6P5C4U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of multiple SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complexes formed of CUL1, SKP1, RBX1 and a variable F-box domain-containing protein as substrate-specific subunit.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.
messages: The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component.

9915:STK4
gene id: 9915:STK4
uniprot id: A0A6P5CPL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Nucleus

9915:CD5L
gene id: 9915:CD5L
uniprot id: A0A6P5B5G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109559502
gene id: 9915:LOC109559502
uniprot id: A0A6P5BUE8
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:SLC9C1
gene id: 9915:SLC9C1
uniprot id: A0A6P5DB00
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

9915:GLYATL2
gene id: 9915:GLYATL2
uniprot id: A0A6P5CWI2
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9915:MAT2A
gene id: 9915:MAT2A
uniprot id: A0A6P5CK71
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9915:SCGN
gene id: 9915:SCGN
uniprot id: A0A6P5DX05
names: Subcellular Location Annotation
messages: secretory vesicle membrane

9915:C5H12orf75
gene id: 9915:C5H12orf75
uniprot id: A0A6P5BAZ9
names: Similarity
messages: Belongs to the OCC1 family.

9915:ATP2A2
gene id: 9915:ATP2A2
uniprot id: A0A6P5D372
uniprot id: A0A6P5D4C7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9915:KEG07 p11
gene id: 9915:KEG07_p11
uniprot id: E7BTI1
uniprot id: Q6EMS9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 2 heme A groups non-covalently per subunit.
messages: Binds a copper B center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). As a newly synthesized protein, rapidly incorporates into a multi-subunit assembly intermediate in the inner membrane, called MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase) complex, whose core components are COA3/MITRAC12 and COX14. Within the MITRAC complex, interacts with COA3 and with SMIM20/MITRAC7; the interaction with SMIM20 stabilizes the newly synthesized MT-CO1 and prevents its premature turnover. Interacts with TMEM177 in a COX20-dependent manner (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9915:TMEM159
gene id: 9915:TMEM159
uniprot id: A0A6P5DZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

9915:PBRM1
gene id: 9915:PBRM1
uniprot id: A0A6P5DRY5
names: Subcellular Location Annotation
messages: Nucleus

9915:VDAC3
gene id: 9915:VDAC3
uniprot id: A0A6P5BH70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.
messages: Interacts with ARMC12 in a TBC1D21-dependent manner.
messages: Mitochondrion outer membrane

9915:TACC2
gene id: 9915:TACC2
uniprot id: A0A6P5E099
uniprot id: A0A6P5E0B1
uniprot id: A0A6P5E0C1
uniprot id: A0A6P5E0H2
uniprot id: A0A6P5E0I0
uniprot id: A0A6P5E0J2
uniprot id: A0A6P5E143
uniprot id: A0A6P5E150
uniprot id: A0A6P5E3K1
uniprot id: A0A6P5E3K9
uniprot id: A0A6P5E405
uniprot id: A0A6P5E412
uniprot id: A0A6P5E421
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9915:MRPS10
gene id: 9915:MRPS10
uniprot id: A0A6P5DT64
uniprot id: A0A6P5DXD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

9915:LOC109564489
gene id: 9915:LOC109564489
uniprot id: A0A6P5CCE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TAGLN2
gene id: 9915:TAGLN2
uniprot id: A0A6P5E3G1
names: Similarity
messages: Belongs to the calponin family.

9915:LOC109554587
gene id: 9915:LOC109554587
uniprot id: A0A6P5AVK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIII family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9915:NOTCH4
gene id: 9915:NOTCH4
uniprot id: A0A6P5DUV6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:TAF5
gene id: 9915:TAF5
uniprot id: A0A6P5B7S6
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

9915:TMED7
gene id: 9915:TMED7
uniprot id: A0A6P5CDT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

9915:ATP6V1C1
gene id: 9915:ATP6V1C1
uniprot id: A0A6P5CTU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

9915:CANT1
gene id: 9915:CANT1
uniprot id: A0A6P5DJE5
names: Similarity
messages: Belongs to the apyrase family.

9915:LOC109574803
gene id: 9915:LOC109574803
uniprot id: A0A6P5DMM3
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9915:LOC109555657
gene id: 9915:LOC109555657
uniprot id: A0A6P5B042
names: Subcellular Location Annotation
messages: Nucleus

9915:HOXA9
gene id: 9915:HOXA9
uniprot id: A0A6P5BQU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

9915:LOC109561196
gene id: 9915:LOC109561196
uniprot id: A0A6P5C1M9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CNTD2
gene id: 9915:CNTD2
uniprot id: A0A6P5DA18
names: Similarity
messages: Belongs to the cyclin family.

9915:LOC109556077
gene id: 9915:LOC109556077
uniprot id: A0A6P5B238
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:PFDN1
gene id: 9915:PFDN1
uniprot id: A0A6P5C557
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9915:LOC109558540
gene id: 9915:LOC109558540
uniprot id: A0A6P5BEB9
names: Similarity
messages: Belongs to the caprin family.

9915:LOC109564267
gene id: 9915:LOC109564267
uniprot id: A0A6P5CE09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:LOC109575157
gene id: 9915:LOC109575157
uniprot id: A0A6P5DNG4
names: Subcellular Location Annotation
messages: Membrane

9915:ADAM23
gene id: 9915:ADAM23
uniprot id: A0A6P5D202
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:THADA
gene id: 9915:THADA
uniprot id: A0A6P5CJG1
uniprot id: A0A6P5CL54
names: Similarity
messages: Belongs to the THADA family.

9915:YIPF1
gene id: 9915:YIPF1
uniprot id: A0A6P5B7X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9915:LOC109561054
gene id: 9915:LOC109561054
uniprot id: A0A6P5C0L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DGKQ
gene id: 9915:DGKQ
uniprot id: A0A6P5BZH8
uniprot id: A0A6P5BZU2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:LIG3
gene id: 9915:LIG3
uniprot id: A0A6P5DF12
uniprot id: A0A6P5DHZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

9915:CREB5
gene id: 9915:CREB5
uniprot id: A0A6P5B7I4
uniprot id: A0A6P5BQS5
uniprot id: A0A6P5BQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9915:LOC109569481
gene id: 9915:LOC109569481
uniprot id: A0A6P5CXG6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CPSF6
gene id: 9915:CPSF6
uniprot id: A0A6P5BT45
uniprot id: A0A6P5BT47
uniprot id: A0A6P5BT48
uniprot id: A0A6P5BT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

9915:UHRF2
gene id: 9915:UHRF2
uniprot id: A0A6P5C7H3
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109565926
gene id: 9915:LOC109565926
uniprot id: A0A6P5CJR0
names: Similarity
messages: Belongs to the DCK/DGK family.

9915:ACTN1
gene id: 9915:ACTN1
uniprot id: A0A6P5CG41
uniprot id: A0A6P5CGS4
uniprot id: A0A6P5CH48
names: Similarity
messages: Belongs to the alpha-actinin family.

9915:DMAP1
gene id: 9915:DMAP1
uniprot id: A0A6P5BPF5
names: Subcellular Location Annotation
messages: Nucleus

9915:CD34
gene id: 9915:CD34
uniprot id: A0A6P5D2J4
uniprot id: A0A6P5D3U5
names: Subcellular Location Annotation
messages: Membrane

9915:PRR15L
gene id: 9915:PRR15L
uniprot id: A0A6P5DFI5
uniprot id: A0A6P5DH36
uniprot id: A0A6P5DHX5
names: Similarity
messages: Belongs to the PRR15 family.

9915:APOE
gene id: 9915:APOE
uniprot id: A0A6P5DAK4
uniprot id: A0A6P5DCV1
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9915:MON2
gene id: 9915:MON2
uniprot id: A0A6P5BTA4
uniprot id: A0A6P5BTA5
uniprot id: A0A6P5BTA6
uniprot id: A0A6P5BTA7
names: Similarity
messages: Belongs to the MON2 family.

9915:EPN3
gene id: 9915:EPN3
uniprot id: A0A6P5DI90
uniprot id: A0A6P5DLC8
names: Similarity
messages: Belongs to the epsin family.

9915:LOC109571546
gene id: 9915:LOC109571546
uniprot id: A0A6P5D651
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:GRAP
gene id: 9915:GRAP
uniprot id: A0A6P5DCK0
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

9915:FAM208B
gene id: 9915:FAM208B
uniprot id: A0A6P5CS54
uniprot id: A0A6P5CT39
uniprot id: A0A6P5CTF0
uniprot id: A0A6P5CUJ3
uniprot id: A0A6P5CVL0
uniprot id: A0A6P5CVL7
names: Similarity
messages: Belongs to the TASOR family.

9915:PRRT2
gene id: 9915:PRRT2
uniprot id: A0A6P5DZD6
uniprot id: A0A6P5E218
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9915:PHF10
gene id: 9915:PHF10
uniprot id: A0A6P5CBV9
uniprot id: A0A6P5CD64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAYP family.
messages: Nucleus

9915:ERN2
gene id: 9915:ERN2
uniprot id: A0A6P5DYR0
uniprot id: A0A6P5DYR9
uniprot id: A0A6P5DZK3
uniprot id: A0A6P5E278
uniprot id: A0A6P5E2N5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109568871
gene id: 9915:LOC109568871
uniprot id: A0A6P5CVQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:OPALIN
gene id: 9915:OPALIN
uniprot id: A0A6P5E0J4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
messages: Membrane

9915:KHDRBS3
gene id: 9915:KHDRBS3
uniprot id: A0A6P5CSF8
names: Similarity
messages: Belongs to the KHDRBS family.

9915:EPN2
gene id: 9915:EPN2
uniprot id: A0A6P5DFN9
uniprot id: A0A6P5DI16
names: Similarity
messages: Belongs to the epsin family.

9915:EVPL
gene id: 9915:EVPL
uniprot id: A0A6P5DJV2
names: Subcellular Location Annotation
messages: cytoskeleton

9915:MAATS1
gene id: 9915:MAATS1
uniprot id: A0A6P5DUW3
uniprot id: A0A6P5DVM3
uniprot id: A0A6P5DZA9
names: Similarity
messages: Belongs to the CFAP91 family.

9915:RYBP
gene id: 9915:RYBP
uniprot id: A0A6P5DP58
names: Subcellular Location Annotation
messages: Nucleus

9915:ILK
gene id: 9915:ILK
uniprot id: A0A6P5D0X6
names: Subcellular Location Annotation
messages: focal adhesion
messages: lamellipodium
messages: sarcomere

9915:C6
gene id: 9915:C6
uniprot id: A0A6P5DK18
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Component of the membrane attack complex (MAC). MAC assembly is initiated by proteolytic cleavage of C5 into C5a and C5b. C5b binds sequentially C6, C7, C8 and 12-14 copies of the pore-forming subunit C9.
messages: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:RBM48
gene id: 9915:RBM48
uniprot id: A0A6P5BDT5
names: Similarity
messages: Belongs to the RBM48 family.

9915:SKOR2
gene id: 9915:SKOR2
uniprot id: A0A6P5DYK2
names: Similarity
messages: Belongs to the SKI family.

9915:FLOT2
gene id: 9915:FLOT2
uniprot id: A0A6P5DGN6
uniprot id: A0A6P5DI46
uniprot id: A0A6P5DJ30
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: caveola

9915:TMBIM4
gene id: 9915:TMBIM4
uniprot id: A0A6P5BT73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9915:LOC109566511
gene id: 9915:LOC109566511
uniprot id: A0A6P5CLX0
uniprot id: A0A6P5CMM0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm

9915:PTPRG
gene id: 9915:PTPRG
uniprot id: A0A6P5DND8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

9915:SLC27A4
gene id: 9915:SLC27A4
uniprot id: A0A6P5CNM2
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:LOC109569348
gene id: 9915:LOC109569348
uniprot id: A0A6P5CWZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GPKOW
gene id: 9915:GPKOW
uniprot id: A0A6P5AYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MOS2 family.
messages: Nucleus

9915:ARAP3
gene id: 9915:ARAP3
uniprot id: A0A6P5C0F1
names: Subcellular Location Annotation
messages: Cytoplasm

9915:PSPN
gene id: 9915:PSPN
uniprot id: A0A6P5C0Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9915:KCNG4
gene id: 9915:KCNG4
uniprot id: A0A6P5DC78
names: Subcellular Location Annotation
messages: Membrane

9915:SLC25A33
gene id: 9915:SLC25A33
uniprot id: A0A6P5D666
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:KEG07 p02
gene id: 9915:KEG07_p02
uniprot id: E7BTJ0
uniprot id: Q71PB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

9915:GCLC
gene id: 9915:GCLC
uniprot id: A0A6P5DTA9
uniprot id: A0A6P5DUL3
uniprot id: A0A6P5DX33
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

9915:NPFFR2
gene id: 9915:NPFFR2
uniprot id: A0A6P5BX45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9915:VDAC2
gene id: 9915:VDAC2
uniprot id: A0A6P5BIP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

9915:AGXT2
gene id: 9915:AGXT2
uniprot id: A0A6P5DN32
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9915:FAR2
gene id: 9915:FAR2
uniprot id: A0A6P5BUW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9915:LOC109561308
gene id: 9915:LOC109561308
uniprot id: A0A6P5C1Z2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

9915:LOC109556264
gene id: 9915:LOC109556264
uniprot id: A0A6P5BHY0
uniprot id: A0A6P5BP72
uniprot id: A0A6P5BP74
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

9915:TRAF5
gene id: 9915:TRAF5
uniprot id: A0A6P5D459
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9915:CYFIP2
gene id: 9915:CYFIP2
uniprot id: A0A6P5C5Z5
names: Similarity
messages: Belongs to the CYFIP family.

9915:MSN
gene id: 9915:MSN
uniprot id: A0A6P5BLS9
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton
messages: microvillus

9915:FXYD2
gene id: 9915:FXYD2
uniprot id: A0A6P5CYG6
uniprot id: A0A6P5D207
names: Similarity
messages: Belongs to the FXYD family.

9915:MYO9B
gene id: 9915:MYO9B
uniprot id: A0A6P5C1I8
uniprot id: A0A6P5C1J3
uniprot id: A0A6P5C1K1
uniprot id: A0A6P5C1K4
uniprot id: A0A6P5C1K9
uniprot id: A0A6P5C1W2
uniprot id: A0A6P5C1W6
uniprot id: A0A6P5C1X2
uniprot id: A0A6P5C1X5
uniprot id: A0A6P5C2N2
uniprot id: A0A6P5C2N7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9915:ZNF232
gene id: 9915:ZNF232
uniprot id: A0A6P5DM52
names: Subcellular Location Annotation
messages: Nucleus

9915:MPPED2
gene id: 9915:MPPED2
uniprot id: A0A6P5CZD7
names: Similarity
messages: Belongs to the UPF0046 family.

9915:PABPC4
gene id: 9915:PABPC4
uniprot id: A0A6P5B4A1
uniprot id: A0A6P5B4A5
uniprot id: A0A6P5B8X5
uniprot id: A0A6P5B8X9
uniprot id: A0A6P5BIL2
uniprot id: A0A6P5BPJ1
uniprot id: A0A6P5BPJ3
uniprot id: A0A6P5BPL8
uniprot id: A0A6P5BPM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

9915:SEMA5B
gene id: 9915:SEMA5B
uniprot id: A0A6P5B5S4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109568189
gene id: 9915:LOC109568189
uniprot id: A0A6P5B2C4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

9915:LOC109569396
gene id: 9915:LOC109569396
uniprot id: A0A6P5CZP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DLG5
gene id: 9915:DLG5
uniprot id: A0A6P5AY85
uniprot id: A0A6P5BA65
uniprot id: A0A6P5BI33
uniprot id: A0A6P5BIG0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:SIGMAR1
gene id: 9915:SIGMAR1
uniprot id: A0A6P5CA43
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cell junction
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Lipid droplet
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: Postsynaptic density membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

9915:UBE3C
gene id: 9915:UBE3C
uniprot id: A0A6P5BRD3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ZNF397
gene id: 9915:ZNF397
uniprot id: A0A6P5DUR4
uniprot id: A0A6P5DV00
uniprot id: A0A6P5DVY5
uniprot id: A0A6P5DYF9
names: Subcellular Location Annotation
messages: Nucleus

9915:AKIRIN1
gene id: 9915:AKIRIN1
uniprot id: A0A6P5BIM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

9915:CD200
gene id: 9915:CD200
uniprot id: A0A6P5D9Y0
uniprot id: A0A6P5DAD7
uniprot id: A0A6P5DBG7
uniprot id: A0A6P5DBN7
uniprot id: A0A6P5DDL7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109553282
gene id: 9915:LOC109553282
uniprot id: A0A6P5APS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:LOC109558735
gene id: 9915:LOC109558735
uniprot id: A0A6P5BS80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ARRDC2
gene id: 9915:ARRDC2
uniprot id: A0A6P5C1T0
uniprot id: A0A6P5C2H2
names: Similarity
messages: Belongs to the arrestin family.

9915:LOC109554320
gene id: 9915:LOC109554320
uniprot id: A0A6P5BC84
names: Subcellular Location Annotation
messages: Membrane

9915:A3GALT2
gene id: 9915:A3GALT2
uniprot id: A0A6P5DRR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9915:SHBG
gene id: 9915:SHBG
uniprot id: A0A6P5DI24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109555054
gene id: 9915:LOC109555054
uniprot id: A0A6P5BEM8
names: Similarity
messages: Belongs to the histone H2B family.

9915:RRP15
gene id: 9915:RRP15
uniprot id: A0A6P5D5I9
names: Similarity
messages: Belongs to the RRP15 family.

9915:TNFSF10
gene id: 9915:TNFSF10
uniprot id: A0A6P5B9P9
uniprot id: A0A6P5BRL7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tumor necrosis factor family.
messages: Homotrimer.
messages: Membrane
messages: Secreted

9915:GPHA2
gene id: 9915:GPHA2
uniprot id: A0A6P5BDP3
names: Caution
names: Function
names: Similarity
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

9915:BTG2
gene id: 9915:BTG2
uniprot id: A0A6P5D1U7
names: Similarity
messages: Belongs to the BTG family.

9915:LOC109575975
gene id: 9915:LOC109575975
uniprot id: A0A6P5DRQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:SYPL2
gene id: 9915:SYPL2
uniprot id: A0A6P5BNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

9915:PDGFD
gene id: 9915:PDGFD
uniprot id: A0A6P5CYJ5
uniprot id: A0A6P5D235
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Homodimer; disulfide-linked. Interacts with PDGFRB homodimers, and with heterodimers formed by PDGFRA and PDGFRB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:S100A10
gene id: 9915:S100A10
uniprot id: A0A6P5BL33
names: Function
names: Similarity
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.
messages: Belongs to the S-100 family.

9915:ADAM11
gene id: 9915:ADAM11
uniprot id: A0A6P5DM78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CLDN3
gene id: 9915:CLDN3
uniprot id: A0A6P5E0S8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:ADGRA2
gene id: 9915:ADGRA2
uniprot id: A0A6P5B8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9915:FHL5
gene id: 9915:FHL5
uniprot id: A0A6P5CB89
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

9915:DEF8
gene id: 9915:DEF8
uniprot id: A0A6P5DA30
uniprot id: A0A6P5DBW0
uniprot id: A0A6P5DDC5
names: Similarity
messages: Belongs to the DEF8 family.

9915:USH1G
gene id: 9915:USH1G
uniprot id: A0A6P5DF97
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:HNRNPAB
gene id: 9915:HNRNPAB
uniprot id: A0A6P5C3Y8
uniprot id: A0A6P5C427
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:LOC109562638
gene id: 9915:LOC109562638
uniprot id: A0A6P5C6H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:LOC109567291
gene id: 9915:LOC109567291
uniprot id: A0A6P5CQZ9
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

9915:TOMM20
gene id: 9915:TOMM20
uniprot id: A0A6P5BIF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

9915:TSPAN2
gene id: 9915:TSPAN2
uniprot id: A0A6P5BGX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:C1H21orf59
gene id: 9915:C1H21orf59
uniprot id: A0A6P5BJE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

9915:TSR3
gene id: 9915:TSR3
uniprot id: A0A6P5DY67
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1248 (Psi1248) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109571654
gene id: 9915:LOC109571654
uniprot id: A0A6P5D9V8
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109554052
gene id: 9915:LOC109554052
uniprot id: A0A6P5BJ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RFLNB
gene id: 9915:RFLNB
uniprot id: A0A6P5DE97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

9915:KLHL36
gene id: 9915:KLHL36
uniprot id: A0A6P5D8F0
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

9915:AP4M1
gene id: 9915:AP4M1
uniprot id: A0A6P5DXF7
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9915:LOC109557294
gene id: 9915:LOC109557294
uniprot id: A0A6P5B6K8
uniprot id: A0A6P5BB11
uniprot id: A0A6P5BJS1
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:NASP
gene id: 9915:NASP
uniprot id: A0A6P5B3M2
uniprot id: A0A6P5BI98
uniprot id: A0A6P5BPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

9915:ADAMTS10
gene id: 9915:ADAMTS10
uniprot id: A0A6P5C2Z9
uniprot id: A0A6P5C3Z0
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:COPG2
gene id: 9915:COPG2
uniprot id: A0A6P5BCD8
uniprot id: A0A6P5BKN5
uniprot id: A0A6P5BR44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

9915:LOC109564316
gene id: 9915:LOC109564316
uniprot id: A0A6P5CDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EMC9
gene id: 9915:EMC9
uniprot id: A0A6P5CDS9
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

9915:LOC109554403
gene id: 9915:LOC109554403
uniprot id: A0A6P5BK44
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9915:NOL8
gene id: 9915:NOL8
uniprot id: A0A6P5C8W8
uniprot id: A0A6P5C992
uniprot id: A0A6P5C9I2
uniprot id: A0A6P5CAG3
names: Subcellular Location Annotation
messages: nucleolus

9915:RNF7
gene id: 9915:RNF7
uniprot id: A0A6P5BV34
names: Similarity
messages: Belongs to the RING-box family.

9915:PREB
gene id: 9915:PREB
uniprot id: A0A6P5CJ77
uniprot id: A0A6P5CKC7
uniprot id: A0A6P5CMI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER.
messages: Interacts with SAR1B (GDP-bound form). Interacts with MIA2; recruits PREB to endoplasmic reticulum exit sites.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene (PRL) promoter and seems to activate transcription.

9915:OGDHL
gene id: 9915:OGDHL
uniprot id: A0A6P5AR21
uniprot id: A0A6P5B9K9
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

9915:SPSB2
gene id: 9915:SPSB2
uniprot id: A0A6P5BMP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

9915:LOC109577728
gene id: 9915:LOC109577728
uniprot id: A0A6P5DYQ3
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109569614
gene id: 9915:LOC109569614
uniprot id: A0A6P5CYF0
uniprot id: A0A6P5D0X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9915:SUMF1
gene id: 9915:SUMF1
uniprot id: A0A6P5DQ60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

9915:LOC109570212
gene id: 9915:LOC109570212
uniprot id: A0A6P5D3I6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109569079
gene id: 9915:LOC109569079
uniprot id: A0A6P5CWE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KIF2B
gene id: 9915:KIF2B
uniprot id: A0A6P5DDP9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109554763
gene id: 9915:LOC109554763
uniprot id: A0A6P5BL06
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:E2F7
gene id: 9915:E2F7
uniprot id: A0A6P5BSD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:SCNN1B
gene id: 9915:SCNN1B
uniprot id: A0A6P5DWS7
names: Subcellular Location Annotation
messages: Membrane

9915:RACK1
gene id: 9915:RACK1
uniprot id: A0A6P5C5G9
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

9915:LOC109557559
gene id: 9915:LOC109557559
uniprot id: A0A6P5B7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

9915:RAE1
gene id: 9915:RAE1
uniprot id: A0A6P5CNP2
uniprot id: A0A6P5CS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

9915:ELMO3
gene id: 9915:ELMO3
uniprot id: A0A6P5DAG5
uniprot id: A0A6P5DCK3
uniprot id: A0A6P5DCL8
uniprot id: A0A6P5DDR5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

9915:LOC109557706
gene id: 9915:LOC109557706
uniprot id: A0A6P5BR62
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

9915:PTPRF
gene id: 9915:PTPRF
uniprot id: A0A6P5B3Y1
uniprot id: A0A6P5B8J6
uniprot id: A0A6P5BIE6
uniprot id: A0A6P5BPH1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

9915:GHRL
gene id: 9915:GHRL
uniprot id: A0A6P5DNA0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the motilin family.
messages: Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
messages: O-octanoylation is essential for ghrelin activity.
messages: Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
messages: Secreted

9915:LOC109576837
gene id: 9915:LOC109576837
uniprot id: A0A6P5DVG0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:CER1
gene id: 9915:CER1
uniprot id: A0A6P5C832
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:LOC109569149
gene id: 9915:LOC109569149
uniprot id: A0A6P5CYU0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109572397
gene id: 9915:LOC109572397
uniprot id: A0A6P5D8V6
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9915:LOC109561023
gene id: 9915:LOC109561023
uniprot id: A0A6P5C0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PEX5L
gene id: 9915:PEX5L
uniprot id: A0A6P5BRD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane

9915:APOA5
gene id: 9915:APOA5
uniprot id: A0A6P5D055
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

9915:SORCS3
gene id: 9915:SORCS3
uniprot id: A0A6P5APM6
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

9915:YDJC
gene id: 9915:YDJC
uniprot id: A0A6P5D7C9
uniprot id: A0A6P5D8B7
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

9915:SGF29
gene id: 9915:SGF29
uniprot id: A0A6P5DYG3
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109561003
gene id: 9915:LOC109561003
uniprot id: A0A6P5C0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DEFB116
gene id: 9915:DEFB116
uniprot id: A0A6P5CT45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:FAM173B
gene id: 9915:FAM173B
uniprot id: A0A6P5DJM4
uniprot id: A0A6P5DKY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

9915:MSMP
gene id: 9915:MSMP
uniprot id: A0A6P5C875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-microseminoprotein family.
messages: Secreted

9915:ZNF483
gene id: 9915:ZNF483
uniprot id: A0A6P5C6F9
names: Subcellular Location Annotation
messages: Nucleus

9915:PMP22
gene id: 9915:PMP22
uniprot id: A0A6P5DHW5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Might be involved in growth regulation, and in myelinization in the peripheral nervous system.

9915:MYLK
gene id: 9915:MYLK
uniprot id: A0A6P5BN78
uniprot id: A0A6P5BNA5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9915:TCEA1
gene id: 9915:TCEA1
uniprot id: A0A6P5CV21
uniprot id: A0A6P5CXA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

9915:AP1G1
gene id: 9915:AP1G1
uniprot id: A0A6P5D8Z0
uniprot id: A0A6P5DAU8
uniprot id: A0A6P5DBC6
uniprot id: A0A6P5DCE3
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9915:LOC109572915
gene id: 9915:LOC109572915
uniprot id: A0A6P5DBE6
names: Subcellular Location Annotation
messages: Membrane

9915:PPM1D
gene id: 9915:PPM1D
uniprot id: A0A6P5DEP5
names: Similarity
messages: Belongs to the PP2C family.

9915:LOC109565330
gene id: 9915:LOC109565330
uniprot id: A0A6P5CH14
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:LOC109570044
gene id: 9915:LOC109570044
uniprot id: A0A6P5D0L7
names: Similarity
messages: Belongs to the globin family.

9915:DHCR7
gene id: 9915:DHCR7
uniprot id: A0A6P5B0U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

9915:F13A1
gene id: 9915:F13A1
uniprot id: A0A6P5DTD1
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9915:ASIC2
gene id: 9915:ASIC2
uniprot id: A0A6P5DCA7
names: Subcellular Location Annotation
messages: Membrane

9915:MARK3
gene id: 9915:MARK3
uniprot id: A0A6P5DLD6
uniprot id: A0A6P5DLD9
uniprot id: A0A6P5DM25
uniprot id: A0A6P5DM28
uniprot id: A0A6P5DMT2
uniprot id: A0A6P5DMT7
uniprot id: A0A6P5DPS6
uniprot id: A0A6P5DPT2
uniprot id: A0A6P5DQ43
uniprot id: A0A6P5DQ48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9915:LOC109565615
gene id: 9915:LOC109565615
uniprot id: A0A6P5CGL6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SNAP91
gene id: 9915:SNAP91
uniprot id: A0A6P5CA73
uniprot id: A0A6P5CAN6
uniprot id: A0A6P5CAY9
uniprot id: A0A6P5CC21
names: Similarity
messages: Belongs to the PICALM/SNAP91 family.

9915:LOC109560636
gene id: 9915:LOC109560636
uniprot id: A0A6P5BZ40
names: Similarity
messages: Belongs to the cornifelin family.

9915:TECR
gene id: 9915:TECR
uniprot id: A0A6P5C1Q2
uniprot id: A0A6P5C242
uniprot id: A0A6P5C254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:HSP90B1
gene id: 9915:HSP90B1
uniprot id: A0A6P5BU81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 90 family.
messages: Melanosome

9915:SLC9A3R2
gene id: 9915:SLC9A3R2
uniprot id: A0A6P5DYV2
uniprot id: A0A6P5E2S9
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.

9915:LOC109569032
gene id: 9915:LOC109569032
uniprot id: A0A6P5CXQ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:RGMB
gene id: 9915:RGMB
uniprot id: A0A6P5C0W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9915:MEP1B
gene id: 9915:MEP1B
uniprot id: A0A6P5DZP2
uniprot id: A0A6P5E063
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109568618
gene id: 9915:LOC109568618
uniprot id: A0A6P5CWL9
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109579153
gene id: 9915:LOC109579153
uniprot id: A0A6P5E1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

9915:C23H6orf89
gene id: 9915:C23H6orf89
uniprot id: A0A6P5DTQ3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9915:RPS24
gene id: 9915:RPS24
uniprot id: A0A6P5ASC9
uniprot id: A0A6P5AYW0
uniprot id: A0A6P5BAQ5
uniprot id: A0A6P5BIH8
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.
messages: Required for processing of pre-rRNA and maturation of 40S ribosomal subunits.

9915:CPXM1
gene id: 9915:CPXM1
uniprot id: A0A6P5CN68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

9915:TXNRD2
gene id: 9915:TXNRD2
uniprot id: A0A6P5D7Q1
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

9915:LOC109569134
gene id: 9915:LOC109569134
uniprot id: A0A6P5CXX3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MARCKS
gene id: 9915:MARCKS
uniprot id: A0A6P5CAF5
names: Similarity
messages: Belongs to the MARCKS family.

9915:LOC109554710
gene id: 9915:LOC109554710
uniprot id: A0A6P5AW04
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:LOC109563955
gene id: 9915:LOC109563955
uniprot id: A0A6P5CBL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MNS1
gene id: 9915:MNS1
uniprot id: A0A6P5CEM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MNS1 family.
messages: Nucleus
messages: cilium axoneme
messages: flagellum axoneme

9915:SLCO3A1
gene id: 9915:SLCO3A1
uniprot id: A0A6P5DN71
uniprot id: A0A6P5DQ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

9915:MYH11
gene id: 9915:MYH11
uniprot id: A0A6P5DX34
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9915:POU3F4
gene id: 9915:POU3F4
uniprot id: A0A6P5B5A7
uniprot id: A0A6P5BGJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9915:TCTA
gene id: 9915:TCTA
uniprot id: A0A6P5DRM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTA family.
messages: May be required for cellular fusion during osteoclastogenesis.
messages: Membrane

9915:SLC29A4
gene id: 9915:SLC29A4
uniprot id: A0A6P5E074
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC29A/ENT transporter (TC 2.A.57) family.
messages: Membrane

9915:BPGM
gene id: 9915:BPGM
uniprot id: A0A6P5BR51
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

9915:SDF4
gene id: 9915:SDF4
uniprot id: A0A6P5D5F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

9915:SGO1
gene id: 9915:SGO1
uniprot id: A0A6P5C3X5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

9915:NUTF2
gene id: 9915:NUTF2
uniprot id: A0A6P5DCJ1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

9915:AMN
gene id: 9915:AMN
uniprot id: A0A6P5DNN0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:TOB2
gene id: 9915:TOB2
uniprot id: A0A6P5BW06
names: Similarity
messages: Belongs to the BTG family.

9915:LOC109574015
gene id: 9915:LOC109574015
uniprot id: A0A6P5DJ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM187 family.
messages: Membrane

9915:C16H1orf27
gene id: 9915:C16H1orf27
uniprot id: A0A6P5D0I8
uniprot id: A0A6P5D480
names: Function
names: Similarity
messages: Belongs to the ODR-4 family.
messages: May play a role in the trafficking of a subset of G-protein coupled receptors.

9915:LOC109569384
gene id: 9915:LOC109569384
uniprot id: A0A6P5CX47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ATP6AP1L
gene id: 9915:ATP6AP1L
uniprot id: A0A6P5C5R7
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

9915:RABEP2
gene id: 9915:RABEP2
uniprot id: A0A6P5DWX2
uniprot id: A0A6P5DX12
uniprot id: A0A6P5DXX4
uniprot id: A0A6P5DXX8
uniprot id: A0A6P5E0K1
uniprot id: A0A6P5E0K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rabaptin family.
messages: Early endosome
messages: Endosome
messages: centrosome
messages: cilium basal body

9915:RAB3IP
gene id: 9915:RAB3IP
uniprot id: A0A6P5BNM4
uniprot id: A0A6P5BT25
uniprot id: A0A6P5BT26
names: Similarity
messages: Belongs to the SEC2 family.

9915:LOC109570296
gene id: 9915:LOC109570296
uniprot id: A0A6P5D0V1
names: Similarity
messages: Belongs to the COX20 family.

9915:LOC109578136
gene id: 9915:LOC109578136
uniprot id: A0A6P5DWE0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:GYS1
gene id: 9915:GYS1
uniprot id: A0A6P5D9H4
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

9915:LOC109570045
gene id: 9915:LOC109570045
uniprot id: A0A6P5D365
names: Similarity
messages: Belongs to the globin family.

9915:LOC109574304
gene id: 9915:LOC109574304
uniprot id: A0A6P5DI60
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:DNMT3B
gene id: 9915:DNMT3B
uniprot id: A0A6P5CP07
uniprot id: A0A6P5CQ41
uniprot id: A0A6P5CQM5
uniprot id: A0A6P5CRF0
uniprot id: A0A6P5CSG7
uniprot id: A0A6P5CSH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
messages: Nucleus

9915:LBP
gene id: 9915:LBP
uniprot id: A0A6P5CQJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Plays a role in the innate immune response. Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria. Acts as an affinity enhancer for CD14, facilitating its association with LPS. Promotes the release of cytokines in response to bacterial lipopolysaccharide.
messages: Secreted
messages: When bound to LPS, interacts (via C-terminus) with soluble and membrane-bound CD14.

9915:PPP1R15B
gene id: 9915:PPP1R15B
uniprot id: A0A6P5D1N6
names: Similarity
messages: Belongs to the PPP1R15 family.

9915:GPT
gene id: 9915:GPT
uniprot id: A0A6P5CST6
uniprot id: A0A6P5CTV1
uniprot id: A0A6P5CVB0
uniprot id: A0A6P5CWD0
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

9915:LOC109565970
gene id: 9915:LOC109565970
uniprot id: A0A6P5CIR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

9915:CARNMT1
gene id: 9915:CARNMT1
uniprot id: A0A6P5C841
names: Similarity
messages: Belongs to the carnosine N-methyltransferase family.

9915:LOC109565645
gene id: 9915:LOC109565645
uniprot id: A0A6P5CJN1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558890
gene id: 9915:LOC109558890
uniprot id: A0A6P5BEX8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109570221
gene id: 9915:LOC109570221
uniprot id: A0A6P5D0X1
names: Similarity
messages: Belongs to the PDCD5 family.

9915:LOC109561176
gene id: 9915:LOC109561176
uniprot id: A0A6P5C0W4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SELE
gene id: 9915:SELE
uniprot id: A0A6P5CZY3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selectin/LECAM family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:ODF1
gene id: 9915:ODF1
uniprot id: A0A6P5CW61
names: Function
messages: Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

9915:OVOL3
gene id: 9915:OVOL3
uniprot id: A0A6P5DBC2
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109574370
gene id: 9915:LOC109574370
uniprot id: A0A6P5DII1
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

9915:NMBR
gene id: 9915:NMBR
uniprot id: A0A6P5CAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:P2RX6
gene id: 9915:P2RX6
uniprot id: A0A6P5D506
uniprot id: A0A6P5D5U2
uniprot id: A0A6P5D6U4
uniprot id: A0A6P5D8D5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9915:CALY
gene id: 9915:CALY
uniprot id: A0A6P5BGW9
names: Similarity
messages: Belongs to the NSG family.

9915:LOC109579032
gene id: 9915:LOC109579032
uniprot id: A0A6P5E440
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:VASN
gene id: 9915:VASN
uniprot id: A0A6P5E1J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109569397
gene id: 9915:LOC109569397
uniprot id: A0A6P5CYT3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HOMEZ
gene id: 9915:HOMEZ
uniprot id: A0A6P5CDI2
uniprot id: A0A6P5CEN0
names: Subcellular Location Annotation
messages: Nucleus

9915:MRGPRF
gene id: 9915:MRGPRF
uniprot id: A0A6P5BKM1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:TTC39A
gene id: 9915:TTC39A
uniprot id: A0A6P5BJC3
names: Similarity
messages: Belongs to the TTC39 family.

9915:LOC109572161
gene id: 9915:LOC109572161
uniprot id: A0A6P5D7P7
names: Subcellular Location Annotation
messages: Nucleus

9915:POU4F2
gene id: 9915:POU4F2
uniprot id: A0A6P5D375
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9915:PSMB4
gene id: 9915:PSMB4
uniprot id: A0A6P5BL96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

9915:FBLN7
gene id: 9915:FBLN7
uniprot id: A0A6P5CGT8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NUDC
gene id: 9915:NUDC
uniprot id: A0A6P5DCL5
uniprot id: A0A6P5DFT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

9915:LGI1
gene id: 9915:LGI1
uniprot id: A0A6P5AWH6
names: Subcellular Location Annotation
messages: Secreted

9915:SCD5
gene id: 9915:SCD5
uniprot id: A0A6P5BZW7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane
messages: The histidine box domains are involved in binding the catalytic metal ions.

9915:SLC15A2
gene id: 9915:SLC15A2
uniprot id: A0A6P5BJ60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Interacts (via extracellular domain region) with trypsin.
messages: Membrane

9915:SLC16A13
gene id: 9915:SLC16A13
uniprot id: A0A6P5DCJ5
names: Subcellular Location Annotation
messages: Membrane

9915:FAM198B
gene id: 9915:FAM198B
uniprot id: A0A6P5D849
names: Similarity
messages: Belongs to the GASK family.

9915:LOC109577385
gene id: 9915:LOC109577385
uniprot id: A0A6P5DY72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:CSN1S1
gene id: 9915:CSN1S1
uniprot id: A0A6P5BYP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

9915:EIF1AX
gene id: 9915:EIF1AX
uniprot id: A0A6P5B3G8
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

9915:INO80D
gene id: 9915:INO80D
uniprot id: A0A6P5D2F1
names: Subcellular Location Annotation
messages: Nucleus

9915:KCNAB1
gene id: 9915:KCNAB1
uniprot id: A0A6P5BFD5
uniprot id: A0A6P5BSM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9915:LOC109554078
gene id: 9915:LOC109554078
uniprot id: A0A6P5AZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ARRB2
gene id: 9915:ARRB2
uniprot id: A0A6P5DF43
names: Similarity
messages: Belongs to the arrestin family.

9915:FAM118B
gene id: 9915:FAM118B
uniprot id: A0A6P5B1M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM118 family.
messages: Cajal body
messages: May play a role in Cajal bodies formation.

9915:SELENOO
gene id: 9915:SELENOO
uniprot id: A0A6P5CS86
uniprot id: A0A6P5CSK1
uniprot id: A0A6P5CTJ8
uniprot id: A0A6P5CUJ5
names: Similarity
messages: Belongs to the SELO family.

9915:UBE4A
gene id: 9915:UBE4A
uniprot id: A0A6P5CX16
uniprot id: A0A6P5CZG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

9915:CNOT6L
gene id: 9915:CNOT6L
uniprot id: A0A6P5BYZ7
uniprot id: A0A6P5BZD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

9915:RPA4
gene id: 9915:RPA4
uniprot id: A0A6P5BLN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

9915:HNRNPDL
gene id: 9915:HNRNPDL
uniprot id: A0A6P5BZ33
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:SPX
gene id: 9915:SPX
uniprot id: A0A6P5BUV9
uniprot id: A0A6P5BUW3
uniprot id: A0A6P5BV38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spexin family.
messages: Secreted

9915:LOC109558478
gene id: 9915:LOC109558478
uniprot id: A0A6P5BS03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109571428
gene id: 9915:LOC109571428
uniprot id: A0A6P5D599
uniprot id: A0A6P5D5Q0
uniprot id: A0A6P5D948
names: Similarity
messages: Belongs to the AAA ATPase family.

9915:ATRAID
gene id: 9915:ATRAID
uniprot id: A0A6P5CI86
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:RBP2
gene id: 9915:RBP2
uniprot id: A0A6P5BVP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9915:LOC109562656
gene id: 9915:LOC109562656
uniprot id: A0A6P5C6Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:LOC109569477
gene id: 9915:LOC109569477
uniprot id: A0A6P5CZZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BCL2L11
gene id: 9915:BCL2L11
uniprot id: A0A6P5CI87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Bcl-2 family.
messages: Forms heterodimers with a number of antiapoptotic Bcl-2 proteins including MCL1, BCL2, BCL2L1 isoform Bcl-X(L), BCL2A1/BFL-1.
messages: Induces apoptosis and anoikis.

9915:SV2B
gene id: 9915:SV2B
uniprot id: A0A6P5DN07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

9915:IL1RAPL2
gene id: 9915:IL1RAPL2
uniprot id: A0A6P5BMS4
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9915:FAM53C
gene id: 9915:FAM53C
uniprot id: A0A6P5C4P6
names: Similarity
messages: Belongs to the FAM53 family.

9915:SEPT14
gene id: 9915:SEPT14
uniprot id: A0A6P5E3S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9915:LOC109558364
gene id: 9915:LOC109558364
uniprot id: A0A6P5BAN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ACTL6B
gene id: 9915:ACTL6B
uniprot id: A0A6P5E327
names: Similarity
messages: Belongs to the actin family.

9915:TIMP2
gene id: 9915:TIMP2
uniprot id: A0A6P5DFZ5
names: Similarity
names: Subunit
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: Interacts (via the C-terminal) with MMP2 (via the C-terminal PEX domain); the interaction inhibits the MMP2 activity.

9915:TFF2
gene id: 9915:TFF2
uniprot id: A0A6P5CCZ2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PAX3
gene id: 9915:PAX3
uniprot id: A0A6P5DRU0
uniprot id: A0A6P5DVM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9915:CLVS2
gene id: 9915:CLVS2
uniprot id: A0A6P5C9W2
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

9915:PHLDA1
gene id: 9915:PHLDA1
uniprot id: A0A6P5BSB7
names: Subcellular Location Annotation
messages: Cytoplasm

9915:GABRE
gene id: 9915:GABRE
uniprot id: A0A6P5BMP5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:GSK3A
gene id: 9915:GSK3A
uniprot id: A0A6P5DA28
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

9915:LOC109575470
gene id: 9915:LOC109575470
uniprot id: A0A6P5DLF7
uniprot id: A0A6P5DMV3
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9915:SUMO1
gene id: 9915:SUMO1
uniprot id: A0A6P5D114
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

9915:HMGN4
gene id: 9915:HMGN4
uniprot id: A0A6P5DU04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9915:LOC109573099
gene id: 9915:LOC109573099
uniprot id: A0A6P5DE59
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:NPY
gene id: 9915:NPY
uniprot id: A0A6P5BDL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPY family.
messages: Secreted

9915:ENTPD3
gene id: 9915:ENTPD3
uniprot id: A0A6P5DR55
uniprot id: A0A6P5DUD4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9915:GRIK4
gene id: 9915:GRIK4
uniprot id: A0A6P5CY34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:IRF1
gene id: 9915:IRF1
uniprot id: A0A6P5C3H8
uniprot id: A0A6P5C4P4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:RAG2
gene id: 9915:RAG2
uniprot id: A0A6P5D1I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAG2 family.
messages: Nucleus

9915:CLIC5
gene id: 9915:CLIC5
uniprot id: A0A6P5DVW9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9915:SPEG
gene id: 9915:SPEG
uniprot id: A0A6P5D4B4
uniprot id: A0A6P5D4D0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9915:SLC8A2
gene id: 9915:SLC8A2
uniprot id: A0A6P5DC30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC8 subfamily.
messages: Cell membrane
messages: Membrane

9915:MLH3
gene id: 9915:MLH3
uniprot id: A0A6P5CGJ3
uniprot id: A0A6P5CH49
uniprot id: A0A6P5CIS0
uniprot id: A0A6P5CIS2
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9915:NDUFC1
gene id: 9915:NDUFC1
uniprot id: A0A6P5D3V8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFC1 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:CCSER2
gene id: 9915:CCSER2
uniprot id: A0A6P5AY28
uniprot id: A0A6P5BA01
uniprot id: A0A6P5BI04
uniprot id: A0A6P5BIC5
names: Similarity
messages: Belongs to the CCSER family.

9915:PPP1CA
gene id: 9915:PPP1CA
uniprot id: A0A6P5BK56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

9915:GPHB5
gene id: 9915:GPHB5
uniprot id: A0A6P5CEV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9915:MFSD6L
gene id: 9915:MFSD6L
uniprot id: A0A6P5DIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9915:VTI1B
gene id: 9915:VTI1B
uniprot id: A0A6P5CGR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9915:CTBS
gene id: 9915:CTBS
uniprot id: A0A6P5BQB2
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

9915:PIF1
gene id: 9915:PIF1
uniprot id: A0A6P5CCJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

9915:NDUFS8
gene id: 9915:NDUFS8
uniprot id: A0A6P5BCA2
names: Similarity
messages: Belongs to the complex I 23 kDa subunit family.

9915:LOC109568923
gene id: 9915:LOC109568923
uniprot id: A0A6P5CUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MOG
gene id: 9915:MOG
uniprot id: A0A6P5DSY9
uniprot id: A0A6P5DU21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Homodimer.
messages: Membrane
messages: Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication. Mediates homophilic cell-cell adhesion.

9915:HDAC3
gene id: 9915:HDAC3
uniprot id: A0A6P5C4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

9915:LOC109561318
gene id: 9915:LOC109561318
uniprot id: A0A6P5C0Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

9915:MYRF
gene id: 9915:MYRF
uniprot id: A0A6P5AZQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

9915:ZNF706
gene id: 9915:ZNF706
uniprot id: A0A6P5CUY6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:NDC80
gene id: 9915:NDC80
uniprot id: A0A6P5DW12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9915:C6H4orf22
gene id: 9915:C6H4orf22
uniprot id: A0A6P5BWI1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in spermatogenesis.
messages: Nucleus

9915:LOC109576521
gene id: 9915:LOC109576521
uniprot id: A0A6P5DQQ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:MTERF3
gene id: 9915:MTERF3
uniprot id: A0A6P5CXD0
names: Similarity
messages: Belongs to the mTERF family.

9915:SLC2A11
gene id: 9915:SLC2A11
uniprot id: A0A6P5D641
uniprot id: A0A6P5D895
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

9915:ST6GAL2
gene id: 9915:ST6GAL2
uniprot id: A0A6P5CJF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers sialic acid from the donor of substrate CMP-sialic acid to galactose containing acceptor substrates. Has alpha-2,6-sialyltransferase activity toward oligosaccharides that have the Gal-beta-1,4-GlcNAc sequence at the non-reducing end of their carbohydrate groups, but it has weak or no activities toward glycoproteins and glycolipids.

9915:FAM129A
gene id: 9915:FAM129A
uniprot id: A0A6P5D3L1
names: Similarity
messages: Belongs to the Niban family.

9915:LOC109553274
gene id: 9915:LOC109553274
uniprot id: A0A6P5B8D7
names: Similarity
messages: Belongs to the histone H3 family.

9915:LOC109568860
gene id: 9915:LOC109568860
uniprot id: A0A6P5CY78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569616
gene id: 9915:LOC109569616
uniprot id: A0A6P5CYE4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

9915:CNNM2
gene id: 9915:CNNM2
uniprot id: A0A6P5E1C7
uniprot id: A0A6P5E3X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

9915:LOC109576959
gene id: 9915:LOC109576959
uniprot id: A0A6P5DSC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPL7L1
gene id: 9915:RPL7L1
uniprot id: A0A6P5DTX0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

9915:HOXB3
gene id: 9915:HOXB3
uniprot id: A0A6P5DHD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:RBM17
gene id: 9915:RBM17
uniprot id: A0A6P5CSF5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

9915:EFNA3
gene id: 9915:EFNA3
uniprot id: A0A6P5AYB4
uniprot id: A0A6P5AYC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:ADGRF1
gene id: 9915:ADGRF1
uniprot id: A0A6P5DVG2
names: Subcellular Location Annotation
messages: Membrane

9915:TMEM165
gene id: 9915:TMEM165
uniprot id: A0A6P5BYT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

9915:ERLEC1
gene id: 9915:ERLEC1
uniprot id: A0A6P5CJL8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

9915:LOC109568890
gene id: 9915:LOC109568890
uniprot id: A0A6P5CUT7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569441
gene id: 9915:LOC109569441
uniprot id: A0A6P5CXB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:THBS2
gene id: 9915:THBS2
uniprot id: A0A6P5CC87
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ESR2
gene id: 9915:ESR2
uniprot id: A0A6P5CGY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9915:S100A16
gene id: 9915:S100A16
uniprot id: A0A6P5BDZ4
names: Similarity
messages: Belongs to the S-100 family.

9915:HSPA4
gene id: 9915:HSPA4
uniprot id: A0A6P5C4E3
uniprot id: A0A6P5C4H0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

9915:LOC109557256
gene id: 9915:LOC109557256
uniprot id: A0A6P5BAU7
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109554176
gene id: 9915:LOC109554176
uniprot id: A0A6P5ATE4
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:TMEM11
gene id: 9915:TMEM11
uniprot id: A0A6P5DEP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM11 family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Plays a role in mitochondrial morphogenesis.

9915:MUM1L1
gene id: 9915:MUM1L1
uniprot id: A0A6P5B4F8
names: Similarity
messages: Belongs to the PWWP3A family.

9915:HMCES
gene id: 9915:HMCES
uniprot id: A0A6P5DQ91
uniprot id: A0A6P5DRS2
uniprot id: A0A6P5DU84
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

9915:EIF2B5
gene id: 9915:EIF2B5
uniprot id: A0A6P5BQQ9
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

9915:SRP68
gene id: 9915:SRP68
uniprot id: A0A6P5DJK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

9915:TRIP10
gene id: 9915:TRIP10
uniprot id: A0A6P5C2V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNBP1 family.
messages: Cell membrane
messages: Lysosome
messages: Membrane
messages: cell cortex

9915:NAF1
gene id: 9915:NAF1
uniprot id: A0A6P5BWS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

9915:ONECUT2
gene id: 9915:ONECUT2
uniprot id: A0A6P5DUH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9915:GALR3
gene id: 9915:GALR3
uniprot id: A0A6P5BS24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:LOC109569473
gene id: 9915:LOC109569473
uniprot id: A0A6P5CXI7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPL23
gene id: 9915:RPL23
uniprot id: A0A6P5DIK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Component of the large ribosomal subunit.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

9915:DPH3
gene id: 9915:DPH3
uniprot id: A0A6P5C3R4
uniprot id: A0A6P5C3U0
uniprot id: A0A6P5C3W6
names: Similarity
messages: Belongs to the DPH3 family.

9915:PNPLA6
gene id: 9915:PNPLA6
uniprot id: A0A6P5C039
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LEPROTL1
gene id: 9915:LEPROTL1
uniprot id: A0A6P5BHE8
uniprot id: A0A6P5BHT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9915:NAPSA
gene id: 9915:NAPSA
uniprot id: A0A6P5D701
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:EDIL3
gene id: 9915:EDIL3
uniprot id: A0A6P5C5S2
uniprot id: A0A6P5C5V8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SOX6
gene id: 9915:SOX6
uniprot id: A0A6P5CVV8
uniprot id: A0A6P5CVX5
uniprot id: A0A6P5CVX9
uniprot id: A0A6P5CVY3
uniprot id: A0A6P5CWQ5
uniprot id: A0A6P5CWQ9
uniprot id: A0A6P5CWS2
uniprot id: A0A6P5CWS5
uniprot id: A0A6P5CWW9
uniprot id: A0A6P5CWX2
uniprot id: A0A6P5CYF1
uniprot id: A0A6P5CYG2
uniprot id: A0A6P5CYG4
uniprot id: A0A6P5CZ97
uniprot id: A0A6P5CZB6
names: Subcellular Location Annotation
messages: Nucleus

9915:TMEM138
gene id: 9915:TMEM138
uniprot id: A0A6P5ATS4
uniprot id: A0A6P5BC37
uniprot id: A0A6P5BJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

9915:TCN2
gene id: 9915:TCN2
uniprot id: A0A6P5D546
uniprot id: A0A6P5D8H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

9915:CWF19L1
gene id: 9915:CWF19L1
uniprot id: A0A6P5AP71
uniprot id: A0A6P5BGJ9
uniprot id: A0A6P5BH17
names: Similarity
messages: Belongs to the CWF19 family.

9915:LOC109558318
gene id: 9915:LOC109558318
uniprot id: A0A6P5BE23
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:KCNJ11
gene id: 9915:KCNJ11
uniprot id: A0A6P5D1W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

9915:LOC109560543
gene id: 9915:LOC109560543
uniprot id: A0A6P5BZI8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:FAM122A
gene id: 9915:FAM122A
uniprot id: A0A6P5C7N6
names: Similarity
messages: Belongs to the FAM122 family.

9915:STIM2
gene id: 9915:STIM2
uniprot id: A0A6P5BXR4
uniprot id: A0A6P5BY85
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109578184
gene id: 9915:LOC109578184
uniprot id: A0A6P5DWK1
names: Subcellular Location Annotation
messages: Nucleus

9915:CLDN4
gene id: 9915:CLDN4
uniprot id: A0A6P5E050
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:LOC109577705
gene id: 9915:LOC109577705
uniprot id: A0A6P5DY79
names: Similarity
messages: Belongs to the serpin family.

9915:CHRNA7
gene id: 9915:CHRNA7
uniprot id: A0A6P5DME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:PAN2
gene id: 9915:PAN2
uniprot id: A0A6P5BTM9
uniprot id: A0A6P5BTN0
uniprot id: A0A6P5BTN3
uniprot id: A0A6P5BTN4
uniprot id: A0A6P5BTP0
uniprot id: A0A6P5BTP1
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. Also acts as an important regulator of the HIF1A-mediated hypoxic response. Required for HIF1A mRNA stability independent of poly(A) tail length regulation.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts with ZFP36.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

9915:LOC109574043
gene id: 9915:LOC109574043
uniprot id: A0A6P5DHY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Core component of the MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase complex) complex, that regulates cytochrome c oxidase assembly. MITRAC complexes regulate both translation of mitochondrial encoded components and assembly of nuclear-encoded components imported in mitochondrion. Required for efficient translation of MT-CO1 and mitochondrial respiratory chain complex IV assembly.
messages: Membrane
messages: Required for assembly of cytochrome c oxidase (complex IV).

9915:BRS3
gene id: 9915:BRS3
uniprot id: A0A6P5BLA5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

9915:LOC109562654
gene id: 9915:LOC109562654
uniprot id: A0A6P5C6J2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:LOC109556339
gene id: 9915:LOC109556339
uniprot id: A0A6P5BPA1
uniprot id: A0A6P5BPC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRH/QCR6 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

9915:SEMA3A
gene id: 9915:SEMA3A
uniprot id: A0A6P5BRE6
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PRRX2
gene id: 9915:PRRX2
uniprot id: A0A6P5CHF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9915:B3GNT4
gene id: 9915:B3GNT4
uniprot id: A0A6P5D7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109569039
gene id: 9915:LOC109569039
uniprot id: A0A6P5CW21
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9915:RAB14
gene id: 9915:RAB14
uniprot id: A0A6P5CAA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

9915:LOC109569127
gene id: 9915:LOC109569127
uniprot id: A0A6P5CYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MICALL2
gene id: 9915:MICALL2
uniprot id: A0A6P5DZF3
names: Subcellular Location Annotation
messages: Membrane

9915:ZCCHC6
gene id: 9915:ZCCHC6
uniprot id: A0A6P5C8T2
uniprot id: A0A6P5C947
uniprot id: A0A6P5C953
uniprot id: A0A6P5C9A9
uniprot id: A0A6P5C9B5
uniprot id: A0A6P5C9C1
uniprot id: A0A6P5C9F2
uniprot id: A0A6P5CAB8
uniprot id: A0A6P5CAC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

9915:ESRP2
gene id: 9915:ESRP2
uniprot id: A0A6P5D7F9
uniprot id: A0A6P5D8X8
uniprot id: A0A6P5D9R0
uniprot id: A0A6P5DAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

9915:SDAD1
gene id: 9915:SDAD1
uniprot id: A0A6P5BWH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

9915:LOC109576707
gene id: 9915:LOC109576707
uniprot id: A0A6P5DSQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PDE8B
gene id: 9915:PDE8B
uniprot id: A0A6P5CD66
uniprot id: A0A6P5CED9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:LOC109564297
gene id: 9915:LOC109564297
uniprot id: A0A6P5CC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PKM
gene id: 9915:PKM
uniprot id: A0A6P5CD73
uniprot id: A0A6P5CFI7
names: Similarity
messages: Belongs to the pyruvate kinase family.

9915:PDGFRA
gene id: 9915:PDGFRA
uniprot id: A0A6P5BYE1
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

9915:PTPRK
gene id: 9915:PTPRK
uniprot id: A0A6P5CB28
uniprot id: A0A6P5CBH9
uniprot id: A0A6P5CBU7
uniprot id: A0A6P5CC77
uniprot id: A0A6P5CCZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

9915:KIF20A
gene id: 9915:KIF20A
uniprot id: A0A6P5C508
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:UNK
gene id: 9915:UNK
uniprot id: A0A6P5DEB5
uniprot id: A0A6P5DG08
uniprot id: A0A6P5DGQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

9915:LOC109560157
gene id: 9915:LOC109560157
uniprot id: A0A6P5BWM8
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

9915:SFTPC
gene id: 9915:SFTPC
uniprot id: A0A6P5C867
uniprot id: A0A6P5C8G3
uniprot id: A0A6P5C8N3
names: Function
names: Subcellular Location Annotation
messages: Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces.
messages: surface film

9915:IWS1
gene id: 9915:IWS1
uniprot id: A0A6P5CFJ9
uniprot id: A0A6P5CGR0
uniprot id: A0A6P5CIB4
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109564508
gene id: 9915:LOC109564508
uniprot id: A0A6P5CEL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GABRD
gene id: 9915:GABRD
uniprot id: A0A6P5D0Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:RPIA
gene id: 9915:RPIA
uniprot id: A0A6P5CIJ9
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

9915:KMT2C
gene id: 9915:KMT2C
uniprot id: A0A6P5BLF0
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109569341
gene id: 9915:LOC109569341
uniprot id: A0A6P5CZH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ADGRG3
gene id: 9915:ADGRG3
uniprot id: A0A6P5DFH6
names: Subcellular Location Annotation
messages: Membrane

9915:DCTN6
gene id: 9915:DCTN6
uniprot id: A0A6P5B9A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

9915:LOC109554195
gene id: 9915:LOC109554195
uniprot id: A0A6P5BBT9
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:PPARGC1A
gene id: 9915:PPARGC1A
uniprot id: A0A6P5BXN0
uniprot id: A0A6P5BXN4
uniprot id: A0A6P5BXP7
uniprot id: A0A6P5BYH2
names: Subcellular Location Annotation
messages: PML body

9915:FIGNL1
gene id: 9915:FIGNL1
uniprot id: A0A6P5BDP7
names: Similarity
messages: Belongs to the AAA ATPase family.

9915:WNT4
gene id: 9915:WNT4
uniprot id: A0A6P5DNZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:PRRC1
gene id: 9915:PRRC1
uniprot id: A0A6P5C4V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

9915:NOX4
gene id: 9915:NOX4
uniprot id: A0A6P5AVL2
uniprot id: A0A6P5BKN7
names: Subcellular Location Annotation
messages: Membrane

9915:SPIB
gene id: 9915:SPIB
uniprot id: A0A6P5D6S6
uniprot id: A0A6P5D8D1
uniprot id: A0A6P5D994
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:LOC109559512
gene id: 9915:LOC109559512
uniprot id: A0A6P5BUG3
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:PI4K2B
gene id: 9915:PI4K2B
uniprot id: A0A6P5BXP5
uniprot id: A0A6P5BXQ9
uniprot id: A0A6P5BY71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

9915:ITPRIPL2
gene id: 9915:ITPRIPL2
uniprot id: A0A6P5E2V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

9915:LOC109560197
gene id: 9915:LOC109560197
uniprot id: A0A6P5BWS3
names: Similarity
messages: Belongs to the FMO family.

9915:ITPR3
gene id: 9915:ITPR3
uniprot id: A0A6P5DS90
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9915:ASXL2
gene id: 9915:ASXL2
uniprot id: A0A6P5CJA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

9915:LOC109557116
gene id: 9915:LOC109557116
uniprot id: A0A6P5BQD2
names: Similarity
messages: Belongs to the LCE family.

9915:ITPR1
gene id: 9915:ITPR1
uniprot id: A0A6P5DT17
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the InsP3 receptor family.
messages: Endoplasmic reticulum membrane
messages: Homotetramer.
messages: Membrane
messages: Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium.
messages: The receptor contains a calcium channel in its C-terminal extremity. Its large N-terminal cytoplasmic region has the ligand-binding site in the N-terminus and modulatory sites in the middle portion immediately upstream of the channel region.

9915:PSME3
gene id: 9915:PSME3
uniprot id: A0A6P5DE04
names: Similarity
messages: Belongs to the PA28 family.

9915:PROS1
gene id: 9915:PROS1
uniprot id: A0A6P5C7J3
names: Caution
names: Function
messages: Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NEU3
gene id: 9915:NEU3
uniprot id: A0A6P5CYP0
uniprot id: A0A6P5CYX5
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

9915:GDA
gene id: 9915:GDA
uniprot id: A0A6P5C7S0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

9915:ORAI1
gene id: 9915:ORAI1
uniprot id: A0A6P5D3R6
uniprot id: A0A6P5D4A4
uniprot id: A0A6P5D657
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9915:RPE65
gene id: 9915:RPE65
uniprot id: A0A6P5BQ85
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9915:FGF20
gene id: 9915:FGF20
uniprot id: A0A6P5BH50
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9915:TNFSF13
gene id: 9915:TNFSF13
uniprot id: A0A6P5DE60
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:CD44
gene id: 9915:CD44
uniprot id: A0A6P5CY90
uniprot id: A0A6P5CY95
uniprot id: A0A6P5CYZ0
uniprot id: A0A6P5CZ84
uniprot id: A0A6P5D0Q6
uniprot id: A0A6P5D1Q6
uniprot id: A0A6P5D1R1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

9915:LOC109556908
gene id: 9915:LOC109556908
uniprot id: A0A6P5BJE0
names: Similarity
messages: Belongs to the TGF-beta family.

9915:GPR107
gene id: 9915:GPR107
uniprot id: A0A6P5CLQ3
names: Subcellular Location Annotation
messages: Membrane

9915:RAD52
gene id: 9915:RAD52
uniprot id: A0A6P5BVK9
uniprot id: A0A6P5BVL1
names: Similarity
messages: Belongs to the RAD52 family.

9915:LOC109558325
gene id: 9915:LOC109558325
uniprot id: A0A6P5BE27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

9915:ATP1B1
gene id: 9915:ATP1B1
uniprot id: A0A6P5D0E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Involved in cell adhesion and establishing epithelial cell polarity.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.
messages: sarcolemma

9915:MRPS18A
gene id: 9915:MRPS18A
uniprot id: A0A6P5DT60
uniprot id: A0A6P5DUJ6
names: Subcellular Location Annotation
messages: Mitochondrion

9915:PARVB
gene id: 9915:PARVB
uniprot id: A0A6P5BWP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: cytoskeleton

9915:ACER3
gene id: 9915:ACER3
uniprot id: A0A6P5CWM1
uniprot id: A0A6P5CXF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LYPLA1
gene id: 9915:LYPLA1
uniprot id: A0A6P5CUN0
uniprot id: A0A6P5CW51
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9915:LOC109557097
gene id: 9915:LOC109557097
uniprot id: A0A6P5BQC6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NDP
gene id: 9915:NDP
uniprot id: A0A6P5AZH0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:LOC109553864
gene id: 9915:LOC109553864
uniprot id: A0A6P5BII1
names: Similarity
names: Subunit
messages: Belongs to the SFTPD family.
messages: Oligomeric complex of 4 set of homotrimers.

9915:RFC5
gene id: 9915:RFC5
uniprot id: A0A6P5D3Q8
uniprot id: A0A6P5D4Y9
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9915:NBR1
gene id: 9915:NBR1
uniprot id: A0A6P5DEG4
uniprot id: A0A6P5DGU2
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

9915:LOC109576632
gene id: 9915:LOC109576632
uniprot id: A0A6P5DRI5
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:GTF2I
gene id: 9915:GTF2I
uniprot id: A0A6P5DXL0
uniprot id: A0A6P5DXL4
uniprot id: A0A6P5DYK4
uniprot id: A0A6P5E181
uniprot id: A0A6P5E1P9
uniprot id: A0A6P5E1Q1
names: Subcellular Location Annotation
messages: Nucleus

9915:CENPBD1
gene id: 9915:CENPBD1
uniprot id: A0A6P5DC79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9915:TM4SF20
gene id: 9915:TM4SF20
uniprot id: A0A6P5D7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9915:MRPL37
gene id: 9915:MRPL37
uniprot id: A0A6P5B7V7
uniprot id: A0A6P5BHX8
names: Subcellular Location Annotation
messages: Mitochondrion

9915:TP53
gene id: 9915:TP53
uniprot id: P67938
names: Cofactor
names: Disease Annotation
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of Lys-375 by CREBBP enhances transcriptional activity. Acetylation of Lys-375 by EP300. Deacetylation of Lys-375 by SIRT1 impairs its ability to induce proapoptotic program and modulate cell senescence. Deacetylation by SIRT2 impairs its ability to induce transcription activation in a AKT-dependent manner. Acetylation at Lys-374 increases stability. Deacetylation at Lys-374 by SIRT6 decreases its stability, thereby regulating cell senescence.
messages: Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 (By similarity). However, this activity is inhibited when the interaction with PPP1R13B/ASPP1 or TP53BP2/ASPP2 is displaced by PPP1R13L/iASPP (By similarity). In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seems to have an effect on cell-cycle regulation. Regulates the circadian clock by repressing CLOCK-ARNTL/BMAL1-mediated transcriptional activation of PER2.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Forms homodimers and homotetramers (By similarity). Binds DNA as a homotetramer. Interacts with AXIN1. Probably part of a complex consisting of TP53, HIPK2 and AXIN1. Interacts with histone acetyltransferases EP300 and methyltransferases HRMT1L2 and CARM1, and recruits them to promoters. Interacts (via C-terminus) with TAF1; when TAF1 is part of the TFIID complex. Interacts with ING4; this interaction may be indirect. Found in a complex with CABLES1 and TP73. Interacts with HIPK1, HIPK2, and TP53INP1. Interacts with WWOX. Interacts with USP7 and SYVN1. Interacts with HSP90AB1. Interacts with CHD8; leading to recruit histone H1 and prevent transactivation activity. Interacts with ARMC10, BANP, CDKN2AIP, NUAK1, STK11/LKB1, UHRF2 and E4F. Interacts with YWHAZ; the interaction enhances TP53 transcriptional activity. Phosphorylation of YWHAZ on 'Ser-58' inhibits this interaction. Interacts (via DNA-binding domain) with MAML1 (via N-terminus). Interacts with MKRN1. Interacts with PML (via C-terminus). Interacts with MDM2; leading to ubiquitination and proteasomal degradation of TP53. Directly interacts with FBXO42; leading to ubiquitination and degradation of TP53. Interacts (phosphorylated at Ser-15 by ATM) with the phosphatase PP2A-PPP2R5C holoenzyme; regulates stress-induced TP53-dependent inhibition of cell proliferation. Interacts with PPP2R2A. Interacts with AURKA, DAXX, BRD7 and TRIM24. Interacts (when monomethylated at Lys-375) with L3MBTL1. Interacts with GRK5. Binds to the CAK complex (CDK7, cyclin H and MAT1) in response to DNA damage. Interacts with CDK5 in neurons. Interacts with AURKB, SETD2, UHRF2 and NOC2L. Interacts (via N-terminus) with PTK2/FAK1; this promotes ubiquitination by MDM2. Interacts with PTK2B/PYK2; this promotes ubiquitination by MDM2. Interacts with PRKCG. Interacts with PPIF; the association implicates preferentially tetrameric TP53, is induced by oxidative stress and is impaired by cyclosporin A (CsA). Interacts with SNAI1; the interactio…
messages: Mitochondrion matrix
messages: Monomethylated at Lys-365 by SETD7, leading to stabilization and increased transcriptional activation. Monomethylated at Lys-363 by SMYD2, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity. Lys-365 monomethylation prevents interaction with SMYD2 and subsequent monomethylation at Lys-363. Dimethylated at Lys-366 by EHMT1 and EHMT2. Monomethylated at Lys-375 by KMT5A, promoting interaction with L3MBTL1 and leading to repress transcriptional activity. Demethylation of dimethylated Lys-363 by KDM1A prevents interaction with TP53BP1 and represses TP53-mediated transcriptional activation (By similarity). Monomethylated at Arg-326 and dimethylated at Arg-330 by PRMT5; methylation is increased after DNA damage and might possibly affect TP53 target gene specificity (By similarity).
messages: Nucleus
messages: PML body
messages: Phosphorylation on Ser residues mediates transcriptional activation. Phosphorylated on Thr-18 by VRK1, which may prevent the interaction with MDM2. Phosphorylated on Ser-20 by CHEK2 in response to DNA damage, which prevents ubiquitination by MDM2. Phosphorylated on Ser-20 by PLK3 in response to reactive oxygen species (ROS), promoting p53/TP53-mediated apoptosis. Phosphorylated on Ser-33 by CDK7 in a CAK complex in response to DNA damage. Phosphorylated by HIPK1. Phosphorylated on Ser-385 following UV but not gamma irradiation. Stabilized by CDK5-mediated phosphorylation in response to genotoxic and oxidative stresses at Ser-15 and Ser-33, leading to accumulation of p53/TP53, particularly in the nucleus, thus inducing the transactivation of p53/TP53 target genes. Phosphorylated at Ser-308 and Ser-385 by CDK2 in response to DNA-damage. Phosphorylated on Ser-385 following UV but not gamma irradiation (By similarity). Phosphorylation at Ser-15 is required for interaction with DDX3X and gamma-tubulin (By similarity).
messages: Sumoylated with SUMO1. Sumoylated at Lys-379 by UBC9 (By similarity).
messages: The [KR]-[STA]-K motif is specifically recognized by the SETD7 methyltransferase.
messages: Ubiquitinated by MDM2 and SYVN1, which leads to proteasomal degradation. Ubiquitinated by RFWD3, which works in cooperation with MDM2 and may catalyze the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. Ubiquitinated by MKRN1, which leads to proteasomal degradation. Deubiquitinated by USP10, leading to stabilize it. Ubiquitinated by TRIM24, RFFL, RNF34 and RNF125, which leads to proteasomal degradation. Ubiquitination by TOPORS induces degradation. Deubiquitination by USP7, leading to stabilize it. Ubiquitinated by COP1, which leads to proteasomal degradation (By similarity). Ubiquitination and subsequent proteasomal degradation is negatively regulated by CCAR2 (By similarity). Polyubiquitinated by C10orf90/FATS, polyubiquitination is 'Lys-48'-linkage independent and non-proteolytic, leading to TP53 stabilization (By similarity).
messages: centrosome
messages: p53 is found in increased amounts in a wide variety of transformed cells. p53 is frequently mutated or inactivated in many types of cancer.

9915:SENP5
gene id: 9915:SENP5
uniprot id: A0A6P5B368
uniprot id: A0A6P5BI26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C48 family.
messages: nucleolus

9915:AGRN
gene id: 9915:AGRN
uniprot id: A0A6P5D1F8
uniprot id: A0A6P5D213
uniprot id: A0A6P5D3D5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109560046
gene id: 9915:LOC109560046
uniprot id: A0A6P5BWS4
names: Subcellular Location Annotation
messages: Membrane

9915:ELOF1
gene id: 9915:ELOF1
uniprot id: A0A6P5C3L7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

9915:LOC109576628
gene id: 9915:LOC109576628
uniprot id: A0A6P5DSI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:BCR
gene id: 9915:BCR
uniprot id: A0A6P5D584
names: Subcellular Location Annotation
messages: Synapse
messages: axon
messages: dendritic spine

9915:NIPBL
gene id: 9915:NIPBL
uniprot id: A0A6P5DLV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

9915:HNF1A
gene id: 9915:HNF1A
uniprot id: A0A6P5D7K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

9915:INTS2
gene id: 9915:INTS2
uniprot id: A0A6P5DE79
names: Similarity
messages: Belongs to the Integrator subunit 2 family.

9915:FERMT1
gene id: 9915:FERMT1
uniprot id: A0A6P5CTN6
names: Similarity
messages: Belongs to the kindlin family.

9915:TCF7L2
gene id: 9915:TCF7L2
uniprot id: A0A6P5ANR7
uniprot id: A0A6P5ANS5
uniprot id: A0A6P5AVQ4
uniprot id: A0A6P5AVQ9
uniprot id: A0A6P5B7G9
uniprot id: A0A6P5B7H3
uniprot id: A0A6P5B7H7
uniprot id: A0A6P5B7I3
uniprot id: A0A6P5BGC2
uniprot id: A0A6P5BGC5
uniprot id: A0A6P5BGU7
uniprot id: A0A6P5BGV1
uniprot id: A0A6P5BGV4
names: Similarity
messages: Belongs to the TCF/LEF family.

9915:EXOSC9
gene id: 9915:EXOSC9
uniprot id: A0A6P5BWT2
uniprot id: A0A6P5BXH0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:CHCHD4
gene id: 9915:CHCHD4
uniprot id: A0A6P5DUB5
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

9915:LOC109569152
gene id: 9915:LOC109569152
uniprot id: A0A6P5CXY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109565473
gene id: 9915:LOC109565473
uniprot id: A0A6P5CJB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9915:CBLB
gene id: 9915:CBLB
uniprot id: A0A6P5CW60
uniprot id: A0A6P5CWC7
uniprot id: A0A6P5CWW1
uniprot id: A0A6P5CY03
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

9915:NXPE4
gene id: 9915:NXPE4
uniprot id: A0A6P5CZG7
names: Similarity
messages: Belongs to the NXPE family.

9915:PPP1R1C
gene id: 9915:PPP1R1C
uniprot id: A0A6P5CI69
uniprot id: A0A6P5CK98
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 1 family.

9915:MNAT1
gene id: 9915:MNAT1
uniprot id: A0A6P5CGI5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

9915:AREG
gene id: 9915:AREG
uniprot id: A0A6P5BWP7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TMEM126A
gene id: 9915:TMEM126A
uniprot id: A0A6P5B1E0
uniprot id: A0A6P5BDN5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569935
gene id: 9915:LOC109569935
uniprot id: A0A6P5CZW1
uniprot id: A0A6P5D2Q5
names: Similarity
messages: Belongs to the folate receptor family.

9915:LOC109576533
gene id: 9915:LOC109576533
uniprot id: A0A6P5DS75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DCLRE1A
gene id: 9915:DCLRE1A
uniprot id: A0A6P5E0Y7
uniprot id: A0A6P5E423
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

9915:MUS81
gene id: 9915:MUS81
uniprot id: A0A6P5B0U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

9915:VAT1L
gene id: 9915:VAT1L
uniprot id: A0A6P5DEZ5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9915:OLFML2B
gene id: 9915:OLFML2B
uniprot id: A0A6P5DW36
uniprot id: A0A6P5DW72
uniprot id: A0A6P5DZU1
uniprot id: A0A6P5E0B2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:GJC1
gene id: 9915:GJC1
uniprot id: A0A6P5DH61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins. Interacts with CNST.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:LOC109565594
gene id: 9915:LOC109565594
uniprot id: A0A6P5CHZ2
names: Similarity
messages: Belongs to the AAA ATPase family.

9915:GOT1L1
gene id: 9915:GOT1L1
uniprot id: A0A6P5AWL2
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

9915:CHMP5
gene id: 9915:CHMP5
uniprot id: A0A6P5C8Q7
names: Similarity
messages: Belongs to the SNF7 family.

9915:EBF3
gene id: 9915:EBF3
uniprot id: A0A6P5E0F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

9915:TATDN1
gene id: 9915:TATDN1
uniprot id: A0A6P5CTF9
uniprot id: A0A6P5CTS3
uniprot id: A0A6P5CVX7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

9915:NAPG
gene id: 9915:NAPG
uniprot id: A0A6P5DVG4
uniprot id: A0A6P5DZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9915:LOC109554268
gene id: 9915:LOC109554268
uniprot id: A0A6P5ATN7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RNF34
gene id: 9915:RNF34
uniprot id: A0A6P5D4Z8
uniprot id: A0A6P5D653
names: Subcellular Location Annotation
messages: Cell membrane

9915:LOC109556893
gene id: 9915:LOC109556893
uniprot id: A0A6P5BQ69
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SEC11A
gene id: 9915:SEC11A
uniprot id: A0A6P5DQ41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:EAF2
gene id: 9915:EAF2
uniprot id: A0A6P5AS87
names: Similarity
messages: Belongs to the EAF family.

9915:CAPN14
gene id: 9915:CAPN14
uniprot id: A0A6P5CH65
uniprot id: A0A6P5CK52
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LIPT1
gene id: 9915:LIPT1
uniprot id: A0A6P5CHA2
names: Similarity
messages: Belongs to the LplA family.

9915:ICOS
gene id: 9915:ICOS
uniprot id: A0A6P5CZE0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

9915:SQSTM1
gene id: 9915:SQSTM1
uniprot id: A0A6P5C1A3
names: Subcellular Location Annotation
messages: Lysosome
messages: autophagosome

9915:DPEP2
gene id: 9915:DPEP2
uniprot id: A0A6P5DC70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Homodimer; disulfide-linked.
messages: Membrane

9915:LOC109569229
gene id: 9915:LOC109569229
uniprot id: A0A6P5CZ43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109556080
gene id: 9915:LOC109556080
uniprot id: A0A6P5BNV4
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:DCBLD2
gene id: 9915:DCBLD2
uniprot id: A0A6P5CF67
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PUF60
gene id: 9915:PUF60
uniprot id: A0A6P5CSW8
uniprot id: A0A6P5CSX2
uniprot id: A0A6P5CU96
uniprot id: A0A6P5CVE6
uniprot id: A0A6P5CWG2
uniprot id: A0A6P5CWG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM half pint family.
messages: Nucleus

9915:MRPL1
gene id: 9915:MRPL1
uniprot id: A0A6P5BZT8
names: Subcellular Location Annotation
messages: Mitochondrion

9915:GABRR1
gene id: 9915:GABRR1
uniprot id: A0A6P5CC53
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:MSRB3
gene id: 9915:MSRB3
uniprot id: A0A6P5BT78
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

9915:NOP56
gene id: 9915:NOP56
uniprot id: A0A6P5CPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

9915:PIK3CA
gene id: 9915:PIK3CA
uniprot id: A0A6P5BD39
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9915:HDAC2
gene id: 9915:HDAC2
uniprot id: A0A6P5CA61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

9915:CPSF4L
gene id: 9915:CPSF4L
uniprot id: A0A6P5DEQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).
messages: Component of the cleavage and polyadenylation specificity factor (CPSF) complex.
messages: Nucleus

9915:NXPE2
gene id: 9915:NXPE2
uniprot id: A0A6P5D057
names: Similarity
messages: Belongs to the NXPE family.

9915:MYO15B
gene id: 9915:MYO15B
uniprot id: A0A6P5DEM3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9915:PMEPA1
gene id: 9915:PMEPA1
uniprot id: A0A6P5CPS2
uniprot id: A0A6P5CR26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9915:EMC7
gene id: 9915:EMC7
uniprot id: A0A6P5CFD5
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

9915:MARVELD3
gene id: 9915:MARVELD3
uniprot id: A0A6P5DAR1
uniprot id: A0A6P5DB01
names: Subcellular Location Annotation
messages: Membrane

9915:ATP13A4
gene id: 9915:ATP13A4
uniprot id: A0A6P5BPT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

9915:UBE2F
gene id: 9915:UBE2F
uniprot id: A0A6P5B502
uniprot id: A0A6P5BIZ6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:CFL2
gene id: 9915:CFL2
uniprot id: A0A6P5DLU9
names: Similarity
messages: Belongs to the actin-binding proteins ADF family.

9915:LOC109575526
gene id: 9915:LOC109575526
uniprot id: A0A6P5DLQ0
uniprot id: A0A6P5DMC5
uniprot id: A0A6P5DN47
uniprot id: A0A6P5DQ75
uniprot id: A0A6P5DQG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat EMAP family.
messages: cytoskeleton

9915:ANAPC13
gene id: 9915:ANAPC13
uniprot id: A0A6P5BWL7
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

9915:CA7
gene id: 9915:CA7
uniprot id: A0A6P5D9X3
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9915:UVSSA
gene id: 9915:UVSSA
uniprot id: A0A6P5BZK9
uniprot id: A0A6P5BZM8
uniprot id: A0A6P5BZW8
uniprot id: A0A6P5C0G6
names: Similarity
messages: Belongs to the UVSSA family.

9915:CCNI
gene id: 9915:CCNI
uniprot id: A0A6P5BZC6
names: Similarity
messages: Belongs to the cyclin family.

9915:TSPAN14
gene id: 9915:TSPAN14
uniprot id: A0A6P5BAL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:LOC109553468
gene id: 9915:LOC109553468
uniprot id: A0A6P5BHE9
uniprot id: A0A6P5BHT7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

9915:QPCTL
gene id: 9915:QPCTL
uniprot id: A0A6P5DES4
names: Similarity
messages: Belongs to the glutaminyl-peptide cyclotransferase family.

9915:CALCRL
gene id: 9915:CALCRL
uniprot id: A0A6P5CI97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

9915:RGS14
gene id: 9915:RGS14
uniprot id: A0A6P5C3W4
names: Subcellular Location Annotation
messages: dendrite

9915:LOC109555128
gene id: 9915:LOC109555128
uniprot id: A0A6P5B2U8
names: Similarity
messages: Belongs to the profilin family.

9915:KDELR1
gene id: 9915:KDELR1
uniprot id: A0A6P5DD80
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:CDK2
gene id: 9915:CDK2
uniprot id: A0A6P5BTS4
uniprot id: A0A6P5BTT4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:IDE
gene id: 9915:IDE
uniprot id: A0A6P5AV82
uniprot id: A0A6P5B6Z3
uniprot id: A0A6P5BG21
names: Similarity
messages: Belongs to the peptidase M16 family.

9915:LOC109576386
gene id: 9915:LOC109576386
uniprot id: A0A6P5DQR0
uniprot id: A0A6P5DU74
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

9915:LOC109570339
gene id: 9915:LOC109570339
uniprot id: A0A6P5D1M5
names: Similarity
messages: Belongs to the histone H2B family.

9915:LOC109568083
gene id: 9915:LOC109568083
uniprot id: A0A6P5CT67
names: Subcellular Location Annotation
messages: Nucleus

9915:DMRTC2
gene id: 9915:DMRTC2
uniprot id: A0A6P5D7N9
uniprot id: A0A6P5DB92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9915:MYH13
gene id: 9915:MYH13
uniprot id: A0A6P5DCL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9915:ARRDC4
gene id: 9915:ARRDC4
uniprot id: A0A6P5DQ29
names: Similarity
messages: Belongs to the arrestin family.

9915:LSS
gene id: 9915:LSS
uniprot id: A0A6P5C0X6
uniprot id: A0A6P5C181
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

9915:TMEM55B
gene id: 9915:TMEM55B
uniprot id: A0A6P5CE74
uniprot id: A0A6P5CFB5
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane
messages: phagosome membrane

9915:LOC109569361
gene id: 9915:LOC109569361
uniprot id: A0A6P5CW68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcitonin family.
messages: Secreted

9915:NAPEPLD
gene id: 9915:NAPEPLD
uniprot id: A0A6P5BQK2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPE-PLD family.
messages: Binds 2 zinc divalent cations per subunit.
messages: Homodimer. Bile acids promote the assembly of inactive monomers into an active dimer and enable catalysis.
messages: Nucleus envelope

9915:SSX2IP
gene id: 9915:SSX2IP
uniprot id: A0A6P5B2E0
uniprot id: A0A6P5B795
uniprot id: A0A6P5BHK8
uniprot id: A0A6P5BHK9
uniprot id: A0A6P5BNW2
uniprot id: A0A6P5BNY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

9915:TFDP2
gene id: 9915:TFDP2
uniprot id: A0A6P5BUV4
uniprot id: A0A6P5BUW8
uniprot id: A0A6P5BUX1
uniprot id: A0A6P5BUY2
uniprot id: A0A6P5BUY5
uniprot id: A0A6P5BV02
uniprot id: A0A6P5BV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:MX1
gene id: 9915:MX1
uniprot id: A0A6P5BYL9
uniprot id: A0A6P5BYP0
uniprot id: A0A6P5BYP3
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

9915:ITGB3
gene id: 9915:ITGB3
uniprot id: A0A6P5DIF2
uniprot id: A0A6P5DJH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

9915:NIF3L1
gene id: 9915:NIF3L1
uniprot id: A0A6P5CX89
uniprot id: A0A6P5CX97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
messages: Cytoplasm
messages: Homodimer. Interacts with COPS2. Interacts with THOC7.
messages: May function as a transcriptional corepressor through its interaction with COPS2, negatively regulating the expression of genes involved in neuronal differentiation.
messages: Nucleus

9915:CKM
gene id: 9915:CKM
uniprot id: A0A6P5DBL6
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

9915:LOC109563550
gene id: 9915:LOC109563550
uniprot id: A0A6P5CAT4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109562685
gene id: 9915:LOC109562685
uniprot id: A0A6P5C6Q2
names: Subcellular Location Annotation
messages: Nucleus

9915:CSTF3
gene id: 9915:CSTF3
uniprot id: A0A6P5CV63
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109564864
gene id: 9915:LOC109564864
uniprot id: A0A6P5CDR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:IL26
gene id: 9915:IL26
uniprot id: A0A6P5BS75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-10 family.
messages: Immune regulatory cytokine.
messages: Secreted

9915:CDK1
gene id: 9915:CDK1
uniprot id: A0A6P5BIQ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:CXCL9
gene id: 9915:CXCL9
uniprot id: A0A6P5BZ97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9915:MATN3
gene id: 9915:MATN3
uniprot id: A0A6P5CJJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109560354
gene id: 9915:LOC109560354
uniprot id: A0A6P5BY34
names: Similarity
messages: Belongs to the peptidase M17 family.

9915:GNPTAB
gene id: 9915:GNPTAB
uniprot id: A0A6P5BU36
uniprot id: A0A6P5BU53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

9915:STX19
gene id: 9915:STX19
uniprot id: A0A6P5C911
names: Similarity
messages: Belongs to the syntaxin family.

9915:AMOTL2
gene id: 9915:AMOTL2
uniprot id: A0A6P5BWR1
uniprot id: A0A6P5BWR2
names: Similarity
messages: Belongs to the angiomotin family.

9915:PITX1
gene id: 9915:PITX1
uniprot id: A0A6P5C4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9915:LOC109574986
gene id: 9915:LOC109574986
uniprot id: A0A6P5DNI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

9915:HOXA5
gene id: 9915:HOXA5
uniprot id: A0A6P5BQU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:ISYNA1
gene id: 9915:ISYNA1
uniprot id: A0A6P5C1Q0
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

9915:ANAPC16
gene id: 9915:ANAPC16
uniprot id: A0A6P5AXU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

9915:TNFRSF11B
gene id: 9915:TNFRSF11B
uniprot id: A0A6P5CVL9
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:VGLL3
gene id: 9915:VGLL3
uniprot id: A0A6P5C3G6
uniprot id: A0A6P5C3V3
uniprot id: A0A6P5C4B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9915:LOC109558484
gene id: 9915:LOC109558484
uniprot id: A0A6P5BAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SNX20
gene id: 9915:SNX20
uniprot id: A0A6P5DBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

9915:MYF5
gene id: 9915:MYF5
uniprot id: A0A6P5BSF5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation.
messages: Nucleus

9915:SCN5A
gene id: 9915:SCN5A
uniprot id: A0A6P5DUL5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9915:LOC109565815
gene id: 9915:LOC109565815
uniprot id: A0A6P5CK72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RECQL
gene id: 9915:RECQL
uniprot id: A0A6P5BS05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9915:GNB2
gene id: 9915:GNB2
uniprot id: A0A6P5DYP4
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9915:THOC2
gene id: 9915:THOC2
uniprot id: A0A6P5B383
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the THOC2 family.
messages: Component of the THO complex, which is composed of THOC1, THOC2, THOC3, THOC5, THOC6 and THOC7; together with at least ALYREF/THOC4, DDX39B, SARNP/CIP29 and CHTOP, THO forms the transcription/export (TREX) complex which seems to have a dynamic structure involving ATP-dependent remodeling. Interacts with THOC1, POLDIP3 and ZC3H11A.
messages: Nucleus

9915:HNMT
gene id: 9915:HNMT
uniprot id: A0A6P5CTC0
names: Function
names: Subunit
messages: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
messages: Monomer.

9915:LOC109569388
gene id: 9915:LOC109569388
uniprot id: A0A6P5CX78
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PRKAB2
gene id: 9915:PRKAB2
uniprot id: A0A6P5B5Y2
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9915:VPS45
gene id: 9915:VPS45
uniprot id: A0A6P5BMV3
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9915:LSM2
gene id: 9915:LSM2
uniprot id: A0A6P5DSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

9915:SLC35F1
gene id: 9915:SLC35F1
uniprot id: A0A6P5CAE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

9915:SHCBP1
gene id: 9915:SHCBP1
uniprot id: A0A6P5DBV2
names: Subcellular Location Annotation
messages: spindle

9915:LOC109566674
gene id: 9915:LOC109566674
uniprot id: A0A6P5CM82
uniprot id: A0A6P5CNE5
uniprot id: A0A6P5CPI2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:LOC109569190
gene id: 9915:LOC109569190
uniprot id: A0A6P5CWF0
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9915:TMSB4X
gene id: 9915:TMSB4X
uniprot id: A0A6P5BM52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9915:BHMT2
gene id: 9915:BHMT2
uniprot id: A0A6P5CD81
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

9915:PPP1R16B
gene id: 9915:PPP1R16B
uniprot id: A0A6P5CPH8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109571875
gene id: 9915:LOC109571875
uniprot id: A0A6P5D887
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:AP2M1
gene id: 9915:AP2M1
uniprot id: A0A6P5B792
uniprot id: A0A6P5BQQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cell membrane
messages: coated pit

9915:LIN7B
gene id: 9915:LIN7B
uniprot id: A0A6P5D6Y8
uniprot id: A0A6P5DAN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

9915:ANO10
gene id: 9915:ANO10
uniprot id: A0A6P5DSQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LIN52
gene id: 9915:LIN52
uniprot id: A0A6P5CFT9
names: Similarity
messages: Belongs to the lin-52 family.

9915:ACTL7B
gene id: 9915:ACTL7B
uniprot id: A0A6P5C6T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

9915:PAX5
gene id: 9915:PAX5
uniprot id: A0A6P5C8E7
uniprot id: A0A6P5C9E2
names: Subcellular Location Annotation
messages: Nucleus

9915:SUPT16H
gene id: 9915:SUPT16H
uniprot id: A0A6P5CG38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

9915:LOC109559507
gene id: 9915:LOC109559507
uniprot id: A0A6P5BUF9
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:RIPK3
gene id: 9915:RIPK3
uniprot id: A0A6P5CEF9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:LOC109570061
gene id: 9915:LOC109570061
uniprot id: A0A6P5D382
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558712
gene id: 9915:LOC109558712
uniprot id: A0A6P5BS54
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9915:LOC109571683
gene id: 9915:LOC109571683
uniprot id: A0A6P5D661
names: Similarity
messages: Belongs to the PDCD5 family.

9915:TMEM242
gene id: 9915:TMEM242
uniprot id: A0A6P5CDM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

9915:PRPSAP2
gene id: 9915:PRPSAP2
uniprot id: A0A6P5DHX7
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

9915:GDF5
gene id: 9915:GDF5
uniprot id: A0A6P5CS19
names: Similarity
messages: Belongs to the TGF-beta family.

9915:ADAM12
gene id: 9915:ADAM12
uniprot id: A0A6P5AVW9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TCTN2
gene id: 9915:TCTN2
uniprot id: A0A6P5D5X9
uniprot id: A0A6P5D9C8
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

9915:SLC8B1
gene id: 9915:SLC8B1
uniprot id: A0A6P5D433
uniprot id: A0A6P5D4K6
uniprot id: A0A6P5D7X1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109562948
gene id: 9915:LOC109562948
uniprot id: A0A6P5C7I7
uniprot id: A0A6P5C7P6
uniprot id: A0A6P5C7Q8
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109570000
gene id: 9915:LOC109570000
uniprot id: A0A6P5D047
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NELFCD
gene id: 9915:NELFCD
uniprot id: A0A6P5CNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

9915:MAT1A
gene id: 9915:MAT1A
uniprot id: A0A6P5BAR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

9915:PTCH2
gene id: 9915:PTCH2
uniprot id: A0A6P5B3P6
uniprot id: A0A6P5B3Q3
uniprot id: A0A6P5B8D2
uniprot id: A0A6P5BIA9
uniprot id: A0A6P5BIB1
uniprot id: A0A6P5BPC1
uniprot id: A0A6P5BPE5
uniprot id: A0A6P5BPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9915:MIEF1
gene id: 9915:MIEF1
uniprot id: A0A6P5BVY5
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9915:PPARG
gene id: 9915:PPARG
uniprot id: A0A6P5DQ77
uniprot id: A0A6P5DU68
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

9915:ATP5J
gene id: 9915:ATP5J
uniprot id: A0A6P5BNI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9915:LOC109566507
gene id: 9915:LOC109566507
uniprot id: A0A6P5CLX0
uniprot id: A0A6P5CMM0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Component of a complex at least composed of URM1, CTU2/NCS2 and CTU1/ATPBD3.
messages: Cytoplasm

9915:HOMER1
gene id: 9915:HOMER1
uniprot id: A0A6P5CDZ9
uniprot id: A0A6P5CF38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Homer family.
messages: Cytoplasm
messages: Postsynaptic density
messages: Synapse

9915:ASAH1
gene id: 9915:ASAH1
uniprot id: A0A6P5AQR4
uniprot id: A0A6P5BHX6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

9915:CTNNA2
gene id: 9915:CTNNA2
uniprot id: A0A6P5CK85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction
messages: axon
messages: cytoskeleton

9915:VLDLR
gene id: 9915:VLDLR
uniprot id: A0A6P5C7F0
uniprot id: A0A6P5C8V8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: clathrin-coated pit

9915:BRIX1
gene id: 9915:BRIX1
uniprot id: A0A6P5DJX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

9915:ADAMTS6
gene id: 9915:ADAMTS6
uniprot id: A0A6P5DK51
uniprot id: A0A6P5DKI0
uniprot id: A0A6P5DNL3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:SUPT3H
gene id: 9915:SUPT3H
uniprot id: A0A6P5DTC0
names: Subcellular Location Annotation
messages: Nucleus

9915:SLC9A9
gene id: 9915:SLC9A9
uniprot id: A0A6P5BUF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

9915:LOC109553578
gene id: 9915:LOC109553578
uniprot id: A0A6P5BHN5
names: Similarity
messages: Belongs to the histone H3 family.

9915:EFNA2
gene id: 9915:EFNA2
uniprot id: A0A6P5C4D5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:PPP1R7
gene id: 9915:PPP1R7
uniprot id: A0A6P5BJ15
names: Similarity
messages: Belongs to the SDS22 family.

9915:STEAP1
gene id: 9915:STEAP1
uniprot id: A0A6P5BQU3
names: Subcellular Location Annotation
messages: Membrane

9915:MFSD10
gene id: 9915:MFSD10
uniprot id: A0A6P5BZP7
uniprot id: A0A6P5BZQ0
uniprot id: A0A6P5C023
names: Subcellular Location Annotation
messages: Membrane

9915:SLU7
gene id: 9915:SLU7
uniprot id: A0A6P5C6Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

9915:CRTC2
gene id: 9915:CRTC2
uniprot id: A0A6P5AV18
uniprot id: A0A6P5BK82
uniprot id: A0A6P5BKB4
uniprot id: A0A6P5BKC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TORC family.
messages: Cytoplasm
messages: Nucleus

9915:KIF1BP
gene id: 9915:KIF1BP
uniprot id: A0A6P5AYR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

9915:PLCB3
gene id: 9915:PLCB3
uniprot id: A0A6P5B0K2
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9915:AMER1
gene id: 9915:AMER1
uniprot id: A0A6P5BM18
names: Similarity
messages: Belongs to the Amer family.

9915:DOCK8
gene id: 9915:DOCK8
uniprot id: A0A6P5C8W9
names: Similarity
messages: Belongs to the DOCK family.

9915:CNGA4
gene id: 9915:CNGA4
uniprot id: A0A6P5CZ15
names: Subcellular Location Annotation
messages: Membrane

9915:ZNF75A
gene id: 9915:ZNF75A
uniprot id: A0A6P5DXD6
names: Subcellular Location Annotation
messages: Nucleus

9915:GPX6
gene id: 9915:GPX6
uniprot id: A0A6P5DSL0
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:PRMT5
gene id: 9915:PRMT5
uniprot id: A0A6P5CE04
uniprot id: A0A6P5CF41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA).
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Nucleus

9915:GNG12
gene id: 9915:GNG12
uniprot id: A0A6P5B7J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:SMAD2
gene id: 9915:SMAD2
uniprot id: A0A6P5DZ60
names: Subcellular Location Annotation
messages: Nucleus

9915:TJAP1
gene id: 9915:TJAP1
uniprot id: A0A6P5DTP4
uniprot id: A0A6P5DTQ1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109578155
gene id: 9915:LOC109578155
uniprot id: A0A6P5DXK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RHCG
gene id: 9915:RHCG
uniprot id: A0A6P5DL73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9915:FN3KRP
gene id: 9915:FN3KRP
uniprot id: A0A6P5DHW3
uniprot id: A0A6P5DHW8
uniprot id: A0A6P5DKS5
names: Similarity
messages: Belongs to the fructosamine kinase family.

9915:PAX4
gene id: 9915:PAX4
uniprot id: A0A6P5BRG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

9915:ADSS
gene id: 9915:ADSS
uniprot id: A0A6P5D348
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

9915:LOC109562466
gene id: 9915:LOC109562466
uniprot id: A0A6P5C7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109554217
gene id: 9915:LOC109554217
uniprot id: A0A6P5ATI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109579150
gene id: 9915:LOC109579150
uniprot id: A0A6P5E1L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

9915:LOC109570227
gene id: 9915:LOC109570227
uniprot id: A0A6P5CZV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.
messages: Secreted

9915:NES
gene id: 9915:NES
uniprot id: A0A6P5B7X6
uniprot id: A0A6P5B7Y5
uniprot id: A0A6P5BH31
names: Similarity
messages: Belongs to the intermediate filament family.

9915:LOC109566120
gene id: 9915:LOC109566120
uniprot id: A0A6P5CJX4
uniprot id: A0A6P5CKP7
uniprot id: A0A6P5CKQ1
uniprot id: A0A6P5CLM8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:LOC109558732
gene id: 9915:LOC109558732
uniprot id: A0A6P5BMA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DPCD
gene id: 9915:DPCD
uniprot id: A0A6P5ANB0
names: Similarity
messages: Belongs to the DPCD family.

9915:LOC109561360
gene id: 9915:LOC109561360
uniprot id: A0A6P5C1F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:DR1
gene id: 9915:DR1
uniprot id: A0A6P5BNS1
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

9915:LOC109577300
gene id: 9915:LOC109577300
uniprot id: A0A6P5DTL5
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.

9915:LOC109575143
gene id: 9915:LOC109575143
uniprot id: A0A6P5DKW0
names: Subcellular Location Annotation
messages: Membrane

9915:NDFIP2
gene id: 9915:NDFIP2
uniprot id: A0A6P5CNY1
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9915:RPS6
gene id: 9915:RPS6
uniprot id: A0A6P5C7G5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

9915:SYNM
gene id: 9915:SYNM
uniprot id: A0A6P5DM07
uniprot id: A0A6P5DNT3
names: Similarity
messages: Belongs to the intermediate filament family.

9915:CHMP2B
gene id: 9915:CHMP2B
uniprot id: A0A6P5C601
names: Similarity
messages: Belongs to the SNF7 family.

9915:SEC61B
gene id: 9915:SEC61B
uniprot id: A0A6P5C839
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

9915:LOC109556330
gene id: 9915:LOC109556330
uniprot id: A0A6P5BPC0
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:CERS6
gene id: 9915:CERS6
uniprot id: A0A6P5DL08
names: Subcellular Location Annotation
messages: Membrane

9915:KIF3C
gene id: 9915:KIF3C
uniprot id: A0A6P5CKH4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:CLK3
gene id: 9915:CLK3
uniprot id: A0A6P5DME9
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:HDHD2
gene id: 9915:HDHD2
uniprot id: A0A6P5DV53
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

9915:NODAL
gene id: 9915:NODAL
uniprot id: A0A6P5AR33
names: Similarity
messages: Belongs to the TGF-beta family.

9915:GPR137
gene id: 9915:GPR137
uniprot id: A0A6P5BCP4
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

9915:ITIH3
gene id: 9915:ITIH3
uniprot id: A0A6P5DP78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9915:PTPN6
gene id: 9915:PTPN6
uniprot id: A0A6P5BC75
uniprot id: A0A6P5BMN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

9915:CFTR
gene id: 9915:CFTR
uniprot id: A0A6P5BL89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer; does not require oligomerization for channel activity. May form oligomers in the membrane (By similarity). Interacts with SLC26A3, SLC26A6 and SLC9A3R1 (By similarity). Interacts with SHANK2 (By similarity). Interacts with MYO6 (By similarity). Interacts (via C-terminus) with GOPC (via PDZ domain); this promotes CFTR internalization and thereby decreases channel activity. Interacts with SLC4A7 through SLC9A3R1. Found in a complex with MYO5B and RAB11A. Interacts with ANO1. Interacts with SLC26A8 (By similarity). Interacts with AHCYL1; the interaction increases CFTR activity (By similarity). Interacts with CSE1L (By similarity). The core-glycosylated form interacts with GORASP2 (via PDZ GRASP-type 1 domain) in respone to ER stress (By similarity). Interacts with MARCHF2; the interaction leads to CFTR ubiqtuitination and degradation.
messages: Recycling endosome membrane

9915:LOC109564526
gene id: 9915:LOC109564526
uniprot id: A0A6P5CDK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HGH1
gene id: 9915:HGH1
uniprot id: A0A6P5CVJ1
names: Similarity
messages: Belongs to the HGH1 family.

9915:PLAGL2
gene id: 9915:PLAGL2
uniprot id: A0A6P5CRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

9915:RFX2
gene id: 9915:RFX2
uniprot id: A0A6P5C2W8
uniprot id: A0A6P5C344
uniprot id: A0A6P5C430
names: Subcellular Location Annotation
messages: Nucleus

9915:GPR6
gene id: 9915:GPR6
uniprot id: A0A6P5C9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:CD164
gene id: 9915:CD164
uniprot id: A0A6P5CB18
uniprot id: A0A6P5CBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

9915:CRYL1
gene id: 9915:CRYL1
uniprot id: A0A6P5CMQ4
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

9915:BTG1
gene id: 9915:BTG1
uniprot id: A0A6P5BSG9
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

9915:SFXN2
gene id: 9915:SFXN2
uniprot id: A0A6P5AW95
uniprot id: A0A6P5BGQ7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9915:CARM1
gene id: 9915:CARM1
uniprot id: A0A6P5C2E4
uniprot id: A0A6P5C2J4
names: Subcellular Location Annotation
messages: Nucleus

9915:INSL3
gene id: 9915:INSL3
uniprot id: A0A6P5C1F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted
messages: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor.

9915:GABRA3
gene id: 9915:GABRA3
uniprot id: A0A6P5B519
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:TSPAN18
gene id: 9915:TSPAN18
uniprot id: A0A6P5D0Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:LOC109565628
gene id: 9915:LOC109565628
uniprot id: A0A6P5CGM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TDP1
gene id: 9915:TDP1
uniprot id: A0A6P5CJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

9915:LOC109554615
gene id: 9915:LOC109554615
uniprot id: A0A6P5BDU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

9915:DPYS
gene id: 9915:DPYS
uniprot id: A0A6P5CWF2
names: PTM
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.
messages: Carbamylation allows a single lysine to coordinate two divalent metal cations.

9915:LOC109574403
gene id: 9915:LOC109574403
uniprot id: A0A6P5DLK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:ITPRIPL1
gene id: 9915:ITPRIPL1
uniprot id: A0A6P5CH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Membrane

9915:LOC109565630
gene id: 9915:LOC109565630
uniprot id: A0A6P5CJL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CLIC6
gene id: 9915:CLIC6
uniprot id: A0A6P5BRT2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

9915:UBA7
gene id: 9915:UBA7
uniprot id: A0A6P5DPW6
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

9915:LOC109569104
gene id: 9915:LOC109569104
uniprot id: A0A6P5CXV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC13A1
gene id: 9915:SLC13A1
uniprot id: A0A6P5BDL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

9915:TMEM38B
gene id: 9915:TMEM38B
uniprot id: A0A6P5C9I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9915:CPNE9
gene id: 9915:CPNE9
uniprot id: A0A6P5DQ54
uniprot id: A0A6P5DTM2
names: Similarity
messages: Belongs to the copine family.

9915:LDLRAD1
gene id: 9915:LDLRAD1
uniprot id: A0A6P5B7X2
uniprot id: A0A6P5BHY9
uniprot id: A0A6P5BP52
uniprot id: A0A6P5BP78
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PAFAH1B1
gene id: 9915:PAFAH1B1
uniprot id: A0A6P5DHL0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with DCX, dynein, dynactin, IQGAP1, KATNB1, NDE1, NDEL1, NUDC and RSN. Interacts with DISC1, and this interaction is enhanced by NDEL1. Interacts with DAB1 when DAB1 is phosphorylated in response to RELN/reelin signaling. Component of cytosolic PAF-AH IB, which is composed of PAFAH1B1 (alpha), PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits. Trimer formation is not essential for the catalytic activity of the enzyme which is contributed solely by the PAFAH1B2 (beta) and PAFAH1B3 (gamma) subunits.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Nucleus membrane
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Neuronal migration involves a process called nucleokinesis, whereby migrating cells extend an anterior process into which the nucleus subsequently translocates. During nucleokinesis dynein at the nuclear surface may translocate the nucleus towards the centrosome by exerting force on centrosomal microtubules. Also required for proper activation of Rho GTPases and actin polymerization at the leading edge of locomoting cerebellar neurons and postmigratory hippocampal neurons in response to calcium influx triggered via NMDA receptors. May also play a role in other forms of cell locomotion including the migration of fibroblasts during wound healing. Non-catalytic subunit of an acetylhydrolase complex which inactivates platelet-activating factor (PAF) by removing the acetyl group at the SN-2 position.
messages: centrosome
messages: cytoskeleton
messages: spindle

9915:ATP1B4
gene id: 9915:ATP1B4
uniprot id: A0A6P5AX58
uniprot id: A0A6P5B2Y3
uniprot id: A0A6P5BEY7
uniprot id: A0A6P5BLI2
uniprot id: A0A6P5BLI5
uniprot id: A0A6P5BLL6
uniprot id: A0A6P5BLL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9915:A4GALT
gene id: 9915:A4GALT
uniprot id: A0A6P5BW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

9915:LOC109564723
gene id: 9915:LOC109564723
uniprot id: A0A6P5CDI0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9915:LOC109571874
gene id: 9915:LOC109571874
uniprot id: A0A6P5D955
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:STX18
gene id: 9915:STX18
uniprot id: A0A6P5BX38
names: Similarity
messages: Belongs to the syntaxin family.

9915:LOC109569251
gene id: 9915:LOC109569251
uniprot id: A0A6P5CZ67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109555778
gene id: 9915:LOC109555778
uniprot id: A0A6P5BN16
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:TAF7
gene id: 9915:TAF7
uniprot id: A0A6P5C4Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9915:DDC
gene id: 9915:DDC
uniprot id: A0A6P5BA16
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

9915:CDC42EP4
gene id: 9915:CDC42EP4
uniprot id: A0A6P5DGH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

9915:TWSG1
gene id: 9915:TWSG1
uniprot id: A0A6P5DVK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

9915:TAGLN3
gene id: 9915:TAGLN3
uniprot id: A0A6P5DAL4
names: Similarity
messages: Belongs to the calponin family.

9915:LOC109569232
gene id: 9915:LOC109569232
uniprot id: A0A6P5CVQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TMEM265
gene id: 9915:TMEM265
uniprot id: A0A6P5E0R9
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9915:CHST11
gene id: 9915:CHST11
uniprot id: A0A6P5BU66
uniprot id: A0A6P5BUA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:CCDC149
gene id: 9915:CCDC149
uniprot id: A0A6P5BXP4
uniprot id: A0A6P5BXQ6
names: Similarity
messages: Belongs to the CCDC149 family.

9915:NPM1
gene id: 9915:NPM1
uniprot id: A0A6P5DNH8
names: Similarity
messages: Belongs to the nucleoplasmin family.

9915:LOC109572735
gene id: 9915:LOC109572735
uniprot id: A0A6P5DAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

9915:LOC109558861
gene id: 9915:LOC109558861
uniprot id: A0A6P5BMI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:REXO2
gene id: 9915:REXO2
uniprot id: A0A6P5CZY2
names: Similarity
messages: Belongs to the oligoribonuclease family.

9915:JPH2
gene id: 9915:JPH2
uniprot id: A0A6P5CR40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:GAR1
gene id: 9915:GAR1
uniprot id: A0A6P5BX61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

9915:LOC109564480
gene id: 9915:LOC109564480
uniprot id: A0A6P5CDW4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SEMA5A
gene id: 9915:SEMA5A
uniprot id: A0A6P5DJ77
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:RIBC1
gene id: 9915:RIBC1
uniprot id: A0A6P5B448
uniprot id: A0A6P5BFT4
uniprot id: A0A6P5BM48
uniprot id: A0A6P5BM69
names: Similarity
messages: Belongs to the RIB43A family.

9915:FARSA
gene id: 9915:FARSA
uniprot id: A0A6P5C326
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

9915:ST6GALNAC2
gene id: 9915:ST6GALNAC2
uniprot id: A0A6P5DG63
uniprot id: A0A6P5DG69
uniprot id: A0A6P5DHQ9
uniprot id: A0A6P5DIK3
uniprot id: A0A6P5DJ34
uniprot id: A0A6P5DJ40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:FOXP2
gene id: 9915:FOXP2
uniprot id: A0A6P5BK34
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109571831
gene id: 9915:LOC109571831
uniprot id: A0A6P5DAB5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109573713
gene id: 9915:LOC109573713
uniprot id: A0A6P5DEI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9915:AGL
gene id: 9915:AGL
uniprot id: A0A6P5BNQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

9915:LOC109569393
gene id: 9915:LOC109569393
uniprot id: A0A6P5CYS6
names: Subcellular Location Annotation
messages: Membrane

9915:CHST14
gene id: 9915:CHST14
uniprot id: A0A6P5CF25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:AK4
gene id: 9915:AK4
uniprot id: A0A6P5BHT4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

9915:GALC
gene id: 9915:GALC
uniprot id: A0A6P5CHG8
uniprot id: A0A6P5CHV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

9915:PROK1
gene id: 9915:PROK1
uniprot id: A0A6P5B659
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

9915:AP4E1
gene id: 9915:AP4E1
uniprot id: A0A6P5CFF6
names: Function
names: Similarity
names: Subunit
messages: Adaptor protein complex 4 (AP-4) is a heterotetramer composed of two large adaptins, a medium adaptin and a small adaptin.
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin-associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.

9915:LOC109572080
gene id: 9915:LOC109572080
uniprot id: A0A6P5DAZ1
names: Subcellular Location Annotation
messages: Membrane

9915:SEC63
gene id: 9915:SEC63
uniprot id: A0A6P5CBT6
names: Subcellular Location Annotation
messages: Membrane

9915:CHM
gene id: 9915:CHM
uniprot id: A0A6P5BL54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

9915:UBE2R2
gene id: 9915:UBE2R2
uniprot id: A0A6P5C907
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:TRIM23
gene id: 9915:TRIM23
uniprot id: A0A6P5DMC2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9915:MMP20
gene id: 9915:MMP20
uniprot id: A0A6P5CYH5
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:SLC35C1
gene id: 9915:SLC35C1
uniprot id: A0A6P5CZ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

9915:EHD2
gene id: 9915:EHD2
uniprot id: A0A6P5DC23
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9915:KRT6A
gene id: 9915:KRT6A
uniprot id: A0A6P5BN38
names: Similarity
messages: Belongs to the intermediate filament family.

9915:MRPL42
gene id: 9915:MRPL42
uniprot id: A0A6P5BSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

9915:LOC109555764
gene id: 9915:LOC109555764
uniprot id: A0A6P5BN30
names: Similarity
messages: Belongs to the PRAME family.

9915:ALDH9A1
gene id: 9915:ALDH9A1
uniprot id: A0A6P5DVB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

9915:RPL11
gene id: 9915:RPL11
uniprot id: A0A6P5DFV2
uniprot id: A0A6P5DFW3
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

9915:LOC109560999
gene id: 9915:LOC109560999
uniprot id: A0A6P5C0L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FLI1
gene id: 9915:FLI1
uniprot id: A0A6P5B0P2
uniprot id: A0A6P5BK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:TLX3
gene id: 9915:TLX3
uniprot id: A0A6P5DJI9
names: Subcellular Location Annotation
messages: Nucleus

9915:ADGRG7
gene id: 9915:ADGRG7
uniprot id: A0A6P5CBB4
uniprot id: A0A6P5CDB3
names: Subcellular Location Annotation
messages: Membrane

9915:VRTN
gene id: 9915:VRTN
uniprot id: A0A6P5CDR2
names: Similarity
messages: Belongs to the vertnin family.

9915:FAM13A
gene id: 9915:FAM13A
uniprot id: A0A6P5BXH9
uniprot id: A0A6P5BXI1
uniprot id: A0A6P5BXI4
uniprot id: A0A6P5BXI5
uniprot id: A0A6P5BY11
uniprot id: A0A6P5BYC0
uniprot id: A0A6P5BYC4
names: Similarity
messages: Belongs to the FAM13 family.

9915:TIMM17B
gene id: 9915:TIMM17B
uniprot id: A0A6P5BFF1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

9915:LOC109568937
gene id: 9915:LOC109568937
uniprot id: A0A6P5CVW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TPMT
gene id: 9915:TPMT
uniprot id: A0A6P5DS19
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family.
messages: Cytoplasm
messages: Monomer.

9915:PRR15
gene id: 9915:PRR15
uniprot id: A0A6P5BQS4
names: Similarity
messages: Belongs to the PRR15 family.

9915:DNAH17
gene id: 9915:DNAH17
uniprot id: A0A6P5DHS2
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:LOC109563761
gene id: 9915:LOC109563761
uniprot id: A0A6P5CBC9
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9915:C19H17orf74
gene id: 9915:C19H17orf74
uniprot id: A0A6P5DI49
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109578860
gene id: 9915:LOC109578860
uniprot id: A0A6P5E3A7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CD53
gene id: 9915:CD53
uniprot id: A0A6P5B6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:LOC109556548
gene id: 9915:LOC109556548
uniprot id: A0A6P5B4T0
uniprot id: A0A6P5BPU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9915:RICTOR
gene id: 9915:RICTOR
uniprot id: A0A6P5DJW4
uniprot id: A0A6P5DJW9
uniprot id: A0A6P5DKV0
uniprot id: A0A6P5DMV5
uniprot id: A0A6P5DMW0
names: Similarity
messages: Belongs to the RICTOR family.

9915:C15H11orf70
gene id: 9915:C15H11orf70
uniprot id: A0A6P5D0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

9915:LOC109576814
gene id: 9915:LOC109576814
uniprot id: A0A6P5DVC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9915:TTC27
gene id: 9915:TTC27
uniprot id: A0A6P5CJX1
names: Similarity
messages: Belongs to the TTC27 family.

9915:LOC109554211
gene id: 9915:LOC109554211
uniprot id: A0A6P5BJK2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109562612
gene id: 9915:LOC109562612
uniprot id: A0A6P5C6J6
names: Similarity
messages: Belongs to the GrpE family.

9915:LOC109554025
gene id: 9915:LOC109554025
uniprot id: A0A6P5BJ82
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109556750
gene id: 9915:LOC109556750
uniprot id: A0A6P5BQ31
names: Similarity
messages: Belongs to the histone H2B family.

9915:GGNBP2
gene id: 9915:GGNBP2
uniprot id: A0A6P5DGG6
uniprot id: A0A6P5DGG9
uniprot id: A0A6P5DI00
uniprot id: A0A6P5DIW0
uniprot id: A0A6P5DJE2
names: Function
messages: May be involved in spermatogenesis.

9915:RITA1
gene id: 9915:RITA1
uniprot id: A0A6P5D4G1
uniprot id: A0A6P5D6S5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RITA family.
messages: Cytoplasm
messages: Interacts with RBPJ/RBPSUH.
messages: Nucleus
messages: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.

9915:LOC109559455
gene id: 9915:LOC109559455
uniprot id: A0A6P5BU86
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9915:LOC109553150
gene id: 9915:LOC109553150
uniprot id: A0A6P5BH52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9915:RCL1
gene id: 9915:RCL1
uniprot id: A0A6P5C7D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

9915:LOC109558521
gene id: 9915:LOC109558521
uniprot id: A0A6P5BS15
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:LOC109577707
gene id: 9915:LOC109577707
uniprot id: A0A6P5DUS6
names: Similarity
messages: Belongs to the serpin family.

9915:TNFSF8
gene id: 9915:TNFSF8
uniprot id: A0A6P5CAB7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:APCS
gene id: 9915:APCS
uniprot id: A0A6P5E0V8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9915:LEP
gene id: 9915:LEP
uniprot id: A0A6P5B844
uniprot id: A0A6P5BKJ7
names: Similarity
messages: Belongs to the leptin family.

9915:STAT6
gene id: 9915:STAT6
uniprot id: A0A6P5BTI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9915:FLNB
gene id: 9915:FLNB
uniprot id: A0A6P5DNA2
uniprot id: A0A6P5DNA7
uniprot id: A0A6P5DNW5
uniprot id: A0A6P5DPQ1
uniprot id: A0A6P5DRX0
uniprot id: A0A6P5DS64
uniprot id: A0A6P5DS72
names: Similarity
messages: Belongs to the filamin family.

9915:CDC45
gene id: 9915:CDC45
uniprot id: A0A6P5D3G4
uniprot id: A0A6P5D4N6
uniprot id: A0A6P5D5U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

9915:PLXNB3
gene id: 9915:PLXNB3
uniprot id: A0A6P5B223
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:BST1
gene id: 9915:BST1
uniprot id: A0A6P5BWI5
names: Similarity
messages: Belongs to the ADP-ribosyl cyclase family.

9915:LOC109555800
gene id: 9915:LOC109555800
uniprot id: A0A6P5DT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:SNX11
gene id: 9915:SNX11
uniprot id: A0A6P5DI18
uniprot id: A0A6P5DJE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

9915:SPDEF
gene id: 9915:SPDEF
uniprot id: A0A6P5DV82
uniprot id: A0A6P5DXR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:SELENOI
gene id: 9915:SELENOI
uniprot id: A0A6P5CMK9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9915:SLC14A2
gene id: 9915:SLC14A2
uniprot id: A0A6P5DUT0
uniprot id: A0A6P5DY83
uniprot id: A0A6P5DYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urea transporter family.
messages: Cell membrane
messages: Membrane

9915:TM4SF4
gene id: 9915:TM4SF4
uniprot id: A0A6P5BTK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9915:SOX1
gene id: 9915:SOX1
uniprot id: A0A6P5CMY7
names: Subcellular Location Annotation
messages: Nucleus

9915:NEMP2
gene id: 9915:NEMP2
uniprot id: A0A6P5CHL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

9915:SSR3
gene id: 9915:SSR3
uniprot id: A0A6P5BFF8
uniprot id: A0A6P5BN09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-gamma family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

9915:LOC109576951
gene id: 9915:LOC109576951
uniprot id: A0A6P5DSA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MBTPS2
gene id: 9915:MBTPS2
uniprot id: A0A6P5BLU4
names: Similarity
messages: Belongs to the peptidase M50A family.

9915:BZW2
gene id: 9915:BZW2
uniprot id: A0A6P5BAY6
names: Similarity
messages: Belongs to the BZW family.

9915:AFP
gene id: 9915:AFP
uniprot id: A0A6P5BZM4
names: Subcellular Location Annotation
messages: Secreted

9915:ACSM2B
gene id: 9915:ACSM2B
uniprot id: A0A6P5E019
uniprot id: A0A6P5E2L0
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:DLAT
gene id: 9915:DLAT
uniprot id: A0A6P5CY36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Mitochondrion matrix
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

9915:ANAPC10
gene id: 9915:ANAPC10
uniprot id: A0A6P5D5G7
names: Similarity
messages: Belongs to the APC10 family.

9915:CCDC90B
gene id: 9915:CCDC90B
uniprot id: A0A6P5BJX1
names: Similarity
messages: Belongs to the CCDC90 family.

9915:CDKAL1
gene id: 9915:CDKAL1
uniprot id: A0A6P5DSX3
uniprot id: A0A6P5DTA7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

9915:FASN
gene id: 9915:FASN
uniprot id: A0A6P5DCQ6
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

9915:GJA10
gene id: 9915:GJA10
uniprot id: A0A6P5CAW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:UXS1
gene id: 9915:UXS1
uniprot id: A0A6P5CIH4
uniprot id: A0A6P5CLN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

9915:NCL
gene id: 9915:NCL
uniprot id: A0A6P5DAP8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
messages: nucleolus

9915:LOC109562431
gene id: 9915:LOC109562431
uniprot id: A0A6P5C7F1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:DTNB
gene id: 9915:DTNB
uniprot id: A0A6P5CJB0
uniprot id: A0A6P5CKI0
uniprot id: A0A6P5CKY6
uniprot id: A0A6P5CLR4
uniprot id: A0A6P5CMM2
uniprot id: A0A6P5CMM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dystrophin family. Dystrobrevin subfamily.
messages: Cytoplasm

9915:LOC109561935
gene id: 9915:LOC109561935
uniprot id: A0A6P5C425
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. IRG family.

9915:NDRG2
gene id: 9915:NDRG2
uniprot id: A0A6P5CCE0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDRG family.
messages: Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation.
messages: Cytoplasm

9915:CASKIN1
gene id: 9915:CASKIN1
uniprot id: A0A6P5E0C7
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:LOC109562651
gene id: 9915:LOC109562651
uniprot id: A0A6P5C6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:TMEM120B
gene id: 9915:TMEM120B
uniprot id: A0A6P5D3A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM120 family.
messages: Membrane
messages: Nucleus inner membrane

9915:ANKRD34C
gene id: 9915:ANKRD34C
uniprot id: A0A6P5DPH4
names: Similarity
messages: Belongs to the ANKRD34 family.

9915:MAB21L2
gene id: 9915:MAB21L2
uniprot id: A0A6P5D7L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

9915:ATP9B
gene id: 9915:ATP9B
uniprot id: A0A6P5DUY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9915:FAM83C
gene id: 9915:FAM83C
uniprot id: A0A6P5CRV1
names: Similarity
messages: Belongs to the FAM83 family.

9915:THOP1
gene id: 9915:THOP1
uniprot id: A0A6P5C3D3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

9915:MTERF2
gene id: 9915:MTERF2
uniprot id: A0A6P5BUD2
names: Similarity
messages: Belongs to the mTERF family.

9915:LRP12
gene id: 9915:LRP12
uniprot id: A0A6P5CTL1
uniprot id: A0A6P5CX61
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109568869
gene id: 9915:LOC109568869
uniprot id: A0A6P5CY85
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NEURL2
gene id: 9915:NEURL2
uniprot id: A0A6P5CR90
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109558326
gene id: 9915:LOC109558326
uniprot id: A0A6P5BLT2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptotagmin family.
messages: Binds 3 Ca(2+) ions per subunit. The ions are bound to the C2 domains.
messages: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone.
messages: Membrane
messages: chromaffin granule membrane
messages: synaptic vesicle membrane

9915:KCNK13
gene id: 9915:KCNK13
uniprot id: A0A6P5CEH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9915:SLC39A13
gene id: 9915:SLC39A13
uniprot id: A0A6P5CXH9
uniprot id: A0A6P5CYD3
uniprot id: A0A6P5D005
uniprot id: A0A6P5D0V7
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109561755
gene id: 9915:LOC109561755
uniprot id: A0A6P5C3C3
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109568953
gene id: 9915:LOC109568953
uniprot id: A0A6P5CUZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPL9
gene id: 9915:RPL9
uniprot id: A0A6P5BYR1
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

9915:BCL2L13
gene id: 9915:BCL2L13
uniprot id: A0A6P5BM55
names: Similarity
messages: Belongs to the Bcl-2 family.

9915:TMOD1
gene id: 9915:TMOD1
uniprot id: A0A6P5C8H2
names: Subcellular Location Annotation
messages: cytoskeleton

9915:FBLN1
gene id: 9915:FBLN1
uniprot id: A0A6P5BW82
uniprot id: A0A6P5BWF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:USB1
gene id: 9915:USB1
uniprot id: A0A6P5DCL6
uniprot id: A0A6P5DCN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. USB1 family.
messages: Nucleus
messages: Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA 3' end-terminated with a 2',3'-cyclic phosphate.

9915:SLC16A4
gene id: 9915:SLC16A4
uniprot id: A0A6P5BNH0
names: Subcellular Location Annotation
messages: Membrane

9915:GDF9
gene id: 9915:GDF9
uniprot id: A0A6P5C4D3
uniprot id: A0A6P5C5S0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer or heterodimer (Potential). But, in contrast to other members of this family, cannot be disulfide-linked.
messages: Secreted

9915:LOC109560460
gene id: 9915:LOC109560460
uniprot id: A0A6P5BYA3
uniprot id: A0A6P5BYB7
names: Similarity
messages: Belongs to the SH3BGR family.

9915:LOC109569749
gene id: 9915:LOC109569749
uniprot id: A0A6P5CZ28
names: Similarity
messages: Belongs to the HPF1 family.

9915:LPAR3
gene id: 9915:LPAR3
uniprot id: A0A6P5B2C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109563964
gene id: 9915:LOC109563964
uniprot id: A0A6P5CBM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC22A3
gene id: 9915:SLC22A3
uniprot id: A0A6P5CAK6
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9915:FZD1
gene id: 9915:FZD1
uniprot id: A0A6P5BA39
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109556967
gene id: 9915:LOC109556967
uniprot id: A0A6P5BJH2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PMVK
gene id: 9915:PMVK
uniprot id: A0A6P5AT01
uniprot id: A0A6P5BJ63
names: Subcellular Location Annotation
messages: cytosol

9915:INO80C
gene id: 9915:INO80C
uniprot id: A0A6P5DVV7
uniprot id: A0A6P5DZX8
names: Subcellular Location Annotation
messages: Nucleus

9915:LDHAL6B
gene id: 9915:LDHAL6B
uniprot id: A0A6P5CBP8
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

9915:LOC109559508
gene id: 9915:LOC109559508
uniprot id: A0A6P5BUF7
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:LOC109576641
gene id: 9915:LOC109576641
uniprot id: A0A6P5DV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:PSMA3
gene id: 9915:PSMA3
uniprot id: A0A6P5CGF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9915:ADSL
gene id: 9915:ADSL
uniprot id: A0A6P5BVY3
uniprot id: A0A6P5BWA1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

9915:LOC109579033
gene id: 9915:LOC109579033
uniprot id: A0A6P5E0F0
names: Caution
names: Similarity
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:OSBP
gene id: 9915:OSBP
uniprot id: A0A6P5D0V3
names: Similarity
messages: Belongs to the OSBP family.

9915:GPC4
gene id: 9915:GPC4
uniprot id: A0A6P5BFZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

9915:SNX7
gene id: 9915:SNX7
uniprot id: A0A6P5B1U2
uniprot id: A0A6P5BNR1
names: Similarity
messages: Belongs to the sorting nexin family.

9915:E2F3
gene id: 9915:E2F3
uniprot id: A0A6P5DTT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

9915:LOC109571696
gene id: 9915:LOC109571696
uniprot id: A0A6P5D9Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:ZNF330
gene id: 9915:ZNF330
uniprot id: A0A6P5D6V3
uniprot id: A0A6P5D970
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

9915:LOC109556228
gene id: 9915:LOC109556228
uniprot id: A0A6P5B7R5
uniprot id: A0A6P5BHV6
uniprot id: A0A6P5BP23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9915:TMTC1
gene id: 9915:TMTC1
uniprot id: A0A6P5BUP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9915:LOC109558820
gene id: 9915:LOC109558820
uniprot id: A0A6P5BMF9
names: Subcellular Location Annotation
messages: Membrane

9915:RBX1
gene id: 9915:RBX1
uniprot id: A0A6P5BVZ8
names: Similarity
messages: Belongs to the RING-box family.

9915:CAPN11
gene id: 9915:CAPN11
uniprot id: A0A6P5DRA3
names: Similarity
messages: Belongs to the peptidase C2 family.

9915:ZKSCAN2
gene id: 9915:ZKSCAN2
uniprot id: A0A6P5E369
names: Function
names: Subcellular Location Annotation
messages: May be involved in transcriptional regulation.
messages: Nucleus

9915:LOC109555733
gene id: 9915:LOC109555733
uniprot id: A0A6P5BN23
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:SLC35A3
gene id: 9915:SLC35A3
uniprot id: A0A6P5B6R6
uniprot id: A0A6P5BHA7
uniprot id: A0A6P5BNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9915:ACAD9
gene id: 9915:ACAD9
uniprot id: A0A6P5DPX0
uniprot id: A0A6P5DTZ1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9915:LOC109569080
gene id: 9915:LOC109569080
uniprot id: A0A6P5CXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ATP6V1G2
gene id: 9915:ATP6V1G2
uniprot id: A0A6P5DWJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9915:LOC109556803
gene id: 9915:LOC109556803
uniprot id: A0A6P5B5M0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569216
gene id: 9915:LOC109569216
uniprot id: A0A6P5CY56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NCF2
gene id: 9915:NCF2
uniprot id: A0A6P5D0S5
uniprot id: A0A6P5D4H6
names: Similarity
messages: Belongs to the NCF2/NOXA1 family.

9915:MDH1
gene id: 9915:MDH1
uniprot id: A0A6P5CJX3
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Homodimer.

9915:GAL3ST3
gene id: 9915:GAL3ST3
uniprot id: A0A6P5BJF4
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9915:SLC4A9
gene id: 9915:SLC4A9
uniprot id: A0A6P5C4S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

9915:RSBN1L
gene id: 9915:RSBN1L
uniprot id: A0A6P5BB94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

9915:USP27X
gene id: 9915:USP27X
uniprot id: A0A6P5AWC2
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9915:ARPC1B
gene id: 9915:ARPC1B
uniprot id: A0A6P5CM50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

9915:WDFY2
gene id: 9915:WDFY2
uniprot id: A0A6P5CNT3
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

9915:TPI1
gene id: 9915:TPI1
uniprot id: A0A6P5BSD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

9915:ESYT3
gene id: 9915:ESYT3
uniprot id: A0A6P5C9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109576914
gene id: 9915:LOC109576914
uniprot id: A0A6P5DT92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:CSGALNACT1
gene id: 9915:CSGALNACT1
uniprot id: A0A6P5AQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9915:PRR5L
gene id: 9915:PRR5L
uniprot id: A0A6P5CYR2
names: Similarity
messages: Belongs to the PROTOR family.

9915:LOC109564501
gene id: 9915:LOC109564501
uniprot id: A0A6P5CCG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576389
gene id: 9915:LOC109576389
uniprot id: A0A6P5DQR0
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

9915:SLC43A1
gene id: 9915:SLC43A1
uniprot id: A0A6P5D1M2
names: Subcellular Location Annotation
messages: Membrane

9915:SMIM24
gene id: 9915:SMIM24
uniprot id: A0A6P5C376
names: Subcellular Location Annotation
messages: Membrane

9915:CHRNA2
gene id: 9915:CHRNA2
uniprot id: A0A6P5C8Y4
uniprot id: A0A6P5C908
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:SLC30A6
gene id: 9915:SLC30A6
uniprot id: A0A6P5CIQ5
uniprot id: A0A6P5CJX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9915:AQP10
gene id: 9915:AQP10
uniprot id: A0A6P5BQ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9915:LOC109557362
gene id: 9915:LOC109557362
uniprot id: A0A6P5B6Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

9915:ATP8B4
gene id: 9915:ATP8B4
uniprot id: A0A6P5CC94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9915:MRPL49
gene id: 9915:MRPL49
uniprot id: A0A6P5BCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

9915:CA6
gene id: 9915:CA6
uniprot id: A0A6P5D2K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide. Its role in saliva is unknown.
messages: Secreted

9915:PRKACA
gene id: 9915:PRKACA
uniprot id: A0A6P5C1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.
messages: Nucleus

9915:LOC109575173
gene id: 9915:LOC109575173
uniprot id: A0A6P5DLR7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:POU3F1
gene id: 9915:POU3F1
uniprot id: A0A6P5BAC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9915:SLC22A5
gene id: 9915:SLC22A5
uniprot id: A0A6P5C3P1
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

9915:UPF2
gene id: 9915:UPF2
uniprot id: A0A6P5CQX8
names: Subcellular Location Annotation
messages: Cytoplasm

9915:ZDHHC13
gene id: 9915:ZDHHC13
uniprot id: A0A6P5AV55
uniprot id: A0A6P5BKE9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:KRT79
gene id: 9915:KRT79
uniprot id: A0A6P5BD34
names: Similarity
messages: Belongs to the intermediate filament family.

9915:MINPP1
gene id: 9915:MINPP1
uniprot id: A0A6P5AP42
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

9915:PROSC
gene id: 9915:PROSC
uniprot id: A0A6P5AXG1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

9915:LOC109564523
gene id: 9915:LOC109564523
uniprot id: A0A6P5CCI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TMEM263
gene id: 9915:TMEM263
uniprot id: A0A6P5BU98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

9915:FOXP1
gene id: 9915:FOXP1
uniprot id: A0A6P5DNN2
uniprot id: A0A6P5DNN7
uniprot id: A0A6P5DP85
uniprot id: A0A6P5DSC2
uniprot id: A0A6P5DSC5
names: Subcellular Location Annotation
messages: Nucleus

9915:ESRRA
gene id: 9915:ESRRA
uniprot id: A0A6P5BJY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9915:ARRDC5
gene id: 9915:ARRDC5
uniprot id: A0A6P5C378
names: Similarity
messages: Belongs to the arrestin family.

9915:LOC109554104
gene id: 9915:LOC109554104
uniprot id: A0A6P5AT95
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:GRK5
gene id: 9915:GRK5
uniprot id: A0A6P5BGB6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9915:LIM2
gene id: 9915:LIM2
uniprot id: A0A6P5D7N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Present in the thicker 16-17 nm junctions of mammalian lens fiber cells, where it may contribute to cell junctional organization. Acts as a receptor for calmodulin. May play an important role in both lens development and cataractogenesis.

9915:MCM10
gene id: 9915:MCM10
uniprot id: A0A6P5CRB1
uniprot id: A0A6P5CSG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

9915:IRX6
gene id: 9915:IRX6
uniprot id: A0A6P5DEL9
names: Subcellular Location Annotation
messages: Nucleus

9915:TBR1
gene id: 9915:TBR1
uniprot id: A0A6P5DS57
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:GCNT7
gene id: 9915:GCNT7
uniprot id: A0A6P5CQC0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9915:TMEM256
gene id: 9915:TMEM256
uniprot id: A0A6P5DIR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM256 family.
messages: Membrane

9915:HOXC13
gene id: 9915:HOXC13
uniprot id: A0A6P5BS42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:NMUR2
gene id: 9915:NMUR2
uniprot id: A0A6P5C167
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

9915:LOC109568972
gene id: 9915:LOC109568972
uniprot id: A0A6P5CW70
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LYPD2
gene id: 9915:LYPD2
uniprot id: A0A6P5CU70
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:ZFPL1
gene id: 9915:ZFPL1
uniprot id: A0A6P5B0J7
uniprot id: A0A6P5BK29
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZFPL1 family.
messages: Interacts with GOLGA2/GM130.
messages: Membrane
messages: Required for cis-Golgi integrity and efficient ER to Golgi transport.
messages: The B box-type and RING-type zinc fingers although degenerate play a central role in function of the protein.
messages: cis-Golgi network membrane

9915:LOC109556325
gene id: 9915:LOC109556325
uniprot id: A0A6P5B3G9
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:LOC109564797
gene id: 9915:LOC109564797
uniprot id: A0A6P5CEM6
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SULF2
gene id: 9915:SULF2
uniprot id: A0A6P5CPV7
uniprot id: A0A6P5CQY7
uniprot id: A0A6P5CRC9
uniprot id: A0A6P5CS71
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:LOC109558742
gene id: 9915:LOC109558742
uniprot id: A0A6P5BMB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BSG
gene id: 9915:BSG
uniprot id: A0A6P5C4K4
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Lateral cell membrane

9915:LOC109568982
gene id: 9915:LOC109568982
uniprot id: A0A6P5CXL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109573434
gene id: 9915:LOC109573434
uniprot id: A0A6P5DD98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

9915:MAML3
gene id: 9915:MAML3
uniprot id: A0A6P5D8S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

9915:IGFBP2
gene id: 9915:IGFBP2
uniprot id: A0A6P5DRA5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SDCCAG3
gene id: 9915:SDCCAG3
uniprot id: A0A6P5CP62
names: Similarity
messages: Belongs to the ENTR1 family.

9915:ITGA7
gene id: 9915:ITGA7
uniprot id: A0A6P5BTX0
uniprot id: A0A6P5BTX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:CHMP7
gene id: 9915:CHMP7
uniprot id: A0A6P5C8K4
names: Similarity
messages: Belongs to the SNF7 family.

9915:ABCD3
gene id: 9915:ABCD3
uniprot id: A0A6P5B6U6
uniprot id: A0A6P5BHC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCD family. Peroxisomal fatty acyl CoA transporter (TC 3.A.1.203) subfamily.
messages: Membrane
messages: Peroxisome membrane

9915:STX11
gene id: 9915:STX11
uniprot id: A0A6P5CCR0
names: Similarity
messages: Belongs to the syntaxin family.

9915:LOC109577131
gene id: 9915:LOC109577131
uniprot id: A0A6P5DU65
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:CACHD1
gene id: 9915:CACHD1
uniprot id: A0A6P5BP09
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9915:HOXB6
gene id: 9915:HOXB6
uniprot id: A0A6P5DIQ2
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109564098
gene id: 9915:LOC109564098
uniprot id: A0A6P5CBS3
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9915:SLC6A2
gene id: 9915:SLC6A2
uniprot id: A0A6P5DC13
uniprot id: A0A6P5DF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9915:NIP7
gene id: 9915:NIP7
uniprot id: A0A6P5DAP6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

9915:CHSY1
gene id: 9915:CHSY1
uniprot id: A0A6P5DKD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

9915:MED19
gene id: 9915:MED19
uniprot id: A0A6P5D062
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:C6H4orf32
gene id: 9915:C6H4orf32
uniprot id: A0A6P5BX25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM241 family.
messages: Membrane

9915:LOC109558959
gene id: 9915:LOC109558959
uniprot id: A0A6P5BSG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Secreted
messages: filopodium
messages: lamellipodium

9915:DNAH2
gene id: 9915:DNAH2
uniprot id: A0A6P5DHZ2
uniprot id: A0A6P5DI44
uniprot id: A0A6P5DI51
uniprot id: A0A6P5DKH0
uniprot id: A0A6P5DKY7
uniprot id: A0A6P5DKZ4
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:GADD45G
gene id: 9915:GADD45G
uniprot id: A0A6P5C916
names: Similarity
messages: Belongs to the GADD45 family.

9915:RPS9
gene id: 9915:RPS9
uniprot id: A0A6P5D7F1
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs.

9915:DIP2C
gene id: 9915:DIP2C
uniprot id: A0A6P5CSA5
uniprot id: A0A6P5CT96
names: Similarity
messages: Belongs to the DIP2 family.

9915:HMGCL
gene id: 9915:HMGCL
uniprot id: A0A6P5DFJ5
uniprot id: A0A6P5DFK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

9915:CXCL10
gene id: 9915:CXCL10
uniprot id: A0A6P5BYV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9915:MCOLN1
gene id: 9915:MCOLN1
uniprot id: A0A6P5C2F6
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

9915:LCORL
gene id: 9915:LCORL
uniprot id: A0A6P5BXK9
names: Subcellular Location Annotation
messages: Nucleus

9915:CSPG4
gene id: 9915:CSPG4
uniprot id: A0A6P5DPP9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CLK2
gene id: 9915:CLK2
uniprot id: A0A6P5AR62
uniprot id: A0A6P5B9N2
uniprot id: A0A6P5BHR8
uniprot id: A0A6P5BI61
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:APH1B
gene id: 9915:APH1B
uniprot id: A0A6P5CEF6
uniprot id: A0A6P5CF24
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

9915:TLR9
gene id: 9915:TLR9
uniprot id: M1LH26
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Endosome
messages: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production.
messages: Lysosome
messages: Membrane
messages: phagosome

9915:TMEFF1
gene id: 9915:TMEFF1
uniprot id: A0A6P5C9R8
uniprot id: A0A6P5C9S9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109557834
gene id: 9915:LOC109557834
uniprot id: A0A6P5BRD5
names: Similarity
messages: Belongs to the ATPase C chain family.

9915:COMT
gene id: 9915:COMT
uniprot id: A0A6P5D5J4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
messages: Cell membrane

9915:MORF4L2
gene id: 9915:MORF4L2
uniprot id: A0A6P5AXA3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the NuA4 histone acetyltransferase complex which contains the catalytic subunit KAT5/TIP60 and the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, DMAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41 and VPS72/YL1. The NuA4 complex interacts with MYC and the adenovirus E1A protein. MORF4L1 may also participate in the formation of NuA4 related complexes which lack the KAT5/TIP60 catalytic subunit, but which include the SWI/SNF related protein SRCAP. Component of the MSIN3A histone deacetylase complex, which includes SIN3A, HDAC2, ARID4B, MORF4L1, RBBP4/RbAp48, and RBBP7/RbAp46. Interacts with MRFAP1 and RB1. May also interact with one or more as yet undefined members of the TLE (transducin-like enhancer of split) family of transcriptional repressors.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also a component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
messages: Nucleus

9915:LOC109568624
gene id: 9915:LOC109568624
uniprot id: A0A6P5CXL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9915:PSMA8
gene id: 9915:PSMA8
uniprot id: A0A6P5E078
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9915:PARK2
gene id: 9915:PARK2
uniprot id: A0A6P5CC61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RBR family. Parkin subfamily.
messages: Forms an E3 ubiquitin ligase complex.
messages: Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
messages: Mitochondrion
messages: cytosol

9915:IRF3
gene id: 9915:IRF3
uniprot id: A0A6P5D7X3
uniprot id: A0A6P5D9I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Nucleus

9915:LOC109559716
gene id: 9915:LOC109559716
uniprot id: A0A6P5BVM6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:KCNE2
gene id: 9915:KCNE2
uniprot id: A0A6P5C9Y9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

9915:TAF15
gene id: 9915:TAF15
uniprot id: A0A6P5DIU8
uniprot id: A0A6P5DJC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

9915:DOCK7
gene id: 9915:DOCK7
uniprot id: A0A6P5B2W6
uniprot id: A0A6P5B2X1
uniprot id: A0A6P5B7P5
uniprot id: A0A6P5BHU5
uniprot id: A0A6P5BP16
uniprot id: A0A6P5BP46
names: Similarity
messages: Belongs to the DOCK family.

9915:LOC109568427
gene id: 9915:LOC109568427
uniprot id: A0A6P5CWS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9915:AGBL3
gene id: 9915:AGBL3
uniprot id: A0A6P5BCG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

9915:RBCK1
gene id: 9915:RBCK1
uniprot id: A0A6P5CR89
uniprot id: A0A6P5CS89
names: Similarity
messages: Belongs to the RBR family.

9915:PTPRU
gene id: 9915:PTPRU
uniprot id: A0A6P5DDV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

9915:SLX4
gene id: 9915:SLX4
uniprot id: A0A6P5DZ02
uniprot id: A0A6P5DZV0
names: Similarity
messages: Belongs to the SLX4 family.

9915:LOC109555755
gene id: 9915:LOC109555755
uniprot id: A0A6P5B0B1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109569336
gene id: 9915:LOC109569336
uniprot id: A0A6P5CX18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EPHA8
gene id: 9915:EPHA8
uniprot id: A0A6P5DT14
names: Subcellular Location Annotation
messages: Membrane

9915:MLST8
gene id: 9915:MLST8
uniprot id: A0A6P5DYC7
uniprot id: A0A6P5E1U9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LST8 family.
messages: Cytoplasm
messages: Part of the mammalian target of rapamycin complex 1 (mTORC1) which contains MTOR, MLST8, RPTOR, AKT1S1/PRAS40 and DEPTOR. mTORC1 binds to and is inhibited by FKBP12-rapamycin. Part of the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. Contrary to mTORC1, mTORC2 does not bind to and is not sensitive to FKBP12-rapamycin. Interacts directly with MTOR and RPTOR. Interacts with RHEB. Interacts with MEAK7. Interacts with SIK3.
messages: Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC1 phosphorylates and activates S6K1, which then promotes protein synthesis by phosphorylating PDCD4 and targeting it for degradation. Within mTORC1, LST8 interacts directly with MTOR and enhances its kinase activity. In nutrient-poor conditions, stabilizes the MTOR-RPTOR interaction and favors RPTOR-mediated inhibition of MTOR activity. mTORC2 is also activated by growth factors, but seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1. mTORC2 also modulates the phosphorylation of PRKCA.

9915:KDELC1
gene id: 9915:KDELC1
uniprot id: A0A6P5CNJ1
names: Similarity
messages: Belongs to the KDELC family.

9915:SLC25A23
gene id: 9915:SLC25A23
uniprot id: A0A6P5C332
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:NOG
gene id: 9915:NOG
uniprot id: A0A6P5DIX7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.
messages: Secreted

9915:MSH6
gene id: 9915:MSH6
uniprot id: A0A6P5CI25
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

9915:TYRP1
gene id: 9915:TYRP1
uniprot id: A0A6P5C7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane

9915:ITGAE
gene id: 9915:ITGAE
uniprot id: A0A6P5DDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:LOC109565229
gene id: 9915:LOC109565229
uniprot id: A0A6P5CI28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9915:POMT1
gene id: 9915:POMT1
uniprot id: A0A6P5CKG1
uniprot id: A0A6P5CNY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9915:TDO2
gene id: 9915:TDO2
uniprot id: A0A6P5D5S1
uniprot id: A0A6P5D6V8
uniprot id: A0A6P5D975
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NRTN
gene id: 9915:NRTN
uniprot id: A0A6P5C444
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9915:ATG16L1
gene id: 9915:ATG16L1
uniprot id: A0A6P5B4R3
uniprot id: A0A6P5BPQ2
uniprot id: A0A6P5BPT4
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

9915:ATP5F1
gene id: 9915:ATP5F1
uniprot id: A0A6P5BNI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

9915:LOC109576799
gene id: 9915:LOC109576799
uniprot id: A0A6P5DVE5
names: Function
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.

9915:SLC5A1
gene id: 9915:SLC5A1
uniprot id: A0A6P5D695
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:LOC109569853
gene id: 9915:LOC109569853
uniprot id: A0A6P5D1C6
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9915:C5H12orf57
gene id: 9915:C5H12orf57
uniprot id: A0A6P5BSF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

9915:BCAT2
gene id: 9915:BCAT2
uniprot id: A0A6P5DCC1
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

9915:SLC25A3
gene id: 9915:SLC25A3
uniprot id: A0A6P5BTY1
uniprot id: A0A6P5BU01
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

9915:ANKRD34B
gene id: 9915:ANKRD34B
uniprot id: A0A6P5C1Z8
names: Similarity
messages: Belongs to the ANKRD34 family.

9915:PIEZO1
gene id: 9915:PIEZO1
uniprot id: A0A6P5D8E4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIEZO (TC 1.A.75) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SEC16B
gene id: 9915:SEC16B
uniprot id: A0A6P5D2C2
uniprot id: A0A6P5D2S6
uniprot id: A0A6P5D629
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus.
messages: SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.

9915:PGM1
gene id: 9915:PGM1
uniprot id: A0A6P5B2U0
uniprot id: A0A6P5BHT6
names: Similarity
messages: Belongs to the phosphohexose mutase family.

9915:PRPF3
gene id: 9915:PRPF3
uniprot id: A0A6P5AZE8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

9915:LIN54
gene id: 9915:LIN54
uniprot id: A0A6P5BZ31
uniprot id: A0A6P5BZ35
uniprot id: A0A6P5BZ45
uniprot id: A0A6P5BZG5
uniprot id: A0A6P5BZX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

9915:KREMEN1
gene id: 9915:KREMEN1
uniprot id: A0A6P5D2Z2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CLK1
gene id: 9915:CLK1
uniprot id: A0A6P5CZJ3
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:KCNH5
gene id: 9915:KCNH5
uniprot id: A0A6P5CCY0
uniprot id: A0A6P5CE31
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569428
gene id: 9915:LOC109569428
uniprot id: A0A6P5CWG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SELENOK
gene id: 9915:SELENOK
uniprot id: A0A6P5DQU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein K family.
messages: Endoplasmic reticulum membrane

9915:SLBP
gene id: 9915:SLBP
uniprot id: A0A6P5BZX3
names: Similarity
messages: Belongs to the SLBP family.

9915:HDDC2
gene id: 9915:HDDC2
uniprot id: A0A6P5CB05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

9915:SFT2D1
gene id: 9915:SFT2D1
uniprot id: A0A6P5CDS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex.
messages: Membrane

9915:FAR1
gene id: 9915:FAR1
uniprot id: A0A6P5CYB8
uniprot id: A0A6P5CZY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

9915:LOC109559616
gene id: 9915:LOC109559616
uniprot id: A0A6P5BUY3
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

9915:LOC109569701
gene id: 9915:LOC109569701
uniprot id: A0A6P5D0L3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:POLR2G
gene id: 9915:POLR2G
uniprot id: A0A6P5BKR9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Component of the RNA polymerase II (Pol II) complex consisting of 12 subunits. RPB4 and RPB7 form a subcomplex that protrudes from the 10-subunit Pol II core complex.
messages: Nucleus

9915:VEGFD
gene id: 9915:VEGFD
uniprot id: A0A6P5BMM6
uniprot id: A0A6P5BMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Secreted

9915:CCNDBP1
gene id: 9915:CCNDBP1
uniprot id: A0A6P5CE68
uniprot id: A0A6P5CGW7
names: Similarity
names: Subunit
messages: Belongs to the CCNDBP1 family.
messages: Interacts with CCND1 and GRAP2. May also interact with COPS5, RPLP0, SIRT6, SYF2 and TCF3.

9915:CLCC1
gene id: 9915:CLCC1
uniprot id: A0A6P5BNN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane
messages: Nucleus membrane

9915:LOC109566384
gene id: 9915:LOC109566384
uniprot id: A0A6P5CL93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109563355
gene id: 9915:LOC109563355
uniprot id: A0A6P5CAZ3
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9915:NGF
gene id: 9915:NGF
uniprot id: A0A6P5B639
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted

9915:MTM1
gene id: 9915:MTM1
uniprot id: A0A6P5AYP8
uniprot id: A0A6P5B4I4
uniprot id: A0A6P5BG22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

9915:GRID1
gene id: 9915:GRID1
uniprot id: A0A6P5BI43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:GPR157
gene id: 9915:GPR157
uniprot id: A0A6P5D3W5
names: Subcellular Location Annotation
messages: Membrane

9915:PFKFB4
gene id: 9915:PFKFB4
uniprot id: A0A6P5DNV8
uniprot id: A0A6P5DNW2
uniprot id: A0A6P5DPG1
uniprot id: A0A6P5DQE6
uniprot id: A0A6P5DSK4
uniprot id: A0A6P5DSX9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9915:DXO
gene id: 9915:DXO
uniprot id: A0A6P5DTB8
uniprot id: A0A6P5DVQ2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Binds 2 magnesium ions.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

9915:NPEPPS
gene id: 9915:NPEPPS
uniprot id: A0A6P5DG14
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9915:SLC2A10
gene id: 9915:SLC2A10
uniprot id: A0A6P5CRA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

9915:SMUG1
gene id: 9915:SMUG1
uniprot id: A0A6P5BCR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. SMUG1 family.
messages: Nucleus

9915:LOC109555738
gene id: 9915:LOC109555738
uniprot id: A0A6P5B5N2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109554066
gene id: 9915:LOC109554066
uniprot id: A0A6P5BJB8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CLASP2
gene id: 9915:CLASP2
uniprot id: A0A6P5DNX3
uniprot id: A0A6P5DNX7
uniprot id: A0A6P5DPH7
uniprot id: A0A6P5DPI0
uniprot id: A0A6P5DSM1
uniprot id: A0A6P5DSM6
uniprot id: A0A6P5DSN1
uniprot id: A0A6P5DSZ6
uniprot id: A0A6P5DT01
names: Subcellular Location Annotation
messages: kinetochore

9915:LOC109561076
gene id: 9915:LOC109561076
uniprot id: A0A6P5C0E0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

9915:ORAI3
gene id: 9915:ORAI3
uniprot id: A0A6P5E0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

9915:NCBP3
gene id: 9915:NCBP3
uniprot id: A0A6P5DFL0
names: Similarity
messages: Belongs to the NCBP3 family.

9915:TRMT10C
gene id: 9915:TRMT10C
uniprot id: A0A6P5CR60
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

9915:CCNB2
gene id: 9915:CCNB2
uniprot id: A0A6P5CHC2
names: Similarity
messages: Belongs to the cyclin family.

9915:LOC109570930
gene id: 9915:LOC109570930
uniprot id: A0A6P5D438
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SUB1
gene id: 9915:SUB1
uniprot id: A0A6P5DK27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transcriptional coactivator PC4 family.
messages: General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA).
messages: Homodimer. Interacts with CSTF2.
messages: Nucleus

9915:MLEC
gene id: 9915:MLEC
uniprot id: A0A6P5D500
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:CMTM8
gene id: 9915:CMTM8
uniprot id: A0A6P5DQN2
names: Subcellular Location Annotation
messages: Membrane

9915:GRM4
gene id: 9915:GRM4
uniprot id: A0A6P5DU14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9915:LOC109572720
gene id: 9915:LOC109572720
uniprot id: A0A6P5DDZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:COPB2
gene id: 9915:COPB2
uniprot id: A0A6P5CA66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

9915:DGKD
gene id: 9915:DGKD
uniprot id: A0A6P5BIX2
uniprot id: A0A6P5BPQ5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:HIGD1A
gene id: 9915:HIGD1A
uniprot id: A0A6P5DU38
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9915:LOC109561029
gene id: 9915:LOC109561029
uniprot id: A0A6P5C1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568207
gene id: 9915:LOC109568207
uniprot id: A0A6P5CTG7
names: Caution
names: Similarity
messages: Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NHSL1
gene id: 9915:NHSL1
uniprot id: A0A6P5CC40
names: Similarity
messages: Belongs to the NHS family.

9915:IPO13
gene id: 9915:IPO13
uniprot id: A0A6P5BID3
uniprot id: A0A6P5BPD9
uniprot id: A0A6P5BPG2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the importin beta family.
messages: Cytoplasm
messages: Interacts with UBC9, RAN, RBM8A, eIF-1A and PAX6.
messages: Nucleus

9915:FAM83H
gene id: 9915:FAM83H
uniprot id: A0A6P5CTU2
uniprot id: A0A6P5CV99
names: Similarity
messages: Belongs to the FAM83 family.

9915:DNAJB12
gene id: 9915:DNAJB12
uniprot id: A0A6P5ARX5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569000
gene id: 9915:LOC109569000
uniprot id: A0A6P5CYJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109578080
gene id: 9915:LOC109578080
uniprot id: A0A6P5E0H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DDIT4L
gene id: 9915:DDIT4L
uniprot id: A0A6P5BY53
names: Similarity
messages: Belongs to the DDIT4 family.

9915:LOC109565763
gene id: 9915:LOC109565763
uniprot id: A0A6P5CIE5
names: Similarity
messages: Belongs to the histone H3 family.

9915:GNG3
gene id: 9915:GNG3
uniprot id: A0A6P5ATY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:GCDH
gene id: 9915:GCDH
uniprot id: A0A6P5C1W3
uniprot id: A0A6P5C2B0
uniprot id: A0A6P5C328
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9915:C11H2orf49
gene id: 9915:C11H2orf49
uniprot id: A0A6P5CJI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

9915:LOC109558160
gene id: 9915:LOC109558160
uniprot id: A0A6P5BLJ6
names: Similarity
messages: Belongs to the histone H2B family.

9915:GNRHR
gene id: 9915:GNRHR
uniprot id: A0A6P5BWP3
uniprot id: A0A6P5BXB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for gonadotropin releasing hormone (GnRH) that mediates the action of GnRH to stimulate the secretion of the gonadotropic hormones luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This receptor mediates its action by association with G-proteins that activate a phosphatidylinositol-calcium second messenger system.

9915:GALK2
gene id: 9915:GALK2
uniprot id: A0A6P5CEU6
uniprot id: A0A6P5CHM6
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

9915:SLC12A9
gene id: 9915:SLC12A9
uniprot id: A0A6P5DYY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

9915:PGLS
gene id: 9915:PGLS
uniprot id: A0A6P5C1F3
uniprot id: A0A6P5C1U1
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

9915:LOC109569021
gene id: 9915:LOC109569021
uniprot id: A0A6P5CYK9
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9915:LOC109564706
gene id: 9915:LOC109564706
uniprot id: A0A6P5CE83
names: Similarity
messages: Belongs to the cystatin family.

9915:EPHA6
gene id: 9915:EPHA6
uniprot id: A0A6P5CC30
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555919
gene id: 9915:LOC109555919
uniprot id: A0A6P5B193
uniprot id: A0A6P5BND4
uniprot id: A0A6P5BNG4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

9915:ICAM2
gene id: 9915:ICAM2
uniprot id: A0A6P5DFU7
uniprot id: A0A6P5DIR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9915:POLR1E
gene id: 9915:POLR1E
uniprot id: A0A6P5C854
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

9915:HPSE2
gene id: 9915:HPSE2
uniprot id: A0A6P5B8A8
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

9915:AP3M1
gene id: 9915:AP3M1
uniprot id: A0A6P5BA23
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

9915:GRAP2
gene id: 9915:GRAP2
uniprot id: A0A6P5BVX4
names: Similarity
messages: Belongs to the GRB2/sem-5/DRK family.

9915:MRPS16
gene id: 9915:MRPS16
uniprot id: A0A6P5BHZ1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

9915:BBS2
gene id: 9915:BBS2
uniprot id: A0A6P5D9X7
names: Subcellular Location Annotation
messages: centriolar satellite
messages: cilium membrane

9915:LOC109558007
gene id: 9915:LOC109558007
uniprot id: A0A6P5BRK9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:AKAP8L
gene id: 9915:AKAP8L
uniprot id: A0A6P5C1N1
uniprot id: A0A6P5C1Q5
uniprot id: A0A6P5C216
uniprot id: A0A6P5C2V4
names: Similarity
messages: Belongs to the AKAP95 family.

9915:SDC1
gene id: 9915:SDC1
uniprot id: A0A6P5CL43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

9915:ZAN
gene id: 9915:ZAN
uniprot id: A0A6P5DXM1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109578833
gene id: 9915:LOC109578833
uniprot id: A0A6P5E3P3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Inflammasome

9915:CXHXorf23
gene id: 9915:CXHXorf23
uniprot id: A0A6P5AXK6
uniprot id: A0A6P5B3H8
uniprot id: A0A6P5BFC9
uniprot id: A0A6P5BLV5
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

9915:TBX18
gene id: 9915:TBX18
uniprot id: A0A6P5CB19
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:LOC109569248
gene id: 9915:LOC109569248
uniprot id: A0A6P5CWS7
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:APEX2
gene id: 9915:APEX2
uniprot id: A0A6P5B4W1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9915:LOC109578251
gene id: 9915:LOC109578251
uniprot id: A0A6P5E0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the myelin P0 protein family.
messages: Cell membrane
messages: Homodimer and homotetramer.
messages: Is an adhesion molecule necessary for normal myelination in the peripheral nervous system. It mediates adhesion between adjacent myelin wraps and ultimately drives myelin compaction.
messages: Membrane

9915:AP3S1
gene id: 9915:AP3S1
uniprot id: A0A6P5CCQ5
uniprot id: A0A6P5CDU3
uniprot id: A0A6P5CEY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

9915:LOC109564507
gene id: 9915:LOC109564507
uniprot id: A0A6P5CCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109567844
gene id: 9915:LOC109567844
uniprot id: A0A6P5CUA3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BZW1
gene id: 9915:BZW1
uniprot id: A0A6P5CWY9
uniprot id: A0A6P5CZI2
names: Similarity
messages: Belongs to the BZW family.

9915:LAMA2
gene id: 9915:LAMA2
uniprot id: A0A6P5CBI8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9915:WFIKKN1
gene id: 9915:WFIKKN1
uniprot id: A0A6P5E039
names: Similarity
messages: Belongs to the WFIKKN family.

9915:PIGF
gene id: 9915:PIGF
uniprot id: A0A6P5CI08
uniprot id: A0A6P5CK97
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:FOXA1
gene id: 9915:FOXA1
uniprot id: A0A6P5DNV5
names: Subcellular Location Annotation
messages: Nucleus

9915:FOXI2
gene id: 9915:FOXI2
uniprot id: A0A6P5E4C4
names: Subcellular Location Annotation
messages: Nucleus

9915:FAM3A
gene id: 9915:FAM3A
uniprot id: A0A6P5B4E3
uniprot id: A0A6P5BG01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9915:GRB2
gene id: 9915:GRB2
uniprot id: A0A6P5DGF5
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

9915:MMP15
gene id: 9915:MMP15
uniprot id: A0A6P5DAF9
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:C7H5orf24
gene id: 9915:C7H5orf24
uniprot id: A0A6P5C4J0
names: Similarity
messages: Belongs to the UPF0461 family.

9915:CERS3
gene id: 9915:CERS3
uniprot id: A0A6P5DLN2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

9915:TNFRSF8
gene id: 9915:TNFRSF8
uniprot id: A0A6P5D2M7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:KRT4
gene id: 9915:KRT4
uniprot id: A0A6P5BN36
names: Similarity
messages: Belongs to the intermediate filament family.

9915:CSNK2A2
gene id: 9915:CSNK2A2
uniprot id: A0A6P5DC07
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:CA13
gene id: 9915:CA13
uniprot id: A0A6P5CW38
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

9915:LOC109574695
gene id: 9915:LOC109574695
uniprot id: A0A6P5DLV0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

9915:LOC109569444
gene id: 9915:LOC109569444
uniprot id: A0A6P5CZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPS7
gene id: 9915:RPS7
uniprot id: A0A6P5CBD5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.
messages: Required for rRNA maturation.

9915:TACR1
gene id: 9915:TACR1
uniprot id: A0A6P5CKH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

9915:GPR15
gene id: 9915:GPR15
uniprot id: A0A6P5CCV4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:SYF2
gene id: 9915:SYF2
uniprot id: A0A6P5DST0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

9915:AGAP1
gene id: 9915:AGAP1
uniprot id: A0A6P5BQ83
names: Similarity
messages: Belongs to the centaurin gamma-like family.

9915:SSU72
gene id: 9915:SSU72
uniprot id: A0A6P5D435
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

9915:FABP7
gene id: 9915:FABP7
uniprot id: A0A6P5CBD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9915:LOC109558447
gene id: 9915:LOC109558447
uniprot id: A0A6P5BE80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568991
gene id: 9915:LOC109568991
uniprot id: A0A6P5CYJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RGS9BP
gene id: 9915:RGS9BP
uniprot id: A0A6P5D8D9
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

9915:NOP2
gene id: 9915:NOP2
uniprot id: A0A6P5BMR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

9915:PBX4
gene id: 9915:PBX4
uniprot id: A0A6P5C157
uniprot id: A0A6P5C1H2
uniprot id: A0A6P5C1H9
uniprot id: A0A6P5C281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9915:AQP5
gene id: 9915:AQP5
uniprot id: A0A6P5BFT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

9915:GPR50
gene id: 9915:GPR50
uniprot id: A0A6P5B2J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:PITX2
gene id: 9915:PITX2
uniprot id: A0A6P5BX29
uniprot id: A0A6P5BX48
uniprot id: A0A6P5BXK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

9915:LOC109554169
gene id: 9915:LOC109554169
uniprot id: A0A6P5AZU3
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:LOC109574998
gene id: 9915:LOC109574998
uniprot id: A0A6P5DLD2
uniprot id: A0A6P5DN23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Nucleus

9915:B3GALT6
gene id: 9915:B3GALT6
uniprot id: A0A6P5D1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:PADI6
gene id: 9915:PADI6
uniprot id: A0A6P5DTK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9915:HAUS1
gene id: 9915:HAUS1
uniprot id: A0A6P5DVY8
uniprot id: A0A6P5E010
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

9915:HS3ST1
gene id: 9915:HS3ST1
uniprot id: A0A6P5C076
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:ATP2C1
gene id: 9915:ATP2C1
uniprot id: A0A6P5BXP0
uniprot id: A0A6P5BYH7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer. Homodimer.
messages: trans-Golgi network membrane

9915:LOC109577074
gene id: 9915:LOC109577074
uniprot id: A0A6P5DSW2
uniprot id: A0A6P5DTZ2
uniprot id: A0A6P5DWG1
uniprot id: A0A6P5DWS8
names: Similarity
messages: Belongs to the MHC class I family.

9915:LOC109574729
gene id: 9915:LOC109574729
uniprot id: A0A6P5DJ83
uniprot id: A0A6P5DLY6
uniprot id: A0A6P5DLZ6
uniprot id: A0A6P5DMG7
uniprot id: A0A6P5DMI9
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109556104
gene id: 9915:LOC109556104
uniprot id: A0A6P5BHJ0
names: Similarity
messages: Belongs to the CLCR family.

9915:TEX10
gene id: 9915:TEX10
uniprot id: A0A6P5C8L7
uniprot id: A0A6P5C9K6
names: Similarity
messages: Belongs to the IPI1/TEX10 family.

9915:KIAA0922
gene id: 9915:KIAA0922
uniprot id: A0A6P5D2S3
names: Similarity
messages: Belongs to the TMEM131 family.

9915:LOC109576860
gene id: 9915:LOC109576860
uniprot id: A0A6P5DVQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9915:CKAP2L
gene id: 9915:CKAP2L
uniprot id: A0A6P5CII2
uniprot id: A0A6P5CJG4
names: Similarity
messages: Belongs to the CKAP2 family.

9915:GPR83
gene id: 9915:GPR83
uniprot id: A0A6P5D1Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:GNAQ
gene id: 9915:GNAQ
uniprot id: A0A6P5C7U3
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

9915:IL17RA
gene id: 9915:IL17RA
uniprot id: A0A6P5BB60
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109569390
gene id: 9915:LOC109569390
uniprot id: A0A6P5CWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109556690
gene id: 9915:LOC109556690
uniprot id: A0A6P5B5F0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HCST
gene id: 9915:HCST
uniprot id: A0A6P5D8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAP10 family.
messages: Membrane

9915:OPN1LW
gene id: 9915:OPN1LW
uniprot id: A0A6P5BMW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

9915:AMH
gene id: 9915:AMH
uniprot id: A0A6P5C3B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Plays an important role in several reproductive functions. Induces Muellerian duct regression during male fetal sexual differentiation and plays a role in Leydig cell differentiation and function. In female acts as a negative regulator of the primordial to primary follicle transition and decreases FSH sensitivity of growing follicles. AMH signals by binding to a specific type-II receptor, AMHR2, that heterodimerizes with type-I receptors (ACVR1 and BMPR1A), and recruiting SMAD proteins that are translocated to the nucleus to regulate target gene expression.
messages: Secreted

9915:DGKK
gene id: 9915:DGKK
uniprot id: A0A6P5B260
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:LOC109556231
gene id: 9915:LOC109556231
uniprot id: A0A6P5BP55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9915:LOC109558599
gene id: 9915:LOC109558599
uniprot id: A0A6P5BS35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PSMC1
gene id: 9915:PSMC1
uniprot id: A0A6P5CG95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

9915:LOC109560108
gene id: 9915:LOC109560108
uniprot id: A0A6P5BN62
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:KLC4
gene id: 9915:KLC4
uniprot id: A0A6P5DRV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

9915:KDELR3
gene id: 9915:KDELR3
uniprot id: A0A6P5BVT6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:GALNT3
gene id: 9915:GALNT3
uniprot id: A0A6P5CPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109554232
gene id: 9915:LOC109554232
uniprot id: A0A6P5AZZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NRG1
gene id: 9915:NRG1
uniprot id: A0A6P5AXK5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Secreted

9915:SLC25A30
gene id: 9915:SLC25A30
uniprot id: A0A6P5CMA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:PRKCQ
gene id: 9915:PRKCQ
uniprot id: A0A6P5CS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

9915:KCNC4
gene id: 9915:KCNC4
uniprot id: A0A6P5B6F5
uniprot id: A0A6P5BH47
uniprot id: A0A6P5BNK3
names: Subcellular Location Annotation
messages: Membrane

9915:RPL5
gene id: 9915:RPL5
uniprot id: A0A6P5BHC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

9915:HSD17B10
gene id: 9915:HSD17B10
uniprot id: A0A6P5BM49
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:DLL4
gene id: 9915:DLL4
uniprot id: A0A6P5CEH2
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

9915:HOXD11
gene id: 9915:HOXD11
uniprot id: A0A6P5CLD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:SLC5A8
gene id: 9915:SLC5A8
uniprot id: A0A6P5BU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:PARP3
gene id: 9915:PARP3
uniprot id: A0A6P5DMT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARTD/PARP family.
messages: Nucleus

9915:SLC4A3
gene id: 9915:SLC4A3
uniprot id: A0A6P5D5M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

9915:ATP5H
gene id: 9915:ATP5H
uniprot id: A0A6P5DJJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

9915:VIPR1
gene id: 9915:VIPR1
uniprot id: A0A6P5DQ44
uniprot id: A0A6P5DQM6
uniprot id: A0A6P5DRM3
uniprot id: A0A6P5DTX8
uniprot id: A0A6P5DU42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9915:VPS54
gene id: 9915:VPS54
uniprot id: A0A6P5CIU4
uniprot id: A0A6P5CKE9
uniprot id: A0A6P5CM18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

9915:RPL36AL
gene id: 9915:RPL36AL
uniprot id: A0A6P5CGX2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9915:VEZT
gene id: 9915:VEZT
uniprot id: A0A6P5BCN4
uniprot id: A0A6P5BMW3
uniprot id: A0A6P5BSK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

9915:ITGA11
gene id: 9915:ITGA11
uniprot id: A0A6P5CDH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:AKR1D1
gene id: 9915:AKR1D1
uniprot id: A0A6P5B8J4
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:LOC109569005
gene id: 9915:LOC109569005
uniprot id: A0A6P5CYK3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BDH1
gene id: 9915:BDH1
uniprot id: A0A6P5BI76
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:STAR
gene id: 9915:STAR
uniprot id: A0A6P5AQN6
uniprot id: A0A6P5BHV1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

9915:DRD3
gene id: 9915:DRD3
uniprot id: A0A6P5CC50
uniprot id: A0A6P5CCP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

9915:LOC109560993
gene id: 9915:LOC109560993
uniprot id: A0A6P5C069
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109572186
gene id: 9915:LOC109572186
uniprot id: A0A6P5DA57
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555734
gene id: 9915:LOC109555734
uniprot id: A0A6P5B5M7
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109571509
gene id: 9915:LOC109571509
uniprot id: A0A6P5D9G1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109579096
gene id: 9915:LOC109579096
uniprot id: A0A6P5E0U3
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:LOC109568894
gene id: 9915:LOC109568894
uniprot id: A0A6P5CYA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554674
gene id: 9915:LOC109554674
uniprot id: A0A6P5B1U5
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

9915:LOC109569398
gene id: 9915:LOC109569398
uniprot id: A0A6P5CX63
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TSHR
gene id: 9915:TSHR
uniprot id: A0A6P5CG67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Interacts with heterodimer GPHA2:GPHB5; this interaction stimulates cAMP production. Interacts (via the PDZ-binding motif) with SCRIB; regulates TSHR trafficking and function.
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

9915:CLTC
gene id: 9915:CLTC
uniprot id: A0A6P5DFK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

9915:AP2S1
gene id: 9915:AP2S1
uniprot id: A0A6P5DBD4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: coated pit

9915:B4GALNT3
gene id: 9915:B4GALNT3
uniprot id: A0A6P5BB55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

9915:DPT
gene id: 9915:DPT
uniprot id: A0A6P5D1S4
names: Similarity
messages: Belongs to the dermatopontin family.

9915:ATP8B1
gene id: 9915:ATP8B1
uniprot id: A0A6P5DZX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9915:LOC109554227
gene id: 9915:LOC109554227
uniprot id: A0A6P5BBX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ZHX2
gene id: 9915:ZHX2
uniprot id: A0A6P5CWX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

9915:KANSL2
gene id: 9915:KANSL2
uniprot id: A0A6P5BDM3
uniprot id: A0A6P5BFY1
uniprot id: A0A6P5BNE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription.
messages: Component of the NSL complex at least composed of MOF/KAT8, KANSL1, KANSL2, KANSL3, MCRS1, PHF20, OGT1/OGT, WDR5 and HCFC1.
messages: Nucleus

9915:PFN1
gene id: 9915:PFN1
uniprot id: A0A6P5DHW6
names: Similarity
messages: Belongs to the profilin family.

9915:LOC109555654
gene id: 9915:LOC109555654
uniprot id: A0A6P5BGL5
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:DDR2
gene id: 9915:DDR2
uniprot id: A0A6P5DVU9
uniprot id: A0A6P5DVW2
uniprot id: A0A6P5DVX2
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109560925
gene id: 9915:LOC109560925
uniprot id: A0A6P5C029
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576636
gene id: 9915:LOC109576636
uniprot id: A0A6P5DV24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:NUDT5
gene id: 9915:NUDT5
uniprot id: A0A6P5CQX3
uniprot id: A0A6P5CS06
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9915:USO1
gene id: 9915:USO1
uniprot id: A0A6P5BYV4
uniprot id: A0A6P5BZ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VDP/USO1/EDE1 family.
messages: Membrane

9915:LOC109576892
gene id: 9915:LOC109576892
uniprot id: A0A6P5DT76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:COQ10A
gene id: 9915:COQ10A
uniprot id: A0A6P5BTN8
uniprot id: A0A6P5BTP5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9915:LOC109569139
gene id: 9915:LOC109569139
uniprot id: A0A6P5CXY0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DNAJC10
gene id: 9915:DNAJC10
uniprot id: A0A6P5CI18
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins.
messages: Endoplasmic reticulum lumen

9915:DNAH3
gene id: 9915:DNAH3
uniprot id: A0A6P5DWF3
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:POU3F2
gene id: 9915:POU3F2
uniprot id: A0A6P5CBI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

9915:LOC109565605
gene id: 9915:LOC109565605
uniprot id: A0A6P5CJJ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TPD52L3
gene id: 9915:TPD52L3
uniprot id: A0A6P5C713
names: Similarity
messages: Belongs to the TPD52 family.

9915:GPR180
gene id: 9915:GPR180
uniprot id: A0A6P5CQN1
names: Subcellular Location Annotation
messages: Membrane

9915:PDE3B
gene id: 9915:PDE3B
uniprot id: A0A6P5CXI4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:SNPH
gene id: 9915:SNPH
uniprot id: A0A6P5CPW1
uniprot id: A0A6P5CQD6
uniprot id: A0A6P5CR69
names: Subcellular Location Annotation
messages: Membrane

9915:RFC4
gene id: 9915:RFC4
uniprot id: A0A6P5BQB0
names: Similarity
messages: Belongs to the activator 1 small subunits family.

9915:LOC109578078
gene id: 9915:LOC109578078
uniprot id: A0A6P5DZZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPL27
gene id: 9915:RPL27
uniprot id: A0A6P5DJS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

9915:ANKRD13A
gene id: 9915:ANKRD13A
uniprot id: A0A6P5D5A2
names: Function
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Membrane
messages: Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.

9915:GARS
gene id: 9915:GARS
uniprot id: A0A6P5BK77
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Homodimer.

9915:KCNQ4
gene id: 9915:KCNQ4
uniprot id: A0A6P5BPH5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109564500
gene id: 9915:LOC109564500
uniprot id: A0A6P5CCT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BLOC1S5
gene id: 9915:BLOC1S5
uniprot id: A0A6P5B249
names: Similarity
messages: Belongs to the BLOC1S5 family.

9915:INSM2
gene id: 9915:INSM2
uniprot id: A0A6P5DP13
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109568988
gene id: 9915:LOC109568988
uniprot id: A0A6P5CXM2
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOX
gene id: 9915:LOX
uniprot id: A0A6P5C3P2
uniprot id: A0A6P5C3U7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

9915:LOC109556816
gene id: 9915:LOC109556816
uniprot id: A0A6P5BA63
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:SLC1A3
gene id: 9915:SLC1A3
uniprot id: A0A6P5DK68
uniprot id: A0A6P5DMT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9915:LOC109558715
gene id: 9915:LOC109558715
uniprot id: A0A6P5BM96
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

9915:NAAA
gene id: 9915:NAAA
uniprot id: A0A6P5BYV8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acid ceramidase family.
messages: Heterodimer.
messages: Lysosome

9915:IL36RN
gene id: 9915:IL36RN
uniprot id: A0A6P5CID3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9915:LOC109563481
gene id: 9915:LOC109563481
uniprot id: A0A6P5CWI9
names: Similarity
messages: Belongs to the APC15 family.

9915:MTMR8
gene id: 9915:MTMR8
uniprot id: A0A6P5B572
uniprot id: A0A6P5BMT1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

9915:LOC109576662
gene id: 9915:LOC109576662
uniprot id: A0A6P5DUX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:CAST
gene id: 9915:CAST
uniprot id: A0A6P5C5U7
uniprot id: A0A6P5C5V2
uniprot id: A0A6P5C5W9
uniprot id: A0A6P5C607
uniprot id: A0A6P5C6C3
uniprot id: A0A6P5C6C9
uniprot id: A0A6P5C6D1
uniprot id: A0A6P5C780
uniprot id: A0A6P5C791
names: Function
names: Similarity
messages: Belongs to the protease inhibitor I27 (calpastatin) family.
messages: Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue.

9915:LOC109577203
gene id: 9915:LOC109577203
uniprot id: A0A6P5DUI5
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

9915:B4GALNT1
gene id: 9915:B4GALNT1
uniprot id: A0A6P5BTE8
uniprot id: A0A6P5BTF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109569389
gene id: 9915:LOC109569389
uniprot id: A0A6P5CYS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LONP1
gene id: 9915:LONP1
uniprot id: A0A6P5C2U0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer. Organized in a ring with a central cavity. The ATP-binding and proteolytic domains (AP-domain) form a hexameric chamber, while the N-terminal domain is arranged as a trimer of dimers. DNA and RNA binding is stimulated by substrate and inhibited by ATP binding. Interacts with TWNK and mitochondrial DNA polymerase subunit POLG.
messages: Mitochondrion matrix

9915:EVA1B
gene id: 9915:EVA1B
uniprot id: A0A6P5B945
names: Similarity
messages: Belongs to the EVA1 family.

9915:LOC109572201
gene id: 9915:LOC109572201
uniprot id: A0A6P5D7U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:ADGRE5
gene id: 9915:ADGRE5
uniprot id: A0A6P5C1P3
uniprot id: A0A6P5C245
uniprot id: A0A6P5C2W6
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109575867
gene id: 9915:LOC109575867
uniprot id: A0A6P5DRA2
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

9915:ANXA9
gene id: 9915:ANXA9
uniprot id: A0A6P5B3M3
uniprot id: A0A6P5B3P1
uniprot id: A0A6P5BM04
uniprot id: A0A6P5BM21
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

9915:GRHL1
gene id: 9915:GRHL1
uniprot id: A0A6P5CJL3
uniprot id: A0A6P5CKT8
names: Subcellular Location Annotation
messages: Nucleus

9915:SGCD
gene id: 9915:SGCD
uniprot id: A0A6P5C5F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

9915:LOC109561438
gene id: 9915:LOC109561438
uniprot id: A0A6P5C1I3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Cytoplasm
messages: Monomer.

9915:LOC109559505
gene id: 9915:LOC109559505
uniprot id: A0A6P5BUE0
uniprot id: A0A6P5BUF1
uniprot id: A0A6P5BUF3
names: Similarity
messages: Belongs to the apolipoprotein L family.

9915:LOC109557464
gene id: 9915:LOC109557464
uniprot id: A0A6P5BBQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:MMAA
gene id: 9915:MMAA
uniprot id: A0A6P5D5T3
uniprot id: A0A6P5D6Y2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

9915:SLC26A9
gene id: 9915:SLC26A9
uniprot id: A0A6P5D2L9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: DIDS- and thiosulfate- sensitive anion exchanger mediating chloride, sulfate and oxalate transport.
messages: Membrane

9915:MRPS26
gene id: 9915:MRPS26
uniprot id: A0A6P5CN54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

9915:ADAMTS14
gene id: 9915:ADAMTS14
uniprot id: A0A6P5ASM3
uniprot id: A0A6P5BAZ5
uniprot id: A0A6P5BIZ8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:TBX20
gene id: 9915:TBX20
uniprot id: A0A6P5B7A9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:ITGA4
gene id: 9915:ITGA4
uniprot id: A0A6P5CHG7
uniprot id: A0A6P5CIW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:GATA6
gene id: 9915:GATA6
uniprot id: A0A6P5DUF3
names: Subcellular Location Annotation
messages: Nucleus

9915:CCT6A
gene id: 9915:CCT6A
uniprot id: A0A6P5DXW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

9915:PTGES3
gene id: 9915:PTGES3
uniprot id: A0A6P5BTK7
uniprot id: A0A6P5BTM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p23/wos2 family.
messages: Cytoplasm
messages: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation.
messages: Forms a complex with HSP70, HSP90 and other chaperones.

9915:FAM3B
gene id: 9915:FAM3B
uniprot id: A0A6P5BYU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

9915:LOC109565553
gene id: 9915:LOC109565553
uniprot id: A0A6P5CI70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

9915:SAG
gene id: 9915:SAG
uniprot id: A0A6P5B9D4
names: Similarity
messages: Belongs to the arrestin family.

9915:MC5R
gene id: 9915:MC5R
uniprot id: A0A6P5DVZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.

9915:ACHE
gene id: 9915:ACHE
uniprot id: A0A6P5DZM0
uniprot id: A0A6P5DZT9
uniprot id: A0A6P5E0H0
uniprot id: A0A6P5E2Z4
uniprot id: A0A6P5E3E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9915:ATP5E
gene id: 9915:ATP5E
uniprot id: A0A6P5CS18
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9915:LOC109558741
gene id: 9915:LOC109558741
uniprot id: A0A6P5BEM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DNAJB14
gene id: 9915:DNAJB14
uniprot id: A0A6P5BXD3
uniprot id: A0A6P5BXU1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109578737
gene id: 9915:LOC109578737
uniprot id: A0A6P5DZJ1
uniprot id: A0A6P5E0E2
uniprot id: A0A6P5E0E7
uniprot id: A0A6P5E2W8
uniprot id: A0A6P5E3C4
names: Subcellular Location Annotation
messages: Nucleus

9915:ACVR2A
gene id: 9915:ACVR2A
uniprot id: A0A6P5CTV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9915:CDC14B
gene id: 9915:CDC14B
uniprot id: A0A6P5C8V3
uniprot id: A0A6P5C974
uniprot id: A0A6P5C9D3
uniprot id: A0A6P5C9D8
uniprot id: A0A6P5C9E4
uniprot id: A0A6P5C9G5
uniprot id: A0A6P5C9G8
uniprot id: A0A6P5C9H2
uniprot id: A0A6P5CAD7
uniprot id: A0A6P5CAE2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

9915:CCNA1
gene id: 9915:CCNA1
uniprot id: A0A6P5CLE6
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

9915:CDCA5
gene id: 9915:CDCA5
uniprot id: A0A6P5BKH4
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

9915:RBFOX3
gene id: 9915:RBFOX3
uniprot id: A0A6P5DIY8
uniprot id: A0A6P5DK14
uniprot id: A0A6P5DLY7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

9915:LOC109565521
gene id: 9915:LOC109565521
uniprot id: A0A6P5CI54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MTCH2
gene id: 9915:MTCH2
uniprot id: A0A6P5CYY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:DIEXF
gene id: 9915:DIEXF
uniprot id: A0A6P5D1R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

9915:LOC109565286
gene id: 9915:LOC109565286
uniprot id: A0A6P5CH62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

9915:TASP1
gene id: 9915:TASP1
uniprot id: A0A6P5CRY6
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

9915:DBNDD2
gene id: 9915:DBNDD2
uniprot id: A0A6P5CPM3
names: Similarity
messages: Belongs to the dysbindin family.

9915:TAS2R38
gene id: 9915:TAS2R38
uniprot id: A0A6P5BLJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:FRZB
gene id: 9915:FRZB
uniprot id: A0A6P5CH68
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

9915:GLUL
gene id: 9915:GLUL
uniprot id: A0A6P5D1Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamine synthetase family.
messages: Cell membrane
messages: Membrane
messages: Microsome

9915:DGKA
gene id: 9915:DGKA
uniprot id: A0A6P5BTS6
uniprot id: A0A6P5BTS8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:WBP4
gene id: 9915:WBP4
uniprot id: A0A6P5CNM1
names: Subcellular Location Annotation
messages: Nucleus

9915:SNRPC
gene id: 9915:SNRPC
uniprot id: A0A6P5DVV5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the U1 small nuclear ribonucleoprotein C family.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. snrpc/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
messages: Nucleus
messages: U1 snRNP is composed of the 7 core Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP, and at least 3 U1 snRNP-specific proteins SNRNP70/U1-70K, SNRPA/U1-A and SNRPC/U1-C. SNRPC/U1-C interacts with U1 snRNA and the 5' splice-site region of the pre-mRNA.

9915:ZDHHC6
gene id: 9915:ZDHHC6
uniprot id: A0A6P5AW72
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:C7H5orf30
gene id: 9915:C7H5orf30
uniprot id: A0A6P5C628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UNC119-binding protein family.
messages: Cytoplasm
messages: cilium

9915:FLT3
gene id: 9915:FLT3
uniprot id: A0A6P5CMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

9915:FAM25A
gene id: 9915:FAM25A
uniprot id: A0A6P5BIK7
names: Similarity
messages: Belongs to the FAM25 family.

9915:LOC109569163
gene id: 9915:LOC109569163
uniprot id: A0A6P5CWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MED11
gene id: 9915:MED11
uniprot id: A0A6P5DF44
uniprot id: A0A6P5DI28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 11 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:LOC109569157
gene id: 9915:LOC109569157
uniprot id: A0A6P5CWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MCM6
gene id: 9915:MCM6
uniprot id: A0A6P5CSH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

9915:ULK3
gene id: 9915:ULK3
uniprot id: A0A6P5DLZ4
uniprot id: A0A6P5DQH1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:EFNA1
gene id: 9915:EFNA1
uniprot id: A0A6P5BIG4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:GJA3
gene id: 9915:GJA3
uniprot id: A0A6P5CP33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:ONECUT1
gene id: 9915:ONECUT1
uniprot id: A0A6P5CG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

9915:LOC109571714
gene id: 9915:LOC109571714
uniprot id: A0A6P5D7T5
names: Subcellular Location Annotation
messages: Sarcoplasmic reticulum membrane

9915:CD3D
gene id: 9915:CD3D
uniprot id: A0A6P5D1T3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:HSPH1
gene id: 9915:HSPH1
uniprot id: A0A6P5CLJ6
uniprot id: A0A6P5CNE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

9915:LSM6
gene id: 9915:LSM6
uniprot id: A0A6P5D9A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

9915:SPNS3
gene id: 9915:SPNS3
uniprot id: A0A6P5DK31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Spinster (TC 2.A.1.49) family.
messages: Membrane

9915:ATF7IP
gene id: 9915:ATF7IP
uniprot id: A0A6P5BV07
uniprot id: A0A6P5BV10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

9915:HACD3
gene id: 9915:HACD3
uniprot id: A0A6P5CDC2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:TMTC2
gene id: 9915:TMTC2
uniprot id: A0A6P5BF51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9915:MRPL22
gene id: 9915:MRPL22
uniprot id: A0A6P5C5H1
uniprot id: A0A6P5C5J6
uniprot id: A0A6P5C5X8
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

9915:NKX2-5
gene id: 9915:NKX2-5
uniprot id: A0A6P5DMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

9915:SRSF5
gene id: 9915:SRSF5
uniprot id: A0A6P5CGU5
uniprot id: A0A6P5CH69
names: Similarity
messages: Belongs to the splicing factor SR family.

9915:CELF4
gene id: 9915:CELF4
uniprot id: A0A6P5DZR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

9915:RPLP0
gene id: 9915:RPLP0
uniprot id: A0A6P5D3C6
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

9915:NAP1L5
gene id: 9915:NAP1L5
uniprot id: A0A6P5BXI9
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:NR5A2
gene id: 9915:NR5A2
uniprot id: A0A6P5D260
uniprot id: A0A6P5D2M4
uniprot id: A0A6P5D398
uniprot id: A0A6P5D5W9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9915:LOC109568877
gene id: 9915:LOC109568877
uniprot id: A0A6P5CXB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SMAD9
gene id: 9915:SMAD9
uniprot id: A0A6P5CNY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9915:EEF2
gene id: 9915:EEF2
uniprot id: A0A6P5C4C3
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

9915:LOC109558014
gene id: 9915:LOC109558014
uniprot id: A0A6P5BDE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KCNMA1
gene id: 9915:KCNMA1
uniprot id: A0A6P5BI38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

9915:PPP1R12A
gene id: 9915:PPP1R12A
uniprot id: A0A6P5BCG6
uniprot id: A0A6P5BF44
uniprot id: A0A6P5BMR9
uniprot id: A0A6P5BSF3
uniprot id: A0A6P5BSI1
names: Subcellular Location Annotation
names: Subunit
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.
messages: stress fiber

9915:PPP3CC
gene id: 9915:PPP3CC
uniprot id: A0A6P5C876
uniprot id: A0A6P5C8P3
uniprot id: A0A6P5C8P7
uniprot id: A0A6P5C9P3
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

9915:SCUBE3
gene id: 9915:SCUBE3
uniprot id: A0A6P5DV52
uniprot id: A0A6P5DXM3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:DNAAF3
gene id: 9915:DNAAF3
uniprot id: A0A6P5DB47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNAAF3 family.
messages: Cytoplasm
messages: Dynein axonemal particle
messages: Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia.

9915:GDF6
gene id: 9915:GDF6
uniprot id: A0A6P5CUH8
names: Similarity
messages: Belongs to the TGF-beta family.

9915:LOC109559913
gene id: 9915:LOC109559913
uniprot id: A0A6P5BW96
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109577655
gene id: 9915:LOC109577655
uniprot id: A0A6P5DUN2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9915:YOD1
gene id: 9915:YOD1
uniprot id: A0A6P5D2H9
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

9915:LOC109575963
gene id: 9915:LOC109575963
uniprot id: A0A6P5DN39
names: Similarity
messages: Belongs to the alkaline phosphatase family.

9915:ALOX12B
gene id: 9915:ALOX12B
uniprot id: A0A6P5DF16
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:OAS2
gene id: 9915:OAS2
uniprot id: A0A6P5D527
uniprot id: A0A6P5D6X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

9915:MPC1
gene id: 9915:MPC1
uniprot id: A0A6P5CCQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

9915:EFNA4
gene id: 9915:EFNA4
uniprot id: A0A6P5ARV9
uniprot id: A0A6P5ARW7
uniprot id: A0A6P5BAF5
uniprot id: A0A6P5BIJ9
uniprot id: A0A6P5BIK6
uniprot id: A0A6P5BIM1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:UTP3
gene id: 9915:UTP3
uniprot id: A0A6P5BYP7
names: Similarity
messages: Belongs to the SAS10 family.

9915:NXF1
gene id: 9915:NXF1
uniprot id: A0A6P5BJY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm
messages: nucleoplasm

9915:NT5E
gene id: 9915:NT5E
uniprot id: A0A6P5CBG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

9915:RAB27A
gene id: 9915:RAB27A
uniprot id: A0A6P5CEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

9915:LOC109556736
gene id: 9915:LOC109556736
uniprot id: A0A6P5BPZ6
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

9915:ADAMTS7
gene id: 9915:ADAMTS7
uniprot id: A0A6P5DKI4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:DIO2
gene id: 9915:DIO2
uniprot id: A0A6P5CG63
uniprot id: A0A6P5CJ13
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9915:KAT2B
gene id: 9915:KAT2B
uniprot id: A0A6P5CA93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

9915:EIF2S2
gene id: 9915:EIF2S2
uniprot id: A0A6P5CQ72
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

9915:ZFPM1
gene id: 9915:ZFPM1
uniprot id: A0A6P5D618
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109572055
gene id: 9915:LOC109572055
uniprot id: A0A6P5D7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:WASF1
gene id: 9915:WASF1
uniprot id: A0A6P5CAZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

9915:PLA2G1B
gene id: 9915:PLA2G1B
uniprot id: A0A6P5D3J5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9915:LOC109575890
gene id: 9915:LOC109575890
uniprot id: A0A6P5DRP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:GLRB
gene id: 9915:GLRB
uniprot id: A0A6P5D3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:NUSAP1
gene id: 9915:NUSAP1
uniprot id: A0A6P5CE11
uniprot id: A0A6P5CEH7
uniprot id: A0A6P5CGP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUSAP family.
messages: Cytoplasm

9915:SOAT1
gene id: 9915:SOAT1
uniprot id: A0A6P5D4B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:UGDH
gene id: 9915:UGDH
uniprot id: A0A6P5BXW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

9915:IPO5
gene id: 9915:IPO5
uniprot id: A0A6P5CNE8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:PYGB
gene id: 9915:PYGB
uniprot id: A0A6P5CRP5
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the GDA1/CD39 NTPase family.
messages: Belongs to the glycogen phosphorylase family.

9915:SLC5A5
gene id: 9915:SLC5A5
uniprot id: A0A6P5BZX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:LOC109571839
gene id: 9915:LOC109571839
uniprot id: A0A6P5D6U2
names: Subcellular Location Annotation
messages: Membrane

9915:FAM118A
gene id: 9915:FAM118A
uniprot id: A0A6P5BW73
uniprot id: A0A6P5BWE6
names: Similarity
messages: Belongs to the FAM118 family.

9915:CEP290
gene id: 9915:CEP290
uniprot id: A0A6P5BSG1
uniprot id: A0A6P5BSI8
names: Subcellular Location Annotation
messages: cilium basal body

9915:FRG1
gene id: 9915:FRG1
uniprot id: A0A6P5BH15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

9915:LOC109559121
gene id: 9915:LOC109559121
uniprot id: A0A6P5BN87
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

9915:HYOU1
gene id: 9915:HYOU1
uniprot id: A0A6P5CYC3
uniprot id: A0A6P5D000
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9915:ERC2
gene id: 9915:ERC2
uniprot id: A0A6P5DU98
names: Subcellular Location Annotation
messages: Cytoplasm

9915:PRDX2
gene id: 9915:PRDX2
uniprot id: A0A6P5C298
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9915:HSPD1
gene id: 9915:HSPD1
uniprot id: A0A6P5CV65
uniprot id: A0A6P5CXS7
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

9915:LOC109558019
gene id: 9915:LOC109558019
uniprot id: A0A6P5BRL3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TROVE2
gene id: 9915:TROVE2
uniprot id: A0A6P5D1T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ro 60 kDa family.
messages: Cytoplasm

9915:PATL1
gene id: 9915:PATL1
uniprot id: A0A6P5CYK7
uniprot id: A0A6P5D0C6
names: Similarity
messages: Belongs to the PAT1 family.

9915:LCN1
gene id: 9915:LCN1
uniprot id: A0A6P5CPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9915:GJA9
gene id: 9915:GJA9
uniprot id: A0A6P5BPJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:FTMT
gene id: 9915:FTMT
uniprot id: A0A6P5C123
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9915:C8H9orf64
gene id: 9915:C8H9orf64
uniprot id: A0A6P5C968
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

9915:ZKSCAN4
gene id: 9915:ZKSCAN4
uniprot id: A0A6P5DRF6
names: Subcellular Location Annotation
messages: Nucleus

9915:ASIC3
gene id: 9915:ASIC3
uniprot id: A0A6P5BRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

9915:LOC109556703
gene id: 9915:LOC109556703
uniprot id: A0A6P5BPY9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576702
gene id: 9915:LOC109576702
uniprot id: A0A6P5DSP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FITM2
gene id: 9915:FITM2
uniprot id: A0A6P5CPJ9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:PLAT
gene id: 9915:PLAT
uniprot id: A0A6P5AXB5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:NINJ2
gene id: 9915:NINJ2
uniprot id: A0A6P5BVJ9
uniprot id: A0A6P5BVT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

9915:GPHN
gene id: 9915:GPHN
uniprot id: A0A6P5CH21
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released.
messages: In the C-terminal section; belongs to the MoeA family.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

9915:ALCAM
gene id: 9915:ALCAM
uniprot id: A0A6P5CUL1
uniprot id: A0A6P5CUS2
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

9915:APOBEC1
gene id: 9915:APOBEC1
uniprot id: A0A6P5BS33
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

9915:MFSD1
gene id: 9915:MFSD1
uniprot id: A0A6P5BC05
names: Subcellular Location Annotation
messages: Membrane

9915:HRH3
gene id: 9915:HRH3
uniprot id: A0A6P5CTT4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:CAMK2N1
gene id: 9915:CAMK2N1
uniprot id: A0A6P5DI36
names: Similarity
messages: Belongs to the CAMK2N family.

9915:WDR45
gene id: 9915:WDR45
uniprot id: A0A6P5B443
uniprot id: A0A6P5BM67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure

9915:LOC109573244
gene id: 9915:LOC109573244
uniprot id: A0A6P5DEC7
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:LOC109571967
gene id: 9915:LOC109571967
uniprot id: A0A6P5D9E0
uniprot id: A0A6P5DEU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: Dynein axonemal particle
messages: Nucleus
messages: Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding.

9915:CHRNB1
gene id: 9915:CHRNB1
uniprot id: A0A6P5DF54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:ATAT1
gene id: 9915:ATAT1
uniprot id: A0A6P5DU40
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Autoacetylation strongly increases tubulin acetylation.
messages: Belongs to the acetyltransferase ATAT1 family.
messages: Component of the BBSome complex. Interacts with AP2 alpha-adaptins, including AP2A2, but not with AP1 gamma-adaptin (AP1G1/AP1G2); this interaction is required for efficient alpha-tubulin acetylation, hence clathrin-coated pits are sites of microtubule acetylation.
messages: Cytoplasm
messages: Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.
messages: axon
messages: clathrin-coated pit
messages: cytoskeleton
messages: focal adhesion
messages: spindle

9915:LOC109556735
gene id: 9915:LOC109556735
uniprot id: A0A6P5BQ23
names: Similarity
messages: Belongs to the S-100 family.

9915:MMP19
gene id: 9915:MMP19
uniprot id: A0A6P5BTS9
uniprot id: A0A6P5BTT9
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:LGALS3
gene id: 9915:LGALS3
uniprot id: A0A6P5CHX2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9915:NDUFB5
gene id: 9915:NDUFB5
uniprot id: A0A6P5BRC1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:TMSB10
gene id: 9915:TMSB10
uniprot id: A0A6P5CJT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.
messages: cytoskeleton

9915:MTFR2
gene id: 9915:MTFR2
uniprot id: A0A6P5CCH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

9915:LOC109564319
gene id: 9915:LOC109564319
uniprot id: A0A6P5CE51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ABCG1
gene id: 9915:ABCG1
uniprot id: A0A6P5BYZ9
uniprot id: A0A6P5BZ13
uniprot id: A0A6P5BZ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

9915:BDNF
gene id: 9915:BDNF
uniprot id: A0A6P5CVM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NGF-beta family.
messages: During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.
messages: Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
messages: Monomers and homodimers (By similarity). Binds to NTRK2/TRKB. Can form heterodimers with other neurotrophin family members, such as NTF3 and NTF4 (in vitro), but the physiological relevance of this is not clear (By similarity). BDNF precursor form: interacts with the heterodimer formed by NGFR and SORCS2. Mature BDNF has much lower affinity for the heterodimer formed by NGFR and SORCS2.
messages: Monomers and homodimers. Binds to NTRK2/TRKB.
messages: Secreted

9915:NR2F2
gene id: 9915:NR2F2
uniprot id: A0A6P5DMY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:LOC109569362
gene id: 9915:LOC109569362
uniprot id: A0A6P5CX53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109571970
gene id: 9915:LOC109571970
uniprot id: A0A6P5D8K3
names: Similarity
messages: Belongs to the NGF-beta family.

9915:RPS2
gene id: 9915:RPS2
uniprot id: A0A6P5DZA8
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

9915:SUSD3
gene id: 9915:SUSD3
uniprot id: A0A6P5C9J8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:RNF2
gene id: 9915:RNF2
uniprot id: A0A6P5D5N2
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

9915:UGGT2
gene id: 9915:UGGT2
uniprot id: A0A6P5CPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

9915:LOC109573213
gene id: 9915:LOC109573213
uniprot id: A0A6P5DEA5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109563768
gene id: 9915:LOC109563768
uniprot id: A0A6P5CC57
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KRTAP type 6 family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:LOC109558739
gene id: 9915:LOC109558739
uniprot id: A0A6P5BS64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NDE1
gene id: 9915:NDE1
uniprot id: A0A6P5DX26
uniprot id: A0A6P5DX74
uniprot id: A0A6P5DY24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: kinetochore
messages: spindle

9915:GTF2H5
gene id: 9915:GTF2H5
uniprot id: A0A6P5CCM4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

9915:DCP1A
gene id: 9915:DCP1A
uniprot id: A0A6P5DT91
names: Similarity
messages: Belongs to the DCP1 family.

9915:SLC7A11
gene id: 9915:SLC7A11
uniprot id: A0A6P5D380
names: Subcellular Location Annotation
messages: Membrane

9915:FAM13B
gene id: 9915:FAM13B
uniprot id: A0A6P5C0N5
names: Similarity
messages: Belongs to the FAM13 family.

9915:PTGES2
gene id: 9915:PTGES2
uniprot id: A0A6P5CLV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GST superfamily.
messages: Membrane

9915:LOC109557911
gene id: 9915:LOC109557911
uniprot id: A0A6P5BRJ0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555630
gene id: 9915:LOC109555630
uniprot id: A0A6P5BMZ6
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:HHEX
gene id: 9915:HHEX
uniprot id: A0A6P5AWC9
names: Subcellular Location Annotation
messages: Nucleus

9915:PPCS
gene id: 9915:PPCS
uniprot id: A0A6P5BPG5
names: Similarity
messages: Belongs to the PPC synthetase family.

9915:RBFOX1
gene id: 9915:RBFOX1
uniprot id: A0A6P5DXI1
uniprot id: A0A6P5DXI7
uniprot id: A0A6P5DXP4
uniprot id: A0A6P5DYG9
uniprot id: A0A6P5E152
uniprot id: A0A6P5E156
uniprot id: A0A6P5E1M6
uniprot id: A0A6P5E1N0
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: RNA-binding protein that regulates alternative splicing events.

9915:SUGP1
gene id: 9915:SUGP1
uniprot id: A0A6P5C292
names: Subcellular Location Annotation
messages: Nucleus

9915:PLRG1
gene id: 9915:PLRG1
uniprot id: A0A6P5D5H5
uniprot id: A0A6P5D7H8
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

9915:LOC109567574
gene id: 9915:LOC109567574
uniprot id: A0A6P5CQ18
names: Similarity
messages: Belongs to the histone H2B family.

9915:ACVRL1
gene id: 9915:ACVRL1
uniprot id: A0A6P5BSS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9915:PFDN4
gene id: 9915:PFDN4
uniprot id: A0A6P5CU03
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

9915:YWHAB
gene id: 9915:YWHAB
uniprot id: A0A6P5CR55
names: Similarity
messages: Belongs to the 14-3-3 family.

9915:ADAM22
gene id: 9915:ADAM22
uniprot id: A0A6P5B7N0
uniprot id: A0A6P5BKA9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SMPD2
gene id: 9915:SMPD2
uniprot id: A0A6P5CAL7
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

9915:SMC1A
gene id: 9915:SMC1A
uniprot id: A0A6P5BF28
uniprot id: A0A6P5BLQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

9915:RPS27
gene id: 9915:RPS27
uniprot id: A0A6P5AUD0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9915:POMT2
gene id: 9915:POMT2
uniprot id: A0A6P5CHB0
uniprot id: A0A6P5CIW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

9915:AZIN1
gene id: 9915:AZIN1
uniprot id: A0A6P5CTC1
uniprot id: A0A6P5CUN3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9915:GRIN3B
gene id: 9915:GRIN3B
uniprot id: A0A6P5C0M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:HLCS
gene id: 9915:HLCS
uniprot id: A0A6P5C237
uniprot id: A0A6P5C358
names: Similarity
messages: Belongs to the biotin--protein ligase family.

9915:LOC109562260
gene id: 9915:LOC109562260
uniprot id: A0A6P5C5L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109563545
gene id: 9915:LOC109563545
uniprot id: A0A6P5CBJ8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:NSUN5
gene id: 9915:NSUN5
uniprot id: A0A6P5DYQ1
uniprot id: A0A6P5E2M0
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9915:CHD5
gene id: 9915:CHD5
uniprot id: A0A6P5D0E4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

9915:KCNN4
gene id: 9915:KCNN4
uniprot id: A0A6P5DED6
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109553336
gene id: 9915:LOC109553336
uniprot id: A0A6P5BHI7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:SPTY2D1
gene id: 9915:SPTY2D1
uniprot id: A0A6P5B0R9
names: Similarity
messages: Belongs to the SPT2 family.

9915:NUP62
gene id: 9915:NUP62
uniprot id: A0A6P5DB65
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

9915:PLAU
gene id: 9915:PLAU
uniprot id: A0A6P5BIX3
names: Caution
names: Function
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically cleaves the zymogen plasminogen to form the active enzyme plasmin.

9915:GSX1
gene id: 9915:GSX1
uniprot id: A0A6P5CP22
names: Subcellular Location Annotation
messages: Nucleus

9915:NDUFA7
gene id: 9915:NDUFA7
uniprot id: A0A6P5C2X7
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA7 subunit family.
messages: Complex I is composed of 45 different subunits.

9915:LOC109558755
gene id: 9915:LOC109558755
uniprot id: A0A6P5BS88
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TRIM54
gene id: 9915:TRIM54
uniprot id: A0A6P5CJ68
names: Function
names: Subcellular Location Annotation
messages: May bind and stabilize microtubules during myotubes formation.
messages: Z line

9915:NAALADL1
gene id: 9915:NAALADL1
uniprot id: A0A6P5AVA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9915:DNAJA4
gene id: 9915:DNAJA4
uniprot id: A0A6P5DL55
names: Subcellular Location Annotation
messages: Membrane

9915:GHSR
gene id: 9915:GHSR
uniprot id: A0A6P5BRM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

9915:MRPL15
gene id: 9915:MRPL15
uniprot id: A0A6P5CTW6
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

9915:CACFD1
gene id: 9915:CACFD1
uniprot id: A0A6P5CML4
uniprot id: A0A6P5CPC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

9915:OAT
gene id: 9915:OAT
uniprot id: A0A6P5B7Q0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

9915:PPEF1
gene id: 9915:PPEF1
uniprot id: A0A6P5B4Z2
names: Similarity
messages: Belongs to the PPP phosphatase family.

9915:LOC109564494
gene id: 9915:LOC109564494
uniprot id: A0A6P5CCS6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CACNG6
gene id: 9915:CACNG6
uniprot id: A0A6P5DD41
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.

9915:LOC109558817
gene id: 9915:LOC109558817
uniprot id: A0A6P5BBR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:GAL3ST4
gene id: 9915:GAL3ST4
uniprot id: A0A6P5DYV5
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

9915:ABCC9
gene id: 9915:ABCC9
uniprot id: A0A6P5BB24
names: Subunit
messages: Interacts with KCNJ11.

9915:ACTN4
gene id: 9915:ACTN4
uniprot id: A0A6P5D9C1
uniprot id: A0A6P5D9E6
uniprot id: A0A6P5D9J2
uniprot id: A0A6P5D9J9
uniprot id: A0A6P5DBC0
uniprot id: A0A6P5DBD3
uniprot id: A0A6P5DBR7
uniprot id: A0A6P5DCT6
uniprot id: A0A6P5DCU4
names: Similarity
messages: Belongs to the alpha-actinin family.

9915:PTGS2
gene id: 9915:PTGS2
uniprot id: A0A6P5D4S1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane
messages: Nucleus inner membrane
messages: Nucleus outer membrane

9915:SQLE
gene id: 9915:SQLE
uniprot id: A0A6P5CU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

9915:SSH1
gene id: 9915:SSH1
uniprot id: A0A6P5D581
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

9915:BOP1
gene id: 9915:BOP1
uniprot id: A0A6P5CU69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the PeBoW complex, composed of BOP1, PES1 and WDR12. Within the PeBoW complex BOP1 interacts directly with PES1 and WDR12. The PeBoW complex also associates with the 66S pre-ribosome.
messages: Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

9915:LYRM2
gene id: 9915:LYRM2
uniprot id: A0A6P5CCS5
names: Similarity
messages: Belongs to the complex I LYR family.

9915:PSMA4
gene id: 9915:PSMA4
uniprot id: A0A6P5DQE3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex).
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9915:FAM210A
gene id: 9915:FAM210A
uniprot id: A0A6P5DVX3
names: Similarity
messages: Belongs to the FAM210 family.

9915:RSRP1
gene id: 9915:RSRP1
uniprot id: A0A6P5DEM0
names: Similarity
messages: Belongs to the RSRP family.

9915:JPH3
gene id: 9915:JPH3
uniprot id: A0A6P5DFG0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9915:TUBB1
gene id: 9915:TUBB1
uniprot id: A0A6P5CQZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9915:PLD2
gene id: 9915:PLD2
uniprot id: A0A6P5DHH2
names: Similarity
messages: Belongs to the phospholipase D family.

9915:LOC109561773
gene id: 9915:LOC109561773
uniprot id: A0A6P5C3H9
uniprot id: A0A6P5C4H7
names: Subcellular Location Annotation
messages: Membrane

9915:DNAJC16
gene id: 9915:DNAJC16
uniprot id: A0A6P5D1K6
uniprot id: A0A6P5D3I0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109559142
gene id: 9915:LOC109559142
uniprot id: A0A6P5BSY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9915:PHKG2
gene id: 9915:PHKG2
uniprot id: A0A6P5E195
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

9915:AGMAT
gene id: 9915:AGMAT
uniprot id: A0A6P5D145
uniprot id: A0A6P5D4T9
names: Similarity
messages: Belongs to the arginase family.
messages: Belongs to the arginase family. Agmatinase subfamily.

9915:CCL28
gene id: 9915:CCL28
uniprot id: A0A6P5DKK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:EPGN
gene id: 9915:EPGN
uniprot id: A0A6P5BYU4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109557979
gene id: 9915:LOC109557979
uniprot id: A0A6P5BRH3
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

9915:LOC109577723
gene id: 9915:LOC109577723
uniprot id: A0A6P5DYP8
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109574112
gene id: 9915:LOC109574112
uniprot id: A0A6P5DJU0
names: Subcellular Location Annotation
messages: Nucleus

9915:TMEM38A
gene id: 9915:TMEM38A
uniprot id: A0A6P5C2P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

9915:CRIPT
gene id: 9915:CRIPT
uniprot id: A0A6P5CI14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRIPT family.
messages: Cytoplasm

9915:HOXC5
gene id: 9915:HOXC5
uniprot id: A0A6P5BFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:MMAB
gene id: 9915:MMAB
uniprot id: A0A6P5D771
uniprot id: A0A6P5D854
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

9915:LOC109574698
gene id: 9915:LOC109574698
uniprot id: A0A6P5DJ56
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

9915:BPIFA1
gene id: 9915:BPIFA1
uniprot id: A0A6P5CSH6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
messages: Monomer. Interacts (via N-terminus) with SCNN1B, a subunit of the heterotrimeric epithelial sodium channel (ENaC); this inhibits proteolytic activation of ENaC.
messages: Secreted

9915:COG8
gene id: 9915:COG8
uniprot id: A0A6P5D9F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

9915:ZSCAN4
gene id: 9915:ZSCAN4
uniprot id: A0A6P5D6Y3
names: Subcellular Location Annotation
messages: Nucleus

9915:TSPAN9
gene id: 9915:TSPAN9
uniprot id: A0A6P5BVH3
uniprot id: A0A6P5BVH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:TMEM106A
gene id: 9915:TMEM106A
uniprot id: A0A6P5DIA0
names: Similarity
messages: Belongs to the TMEM106 family.

9915:CAPN12
gene id: 9915:CAPN12
uniprot id: A0A6P5D9W8
names: Similarity
messages: Belongs to the peptidase C2 family.

9915:TGM2
gene id: 9915:TGM2
uniprot id: A0A6P5CT08
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

9915:WNT7A
gene id: 9915:WNT7A
uniprot id: A0A6P5DS65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:CITED4
gene id: 9915:CITED4
uniprot id: A0A6P5BPK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

9915:LOC109556091
gene id: 9915:LOC109556091
uniprot id: A0A6P5BHH8
uniprot id: A0A6P5BNW1
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:LOC109561188
gene id: 9915:LOC109561188
uniprot id: A0A6P5C0X5
names: Subcellular Location Annotation
messages: Nucleus

9915:ANTXR1
gene id: 9915:ANTXR1
uniprot id: A0A6P5CKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

9915:LOC109562637
gene id: 9915:LOC109562637
uniprot id: A0A6P5C6M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:IMPACT
gene id: 9915:IMPACT
uniprot id: A0A6P5DVA7
names: Similarity
messages: Belongs to the IMPACT family.

9915:B4GALT6
gene id: 9915:B4GALT6
uniprot id: A0A6P5DVY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9915:AMOT
gene id: 9915:AMOT
uniprot id: A0A6P5AX55
uniprot id: A0A6P5B2X8
uniprot id: A0A6P5BEY3
uniprot id: A0A6P5BLL3
names: Similarity
messages: Belongs to the angiomotin family.

9915:TLCD2
gene id: 9915:TLCD2
uniprot id: A0A6P5DJ10
names: Subcellular Location Annotation
messages: Membrane

9915:RNF114
gene id: 9915:RNF114
uniprot id: A0A6P5CTG2
names: Subunit
messages: Interacts with XAF1, the interaction increases XAF1 stability and proapoptotic effects, and may regulate IFN signaling.

9915:KCNQ3
gene id: 9915:KCNQ3
uniprot id: A0A6P5CVW5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:KCNC1
gene id: 9915:KCNC1
uniprot id: A0A6P5D1X2
names: Subcellular Location Annotation
messages: Membrane

9915:EPS8
gene id: 9915:EPS8
uniprot id: A0A6P5BV04
names: Similarity
messages: Belongs to the EPS8 family.

9915:ULK1
gene id: 9915:ULK1
uniprot id: A0A6P5D5K6
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
messages: Serine/threonine-protein kinase involved in autophagy in response to starvation.

9915:S1PR3
gene id: 9915:S1PR3
uniprot id: A0A6P5C9R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:ST3GAL5
gene id: 9915:ST3GAL5
uniprot id: A0A6P5CKY2
uniprot id: A0A6P5CLV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:TMEM41A
gene id: 9915:TMEM41A
uniprot id: A0A6P5BAX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

9915:RPGRIP1L
gene id: 9915:RPGRIP1L
uniprot id: A0A6P5DEK2
names: Similarity
messages: Belongs to the RPGRIP1 family.

9915:TNFAIP3
gene id: 9915:TNFAIP3
uniprot id: A0A6P5CBQ6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:PDCD10
gene id: 9915:PDCD10
uniprot id: A0A6P5BS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

9915:BEST2
gene id: 9915:BEST2
uniprot id: A0A6P5C018
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Membrane

9915:TMEM150C
gene id: 9915:TMEM150C
uniprot id: A0A6P5BZ26
names: Subcellular Location Annotation
messages: Membrane

9915:CENPL
gene id: 9915:CENPL
uniprot id: A0A6P5D687
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-L/IML3 family.
messages: Nucleus

9915:PTPRB
gene id: 9915:PTPRB
uniprot id: A0A6P5BE61
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

9915:JRKL
gene id: 9915:JRKL
uniprot id: A0A6P5D2A5
names: Subcellular Location Annotation
messages: Nucleus

9915:ZDHHC9
gene id: 9915:ZDHHC9
uniprot id: A0A6P5BFY7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:LOC109563598
gene id: 9915:LOC109563598
uniprot id: A0A6P5CAB1
names: Subcellular Location Annotation
messages: Membrane

9915:PAX6
gene id: 9915:PAX6
uniprot id: A0A6P5CXP9
uniprot id: A0A6P5CXQ4
uniprot id: A0A6P5CXS5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:DKK3
gene id: 9915:DKK3
uniprot id: A0A6P5CZN4
names: Similarity
messages: Belongs to the dickkopf family.

9915:TP53INP1
gene id: 9915:TP53INP1
uniprot id: A0A6P5CUP4
uniprot id: A0A6P5CWX7
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

9915:SVIL
gene id: 9915:SVIL
uniprot id: A0A6P5CSR0
names: Similarity
messages: Belongs to the villin/gelsolin family.

9915:LOC109571835
gene id: 9915:LOC109571835
uniprot id: A0A6P5D919
names: Subcellular Location Annotation
messages: Membrane

9915:L1CAM
gene id: 9915:L1CAM
uniprot id: A0A6P5B4K0
uniprot id: A0A6P5BMF2
names: Similarity
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.

9915:MTMR2
gene id: 9915:MTMR2
uniprot id: A0A6P5CYY1
uniprot id: A0A6P5D1P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

9915:IMPDH2
gene id: 9915:IMPDH2
uniprot id: A0A6P5DPC7
uniprot id: A0A6P5DRH4
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.
messages: Nucleus

9915:LOC109565324
gene id: 9915:LOC109565324
uniprot id: A0A6P5CH06
uniprot id: A0A6P5CIK7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9915:TOP3A
gene id: 9915:TOP3A
uniprot id: A0A6P5DGX0
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9915:SAP130
gene id: 9915:SAP130
uniprot id: A0A6P5CF22
uniprot id: A0A6P5CG82
uniprot id: A0A6P5CGI3
uniprot id: A0A6P5CGK2
uniprot id: A0A6P5CGK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAP130 family.
messages: Nucleus

9915:SYCE1
gene id: 9915:SYCE1
uniprot id: A0A6P5AWK6
names: Similarity
messages: Belongs to the SYCE family.

9915:B3GALT4
gene id: 9915:B3GALT4
uniprot id: A0A6P5DUR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:TLR5
gene id: 9915:TLR5
uniprot id: A7YK55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9915:TMPRSS13
gene id: 9915:TMPRSS13
uniprot id: A0A6P5CUM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:NUDT6
gene id: 9915:NUDT6
uniprot id: A0A6P5D3U4
uniprot id: A0A6P5D523
uniprot id: A0A6P5D675
uniprot id: A0A6P5D7Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Nudix hydrolase family.
messages: Cytoplasm
messages: May contribute to the regulation of cell proliferation.
messages: Mitochondrion
messages: Monomer and homodimer.
messages: Nucleus

9915:RAD9A
gene id: 9915:RAD9A
uniprot id: A0A6P5BCT8
names: Similarity
messages: Belongs to the rad9 family.

9915:ANK1
gene id: 9915:ANK1
uniprot id: A0A6P5AQD2
uniprot id: A0A6P5B8W7
uniprot id: A0A6P5BHP4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

9915:EIF5A2
gene id: 9915:EIF5A2
uniprot id: A0A6P5BRR6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-5A family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.
messages: mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Critical for the efficient synthesis of peptide bonds between consecutive proline residues. Can resolve ribosomal stalling caused by consecutive prolines during translation. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis.

9915:GPS1
gene id: 9915:GPS1
uniprot id: A0A6P5DFP4
uniprot id: A0A6P5DI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN1 family.
messages: Cytoplasm
messages: Nucleus

9915:FAM45A
gene id: 9915:FAM45A
uniprot id: A0A6P5AN92
uniprot id: A0A6P5BG09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

9915:SLC24A1
gene id: 9915:SLC24A1
uniprot id: A0A6P5CCZ7
uniprot id: A0A6P5CD02
uniprot id: A0A6P5CDD2
uniprot id: A0A6P5CE48
uniprot id: A0A6P5CEJ0
uniprot id: A0A6P5CF92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

9915:C11H9orf116
gene id: 9915:C11H9orf116
uniprot id: A0A6P5CKT6
uniprot id: A0A6P5CMP2
uniprot id: A0A6P5CPF1
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CFAP53, ODAD1 and ODAD3; the interactions link the outer dynein arms docking complex (ODA-DC) to the internal microtubule inner proteins (MIP) in cilium axoneme.
messages: cilium axoneme

9915:SLC45A2
gene id: 9915:SLC45A2
uniprot id: A0A6P5DLG3
names: Subcellular Location Annotation
messages: Membrane

9915:SULF1
gene id: 9915:SULF1
uniprot id: A0A6P5CUT4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:LOC109558136
gene id: 9915:LOC109558136
uniprot id: A0A6P5BRP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RNF121
gene id: 9915:RNF121
uniprot id: A0A6P5CWQ8
uniprot id: A0A6P5CY66
uniprot id: A0A6P5CZ25
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109557897
gene id: 9915:LOC109557897
uniprot id: A0A6P5BL92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9915:NAXE
gene id: 9915:NAXE
uniprot id: A0A6P5BH80
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis.
messages: Homodimer. Interacts with APOA1 and APOA2.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Secreted
messages: Undergoes physiological phosphorylation during sperm capacitation, downstream to PKA activation.

9915:OSBPL8
gene id: 9915:OSBPL8
uniprot id: A0A6P5BMK4
names: Similarity
messages: Belongs to the OSBP family.

9915:UBE2S
gene id: 9915:UBE2S
uniprot id: A0A6P5DEV3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:XYLT1
gene id: 9915:XYLT1
uniprot id: A0A6P5DWD0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

9915:LOC109570660
gene id: 9915:LOC109570660
uniprot id: A0A6P5D2N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

9915:RAPGEF6
gene id: 9915:RAPGEF6
uniprot id: A0A6P5C4R0
names: Similarity
messages: Belongs to the RAPGEF2 family.

9915:RPL19
gene id: 9915:RPL19
uniprot id: A0A6P5DI26
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

9915:NSUN7
gene id: 9915:NSUN7
uniprot id: A0A6P5BY09
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:DYNLRB1
gene id: 9915:DYNLRB1
uniprot id: A0A6P5CQR3
uniprot id: A0A6P5CRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9915:LOC109568077
gene id: 9915:LOC109568077
uniprot id: A0A6P5CS70
uniprot id: A0A6P5CTG6
uniprot id: A0A6P5CVN1
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:MARCO
gene id: 9915:MARCO
uniprot id: A0A6P5CTK4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109569191
gene id: 9915:LOC109569191
uniprot id: A0A6P5CVK4
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9915:LEO1
gene id: 9915:LEO1
uniprot id: A0A6P5CES4
uniprot id: A0A6P5CHK6
names: Similarity
messages: Belongs to the LEO1 family.

9915:LOC109575294
gene id: 9915:LOC109575294
uniprot id: A0A6P5DLZ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:HSPB9
gene id: 9915:HSPB9
uniprot id: A0A6P5DGW4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

9915:HAUS3
gene id: 9915:HAUS3
uniprot id: A0A6P5BZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

9915:UMOD
gene id: 9915:UMOD
uniprot id: A0A6P5E142
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Cell membrane
messages: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: cilium membrane

9915:LOC109568970
gene id: 9915:LOC109568970
uniprot id: A0A6P5CV13
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109573574
gene id: 9915:LOC109573574
uniprot id: A0A6P5DG60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RUNX3
gene id: 9915:RUNX3
uniprot id: A0A6P5DH29
names: Function
names: Subcellular Location Annotation
messages: Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.
messages: Nucleus

9915:HTR1A
gene id: 9915:HTR1A
uniprot id: A0A6P5DKL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.
messages: Membrane
messages: dendrite

9915:CDKN2AIPNL
gene id: 9915:CDKN2AIPNL
uniprot id: A0A6P5C4F4
uniprot id: A0A6P5C4V2
uniprot id: A0A6P5C5T9
names: Similarity
messages: Belongs to the CARF family.

9915:LOC109558994
gene id: 9915:LOC109558994
uniprot id: A0A6P5BF90
uniprot id: A0A6P5BSK6
names: Subcellular Location Annotation
messages: cytoskeleton

9915:TMEM14A
gene id: 9915:TMEM14A
uniprot id: A0A6P5DT43
uniprot id: A0A6P5DUH2
uniprot id: A0A6P5DXA3
uniprot id: A0A6P5DXB3
names: Similarity
messages: Belongs to the TMEM14 family.

9915:PMF1
gene id: 9915:PMF1
uniprot id: A0A6P5B8I8
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

9915:NKX3-1
gene id: 9915:NKX3-1
uniprot id: A0A6P5C8A6
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109555610
gene id: 9915:LOC109555610
uniprot id: A0A6P5BGK0
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9915:C25H16orf91
gene id: 9915:C25H16orf91
uniprot id: A0A6P5DZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCSMST1 family.
messages: Membrane

9915:LOC109554073
gene id: 9915:LOC109554073
uniprot id: A0A6P5BJ21
uniprot id: A0A6P5BJC4
names: Similarity
messages: Belongs to the RASGRP family.

9915:CCNE1
gene id: 9915:CCNE1
uniprot id: A0A6P5DBN5
uniprot id: A0A6P5DEU8
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

9915:SLCO4C1
gene id: 9915:SLCO4C1
uniprot id: A0A6P5C5X0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:DDX55
gene id: 9915:DDX55
uniprot id: A0A6P5D682
names: Similarity
messages: Belongs to the DEAD box helicase family.

9915:TCP11L1
gene id: 9915:TCP11L1
uniprot id: A0A6P5CVU0
uniprot id: A0A6P5CZ90
names: Similarity
messages: Belongs to the TCP11 family.

9915:PDYN
gene id: 9915:PDYN
uniprot id: A0A6P5CQM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the opioid neuropeptide precursor family.
messages: Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A(1-13) has a typical opiod activity, it is 700 times more potent than Leu-enkephalin.
messages: Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.
messages: Leumorphin has a typical opiod activity and may have anti-apoptotic effect.
messages: Secreted

9915:PEX5
gene id: 9915:PEX5
uniprot id: A0A6P5BC59
uniprot id: A0A6P5BEY2
uniprot id: A0A6P5BSC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

9915:GNB1
gene id: 9915:GNB1
uniprot id: A0A6P5D387
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

9915:COL4A4
gene id: 9915:COL4A4
uniprot id: A0A6P5DP96
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.
messages: basement membrane

9915:LOC109558688
gene id: 9915:LOC109558688
uniprot id: A0A6P5BEJ2
names: Similarity
messages: Belongs to the intermediate filament family.

9915:TRAPPC3
gene id: 9915:TRAPPC3
uniprot id: A0A6P5B955
uniprot id: A0A6P5BPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

9915:SLC9A2
gene id: 9915:SLC9A2
uniprot id: A0A6P5CJH3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

9915:GLT6D1
gene id: 9915:GLT6D1
uniprot id: A0A6P5CJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9915:GRM3
gene id: 9915:GRM3
uniprot id: A0A6P5BB65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

9915:ALG11
gene id: 9915:ALG11
uniprot id: A0A6P5CN45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly.

9915:LOC109569378
gene id: 9915:LOC109569378
uniprot id: A0A6P5CYQ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NAALAD2
gene id: 9915:NAALAD2
uniprot id: A0A6P5AVS0
uniprot id: A0A6P5BKT2
uniprot id: A0A6P5BKU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

9915:CNDP2
gene id: 9915:CNDP2
uniprot id: A0A6P5DVK7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9915:CLPS
gene id: 9915:CLPS
uniprot id: A0A6P5DRF8
uniprot id: A0A6P5DVC5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
messages: Enterostatin has a biological activity as a satiety signal.
messages: Forms a 1:1 stoichiometric complex with pancreatic lipase.
messages: Secreted

9915:CCL17
gene id: 9915:CCL17
uniprot id: A0A6P5D9M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:PHF19
gene id: 9915:PHF19
uniprot id: A0A6P5C9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

9915:GSK3B
gene id: 9915:GSK3B
uniprot id: A0A6P5E0Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

9915:TUBB4A
gene id: 9915:TUBB4A
uniprot id: A0A6P5C417
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9915:LIN7A
gene id: 9915:LIN7A
uniprot id: A0A6P5BSI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the lin-7 family.
messages: Cell membrane
messages: Lateral cell membrane
messages: Membrane
messages: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells.
messages: Postsynaptic density membrane
messages: tight junction

9915:RNASE12
gene id: 9915:RNASE12
uniprot id: A0A6P5CE65
uniprot id: A0A6P5CFA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:EIF4G2
gene id: 9915:EIF4G2
uniprot id: A0A6P5CUP1
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

9915:SAP30
gene id: 9915:SAP30
uniprot id: A0A6P5C7C6
names: Similarity
messages: Belongs to the SAP30 family.

9915:XRN2
gene id: 9915:XRN2
uniprot id: A0A6P5CT12
uniprot id: A0A6P5CTC2
uniprot id: A0A6P5CUG6
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

9915:EPHB6
gene id: 9915:EPHB6
uniprot id: A0A6P5BCQ0
names: Subcellular Location Annotation
messages: Membrane

9915:KCNG3
gene id: 9915:KCNG3
uniprot id: A0A6P5CHX7
names: Subcellular Location Annotation
messages: Membrane

9915:ISL1
gene id: 9915:ISL1
uniprot id: A0A6P5DJG9
names: Subcellular Location Annotation
messages: Nucleus

9915:ASPH
gene id: 9915:ASPH
uniprot id: A0A6P5CSM7
uniprot id: A0A6P5CSN0
uniprot id: A0A6P5CTN2
uniprot id: A0A6P5CTZ7
uniprot id: A0A6P5CU01
uniprot id: A0A6P5CV35
uniprot id: A0A6P5CW52
uniprot id: A0A6P5CW57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
messages: Membrane

9915:EEF1D
gene id: 9915:EEF1D
uniprot id: A0A6P5CSU5
uniprot id: A0A6P5CWE0
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

9915:OXR1
gene id: 9915:OXR1
uniprot id: A0A6P5CW17
names: Similarity
messages: Belongs to the OXR1 family.

9915:LOC109568913
gene id: 9915:LOC109568913
uniprot id: A0A6P5CYC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM49B
gene id: 9915:FAM49B
uniprot id: A0A6P5CUP8
uniprot id: A0A6P5CW73
uniprot id: A0A6P5CX77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CYRI family.
messages: Interacts with RAC1 (GTP-bound form preferentially).
messages: Membrane

9915:SLC2A1
gene id: 9915:SLC2A1
uniprot id: A0A6P5B8P4
uniprot id: A0A6P5BIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane
messages: Photoreceptor inner segment

9915:PPM1K
gene id: 9915:PPM1K
uniprot id: A0A6P5BXJ3
names: Similarity
messages: Belongs to the PP2C family.

9915:LOC109554026
gene id: 9915:LOC109554026
uniprot id: A0A6P5BIW8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ADGRD1
gene id: 9915:ADGRD1
uniprot id: A0A6P5D588
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:TMEM201
gene id: 9915:TMEM201
uniprot id: A0A6P5D0S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

9915:TNKS2
gene id: 9915:TNKS2
uniprot id: A0A6P5E3E6
names: Function
names: Similarity
messages: Belongs to the ARTD/PARP family.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:APEX1
gene id: 9915:APEX1
uniprot id: A0A6P5CEW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair enzymes AP/ExoA family.
messages: Cytoplasm
messages: Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
messages: Mitochondrion
messages: Nucleus
messages: Probably binds two magnesium or manganese ions per subunit.

9915:SERPINA11
gene id: 9915:SERPINA11
uniprot id: A0A6P5DN03
names: Similarity
messages: Belongs to the serpin family.

9915:ELOVL1
gene id: 9915:ELOVL1
uniprot id: A0A6P5B3Z3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
messages: Endoplasmic reticulum membrane
messages: Interacts with LASS2, TECR and HSD17B12.
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9915:LOC109576090
gene id: 9915:LOC109576090
uniprot id: A0A6P5DNP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPRBP/DCAF1 family.
messages: Nucleus

9915:PRDX6
gene id: 9915:PRDX6
uniprot id: A0A6P5D4F0
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

9915:PTX4
gene id: 9915:PTX4
uniprot id: A0A6P5E0A7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109567039
gene id: 9915:LOC109567039
uniprot id: A0A6P5CR77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9915:SPTBN4
gene id: 9915:SPTBN4
uniprot id: A0A6P5DDU4
names: Similarity
messages: Belongs to the spectrin family.

9915:ZIC3
gene id: 9915:ZIC3
uniprot id: A0A6P5BME4
uniprot id: A0A6P5BMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

9915:GALNT9
gene id: 9915:GALNT9
uniprot id: A0A6P5D346
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:HAL
gene id: 9915:HAL
uniprot id: A0A6P5BTY5
names: Similarity
messages: Belongs to the PAL/histidase family.

9915:PCMT1
gene id: 9915:PCMT1
uniprot id: A0A6P5CCG5
uniprot id: A0A6P5CCU2
uniprot id: A0A6P5CDG4
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

9915:POPDC3
gene id: 9915:POPDC3
uniprot id: A0A6P5CBY0
names: Similarity
messages: Belongs to the popeye family.

9915:TMEM19
gene id: 9915:TMEM19
uniprot id: A0A6P5BSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM19 family.
messages: Membrane

9915:LOC109568942
gene id: 9915:LOC109568942
uniprot id: A0A6P5CXH7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GLMP
gene id: 9915:GLMP
uniprot id: A0A6P5B8D0
uniprot id: A0A6P5BHD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GLMP family.
messages: Interacts (via lumenal domain) with lysosomal protein MFSD1; the interaction starts while both proteins are still in the endoplasmic reticulum and is required for stability and lysosomal localization of MFSD1.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

9915:PER2
gene id: 9915:PER2
uniprot id: A0A6P5BJ01
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:SOD1
gene id: 9915:SOD1
uniprot id: A0A6P5BP41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Nucleus

9915:ITM2C
gene id: 9915:ITM2C
uniprot id: A0A6P5D979
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9915:ERG
gene id: 9915:ERG
uniprot id: A0A6P5C2R7
uniprot id: A0A6P5C2U6
uniprot id: A0A6P5C3M8
uniprot id: A0A6P5C3N8
uniprot id: A0A6P5C3S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:DZIP3
gene id: 9915:DZIP3
uniprot id: A0A6P5D127
uniprot id: A0A6P5D217
uniprot id: A0A6P5D2I5
uniprot id: A0A6P5D2R2
uniprot id: A0A6P5D362
uniprot id: A0A6P5D4X9
names: Subcellular Location Annotation
messages: Cytoplasm

9915:UHRF1
gene id: 9915:UHRF1
uniprot id: A0A6P5C0J1
names: Subcellular Location Annotation
messages: Nucleus

9915:TYROBP
gene id: 9915:TYROBP
uniprot id: A0A6P5DAQ4
uniprot id: B2BBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TYROBP family.
messages: Cell membrane
messages: Membrane

9915:LOC109560923
gene id: 9915:LOC109560923
uniprot id: A0A6P5C0G7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HTT
gene id: 9915:HTT
uniprot id: A0A6P5C025
uniprot id: A0A6P5C0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

9915:WEE2
gene id: 9915:WEE2
uniprot id: A0A6P5BRL6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

9915:CNIH3
gene id: 9915:CNIH3
uniprot id: A0A6P5D2Q8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9915:ZNF274
gene id: 9915:ZNF274
uniprot id: A0A6P5D6A1
uniprot id: A0A6P5D6A5
uniprot id: A0A6P5D7H2
uniprot id: A0A6P5D8G3
uniprot id: A0A6P5D9R6
names: Subcellular Location Annotation
messages: Nucleus

9915:KCNK15
gene id: 9915:KCNK15
uniprot id: A0A6P5CRV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9915:TNFRSF19
gene id: 9915:TNFRSF19
uniprot id: A0A6P5CLR2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TMEM129
gene id: 9915:TMEM129
uniprot id: A0A6P5BZL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

9915:NSUN4
gene id: 9915:NSUN4
uniprot id: A0A6P5B879
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

9915:MFN1
gene id: 9915:MFN1
uniprot id: A0A6P5BD43
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

9915:POFUT1
gene id: 9915:POFUT1
uniprot id: A0A6P5CNZ1
uniprot id: A0A6P5CQ25
uniprot id: A0A6P5CQL4
uniprot id: A0A6P5CSF7
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

9915:LOC109570251
gene id: 9915:LOC109570251
uniprot id: A0A6P5CZW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Belongs to the intercrine gamma family.
messages: Secreted

9915:GLYATL3
gene id: 9915:GLYATL3
uniprot id: A0A6P5DY36
names: Similarity
messages: Belongs to the glycine N-acyltransferase family.

9915:IL5
gene id: 9915:IL5
uniprot id: B5LVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-5 family.
messages: Homodimer; disulfide-linked. Interacts with IL5RA. Interacts with CSF2RB.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation (By similarity). Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Acts also on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively.
messages: Secreted

9915:PLCB1
gene id: 9915:PLCB1
uniprot id: A0A6P5CS81
uniprot id: A0A6P5CT49
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9915:LOC109554668
gene id: 9915:LOC109554668
uniprot id: A0A6P5AVW3
names: Similarity
messages: Belongs to the S-100 family.

9915:ERRFI1
gene id: 9915:ERRFI1
uniprot id: A0A6P5D1B5
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

9915:ATP10B
gene id: 9915:ATP10B
uniprot id: A0A6P5C640
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

9915:LOC109574003
gene id: 9915:LOC109574003
uniprot id: A0A6P5DG84
uniprot id: A0A6P5DHS3
uniprot id: A0A6P5DIM0
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PQLC3
gene id: 9915:PQLC3
uniprot id: A0A6P5CMY3
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109562312
gene id: 9915:LOC109562312
uniprot id: A0A6P5DF21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits, encoded in the mitochondrial DNA, and 11 supernumerary subunits, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

9915:ATG13
gene id: 9915:ATG13
uniprot id: A0A6P5CYI8
uniprot id: A0A6P5CYR1
uniprot id: A0A6P5CYR6
uniprot id: A0A6P5D0A6
uniprot id: A0A6P5D158
uniprot id: A0A6P5D162
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy factor required for autophagosome formation and mitophagy. Target of the TOR kinase signaling pathway that regulates autophagy through the control of the phosphorylation status of ATG13 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex. Through its regulation of ULK1 activity, plays a role in the regulation of the kinase activity of mTORC1 and cell proliferation.
messages: Belongs to the ATG13 family. Metazoan subfamily.
messages: Preautophagosomal structure

9915:VKORC1
gene id: 9915:VKORC1
uniprot id: A0A6P5DYB1
uniprot id: A0A6P5E1T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:CYGB
gene id: 9915:CYGB
uniprot id: A0A6P5DCT4
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109573015
gene id: 9915:LOC109573015
uniprot id: A0A6P5DF73
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.

9915:LOC109553136
gene id: 9915:LOC109553136
uniprot id: A0A6P5BGL2
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:LOC109565431
gene id: 9915:LOC109565431
uniprot id: A0A6P5CH04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-2-microglobulin family.
messages: Secreted

9915:CDC42EP2
gene id: 9915:CDC42EP2
uniprot id: A0A6P5B1J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system
messages: Probably involved in the organization of the actin cytoskeleton.
messages: cytoskeleton

9915:FEZ2
gene id: 9915:FEZ2
uniprot id: A0A6P5CHR5
uniprot id: A0A6P5CJY0
names: Similarity
messages: Belongs to the zygin family.

9915:IRF2BP1
gene id: 9915:IRF2BP1
uniprot id: A0A6P5DCZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

9915:MMP9
gene id: 9915:MMP9
uniprot id: A0A6P5CS31
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M10A family.
messages: Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with LCN2. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.
messages: extracellular matrix

9915:LOC109565300
gene id: 9915:LOC109565300
uniprot id: A0A6P5CG74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

9915:DGKG
gene id: 9915:DGKG
uniprot id: A0A6P5BAT8
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:GJD4
gene id: 9915:GJD4
uniprot id: A0A6P5CQ42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:LOC109577677
gene id: 9915:LOC109577677
uniprot id: A0A6P5DY55
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109564320
gene id: 9915:LOC109564320
uniprot id: A0A6P5CD52
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109567803
gene id: 9915:LOC109567803
uniprot id: A0A6P5CQQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

9915:G6PC2
gene id: 9915:G6PC2
uniprot id: A0A6P5DQZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9915:PADI3
gene id: 9915:PADI3
uniprot id: A0A6P5DX53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9915:MRPL13
gene id: 9915:MRPL13
uniprot id: A0A6P5CUS4
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

9915:LOC109565883
gene id: 9915:LOC109565883
uniprot id: A0A6P5CJH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PPP6C
gene id: 9915:PPP6C
uniprot id: A0A6P5CLM0
names: Similarity
messages: Belongs to the PPP phosphatase family.

9915:LOC109557006
gene id: 9915:LOC109557006
uniprot id: A0A6P5BAL5
names: Similarity
messages: Belongs to the LCE family.

9915:HS3ST2
gene id: 9915:HS3ST2
uniprot id: A0A6P5E0U2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:WIPI2
gene id: 9915:WIPI2
uniprot id: A0A6P5E2V4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

9915:CRYZ
gene id: 9915:CRYZ
uniprot id: A0A6P5BNY6
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9915:UBE2H
gene id: 9915:UBE2H
uniprot id: A0A6P5BR11
uniprot id: A0A6P5BR39
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:LOC109571090
gene id: 9915:LOC109571090
uniprot id: A0A6P5D7F0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains (PubMed:6504138, PubMed:2207090, PubMed:7704569). A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers (PubMed:6504138, PubMed:2207090, PubMed:7704569). Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin (PubMed:6504138, PubMed:2207090, PubMed:7704569).
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

9915:MSTO1
gene id: 9915:MSTO1
uniprot id: A0A6P5BHJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

9915:LOC109578619
gene id: 9915:LOC109578619
uniprot id: A0A6P5DYY4
uniprot id: A0A6P5E2E8
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

9915:SCN9A
gene id: 9915:SCN9A
uniprot id: A0A6P5CNY0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9915:ZCCHC17
gene id: 9915:ZCCHC17
uniprot id: A0A6P5DBP1
names: Subcellular Location Annotation
messages: nucleolus

9915:KCNK3
gene id: 9915:KCNK3
uniprot id: A0A6P5CGJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9915:ATP6V1H
gene id: 9915:ATP6V1H
uniprot id: A0A6P5CTZ5
uniprot id: A0A6P5CWH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

9915:JRK
gene id: 9915:JRK
uniprot id: A0A6P5CVF6
names: Subcellular Location Annotation
messages: Nucleus

9915:POLR3K
gene id: 9915:POLR3K
uniprot id: A0A6P5E3E1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

9915:SIX5
gene id: 9915:SIX5
uniprot id: A0A6P5DAZ4
names: Subcellular Location Annotation
messages: Nucleus

9915:LYPLA2
gene id: 9915:LYPLA2
uniprot id: A0A6P5DFL8
uniprot id: A0A6P5DFP0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

9915:RPL37A
gene id: 9915:RPL37A
uniprot id: A0A6P5D1P0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

9915:AZGP1
gene id: 9915:AZGP1
uniprot id: A0A6P5DWD5
names: Similarity
messages: Belongs to the MHC class I family.

9915:LOC109555782
gene id: 9915:LOC109555782
uniprot id: A0A6P5B5R2
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:SLC15A4
gene id: 9915:SLC15A4
uniprot id: A0A6P5D721
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

9915:LOC109563715
gene id: 9915:LOC109563715
uniprot id: A0A6P5CAU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:CNOT3
gene id: 9915:CNOT3
uniprot id: A0A6P5D759
uniprot id: A0A6P5DAV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in metabolic regulation; may be involved in recruitment of the CCR4-NOT complex to deadenylation target mRNAs involved in energy metabolism. Involved in mitotic progression and regulation of the spindle assembly checkpoint by regulating the stability of MAD1L1 mRNA. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation; the repressive function may involve histone deacetylases. Involved in the maintenance of embryonic stem (ES) cell identity.
messages: Nucleus
messages: P-body

9915:LOC109575968
gene id: 9915:LOC109575968
uniprot id: B9TUC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:DLD
gene id: 9915:DLD
uniprot id: A0A6P5B728
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.
messages: acrosome
messages: flagellum

9915:LOC109572736
gene id: 9915:LOC109572736
uniprot id: A0A6P5DCY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

9915:LOC109554814
gene id: 9915:LOC109554814
uniprot id: A0A6P5BL38
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

9915:PTH1R
gene id: 9915:PTH1R
uniprot id: A0A6P5DRW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9915:NKAIN1
gene id: 9915:NKAIN1
uniprot id: A0A6P5DBV3
uniprot id: A0A6P5DC87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

9915:TBPL2
gene id: 9915:TBPL2
uniprot id: A0A6P5CCM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

9915:LOC109569947
gene id: 9915:LOC109569947
uniprot id: A0A6P5CZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC27A1
gene id: 9915:SLC27A1
uniprot id: A0A6P5C1H5
uniprot id: A0A6P5C2J6
uniprot id: A0A6P5C2K1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:SGK3
gene id: 9915:SGK3
uniprot id: A0A6P5CTX6
uniprot id: A0A6P5CUW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cytoplasm

9915:PSMB11
gene id: 9915:PSMB11
uniprot id: A0A6P5CE22
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9915:LOC109561005
gene id: 9915:LOC109561005
uniprot id: A0A6P5C0M0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RARA
gene id: 9915:RARA
uniprot id: A0A6P5DIB1
uniprot id: A0A6P5DJU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:PRKAB1
gene id: 9915:PRKAB1
uniprot id: A0A6P5D7I9
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

9915:CAD
gene id: 9915:CAD
uniprot id: A0A6P5CKC0
uniprot id: A0A6P5CLK8
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

9915:LOC109570142
gene id: 9915:LOC109570142
uniprot id: A0A6P5D3C9
names: Subcellular Location Annotation
messages: Nucleus

9915:HTR7
gene id: 9915:HTR7
uniprot id: A0A6P5APQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:PTK6
gene id: 9915:PTK6
uniprot id: A0A6P5CPI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9915:TDP2
gene id: 9915:TDP2
uniprot id: A0A6P5DSE5
names: Subcellular Location Annotation
messages: PML body

9915:DDI1
gene id: 9915:DDI1
uniprot id: A0A6P5CZL1
names: Similarity
messages: Belongs to the DDI1 family.

9915:AJAP1
gene id: 9915:AJAP1
uniprot id: A0A6P5D2P8
names: Subcellular Location Annotation
messages: Membrane

9915:SLC15A3
gene id: 9915:SLC15A3
uniprot id: A0A6P5BKH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

9915:LOC109566380
gene id: 9915:LOC109566380
uniprot id: A0A6P5CKS3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

9915:DRAXIN
gene id: 9915:DRAXIN
uniprot id: A0A6P5D5S7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway.
messages: Interacts with LRP6.
messages: Secreted

9915:TRIM46
gene id: 9915:TRIM46
uniprot id: A0A6P5ARE3
uniprot id: A0A6P5B9Z6
uniprot id: A0A6P5BI05
uniprot id: A0A6P5BID4
names: Subcellular Location Annotation
messages: cytoskeleton

9915:TLR4
gene id: 9915:TLR4
uniprot id: A0A6P5CA83
uniprot id: A0A6P5CAE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

9915:LOC109566452
gene id: 9915:LOC109566452
uniprot id: A0A6P5CMC1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558421
gene id: 9915:LOC109558421
uniprot id: A0A6P5BE74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ERAP2
gene id: 9915:ERAP2
uniprot id: A0A6P5C5Y0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9915:FOXA3
gene id: 9915:FOXA3
uniprot id: A0A6P5DBU1
names: Subcellular Location Annotation
messages: Nucleus

9915:MMD2
gene id: 9915:MMD2
uniprot id: A0A6P5DWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

9915:NR5A1
gene id: 9915:NR5A1
uniprot id: A0A6P5CLK7
uniprot id: A0A6P5CNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

9915:NOP14
gene id: 9915:NOP14
uniprot id: A0A6P5BZZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

9915:KLHL21
gene id: 9915:KLHL21
uniprot id: A0A6P5D417
names: Subcellular Location Annotation
messages: spindle

9915:DPY19L3
gene id: 9915:DPY19L3
uniprot id: A0A6P5DEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9915:TMEM88
gene id: 9915:TMEM88
uniprot id: A0A6P5DHQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM88 family.
messages: Membrane

9915:TCP11L2
gene id: 9915:TCP11L2
uniprot id: A0A6P5BUC6
names: Similarity
messages: Belongs to the TCP11 family.

9915:LAMP5
gene id: 9915:LAMP5
uniprot id: A0A6P5CSY8
uniprot id: A0A6P5CU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

9915:ADCY4
gene id: 9915:ADCY4
uniprot id: A0A6P5CCY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9915:LOC109555754
gene id: 9915:LOC109555754
uniprot id: A0A6P5BN04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:CNIH2
gene id: 9915:CNIH2
uniprot id: A0A6P5BJ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

9915:DLX1
gene id: 9915:DLX1
uniprot id: A0A6P5DQT1
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109569166
gene id: 9915:LOC109569166
uniprot id: A0A6P5CVG4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PPP1R2
gene id: 9915:PPP1R2
uniprot id: A0A6P5B8E9
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

9915:STK11IP
gene id: 9915:STK11IP
uniprot id: A0A6P5D5L1
uniprot id: A0A6P5D6L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

9915:QARS
gene id: 9915:QARS
uniprot id: A0A6P5DNK7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9915:ADPRHL2
gene id: 9915:ADPRHL2
uniprot id: A0A6P5B4H9
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

9915:FOXD2
gene id: 9915:FOXD2
uniprot id: A0A6P5B3E1
names: Subcellular Location Annotation
messages: Nucleus

9915:CCDC22
gene id: 9915:CCDC22
uniprot id: A0A6P5B3S0
uniprot id: A0A6P5BFL3
names: Similarity
messages: Belongs to the CCDC22 family.

9915:LOC109574090
gene id: 9915:LOC109574090
uniprot id: A0A6P5DJ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

9915:SERINC3
gene id: 9915:SERINC3
uniprot id: A0A6P5CPK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9915:ATP2B4
gene id: 9915:ATP2B4
uniprot id: A0A6P5D1Y7
uniprot id: A0A6P5D3B7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:NOX1
gene id: 9915:NOX1
uniprot id: A0A6P5B2S4
uniprot id: A0A6P5BET4
uniprot id: A0A6P5BLI6
names: Subcellular Location Annotation
messages: Membrane

9915:DNTT
gene id: 9915:DNTT
uniprot id: A0A6P5E0R8
uniprot id: A0A6P5E484
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Nucleus
messages: Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator.

9915:HARBI1
gene id: 9915:HARBI1
uniprot id: A0A6P5CZS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

9915:TSPAN7
gene id: 9915:TSPAN7
uniprot id: A0A6P5AYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:MRPS18C
gene id: 9915:MRPS18C
uniprot id: A0A6P5BZ50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Mitochondrion

9915:GPX8
gene id: 9915:GPX8
uniprot id: A0A6P5DK44
uniprot id: A0A6P5DLE2
uniprot id: A0A6P5DNK8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:DNAH14
gene id: 9915:DNAH14
uniprot id: A0A6P5D261
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:INHBC
gene id: 9915:INHBC
uniprot id: A0A6P5BTH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

9915:PRPS1
gene id: 9915:PRPS1
uniprot id: A0A6P5CD04
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

9915:PPIP5K2
gene id: 9915:PPIP5K2
uniprot id: A0A6P5C5X6
uniprot id: A0A6P5C5Y2
uniprot id: A0A6P5C5Y7
uniprot id: A0A6P5C5Z3
uniprot id: A0A6P5C5Z9
uniprot id: A0A6P5C605
uniprot id: A0A6P5C610
uniprot id: A0A6P5C632
uniprot id: A0A6P5C638
uniprot id: A0A6P5C644
uniprot id: A0A6P5C6G0
uniprot id: A0A6P5C6G3
uniprot id: A0A6P5C6G8
uniprot id: A0A6P5C7B2
uniprot id: A0A6P5C7B7
uniprot id: A0A6P5C7B9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9915:LOC109554292
gene id: 9915:LOC109554292
uniprot id: A0A6P5ATU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FRRS1
gene id: 9915:FRRS1
uniprot id: A0A6P5BNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

9915:SDR42E1
gene id: 9915:SDR42E1
uniprot id: A0A6P5DEX6
names: Similarity
messages: Belongs to the 3-beta-HSD family.

9915:PLA2G4F
gene id: 9915:PLA2G4F
uniprot id: A0A6P5CEK6
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

9915:LOC109576266
gene id: 9915:LOC109576266
uniprot id: A0A6P5DPQ6
uniprot id: A0A6P5DRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm

9915:SLC35A2
gene id: 9915:SLC35A2
uniprot id: A0A6P5AXM2
uniprot id: A0A6P5B3J4
uniprot id: A0A6P5BFE5
uniprot id: A0A6P5BLY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

9915:LOC109556734
gene id: 9915:LOC109556734
uniprot id: A0A6P5B5H4
names: Similarity
messages: Belongs to the S-100 family.

9915:TMEM150A
gene id: 9915:TMEM150A
uniprot id: A0A6P5CK63
uniprot id: A0A6P5CLW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRAM/TMEM150 family.
messages: Cell membrane
messages: Membrane

9915:LOC109568934
gene id: 9915:LOC109568934
uniprot id: A0A6P5CYE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:USP34
gene id: 9915:USP34
uniprot id: A0A6P5CIR9
uniprot id: A0A6P5CK89
uniprot id: A0A6P5CL27
names: Similarity
messages: Belongs to the peptidase C19 family.

9915:LOC109554241
gene id: 9915:LOC109554241
uniprot id: A0A6P5BJL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RNF167
gene id: 9915:RNF167
uniprot id: A0A6P5DHA8
names: Subcellular Location Annotation
messages: Membrane

9915:SCN3B
gene id: 9915:SCN3B
uniprot id: A0A6P5D277
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN3B (TC 8.A.17) family.
messages: Membrane
messages: Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with NFASC may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.

9915:VPS26B
gene id: 9915:VPS26B
uniprot id: A0A6P5D023
names: Similarity
messages: Belongs to the VPS26 family.

9915:ATF1
gene id: 9915:ATF1
uniprot id: A0A6P5BDB5
uniprot id: A0A6P5BN73
names: Subcellular Location Annotation
messages: Nucleus

9915:SELENOS
gene id: 9915:SELENOS
uniprot id: A0A6P5DM06
uniprot id: A0A6P5DQS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Involved in the degradation process of misfolded endoplasmic reticulum (ER) luminal proteins. Participates in the transfer of misfolded proteins from the ER to the cytosol, where they are destroyed by the proteasome in a ubiquitin-dependent manner. Probably acts by serving as a linker between DERL1, which mediates the retrotranslocation of misfolded proteins into the cytosol, and the ATPase complex VCP, which mediates the translocation and ubiquitination.
messages: Membrane

9915:LOC109568990
gene id: 9915:LOC109568990
uniprot id: A0A6P5CV28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GNG11
gene id: 9915:GNG11
uniprot id: A0A6P5BQ56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

9915:CLDND2
gene id: 9915:CLDND2
uniprot id: A0A6P5D7F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

9915:ILKAP
gene id: 9915:ILKAP
uniprot id: A0A6P5B515
names: Similarity
messages: Belongs to the PP2C family.

9915:GGT7
gene id: 9915:GGT7
uniprot id: A0A6P5CP63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

9915:DMRT1
gene id: 9915:DMRT1
uniprot id: A0A6P5C7I0
names: Similarity
messages: Belongs to the DMRT family.

9915:FAM126B
gene id: 9915:FAM126B
uniprot id: A0A6P5CWM6
uniprot id: A0A6P5CXD5
uniprot id: A0A6P5CZ23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9915:GINS3
gene id: 9915:GINS3
uniprot id: A0A6P5DBK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

9915:ADAMTS4
gene id: 9915:ADAMTS4
uniprot id: A0A6P5B5E2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:HMOX2
gene id: 9915:HMOX2
uniprot id: A0A6P5E1S0
names: Similarity
messages: Belongs to the heme oxygenase family.

9915:LOC109555519
gene id: 9915:LOC109555519
uniprot id: A0A6P5BMT2
names: Subcellular Location Annotation
messages: Nucleus

9915:TAAR8
gene id: 9915:TAAR8
uniprot id: A0A6P5CBQ7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109560920
gene id: 9915:LOC109560920
uniprot id: A0A6P5C024
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PRPF4B
gene id: 9915:PRPF4B
uniprot id: A0A6P5DWL4
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.
messages: Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF.

9915:LOC109564584
gene id: 9915:LOC109564584
uniprot id: A0A6P5CDQ1
names: Subcellular Location Annotation
messages: Membrane

9915:PARD6G
gene id: 9915:PARD6G
uniprot id: A0A6P5DVX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

9915:PLCD4
gene id: 9915:PLCD4
uniprot id: A0A6P5D231
uniprot id: A0A6P5D2J0
uniprot id: A0A6P5D383
uniprot id: A0A6P5D5S0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
messages: Nucleus

9915:RGMA
gene id: 9915:RGMA
uniprot id: A0A6P5DQ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

9915:SERPINB5
gene id: 9915:SERPINB5
uniprot id: A0A6P5E094
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109575575
gene id: 9915:LOC109575575
uniprot id: A0A6P5DNC6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

9915:AGO2
gene id: 9915:AGO2
uniprot id: A0A6P5CU94
uniprot id: A0A6P5CVQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

9915:GLB1
gene id: 9915:GLB1
uniprot id: A0A6P5DR29
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9915:LOC109568841
gene id: 9915:LOC109568841
uniprot id: A0A6P5CY63
names: Subcellular Location Annotation
messages: Membrane

9915:HADHB
gene id: 9915:HADHB
uniprot id: A0A6P5CJA2
uniprot id: A0A6P5CKG8
uniprot id: A0A6P5CKX6
uniprot id: A0A6P5CKY1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9915:LOC109572217
gene id: 9915:LOC109572217
uniprot id: A0A6P5D7V1
names: Similarity
messages: Belongs to the peptidase C48 family.

9915:GDF3
gene id: 9915:GDF3
uniprot id: A0A6P5BVC4
names: Similarity
messages: Belongs to the TGF-beta family.

9915:NTSR1
gene id: 9915:NTSR1
uniprot id: A0A6P5CRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:NPEPL1
gene id: 9915:NPEPL1
uniprot id: A0A6P5CS25
names: Similarity
messages: Belongs to the peptidase M17 family.

9915:TACR2
gene id: 9915:TACR2
uniprot id: A0A6P5BIE1
uniprot id: A0A6P5BIR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109569768
gene id: 9915:LOC109569768
uniprot id: A0A6P5CYE8
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109575194
gene id: 9915:LOC109575194
uniprot id: A0A6P5DKI9
names: Subcellular Location Annotation
messages: Nucleus

9915:MPV17
gene id: 9915:MPV17
uniprot id: A0A6P5CLK4
uniprot id: A0A6P5CMG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9915:PSD4
gene id: 9915:PSD4
uniprot id: A0A6P5CJY9
uniprot id: A0A6P5CKS2
names: Subcellular Location Annotation
messages: ruffle membrane

9915:TOP1
gene id: 9915:TOP1
uniprot id: A0A6P5CQL2
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

9915:LOC109559238
gene id: 9915:LOC109559238
uniprot id: A0A6P5BT41
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9915:FAM160B2
gene id: 9915:FAM160B2
uniprot id: A0A6P5C8F1
names: Similarity
messages: Belongs to the FHIP family.

9915:LOC109563137
gene id: 9915:LOC109563137
uniprot id: A0A6P5C8M7
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

9915:RASGRP4
gene id: 9915:RASGRP4
uniprot id: A0A6P5D778
uniprot id: A0A6P5D9G3
names: Similarity
messages: Belongs to the RASGRP family.

9915:SNURF
gene id: 9915:SNURF
uniprot id: A0A6P5D3J9
names: Similarity
messages: Belongs to the SNURF family.

9915:LOC109568985
gene id: 9915:LOC109568985
uniprot id: A0A6P5CV23
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558467
gene id: 9915:LOC109558467
uniprot id: A0A6P5BS01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109553248
gene id: 9915:LOC109553248
uniprot id: A0A6P5AWJ9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554318
gene id: 9915:LOC109554318
uniprot id: A0A6P5B083
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

9915:LOC109562348
gene id: 9915:LOC109562348
uniprot id: A0A6P5C617
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FKBP5
gene id: 9915:FKBP5
uniprot id: A0A6P5DTF3
names: Subcellular Location Annotation
messages: Nucleus

9915:LIX1
gene id: 9915:LIX1
uniprot id: A0A6P5C5Y5
names: Similarity
messages: Belongs to the LIX1 family.

9915:CTSB
gene id: 9915:CTSB
uniprot id: A0A6P5C7E8
uniprot id: A0A6P5C8B5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase C1 family.
messages: Lysosome

9915:HOXC12
gene id: 9915:HOXC12
uniprot id: A0A6P5BBD4
names: Subcellular Location Annotation
messages: Nucleus

9915:ECH1
gene id: 9915:ECH1
uniprot id: A0A6P5D9T9
uniprot id: A0A6P5DD29
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

9915:SEC13
gene id: 9915:SEC13
uniprot id: A0A6P5DQ04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Lysosome membrane
messages: nuclear pore complex

9915:SLC43A3
gene id: 9915:SLC43A3
uniprot id: A0A6P5D0I1
names: Subcellular Location Annotation
messages: Membrane

9915:TAF11
gene id: 9915:TAF11
uniprot id: A0A6P5DW68
names: Similarity
messages: Belongs to the TAF11 family.

9915:XPO6
gene id: 9915:XPO6
uniprot id: A0A6P5DZE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

9915:UBL4A
gene id: 9915:UBL4A
uniprot id: A0A6P5BG17
uniprot id: A0A6P5BMD6
names: Subcellular Location Annotation
messages: cytosol

9915:MRPL3
gene id: 9915:MRPL3
uniprot id: A0A6P5BXL5
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

9915:SNCG
gene id: 9915:SNCG
uniprot id: A0A6P5AS22
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

9915:ZFP36L1
gene id: 9915:ZFP36L1
uniprot id: A0A6P5CG36
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9915:INTS9
gene id: 9915:INTS9
uniprot id: A0A6P5C6Y2
uniprot id: A0A6P5C755
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

9915:LOC109558193
gene id: 9915:LOC109558193
uniprot id: A0A6P5BRQ7
names: Similarity
messages: Belongs to the mTERF family.

9915:LDLRAD2
gene id: 9915:LDLRAD2
uniprot id: A0A6P5DT93
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PTGDR2
gene id: 9915:PTGDR2
uniprot id: A0A6P5BKL4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:TMTC4
gene id: 9915:TMTC4
uniprot id: A0A6P5CP16
uniprot id: A0A6P5CQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9915:TMPRSS9
gene id: 9915:TMPRSS9
uniprot id: A0A6P5C0J9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ORC2
gene id: 9915:ORC2
uniprot id: A0A6P5CX64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

9915:CHRNA10
gene id: 9915:CHRNA10
uniprot id: A0A6P5CW12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:ADRB3
gene id: 9915:ADRB3
uniprot id: A0A6P5AWQ3
uniprot id: A0A6P5B8I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
messages: Cell membrane
messages: Interacts with ARRDC3.
messages: Membrane

9915:LOC109569290
gene id: 9915:LOC109569290
uniprot id: A0A6P5CWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9915:ABLIM1
gene id: 9915:ABLIM1
uniprot id: A0A6P5E431
names: Subcellular Location Annotation
messages: Cytoplasm

9915:MFSD11
gene id: 9915:MFSD11
uniprot id: A0A6P5DDU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

9915:NAGA
gene id: 9915:NAGA
uniprot id: A0A6P5BW32
uniprot id: A0A6P5BWJ7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

9915:MMS19
gene id: 9915:MMS19
uniprot id: A0A6P5E0D9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MET18/MMS19 family.
messages: Component of the CIA complex.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus
messages: spindle

9915:LOC109565966
gene id: 9915:LOC109565966
uniprot id: A0A6P5CIQ9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:LOC109560364
gene id: 9915:LOC109560364
uniprot id: A0A6P5BXM6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

9915:SGK2
gene id: 9915:SGK2
uniprot id: A0A6P5CSQ5
names: Subcellular Location Annotation
messages: Cytoplasm

9915:IGFBP3
gene id: 9915:IGFBP3
uniprot id: A0A6P5BLA1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:SLC7A9
gene id: 9915:SLC7A9
uniprot id: A0A6P5DC17
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109558422
gene id: 9915:LOC109558422
uniprot id: A0A6P5BLX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ADK
gene id: 9915:ADK
uniprot id: A0A6P5AY49
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Monomer.
messages: Nucleus

9915:SLC16A1
gene id: 9915:SLC16A1
uniprot id: A0A6P5BNC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

9915:ITM2B
gene id: 9915:ITM2B
uniprot id: A0A6P5CPQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

9915:PIK3CG
gene id: 9915:PIK3CG
uniprot id: A0A6P5BQK9
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9915:GATA5
gene id: 9915:GATA5
uniprot id: A0A6P5CNH5
names: Subcellular Location Annotation
messages: Nucleus

9915:DNAH5
gene id: 9915:DNAH5
uniprot id: A0A6P5DLW9
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:LOC109571077
gene id: 9915:LOC109571077
uniprot id: A0A6P5D3F4
uniprot id: A0A6P5D5T9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9915:CD109
gene id: 9915:CD109
uniprot id: A0A6P5CAD3
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

9915:ISOC1
gene id: 9915:ISOC1
uniprot id: A0A6P5C3P3
names: Similarity
messages: Belongs to the isochorismatase family.

9915:MARVELD1
gene id: 9915:MARVELD1
uniprot id: A0A6P5AW14
names: Subcellular Location Annotation
messages: Membrane

9915:IZUMO4
gene id: 9915:IZUMO4
uniprot id: A0A6P5C3M2
names: Similarity
messages: Belongs to the Izumo family.

9915:CTBP2
gene id: 9915:CTBP2
uniprot id: A0A6P5E0Q1
uniprot id: A0A6P5E0Q4
uniprot id: A0A6P5E1G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

9915:BCAS2
gene id: 9915:BCAS2
uniprot id: A0A6P5BGX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

9915:ASPHD2
gene id: 9915:ASPHD2
uniprot id: A0A6P5D621
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

9915:VPS13B
gene id: 9915:VPS13B
uniprot id: A0A6P5CV06
names: Similarity
messages: Belongs to the VPS13 family.

9915:PPP1R14A
gene id: 9915:PPP1R14A
uniprot id: A0A6P5DDM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.

9915:ADGRF5
gene id: 9915:ADGRF5
uniprot id: A0A6P5DSA8
uniprot id: A0A6P5DSB2
uniprot id: A0A6P5DSN4
uniprot id: A0A6P5DW70
uniprot id: A0A6P5DWJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

9915:LOC109569237
gene id: 9915:LOC109569237
uniprot id: A0A6P5CWS0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SERPINB7
gene id: 9915:SERPINB7
uniprot id: A0A6P5DUT4
names: Similarity
messages: Belongs to the serpin family.

9915:PLCG1
gene id: 9915:PLCG1
uniprot id: A0A6P5CQE4
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

9915:ERC1
gene id: 9915:ERC1
uniprot id: A0A6P5BVL5
uniprot id: A0A6P5BVM9
uniprot id: A0A6P5BVN1
uniprot id: A0A6P5BVX0
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109569516
gene id: 9915:LOC109569516
uniprot id: A0A6P5CWW7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ARMCX1
gene id: 9915:ARMCX1
uniprot id: A0A6P5AZ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

9915:LOC109562488
gene id: 9915:LOC109562488
uniprot id: A0A6P5C6M6
names: Similarity
messages: Belongs to the CD200R family.

9915:GLO1
gene id: 9915:GLO1
uniprot id: A0A6P5DX09
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

9915:MYO7A
gene id: 9915:MYO7A
uniprot id: A0A6P5CWB2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9915:BABAM1
gene id: 9915:BABAM1
uniprot id: A0A6P5C1H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BABAM1 family.
messages: Nucleus

9915:C17H22orf39
gene id: 9915:C17H22orf39
uniprot id: A0A6P5D4P4
uniprot id: A0A6P5D5V2
names: Similarity
messages: Belongs to the UPF0545 family.

9915:TMA16
gene id: 9915:TMA16
uniprot id: A0A6P5BWR6
names: Function
names: Similarity
names: Subunit
messages: Associates with pre-60S ribosomal particles.
messages: Belongs to the TMA16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit in the nucleus.

9915:RNASE13
gene id: 9915:RNASE13
uniprot id: A0A6P5CG57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:SOD2
gene id: 9915:SOD2
uniprot id: A0A6P5CDP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Homotetramer.
messages: Mitochondrion matrix

9915:CHGB
gene id: 9915:CHGB
uniprot id: A0A6P5CUS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9915:FAM65A
gene id: 9915:FAM65A
uniprot id: A0A6P5D7Y4
uniprot id: A0A6P5D817
uniprot id: A0A6P5D9L1
uniprot id: A0A6P5DAF0
uniprot id: A0A6P5DBJ4
names: Similarity
messages: Belongs to the RIPOR family.

9915:YES1
gene id: 9915:YES1
uniprot id: A0A6P5DVP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9915:ARHGAP26
gene id: 9915:ARHGAP26
uniprot id: A0A6P5C5H2
uniprot id: A0A6P5C6G5
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

9915:LOC109557063
gene id: 9915:LOC109557063
uniprot id: A0A6P5BQ84
names: Function
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and of the central stalk which is part of the complex rotary element. Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

9915:C20H5orf22
gene id: 9915:C20H5orf22
uniprot id: A0A6P5DJ65
names: Similarity
messages: Belongs to the UPF0489 family.

9915:PODXL2
gene id: 9915:PODXL2
uniprot id: A0A6P5DPB1
names: Subcellular Location Annotation
messages: Membrane

9915:GPR161
gene id: 9915:GPR161
uniprot id: A0A6P5DYE8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:DVL2
gene id: 9915:DVL2
uniprot id: A0A6P5DIR1
names: Similarity
messages: Belongs to the DSH family.

9915:PTGES3L
gene id: 9915:PTGES3L
uniprot id: A0A6P5DGB4
uniprot id: A0A6P5DGB5
uniprot id: A0A6P5DGC0
uniprot id: A0A6P5DHU9
names: Similarity
messages: Belongs to the p23/wos2 family.

9915:TRIT1
gene id: 9915:TRIT1
uniprot id: A0A6P5BIK8
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

9915:STARD3
gene id: 9915:STARD3
uniprot id: A0A6P5DKH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9915:GJD3
gene id: 9915:GJD3
uniprot id: A0A6P5DJ05
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

9915:LOC109564498
gene id: 9915:LOC109564498
uniprot id: A0A6P5CDH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RNF31
gene id: 9915:RNF31
uniprot id: A0A6P5CDD5
uniprot id: A0A6P5CDR9
names: Similarity
messages: Belongs to the RBR family.

9915:GIPC3
gene id: 9915:GIPC3
uniprot id: A0A6P5C3F2
names: Similarity
messages: Belongs to the GIPC family.

9915:CRHBP
gene id: 9915:CRHBP
uniprot id: A0A6P5CDR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

9915:TMEM39B
gene id: 9915:TMEM39B
uniprot id: A0A6P5D956
uniprot id: A0A6P5D966
uniprot id: A0A6P5DB54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

9915:ACD
gene id: 9915:ACD
uniprot id: A0A6P5DA44
uniprot id: A0A6P5DBX7
uniprot id: A0A6P5DBY1
uniprot id: A0A6P5DCA1
uniprot id: A0A6P5DDE1
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

9915:NPFFR1
gene id: 9915:NPFFR1
uniprot id: A0A6P5BI35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

9915:RANBP10
gene id: 9915:RANBP10
uniprot id: A0A6P5DAU1
names: Similarity
messages: Belongs to the RANBP9/10 family.

9915:LOC109555614
gene id: 9915:LOC109555614
uniprot id: A0A6P5AZW4
names: Subcellular Location Annotation
messages: Nucleus

9915:SLC9A3
gene id: 9915:SLC9A3
uniprot id: A0A6P5DND0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

9915:EVX1
gene id: 9915:EVX1
uniprot id: A0A6P5B9W6
names: Subcellular Location Annotation
messages: Nucleus

9915:PPIH
gene id: 9915:PPIH
uniprot id: A0A6P5B419
uniprot id: A0A6P5BPI5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9915:TEC
gene id: 9915:TEC
uniprot id: A0A6P5BY64
uniprot id: A0A6P5BYM5
uniprot id: A0A6P5BZ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane

9915:LOC109569061
gene id: 9915:LOC109569061
uniprot id: A0A6P5CW37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ZMPSTE24
gene id: 9915:ZMPSTE24
uniprot id: A0A6P5B473
uniprot id: A0A6P5BIK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

9915:ZDHHC20
gene id: 9915:ZDHHC20
uniprot id: A0A6P5CLS4
uniprot id: A0A6P5CNL0
uniprot id: A0A6P5CQC4
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:AIF1
gene id: 9915:AIF1
uniprot id: A0A6P5DVE4
names: Subcellular Location Annotation
messages: ruffle membrane

9915:ZDHHC12
gene id: 9915:ZDHHC12
uniprot id: A0A6P5CIE7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:APOA2
gene id: 9915:APOA2
uniprot id: A0A6P5E192
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the apolipoprotein A2 family.
messages: Secreted

9915:FAM175A
gene id: 9915:FAM175A
uniprot id: A0A6P5BZ48
uniprot id: A0A6P5BZZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus

9915:CDA
gene id: 9915:CDA
uniprot id: A0A6P5DJD3
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

9915:LOC109564272
gene id: 9915:LOC109564272
uniprot id: A0A6P5CC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:NRG4
gene id: 9915:NRG4
uniprot id: A0A6P5DL79
uniprot id: A0A6P5DPY8
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109555084
gene id: 9915:LOC109555084
uniprot id: A0A6P5BLG2
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

9915:CPEB2
gene id: 9915:CPEB2
uniprot id: A0A6P5BWU8
names: Similarity
messages: Belongs to the RRM CPEB family.

9915:CRELD1
gene id: 9915:CRELD1
uniprot id: A0A6P5DQ42
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MBOAT1
gene id: 9915:MBOAT1
uniprot id: A0A6P5DU58
names: Subcellular Location Annotation
messages: Membrane

9915:ANO2
gene id: 9915:ANO2
uniprot id: A0A6P5BMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

9915:LOC109576888
gene id: 9915:LOC109576888
uniprot id: A0A6P5DVK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:ARPC1A
gene id: 9915:ARPC1A
uniprot id: A0A6P5E0J6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

9915:MTCL1
gene id: 9915:MTCL1
uniprot id: A0A6P5DVT8
names: Similarity
messages: Belongs to the SOGA family.

9915:ACER1
gene id: 9915:ACER1
uniprot id: A0A6P5C0P2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Membrane

9915:ZIC2
gene id: 9915:ZIC2
uniprot id: A0A6P5CQ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

9915:ABLIM3
gene id: 9915:ABLIM3
uniprot id: A0A6P5C562
uniprot id: A0A6P5C584
uniprot id: A0A6P5C5B5
uniprot id: A0A6P5C5L6
uniprot id: A0A6P5C5M2
uniprot id: A0A6P5C6K8
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109563832
gene id: 9915:LOC109563832
uniprot id: A0A6P5CBA8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KRTAP type 3 family.
messages: Belongs to the PMG family.
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:ERF
gene id: 9915:ERF
uniprot id: A0A6P5D8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:LOC109575242
gene id: 9915:LOC109575242
uniprot id: A0A6P5DL45
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:IQSEC1
gene id: 9915:IQSEC1
uniprot id: A0A6P5DP59
uniprot id: A0A6P5DQR5
names: Similarity
messages: Belongs to the BRAG family.

9915:ZP4
gene id: 9915:ZP4
uniprot id: A0A6P5AXZ0
uniprot id: A0A6P5B9U0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

9915:LOC109558102
gene id: 9915:LOC109558102
uniprot id: A0A6P5BLH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

9915:KCNV1
gene id: 9915:KCNV1
uniprot id: A0A6P5CV46
names: Subcellular Location Annotation
messages: Membrane

9915:RDH12
gene id: 9915:RDH12
uniprot id: A0A6P5CDP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:MSTN
gene id: 9915:MSTN
uniprot id: Q5RZV4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FSTL3.
messages: Secreted
messages: Synthesized as large precursor molecule that undergoes proteolytic cleavage to generate an N-terminal propeptide and a disulfide linked C-terminal dimer, which is the biologically active molecule. The circulating form consists of a latent complex of the C-terminal dimer and other proteins, including its propeptide, which maintain the C-terminal dimer in a latent, inactive state. Ligand activation requires additional cleavage of the prodomain by a tolloid-like metalloproteinase.

9915:CDC14A
gene id: 9915:CDC14A
uniprot id: A0A6P5BJA4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

9915:LOC109560162
gene id: 9915:LOC109560162
uniprot id: A0A6P5BWN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

9915:SFXN3
gene id: 9915:SFXN3
uniprot id: A0A6P5APF7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

9915:SAXO2
gene id: 9915:SAXO2
uniprot id: A0A6P5DM85
uniprot id: A0A6P5DQC5
names: Similarity
messages: Belongs to the FAM154 family.

9915:MED15
gene id: 9915:MED15
uniprot id: A0A6P5D4M8
uniprot id: A0A6P5D702
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 15 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:LHX1
gene id: 9915:LHX1
uniprot id: A0A6P5DHG2
names: Subcellular Location Annotation
messages: Nucleus

9915:MRPL4
gene id: 9915:MRPL4
uniprot id: A0A6P5C279
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

9915:LOC109554896
gene id: 9915:LOC109554896
uniprot id: A0A6P5BL28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

9915:KEG07 p05
gene id: 9915:KEG07_p05
uniprot id: E7BTI7
uniprot id: Q6EMS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

9915:CXCR5
gene id: 9915:CXCR5
uniprot id: A0A6P5CXC6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:SLC25A25
gene id: 9915:SLC25A25
uniprot id: A0A6P5CK45
uniprot id: A0A6P5CLE9
uniprot id: A0A6P5CLU4
uniprot id: A0A6P5CMJ4
uniprot id: A0A6P5CNJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

9915:NID1
gene id: 9915:NID1
uniprot id: A0A6P5AY44
uniprot id: A0A6P5BI09
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: basement membrane

9915:SLC39A8
gene id: 9915:SLC39A8
uniprot id: A0A6P5BXC4
uniprot id: A0A6P5BY21
names: Subcellular Location Annotation
messages: Membrane

9915:PON1
gene id: 9915:PON1
uniprot id: A0A6P5BAB7
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

9915:LMX1B
gene id: 9915:LMX1B
uniprot id: A0A6P5CGP2
names: Subcellular Location Annotation
messages: Nucleus

9915:PNPO
gene id: 9915:PNPO
uniprot id: A0A6P5DIG7
names: Function
names: Similarity
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

9915:LOC109570141
gene id: 9915:LOC109570141
uniprot id: A0A6P5CZP2
names: Subcellular Location Annotation
messages: Nucleus

9915:CACNG3
gene id: 9915:CACNG3
uniprot id: A0A6P5DWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

9915:CREB3L4
gene id: 9915:CREB3L4
uniprot id: A0A6P5AUT4
uniprot id: A0A6P5BCV0
uniprot id: A0A6P5BCW0
uniprot id: A0A6P5BD36
uniprot id: A0A6P5BK24
uniprot id: A0A6P5BK38
uniprot id: A0A6P5BK81
uniprot id: A0A6P5BK96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:MAP6D1
gene id: 9915:MAP6D1
uniprot id: A0A6P5BC43
uniprot id: A0A6P5BQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

9915:SLC30A3
gene id: 9915:SLC30A3
uniprot id: A0A6P5CMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

9915:DNPEP
gene id: 9915:DNPEP
uniprot id: A0A6P5D642
names: Similarity
names: Subunit
messages: Belongs to the peptidase M18 family.
messages: Tetrahedron-shaped homododecamer built from six homodimers.

9915:LOC109569684
gene id: 9915:LOC109569684
uniprot id: A0A6P5CYZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SPOPL
gene id: 9915:SPOPL
uniprot id: A0A6P5CTA3
uniprot id: A0A6P5CUN7
uniprot id: A0A6P5CUP2
names: Similarity
messages: Belongs to the Tdpoz family.

9915:LOC109556971
gene id: 9915:LOC109556971
uniprot id: A0A6P5BJH4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Secreted

9915:CILP
gene id: 9915:CILP
uniprot id: A0A6P5CCC3
names: Subcellular Location Annotation
messages: extracellular matrix

9915:SPATS2L
gene id: 9915:SPATS2L
uniprot id: A0A6P5CWT9
uniprot id: A0A6P5CWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

9915:RHBDF1
gene id: 9915:RHBDF1
uniprot id: A0A6P5DYP5
uniprot id: A0A6P5DZH8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

9915:DCAF10
gene id: 9915:DCAF10
uniprot id: A0A6P5C9F7
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

9915:SCN8A
gene id: 9915:SCN8A
uniprot id: A0A6P5BSP1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

9915:B4GALT5
gene id: 9915:B4GALT5
uniprot id: A0A6P5CTZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9915:GTF2A2
gene id: 9915:GTF2A2
uniprot id: A0A6P5CHB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation.

9915:LOC109570814
gene id: 9915:LOC109570814
uniprot id: A0A6P5D2R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Secreted

9915:CAMSAP1
gene id: 9915:CAMSAP1
uniprot id: A0A6P5CN23
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

9915:SETD6
gene id: 9915:SETD6
uniprot id: A0A6P5D9P4
uniprot id: A0A6P5DAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: Protein-lysine N-methyltransferase.

9915:GRAMD1A
gene id: 9915:GRAMD1A
uniprot id: A0A6P5D8J8
uniprot id: A0A6P5DC08
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:RIBC2
gene id: 9915:RIBC2
uniprot id: A0A6P5BW77
names: Similarity
messages: Belongs to the RIB43A family.

9915:G6PC
gene id: 9915:G6PC
uniprot id: A0A6P5DI27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

9915:KCNMB4
gene id: 9915:KCNMB4
uniprot id: A0A6P5BG79
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9915:SEPT9
gene id: 9915:SEPT9
uniprot id: A0A6P5DFR0
uniprot id: A0A6P5DFR7
uniprot id: A0A6P5DHC5
uniprot id: A0A6P5DI47
uniprot id: A0A6P5DIP0
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

9915:LYRM4
gene id: 9915:LYRM4
uniprot id: A0A6P5DUX1
names: Similarity
messages: Belongs to the complex I LYR family.

9915:NOC3L
gene id: 9915:NOC3L
uniprot id: A0A6P5BGP4
uniprot id: A0A6P5BH57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: nucleolus

9915:SEMA3B
gene id: 9915:SEMA3B
uniprot id: A0A6P5DPV5
uniprot id: A0A6P5DQG1
uniprot id: A0A6P5DTX2
uniprot id: A0A6P5DTX7
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109553375
gene id: 9915:LOC109553375
uniprot id: A0A6P5B8R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:LOC109568079
gene id: 9915:LOC109568079
uniprot id: A0A6P5CS74
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:ECSIT
gene id: 9915:ECSIT
uniprot id: A0A6P5C2N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the ECSIT family.
messages: Cytoplasm
messages: Mitochondrion
messages: Nucleus

9915:LOC109561690
gene id: 9915:LOC109561690
uniprot id: A0A6P5C327
names: Similarity
messages: Belongs to the histone H2B family.

9915:OTOP3
gene id: 9915:OTOP3
uniprot id: A0A6P5DG07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

9915:SLC10A1
gene id: 9915:SLC10A1
uniprot id: A0A6P5CGU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9915:ATF2
gene id: 9915:ATF2
uniprot id: A0A6P5CJ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

9915:AKR1B10
gene id: 9915:AKR1B10
uniprot id: A0A6P5B8F2
uniprot id: A0A6P5BR25
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:DPPA4
gene id: 9915:DPPA4
uniprot id: A0A6P5CBJ9
names: Subcellular Location Annotation
messages: Nucleus

9915:ALDOA
gene id: 9915:ALDOA
uniprot id: A0A6P5DY27
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

9915:NIPAL2
gene id: 9915:NIPAL2
uniprot id: A0A6P5CTK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

9915:GRIN3A
gene id: 9915:GRIN3A
uniprot id: A0A6P5CAR0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:SIRT4
gene id: 9915:SIRT4
uniprot id: A0A6P5D5I2
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: According to some authors, ADP-ribosyltransferase activity of sirtuins may be an inefficient side reaction of the deacetylase activity and may not be physiologically relevant.
messages: Acts as NAD-dependent protein lipoamidase, biotinylase, deacetylase and ADP-ribosyl transferase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitochondrial glutamine metabolism by mediating mono ADP-ribosylation of GLUD1: expressed in response to DNA damage and negatively regulates anaplerosis by inhibiting GLUD1, leading to block metabolism of glutamine into tricarboxylic acid cycle and promoting cell cycle arrest. In response to mTORC1 signal, SIRT4 expression is repressed, promoting anaplerosis and cell proliferation. Acts as a tumor suppressor. Also acts as a NAD-dependent protein deacetylase: mediates deacetylation of 'Lys-471' of MLYCD, inhibiting its activity, thereby acting as a regulator of lipid homeostasis. Does not seem to deacetylate PC. Controls fatty acid oxidation by inhibiting PPARA transcriptional activation. Impairs SIRT1-PPARA interaction probably through the regulation of NAD(+) levels. Down-regulates insulin secretion.
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Interacts with GLUD1, IDE and SLC25A5. Interacts with DLAT and PDHX.
messages: Mitochondrion matrix

9915:LOC109556696
gene id: 9915:LOC109556696
uniprot id: A0A6P5BPY7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GSDMD
gene id: 9915:GSDMD
uniprot id: A0A6P5CUB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9915:LOC109558063
gene id: 9915:LOC109558063
uniprot id: A0A6P5BRM9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9915:ITIH1
gene id: 9915:ITIH1
uniprot id: A0A6P5DQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

9915:BCL9
gene id: 9915:BCL9
uniprot id: A0A6P5B0M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

9915:LOC109559708
gene id: 9915:LOC109559708
uniprot id: A0A6P5BVB7
uniprot id: A0A6P5BVB9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:HOXA4
gene id: 9915:HOXA4
uniprot id: A0A6P5BQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:GSTZ1
gene id: 9915:GSTZ1
uniprot id: A0A6P5CG26
uniprot id: A0A6P5CGQ6
uniprot id: A0A6P5CHR7
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

9915:VGLL1
gene id: 9915:VGLL1
uniprot id: A0A6P5AWK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

9915:KCNN2
gene id: 9915:KCNN2
uniprot id: A0A6P5CD18
names: Subcellular Location Annotation
messages: Membrane

9915:AMHR2
gene id: 9915:AMHR2
uniprot id: A0A6P5BRV8
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

9915:ORC1
gene id: 9915:ORC1
uniprot id: A0A6P5BP76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase. Interacts with CDC6 and KAT7/HBO1. Interacts with LRWD1 predominantly during the G1 phase and with less affinity during mitosis, when phosphorylated.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus

9915:DDX47
gene id: 9915:DDX47
uniprot id: A0A6P5BV31
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

9915:VSNL1
gene id: 9915:VSNL1
uniprot id: A0A6P5CKP8
names: Function
messages: Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

9915:DYDC2
gene id: 9915:DYDC2
uniprot id: A0A6P5BJ29
names: Similarity
messages: Belongs to the dpy-30 family.

9915:ABLIM2
gene id: 9915:ABLIM2
uniprot id: A0A6P5BZT0
uniprot id: A0A6P5BZT4
uniprot id: A0A6P5BZT9
uniprot id: A0A6P5BZU1
uniprot id: A0A6P5BZU5
uniprot id: A0A6P5BZZ2
uniprot id: A0A6P5C000
uniprot id: A0A6P5C005
uniprot id: A0A6P5C049
uniprot id: A0A6P5C054
uniprot id: A0A6P5C061
uniprot id: A0A6P5C0R2
uniprot id: A0A6P5C0S4
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109577731
gene id: 9915:LOC109577731
uniprot id: A0A6P5DUL7
uniprot id: A0A6P5DVU0
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109560546
gene id: 9915:LOC109560546
uniprot id: A0A6P5BZ34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-casein family.
messages: Important role in the capacity of milk to transport calcium phosphate.
messages: Secreted

9915:SLC7A4
gene id: 9915:SLC7A4
uniprot id: A0A6P5D4H5
uniprot id: A0A6P5D5T8
uniprot id: A0A6P5D8D0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109557001
gene id: 9915:LOC109557001
uniprot id: A0A6P5BJI9
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

9915:LOC109556123
gene id: 9915:LOC109556123
uniprot id: A0A6P5B2B4
names: Function
names: Similarity
messages: Belongs to the DDAH family.
messages: Hydrolyzes N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which act as inhibitors of NOS. Has therefore a role in the regulation of nitric oxide generation.

9915:FBN3
gene id: 9915:FBN3
uniprot id: A0A6P5C3V4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:NLRP1
gene id: 9915:NLRP1
uniprot id: A0A6P5DIK7
uniprot id: A0A6P5DLS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NLRP family.
messages: cytosol

9915:PEX1
gene id: 9915:PEX1
uniprot id: A0A6P5BA66
uniprot id: A0A6P5BLM0
uniprot id: A0A6P5BRR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

9915:TNNT1
gene id: 9915:TNNT1
uniprot id: A0A6P5DBS9
uniprot id: A0A6P5DC58
names: Function
names: Similarity
messages: Belongs to the troponin T family.
messages: Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

9915:PIK3IP1
gene id: 9915:PIK3IP1
uniprot id: A0A6P5D7S0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ITGA8
gene id: 9915:ITGA8
uniprot id: A0A6P5CSW9
uniprot id: A0A6P5CV14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:HSPA4L
gene id: 9915:HSPA4L
uniprot id: A0A6P5D386
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9915:RPL35A
gene id: 9915:RPL35A
uniprot id: A0A6P5BNP8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

9915:SDC3
gene id: 9915:SDC3
uniprot id: A0A6P5DCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

9915:AFG3L2
gene id: 9915:AFG3L2
uniprot id: A0A6P5DVI5
uniprot id: A0A6P5DVL9
uniprot id: A0A6P5DZP7
names: Similarity
messages: Belongs to the AAA ATPase family.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9915:LOC109566125
gene id: 9915:LOC109566125
uniprot id: A0A6P5CLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TTC30/dfy-1/fleer family.
messages: Required for polyglutamylation of axonemal tubulin. Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip.
messages: cilium

9915:LOC109577307
gene id: 9915:LOC109577307
uniprot id: A0A6P5DU12
names: Similarity
messages: Belongs to the MHC class II family.

9915:SPATA20
gene id: 9915:SPATA20
uniprot id: A0A6P5DHP7
uniprot id: A0A6P5DKQ7
names: Function
names: Subcellular Location Annotation
messages: May play a role in fertility regulation.
messages: Secreted

9915:PHTF2
gene id: 9915:PHTF2
uniprot id: A0A6P5B6U5
uniprot id: A0A6P5BB85
uniprot id: A0A6P5BB90
uniprot id: A0A6P5BJW0
uniprot id: A0A6P5BJW3
uniprot id: A0A6P5BQI1
uniprot id: A0A6P5BQI3
uniprot id: A0A6P5BQJ4
names: Subcellular Location Annotation
messages: Membrane

9915:RECQL4
gene id: 9915:RECQL4
uniprot id: A0A6P5CWB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9915:TEAD2
gene id: 9915:TEAD2
uniprot id: A0A6P5DAK1
uniprot id: A0A6P5DCP1
names: Subcellular Location Annotation
messages: Nucleus

9915:NEUROD6
gene id: 9915:NEUROD6
uniprot id: A0A6P5B9W1
uniprot id: A0A6P5BRK8
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

9915:NR1H4
gene id: 9915:NR1H4
uniprot id: A0A6P5BTZ3
uniprot id: A0A6P5BTZ6
uniprot id: A0A6P5BU04
uniprot id: A0A6P5BU15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9915:LOC109569270
gene id: 9915:LOC109569270
uniprot id: A0A6P5CWN3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554829
gene id: 9915:LOC109554829
uniprot id: A0A6P5AW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NXF family.
messages: Cytoplasm

9915:DYRK3
gene id: 9915:DYRK3
uniprot id: A0A6P5D2R8
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

9915:EPHB3
gene id: 9915:EPHB3
uniprot id: A0A6P5BQI8
names: Subcellular Location Annotation
messages: Membrane

9915:ACVR1B
gene id: 9915:ACVR1B
uniprot id: A0A6P5BSP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9915:LOC109555672
gene id: 9915:LOC109555672
uniprot id: A0A6P5BN08
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:TACC1
gene id: 9915:TACC1
uniprot id: A0A6P5B8Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

9915:LOC109576896
gene id: 9915:LOC109576896
uniprot id: A0A6P5DUU7
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:MUSK
gene id: 9915:MUSK
uniprot id: A0A6P5C990
uniprot id: A0A6P5CAW3
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:PPL
gene id: 9915:PPL
uniprot id: A0A6P5DXA7
uniprot id: A0A6P5DXH0
uniprot id: A0A6P5E0Y9
names: Subcellular Location Annotation
messages: cytoskeleton

9915:ARHGAP33
gene id: 9915:ARHGAP33
uniprot id: A0A6P5D905
uniprot id: A0A6P5DCD7
names: Similarity
messages: Belongs to the PX domain-containing GAP family.

9915:LOC109564519
gene id: 9915:LOC109564519
uniprot id: A0A6P5CES0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TNPO2
gene id: 9915:TNPO2
uniprot id: A0A6P5C1Y0
uniprot id: A0A6P5C217
uniprot id: A0A6P5C2D2
names: Subcellular Location Annotation
messages: Cytoplasm

9915:MAPK14
gene id: 9915:MAPK14
uniprot id: A0A6P5DS89
uniprot id: A0A6P5DTN0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

9915:PSMB3
gene id: 9915:PSMB3
uniprot id: A0A6P5DI56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

9915:MAP2
gene id: 9915:MAP2
uniprot id: A0A6P5D1E0
uniprot id: A0A6P5D3Z5
uniprot id: A0A6P5D419
names: Subcellular Location Annotation
messages: cytoskeleton

9915:ATP1A3
gene id: 9915:ATP1A3
uniprot id: A0A6P5D6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Membrane

9915:PRKCG
gene id: 9915:PRKCG
uniprot id: A0A6P5DF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane

9915:ST3GAL4
gene id: 9915:ST3GAL4
uniprot id: A0A6P5B0Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:LPO
gene id: 9915:LPO
uniprot id: A0A6P5DD77
uniprot id: A0A6P5DGD1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Secreted

9915:OSBPL3
gene id: 9915:OSBPL3
uniprot id: A0A6P5CFH5
uniprot id: A0A6P5CGH2
names: Similarity
messages: Belongs to the OSBP family.

9915:STXBP2
gene id: 9915:STXBP2
uniprot id: A0A6P5C3Q1
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

9915:ARSG
gene id: 9915:ARSG
uniprot id: A0A6P5DCU9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:TINAG
gene id: 9915:TINAG
uniprot id: A0A6P5DUG6
names: Similarity
messages: Belongs to the peptidase C1 family.

9915:KEG07 p13
gene id: 9915:KEG07_p13
uniprot id: A0A343AY64
uniprot id: Q6EMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (By similarity). Essential for the catalytic activity and assembly of complex I (By similarity).
messages: Membrane
messages: Mitochondrion inner membrane

9915:MPV17L2
gene id: 9915:MPV17L2
uniprot id: A0A6P5C052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9915:HARS
gene id: 9915:HARS
uniprot id: A0A6P5C4V8
uniprot id: A0A6P5C4V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

9915:SKI
gene id: 9915:SKI
uniprot id: A0A6P5D3L6
names: Similarity
messages: Belongs to the SKI family.

9915:SF3B6
gene id: 9915:SF3B6
uniprot id: A0A6P5CMP9
names: Subcellular Location Annotation
messages: Nucleus

9915:CSNK1A1
gene id: 9915:CSNK1A1
uniprot id: A0A6P5C577
uniprot id: A0A6P5C598
uniprot id: A0A6P5C5D3
uniprot id: A0A6P5C5N9
uniprot id: A0A6P5C6M2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:NR2F1
gene id: 9915:NR2F1
uniprot id: A0A6P5C5Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:PYCR1
gene id: 9915:PYCR1
uniprot id: A0A6P5DIF1
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

9915:CHD6
gene id: 9915:CHD6
uniprot id: A0A6P5CT29
names: Similarity
messages: Belongs to the SNF2/RAD54 helicase family.

9915:FKBP6
gene id: 9915:FKBP6
uniprot id: A0A6P5E025
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

9915:LOC109574310
gene id: 9915:LOC109574310
uniprot id: A0A6P5DL47
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

9915:TRAP1
gene id: 9915:TRAP1
uniprot id: A0A6P5E1E5
names: Similarity
messages: Belongs to the heat shock protein 90 family.

9915:GPRC5A
gene id: 9915:GPRC5A
uniprot id: A0A6P5BV18
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:TECRL
gene id: 9915:TECRL
uniprot id: A0A6P5BYY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

9915:F2
gene id: 9915:F2
uniprot id: A0A6P5CXY9
uniprot id: A0A6P5CZM7
names: Caution
names: Function
names: Similarity
messages: Belongs to the peptidase S1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.

9915:PLBD1
gene id: 9915:PLBD1
uniprot id: A0A6P5BV14
uniprot id: A0A6P5BV93
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

9915:CHGA
gene id: 9915:CHGA
uniprot id: A0A6P5DR47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Secreted

9915:ADCY6
gene id: 9915:ADCY6
uniprot id: A0A6P5BFX5
uniprot id: A0A6P5BFX7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9915:LOC109569400
gene id: 9915:LOC109569400
uniprot id: A0A6P5CZP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KRT19
gene id: 9915:KRT19
uniprot id: A0A6P5DIN2
names: Similarity
messages: Belongs to the intermediate filament family.

9915:LOC109558767
gene id: 9915:LOC109558767
uniprot id: A0A6P5BS74
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109554124
gene id: 9915:LOC109554124
uniprot id: A0A6P5BBK9
names: Subcellular Location Annotation
messages: Nucleus

9915:ZACN
gene id: 9915:ZACN
uniprot id: A0A6P5DJR5
names: Subcellular Location Annotation
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:LOC109576634
gene id: 9915:LOC109576634
uniprot id: A0A6P5DR36
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109555742
gene id: 9915:LOC109555742
uniprot id: A0A6P5B097
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109567672
gene id: 9915:LOC109567672
uniprot id: A0A6P5CRF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:DOCK5
gene id: 9915:DOCK5
uniprot id: A0A6P5C8N1
names: Similarity
messages: Belongs to the DOCK family.

9915:TCTE3
gene id: 9915:TCTE3
uniprot id: A0A6P5CD72
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:TAF13
gene id: 9915:TAF13
uniprot id: A0A6P5B6L6
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109569354
gene id: 9915:LOC109569354
uniprot id: A0A6P5CW53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NUDT19
gene id: 9915:NUDT19
uniprot id: A0A6P5DDJ0
names: Similarity
messages: Belongs to the Nudix hydrolase family.

9915:LOC109576783
gene id: 9915:LOC109576783
uniprot id: A0A6P5DRG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

9915:STOM
gene id: 9915:STOM
uniprot id: A0A6P5CA31
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9915:LOC109554019
gene id: 9915:LOC109554019
uniprot id: A0A6P5AT06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TAAR1
gene id: 9915:TAAR1
uniprot id: A0A6P5CA84
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:PRSS36
gene id: 9915:PRSS36
uniprot id: A0A6P5DXJ6
names: Function
names: Subcellular Location Annotation
messages: Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1.
messages: extracellular matrix

9915:CHRM1
gene id: 9915:CHRM1
uniprot id: A0A6P5B1Y2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

9915:ITGA10
gene id: 9915:ITGA10
uniprot id: A0A6P5B5V1
uniprot id: A0A6P5BN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:MAPKAP1
gene id: 9915:MAPKAP1
uniprot id: A0A6P5CJY8
uniprot id: A0A6P5CJZ3
uniprot id: A0A6P5CNE7
names: Similarity
messages: Belongs to the SIN1 family.

9915:SPC24
gene id: 9915:SPC24
uniprot id: A0A6P5C2A7
uniprot id: A0A6P5C2M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

9915:NPHS2
gene id: 9915:NPHS2
uniprot id: A0A6P5D0V4
uniprot id: A0A6P5D3Z1
names: Similarity
messages: Belongs to the band 7/mec-2 family.

9915:GSTP1
gene id: 9915:GSTP1
uniprot id: A0A6P5B1L0
uniprot id: A0A6P5BKR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GST superfamily. Pi family.
messages: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
messages: Cytoplasm
messages: Homodimer.
messages: Mitochondrion
messages: Nucleus

9915:AKR1A1
gene id: 9915:AKR1A1
uniprot id: A0A6P5BPB2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

9915:RBBP5
gene id: 9915:RBBP5
uniprot id: A0A6P5D1A7
uniprot id: A0A6P5D3P5
uniprot id: A0A6P5D513
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109575338
gene id: 9915:LOC109575338
uniprot id: A0A6P5DLD1
uniprot id: A0A6P5DM39
names: Similarity
messages: Belongs to the serpin family.

9915:ALDH1L2
gene id: 9915:ALDH1L2
uniprot id: A0A6P5BU82
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.
messages: In the N-terminal section; belongs to the GART family.

9915:LOC109555601
gene id: 9915:LOC109555601
uniprot id: A0A6P5B5E7
names: Similarity
messages: Belongs to the DEAD box helicase family.

9915:MYO18B
gene id: 9915:MYO18B
uniprot id: A0A6P5D3D9
names: Caution
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109562786
gene id: 9915:LOC109562786
uniprot id: A0A6P5C8C6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109558729
gene id: 9915:LOC109558729
uniprot id: A0A6P5BS60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NDUFB8
gene id: 9915:NDUFB8
uniprot id: A0A6P5E0Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:GPC2
gene id: 9915:GPC2
uniprot id: A0A6P5E0S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

9915:NKX2-2
gene id: 9915:NKX2-2
uniprot id: A0A6P5CRU8
names: Subcellular Location Annotation
messages: Nucleus

9915:ARL5A
gene id: 9915:ARL5A
uniprot id: A0A6P5CRC4
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9915:SNX19
gene id: 9915:SNX19
uniprot id: A0A6P5BK01
names: Similarity
messages: Belongs to the sorting nexin family.

9915:LOC109561186
gene id: 9915:LOC109561186
uniprot id: A0A6P5C0M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:INPP1
gene id: 9915:INPP1
uniprot id: A0A6P5CI36
uniprot id: A0A6P5CI40
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

9915:ADGRF2
gene id: 9915:ADGRF2
uniprot id: A0A6P5DU91
names: Subcellular Location Annotation
messages: Membrane

9915:EMC1
gene id: 9915:EMC1
uniprot id: A0A6P5DIZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:RSPO4
gene id: 9915:RSPO4
uniprot id: A0A6P5CRT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

9915:LOC109553709
gene id: 9915:LOC109553709
uniprot id: A0A6P5BIA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex at least composed of TIMM23, TIMM17 (TIMM17A or TIMM17B) and TIMM50.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

9915:LOC109561115
gene id: 9915:LOC109561115
uniprot id: A0A6P5C0G5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:HOXD10
gene id: 9915:HOXD10
uniprot id: A0A6P5CIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:HEXIM1
gene id: 9915:HEXIM1
uniprot id: A0A6P5DFZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

9915:LOC109568715
gene id: 9915:LOC109568715
uniprot id: A0A6P5CXX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm
messages: May play a role in lipid transport protein in Schwann cells. May bind cholesterol.
messages: Monomer.

9915:TAF7L
gene id: 9915:TAF7L
uniprot id: A0A6P5BGF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

9915:SUPT4H1
gene id: 9915:SUPT4H1
uniprot id: A0A6P5DJX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

9915:IL10
gene id: 9915:IL10
uniprot id: A0A6P5D353
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-10 family.
messages: Homodimer. Interacts with IL10RA and IL10RB.
messages: Immune regulatory cytokine.
messages: Secreted

9915:TDRD7
gene id: 9915:TDRD7
uniprot id: A0A6P5C813
uniprot id: A0A6P5C8I2
uniprot id: A0A6P5C9H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TDRD7 family.
messages: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes: probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required during spermatogenesis.
messages: Cytoplasm
messages: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1.

9915:UBA2
gene id: 9915:UBA2
uniprot id: A0A6P5DBW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

9915:RET
gene id: 9915:RET
uniprot id: A0A6P5AYE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

9915:TCEAL1
gene id: 9915:TCEAL1
uniprot id: A0A6P5BM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family. TFA subfamily.
messages: Nucleus

9915:INTS11
gene id: 9915:INTS11
uniprot id: A0A6P5D2Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

9915:GAREM1
gene id: 9915:GAREM1
uniprot id: A0A6P5DVJ3
names: Similarity
messages: Belongs to the GAREM family.

9915:RPS27L
gene id: 9915:RPS27L
uniprot id: A0A6P5B3N9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

9915:SNCA
gene id: 9915:SNCA
uniprot id: A0A6P5BYB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synuclein family.
messages: Membrane
messages: Nucleus
messages: Secreted
messages: Synapse
messages: axon

9915:UBE2D1
gene id: 9915:UBE2D1
uniprot id: A0A6P5AND1
uniprot id: A0A6P5B708
uniprot id: A0A6P5BGL8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:LOC109573610
gene id: 9915:LOC109573610
uniprot id: A0A6P5DDY6
uniprot id: A0A6P5DFM6
uniprot id: A0A6P5DGC8
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9915:HAO2
gene id: 9915:HAO2
uniprot id: A0A6P5B0R3
uniprot id: A0A6P5BGV7
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

9915:TAS1R3
gene id: 9915:TAS1R3
uniprot id: A0A6P5D465
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:HOXA3
gene id: 9915:HOXA3
uniprot id: A0A6P5BK94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:CDC123
gene id: 9915:CDC123
uniprot id: A0A6P5CQX0
uniprot id: A0A6P5CS01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Required for S phase entry of the cell cycle.

9915:RWDD3
gene id: 9915:RWDD3
uniprot id: A0A6P5B6T8
uniprot id: A0A6P5BHB8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:SLC2A6
gene id: 9915:SLC2A6
uniprot id: A0A6P5CMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane

9915:C1R
gene id: 9915:C1R
uniprot id: A0A6P5BSD0
uniprot id: A0A6P5BSF1
names: Caution
names: Function
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CUL9
gene id: 9915:CUL9
uniprot id: A0A6P5DS73
uniprot id: A0A6P5DVW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cullin family.
messages: Cytoplasm

9915:VPS33A
gene id: 9915:VPS33A
uniprot id: A0A6P5D6I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: clathrin-coated vesicle

9915:LOC109576415
gene id: 9915:LOC109576415
uniprot id: A0A6P5DRV6
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

9915:EPOR
gene id: 9915:EPOR
uniprot id: A0A6P5C2Q3
uniprot id: A0A6P5C3K6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Forms homodimers on EPO stimulation.
messages: Membrane
messages: Receptor for erythropoietin.

9915:LOC109571531
gene id: 9915:LOC109571531
uniprot id: A0A6P5D891
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LUM
gene id: 9915:LUM
uniprot id: A0A6P5BF73
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to laminin.
messages: extracellular matrix

9915:ZC3HC1
gene id: 9915:ZC3HC1
uniprot id: A0A6P5BCC9
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109573311
gene id: 9915:LOC109573311
uniprot id: A0A6P5DFW7
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

9915:RHAG
gene id: 9915:RHAG
uniprot id: A0A6P5DRL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

9915:LOC109564513
gene id: 9915:LOC109564513
uniprot id: A0A6P5CER3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109562290
gene id: 9915:LOC109562290
uniprot id: A0A6P5C5P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LBX1
gene id: 9915:LBX1
uniprot id: A0A6P5BGJ4
names: Subcellular Location Annotation
messages: Nucleus

9915:CD4
gene id: 9915:CD4
uniprot id: A0A6P5BSE2
names: Subcellular Location Annotation
messages: Cell membrane

9915:GRID2
gene id: 9915:GRID2
uniprot id: A0A6P5BXG8
uniprot id: A0A6P5BXZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:LOC109554096
gene id: 9915:LOC109554096
uniprot id: A0A6P5AT90
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:GAPDHS
gene id: 9915:GAPDHS
uniprot id: A0A6P5D911
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

9915:ZDHHC5
gene id: 9915:ZDHHC5
uniprot id: A0A6P5CYF6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:PRKCB
gene id: 9915:PRKCB
uniprot id: A0A6P5DYP9
uniprot id: A0A6P5DZI8
uniprot id: A0A6P5E2L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

9915:RAD1
gene id: 9915:RAD1
uniprot id: A0A6P5DMX5
uniprot id: A0A6P5DNE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

9915:MAF1
gene id: 9915:MAF1
uniprot id: A0A6P5CT31
uniprot id: A0A6P5CVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAF1 family.
messages: Element of the TORC1 signaling pathway that acts as a mediator of diverse signals and that represses RNA polymerase III transcription. Inhibits the de novo assembly of TFIIIB onto DNA.
messages: Nucleus

9915:ACLY
gene id: 9915:ACLY
uniprot id: A0A6P5DE41
uniprot id: A0A6P5DGJ2
uniprot id: A0A6P5DH62
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

9915:EDN1
gene id: 9915:EDN1
uniprot id: A0A6P5DUD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

9915:PHACTR2
gene id: 9915:PHACTR2
uniprot id: A0A6P5CBF4
uniprot id: A0A6P5CBT7
uniprot id: A0A6P5CDC3
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9915:ABHD3
gene id: 9915:ABHD3
uniprot id: A0A6P5DY43
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9915:LOC109569376
gene id: 9915:LOC109569376
uniprot id: A0A6P5CZM1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TNR
gene id: 9915:TNR
uniprot id: A0A6P5D336
uniprot id: A0A6P5D6G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: extracellular matrix

9915:CCR4
gene id: 9915:CCR4
uniprot id: A0A6P5DR26
uniprot id: A0A6P5DUI6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:EIF3I
gene id: 9915:EIF3I
uniprot id: A0A6P5DCD4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm
messages: Phosphorylated by TGF-beta type II receptor.

9915:PELO
gene id: 9915:PELO
uniprot id: A0A6P5DKM6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: Interacts with PINK1, ABCE1 and CNOT4.
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

9915:LOC109572440
gene id: 9915:LOC109572440
uniprot id: A0A6P5D904
names: Subcellular Location Annotation
messages: Nucleus

9915:DEFB119
gene id: 9915:DEFB119
uniprot id: A0A6P5CT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-defensin family.
messages: Has antibacterial activity.
messages: Secreted

9915:LOC109569076
gene id: 9915:LOC109569076
uniprot id: A0A6P5CW44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NKIRAS1
gene id: 9915:NKIRAS1
uniprot id: A0A6P5AQC7
uniprot id: A0A6P5BH87
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

9915:LOC109572374
gene id: 9915:LOC109572374
uniprot id: A0A6P5D8V3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:SLC18A2
gene id: 9915:SLC18A2
uniprot id: A0A6P5E160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Vesicular transporter family.
messages: Cytoplasmic vesicle membrane
messages: Membrane

9915:LOC109554225
gene id: 9915:LOC109554225
uniprot id: A0A6P5BJA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:USP1
gene id: 9915:USP1
uniprot id: A0A6P5BP48
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9915:LOC109572871
gene id: 9915:LOC109572871
uniprot id: A0A6P5DDE9
names: Similarity
messages: Belongs to the metallothionein superfamily. Type 1 family.

9915:LOC109556969
gene id: 9915:LOC109556969
uniprot id: A0A6P5BQ95
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DNM1L
gene id: 9915:DNM1L
uniprot id: A0A6P5BUI8
names: Subcellular Location Annotation
messages: Membrane

9915:ACTR3B
gene id: 9915:ACTR3B
uniprot id: A0A6P5B991
uniprot id: A0A6P5BD28
uniprot id: A0A6P5BL53
uniprot id: A0A6P5BL56
uniprot id: A0A6P5BRF8
names: Similarity
messages: Belongs to the actin family.

9915:LOC109558899
gene id: 9915:LOC109558899
uniprot id: A0A6P5BC68
uniprot id: A0A6P5BMM5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TMEM145
gene id: 9915:TMEM145
uniprot id: A0A6P5D926
uniprot id: A0A6P5D957
uniprot id: A0A6P5DBF3
names: Subcellular Location Annotation
messages: Membrane

9915:DLX2
gene id: 9915:DLX2
uniprot id: A0A6P5DU22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

9915:CAMK2B
gene id: 9915:CAMK2B
uniprot id: A0A6P5B7T3
uniprot id: A0A6P5B7T7
uniprot id: A0A6P5B7U2
uniprot id: A0A6P5BC35
uniprot id: A0A6P5BC39
uniprot id: A0A6P5BKD9
uniprot id: A0A6P5BKE2
uniprot id: A0A6P5BKE5
uniprot id: A0A6P5BKE8
uniprot id: A0A6P5BQV8
uniprot id: A0A6P5BQW1
uniprot id: A0A6P5BQW2
uniprot id: A0A6P5BQY2
uniprot id: A0A6P5BQY4
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9915:GDF11
gene id: 9915:GDF11
uniprot id: A0A6P5BTU9
names: Similarity
messages: Belongs to the TGF-beta family.

9915:USP13
gene id: 9915:USP13
uniprot id: A0A6P5BD02
uniprot id: A0A6P5BRA6
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9915:CORO1B
gene id: 9915:CORO1B
uniprot id: A0A6P5BBM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat coronin family.
messages: Regulates leading edge dynamics and cell motility in fibroblasts. May be involved in cytokinesis and signal transduction.
messages: stress fiber

9915:HSPA9
gene id: 9915:HSPA9
uniprot id: A0A6P5C4Q5
names: Similarity
messages: Belongs to the heat shock protein 70 family.

9915:LOC109569126
gene id: 9915:LOC109569126
uniprot id: A0A6P5CVD1
names: Subcellular Location Annotation
messages: Membrane

9915:TBRG1
gene id: 9915:TBRG1
uniprot id: A0A6P5B1C0
names: Subcellular Location Annotation
messages: Nucleus

9915:LZIC
gene id: 9915:LZIC
uniprot id: A0A6P5D0D7
names: Similarity
messages: Belongs to the CTNNBIP1 family.

9915:LOC109563709
gene id: 9915:LOC109563709
uniprot id: A0A6P5CBV3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

9915:MACF1
gene id: 9915:MACF1
uniprot id: A0A6P5B4B0
uniprot id: A0A6P5B4B5
uniprot id: A0A6P5B8Y4
uniprot id: A0A6P5B8Z0
uniprot id: A0A6P5BIL9
uniprot id: A0A6P5BPJ5
uniprot id: A0A6P5BPJ6
uniprot id: A0A6P5BPJ7
uniprot id: A0A6P5BPM2
uniprot id: A0A6P5BPM4
names: Subcellular Location Annotation
messages: cytoskeleton

9915:PTMA
gene id: 9915:PTMA
uniprot id: A0A6P5D737
uniprot id: A0A6P5D7B1
names: Similarity
messages: Belongs to the pro/parathymosin family.

9915:UBA3
gene id: 9915:UBA3
uniprot id: A0A6P5DP52
uniprot id: A0A6P5DPT0
uniprot id: A0A6P5DSW5
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

9915:LOC109569151
gene id: 9915:LOC109569151
uniprot id: A0A6P5CWJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FOXO4
gene id: 9915:FOXO4
uniprot id: A0A6P5BFH1
names: Subcellular Location Annotation
messages: Nucleus

9915:TSPYL5
gene id: 9915:TSPYL5
uniprot id: A0A6P5CVG1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:ELMO2
gene id: 9915:ELMO2
uniprot id: A0A6P5CQU8
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

9915:MUSTN1
gene id: 9915:MUSTN1
uniprot id: A0A6P5DSB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MUSTANG family.
messages: Nucleus

9915:IFT46
gene id: 9915:IFT46
uniprot id: A0A6P5CYS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT46 family.
messages: cilium
messages: cilium basal body

9915:LOC109568928
gene id: 9915:LOC109568928
uniprot id: A0A6P5CXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ITGB2
gene id: 9915:ITGB2
uniprot id: A0A6P5C0T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

9915:LOC109574578
gene id: 9915:LOC109574578
uniprot id: A0A6P5DJ01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:HHAT
gene id: 9915:HHAT
uniprot id: A0A6P5D3S3
uniprot id: A0A6P5D4X3
names: Subcellular Location Annotation
messages: Membrane

9915:LPGAT1
gene id: 9915:LPGAT1
uniprot id: A0A6P5D159
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Endoplasmic reticulum membrane

9915:LLGL1
gene id: 9915:LLGL1
uniprot id: A0A6P5DF83
uniprot id: A0A6P5DGV3
uniprot id: A0A6P5DHN2
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

9915:GPR35
gene id: 9915:GPR35
uniprot id: A0A6P5B532
uniprot id: A0A6P5BJ04
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109573075
gene id: 9915:LOC109573075
uniprot id: A0A6P5DFF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

9915:LOC109575749
gene id: 9915:LOC109575749
uniprot id: A0A6P5DR32
names: Similarity
messages: Belongs to the serpin family.

9915:SFXN5
gene id: 9915:SFXN5
uniprot id: A0A6P5CHM5
uniprot id: A0A6P5CIL8
uniprot id: A0A6P5CJU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

9915:RPS18
gene id: 9915:RPS18
uniprot id: A0A6P5DSD9
uniprot id: A0A6P5DUP4
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.

9915:VTI1A
gene id: 9915:VTI1A
uniprot id: A0A6P5ANH2
uniprot id: A0A6P5AVD8
uniprot id: A0A6P5B773
uniprot id: A0A6P5BG67
uniprot id: A0A6P5BGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

9915:TRAM1L1
gene id: 9915:TRAM1L1
uniprot id: A0A6P5BX17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAM family.
messages: Membrane

9915:ADGRG5
gene id: 9915:ADGRG5
uniprot id: A0A6P5DBW9
uniprot id: A0A6P5DC22
uniprot id: A0A6P5DF76
names: Subcellular Location Annotation
messages: Membrane

9915:P2RX2
gene id: 9915:P2RX2
uniprot id: A0A6P5D538
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

9915:TPX2
gene id: 9915:TPX2
uniprot id: A0A6P5CNX4
uniprot id: A0A6P5CQJ8
uniprot id: A0A6P5CRC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

9915:SLC25A27
gene id: 9915:SLC25A27
uniprot id: A0A6P5DXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:POU2F1
gene id: 9915:POU2F1
uniprot id: A0A6P5DUI7
uniprot id: A0A6P5DY64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-2 subfamily.
messages: Nucleus
messages: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.

9915:LOC109570094
gene id: 9915:LOC109570094
uniprot id: A0A6P5D239
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

9915:KIFC3
gene id: 9915:KIFC3
uniprot id: A0A6P5DDQ1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:PPP1CB
gene id: 9915:PPP1CB
uniprot id: A0A6P5CLF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cytoplasm
messages: nucleolus
messages: nucleoplasm

9915:NCK1
gene id: 9915:NCK1
uniprot id: A0A6P5BWG1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

9915:TOM1L1
gene id: 9915:TOM1L1
uniprot id: A0A6P5DF08
uniprot id: A0A6P5DHE5
names: Similarity
messages: Belongs to the TOM1 family.

9915:RASSF5
gene id: 9915:RASSF5
uniprot id: A0A6P5D388
names: Subcellular Location Annotation
messages: cytoskeleton

9915:LOC109558156
gene id: 9915:LOC109558156
uniprot id: A0A6P5BRP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:OLFM3
gene id: 9915:OLFM3
uniprot id: A0A6P5B667
uniprot id: A0A6P5BJK4
uniprot id: A0A6P5BQ82
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9915:DGCR14
gene id: 9915:DGCR14
uniprot id: A0A6P5D5P5
uniprot id: A0A6P5D944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

9915:PIAS4
gene id: 9915:PIAS4
uniprot id: A0A6P5C322
names: Similarity
messages: Belongs to the PIAS family.

9915:LOC109558371
gene id: 9915:LOC109558371
uniprot id: A0A6P5BRW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EHD4
gene id: 9915:EHD4
uniprot id: A0A6P5CGS5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

9915:LOC109562511
gene id: 9915:LOC109562511
uniprot id: A0A6P5C695
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ATP12A
gene id: 9915:ATP12A
uniprot id: A0A6P5CPF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Membrane

9915:HNRNPC
gene id: 9915:HNRNPC
uniprot id: A0A6P5CES3
uniprot id: A0A6P5CF80
uniprot id: A0A6P5CF84
uniprot id: A0A6P5CG48
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

9915:MOGAT1
gene id: 9915:MOGAT1
uniprot id: A0A6P5D4Z0
uniprot id: A0A6P5D501
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PPTC7
gene id: 9915:PPTC7
uniprot id: A0A6P5D3X8
names: Similarity
messages: Belongs to the PP2C family.

9915:PIK3CD
gene id: 9915:PIK3CD
uniprot id: A0A6P5D206
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

9915:MFNG
gene id: 9915:MFNG
uniprot id: A0A6P5BUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:HCN2
gene id: 9915:HCN2
uniprot id: A0A6P5C0R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel HCN family.
messages: Cell membrane
messages: Membrane

9915:MGP
gene id: 9915:MGP
uniprot id: A0A6P5BUZ9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
messages: Belongs to the osteocalcin/matrix Gla protein family.
messages: Requires vitamin K-dependent gamma-carboxylation for its function.
messages: Secreted

9915:LOC109576900
gene id: 9915:LOC109576900
uniprot id: A0A6P5DV24
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:KHDRBS1
gene id: 9915:KHDRBS1
uniprot id: A0A6P5D991
names: Similarity
messages: Belongs to the KHDRBS family.

9915:LOC109575533
gene id: 9915:LOC109575533
uniprot id: A0A6P5DQH4
names: Similarity
messages: Belongs to the SEC6 family.

9915:SCMH1
gene id: 9915:SCMH1
uniprot id: A0A6P5B438
uniprot id: A0A6P5B8S3
uniprot id: A0A6P5BII6
uniprot id: A0A6P5BPH0
uniprot id: A0A6P5BPJ2
uniprot id: A0A6P5BPJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

9915:LOC109576911
gene id: 9915:LOC109576911
uniprot id: A0A6P5DV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:KTI12
gene id: 9915:KTI12
uniprot id: A0A6P5B3C4
names: Similarity
messages: Belongs to the KTI12 family.

9915:LOC109569565
gene id: 9915:LOC109569565
uniprot id: A0A6P5CX95
uniprot id: A0A6P5CY50
uniprot id: A0A6P5CZS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

9915:LOC109561030
gene id: 9915:LOC109561030
uniprot id: A0A6P5C0A0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:AK3
gene id: 9915:AK3
uniprot id: A0A6P5C7K5
uniprot id: A0A6P5C7W8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

9915:LOC109566446
gene id: 9915:LOC109566446
uniprot id: A0A6P5CLJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KPNB1
gene id: 9915:KPNB1
uniprot id: A0A6P5DET0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

9915:LOC109569418
gene id: 9915:LOC109569418
uniprot id: A0A6P5CZS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DFNA5
gene id: 9915:DFNA5
uniprot id: A0A6P5CG55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

9915:EIF4EBP3
gene id: 9915:EIF4EBP3
uniprot id: A0A6P5C4V1
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

9915:OTUB1
gene id: 9915:OTUB1
uniprot id: A0A6P5B0A8
names: Similarity
messages: Belongs to the peptidase C65 family.

9915:MAP2K1
gene id: 9915:MAP2K1
uniprot id: A0A6P5CD11
uniprot id: A0A6P5CDE2
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:KIF6
gene id: 9915:KIF6
uniprot id: A0A6P5DTV5
uniprot id: A0A6P5DU82
uniprot id: A0A6P5DV67
uniprot id: A0A6P5DV71
uniprot id: A0A6P5DXN9
uniprot id: A0A6P5DY42
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:GATA1
gene id: 9915:GATA1
uniprot id: A0A6P5BM35
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109569082
gene id: 9915:LOC109569082
uniprot id: A0A6P5CV95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109562517
gene id: 9915:LOC109562517
uniprot id: A0A6P5C6C6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576960
gene id: 9915:LOC109576960
uniprot id: A0A6P5DW54
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TNFSF11
gene id: 9915:TNFSF11
uniprot id: A0A6P5CMS9
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:CNGA1
gene id: 9915:CNGA1
uniprot id: A0A6P5BY59
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA1 subfamily.
messages: Subunit of the rod cyclic GMP-gated cation channel, which is involved in the final stage of the phototransduction pathway. When light hits rod photoreceptors, cGMP concentrations decrease causing rapid closure of CNGA1/CNGB1 channels and, therefore, hyperpolarization of the membrane potential.

9915:DNASE1L2
gene id: 9915:DNASE1L2
uniprot id: A0A6P5DZN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9915:RPL22L1
gene id: 9915:RPL22L1
uniprot id: A0A6P5BLM7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9915:TMEM87A
gene id: 9915:TMEM87A
uniprot id: A0A6P5CEL5
uniprot id: A0A6P5CFR3
names: Subcellular Location Annotation
messages: Membrane

9915:RPS28
gene id: 9915:RPS28
uniprot id: A0A6P5C2K3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS28 family.
messages: Component of the 40S small ribosomal subunit.

9915:CCNL1
gene id: 9915:CCNL1
uniprot id: A0A6P5BMW5
uniprot id: A0A6P5BSL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

9915:B3GNT7
gene id: 9915:B3GNT7
uniprot id: A0A6P5D769
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:SCRN2
gene id: 9915:SCRN2
uniprot id: A0A6P5DHG1
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9915:ADAM9
gene id: 9915:ADAM9
uniprot id: A0A6P5AQL2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:HABP4
gene id: 9915:HABP4
uniprot id: A0A6P5C8U9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:FOXO3
gene id: 9915:FOXO3
uniprot id: A0A6P5CBT1
names: Subcellular Location Annotation
messages: Nucleus

9915:HMOX1
gene id: 9915:HMOX1
uniprot id: A0A6P5BUG8
names: Similarity
messages: Belongs to the heme oxygenase family.

9915:HOXA10
gene id: 9915:HOXA10
uniprot id: A0A6P5BBW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

9915:LOC109575281
gene id: 9915:LOC109575281
uniprot id: A0A6P5DKN3
names: Subcellular Location Annotation
messages: Membrane

9915:MAP6
gene id: 9915:MAP6
uniprot id: A0A6P5D0H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STOP family.
messages: cytoskeleton

9915:UCN3
gene id: 9915:UCN3
uniprot id: A0A6P5CRV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9915:MVB12A
gene id: 9915:MVB12A
uniprot id: A0A6P5C1V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9915:ANKS3
gene id: 9915:ANKS3
uniprot id: A0A6P5DYN0
uniprot id: A0A6P5DZG2
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:ACRBP
gene id: 9915:ACRBP
uniprot id: A0A6P5BRV2
names: Subcellular Location Annotation
messages: acrosome

9915:TNFRSF4
gene id: 9915:TNFRSF4
uniprot id: A0A6P5D265
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:DKK1
gene id: 9915:DKK1
uniprot id: A0A6P5APL1
names: Similarity
messages: Belongs to the dickkopf family.

9915:WBSCR17
gene id: 9915:WBSCR17
uniprot id: A0A6P5E360
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:HIGD1C
gene id: 9915:HIGD1C
uniprot id: A0A6P5BS67
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

9915:LOC109564585
gene id: 9915:LOC109564585
uniprot id: A0A6P5CE46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SMAD4
gene id: 9915:SMAD4
uniprot id: A0A6P5DWD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9915:STRIP2
gene id: 9915:STRIP2
uniprot id: A0A6P5BCC4
uniprot id: A0A6P5BKL9
names: Similarity
messages: Belongs to the STRIP family.

9915:LOC109570872
gene id: 9915:LOC109570872
uniprot id: A0A6P5D3Y6
names: Similarity
messages: Belongs to the Bcl-2 family.

9915:CNDP1
gene id: 9915:CNDP1
uniprot id: A0A6P5DW26
uniprot id: A0A6P5DW67
uniprot id: A0A6P5E0A1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

9915:EIF2AK3
gene id: 9915:EIF2AK3
uniprot id: A0A6P5CK05
uniprot id: A0A6P5CLR9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9915:MYH7B
gene id: 9915:MYH7B
uniprot id: A0A6P5CSS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: myofibril

9915:USP39
gene id: 9915:USP39
uniprot id: A0A6P5CJQ4
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109561771
gene id: 9915:LOC109561771
uniprot id: A0A6P5C367
uniprot id: A0A6P5C3H5
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9915:GBX1
gene id: 9915:GBX1
uniprot id: A0A6P5B967
names: Subcellular Location Annotation
messages: Nucleus

9915:ADRA2B
gene id: 9915:ADRA2B
uniprot id: A0A6P5CJX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.
messages: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA2B sub-subfamily.
messages: Cell membrane
messages: Membrane

9915:LOC109555878
gene id: 9915:LOC109555878
uniprot id: A0A6P5B634
uniprot id: A0A6P5BN94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

9915:MFSD3
gene id: 9915:MFSD3
uniprot id: A0A6P5CUC7
uniprot id: A0A6P5CVI1
uniprot id: A0A6P5CWJ6
names: Subcellular Location Annotation
messages: Membrane

9915:FUT1
gene id: 9915:FUT1
uniprot id: A0A6P5DC04
uniprot id: A0A6P5DDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 11 family.
messages: Golgi stack membrane
messages: Membrane

9915:TSHB
gene id: 9915:TSHB
uniprot id: A0A6P5BNB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

9915:LOC109578763
gene id: 9915:LOC109578763
uniprot id: A0A6P5DZN0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the globin family.
messages: Heterotetramer of two alpha chains and two beta chains.
messages: Involved in oxygen transport from the lung to the various peripheral tissues.

9915:LOC109568920
gene id: 9915:LOC109568920
uniprot id: A0A6P5CYD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPL38
gene id: 9915:RPL38
uniprot id: A0A6P5DIB7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

9915:FAM162B
gene id: 9915:FAM162B
uniprot id: A0A6P5CBF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0389 family.
messages: Membrane

9915:ZKSCAN5
gene id: 9915:ZKSCAN5
uniprot id: A0A6P5DXD9
uniprot id: A0A6P5E004
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109576946
gene id: 9915:LOC109576946
uniprot id: A0A6P5DRX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HSPA13
gene id: 9915:HSPA13
uniprot id: A0A6P5C120
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Binds UBQLN2.
messages: Endoplasmic reticulum
messages: Has peptide-independent ATPase activity.
messages: Microsome

9915:SMC3
gene id: 9915:SMC3
uniprot id: A0A6P5AVS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

9915:LOC109562834
gene id: 9915:LOC109562834
uniprot id: A0A6P5C787
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

9915:MKX
gene id: 9915:MKX
uniprot id: A0A6P5CRR6
uniprot id: A0A6P5CU85
uniprot id: A0A6P5CVB3
names: Subcellular Location Annotation
messages: Nucleus

9915:HMGN1
gene id: 9915:HMGN1
uniprot id: A0A6P5BY49
uniprot id: A0A6P5BZ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGN family.
messages: Nucleus

9915:LOC109577277
gene id: 9915:LOC109577277
uniprot id: A0A6P5DTY0
names: Similarity
messages: Belongs to the serpin family.

9915:ZBED9
gene id: 9915:ZBED9
uniprot id: A0A6P5DV86
names: Subcellular Location Annotation
messages: Nucleus

9915:RAPGEF2
gene id: 9915:RAPGEF2
uniprot id: A0A6P5D7T0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

9915:EMP3
gene id: 9915:EMP3
uniprot id: A0A6P5DBK0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Probably involved in cell proliferation and cell-cell interactions.

9915:PDE4A
gene id: 9915:PDE4A
uniprot id: A0A6P5C264
uniprot id: A0A6P5C2J5
uniprot id: A0A6P5C3D7
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:LOC109569318
gene id: 9915:LOC109569318
uniprot id: A0A6P5CWZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TRMT6
gene id: 9915:TRMT6
uniprot id: A0A6P5CSD6
uniprot id: A0A6P5CTC3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

9915:FAM76B
gene id: 9915:FAM76B
uniprot id: A0A6P5CZ40
uniprot id: A0A6P5D0M2
names: Similarity
messages: Belongs to the FAM76 family.

9915:EBP
gene id: 9915:EBP
uniprot id: A0A6P5AZ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:SENP2
gene id: 9915:SENP2
uniprot id: A0A6P5BQB9
uniprot id: A0A6P5BQD6
uniprot id: A0A6P5BQD8
names: Similarity
messages: Belongs to the peptidase C48 family.

9915:LOC109564520
gene id: 9915:LOC109564520
uniprot id: A0A6P5CDK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PROKR1
gene id: 9915:PROKR1
uniprot id: A0A6P5CIX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

9915:CTNNA1
gene id: 9915:CTNNA1
uniprot id: A0A6P5C520
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

9915:MTHFD1L
gene id: 9915:MTHFD1L
uniprot id: A0A6P5C9U0
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

9915:RHPN1
gene id: 9915:RHPN1
uniprot id: A0A6P5CVJ7
uniprot id: A0A6P5CXS8
names: Similarity
messages: Belongs to the RHPN family.

9915:LOC109569208
gene id: 9915:LOC109569208
uniprot id: A0A6P5CY51
names: Similarity
messages: Belongs to the globin family.

9915:ACO2
gene id: 9915:ACO2
uniprot id: A0A6P5BW43
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

9915:CSNK2B
gene id: 9915:CSNK2B
uniprot id: A0A6P5DWT1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Participates in Wnt signaling.
messages: Tetramer of two alpha and two beta subunits.

9915:IKBKE
gene id: 9915:IKBKE
uniprot id: A0A6P5D2G8
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109561047
gene id: 9915:LOC109561047
uniprot id: A0A6P5C0B1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LHX9
gene id: 9915:LHX9
uniprot id: A0A6P5D001
uniprot id: A0A6P5D3Q1
names: Subcellular Location Annotation
messages: Nucleus

9915:CCNT1
gene id: 9915:CCNT1
uniprot id: A0A6P5BND9
names: Similarity
messages: Belongs to the cyclin family. Cyclin C subfamily.

9915:LOC109568074
gene id: 9915:LOC109568074
uniprot id: A0A6P5CTG0
names: Similarity
messages: Belongs to the aldo/keto reductase family.

9915:POU1F1
gene id: 9915:POU1F1
uniprot id: A0A6P5CBI6
uniprot id: A0A6P5CBJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-1 subfamily.
messages: Nucleus

9915:LOC109565627
gene id: 9915:LOC109565627
uniprot id: A0A6P5CHB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLCO5A1
gene id: 9915:SLCO5A1
uniprot id: A0A6P5CTV2
uniprot id: A0A6P5CUU8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LAMA1
gene id: 9915:LAMA1
uniprot id: A0A6P5DUP2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

9915:ERN1
gene id: 9915:ERN1
uniprot id: A0A6P5DJF0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:NUPR2
gene id: 9915:NUPR2
uniprot id: A0A6P5DWI2
names: Similarity
messages: Belongs to the NUPR family.

9915:LOC109571866
gene id: 9915:LOC109571866
uniprot id: A0A6P5D880
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109576906
gene id: 9915:LOC109576906
uniprot id: A0A6P5DV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:TIRAP
gene id: 9915:TIRAP
uniprot id: A0A6P5B1I0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

9915:PTHLH
gene id: 9915:PTHLH
uniprot id: A0A6P5BUQ8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the parathyroid hormone family.
messages: Cytoplasm
messages: Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Up-regulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity of these cells to BMPs and allows them to respond to BMP4 in a paracrine and/or autocrine fashion. BMP4 signaling in the mesenchyme, in turn, triggers epithelial outgrowth and augments MSX2 expression, which causes the mammary mesenchyme to inhibit hair follicle formation within the nipple sheath.
messages: Nucleus
messages: Osteostatin is a potent inhibitor of osteoclastic bone resorption.
messages: PTHrP interacts with PTH1R (via N-terminal extracellular domain).
messages: Secreted
messages: There are several secretory forms, including osteostatin, arising from endoproteolytic cleavage of the initial translation product. Each of these secretory forms is believed to have one or more of its own receptors that mediates the normal paracrine, autocrine and endocrine actions.

9915:BBOF1
gene id: 9915:BBOF1
uniprot id: A0A6P5CH32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basal body protein required in multiciliate cells to align and maintain cilia orientation in response to flow. May act by mediating a maturation step that stabilizes and aligns cilia orientation. Not required to respond to planar cell polarity (PCP) or flow-based orientation cues.
messages: Belongs to the BBOF1 family.
messages: cilium basal body

9915:UGT2A2
gene id: 9915:UGT2A2
uniprot id: A0A6P5BYM9
uniprot id: A0A6P5BYN2
uniprot id: A0A6P5BZ25
uniprot id: A0A6P5BZI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9915:LOC109559799
gene id: 9915:LOC109559799
uniprot id: A0A6P5BW20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:TM9SF1
gene id: 9915:TM9SF1
uniprot id: A0A6P5CEI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

9915:ALKBH8
gene id: 9915:ALKBH8
uniprot id: A0A6P5CZH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

9915:KCNA2
gene id: 9915:KCNA2
uniprot id: A0A6P5BH44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.2/KCNA2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Presynaptic cell membrane
messages: Synaptic cell membrane
messages: lamellipodium membrane
messages: paranodal septate junction
messages: synaptosome

9915:LOC109560522
gene id: 9915:LOC109560522
uniprot id: A0A6P5BYL1
uniprot id: A0A6P5BZG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9915:TSSK2
gene id: 9915:TSSK2
uniprot id: A0A6P5D7R4
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:XIRP2
gene id: 9915:XIRP2
uniprot id: A0A6P5CNW2
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

9915:CCNYL1
gene id: 9915:CCNYL1
uniprot id: A0A6P5D3H3
uniprot id: A0A6P5D3H8
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

9915:LOC109560534
gene id: 9915:LOC109560534
uniprot id: A0A6P5BYN1
uniprot id: A0A6P5BZH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

9915:SUOX
gene id: 9915:SUOX
uniprot id: A0A6P5BTR6
names: Function
messages: Catalyzes the oxidation of sulfite to sulfate, the terminal reaction in the oxidative degradation of sulfur-containing amino acids.

9915:ERBB3
gene id: 9915:ERBB3
uniprot id: A0A6P5BTQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

9915:GDAP1L1
gene id: 9915:GDAP1L1
uniprot id: A0A6P5CQL3
uniprot id: A0A6P5CRN7
uniprot id: A0A6P5CS21
uniprot id: A0A6P5CU32
names: Similarity
messages: Belongs to the GST superfamily.

9915:BCO1
gene id: 9915:BCO1
uniprot id: A0A6P5D8Z5
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

9915:DHDH
gene id: 9915:DHDH
uniprot id: A0A6P5D7W7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

9915:EXOC3L1
gene id: 9915:EXOC3L1
uniprot id: A0A6P5DDP6
names: Similarity
messages: Belongs to the SEC6 family.

9915:MARVELD2
gene id: 9915:MARVELD2
uniprot id: A0A6P5DKS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9915:FGFR1OP2
gene id: 9915:FGFR1OP2
uniprot id: A0A6P5BUR2
uniprot id: A0A6P5BUR6
names: Similarity
messages: Belongs to the SIKE family.

9915:FAM92A
gene id: 9915:FAM92A
uniprot id: A0A6P5CUR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CIBAR family.
messages: centriole
messages: cilium basal body

9915:LOC109568907
gene id: 9915:LOC109568907
uniprot id: A0A6P5CXE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KCNJ13
gene id: 9915:KCNJ13
uniprot id: A0A6P5B4Q9
uniprot id: A0A6P5BIW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

9915:CFAP126
gene id: 9915:CFAP126
uniprot id: A0A6P5DWL5
uniprot id: A0A6P5DWN2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the Flattop family.

9915:HLF
gene id: 9915:HLF
uniprot id: A0A6P5DFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

9915:NAB1
gene id: 9915:NAB1
uniprot id: A0A6P5CG76
uniprot id: A0A6P5CGW4
uniprot id: A0A6P5CHF7
uniprot id: A0A6P5CHW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

9915:LOC109562107
gene id: 9915:LOC109562107
uniprot id: A0A6P5C4T2
names: Function
names: Subunit
messages: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
messages: Interacts with hair keratins.

9915:PLCB2
gene id: 9915:PLCB2
uniprot id: A0A6P5CGI4
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

9915:EIF3G
gene id: 9915:EIF3G
uniprot id: A0A6P5C2H4
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of FRAP1 and RAPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts (via C-terminus) with AIFM1 (via N-terminus).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. This subunit can bind 18S rRNA.
messages: perinuclear region

9915:SYNGR1
gene id: 9915:SYNGR1
uniprot id: A0A6P5BVW2
uniprot id: A0A6P5BVW9
uniprot id: A0A6P5BW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

9915:RPAP1
gene id: 9915:RPAP1
uniprot id: A0A6P5CFN3
names: Similarity
messages: Belongs to the RPAP1 family.

9915:OLFM2
gene id: 9915:OLFM2
uniprot id: A0A6P5C3A3
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

9915:LOC109576928
gene id: 9915:LOC109576928
uniprot id: A0A6P5DTA5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PXMP2
gene id: 9915:PXMP2
uniprot id: A0A6P5D7P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

9915:ACYP1
gene id: 9915:ACYP1
uniprot id: A0A6P5CFX3
uniprot id: A0A6P5CH55
names: Similarity
messages: Belongs to the acylphosphatase family.

9915:SULT1C2
gene id: 9915:SULT1C2
uniprot id: A0A6P5CJW6
uniprot id: A0A6P5CLM2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:VPS4A
gene id: 9915:VPS4A
uniprot id: A0A6P5D9F5
uniprot id: A0A6P5DAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

9915:UNC5CL
gene id: 9915:UNC5CL
uniprot id: A0A6P5DTT2
uniprot id: A0A6P5DXY6
names: Similarity
messages: Belongs to the unc-5 family.

9915:METTL6
gene id: 9915:METTL6
uniprot id: A0A6P5C2X8
uniprot id: A0A6P5C311
uniprot id: A0A6P5C312
uniprot id: A0A6P5C330
uniprot id: A0A6P5C354
uniprot id: A0A6P5C497
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

9915:ABI2
gene id: 9915:ABI2
uniprot id: A0A6P5CZ80
uniprot id: A0A6P5CZF4
uniprot id: A0A6P5CZH7
uniprot id: A0A6P5CZJ1
uniprot id: A0A6P5D1Y4
uniprot id: A0A6P5D1Z5
uniprot id: A0A6P5D220
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

9915:LOC109565302
gene id: 9915:LOC109565302
uniprot id: A0A6P5CIF9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109568835
gene id: 9915:LOC109568835
uniprot id: A0A6P5CUQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DLK1
gene id: 9915:DLK1
uniprot id: A0A6P5DP62
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TLL2
gene id: 9915:TLL2
uniprot id: A0A6P5B8A3
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109560668
gene id: 9915:LOC109560668
uniprot id: A0A6P5BZN0
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

9915:MMP14
gene id: 9915:MMP14
uniprot id: A0A6P5CF52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Cytoplasm
messages: Melanosome

9915:SLC6A3
gene id: 9915:SLC6A3
uniprot id: A0A6P5DMH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A3 subfamily.
messages: Cell membrane
messages: Membrane
messages: axon
messages: neuron projection

9915:FAM83B
gene id: 9915:FAM83B
uniprot id: A0A6P5DUI9
names: Similarity
messages: Belongs to the FAM83 family.

9915:LOC109573475
gene id: 9915:LOC109573475
uniprot id: A0A6P5DFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:PANX1
gene id: 9915:PANX1
uniprot id: A0A6P5BD41
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

9915:SHROOM1
gene id: 9915:SHROOM1
uniprot id: A0A6P5C4G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

9915:ARSI
gene id: 9915:ARSI
uniprot id: A0A6P5C6P4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:ENTPD4
gene id: 9915:ENTPD4
uniprot id: A0A6P5C8L3
uniprot id: A0A6P5C9U4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

9915:SLC5A2
gene id: 9915:SLC5A2
uniprot id: A0A6P5DYM5
uniprot id: A0A6P5DZF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

9915:TOP2A
gene id: 9915:TOP2A
uniprot id: A0A6P5DL09
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase family.
messages: Homodimer.
messages: Key decatenating enzyme that alters DNA topology by binding to two double-stranded DNA molecules, generating a double-stranded break in one of the strands, passing the intact strand through the broken strand, and religating the broken strand.

9915:NCAPG
gene id: 9915:NCAPG
uniprot id: A0A6P5BXM7
uniprot id: A0A6P5BY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

9915:LOC109566795
gene id: 9915:LOC109566795
uniprot id: A0A6P5CLI3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109572856
gene id: 9915:LOC109572856
uniprot id: A0A6P5DDF4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production.
messages: Membrane
messages: trans-Golgi network

9915:RPGRIP1
gene id: 9915:RPGRIP1
uniprot id: A0A6P5CD06
names: Similarity
messages: Belongs to the RPGRIP1 family.

9915:TRPM8
gene id: 9915:TRPM8
uniprot id: A0A6P5B4T7
uniprot id: A0A6P5BPU2
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555865
gene id: 9915:LOC109555865
uniprot id: A0A6P5B619
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9915:CREB3L3
gene id: 9915:CREB3L3
uniprot id: A0A6P5C317
uniprot id: A0A6P5C3C0
uniprot id: A0A6P5C3D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:PFKFB2
gene id: 9915:PFKFB2
uniprot id: A0A6P5D154
uniprot id: A0A6P5D3I9
uniprot id: A0A6P5D4U9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9915:BRPF3
gene id: 9915:BRPF3
uniprot id: A0A6P5DX57
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109562657
gene id: 9915:LOC109562657
uniprot id: A0A6P5C6M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:C11H2orf40
gene id: 9915:C11H2orf40
uniprot id: A0A6P5CJX8
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

9915:CDC25C
gene id: 9915:CDC25C
uniprot id: A0A6P5C513
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

9915:TUBB6
gene id: 9915:TUBB6
uniprot id: A0A6P5DZG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: cytoskeleton

9915:ST6GALNAC3
gene id: 9915:ST6GALNAC3
uniprot id: A0A6P5B2J7
uniprot id: A0A6P5BHP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:ACAA2
gene id: 9915:ACAA2
uniprot id: A0A6P5DVP9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

9915:TFRC
gene id: 9915:TFRC
uniprot id: A0A6P5B2L5
uniprot id: A0A6P5BP27
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

9915:LOC109561036
gene id: 9915:LOC109561036
uniprot id: A0A6P5C1B2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RTN4
gene id: 9915:RTN4
uniprot id: A0A6P5CI57
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:ODF2
gene id: 9915:ODF2
uniprot id: A0A6P5CK84
uniprot id: A0A6P5CK90
uniprot id: A0A6P5CLI1
uniprot id: A0A6P5CLJ1
uniprot id: A0A6P5CLY5
uniprot id: A0A6P5CLY9
uniprot id: A0A6P5CMN1
uniprot id: A0A6P5CNM8
uniprot id: A0A6P5CNN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

9915:SPRY2
gene id: 9915:SPRY2
uniprot id: A0A6P5CPJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: ruffle membrane

9915:PTGR2
gene id: 9915:PTGR2
uniprot id: A0A6P5CGD5
uniprot id: A0A6P5CIM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

9915:LOC109555716
gene id: 9915:LOC109555716
uniprot id: A0A6P5B071
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:HPCAL4
gene id: 9915:HPCAL4
uniprot id: A0A6P5B491
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.

9915:POLR3G
gene id: 9915:POLR3G
uniprot id: A0A6P5C5U6
uniprot id: A0A6P5C5Y1
uniprot id: A0A6P5C6A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

9915:ZNF24
gene id: 9915:ZNF24
uniprot id: A0A6P5DV05
uniprot id: A0A6P5DVZ3
uniprot id: A0A6P5DYG1
names: Subcellular Location Annotation
messages: Nucleus

9915:MEF2A
gene id: 9915:MEF2A
uniprot id: A0A6P5DMI6
uniprot id: A0A6P5DPJ0
uniprot id: A0A6P5DPW3
uniprot id: A0A6P5DPW7
names: Subcellular Location Annotation
messages: Nucleus

9915:MAGI3
gene id: 9915:MAGI3
uniprot id: A0A6P5B676
uniprot id: A0A6P5BGZ2
uniprot id: A0A6P5BNC0
uniprot id: A0A6P5BND7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9915:GPR137C
gene id: 9915:GPR137C
uniprot id: A0A6P5CCW6
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

9915:LOC109555762
gene id: 9915:LOC109555762
uniprot id: A0A6P5BGP3
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:CSNK1E
gene id: 9915:CSNK1E
uniprot id: A0A6P5BW47
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:JAK3
gene id: 9915:JAK3
uniprot id: A0A6P5C1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system

9915:PREPL
gene id: 9915:PREPL
uniprot id: A0A6P5CL71
names: Similarity
messages: Belongs to the peptidase S9A family.

9915:FXYD1
gene id: 9915:FXYD1
uniprot id: A0A6P5D8Z6
uniprot id: A0A6P5DAS0
names: Similarity
messages: Belongs to the FXYD family.

9915:GDF2
gene id: 9915:GDF2
uniprot id: A0A6P5BB46
names: Similarity
messages: Belongs to the TGF-beta family.

9915:DYNLRB2
gene id: 9915:DYNLRB2
uniprot id: A0A6P5DEB3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs); the composition seems to vary in respect to the IC, LIC and LC composition. The heavy chain homodimer serves as a scaffold for the probable homodimeric assembly of the respective non-catalytic subunits. The ICs and LICs bind directly to the HC dimer and the LCs assemble on the IC dimer.
messages: cytoskeleton

9915:SLC16A11
gene id: 9915:SLC16A11
uniprot id: A0A6P5DKI3
names: Subcellular Location Annotation
messages: Membrane

9915:ENY2
gene id: 9915:ENY2
uniprot id: A0A6P5CUW3
uniprot id: A0A6P5CW46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3. TREX-2 contains 2 ENY2 chains. The TREX-2 complex interacts with the nucleoporin NUP153. Component of some SAGA transcription coactivator-HAT complexes, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ENY2, ATXN7, ATXN7L3, and USP22 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with ATXN7L3, GANP and with the RNA polymerase II. Interacts strongly with ATXN7L3 and ATXN7L3B.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.
messages: nucleoplasm

9915:GRIN2B
gene id: 9915:GRIN2B
uniprot id: A0A6P5BV11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

9915:ARR3
gene id: 9915:ARR3
uniprot id: A0A6P5BEJ3
names: Function
names: Similarity
messages: Belongs to the arrestin family.
messages: May play a role in an as yet undefined retina-specific signal transduction. Could bind to photoactivated-phosphorylated red/green opsins.

9915:ME2
gene id: 9915:ME2
uniprot id: A0A6P5DYZ6
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

9915:POLE2
gene id: 9915:POLE2
uniprot id: A0A6P5CEN4
uniprot id: A0A6P5CFT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus
messages: Participates in DNA repair and in chromosomal DNA replication.

9915:AGPS
gene id: 9915:AGPS
uniprot id: A0A6P5CJH6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
messages: Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids.
messages: Homodimer.
messages: Peroxisome

9915:TRPM4
gene id: 9915:TRPM4
uniprot id: A0A6P5D746
uniprot id: A0A6P5DAM2
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569970
gene id: 9915:LOC109569970
uniprot id: A0A6P5D2X3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DSC1
gene id: 9915:DSC1
uniprot id: A0A6P5DZT2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9915:LOC109569464
gene id: 9915:LOC109569464
uniprot id: A0A6P5CZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CRP
gene id: 9915:CRP
uniprot id: A0A6P5E0U8
uniprot id: A0A6P5E3B2
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pentraxin family.
messages: Binds 2 calcium ions per subunit.
messages: Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:EHD3
gene id: 9915:EHD3
uniprot id: A0A6P5CKN2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

9915:LOC109577695
gene id: 9915:LOC109577695
uniprot id: A0A6P5DUI3
names: Similarity
messages: Belongs to the serpin family.

9915:UBR3
gene id: 9915:UBR3
uniprot id: A0A6P5CPB8
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

9915:LOC109574857
gene id: 9915:LOC109574857
uniprot id: A0A6P5DMI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

9915:HTR1E
gene id: 9915:HTR1E
uniprot id: A0A6P5CAD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:ADGRL3
gene id: 9915:ADGRL3
uniprot id: A0A6P5BYI6
uniprot id: A0A6P5BYI9
uniprot id: A0A6P5BYJ5
uniprot id: A0A6P5BYY2
uniprot id: A0A6P5BZE8
names: Subcellular Location Annotation
messages: Membrane

9915:NUBPL
gene id: 9915:NUBPL
uniprot id: A0A6P5DM61
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

9915:LOC109556818
gene id: 9915:LOC109556818
uniprot id: A0A6P5BQ53
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:NAPA
gene id: 9915:NAPA
uniprot id: A0A6P5DD57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

9915:LOC109558782
gene id: 9915:LOC109558782
uniprot id: A0A6P5BBN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:B3GAT2
gene id: 9915:B3GAT2
uniprot id: A0A6P5CB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:SNRPA
gene id: 9915:SNRPA
uniprot id: A0A6P5D9J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM U1 A/B'' family.
messages: Nucleus

9915:LOC109554865
gene id: 9915:LOC109554865
uniprot id: A0A6P5B254
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF1 family.
messages: Nucleus

9915:NLE1
gene id: 9915:NLE1
uniprot id: A0A6P5DL30
uniprot id: A0A6P5DLM9
names: Subcellular Location Annotation
messages: nucleolus

9915:LOC109558453
gene id: 9915:LOC109558453
uniprot id: A0A6P5BAW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109577388
gene id: 9915:LOC109577388
uniprot id: A0A6P5DXT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus

9915:LOC109569576
gene id: 9915:LOC109569576
uniprot id: A0A6P5CY32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:COLGALT1
gene id: 9915:COLGALT1
uniprot id: A0A6P5C2I9
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

9915:RNFT1
gene id: 9915:RNFT1
uniprot id: A0A6P5DEL1
names: Subcellular Location Annotation
messages: Membrane

9915:AHR
gene id: 9915:AHR
uniprot id: A0A6P5B6I3
names: Subcellular Location Annotation
messages: Cytoplasm

9915:TAPT1
gene id: 9915:TAPT1
uniprot id: A0A6P5BZE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

9915:SEMA4F
gene id: 9915:SEMA4F
uniprot id: A0A6P5CHH6
uniprot id: A0A6P5CIE3
uniprot id: A0A6P5CKI7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109554069
gene id: 9915:LOC109554069
uniprot id: A0A6P5BBE6
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

9915:LOC109577629
gene id: 9915:LOC109577629
uniprot id: A0A6P5DY25
names: Subcellular Location Annotation
messages: Nucleus

9915:ATP1B2
gene id: 9915:ATP1B2
uniprot id: A0A6P5DIG2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

9915:RRM1
gene id: 9915:RRM1
uniprot id: A0A6P5CZ17
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

9915:LOC109577003
gene id: 9915:LOC109577003
uniprot id: A0A6P5DSJ0
names: Similarity
messages: Belongs to the alkaline phosphatase family.

9915:SLC15A5
gene id: 9915:SLC15A5
uniprot id: A0A6P5BME8
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

9915:COPA
gene id: 9915:COPA
uniprot id: A0A6P5DZT8
uniprot id: A0A6P5E2W1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

9915:PON3
gene id: 9915:PON3
uniprot id: A0A6P5BRS6
names: Cofactor
names: Similarity
messages: Belongs to the paraoxonase family.
messages: Binds 2 calcium ions per subunit.

9915:LOC109568916
gene id: 9915:LOC109568916
uniprot id: A0A6P5CXF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:NRDC
gene id: 9915:NRDC
uniprot id: A0A6P5BI53
names: Similarity
messages: Belongs to the peptidase M16 family.

9915:B9D1
gene id: 9915:B9D1
uniprot id: A0A6P5DIM1
names: Subcellular Location Annotation
messages: cilium basal body

9915:LOC109562114
gene id: 9915:LOC109562114
uniprot id: A0A6P5C676
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: cytoskeleton

9915:CAMK2D
gene id: 9915:CAMK2D
uniprot id: A0A6P5BX07
uniprot id: A0A6P5BX09
uniprot id: A0A6P5BX11
uniprot id: A0A6P5BX27
uniprot id: A0A6P5BXH5
uniprot id: A0A6P5BXI0
uniprot id: A0A6P5BXR7
uniprot id: A0A6P5BXS3
uniprot id: A0A6P5BXT1
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

9915:ESRRB
gene id: 9915:ESRRB
uniprot id: A0A6P5CCB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

9915:LOC109576479
gene id: 9915:LOC109576479
uniprot id: A0A6P5DS47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

9915:PGAP2
gene id: 9915:PGAP2
uniprot id: A0A6P5CVJ4
uniprot id: A0A6P5CWE5
uniprot id: A0A6P5CWN2
uniprot id: A0A6P5CY31
uniprot id: A0A6P5CYY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PGAP2 family.
messages: Interacts with PGAP2IP.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

9915:LOC109557879
gene id: 9915:LOC109557879
uniprot id: A0A6P5BD68
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

9915:TMOD3
gene id: 9915:TMOD3
uniprot id: A0A6P5CG24
uniprot id: A0A6P5CHK2
names: Subcellular Location Annotation
messages: cytoskeleton

9915:LOC109558013
gene id: 9915:LOC109558013
uniprot id: A0A6P5BRL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:WNT9A
gene id: 9915:WNT9A
uniprot id: A0A6P5BZV6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:HMX1
gene id: 9915:HMX1
uniprot id: A0A6P5BWR9
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109558465
gene id: 9915:LOC109558465
uniprot id: A0A6P5BRY4
names: Subcellular Location Annotation
messages: Membrane

9915:CAPZB
gene id: 9915:CAPZB
uniprot id: A0A6P5DIH7
uniprot id: A0A6P5DLP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

9915:SLC46A2
gene id: 9915:SLC46A2
uniprot id: A0A6P5C9B8
names: Subcellular Location Annotation
messages: Membrane

9915:NSMCE2
gene id: 9915:NSMCE2
uniprot id: A0A6P5CUJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

9915:PPP2R5A
gene id: 9915:PPP2R5A
uniprot id: A0A6P5D502
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

9915:MST1R
gene id: 9915:MST1R
uniprot id: A0A6P5DS14
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:ADCY8
gene id: 9915:ADCY8
uniprot id: A0A6P5CV78
uniprot id: A0A6P5CVG6
uniprot id: A0A6P5CWT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

9915:FAM83G
gene id: 9915:FAM83G
uniprot id: A0A6P5DFJ1
names: Similarity
messages: Belongs to the FAM83 family.

9915:ALDH5A1
gene id: 9915:ALDH5A1
uniprot id: A0A6P5DX47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
messages: Homotetramer.
messages: Mitochondrion

9915:TMEM258
gene id: 9915:TMEM258
uniprot id: A0A6P5BKP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST5 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

9915:CDKN2AIP
gene id: 9915:CDKN2AIP
uniprot id: A0A6P5BHH6
uniprot id: A0A6P5BHW9
names: Similarity
messages: Belongs to the CARF family.

9915:METTL10
gene id: 9915:METTL10
uniprot id: A0A6P5AV65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: Nucleus
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'.

9915:ATP5B
gene id: 9915:ATP5B
uniprot id: A0A6P5BTL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

9915:SEZ6L2
gene id: 9915:SEZ6L2
uniprot id: A0A6P5DWN8
uniprot id: A0A6P5DWP2
uniprot id: A0A6P5DXQ6
uniprot id: A0A6P5E0C9
uniprot id: A0A6P5E0V6
uniprot id: A0A6P5E0W1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:FTL
gene id: 9915:FTL
uniprot id: A0A6P5DXS9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9915:IL18R1
gene id: 9915:IL18R1
uniprot id: A0A6P5CIB9
uniprot id: A0A6P5CJG6
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

9915:DAO
gene id: 9915:DAO
uniprot id: A0A6P5D5V3
uniprot id: A0A6P5D7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

9915:PKD1L2
gene id: 9915:PKD1L2
uniprot id: A0A6P5D5Y1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:CHRNB3
gene id: 9915:CHRNB3
uniprot id: A0A6P5B8Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:LOC109573158
gene id: 9915:LOC109573158
uniprot id: A0A6P5DEN7
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DBR1
gene id: 9915:DBR1
uniprot id: A0A6P5BWW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

9915:LOC109560984
gene id: 9915:LOC109560984
uniprot id: A0A6P5C066
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:LOC109572441
gene id: 9915:LOC109572441
uniprot id: A0A6P5DBD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CDS2
gene id: 9915:CDS2
uniprot id: A0A6P5CSC6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

9915:TUBD1
gene id: 9915:TUBD1
uniprot id: A0A6P5DID2
uniprot id: A0A6P5DJN5
uniprot id: A0A6P5DLI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tubulin family.
messages: Nucleus
messages: centriole
messages: cilium

9915:KIAA0430
gene id: 9915:KIAA0430
uniprot id: A0A6P5DY21
uniprot id: A0A6P5E0Q3
names: Subcellular Location Annotation
messages: Peroxisome

9915:POLR3D
gene id: 9915:POLR3D
uniprot id: A0A6P5C8G8
uniprot id: A0A6P5C8P2
names: Subcellular Location Annotation
messages: Nucleus

9915:FAT2
gene id: 9915:FAT2
uniprot id: A0A6P5C5V4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109564317
gene id: 9915:LOC109564317
uniprot id: A0A6P5CCH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PPIP5K1
gene id: 9915:PPIP5K1
uniprot id: A0A6P5DLB4
uniprot id: A0A6P5DLB8
uniprot id: A0A6P5DM08
uniprot id: A0A6P5DM13
uniprot id: A0A6P5DMR4
uniprot id: A0A6P5DMS0
uniprot id: A0A6P5DPQ5
uniprot id: A0A6P5DPR0
uniprot id: A0A6P5DQ24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

9915:RPL26
gene id: 9915:RPL26
uniprot id: A0A6P5DHH6
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

9915:LOC109576630
gene id: 9915:LOC109576630
uniprot id: A0A6P5DUU7
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:ASZ1
gene id: 9915:ASZ1
uniprot id: A0A6P5BBJ1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:LOC109558713
gene id: 9915:LOC109558713
uniprot id: A0A6P5BS73
names: Function
names: Similarity
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

9915:B4GALT4
gene id: 9915:B4GALT4
uniprot id: A0A6P5DV30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9915:PACS1
gene id: 9915:PACS1
uniprot id: A0A6P5AUW2
names: Similarity
messages: Belongs to the PACS family.

9915:LOC109575136
gene id: 9915:LOC109575136
uniprot id: A0A6P5DKV3
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109566074
gene id: 9915:LOC109566074
uniprot id: A0A6P5CI47
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9915:LOC109575889
gene id: 9915:LOC109575889
uniprot id: A0A6P5DNF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:AGRP
gene id: 9915:AGRP
uniprot id: A0A6P5D823
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:B4GAT1
gene id: 9915:B4GAT1
uniprot id: A0A6P5BKA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 49 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:CBFA2T3
gene id: 9915:CBFA2T3
uniprot id: A0A6P5D9H5
uniprot id: A0A6P5DB86
uniprot id: A0A6P5DCP4
names: Similarity
messages: Belongs to the CBFA2T family.

9915:LOC109569101
gene id: 9915:LOC109569101
uniprot id: A0A6P5CW62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SMARCB1
gene id: 9915:SMARCB1
uniprot id: A0A6P5D303
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

9915:LOC109558865
gene id: 9915:LOC109558865
uniprot id: A0A6P5BSC5
names: Similarity
messages: Belongs to the histone H2B family.

9915:CD40LG
gene id: 9915:CD40LG
uniprot id: A0A6P5AZL6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a ligand for integrins, specifically ITGA5:ITGB1 and ITGAV:ITGB3; both integrins and the CD40 receptor are required for activation of CD40-CD40LG signaling, which have cell-type dependent effects, such as B-cell activation, NF-kappa-B signaling and anti-apoptotic signaling.
messages: Belongs to the tumor necrosis factor family.
messages: Cell surface
messages: Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
messages: Homotrimer.

9915:LOC109564652
gene id: 9915:LOC109564652
uniprot id: A0A6P5CD63
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9915:PSMA6
gene id: 9915:PSMA6
uniprot id: A0A6P5DNC1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9915:INTS13
gene id: 9915:INTS13
uniprot id: A0A6P5BUZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

9915:DMRT3
gene id: 9915:DMRT3
uniprot id: A0A6P5C648
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9915:LOC109566362
gene id: 9915:LOC109566362
uniprot id: A0A6P5CL47
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:CAPNS1
gene id: 9915:CAPNS1
uniprot id: A0A6P5D8T3
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer or heterodimer of a large (catalytic) and a small (regulatory) subunit. In presence of calcium, the heterodimer dissociates.
messages: Membrane

9915:CDC73
gene id: 9915:CDC73
uniprot id: A0A6P5D1N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

9915:DAP3
gene id: 9915:DAP3
uniprot id: A0A6P5AXS0
uniprot id: A0A6P5BHR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

9915:LOC109562540
gene id: 9915:LOC109562540
uniprot id: A0A6P5C7R7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:GALNT2
gene id: 9915:GALNT2
uniprot id: A0A6P5B9H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109563043
gene id: 9915:LOC109563043
uniprot id: A0A6P5C7Z0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:IDH3G
gene id: 9915:IDH3G
uniprot id: A0A6P5AXD6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

9915:LOC109565617
gene id: 9915:LOC109565617
uniprot id: A0A6P5CJK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558815
gene id: 9915:LOC109558815
uniprot id: A0A6P5BMF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:NLRP13
gene id: 9915:NLRP13
uniprot id: A0A6P5D884
names: Similarity
messages: Belongs to the NLRP family.

9915:CACNG2
gene id: 9915:CACNG2
uniprot id: A0A6P5BME2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

9915:LYNX1
gene id: 9915:LYNX1
uniprot id: A0A6P5CWQ7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:FAM57A
gene id: 9915:FAM57A
uniprot id: A0A6P5DDG4
uniprot id: A0A6P5DDH3
uniprot id: A0A6P5DF81
uniprot id: A0A6P5DFU8
names: Subcellular Location Annotation
messages: Membrane

9915:OTOG
gene id: 9915:OTOG
uniprot id: A0A6P5D0B9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ADGRV1
gene id: 9915:ADGRV1
uniprot id: A0A6P5C0S5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109564586
gene id: 9915:LOC109564586
uniprot id: A0A6P5CCZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:B3GALT1
gene id: 9915:B3GALT1
uniprot id: A0A6P5CPD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:TNRC6B
gene id: 9915:TNRC6B
uniprot id: A0A6P5BVX1
uniprot id: A0A6P5BVZ7
uniprot id: A0A6P5BW97
names: Similarity
messages: Belongs to the GW182 family.

9915:ALKBH5
gene id: 9915:ALKBH5
uniprot id: A0A6P5DI99
names: Subcellular Location Annotation
names: Subunit
messages: Monomer.
messages: Nucleus speckle

9915:CPB1
gene id: 9915:CPB1
uniprot id: A0A6P5CDM0
names: Similarity
messages: Belongs to the peptidase M14 family.

9915:MRPS24
gene id: 9915:MRPS24
uniprot id: A0A6P5CL57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Mitochondrion

9915:GALNTL6
gene id: 9915:GALNTL6
uniprot id: A0A6P5C6Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109573225
gene id: 9915:LOC109573225
uniprot id: A0A6P5DCI3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ABHD2
gene id: 9915:ABHD2
uniprot id: A0A6P5DM05
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

9915:MCRIP2
gene id: 9915:MCRIP2
uniprot id: A0A6P5DXG5
uniprot id: A0A6P5DYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

9915:LOC109562653
gene id: 9915:LOC109562653
uniprot id: A0A6P5C6Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:GGT6
gene id: 9915:GGT6
uniprot id: A0A6P5DFY8
names: Similarity
messages: Belongs to the gamma-glutamyltransferase family.

9915:ARMCX3
gene id: 9915:ARMCX3
uniprot id: A0A6P5BLP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eutherian X-chromosome-specific Armcx family.
messages: Membrane

9915:LOC109560134
gene id: 9915:LOC109560134
uniprot id: A0A6P5BX88
names: Similarity
messages: Belongs to the histone H2B family.

9915:SIAH1
gene id: 9915:SIAH1
uniprot id: A0A6P5DAB8
uniprot id: A0A6P5DCM4
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9915:SAR1B
gene id: 9915:SAR1B
uniprot id: A0A6P5C4W5
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

9915:PRICKLE3
gene id: 9915:PRICKLE3
uniprot id: A0A6P5BMA0
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9915:LOC109555624
gene id: 9915:LOC109555624
uniprot id: A0A6P5BMW8
names: Subcellular Location Annotation
messages: Nucleus

9915:HACD4
gene id: 9915:HACD4
uniprot id: A0A6P5C7N0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:VEGFA
gene id: 9915:VEGFA
uniprot id: A0A6P5DSA3
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

9915:KRT7
gene id: 9915:KRT7
uniprot id: A0A6P5BSS3
names: Similarity
messages: Belongs to the intermediate filament family.

9915:SMC1B
gene id: 9915:SMC1B
uniprot id: A0A6P5BBV8
uniprot id: A0A6P5BSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

9915:FAM210B
gene id: 9915:FAM210B
uniprot id: A0A6P5CRF3
names: Similarity
messages: Belongs to the FAM210 family.

9915:P2RY4
gene id: 9915:P2RY4
uniprot id: A0A6P5BLB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:BCL7C
gene id: 9915:BCL7C
uniprot id: A0A6P5DWI7
names: Similarity
messages: Belongs to the BCL7 family.

9915:LOC109556699
gene id: 9915:LOC109556699
uniprot id: A0A6P5BJ62
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM63A
gene id: 9915:FAM63A
uniprot id: A0A6P5BLT1
uniprot id: A0A6P5BLT7
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

9915:F5
gene id: 9915:F5
uniprot id: A0A6P5D2G9
names: Similarity
messages: Belongs to the multicopper oxidase family.

9915:LOC109577406
gene id: 9915:LOC109577406
uniprot id: A0A6P5DXU6
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109555728
gene id: 9915:LOC109555728
uniprot id: A0A6P5BN20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:LOC109555736
gene id: 9915:LOC109555736
uniprot id: A0A6P5B086
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:CTNNBL1
gene id: 9915:CTNNBL1
uniprot id: A0A6P5CRT9
names: Subcellular Location Annotation
messages: Nucleus

9915:CAPZA3
gene id: 9915:CAPZA3
uniprot id: A0A6P5BSA3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9915:BEST3
gene id: 9915:BEST3
uniprot id: A0A6P5BT22
uniprot id: A0A6P5BT27
uniprot id: A0A6P5BT28
uniprot id: A0A6P5BT29
uniprot id: A0A6P5BT31
uniprot id: A0A6P5BT32
uniprot id: A0A6P5BT33
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109554787
gene id: 9915:LOC109554787
uniprot id: A0A6P5B209
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:FA2H
gene id: 9915:FA2H
uniprot id: A0A6P5DEH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters in sebaceous gland, specifically regulating hair follicle homeostasis. Involved in the synthesis of sphingolipids of plasma membrane rafts, controlling lipid raft mobility and trafficking of raft-associated proteins.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:PHACTR1
gene id: 9915:PHACTR1
uniprot id: A0A6P5DTH4
uniprot id: A0A6P5DTU7
uniprot id: A0A6P5DUS5
uniprot id: A0A6P5DX96
uniprot id: A0A6P5DXM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

9915:CDCA2
gene id: 9915:CDCA2
uniprot id: A0A6P5C9W3
names: Subcellular Location Annotation
messages: Nucleus

9915:MAL
gene id: 9915:MAL
uniprot id: A0A6P5CGV7
names: Subcellular Location Annotation
messages: Membrane

9915:PLPP3
gene id: 9915:PLPP3
uniprot id: A0A6P5B7U3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9915:RNASE2
gene id: 9915:RNASE2
uniprot id: A0A6P5CCR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pancreatic ribonuclease family.
messages: Secreted

9915:LOC109562642
gene id: 9915:LOC109562642
uniprot id: A0A6P5C6K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:GCNT1
gene id: 9915:GCNT1
uniprot id: A0A6P5C7T0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

9915:SSPO
gene id: 9915:SSPO
uniprot id: A0A6P5BRI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular space

9915:NR1D1
gene id: 9915:NR1D1
uniprot id: A0A6P5DEB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:AIG1
gene id: 9915:AIG1
uniprot id: A0A6P5CC93
uniprot id: A0A6P5CCN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIG1 family.
messages: Membrane

9915:C25H16orf71
gene id: 9915:C25H16orf71
uniprot id: A0A6P5E011
uniprot id: A0A6P5E300
names: Function
messages: In cyliated cells, dynein axonemal particle-specific protein required for deployment of ODA to the axoneme. Interacts with outer dynein arm (ODA) subunits.

9915:DNASE1
gene id: 9915:DNASE1
uniprot id: A0A6P5DYR8
uniprot id: A0A6P5E1F1
uniprot id: A0A6P5E1F6
uniprot id: A0A6P5E1X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9915:TMBIM6
gene id: 9915:TMBIM6
uniprot id: A0A6P5BDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

9915:PDE1B
gene id: 9915:PDE1B
uniprot id: A0A6P5BF99
uniprot id: A0A6P5BMW9
uniprot id: A0A6P5BSK9
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:LOC109555606
gene id: 9915:LOC109555606
uniprot id: A0A6P5BMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

9915:COQ4
gene id: 9915:COQ4
uniprot id: A0A6P5CK75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

9915:VAT1
gene id: 9915:VAT1
uniprot id: A0A6P5DHW1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9915:LOC109560658
gene id: 9915:LOC109560658
uniprot id: A0A6P5BZ92
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:IGF2BP1
gene id: 9915:IGF2BP1
uniprot id: A0A6P5DD93
uniprot id: A0A6P5DDA6
uniprot id: A0A6P5DGE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: P-body
messages: Stress granule
messages: filopodium
messages: lamellipodium

9915:LCN10
gene id: 9915:LCN10
uniprot id: A0A6P5CI75
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

9915:USP30
gene id: 9915:USP30
uniprot id: A0A6P5D8J0
names: Function
names: Similarity
messages: Belongs to the peptidase C19 family.
messages: Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes.

9915:SNX17
gene id: 9915:SNX17
uniprot id: A0A6P5CJ61
uniprot id: A0A6P5CMF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome
messages: Membrane

9915:NAT9
gene id: 9915:NAT9
uniprot id: A0A6P5DFX9
uniprot id: A0A6P5DHJ1
uniprot id: A0A6P5DIV6
names: Similarity
messages: Belongs to the acetyltransferase family. GNAT subfamily.

9915:LOC109569116
gene id: 9915:LOC109569116
uniprot id: A0A6P5CWG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PDSS2
gene id: 9915:PDSS2
uniprot id: A0A6P5CBD8
uniprot id: A0A6P5CCH4
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

9915:POLD3
gene id: 9915:POLD3
uniprot id: A0A6P5CZE3
uniprot id: A0A6P5CZR3
uniprot id: A0A6P5D189
names: Subcellular Location Annotation
messages: Nucleus

9915:MARK2
gene id: 9915:MARK2
uniprot id: A0A6P5AUK1
uniprot id: A0A6P5AUK6
uniprot id: A0A6P5AUL2
uniprot id: A0A6P5B0P7
uniprot id: A0A6P5B0Q3
uniprot id: A0A6P5B0Q8
uniprot id: A0A6P5B0R2
uniprot id: A0A6P5BCT9
uniprot id: A0A6P5BK09
uniprot id: A0A6P5BK12
uniprot id: A0A6P5BK15
uniprot id: A0A6P5BK63
uniprot id: A0A6P5BK66
uniprot id: A0A6P5BK69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

9915:GSS
gene id: 9915:GSS
uniprot id: A0A6P5CQA0
uniprot id: A0A6P5CRK7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

9915:OSTC
gene id: 9915:OSTC
uniprot id: A0A6P5BXW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. May be involved in N-glycosylation of APP (amyloid-beta precursor protein). Can modulate gamma-secretase cleavage of APP by enhancing endoprotelysis of PSEN1.

9915:LOC109554125
gene id: 9915:LOC109554125
uniprot id: A0A6P5ATB4
names: Similarity
messages: Belongs to the RASGRP family.

9915:LOC109569074
gene id: 9915:LOC109569074
uniprot id: A0A6P5CWE7
uniprot id: A0A6P5CYQ6
names: Similarity
messages: Belongs to the GroES chaperonin family.

9915:FNIP2
gene id: 9915:FNIP2
uniprot id: A0A6P5D6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

9915:ING3
gene id: 9915:ING3
uniprot id: A0A6P5B7Z7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9915:SUCLA2
gene id: 9915:SUCLA2
uniprot id: A0A6P5CNL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

9915:PCYT1B
gene id: 9915:PCYT1B
uniprot id: A0A6P5B4N4
uniprot id: A0A6P5BMH2
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

9915:PPA2
gene id: 9915:PPA2
uniprot id: A0A6P5BWP5
names: Similarity
messages: Belongs to the PPase family.

9915:MEGF11
gene id: 9915:MEGF11
uniprot id: A0A6P5CD95
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:AMACR
gene id: 9915:AMACR
uniprot id: A0A6P5DK29
names: Similarity
messages: Belongs to the CoA-transferase III family.

9915:ENO2
gene id: 9915:ENO2
uniprot id: A0A6P5BC81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

9915:CDK5R1
gene id: 9915:CDK5R1
uniprot id: A0A6P5DIG6
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

9915:LOC109553290
gene id: 9915:LOC109553290
uniprot id: A0A6P5BHF3
names: Similarity
messages: Belongs to the FAM90 family.

9915:MAP3K13
gene id: 9915:MAP3K13
uniprot id: A0A6P5B6H4
names: Function
names: Similarity
messages: Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7.
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

9915:PFKFB3
gene id: 9915:PFKFB3
uniprot id: A0A6P5CQZ3
uniprot id: A0A6P5CS52
uniprot id: A0A6P5CSF0
uniprot id: A0A6P5CTE8
uniprot id: A0A6P5CUF2
uniprot id: A0A6P5CUF6
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

9915:TYRO3
gene id: 9915:TYRO3
uniprot id: A0A6P5CEI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane

9915:IPO7
gene id: 9915:IPO7
uniprot id: A0A6P5CY77
names: Subcellular Location Annotation
messages: Cytoplasm

9915:ALOX12
gene id: 9915:ALOX12
uniprot id: A0A6P5DG92
uniprot id: A0A6P5DJ54
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MEAF6
gene id: 9915:MEAF6
uniprot id: A0A6P5BPN6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. Component of HBO1 complexes, which specifically mediate acetylation of histone H3 at 'Lys-14' (H3K14ac), and have reduced activity toward histone H4. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity.
messages: Component of the NuA4 histone acetyltransferase complex. Component of the hbo1 complex. Component of the moz/morf complex.
messages: kinetochore
messages: nucleolus

9915:FOXL2
gene id: 9915:FOXL2
uniprot id: A0A6P5BVQ7
names: Subcellular Location Annotation
messages: Nucleus

9915:STX1B
gene id: 9915:STX1B
uniprot id: A0A6P5DWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntaxin family.
messages: Membrane

9915:LOC109554237
gene id: 9915:LOC109554237
uniprot id: A0A6P5BJB3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TSPYL6
gene id: 9915:TSPYL6
uniprot id: A0A6P5CH11
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:LOC109559268
gene id: 9915:LOC109559268
uniprot id: A0A6P5BT84
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

9915:TEAD1
gene id: 9915:TEAD1
uniprot id: A0A6P5CW58
uniprot id: A0A6P5CW63
uniprot id: A0A6P5CX09
uniprot id: A0A6P5CX13
uniprot id: A0A6P5CX43
uniprot id: A0A6P5CYN6
names: Subcellular Location Annotation
messages: Nucleus

9915:MRPL10
gene id: 9915:MRPL10
uniprot id: A0A6P5DFW9
uniprot id: A0A6P5DHH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

9915:LOC109576706
gene id: 9915:LOC109576706
uniprot id: A0A6P5DRB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MAU2
gene id: 9915:MAU2
uniprot id: A0A6P5C169
uniprot id: A0A6P5C1J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC4/mau-2 family.
messages: nucleoplasm

9915:LOC109576890
gene id: 9915:LOC109576890
uniprot id: A0A6P5DVT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:RAB11FIP3
gene id: 9915:RAB11FIP3
uniprot id: A0A6P5DYI3
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

9915:PRIM1
gene id: 9915:PRIM1
uniprot id: A0A6P5BTK5
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

9915:AHCYL1
gene id: 9915:AHCYL1
uniprot id: A0A6P5BQ13
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

9915:LOC109569356
gene id: 9915:LOC109569356
uniprot id: A0A6P5CX36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CSTB
gene id: 9915:CSTB
uniprot id: A0A6P5C1J1
names: Similarity
messages: Belongs to the cystatin family.

9915:LOC109563585
gene id: 9915:LOC109563585
uniprot id: A0A6P5CAV6
names: Similarity
messages: Belongs to the nesprin family.

9915:LOC109559068
gene id: 9915:LOC109559068
uniprot id: A0A6P5BN40
names: Similarity
messages: Belongs to the intermediate filament family.

9915:TMC8
gene id: 9915:TMC8
uniprot id: A0A6P5DGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMC family.
messages: Membrane

9915:RPS21
gene id: 9915:RPS21
uniprot id: A0A6P5CQK0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the 40S small ribosomal subunit.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum
messages: cytosol

9915:LOC109553199
gene id: 9915:LOC109553199
uniprot id: A0A6P5AWE4
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:BARX1
gene id: 9915:BARX1
uniprot id: A0A6P5C9N1
names: Subcellular Location Annotation
messages: Nucleus

9915:PER1
gene id: 9915:PER1
uniprot id: A0A6P5DFN1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:LOC109571841
gene id: 9915:LOC109571841
uniprot id: A0A6P5D855
names: Subcellular Location Annotation
messages: Membrane

9915:UTRN
gene id: 9915:UTRN
uniprot id: A0A6P5C9T6
names: Subcellular Location Annotation
messages: cytoskeleton

9915:PAPOLA
gene id: 9915:PAPOLA
uniprot id: A0A6P5DKU7
uniprot id: A0A6P5DKV1
uniprot id: A0A6P5DLF6
uniprot id: A0A6P5DM59
uniprot id: A0A6P5DP37
uniprot id: A0A6P5DPH8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

9915:CXCL16
gene id: 9915:CXCL16
uniprot id: A0A6P5DHJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Membrane

9915:LOC109570327
gene id: 9915:LOC109570327
uniprot id: A0A6P5D0F3
uniprot id: A0A6P5D434
names: Similarity
messages: Belongs to the DDI1 family.

9915:LOC109558700
gene id: 9915:LOC109558700
uniprot id: A0A6P5BBG8
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:EGFL8
gene id: 9915:EGFL8
uniprot id: A0A6P5DS10
uniprot id: A0A6P5DVI1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109569088
gene id: 9915:LOC109569088
uniprot id: A0A6P5CVA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ETV3L
gene id: 9915:ETV3L
uniprot id: A0A6P5BJI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:TSPYL1
gene id: 9915:TSPYL1
uniprot id: A0A6P5CC86
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:TERF2
gene id: 9915:TERF2
uniprot id: A0A6P5D6Z5
uniprot id: A0A6P5D8L6
names: Subcellular Location Annotation
messages: telomere

9915:GPR31
gene id: 9915:GPR31
uniprot id: A0A6P5CDS8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:SLC37A3
gene id: 9915:SLC37A3
uniprot id: A0A6P5B8L4
uniprot id: A0A6P5BCL3
uniprot id: A0A6P5BKT8
uniprot id: A0A6P5BR55
uniprot id: A0A6P5BR87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9915:MDN1
gene id: 9915:MDN1
uniprot id: A0A6P5CAW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

9915:NGB
gene id: 9915:NGB
uniprot id: A0A6P5CDP7
names: Similarity
messages: Belongs to the globin family.

9915:MICAL3
gene id: 9915:MICAL3
uniprot id: A0A6P5BVN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mical family.
messages: Nucleus
messages: cytoskeleton

9915:SERPINA4
gene id: 9915:SERPINA4
uniprot id: A0A6P5DNL8
names: Similarity
messages: Belongs to the serpin family.

9915:LOC109562844
gene id: 9915:LOC109562844
uniprot id: A0A6P5C728
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:RABGGTB
gene id: 9915:RABGGTB
uniprot id: A0A6P5BA77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

9915:CSGALNACT2
gene id: 9915:CSGALNACT2
uniprot id: A0A6P5ARM4
uniprot id: A0A6P5AY87
uniprot id: A0A6P5BI36
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:TEAD3
gene id: 9915:TEAD3
uniprot id: A0A6P5DTM1
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

9915:IFT122
gene id: 9915:IFT122
uniprot id: A0A6P5DMW1
names: Subcellular Location Annotation
messages: cilium

9915:ST7L
gene id: 9915:ST7L
uniprot id: A0A6P5B160
uniprot id: A0A6P5B168
uniprot id: A0A6P5B173
uniprot id: A0A6P5B6A7
uniprot id: A0A6P5B6B4
uniprot id: A0A6P5B6B7
uniprot id: A0A6P5BH13
uniprot id: A0A6P5BH16
uniprot id: A0A6P5BNE1
uniprot id: A0A6P5BNE4
uniprot id: A0A6P5BNG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

9915:LOC109556979
gene id: 9915:LOC109556979
uniprot id: A0A6P5B606
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RPS16
gene id: 9915:RPS16
uniprot id: A0A6P5DET4
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

9915:RDH11
gene id: 9915:RDH11
uniprot id: A0A6P5CH39
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:VOPP1
gene id: 9915:VOPP1
uniprot id: A0A6P5DQ08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VOPP1/ECOP family.
messages: Cytoplasmic vesicle membrane
messages: Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed.
messages: Membrane

9915:LOC109560080
gene id: 9915:LOC109560080
uniprot id: A0A6P5BWU3
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

9915:DIO3
gene id: 9915:DIO3
uniprot id: A0A6P5DL56
names: Function
names: Similarity
messages: Belongs to the iodothyronine deiodinase family.
messages: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine).

9915:PLIN3
gene id: 9915:PLIN3
uniprot id: A0A6P5C3A1
names: Similarity
messages: Belongs to the perilipin family.

9915:MFSD6
gene id: 9915:MFSD6
uniprot id: A0A6P5CG99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

9915:ACTR2
gene id: 9915:ACTR2
uniprot id: A0A6P5CL80
names: Similarity
messages: Belongs to the actin family.

9915:PRNP
gene id: 9915:PRNP
uniprot id: A0A6P5CTK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane

9915:LIPA
gene id: 9915:LIPA
uniprot id: A0A6P5E1K7
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

9915:SLC6A6
gene id: 9915:SLC6A6
uniprot id: A0A6P5DQ55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

9915:ANHX
gene id: 9915:ANHX
uniprot id: A0A6P5D5G0
names: Subcellular Location Annotation
messages: Nucleus

9915:FABP1
gene id: 9915:FABP1
uniprot id: A0A6P5CK12
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

9915:LOC109575664
gene id: 9915:LOC109575664
uniprot id: A0A6P5DNQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Interacts with FDX1/adrenodoxin.
messages: Mitochondrion inner membrane

9915:NKX6-2
gene id: 9915:NKX6-2
uniprot id: A0A6P5E180
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109556153
gene id: 9915:LOC109556153
uniprot id: A0A6P5B7F3
uniprot id: A0A6P5BNY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Endoplasmic reticulum membrane
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

9915:SLC19A1
gene id: 9915:SLC19A1
uniprot id: A0A6P5C0N9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Transporter that mediates the import of reduced folates.

9915:LOC109576013
gene id: 9915:LOC109576013
uniprot id: A0A6P5DRX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:PRPF18
gene id: 9915:PRPF18
uniprot id: A0A6P5CRC8
uniprot id: A0A6P5CSH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

9915:DLGAP1
gene id: 9915:DLGAP1
uniprot id: A0A6P5DYJ2
names: Similarity
messages: Belongs to the SAPAP family.

9915:CKB
gene id: 9915:CKB
uniprot id: A0A6P5DL50
names: Caution
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:IGF1
gene id: 9915:IGF1
uniprot id: A0A6P5BU27
uniprot id: A0A6P5BU33
uniprot id: A0A6P5BU34
uniprot id: A0A6P5BU35
uniprot id: A0A6P5BU37
uniprot id: A0A6P5BU40
uniprot id: A0A6P5BU42
uniprot id: A0A6P5BU44
uniprot id: A0A6P5BU50
uniprot id: A0A6P5BU68
uniprot id: A0A6P5BU75
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Forms a ternary complex with IGFR1 and ITGAV:ITGB3. Forms a ternary complex with IGFR1 and ITGA6:ITGB4.
messages: Secreted

9915:DTD2
gene id: 9915:DTD2
uniprot id: A0A6P5DMH7
uniprot id: A0A6P5DPI2
names: Similarity
messages: Belongs to the DTD family.

9915:CEP57
gene id: 9915:CEP57
uniprot id: A0A6P5CYV3
names: Similarity
messages: Belongs to the translokin family.

9915:LOC109558023
gene id: 9915:LOC109558023
uniprot id: A0A6P5BRL5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109562695
gene id: 9915:LOC109562695
uniprot id: A0A6P5C6M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GABRA4
gene id: 9915:GABRA4
uniprot id: A0A6P5BY44
uniprot id: A0A6P5BY56
uniprot id: A0A6P5BYK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:OOSP2
gene id: 9915:OOSP2
uniprot id: A0A6P5CVS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLAC1 family.
messages: Secreted

9915:AZIN2
gene id: 9915:AZIN2
uniprot id: A0A6P5D7S1
uniprot id: A0A6P5D9D0
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9915:ELOVL3
gene id: 9915:ELOVL3
uniprot id: A0A6P5E133
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL3 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

9915:TFCP2
gene id: 9915:TFCP2
uniprot id: A0A6P5BD81
uniprot id: A0A6P5BD86
uniprot id: A0A6P5BFN5
uniprot id: A0A6P5BN60
uniprot id: A0A6P5BN63
uniprot id: A0A6P5BSP8
uniprot id: A0A6P5BSQ0
uniprot id: A0A6P5BST2
uniprot id: A0A6P5BST3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

9915:AKAP4
gene id: 9915:AKAP4
uniprot id: A0A6P5AZQ3
names: Similarity
messages: Belongs to the AKAP110 family.

9915:RAB9B
gene id: 9915:RAB9B
uniprot id: A0A6P5B566
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: phagosome membrane

9915:LOC109557000
gene id: 9915:LOC109557000
uniprot id: A0A6P5BQ70
names: Similarity
messages: Belongs to the cornifin (SPRR) family.

9915:ERBIN
gene id: 9915:ERBIN
uniprot id: A0A6P5DJF2
uniprot id: A0A6P5DJF6
uniprot id: A0A6P5DJR9
uniprot id: A0A6P5DKR4
uniprot id: A0A6P5DM95
uniprot id: A0A6P5DMQ5
uniprot id: A0A6P5DMR0
names: Similarity
messages: Belongs to the LAP (LRR and PDZ) protein family.

9915:SDR16C5
gene id: 9915:SDR16C5
uniprot id: A0A6P5CWY7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:DIABLO
gene id: 9915:DIABLO
uniprot id: A0A6P5D512
uniprot id: A0A6P5D6F7
uniprot id: A0A6P5D8W0
names: Subcellular Location Annotation
messages: Mitochondrion

9915:LOC109558594
gene id: 9915:LOC109558594
uniprot id: A0A6P5BEE4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109576288
gene id: 9915:LOC109576288
uniprot id: A0A6P5DTP5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:HMGCS2
gene id: 9915:HMGCS2
uniprot id: A0A6P5BN96
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

9915:SHKBP1
gene id: 9915:SHKBP1
uniprot id: A0A6P5D7V2
names: Similarity
messages: Belongs to the KCTD3 family.

9915:IMPG2
gene id: 9915:IMPG2
uniprot id: A0A6P5CS04
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: interphotoreceptor matrix

9915:GABRB2
gene id: 9915:GABRB2
uniprot id: A0A6P5C5N0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:HOPX
gene id: 9915:HOPX
uniprot id: A0A6P5BYX2
names: Subcellular Location Annotation
messages: Nucleus

9915:TNK1
gene id: 9915:TNK1
uniprot id: A0A6P5DIX4
uniprot id: A0A6P5DK10
names: Subcellular Location Annotation
messages: Cell membrane

9915:RAB4A
gene id: 9915:RAB4A
uniprot id: A0A6P5ARP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

9915:DYNC2LI1
gene id: 9915:DYNC2LI1
uniprot id: A0A6P5CHY7
uniprot id: A0A6P5CL58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

9915:SOAT2
gene id: 9915:SOAT2
uniprot id: A0A6P5BD08
uniprot id: A0A6P5BN28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:SLIT3
gene id: 9915:SLIT3
uniprot id: A0A6P5DJ21
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:YME1L1
gene id: 9915:YME1L1
uniprot id: A0A6P5CTH3
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

9915:NDRG1
gene id: 9915:NDRG1
uniprot id: A0A6P5CW56
names: Similarity
messages: Belongs to the NDRG family.

9915:PLEKHO1
gene id: 9915:PLEKHO1
uniprot id: A0A6P5BMW0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:BFSP1
gene id: 9915:BFSP1
uniprot id: A0A6P5CU08
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

9915:BMPR1A
gene id: 9915:BMPR1A
uniprot id: A0A6P5ARM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

9915:TCHP
gene id: 9915:TCHP
uniprot id: A0A6P5D3N9
uniprot id: A0A6P5D7I6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

9915:LOC109557026
gene id: 9915:LOC109557026
uniprot id: A0A6P5BJJ8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:JAGN1
gene id: 9915:JAGN1
uniprot id: A0A6P5DU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the jagunal family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:SIX3
gene id: 9915:SIX3
uniprot id: A0A6P5CIB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

9915:PRLHR
gene id: 9915:PRLHR
uniprot id: A0A6P5E480
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:LOC109569465
gene id: 9915:LOC109569465
uniprot id: A0A6P5CXH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM151B
gene id: 9915:FAM151B
uniprot id: A0A6P5C716
names: Similarity
messages: Belongs to the FAM151 family.

9915:CIRBP
gene id: 9915:CIRBP
uniprot id: A0A6P5C4A2
uniprot id: A0A6P5C4D2
uniprot id: A0A6P5C4N8
uniprot id: A0A6P5C5N3
uniprot id: A0A6P5C5N8
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with EIF4G1. Associates with ribosomes.
messages: nucleoplasm

9915:FAM168A
gene id: 9915:FAM168A
uniprot id: A0A6P5CXZ3
uniprot id: A0A6P5CY10
uniprot id: A0A6P5CY15
uniprot id: A0A6P5CZN8
names: Similarity
messages: Belongs to the FAM168 family.

9915:CNTN1
gene id: 9915:CNTN1
uniprot id: A0A6P5BSY9
uniprot id: A0A6P5BT15
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

9915:CREBBP
gene id: 9915:CREBBP
uniprot id: A0A6P5E1G7
names: Subcellular Location Annotation
messages: Cytoplasm

9915:CYLD
gene id: 9915:CYLD
uniprot id: A0A6P5D8F6
uniprot id: A0A6P5D8G1
uniprot id: A0A6P5DA29
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

9915:LOC109570441
gene id: 9915:LOC109570441
uniprot id: A0A6P5D270
uniprot id: A0A6P5D3J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:ATP23
gene id: 9915:ATP23
uniprot id: A0A6P5BTC5
uniprot id: A0A6P5BTC6
uniprot id: A0A6P5BTD2
names: Similarity
messages: Belongs to the peptidase M76 family.

9915:PKN2
gene id: 9915:PKN2
uniprot id: A0A6P5B749
uniprot id: A0A6P5BNU1
uniprot id: A0A6P5BNW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody
messages: Nucleus

9915:LOC109569067
gene id: 9915:LOC109569067
uniprot id: A0A6P5CW39
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HVCN1
gene id: 9915:HVCN1
uniprot id: A0A6P5D6D9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

9915:FOXJ2
gene id: 9915:FOXJ2
uniprot id: A0A6P5BVA1
names: Subcellular Location Annotation
messages: Nucleus

9915:KAT7
gene id: 9915:KAT7
uniprot id: A0A6P5DI17
uniprot id: A0A6P5DIY9
uniprot id: A0A6P5DJH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9915:ETV6
gene id: 9915:ETV6
uniprot id: A0A6P5BS07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:FAH
gene id: 9915:FAH
uniprot id: A0A6P5DLZ9
names: Similarity
messages: Belongs to the FAH family.

9915:LOC109577383
gene id: 9915:LOC109577383
uniprot id: A0A6P5DUC5
names: Similarity
messages: Belongs to the histone H3 family.

9915:TPM1
gene id: 9915:TPM1
uniprot id: A0A6P5CEG0
uniprot id: A0A6P5CEG4
uniprot id: A0A6P5CF34
uniprot id: A0A6P5CFS3
uniprot id: A0A6P5CG28
uniprot id: A0A6P5CG34
uniprot id: A0A6P5CH87
uniprot id: A0A6P5CH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9915:GSKIP
gene id: 9915:GSKIP
uniprot id: A0A6P5DL87
names: Similarity
messages: Belongs to the GSKIP family.

9915:PQLC1
gene id: 9915:PQLC1
uniprot id: A0A6P5DX03
uniprot id: A0A6P5DZM8
names: Subcellular Location Annotation
messages: Membrane

9915:NARF
gene id: 9915:NARF
uniprot id: A0A6P5DG62
names: Similarity
messages: Belongs to the NARF family.

9915:RDH5
gene id: 9915:RDH5
uniprot id: A0A6P5BTV3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:ACOX3
gene id: 9915:ACOX3
uniprot id: A0A6P5BZX5
names: Similarity
messages: Belongs to the acyl-CoA oxidase family.

9915:RORB
gene id: 9915:RORB
uniprot id: A0A6P5C7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

9915:ARL6IP5
gene id: 9915:ARL6IP5
uniprot id: A0A6P5DQB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

9915:LOC109577452
gene id: 9915:LOC109577452
uniprot id: A0A6P5DYE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatotropin/prolactin family.
messages: Secreted

9915:ACBD5
gene id: 9915:ACBD5
uniprot id: A0A6P5CR12
uniprot id: A0A6P5CS67
uniprot id: A0A6P5CUH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane
messages: Peroxisome membrane

9915:DCLK1
gene id: 9915:DCLK1
uniprot id: A0A6P5CQ24
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:LRRC8D
gene id: 9915:LRRC8D
uniprot id: A0A6P5BNS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

9915:UCN2
gene id: 9915:UCN2
uniprot id: A0A6P5DU97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

9915:LOC109564432
gene id: 9915:LOC109564432
uniprot id: A0A6P5CDE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

9915:LOC109562134
gene id: 9915:LOC109562134
uniprot id: A0A6P5C4V7
uniprot id: A0A6P5C4W7
uniprot id: A0A6P5C4X2
uniprot id: A0A6P5C4X7
uniprot id: A0A6P5C4Y7
uniprot id: A0A6P5C4Z0
uniprot id: A0A6P5C4Z4
uniprot id: A0A6P5C4Z5
uniprot id: A0A6P5C4Z9
uniprot id: A0A6P5C500
uniprot id: A0A6P5C503
uniprot id: A0A6P5C506
uniprot id: A0A6P5C511
uniprot id: A0A6P5C5A7
uniprot id: A0A6P5C5B2
uniprot id: A0A6P5C5B7
uniprot id: A0A6P5C5C0
uniprot id: A0A6P5C5C5
uniprot id: A0A6P5C6A4
uniprot id: A0A6P5C6A9
uniprot id: A0A6P5C6B4
uniprot id: A0A6P5C6B8
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

9915:TRPV4
gene id: 9915:TRPV4
uniprot id: A0A6P5D8C2
names: Subcellular Location Annotation
messages: Membrane

9915:CD8A
gene id: 9915:CD8A
uniprot id: A0A6P5CIM0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109569016
gene id: 9915:LOC109569016
uniprot id: A0A6P5CW99
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569649
gene id: 9915:LOC109569649
uniprot id: A0A6P5CYS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: Cell membrane
messages: cytoskeleton

9915:UBE2B
gene id: 9915:UBE2B
uniprot id: A0A6P5C4H5
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:DYNC1I1
gene id: 9915:DYNC1I1
uniprot id: A0A6P5BDX7
uniprot id: A0A6P5BRT5
names: Similarity
messages: Belongs to the dynein intermediate chain family.

9915:XPC
gene id: 9915:XPC
uniprot id: A0A6P5DNH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPC family.
messages: Nucleus

9915:YAF2
gene id: 9915:YAF2
uniprot id: A0A6P5BSY7
uniprot id: A0A6P5BT14
names: Subcellular Location Annotation
messages: Nucleus

9915:PPP1R14C
gene id: 9915:PPP1R14C
uniprot id: A0A6P5CCV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Inhibitor of PPP1CA.
messages: Membrane

9915:BTN1A1
gene id: 9915:BTN1A1
uniprot id: A0A6P5DSW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

9915:PHACTR3
gene id: 9915:PHACTR3
uniprot id: A0A6P5CQZ1
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9915:DDIT3
gene id: 9915:DDIT3
uniprot id: A0A6P5BTH9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family.
messages: Cytoplasm
messages: Heterodimer.
messages: Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer-binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression of C/EBP regulated genes. Positively regulates the transcription of TRIB3, IL6, IL8, IL23, TNFRSF10B/DR5, PPP1R15A/GADD34, BBC3/PUMA, BCL2L11/BIM and ERO1L. Negatively regulates; expression of BCL2 and MYOD1, ATF4-dependent transcriptional activation of asparagine synthetase (ASNS), CEBPA-dependent transcriptional activation of hepcidin (HAMP) and CEBPB-mediated expression of peroxisome proliferator-activated receptor gamma (PPARG). Inhibits the canonical Wnt signaling pathway by binding to TCF7L2/TCF4, impairing its DNA-binding properties and repressing its transcriptional activity. Plays a regulatory role in the inflammatory response through the induction of caspase-11 (CASP4/CASP11) which induces the activation of caspase-1 (CASP1) and both these caspases increase the activation of pro-IL1B to mature IL1B which is involved in the inflammatory response.
messages: Nucleus
messages: Phosphorylation at serine residues by MAPK14 enhances its transcriptional activation activity while phosphorylation at serine residues by CK2 inhibits its transcriptional activation activity.
messages: Ubiquitinated, leading to its degradation by the proteasome.

9915:B4GALT2
gene id: 9915:B4GALT2
uniprot id: A0A6P5BPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

9915:SLC22A18
gene id: 9915:SLC22A18
uniprot id: A0A6P5BKP3
names: Subcellular Location Annotation
messages: Membrane

9915:ATG16L2
gene id: 9915:ATG16L2
uniprot id: A0A6P5CYH3
uniprot id: A0A6P5CZI6
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

9915:CSRNP2
gene id: 9915:CSRNP2
uniprot id: A0A6P5BD97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

9915:PNPT1
gene id: 9915:PNPT1
uniprot id: A0A6P5CJQ7
uniprot id: A0A6P5CLG0
names: Similarity
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.

9915:KLHL3
gene id: 9915:KLHL3
uniprot id: A0A6P5C5X4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

9915:SLC39A9
gene id: 9915:SLC39A9
uniprot id: A0A6P5CG47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

9915:SAMHD1
gene id: 9915:SAMHD1
uniprot id: A0A6P5CPD3
uniprot id: A0A6P5CQG9
uniprot id: A0A6P5CSY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAMHD1 family.
messages: Chromosome

9915:MVD
gene id: 9915:MVD
uniprot id: A0A6P5DE33
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

9915:LOC109564097
gene id: 9915:LOC109564097
uniprot id: A0A6P5CC54
uniprot id: A0A6P5CCP0
uniprot id: A0A6P5CD19
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

9915:LOC109562664
gene id: 9915:LOC109562664
uniprot id: A0A6P5C6P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Secreted

9915:GPR12
gene id: 9915:GPR12
uniprot id: A0A6P5CP24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:LOC109566871
gene id: 9915:LOC109566871
uniprot id: A0A6P5CQG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:OXSM
gene id: 9915:OXSM
uniprot id: A0A6P5AQV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.
messages: Mitochondrion

9915:ITGA9
gene id: 9915:ITGA9
uniprot id: A0A6P5DPG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:LOC109569153
gene id: 9915:LOC109569153
uniprot id: A0A6P5CWA3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MYADM
gene id: 9915:MYADM
uniprot id: A0A6P5DBR3
names: Subcellular Location Annotation
messages: Membrane

9915:P4HA3
gene id: 9915:P4HA3
uniprot id: A0A6P5CXP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

9915:ANO4
gene id: 9915:ANO4
uniprot id: A0A6P5BTZ8
uniprot id: A0A6P5BU07
uniprot id: A0A6P5BU12
uniprot id: A0A6P5BU14
uniprot id: A0A6P5BU19
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:AKAP3
gene id: 9915:AKAP3
uniprot id: A0A6P5BS98
names: Similarity
messages: Belongs to the AKAP110 family.

9915:LOC109567050
gene id: 9915:LOC109567050
uniprot id: A0A6P5CNW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:TAS2R5
gene id: 9915:TAS2R5
uniprot id: A0A6P5BLI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:PLXNA3
gene id: 9915:PLXNA3
uniprot id: A0A6P5BG44
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109554224
gene id: 9915:LOC109554224
uniprot id: A0A6P5BJL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FOXN4
gene id: 9915:FOXN4
uniprot id: A0A6P5D3D6
names: Subcellular Location Annotation
messages: Nucleus

9915:FGF21
gene id: 9915:FGF21
uniprot id: A0A6P5DAY7
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

9915:UBE2K
gene id: 9915:UBE2K
uniprot id: A0A6P5BXX0
uniprot id: A0A6P5BYS4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

9915:MAP1LC3B
gene id: 9915:MAP1LC3B
uniprot id: A0A6P5DBR9
names: Similarity
messages: Belongs to the ATG8 family.

9915:NUP50
gene id: 9915:NUP50
uniprot id: A0A6P5BWQ6
names: Subcellular Location Annotation
messages: nuclear pore complex

9915:CLDN34
gene id: 9915:CLDN34
uniprot id: A0A6P5BEH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

9915:SAMD4A
gene id: 9915:SAMD4A
uniprot id: A0A6P5CF56
uniprot id: A0A6P5CGP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

9915:TMPRSS7
gene id: 9915:TMPRSS7
uniprot id: A0A6P5CBM4
uniprot id: A0A6P5CCJ7
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109570907
gene id: 9915:LOC109570907
uniprot id: A0A6P5D3A6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CNTF
gene id: 9915:CNTF
uniprot id: A0A6P5CY45
uniprot id: A0A6P5D0Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNTF family.
messages: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
messages: Cytoplasm

9915:ANO6
gene id: 9915:ANO6
uniprot id: A0A6P5BG27
uniprot id: A0A6P5BT07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

9915:PPP1R14D
gene id: 9915:PPP1R14D
uniprot id: A0A6P5CEG1
uniprot id: A0A6P5CF49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP1 inhibitor family.
messages: Cytoplasm
messages: Inhibitor of PPP1CA.
messages: Membrane

9915:PRICKLE1
gene id: 9915:PRICKLE1
uniprot id: A0A6P5BDU9
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

9915:IGFBP6
gene id: 9915:IGFBP6
uniprot id: A0A6P5BFJ5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:SNRNP200
gene id: 9915:SNRNP200
uniprot id: A0A6P5CJZ2
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

9915:YWHAG
gene id: 9915:YWHAG
uniprot id: A0A6P5E1Z9
names: Similarity
messages: Belongs to the 14-3-3 family.

9915:PADI2
gene id: 9915:PADI2
uniprot id: A0A6P5DM64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein arginine deiminase family.
messages: Catalyzes the deimination of arginine residues of proteins.
messages: Cytoplasm

9915:DISP3
gene id: 9915:DISP3
uniprot id: A0A6P5D3U8
names: Subcellular Location Annotation
messages: Membrane

9915:CLUH
gene id: 9915:CLUH
uniprot id: A0A6P5DFA7
uniprot id: A0A6P5DFB1
uniprot id: A0A6P5DHQ0
uniprot id: A0A6P5DI89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

9915:CAPN7
gene id: 9915:CAPN7
uniprot id: A0A6P5C2Q0
uniprot id: A0A6P5C423
names: Similarity
messages: Belongs to the peptidase C2 family.

9915:GPX3
gene id: 9915:GPX3
uniprot id: A0A6P5C6R8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:GYS2
gene id: 9915:GYS2
uniprot id: A0A6P5BUV5
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

9915:LOC109562255
gene id: 9915:LOC109562255
uniprot id: A0A6P5C5K0
names: Subcellular Location Annotation
messages: Membrane

9915:CD244
gene id: 9915:CD244
uniprot id: A0A6P5DY26
uniprot id: A0A6P5DY33
names: Subcellular Location Annotation
messages: Membrane

9915:PLA1A
gene id: 9915:PLA1A
uniprot id: A0A6P5DU52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9915:LOC109568300
gene id: 9915:LOC109568300
uniprot id: A0A6P5CSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

9915:BARHL1
gene id: 9915:BARHL1
uniprot id: A0A6P5CGQ9
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109556756
gene id: 9915:LOC109556756
uniprot id: A0A6P5BQ32
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LNPEP
gene id: 9915:LNPEP
uniprot id: A0A6P5C5W0
uniprot id: A0A6P5C796
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Membrane

9915:LOC109561936
gene id: 9915:LOC109561936
uniprot id: A0A6P5C441
uniprot id: A0A6P5C4G0
uniprot id: A0A6P5C5G4
names: Similarity
messages: Belongs to the MHC class I family.

9915:SELENBP1
gene id: 9915:SELENBP1
uniprot id: A0A6P5BL99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Interacts with USP33.
messages: Membrane
messages: Nucleus
messages: cytosol

9915:LANCL1
gene id: 9915:LANCL1
uniprot id: A0A6P5D0S1
names: Similarity
messages: Belongs to the LanC-like protein family.

9915:DSE
gene id: 9915:DSE
uniprot id: A0A6P5CAE4
uniprot id: A0A6P5CAU6
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

9915:CCNF
gene id: 9915:CCNF
uniprot id: A0A6P5E0D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: centriole
messages: perinuclear region

9915:SHMT1
gene id: 9915:SHMT1
uniprot id: A0A6P5DDS9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

9915:LOC109571620
gene id: 9915:LOC109571620
uniprot id: A0A6P5D5Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

9915:LOC109565403
gene id: 9915:LOC109565403
uniprot id: A0A6P5CJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9915:LOC109576625
gene id: 9915:LOC109576625
uniprot id: A0A6P5DSI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SULT6B1
gene id: 9915:SULT6B1
uniprot id: A0A6P5CJ89
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:ATP6V1B1
gene id: 9915:ATP6V1B1
uniprot id: A0A6P5CHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.

9915:LOC109558530
gene id: 9915:LOC109558530
uniprot id: A0A6P5BRZ8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109563258
gene id: 9915:LOC109563258
uniprot id: A0A6P5C9J2
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

9915:CUL4A
gene id: 9915:CUL4A
uniprot id: A0A6P5CPI5
names: Similarity
messages: Belongs to the cullin family.

9915:PAH
gene id: 9915:PAH
uniprot id: A0A6P5BU46
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

9915:ENPEP
gene id: 9915:ENPEP
uniprot id: A0A6P5BX30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.
messages: Membrane
messages: Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.

9915:TM4SF18
gene id: 9915:TM4SF18
uniprot id: A0A6P5BTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

9915:LOC109569425
gene id: 9915:LOC109569425
uniprot id: A0A6P5CZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109564527
gene id: 9915:LOC109564527
uniprot id: A0A6P5CE06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC6A5
gene id: 9915:SLC6A5
uniprot id: A0A6P5AZV5
uniprot id: A0A6P5BBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

9915:PRKAR2B
gene id: 9915:PRKAR2B
uniprot id: A0A6P5BJZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

9915:SORD
gene id: 9915:SORD
uniprot id: A0A6P5CFL2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 1 or 2 Zn(2+) ions per subunit.
messages: Homotetramer.
messages: Mitochondrion membrane
messages: Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is active with D-sorbitol (D-glucitol) leading to the C2-oxidized product D-fructose. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.
messages: flagellum

9915:LOC109561049
gene id: 9915:LOC109561049
uniprot id: A0A6P5C0L4
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109573243
gene id: 9915:LOC109573243
uniprot id: A0A6P5DCI5
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109568372
gene id: 9915:LOC109568372
uniprot id: A0A6P5CTZ6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:DPH2
gene id: 9915:DPH2
uniprot id: A0A6P5B8H5
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

9915:LOC109571669
gene id: 9915:LOC109571669
uniprot id: A0A6P5D7N7
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

9915:PHYHIPL
gene id: 9915:PHYHIPL
uniprot id: A0A6P5ASB7
names: Similarity
messages: Belongs to the PHYHIP family.

9915:LOC109574670
gene id: 9915:LOC109574670
uniprot id: A0A6P5DJ31
names: Subcellular Location Annotation
messages: clathrin-coated pit

9915:PEX16
gene id: 9915:PEX16
uniprot id: A0A6P5CWZ0
uniprot id: A0A6P5CXR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

9915:NLN
gene id: 9915:NLN
uniprot id: A0A6P5DLC3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

9915:LOC109569990
gene id: 9915:LOC109569990
uniprot id: A0A6P5CZE8
uniprot id: A0A6P5D1X7
names: Similarity
messages: Belongs to the MS4A family.

9915:LOC109568986
gene id: 9915:LOC109568986
uniprot id: A0A6P5CYJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109576656
gene id: 9915:LOC109576656
uniprot id: A0A6P5DRK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CLN3
gene id: 9915:CLN3
uniprot id: A0A6P5DZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the battenin family.
messages: Lysosome membrane
messages: Membrane

9915:S100A9
gene id: 9915:S100A9
uniprot id: A0A6P5AVY7
names: Similarity
messages: Belongs to the S-100 family.

9915:TNPO1
gene id: 9915:TNPO1
uniprot id: A0A6P5DKD5
names: Subcellular Location Annotation
messages: Cytoplasm

9915:SASS6
gene id: 9915:SASS6
uniprot id: A0A6P5B1R4
uniprot id: A0A6P5BNP9
names: Subcellular Location Annotation
messages: centrosome

9915:SPHKAP
gene id: 9915:SPHKAP
uniprot id: A0A6P5DPB8
names: Similarity
messages: Belongs to the AKAP110 family.

9915:GRB14
gene id: 9915:GRB14
uniprot id: A0A6P5CNR2
uniprot id: A0A6P5CR24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GRB7/10/14 family.
messages: Cytoplasm

9915:LOC109553337
gene id: 9915:LOC109553337
uniprot id: A0A6P5AWS9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:GRM8
gene id: 9915:GRM8
uniprot id: A0A6P5BC99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

9915:DTX1
gene id: 9915:DTX1
uniprot id: A0A6P5D5X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

9915:SLC9A5
gene id: 9915:SLC9A5
uniprot id: A0A6P5D9I4
uniprot id: A0A6P5DBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Membrane

9915:LOC109567108
gene id: 9915:LOC109567108
uniprot id: A0A6P5CPI8
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569915
gene id: 9915:LOC109569915
uniprot id: A0A6P5D2L1
names: Similarity
messages: Belongs to the globin family.

9915:ANAPC15
gene id: 9915:ANAPC15
uniprot id: A0A6P5CVN5
uniprot id: A0A6P5CWI9
uniprot id: A0A6P5CWR1
uniprot id: A0A6P5CZ31
names: Similarity
messages: Belongs to the APC15 family.

9915:LOC109573194
gene id: 9915:LOC109573194
uniprot id: A0A6P5DCE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

9915:LOC109564205
gene id: 9915:LOC109564205
uniprot id: A0A6P5CCZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PAPOLB
gene id: 9915:PAPOLB
uniprot id: A0A6P5DYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Nucleus

9915:FOPNL
gene id: 9915:FOPNL
uniprot id: A0A6P5E0B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: centriole
messages: cilium basal body

9915:CASP8
gene id: 9915:CASP8
uniprot id: A0A6P5CWZ3
names: Similarity
messages: Belongs to the peptidase C14A family.

9915:LOC109559721
gene id: 9915:LOC109559721
uniprot id: A0A6P5BSF2
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

9915:FLOT1
gene id: 9915:FLOT1
uniprot id: A0A6P5DWS4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Cell membrane
messages: Endosome
messages: Heterooligomeric complex of flotillin-1 and flotillin-2 and caveolin-1 and caveolin-2. Interacts with ECPAS.
messages: Membrane
messages: caveola

9915:IL1B
gene id: 9915:IL1B
uniprot id: A0A6P5CJY3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-1 family.
messages: IL1B production occurs in 2 steps, each being controlled by different stimuli. First, inflammatory signals, such as LPS, stimulate the synthesis and promote the accumulation of cytosolic stores of pro-IL1B (priming). Then additional signals are required for inflammasome assembly, leading to CASP1 activation, pro-IL1B processing and eventually secretion of the active cytokine. IL1B processing and secretion are temporarily associated.
messages: Lysosome
messages: Monomer. In its precursor form, weakly interacts with full-length MEFV; the mature cytokine does not interact at all. Interacts with integrins ITGAV:ITGBV and ITGA5:ITGB1; integrin-binding is required for IL1B signaling. Interacts with cargo receptor TMED10; the interaction is direct and is required for the secretion of IL1B mature form. Interacts with HSP90AB1; the interaction facilitates cargo translocation into the ERGIC. Interacts with HSP90B1; the interaction facilitates cargo translocation into the ERGIC.
messages: Monomer. Interacts with MEFV.
messages: Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
messages: Secreted
messages: cytosol
messages: extracellular exosome

9915:COQ10B
gene id: 9915:COQ10B
uniprot id: A0A6P5CV58
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

9915:OSGEPL1
gene id: 9915:OSGEPL1
uniprot id: A0A6P5CHY5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Monomer.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

9915:LOC109561207
gene id: 9915:LOC109561207
uniprot id: A0A6P5C108
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109573543
gene id: 9915:LOC109573543
uniprot id: A0A6P5DDN3
names: Similarity
messages: Belongs to the KRTAP type 3 family.

9915:GRK6
gene id: 9915:GRK6
uniprot id: A0A6P5C3W9
uniprot id: A0A6P5C3Z1
uniprot id: A0A6P5C574
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.

9915:LCN2
gene id: 9915:LCN2
uniprot id: A0A6P5CH86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

9915:C19H17orf105
gene id: 9915:C19H17orf105
uniprot id: A0A6P5DGV6
names: Similarity
messages: Belongs to the CFAP97 family.

9915:SYT16
gene id: 9915:SYT16
uniprot id: A0A6P5CFV4
names: Similarity
messages: Belongs to the synaptotagmin family.

9915:SCRN3
gene id: 9915:SCRN3
uniprot id: A0A6P5CLW5
names: Similarity
messages: Belongs to the peptidase C69 family. Secernin subfamily.

9915:BSCL2
gene id: 9915:BSCL2
uniprot id: A0A6P5BC66
uniprot id: A0A6P5BC72
uniprot id: A0A6P5BJI8
uniprot id: A0A6P5BJS4
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:MS4A5
gene id: 9915:MS4A5
uniprot id: A0A6P5CWX8
names: Similarity
messages: Belongs to the MS4A family.

9915:SH3PXD2B
gene id: 9915:SH3PXD2B
uniprot id: A0A6P5DMC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

9915:LOC109577042
gene id: 9915:LOC109577042
uniprot id: A0A6P5DSR2
names: Similarity
messages: Belongs to the MHC class II family.

9915:UBL3
gene id: 9915:UBL3
uniprot id: A0A6P5CP50
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:SLC41A2
gene id: 9915:SLC41A2
uniprot id: A0A6P5BU71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

9915:PBX2
gene id: 9915:PBX2
uniprot id: A0A6P5DUJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

9915:TRMT1L
gene id: 9915:TRMT1L
uniprot id: A0A6P5D1S5
uniprot id: A0A6P5D518
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

9915:LOC109557774
gene id: 9915:LOC109557774
uniprot id: A0A6P5BR88
uniprot id: A0A6P5BRC2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9915:LOC109555739
gene id: 9915:LOC109555739
uniprot id: A0A6P5BGN5
names: Subcellular Location Annotation
messages: Nucleus

9915:MYRFL
gene id: 9915:MYRFL
uniprot id: A0A6P5BG83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRF family.
messages: Membrane

9915:LOC109565814
gene id: 9915:LOC109565814
uniprot id: A0A6P5CH80
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SRY
gene id: 9915:SRY
uniprot id: A1XCJ7
uniprot id: Q7JGF7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetylation of Lys-130 contributes to its nuclear localization and enhances its interaction with KPNB1. Deacetylated by HDAC3.
messages: Belongs to the SRY family.
messages: Cytoplasm
messages: Interacts with CALM, EP300, HDAC3, KPNB1, ZNF208 isoform KRAB-O, PARP1, SLC9A3R2 and WT1. The interaction with EP300 modulates its DNA-binding activity. The interaction with KPNB1 is sensitive to dissociation by Ran in the GTP-bound form. Interaction with PARP1 impaired its DNA-binding activity.
messages: Nucleus
messages: Nucleus speckle
messages: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity).
messages: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells. Involved in different aspects of gene regulation including promoter activation or repression. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'. SRY HMG box recognizes DNA by partial intercalation in the minor groove and promotes DNA bending. Also involved in pre-mRNA splicing (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons.

9915:MRPL46
gene id: 9915:MRPL46
uniprot id: A0A6P5DN82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

9915:DYNC2H1
gene id: 9915:DYNC2H1
uniprot id: A0A6P5CZI9
uniprot id: A0A6P5D1D4
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:KCNMB3
gene id: 9915:KCNMB3
uniprot id: A0A6P5B9E1
uniprot id: A0A6P5B9F1
uniprot id: A0A6P5BD71
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KCNMB (TC 8.A.14.1) family.
messages: Interacts with KCNMA1 tetramer. There are probably 4 molecules of KCMNB per KCNMA1 tetramer.
messages: Membrane
messages: N-glycosylated.
messages: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity.

9915:TSPAN11
gene id: 9915:TSPAN11
uniprot id: A0A6P5BVR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

9915:LOC109563776
gene id: 9915:LOC109563776
uniprot id: A0A6P5CAS4
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

9915:LOC109564372
gene id: 9915:LOC109564372
uniprot id: A0A6P5CE96
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

9915:RRP8
gene id: 9915:RRP8
uniprot id: A0A6P5CYW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: Component of the eNoSC complex.
messages: Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and probably acts as a methyltransferase.
messages: nucleolus

9915:FOXA2
gene id: 9915:FOXA2
uniprot id: A0A6P5CVI8
names: Subcellular Location Annotation
messages: Nucleus

9915:CUL7
gene id: 9915:CUL7
uniprot id: A0A6P5DT57
names: Similarity
messages: Belongs to the cullin family.

9915:MYBBP1A
gene id: 9915:MYBBP1A
uniprot id: A0A6P5DIB4
names: Similarity
messages: Belongs to the MYBBP1A family.

9915:LOC109572938
gene id: 9915:LOC109572938
uniprot id: A0A6P5DDX7
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109569283
gene id: 9915:LOC109569283
uniprot id: A0A6P5CZ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MLH1
gene id: 9915:MLH1
uniprot id: A0A6P5DN02
uniprot id: A0A6P5DPE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

9915:RTCB
gene id: 9915:RTCB
uniprot id: A0A6P5BU99
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

9915:BECN1
gene id: 9915:BECN1
uniprot id: A0A6P5DJC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Beclin-1-C 35 kDa localized to mitochondria can promote apoptosis; it induces the mitochondrial translocation of BAX and the release of proapoptotic factors.
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

9915:SNU13
gene id: 9915:SNU13
uniprot id: A0A6P5BWI8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

9915:WASL
gene id: 9915:WASL
uniprot id: A0A6P5B827
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109575609
gene id: 9915:LOC109575609
uniprot id: A0A6P5DQU5
names: Subcellular Location Annotation
messages: Membrane

9915:DNASE1L3
gene id: 9915:DNASE1L3
uniprot id: A0A6P5DU01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNase I family.
messages: Nucleus envelope
messages: Zymogen granule

9915:CACNA1A
gene id: 9915:CACNA1A
uniprot id: A0A6P5C0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

9915:BLOC1S2
gene id: 9915:BLOC1S2
uniprot id: A0A6P5B853
names: Similarity
messages: Belongs to the BLOC1S2 family.

9915:LOC109571843
gene id: 9915:LOC109571843
uniprot id: A0A6P5D6K9
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109554277
gene id: 9915:LOC109554277
uniprot id: A0A6P5BC30
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:INSIG2
gene id: 9915:INSIG2
uniprot id: A0A6P5CUJ7
uniprot id: A0A6P5CUU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

9915:HOXC4
gene id: 9915:HOXC4
uniprot id: A0A6P5BSJ1
uniprot id: A0A6P5BSL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

9915:LOC109565118
gene id: 9915:LOC109565118
uniprot id: A0A6P5CER6
names: Similarity
messages: Belongs to the cytochrome P450 family.

9915:TSR1
gene id: 9915:TSR1
uniprot id: A0A6P5DDY9
uniprot id: A0A6P5DDZ2
uniprot id: A0A6P5DFN3
names: Subcellular Location Annotation
messages: nucleolus

9915:SEMA4G
gene id: 9915:SEMA4G
uniprot id: A0A6P5E0Z1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109558360
gene id: 9915:LOC109558360
uniprot id: A0A6P5BRW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HK1
gene id: 9915:HK1
uniprot id: A0A6P5AS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hexokinase family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: cytosol

9915:FADS3
gene id: 9915:FADS3
uniprot id: A0A6P5B1F9
uniprot id: A0A6P5BDQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Endoplasmic reticulum membrane

9915:SLC30A7
gene id: 9915:SLC30A7
uniprot id: A0A6P5BNM3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Homooligomer.
messages: Membrane
messages: trans-Golgi network membrane

9915:DLST
gene id: 9915:DLST
uniprot id: A0A6P5CIQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

9915:LOC109568899
gene id: 9915:LOC109568899
uniprot id: A0A6P5CYB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:S100A13
gene id: 9915:S100A13
uniprot id: A0A6P5BDU3
names: Similarity
messages: Belongs to the S-100 family.

9915:TYSND1
gene id: 9915:TYSND1
uniprot id: A0A6P5ARL6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

9915:LAMA4
gene id: 9915:LAMA4
uniprot id: A0A6P5CBJ1
uniprot id: A0A6P5CCA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:STAT4
gene id: 9915:STAT4
uniprot id: A0A6P5DQA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

9915:CCNK
gene id: 9915:CCNK
uniprot id: A0A6P5DQ34
names: Similarity
messages: Belongs to the cyclin family.

9915:ARPC3
gene id: 9915:ARPC3
uniprot id: A0A6P5D5J8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

9915:LOC109573495
gene id: 9915:LOC109573495
uniprot id: A0A6P5DDH5
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109577977
gene id: 9915:LOC109577977
uniprot id: A0A6P5E068
names: Similarity
messages: Belongs to the serpin family.

9915:SH3RF3
gene id: 9915:SH3RF3
uniprot id: A0A6P5CJU9
names: Similarity
messages: Belongs to the SH3RF family.

9915:LOC109565849
gene id: 9915:LOC109565849
uniprot id: A0A6P5CJC6
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:S100PBP
gene id: 9915:S100PBP
uniprot id: A0A6P5D9X0
uniprot id: A0A6P5D9Y1
names: Subcellular Location Annotation
messages: Nucleus

9915:RPS23
gene id: 9915:RPS23
uniprot id: A0A6P5C729
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

9915:DNASE2B
gene id: 9915:DNASE2B
uniprot id: A0A6P5B2E5
uniprot id: A0A6P5BNW6
uniprot id: A0A6P5BNY9
names: Similarity
messages: Belongs to the DNase II family.

9915:TAS2R60
gene id: 9915:TAS2R60
uniprot id: A0A6P5BRH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:TMEM94
gene id: 9915:TMEM94
uniprot id: A0A6P5DEJ9
uniprot id: A0A6P5DEK1
uniprot id: A0A6P5DEK5
uniprot id: A0A6P5DG85
uniprot id: A0A6P5DGZ0
uniprot id: A0A6P5DHK2
names: Subcellular Location Annotation
messages: Membrane

9915:GRIN2D
gene id: 9915:GRIN2D
uniprot id: A0A6P5D6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

9915:SYNGR3
gene id: 9915:SYNGR3
uniprot id: A0A6P5DZZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

9915:KCNC3
gene id: 9915:KCNC3
uniprot id: A0A6P5D8G0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109575784
gene id: 9915:LOC109575784
uniprot id: A0A6P5DMM1
names: Subcellular Location Annotation
messages: Membrane

9915:PKP2
gene id: 9915:PKP2
uniprot id: A0A6P5BUK0
uniprot id: A0A6P5BUS0
names: Similarity
messages: Belongs to the beta-catenin family.

9915:CC2D2B
gene id: 9915:CC2D2B
uniprot id: A0A6P5AVZ7
uniprot id: A0A6P5BGI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

9915:LOC109553370
gene id: 9915:LOC109553370
uniprot id: A0A6P5BHK3
names: Similarity
messages: Belongs to the histone H2B family.

9915:TRRAP
gene id: 9915:TRRAP
uniprot id: A0A6P5E0S7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

9915:FAM135B
gene id: 9915:FAM135B
uniprot id: A0A6P5CXV6
names: Similarity
messages: Belongs to the FAM135 family.

9915:RIOK2
gene id: 9915:RIOK2
uniprot id: A0A6P5C5W6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

9915:DOCK6
gene id: 9915:DOCK6
uniprot id: A0A6P5C2G9
names: Similarity
messages: Belongs to the DOCK family.

9915:CPNE2
gene id: 9915:CPNE2
uniprot id: A0A6P5D636
names: Similarity
messages: Belongs to the copine family.

9915:LOC109560951
gene id: 9915:LOC109560951
uniprot id: A0A6P5C046
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ZNF703
gene id: 9915:ZNF703
uniprot id: A0A6P5AQP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

9915:MDM2
gene id: 9915:MDM2
uniprot id: A0A6P5BRY5
names: Subcellular Location Annotation
messages: nucleolus
messages: nucleoplasm

9915:SPAST
gene id: 9915:SPAST
uniprot id: A0A6P5CGE7
names: Similarity
messages: Belongs to the AAA ATPase family.

9915:STC1
gene id: 9915:STC1
uniprot id: A0A6P5C9V2
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

9915:GUCY2F
gene id: 9915:GUCY2F
uniprot id: A0A6P5BLE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane
messages: Photoreceptor outer segment membrane

9915:LOC109571738
gene id: 9915:LOC109571738
uniprot id: A0A6P5D7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

9915:PMEL
gene id: 9915:PMEL
uniprot id: A0A6P5BTU0
names: Similarity
messages: Belongs to the PMEL/NMB family.

9915:SLC9A3R1
gene id: 9915:SLC9A3R1
uniprot id: A0A6P5DIC0
names: Function
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Endomembrane system
messages: Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
messages: filopodium
messages: microvillus
messages: ruffle

9915:LOC109576952
gene id: 9915:LOC109576952
uniprot id: A0A6P5DW33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HMBS
gene id: 9915:HMBS
uniprot id: A0A6P5CYU7
names: Similarity
messages: Belongs to the HMBS family.

9915:OSBPL2
gene id: 9915:OSBPL2
uniprot id: A0A6P5CPL9
names: Similarity
messages: Belongs to the OSBP family.

9915:GSPT2
gene id: 9915:GSPT2
uniprot id: A0A6P5BGA1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

9915:C6H4orf48
gene id: 9915:C6H4orf48
uniprot id: A0A6P5BWJ1
names: Subcellular Location Annotation
messages: Secreted

9915:ARMC9
gene id: 9915:ARMC9
uniprot id: A0A6P5D6X9
uniprot id: A0A6P5D9E4
uniprot id: A0A6P5DAL8
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with TOGARAM1, CCDC66, CEP104, CSPP1 and CEP290.
messages: centriole
messages: cilium
messages: cilium basal body

9915:LOC109564294
gene id: 9915:LOC109564294
uniprot id: A0A6P5CD33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ZDHHC15
gene id: 9915:ZDHHC15
uniprot id: A0A6P5B517
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:LOC109563657
gene id: 9915:LOC109563657
uniprot id: A0A6P5C9X7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:PDS5B
gene id: 9915:PDS5B
uniprot id: A0A6P5CLG6
uniprot id: A0A6P5CNC0
uniprot id: A0A6P5CQ39
names: Similarity
messages: Belongs to the PDS5 family.

9915:LOC109569539
gene id: 9915:LOC109569539
uniprot id: A0A6P5CX34
names: Subcellular Location Annotation
messages: Membrane

9915:TPM3
gene id: 9915:TPM3
uniprot id: A0A6P5AU49
uniprot id: A0A6P5AU58
uniprot id: A0A6P5AUA8
uniprot id: A0A6P5B0F8
uniprot id: A0A6P5B0I1
uniprot id: A0A6P5BCH6
uniprot id: A0A6P5BJP7
uniprot id: A0A6P5BJQ3
uniprot id: A0A6P5BJQ9
uniprot id: A0A6P5BJT8
uniprot id: A0A6P5BK05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9915:TXN
gene id: 9915:TXN
uniprot id: A0A6P5C9Z0
names: Similarity
messages: Belongs to the thioredoxin family.

9915:LOC109563967
gene id: 9915:LOC109563967
uniprot id: A0A6P5CB73
uniprot id: A0A6P5CCF8
uniprot id: A0A6P5CD56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily.
messages: Cytoplasm

9915:HNRNPH1
gene id: 9915:HNRNPH1
uniprot id: A0A6P5C112
uniprot id: A0A6P5C229
names: Subcellular Location Annotation
messages: nucleoplasm

9915:LOC109576409
gene id: 9915:LOC109576409
uniprot id: A0A6P5DRU5
uniprot id: A0A6P5DU39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Mitochondrion inner membrane

9915:JPH4
gene id: 9915:JPH4
uniprot id: A0A6P5CDG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

9915:EIF3E
gene id: 9915:EIF3E
uniprot id: A0A6P5CUX2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit E family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Interacts with COPS3, COPS6, COPS7 (COPS7A or COPS7B), EIF4G1, EPAS1, MCM7, NCBP1, PSMC6, TRIM27 and UPF2.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
messages: Cytoplasm
messages: Nucleus
messages: PML body
messages: Phosphorylated upon DNA damage, probably by ATM or ATR.

9915:LOC109557356
gene id: 9915:LOC109557356
uniprot id: A0A6P5BJW9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M16 family.
messages: Heterodimer of PMPCA (alpha) and PMPCB (beta) subunits, forming the mitochondrial processing protease (MPP) in which PMPCA is involved in substrate recognition and binding and PMPCB is the catalytic subunit.
messages: Mitochondrion matrix

9915:TLX1
gene id: 9915:TLX1
uniprot id: A0A6P5B8C7
names: Subcellular Location Annotation
messages: Nucleus

9915:SRFBP1
gene id: 9915:SRFBP1
uniprot id: A0A6P5C3S2
names: Function
names: Subunit
messages: Interacts with SRF. Forms complexes with SRF and SRF cofactors ARID2, MYOCD and NKX2-5. Interacts with the N-terminus of SLC2A4.
messages: May be involved in regulating transcriptional activation of cardiac genes during the aging process. May play a role in biosynthesis and/or processing of SLC2A4 in adipose cells.

9915:MTX1
gene id: 9915:MTX1
uniprot id: A0A6P5BI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

9915:METAP2
gene id: 9915:METAP2
uniprot id: A0A6P5BSI0
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

9915:ENSA
gene id: 9915:ENSA
uniprot id: A0A6P5B4H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endosulfine family.
messages: Cytoplasm
messages: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.

9915:XIRP1
gene id: 9915:XIRP1
uniprot id: A0A6P5DNR9
uniprot id: A0A6P5DPJ5
names: Domain
names: Function
names: Similarity
messages: Belongs to the Xin family.
messages: Protects actin filaments from depolymerization.
messages: Xin repeats bind F-actin.

9915:LOC109567625
gene id: 9915:LOC109567625
uniprot id: A0A6P5CQ63
names: Similarity
messages: Belongs to the histone H2B family.

9915:XRN1
gene id: 9915:XRN1
uniprot id: A0A6P5BV00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm

9915:PPP4R3B
gene id: 9915:PPP4R3B
uniprot id: A0A6P5CIA8
uniprot id: A0A6P5CJ81
names: Similarity
messages: Belongs to the SMEK family.

9915:LOC109563616
gene id: 9915:LOC109563616
uniprot id: A0A6P5CAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCRIP family.
messages: Nucleus
messages: Stress granule

9915:PPP2R3C
gene id: 9915:PPP2R3C
uniprot id: A0A6P5DLW8
uniprot id: A0A6P5DLX2
uniprot id: A0A6P5DMM2
uniprot id: A0A6P5DPL8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:IL7
gene id: 9915:IL7
uniprot id: A0A6P5CVH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IL-7/IL-9 family.
messages: Hematopoietic cytokine that plays an essential role in the development, expansion, and survival of naive and memory T-cells and B-cells thereby regulating the number of mature lymphocytes and maintaining lymphoid homeostasis.
messages: Interacts with IL7R and CSF2RG.
messages: Secreted

9915:NDUFB9
gene id: 9915:NDUFB9
uniprot id: A0A6P5CTG4
uniprot id: A0A6P5CUW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:GDPD5
gene id: 9915:GDPD5
uniprot id: A0A6P5D1A3
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9915:LETM1
gene id: 9915:LETM1
uniprot id: A0A6P5BZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

9915:TRIM72
gene id: 9915:TRIM72
uniprot id: A0A6P5E235
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle membrane
messages: sarcolemma

9915:LOC109560843
gene id: 9915:LOC109560843
uniprot id: A0A6P5C072
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PRKG2
gene id: 9915:PRKG2
uniprot id: A0A6P5BZV2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

9915:CECR1
gene id: 9915:CECR1
uniprot id: A0A6P5BEF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

9915:LOC109564260
gene id: 9915:LOC109564260
uniprot id: A0A6P5CCD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:ENDOU
gene id: 9915:ENDOU
uniprot id: A0A6P5BG03
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

9915:DCTN1
gene id: 9915:DCTN1
uniprot id: A0A6P5CHJ8
uniprot id: A0A6P5CIH3
uniprot id: A0A6P5CIZ6
uniprot id: A0A6P5CJ00
uniprot id: A0A6P5CJN9
uniprot id: A0A6P5CJP7
uniprot id: A0A6P5CKL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin 150 kDa subunit family.
messages: cell cortex
messages: cytoskeleton

9915:GABRA6
gene id: 9915:GABRA6
uniprot id: A0A6P5C176
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:SMARCA1
gene id: 9915:SMARCA1
uniprot id: A0A6P5BLZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

9915:EPHB2
gene id: 9915:EPHB2
uniprot id: A0A6P5DIR6
uniprot id: A0A6P5DIS8
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555635
gene id: 9915:LOC109555635
uniprot id: A0A6P5BMZ9
names: Subcellular Location Annotation
messages: Nucleus

9915:SPICE1
gene id: 9915:SPICE1
uniprot id: A0A6P5DHM6
uniprot id: A0A6P5DI88
uniprot id: A0A6P5DII9
uniprot id: A0A6P5DKC9
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with CEP120.
messages: centriole
messages: spindle

9915:GGA2
gene id: 9915:GGA2
uniprot id: A0A6P5E052
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

9915:LOC109557935
gene id: 9915:LOC109557935
uniprot id: A0A6P5BDA9
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

9915:SMARCA5
gene id: 9915:SMARCA5
uniprot id: A0A6P5D5M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

9915:TFAP2C
gene id: 9915:TFAP2C
uniprot id: A0A6P5CR44
names: Similarity
messages: Belongs to the AP-2 family.

9915:MB21D2
gene id: 9915:MB21D2
uniprot id: A0A6P5B9S4
uniprot id: A0A6P5BPY6
names: Similarity
messages: Belongs to the mab-21 family.

9915:LRP2
gene id: 9915:LRP2
uniprot id: A0A6P5CMR5
uniprot id: A0A6P5CNB0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDLR family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:ZADH2
gene id: 9915:ZADH2
uniprot id: A0A6P5DZI7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

9915:SLC4A1
gene id: 9915:SLC4A1
uniprot id: A0A6P5DDH7
uniprot id: A0A6P5DF87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Cell membrane
messages: Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine.
messages: Membrane

9915:MYF6
gene id: 9915:MYF6
uniprot id: A0A6P5BCH3
names: Subcellular Location Annotation
messages: Nucleus

9915:CSF1
gene id: 9915:CSF1
uniprot id: A0A6P5BNK4
names: Function
names: Subunit
messages: Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance.
messages: Homodimer or heterodimer; disulfide-linked. Interacts with CSF1R.

9915:LOC109558748
gene id: 9915:LOC109558748
uniprot id: A0A6P5BBL0
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:DKK4
gene id: 9915:DKK4
uniprot id: A0A6P5AWU7
names: Similarity
messages: Belongs to the dickkopf family.

9915:HOOK2
gene id: 9915:HOOK2
uniprot id: A0A6P5C1X3
uniprot id: A0A6P5C2A3
uniprot id: A0A6P5C2C2
uniprot id: A0A6P5C337
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

9915:DUSP7
gene id: 9915:DUSP7
uniprot id: A0A6P5DRE9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9915:CDX1
gene id: 9915:CDX1
uniprot id: A0A6P5C161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

9915:SULT1B1
gene id: 9915:SULT1B1
uniprot id: A0A6P5BYN7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:PTPRN
gene id: 9915:PTPRN
uniprot id: A0A6P5D4V7
uniprot id: A0A6P5D4W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily.
messages: Membrane
messages: secretory vesicle membrane

9915:AK6
gene id: 9915:AK6
uniprot id: A0A6P5DJZ4
uniprot id: A0A6P5DN25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

9915:NDUFB2
gene id: 9915:NDUFB2
uniprot id: A0A6P5BCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB2 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

9915:KLHDC3
gene id: 9915:KLHDC3
uniprot id: A0A6P5DRQ6
uniprot id: A0A6P5DT61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

9915:FXYD6
gene id: 9915:FXYD6
uniprot id: A0A6P5CZ74
names: Similarity
messages: Belongs to the FXYD family.

9915:PLPPR5
gene id: 9915:PLPPR5
uniprot id: A0A6P5B6S7
uniprot id: A0A6P5BNN8
uniprot id: A0A6P5BNQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

9915:LIMK2
gene id: 9915:LIMK2
uniprot id: A0A6P5D3W6
uniprot id: A0A6P5D4E2
uniprot id: A0A6P5D542
uniprot id: A0A6P5D690
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

9915:CHST4
gene id: 9915:CHST4
uniprot id: A0A6P5D9K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9915:PDIA6
gene id: 9915:PDIA6
uniprot id: A0A6P5CJK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

9915:GPR137B
gene id: 9915:GPR137B
uniprot id: A0A6P5BIW2
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

9915:TPT1
gene id: 9915:TPT1
uniprot id: A0A6P5CNH7
names: Similarity
messages: Belongs to the TCTP family.

9915:CD3E
gene id: 9915:CD3E
uniprot id: A0A6P5D2R1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:RECQL5
gene id: 9915:RECQL5
uniprot id: A0A6P5DF65
uniprot id: A0A6P5DGT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RecQ subfamily.
messages: Nucleus

9915:LOC109560173
gene id: 9915:LOC109560173
uniprot id: A0A6P5BXC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

9915:MPHOSPH10
gene id: 9915:MPHOSPH10
uniprot id: A0A6P5DQF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

9915:SPIRE1
gene id: 9915:SPIRE1
uniprot id: A0A6P5DVC7
uniprot id: A0A6P5DZC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

9915:EIF3M
gene id: 9915:EIF3M
uniprot id: A0A6P5CYA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Belongs to the eIF-3 subunit M family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: Cytoplasm

9915:GOLPH3L
gene id: 9915:GOLPH3L
uniprot id: A0A6P5B4D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

9915:KEG07 p03
gene id: 9915:KEG07_p03
uniprot id: A0A343AY74
uniprot id: Q576B4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of respiratory chain NADH dehydrogenase (Complex I) which is composed of 45 different subunits.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

9915:KCNK18
gene id: 9915:KCNK18
uniprot id: A0A6P5E435
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9915:SNAP23
gene id: 9915:SNAP23
uniprot id: A0A6P5CDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

9915:LGR4
gene id: 9915:LGR4
uniprot id: A0A6P5CYC7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:SEC24C
gene id: 9915:SEC24C
uniprot id: A0A6P5ARU9
uniprot id: A0A6P5BAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9915:EFEMP2
gene id: 9915:EFEMP2
uniprot id: A0A6P5BD24
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:WARS
gene id: 9915:WARS
uniprot id: A0A6P5DM73
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

9915:MAP1LC3C
gene id: 9915:MAP1LC3C
uniprot id: A0A6P5CZV5
names: Similarity
messages: Belongs to the ATG8 family.

9915:LOC109563542
gene id: 9915:LOC109563542
uniprot id: A0A6P5C9S1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:SGIP1
gene id: 9915:SGIP1
uniprot id: A0A6P5B2S1
uniprot id: A0A6P5BHS9
names: Function
names: Subcellular Location Annotation
messages: May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
messages: clathrin-coated pit

9915:CD27
gene id: 9915:CD27
uniprot id: A0A6P5BVE8
uniprot id: A0A6P5BVF1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:PHB2
gene id: 9915:PHB2
uniprot id: A0A6P5BEZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

9915:MYBL1
gene id: 9915:MYBL1
uniprot id: A0A6P5CVB7
uniprot id: A0A6P5CWX1
names: Subcellular Location Annotation
messages: Nucleus

9915:PSMA7
gene id: 9915:PSMA7
uniprot id: A0A6P5CQ61
uniprot id: A0A6P5CQY4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

9915:SEC22B
gene id: 9915:SEC22B
uniprot id: A0A6P5B600
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

9915:NDUFS7
gene id: 9915:NDUFS7
uniprot id: A0A6P5C5P2
names: Similarity
messages: Belongs to the complex I 20 kDa subunit family.

9915:LOC109569170
gene id: 9915:LOC109569170
uniprot id: A0A6P5CVH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:JMJD1C
gene id: 9915:JMJD1C
uniprot id: A0A6P5AR79
uniprot id: A0A6P5BHV4
uniprot id: A0A6P5BHV7
uniprot id: A0A6P5BI75
names: Subcellular Location Annotation
messages: Nucleus

9915:CCL19
gene id: 9915:CCL19
uniprot id: A0A6P5C8M0
uniprot id: A0A6P5C8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:PPIL6
gene id: 9915:PPIL6
uniprot id: A0A6P5CAM0
uniprot id: A0A6P5CBB6
uniprot id: A0A6P5CBC0
uniprot id: A0A6P5CBQ4
uniprot id: A0A6P5CCE8
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9915:LOC109569513
gene id: 9915:LOC109569513
uniprot id: A0A6P5CZB9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CHST13
gene id: 9915:CHST13
uniprot id: A0A6P5B5B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:CDC26
gene id: 9915:CDC26
uniprot id: A0A6P5C9D1
names: Function
names: Similarity
messages: Belongs to the CDC26 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.

9915:HMGB2
gene id: 9915:HMGB2
uniprot id: A0A6P5C894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

9915:AURKB
gene id: 9915:AURKB
uniprot id: A0A6P5DIY0
uniprot id: A0A6P5DLC9
uniprot id: A0A6P5DLX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centromere

9915:LOC109576813
gene id: 9915:LOC109576813
uniprot id: A0A6P5DSZ1
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MIF
gene id: 9915:MIF
uniprot id: A0A6P5D3I7
names: Similarity
messages: Belongs to the MIF family.

9915:LOC109579092
gene id: 9915:LOC109579092
uniprot id: A0A6P5E0N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

9915:GPR61
gene id: 9915:GPR61
uniprot id: A0A6P5BH59
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:KIDINS220
gene id: 9915:KIDINS220
uniprot id: A0A6P5CKV1
names: Function
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with pi-bodies suggests a participation in the primary piRNAs metabolic process. Required prior to the pachytene stage to facilitate the production of multiple types of piRNAs, including those associated with repeats involved in the regulation of retrotransposons. May act by mediating protein-protein interactions during germ cell maturation.

9915:FMNL1
gene id: 9915:FMNL1
uniprot id: A0A6P5DKW7
names: Similarity
messages: Belongs to the formin homology family.

9915:IL2RA
gene id: 9915:IL2RA
uniprot id: A0A6P5CTU9
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

9915:LOC109568243
gene id: 9915:LOC109568243
uniprot id: A0A6P5CTI9
names: Subcellular Location Annotation
messages: Membrane

9915:KCNJ3
gene id: 9915:KCNJ3
uniprot id: A0A6P5CSD0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

9915:LOC109575829
gene id: 9915:LOC109575829
uniprot id: A0A6P5DP41
names: Similarity
messages: Belongs to the villin/gelsolin family.

9915:LOC109560516
gene id: 9915:LOC109560516
uniprot id: A0A6P5BYK0
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

9915:MSH4
gene id: 9915:MSH4
uniprot id: A0A6P5BP10
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

9915:LOC109573439
gene id: 9915:LOC109573439
uniprot id: A0A6P5DFT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

9915:BTG3
gene id: 9915:BTG3
uniprot id: A0A6P5BWH7
names: Similarity
messages: Belongs to the BTG family.

9915:LOC109562273
gene id: 9915:LOC109562273
uniprot id: A0A6P5C5N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM163A
gene id: 9915:FAM163A
uniprot id: A0A6P5D2N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

9915:LOC109564516
gene id: 9915:LOC109564516
uniprot id: A0A6P5CCU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LONP2
gene id: 9915:LONP2
uniprot id: A0A6P5D9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta-oxidation through degradation of the self-processed forms of TYSND1.
messages: Belongs to the peptidase S16 family.
messages: Interacts with PEX5. Interacts with TYSND1.
messages: Peroxisome matrix

9915:NCOA3
gene id: 9915:NCOA3
uniprot id: A0A6P5CPV2
uniprot id: A0A6P5CQY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

9915:NR2C1
gene id: 9915:NR2C1
uniprot id: A0A6P5BCM9
uniprot id: A0A6P5BF86
uniprot id: A0A6P5BMV9
uniprot id: A0A6P5BSH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

9915:TTC21B
gene id: 9915:TTC21B
uniprot id: A0A6P5CP21
names: Similarity
messages: Belongs to the TTC21 family.

9915:LOC109557787
gene id: 9915:LOC109557787
uniprot id: A0A6P5BL25
uniprot id: A0A6P5BRA2
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

9915:PAPSS2
gene id: 9915:PAPSS2
uniprot id: A0A6P5E041
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

9915:IPPK
gene id: 9915:IPPK
uniprot id: A0A6P5C6D9
names: Domain
names: Function
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

9915:SMS
gene id: 9915:SMS
uniprot id: A0A6P5B299
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

9915:EXOC3L2
gene id: 9915:EXOC3L2
uniprot id: A0A6P5DE14
names: Similarity
messages: Belongs to the SEC6 family.

9915:LOC109569195
gene id: 9915:LOC109569195
uniprot id: A0A6P5CYZ9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

9915:ATG5
gene id: 9915:ATG5
uniprot id: A0A6P5CAQ6
uniprot id: A0A6P5CAR1
uniprot id: A0A6P5CBF3
uniprot id: A0A6P5CBG1
uniprot id: A0A6P5CBW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

9915:NDUFAF7
gene id: 9915:NDUFAF7
uniprot id: A0A6P5CKZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

9915:NTMT1
gene id: 9915:NTMT1
uniprot id: A0A6P5CKC6
uniprot id: A0A6P5CNT5
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9915:SLC26A8
gene id: 9915:SLC26A8
uniprot id: A0A6P5DS85
uniprot id: A0A6P5DSL2
uniprot id: A0A6P5DTM7
uniprot id: A0A6P5DW45
uniprot id: A0A6P5DWH6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:MAP7D1
gene id: 9915:MAP7D1
uniprot id: A0A6P5B4H5
uniprot id: A0A6P5B951
uniprot id: A0A6P5BIR1
uniprot id: A0A6P5BPL7
uniprot id: A0A6P5BPP7
uniprot id: A0A6P5BPP9
names: Similarity
messages: Belongs to the MAP7 family.

9915:LOC109561033
gene id: 9915:LOC109561033
uniprot id: A0A6P5C0A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SCN1B
gene id: 9915:SCN1B
uniprot id: A0A6P5DCB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel auxiliary subunit SCN1B (TC 8.A.17) family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon

9915:DDOST
gene id: 9915:DDOST
uniprot id: A0A6P5DHW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

9915:OLFML2A
gene id: 9915:OLFML2A
uniprot id: A0A6P5CJV9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:MRPL33
gene id: 9915:MRPL33
uniprot id: A0A6P5CK86
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

9915:LOC109559173
gene id: 9915:LOC109559173
uniprot id: A0A6P5BDQ4
uniprot id: A0A6P5BSW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

9915:EHD1
gene id: 9915:EHD1
uniprot id: A0A6P5BK14
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

9915:TICAM1
gene id: 9915:TICAM1
uniprot id: A0A6P5C2X4
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Homodimer. Found in a multi-helicase-TICAM1 complex at least composed of DHX36, DDX1, DDX21 and TICAM1.
messages: Involved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively. Phosphorylation by TBK1 on the pLxIS motif leads to recruitment and subsequent activation of the transcription factor IRF3 to induce expression of type I interferon and exert a potent immunity against invading pathogens. Component of a multi-helicase-TICAM1 complex that acts as a cytoplasmic sensor of viral double-stranded RNA (dsRNA) and plays a role in the activation of a cascade of antiviral responses including the induction of pro-inflammatory cytokines.
messages: Mitochondrion
messages: The N-terminal region is essential for activation of the IFNB promoter activity.
messages: autophagosome
messages: cytosol

9915:LOC109569945
gene id: 9915:LOC109569945
uniprot id: A0A6P5D096
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

9915:LOC109557966
gene id: 9915:LOC109557966
uniprot id: A0A6P5BLC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:CHMP4B
gene id: 9915:CHMP4B
uniprot id: A0A6P5CRU7
names: Similarity
messages: Belongs to the SNF7 family.

9915:GNA15
gene id: 9915:GNA15
uniprot id: A0A6P5C3G7
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

9915:LOC109564512
gene id: 9915:LOC109564512
uniprot id: A0A6P5CCH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:RBL1
gene id: 9915:RBL1
uniprot id: A0A6P5CPE1
uniprot id: A0A6P5CQH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

9915:LOC109569889
gene id: 9915:LOC109569889
uniprot id: A0A6P5D034
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

9915:LOC109577132
gene id: 9915:LOC109577132
uniprot id: A0A6P5DWN7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:DPF3
gene id: 9915:DPF3
uniprot id: A0A6P5CGX9
uniprot id: A0A6P5CHB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the requiem/DPF family.
messages: Nucleus

9915:CTSC
gene id: 9915:CTSC
uniprot id: A0A6P5AU84
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Lysosome
messages: Tetramer of heterotrimers consisting of exclusion domain, heavy- and light chains.

9915:SPR
gene id: 9915:SPR
uniprot id: A0A6P5CJ53
names: Similarity
messages: Belongs to the sepiapterin reductase family.

9915:TLR1
gene id: 9915:TLR1
uniprot id: A0A6P5BXU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane
messages: Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides.

9915:NFIC
gene id: 9915:NFIC
uniprot id: A0A6P5C372
uniprot id: A0A6P5C3B6
uniprot id: A0A6P5C3G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

9915:LOC109556092
gene id: 9915:LOC109556092
uniprot id: A0A6P5BHI0
uniprot id: A0A6P5BNT7
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

9915:CDK5R2
gene id: 9915:CDK5R2
uniprot id: A0A6P5D6I3
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

9915:SEC11C
gene id: 9915:SEC11C
uniprot id: A0A6P5DZF6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:RPS13
gene id: 9915:RPS13
uniprot id: A0A6P5CZP8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

9915:LEPROT
gene id: 9915:LEPROT
uniprot id: A0A6P5B2T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

9915:SLC47A1
gene id: 9915:SLC47A1
uniprot id: A0A6P5DG28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

9915:DGKE
gene id: 9915:DGKE
uniprot id: A0A6P5DFE2
uniprot id: A0A6P5DIC5
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

9915:ROMO1
gene id: 9915:ROMO1
uniprot id: A0A6P5CPA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR2 family.
messages: Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.
messages: Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation.
messages: Mitochondrion inner membrane

9915:DSC3
gene id: 9915:DSC3
uniprot id: A0A6P5DW05
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

9915:BLCAP
gene id: 9915:BLCAP
uniprot id: A0A6P5CT01
names: Similarity
messages: Belongs to the BLCAP family.

9915:UNC5D
gene id: 9915:UNC5D
uniprot id: A0A6P5BHJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

9915:DNAH12
gene id: 9915:DNAH12
uniprot id: A0A6P5DNP9
names: Similarity
messages: Belongs to the dynein heavy chain family.

9915:LOC109560563
gene id: 9915:LOC109560563
uniprot id: A0A6P5BYS9
uniprot id: A0A6P5BZ68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

9915:LOC109559898
gene id: 9915:LOC109559898
uniprot id: A0A6P5BW66
uniprot id: A0A6P5BW69
uniprot id: A0A6P5BWQ1
names: Similarity
messages: Belongs to the PROTOR family.

9915:PLOD2
gene id: 9915:PLOD2
uniprot id: A0A6P5BU89
uniprot id: A0A6P5BUE3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

9915:PURA
gene id: 9915:PURA
uniprot id: A0A6P5C4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PUR DNA-binding protein family.
messages: Nucleus

9915:LOC109577754
gene id: 9915:LOC109577754
uniprot id: A0A6P5DUZ0
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109572252
gene id: 9915:LOC109572252
uniprot id: A0A6P5DAG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

9915:PTH2R
gene id: 9915:PTH2R
uniprot id: A0A6P5D3Y7
names: Subcellular Location Annotation
messages: Membrane

9915:EEF1G
gene id: 9915:EEF1G
uniprot id: A0A6P5AUB1
names: Function
names: Subunit
messages: EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
messages: Probably plays a role in anchoring the complex to other cellular components.

9915:SLC17A8
gene id: 9915:SLC17A8
uniprot id: A0A6P5BU29
names: Subcellular Location Annotation
messages: Membrane

9915:LSM3
gene id: 9915:LSM3
uniprot id: A0A6P5DQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

9915:PAF1
gene id: 9915:PAF1
uniprot id: A0A6P5DA12
names: Similarity
messages: Belongs to the PAF1 family.

9915:LOC109566513
gene id: 9915:LOC109566513
uniprot id: A0A6P5CMM3
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

9915:GDPD1
gene id: 9915:GDPD1
uniprot id: A0A6P5DJG2
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

9915:LOC109555628
gene id: 9915:LOC109555628
uniprot id: A0A6P5B008
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor.
messages: Nucleus

9915:LOC109571690
gene id: 9915:LOC109571690
uniprot id: A0A6P5D9Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the secretoglobin family.
messages: Secreted

9915:LCTL
gene id: 9915:LCTL
uniprot id: A0A6P5CDF6
names: Similarity
messages: Belongs to the glycosyl hydrolase 1 family.

9915:ING2
gene id: 9915:ING2
uniprot id: A0A6P5BHZ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9915:TTC39B
gene id: 9915:TTC39B
uniprot id: A0A6P5C758
names: Similarity
messages: Belongs to the TTC39 family.

9915:MANEA
gene id: 9915:MANEA
uniprot id: A0A6P5CAG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109575587
gene id: 9915:LOC109575587
uniprot id: A0A6P5DML4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

9915:ARHGEF3
gene id: 9915:ARHGEF3
uniprot id: A0A6P5DPE4
uniprot id: A0A6P5DQ02
uniprot id: A0A6P5DT67
uniprot id: A0A6P5DTH6
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

9915:SEPT12
gene id: 9915:SEPT12
uniprot id: A0A6P5DZ52
uniprot id: A0A6P5DZA5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cytoplasm
messages: Filament-forming cytoskeletal GTPase.
messages: Septins polymerize into heterooligomeric protein complexes that form filaments.

9915:DMRTB1
gene id: 9915:DMRTB1
uniprot id: A0A6P5BQ30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

9915:DLX6
gene id: 9915:DLX6
uniprot id: A0A6P5BRT0
names: Subcellular Location Annotation
messages: Nucleus

9915:FOXI1
gene id: 9915:FOXI1
uniprot id: A0A6P5DM03
names: Subcellular Location Annotation
messages: Nucleus

9915:ST6GAL1
gene id: 9915:ST6GAL1
uniprot id: A0A6P5B611
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

9915:NCEH1
gene id: 9915:NCEH1
uniprot id: A0A6P5B9P2
uniprot id: A0A6P5BLD0
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

9915:PLLP
gene id: 9915:PLLP
uniprot id: A0A6P5D9W4
names: Subcellular Location Annotation
messages: Membrane

9915:TJP2
gene id: 9915:TJP2
uniprot id: A0A6P5C7N9
uniprot id: A0A6P5C7Q1
uniprot id: A0A6P5C811
uniprot id: A0A6P5C8X8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

9915:ACTR3
gene id: 9915:ACTR3
uniprot id: A0A6P5CVR6
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

9915:LOC109555256
gene id: 9915:LOC109555256
uniprot id: A0A6P5AXS6
uniprot id: A0A6P5BLZ3
uniprot id: A0A6P5BM15
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:EIF3B
gene id: 9915:EIF3B
uniprot id: A0A6P5DWN5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3. Also interacts with UPF2. Interacts with METTL3.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.
messages: The RRM domain mediates interaction with EIF3J.

9915:LOC109560921
gene id: 9915:LOC109560921
uniprot id: A0A6P5C026
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109568313
gene id: 9915:LOC109568313
uniprot id: A0A6P5CU06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

9915:CELSR3
gene id: 9915:CELSR3
uniprot id: A0A6P5DU43
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Receptor that may have an important role in cell/cell signaling during nervous system formation.

9915:ESCO1
gene id: 9915:ESCO1
uniprot id: A0A6P5DZ49
names: Subcellular Location Annotation
messages: Nucleus

9915:CALCR
gene id: 9915:CALCR
uniprot id: A0A6P5BRS2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

9915:PTCH1
gene id: 9915:PTCH1
uniprot id: A0A6P5CAD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

9915:GATSL2
gene id: 9915:GATSL2
uniprot id: A0A6P5DXD2
names: Similarity
messages: Belongs to the GATS family.

9915:GSG1
gene id: 9915:GSG1
uniprot id: A0A6P5BV15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

9915:CMTM3
gene id: 9915:CMTM3
uniprot id: A0A6P5DBJ1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109561032
gene id: 9915:LOC109561032
uniprot id: A0A6P5C0J8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TTC25
gene id: 9915:TTC25
uniprot id: A0A6P5DIL2
names: Subcellular Location Annotation
messages: cilium axoneme

9915:LOC109565633
gene id: 9915:LOC109565633
uniprot id: A0A6P5CGM9
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558731
gene id: 9915:LOC109558731
uniprot id: A0A6P5BEL3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CEP63
gene id: 9915:CEP63
uniprot id: A0A6P5BWP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: centriolar satellite

9915:HDAC4
gene id: 9915:HDAC4
uniprot id: A0A6P5BQ86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

9915:MCU
gene id: 9915:MCU
uniprot id: A0A6P5BIJ1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCU (TC 1.A.77) family.
messages: Forms a well-packed pentamer with an overall cylindrical shape. The inner core of the pentamer is formed with the second transmembrane region and the second coiled-coil region: while the transmembrane regions pack into a five-helix bundle having a largely polar pore across the membrane, the coiled-coil outside the membrane forms a pentamer with a hydrophobic core. The inner core is wrapped by the first transmembrane region through contacts between the first and the second transmembrane regions. The second transmembrane is followed by the inner juxtamembrane region (IJMH) that orients at a wide angle relative to the second transmembrane. The two core domains are held together on the periphery by the outer juxtamembrane helix (OJMH).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrial inner membrane calcium uniporter that mediates calcium uptake into mitochondria. Constitutes a pore-forming and calcium-conducting subunit. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
messages: Mitochondrion inner membrane

9915:VIPR2
gene id: 9915:VIPR2
uniprot id: A0A6P5BLF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

9915:RPL36A
gene id: 9915:RPL36A
uniprot id: A0A6P5BG78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

9915:RTEL1
gene id: 9915:RTEL1
uniprot id: A0A6P5CNB9
uniprot id: A0A6P5CQR0
uniprot id: A0A6P5CRU0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Interacts with TERF1. Interacts (via PIP-box) with PCNA; the interaction is direct and essential for suppressing telomere fragility. Interacts with MMS19; the interaction mediates the association of RTEL1 with the cytosolic iron-sulfur protein assembly (CIA) complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:LOC109564594
gene id: 9915:LOC109564594
uniprot id: A0A6P5CEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SESN3
gene id: 9915:SESN3
uniprot id: A0A6P5CXV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

9915:LOC109558380
gene id: 9915:LOC109558380
uniprot id: A0A6P5BE55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:KYAT3
gene id: 9915:KYAT3
uniprot id: A0A6P5B268
uniprot id: A0A6P5B743
uniprot id: A0A6P5BNW3
names: Subunit
messages: Homodimer.

9915:ANXA10
gene id: 9915:ANXA10
uniprot id: A0A6P5C6H0
names: Similarity
messages: Belongs to the annexin family.

9915:DDX18
gene id: 9915:DDX18
uniprot id: A0A6P5CVW2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

9915:P3H3
gene id: 9915:P3H3
uniprot id: A0A6P5BC97
names: Similarity
messages: Belongs to the leprecan family.

9915:FFAR1
gene id: 9915:FFAR1
uniprot id: A0A6P5D8V8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:HACL1
gene id: 9915:HACL1
uniprot id: A0A6P5C3A7
names: Similarity
messages: Belongs to the TPP enzyme family.

9915:PPME1
gene id: 9915:PPME1
uniprot id: A0A6P5CWA4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily.
messages: Binds PPP2CA and PPP2CB.
messages: Demethylates proteins that have been reversibly carboxymethylated. Demethylates PPP2CB (in vitro) and PPP2CA. Binding to PPP2CA displaces the manganese ion and inactivates the enzyme.

9915:PNRC2
gene id: 9915:PNRC2
uniprot id: A0A6P5DHU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNRC family. PNRC2 subfamily.
messages: Nucleus
messages: P-body

9915:LOC109565925
gene id: 9915:LOC109565925
uniprot id: A0A6P5CJ09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GREB1
gene id: 9915:GREB1
uniprot id: A0A6P5CKR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

9915:PHOSPHO2
gene id: 9915:PHOSPHO2
uniprot id: A0A6P5CLB2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

9915:WDR48
gene id: 9915:WDR48
uniprot id: A0A6P5DS17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

9915:LOC109555115
gene id: 9915:LOC109555115
uniprot id: A0A6P5B2T3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ING4
gene id: 9915:ING4
uniprot id: A0A6P5BCF0
uniprot id: A0A6P5BSE7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

9915:GC
gene id: 9915:GC
uniprot id: A0A6P5BX23
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

9915:REM1
gene id: 9915:REM1
uniprot id: A0A6P5CPY9
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

9915:LPIN1
gene id: 9915:LPIN1
uniprot id: A0A6P5CKR4
uniprot id: A0A6P5CLZ5
uniprot id: A0A6P5CMW1
names: Similarity
messages: Belongs to the lipin family.

9915:LOC109570176
gene id: 9915:LOC109570176
uniprot id: A0A6P5CZS4
names: Similarity
messages: Belongs to the PRAME family.

9915:LOC109559712
gene id: 9915:LOC109559712
uniprot id: A0A6P5BVM4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109560612
gene id: 9915:LOC109560612
uniprot id: A0A6P5BZ12
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

9915:NPM3
gene id: 9915:NPM3
uniprot id: A0A6P5BGV3
uniprot id: A0A6P5BHA6
names: Similarity
messages: Belongs to the nucleoplasmin family.

9915:LOC109570482
gene id: 9915:LOC109570482
uniprot id: A0A6P5D1S0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:SERBP1
gene id: 9915:SERBP1
uniprot id: A0A6P5B2Q2
uniprot id: A0A6P5B7K0
uniprot id: A0A6P5BNZ9
uniprot id: A0A6P5BP29
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:LOC109560891
gene id: 9915:LOC109560891
uniprot id: A0A6P5C095
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:HGS
gene id: 9915:HGS
uniprot id: A0A6P5DG72
uniprot id: A0A6P5DGX3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane
messages: Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.
messages: multivesicular body membrane

9915:TANGO6
gene id: 9915:TANGO6
uniprot id: A0A6P5D882
uniprot id: A0A6P5D9T2
uniprot id: A0A6P5DAM8
names: Similarity
messages: Belongs to the Tango6 family.

9915:LOC109568889
gene id: 9915:LOC109568889
uniprot id: A0A6P5CXD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MDM4
gene id: 9915:MDM4
uniprot id: A0A6P5D2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM2/MDM4 family.
messages: Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain.
messages: Nucleus

9915:TMEM35A
gene id: 9915:TMEM35A
uniprot id: A0A6P5BMP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

9915:LOC109560141
gene id: 9915:LOC109560141
uniprot id: A0A6P5BWM5
names: Similarity
messages: Belongs to the histone H2B family.

9915:WDR24
gene id: 9915:WDR24
uniprot id: A0A6P5E1E7
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

9915:FZR1
gene id: 9915:FZR1
uniprot id: A0A6P5C367
uniprot id: A0A6P5C3H5
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

9915:LOC109562119
gene id: 9915:LOC109562119
uniprot id: A0A6P5C4T9
uniprot id: A0A6P5C4W8
uniprot id: A0A6P5C4W9
uniprot id: A0A6P5C685
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:EOGT
gene id: 9915:EOGT
uniprot id: A0A6P5DTZ4
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

9915:ACADSB
gene id: 9915:ACADSB
uniprot id: A0A6P5E1H7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9915:CHST12
gene id: 9915:CHST12
uniprot id: A0A6P5E0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

9915:PMS1
gene id: 9915:PMS1
uniprot id: A0A6P5CI80
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

9915:PDE4B
gene id: 9915:PDE4B
uniprot id: A0A6P5BP04
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

9915:USE1
gene id: 9915:USE1
uniprot id: A0A6P5C1I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109553934
gene id: 9915:LOC109553934
uniprot id: A0A6P5BJ36
names: Subcellular Location Annotation
messages: Membrane

9915:FAM173A
gene id: 9915:FAM173A
uniprot id: A0A6P5DZG8
uniprot id: A0A6P5E2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

9915:SH3BP5L
gene id: 9915:SH3BP5L
uniprot id: A0A6P5C5I0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

9915:ACADS
gene id: 9915:ACADS
uniprot id: A0A6P5D4V3
uniprot id: A0A6P5D8Q1
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

9915:TMEM126B
gene id: 9915:TMEM126B
uniprot id: A0A6P5BKT1
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109555158
gene id: 9915:LOC109555158
uniprot id: A0A6P5BLL5
uniprot id: A0A6P5BLN5
names: Function
names: Subcellular Location Annotation
messages: Nucleus speckle
messages: Plays a role in alternative splicing of pre-mRNAs, possibly by contributing to the selection of non-consensus donor sites.
messages: nucleoplasm

9915:KCNK17
gene id: 9915:KCNK17
uniprot id: A0A6P5DU71
uniprot id: A0A6P5DVE3
uniprot id: A0A6P5DXX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

9915:PCSK2
gene id: 9915:PCSK2
uniprot id: A0A6P5CVI0
names: Similarity
messages: Belongs to the peptidase S8 family.

9915:ADGRD2
gene id: 9915:ADGRD2
uniprot id: A0A6P5CJV8
uniprot id: A0A6P5CL45
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:THYN1
gene id: 9915:THYN1
uniprot id: A0A6P5CXL4
uniprot id: A0A6P5CZ68
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9915:GTF2A1L
gene id: 9915:GTF2A1L
uniprot id: A0A6P5CJK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

9915:NXPH4
gene id: 9915:NXPH4
uniprot id: A0A6P5BAT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: Secreted

9915:SPEN
gene id: 9915:SPEN
uniprot id: A0A6P5D1B7
uniprot id: A0A6P5D2R5
names: Similarity
messages: Belongs to the RRM Spen family.

9915:FLT4
gene id: 9915:FLT4
uniprot id: A0A6P5C0Y5
uniprot id: A0A6P5C188
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Nucleus

9915:PSMC4
gene id: 9915:PSMC4
uniprot id: A0A6P5DC43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC4 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
messages: Cytoplasm

9915:OCLN
gene id: 9915:OCLN
uniprot id: A0A6P5DK28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

9915:LOC109578076
gene id: 9915:LOC109578076
uniprot id: A0A6P5DW76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:FAM212B
gene id: 9915:FAM212B
uniprot id: A0A6P5BNH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

9915:NME2
gene id: 9915:NME2
uniprot id: A0A6P5DGZ6
names: Similarity
messages: Belongs to the NDK family.

9915:ALOX5
gene id: 9915:ALOX5
uniprot id: A0A6P5BB38
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TMTC3
gene id: 9915:TMTC3
uniprot id: A0A6P5BE30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

9915:MASP1
gene id: 9915:MASP1
uniprot id: A0A6P5B5W1
uniprot id: A0A6P5B5Y4
uniprot id: A0A6P5B5Y7
uniprot id: A0A6P5BJE6
uniprot id: A0A6P5BQ49
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:CASD1
gene id: 9915:CASD1
uniprot id: A0A6P5BAA1
uniprot id: A0A6P5BDV2
uniprot id: A0A6P5BLN3
uniprot id: A0A6P5BRS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

9915:PKD1
gene id: 9915:PKD1
uniprot id: A0A6P5DY09
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:UBALD2
gene id: 9915:UBALD2
uniprot id: A0A6P5DIZ0
uniprot id: A0A6P5DK19
names: Similarity
messages: Belongs to the UBALD family.

9915:CALU
gene id: 9915:CALU
uniprot id: A0A6P5B856
uniprot id: A0A6P5BR00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus
messages: Melanosome
messages: Membrane
messages: Sarcoplasmic reticulum lumen
messages: Secreted

9915:C29H11orf54
gene id: 9915:C29H11orf54
uniprot id: A0A6P5BCD1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

9915:LOC109574398
gene id: 9915:LOC109574398
uniprot id: A0A6P5DL14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

9915:FAM53B
gene id: 9915:FAM53B
uniprot id: A0A6P5E137
uniprot id: A0A6P5E1R4
names: Similarity
messages: Belongs to the FAM53 family.

9915:LOC109555916
gene id: 9915:LOC109555916
uniprot id: A0A6P5B693
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

9915:ADAM15
gene id: 9915:ADAM15
uniprot id: A0A6P5AS28
uniprot id: A0A6P5AS39
uniprot id: A0A6P5AS63
uniprot id: A0A6P5AS82
uniprot id: A0A6P5AYM1
uniprot id: A0A6P5AYP1
uniprot id: A0A6P5BAG7
uniprot id: A0A6P5BID8
uniprot id: A0A6P5BIN1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:C13H20orf27
gene id: 9915:C13H20orf27
uniprot id: A0A6P5CN29
names: Similarity
messages: Belongs to the UPF0687 family.

9915:SLC16A6
gene id: 9915:SLC16A6
uniprot id: A0A6P5DCV9
uniprot id: A0A6P5DER7
names: Subcellular Location Annotation
messages: Membrane

9915:WDR76
gene id: 9915:WDR76
uniprot id: A0A6P5DKW2
uniprot id: A0A6P5DM81
uniprot id: A0A6P5DPJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: Interacts with CUL4A and/or CUL4B.
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

9915:LOC109555229
gene id: 9915:LOC109555229
uniprot id: A0A6P5B3I2
names: Similarity
messages: Belongs to the glycosyltransferase 28 family.

9915:SST
gene id: 9915:SST
uniprot id: A0A6P5CDB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

9915:LOC109560203
gene id: 9915:LOC109560203
uniprot id: A0A6P5BXG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane
messages: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.

9915:TCTEX1D2
gene id: 9915:TCTEX1D2
uniprot id: A0A6P5BP40
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

9915:LOC109568872
gene id: 9915:LOC109568872
uniprot id: A0A6P5CUT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569027
gene id: 9915:LOC109569027
uniprot id: A0A6P5CV53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109569165
gene id: 9915:LOC109569165
uniprot id: A0A6P5CWB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109577386
gene id: 9915:LOC109577386
uniprot id: A0A6P5DV35
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109568939
gene id: 9915:LOC109568939
uniprot id: A0A6P5CUY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PSMD9
gene id: 9915:PSMD9
uniprot id: A0A6P5D903
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

9915:PCNP
gene id: 9915:PCNP
uniprot id: A0A6P5CUC4
uniprot id: A0A6P5CV47
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

9915:CHST1
gene id: 9915:CHST1
uniprot id: A0A6P5D1D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

9915:KRT8
gene id: 9915:KRT8
uniprot id: A0A6P5BFJ8
names: Similarity
messages: Belongs to the intermediate filament family.

9915:SH2B1
gene id: 9915:SH2B1
uniprot id: A0A6P5DWW5
uniprot id: A0A6P5DX07
names: Similarity
messages: Belongs to the SH2B adapter family.

9915:IRF4
gene id: 9915:IRF4
uniprot id: A0A6P5DTV9
uniprot id: A0A6P5DV77
uniprot id: A0A6P5DXQ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

9915:PIGU
gene id: 9915:PIGU
uniprot id: A0A6P5CQ78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:LOC109578221
gene id: 9915:LOC109578221
uniprot id: A0A6P5DWS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9915:TESMIN
gene id: 9915:TESMIN
uniprot id: A0A6P5BJQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

9915:LOC109572550
gene id: 9915:LOC109572550
uniprot id: A0A6P5D9T4
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

9915:NECAP1
gene id: 9915:NECAP1
uniprot id: A0A6P5BVA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NECAP family.
messages: Involved in endocytosis.
messages: clathrin-coated vesicle membrane

9915:TMEM45A
gene id: 9915:TMEM45A
uniprot id: A0A6P5CKS7
uniprot id: A0A6P5CLC9
uniprot id: A0A6P5CM15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

9915:RBM3
gene id: 9915:RBM3
uniprot id: A0A6P5BMC3
uniprot id: A0A6P5BMC8
names: Subcellular Location Annotation
messages: Cytoplasm

9915:ACE2
gene id: 9915:ACE2
uniprot id: A0A6P5BMB1
uniprot id: A0A6P5BMB2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

9915:KCNN1
gene id: 9915:KCNN1
uniprot id: A0A6P5C1E5
names: Subcellular Location Annotation
messages: Membrane

9915:CAPZA2
gene id: 9915:CAPZA2
uniprot id: A0A6P5B758
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

9915:SLC25A37
gene id: 9915:SLC25A37
uniprot id: A0A6P5C8A3
uniprot id: A0A6P5C8M3
uniprot id: A0A6P5C8U5
uniprot id: A0A6P5C8U8
uniprot id: A0A6P5C9U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:LOC109574801
gene id: 9915:LOC109574801
uniprot id: A0A6P5DM60
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

9915:METAP1D
gene id: 9915:METAP1D
uniprot id: A0A6P5CK20
uniprot id: A0A6P5CLA1
uniprot id: A0A6P5CLN7
uniprot id: A0A6P5CLQ4
uniprot id: A0A6P5CNF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109554263
gene id: 9915:LOC109554263
uniprot id: A0A6P5BJM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109575684
gene id: 9915:LOC109575684
uniprot id: A0A6P5DNT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

9915:LOC109564525
gene id: 9915:LOC109564525
uniprot id: A0A6P5CCI7
names: Similarity
messages: Belongs to the multicopper oxidase family.

9915:LOC109578093
gene id: 9915:LOC109578093
uniprot id: A0A6P5DXE3
names: Similarity
messages: Belongs to the YY transcription factor family.

9915:HS3ST3A1
gene id: 9915:HS3ST3A1
uniprot id: A0A6P5DIX2
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:HSPB2
gene id: 9915:HSPB2
uniprot id: A0A6P5CVS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

9915:GTPBP3
gene id: 9915:GTPBP3
uniprot id: A0A6P5C1G9
uniprot id: A0A6P5C1H3
uniprot id: A0A6P5C1U4
uniprot id: A0A6P5C2L1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

9915:SFRP4
gene id: 9915:SFRP4
uniprot id: A0A6P5BBI2
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:CGA
gene id: 9915:CGA
uniprot id: A0A6P5CAY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. The active hormones thyrotropin, lutropin and follitropin are heterodimers composed of CGA, a common alpha chain described here and a unique beta chain which confers their biological specificity to the hormones: TSHB for thyrotropin, LHB for lutropin and FSHB for follitropin.
messages: Secreted
messages: Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

9915:BTAF1
gene id: 9915:BTAF1
uniprot id: A0A6P5E0D5
names: Subcellular Location Annotation
messages: Nucleus

9915:ERLIN2
gene id: 9915:ERLIN2
uniprot id: A0A6P5AQI6
uniprot id: A0A6P5BHD1
uniprot id: A0A6P5BHS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Endoplasmic reticulum membrane
messages: Mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway.
messages: Membrane

9915:LOC109560857
gene id: 9915:LOC109560857
uniprot id: A0A6P5BZZ3
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC39A3
gene id: 9915:SLC39A3
uniprot id: A0A6P5C3I1
names: Subcellular Location Annotation
messages: Membrane

9915:AP2B1
gene id: 9915:AP2B1
uniprot id: A0A6P5DFA5
uniprot id: A0A6P5DGW9
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

9915:DDX10
gene id: 9915:DDX10
uniprot id: A0A6P5CUK6
names: Similarity
messages: Belongs to the DEAD box helicase family.

9915:MCM9
gene id: 9915:MCM9
uniprot id: A0A6P5CC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Chromosome
messages: Nucleus

9915:ANP32E
gene id: 9915:ANP32E
uniprot id: A0A6P5BMX4
names: Similarity
messages: Belongs to the ANP32 family.

9915:FAN1
gene id: 9915:FAN1
uniprot id: A0A6P5DKV7
uniprot id: A0A6P5DLG5
uniprot id: A0A6P5DPI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

9915:SETD1B
gene id: 9915:SETD1B
uniprot id: A0A6P5D554
names: Subcellular Location Annotation
messages: Chromosome

9915:BOLA3
gene id: 9915:BOLA3
uniprot id: A0A6P5CII1
names: Similarity
messages: Belongs to the BolA/IbaG family.

9915:EXTL2
gene id: 9915:EXTL2
uniprot id: A0A6P5B1Q0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:PHGDH
gene id: 9915:PHGDH
uniprot id: A0A6P5BN75
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

9915:FBLN2
gene id: 9915:FBLN2
uniprot id: A0A6P5DTB3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:PRKCDBP
gene id: 9915:PRKCDBP
uniprot id: A0A6P5D2B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9915:LOC109558366
gene id: 9915:LOC109558366
uniprot id: A0A6P5BE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC16A10
gene id: 9915:SLC16A10
uniprot id: A0A6P5CAY1
names: Subcellular Location Annotation
messages: Membrane

9915:BTC
gene id: 9915:BTC
uniprot id: A0A6P5BWG7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:TARDBP
gene id: 9915:TARDBP
uniprot id: A0A6P5D3A1
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109561018
gene id: 9915:LOC109561018
uniprot id: A0A6P5C194
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:STRN
gene id: 9915:STRN
uniprot id: A0A6P5CGF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

9915:NIM1K
gene id: 9915:NIM1K
uniprot id: A0A6P5DKK5
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:SEC22C
gene id: 9915:SEC22C
uniprot id: A0A6P5DPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

9915:LIF
gene id: 9915:LIF
uniprot id: A0A6P5D7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LIF/OSM family.
messages: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
messages: Secreted

9915:KCNA5
gene id: 9915:KCNA5
uniprot id: A0A6P5BVF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. A (Shaker) (TC 1.A.1.2) subfamily. Kv1.5/KCNA5 sub-subfamily.
messages: Cell membrane
messages: Membrane

9915:LOC109564485
gene id: 9915:LOC109564485
uniprot id: A0A6P5CDG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SLC35E3
gene id: 9915:SLC35E3
uniprot id: A0A6P5BT54
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109554174
gene id: 9915:LOC109554174
uniprot id: A0A6P5AZU8
uniprot id: A0A6P5BJ76
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:ACOT8
gene id: 9915:ACOT8
uniprot id: A0A6P5CR82
uniprot id: A0A6P5CS20
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

9915:STMN4
gene id: 9915:STMN4
uniprot id: A0A6P5C6S5
uniprot id: A0A6P5C6U6
uniprot id: A0A6P5C731
uniprot id: A0A6P5C852
names: Similarity
messages: Belongs to the stathmin family.

9915:LOC109571547
gene id: 9915:LOC109571547
uniprot id: A0A6P5D7C1
uniprot id: A0A6P5D8A8
names: Similarity
messages: Belongs to the GST superfamily. Theta family.

9915:LOC109558768
gene id: 9915:LOC109558768
uniprot id: A0A6P5BS92
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:STK33
gene id: 9915:STK33
uniprot id: A0A6P5D1W6
uniprot id: A0A6P5D2Z6
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:IRX5
gene id: 9915:IRX5
uniprot id: A0A6P5D792
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

9915:SARDH
gene id: 9915:SARDH
uniprot id: A0A6P5CM29
names: Similarity
messages: Belongs to the GcvT family.

9915:OS9
gene id: 9915:OS9
uniprot id: A0A6P5BTE4
uniprot id: A0A6P5BTE5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum lumen

9915:GORASP2
gene id: 9915:GORASP2
uniprot id: A0A6P5CLR5
uniprot id: A0A6P5CMX3
names: Similarity
messages: Belongs to the GORASP family.

9915:OTUD7B
gene id: 9915:OTUD7B
uniprot id: A0A6P5B5F3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

9915:C1QBP
gene id: 9915:C1QBP
uniprot id: A0A6P5DHB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAM33 family.
messages: Cell membrane

9915:LOC109556976
gene id: 9915:LOC109556976
uniprot id: A0A6P5BQ61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109564451
gene id: 9915:LOC109564451
uniprot id: A0A6P5CCQ3
names: Subcellular Location Annotation
messages: Nucleus

9915:LPCAT3
gene id: 9915:LPCAT3
uniprot id: A0A6P5BMM8
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109577299
gene id: 9915:LOC109577299
uniprot id: A0A6P5DXS9
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

9915:ZDHHC8
gene id: 9915:ZDHHC8
uniprot id: A0A6P5D6V4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane

9915:LOC109565066
gene id: 9915:LOC109565066
uniprot id: A0A6P5CF39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

9915:SLC39A7
gene id: 9915:SLC39A7
uniprot id: A0A6P5DQX9
names: Subcellular Location Annotation
messages: Membrane

9915:POU4F3
gene id: 9915:POU4F3
uniprot id: A0A6P5C146
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

9915:LOC109572162
gene id: 9915:LOC109572162
uniprot id: A0A6P5DA27
names: Subcellular Location Annotation
messages: Membrane

9915:ADAMTS3
gene id: 9915:ADAMTS3
uniprot id: A0A6P5BZL3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:POLB
gene id: 9915:POLB
uniprot id: A0A6P5BHZ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: Cytoplasm
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

9915:LOC109569427
gene id: 9915:LOC109569427
uniprot id: A0A6P5CYX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109567853
gene id: 9915:LOC109567853
uniprot id: A0A6P5CT68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9915:LOC109556000
gene id: 9915:LOC109556000
uniprot id: A0A6P5BNN9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

9915:DHRS7
gene id: 9915:DHRS7
uniprot id: A0A6P5CGV6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

9915:SMAGP
gene id: 9915:SMAGP
uniprot id: A0A6P5BN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAGP family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

9915:CAP1
gene id: 9915:CAP1
uniprot id: A0A6P5BIK1
uniprot id: A0A6P5BPI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CAP family.
messages: Cell membrane
messages: Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity.
messages: Homodimer. Binds actin monomers.
messages: Membrane

9915:EXOC6
gene id: 9915:EXOC6
uniprot id: A0A6P5ANX1
uniprot id: A0A6P5BGF9
uniprot id: A0A6P5BGY4
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

9915:PSMC3IP
gene id: 9915:PSMC3IP
uniprot id: A0A6P5DD72
names: Subcellular Location Annotation
messages: Nucleus

9915:EXT1
gene id: 9915:EXT1
uniprot id: A0A6P5CUH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane
messages: Forms a homo/heterooligomeric complex with EXT2. Interacts with NDST1.
messages: Membrane
messages: cis-Golgi network membrane

9915:NCSTN
gene id: 9915:NCSTN
uniprot id: A0A6P5DZV7
uniprot id: A0A6P5E2H3
uniprot id: A0A6P5E2W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

9915:C17H12orf65
gene id: 9915:C17H12orf65
uniprot id: A0A6P5D4E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

9915:DHPS
gene id: 9915:DHPS
uniprot id: A0A6P5C2D6
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

9915:MAP4
gene id: 9915:MAP4
uniprot id: A0A6P5DPL0
names: Subcellular Location Annotation
messages: cytoskeleton

9915:A4GNT
gene id: 9915:A4GNT
uniprot id: A0A6P5CE93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

9915:DIS3L2
gene id: 9915:DIS3L2
uniprot id: A0A6P5D779
uniprot id: A0A6P5D9P6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

9915:MOSPD1
gene id: 9915:MOSPD1
uniprot id: A0A6P5B4G8
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

9915:KEG07 p08
gene id: 9915:KEG07_p08
uniprot id: E7BTI4
uniprot id: Q8LTZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c. Component of an ATP synthase complex composed of ATP5PB, ATP5MC1, ATP5F1E, ATP5PD, ATP5ME, ATP5PF, ATP5MF, MT-ATP6, MT-ATP8, ATP5F1A, ATP5F1B, ATP5F1D, ATP5F1C, ATP5PO, ATP5MG, ATP5MK and ATP5MJ (By similarity). Interacts with DNAJC30; interaction is direct (By similarity).
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

9915:TUBB3
gene id: 9915:TUBB3
uniprot id: A0A6P5DA34
uniprot id: A0A6P5DBW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

9915:ITGA6
gene id: 9915:ITGA6
uniprot id: A0A6P5CL56
uniprot id: A0A6P5CLM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

9915:LOC109568695
gene id: 9915:LOC109568695
uniprot id: A0A6P5CUF3
uniprot id: A0A6P5CVD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

9915:PAPPA
gene id: 9915:PAPPA
uniprot id: A0A6P5C6E9
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:FLCN
gene id: 9915:FLCN
uniprot id: A0A6P5DED8
uniprot id: A0A6P5DG31
uniprot id: A0A6P5DGT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

9915:CACNA1F
gene id: 9915:CACNA1F
uniprot id: A0A6P5AWI3
uniprot id: A0A6P5BEH4
uniprot id: A0A6P5BL58
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

9915:LOC109561241
gene id: 9915:LOC109561241
uniprot id: A0A6P5C0R4
uniprot id: A0A6P5C1S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:IL37
gene id: 9915:IL37
uniprot id: A0A6P5CH27
uniprot id: A0A6P5CIG2
uniprot id: A0A6P5CIY6
uniprot id: A0A6P5CK14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-1 family.
messages: Secreted

9915:LIPT2
gene id: 9915:LIPT2
uniprot id: A0A6P5D035
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

9915:TEKT3
gene id: 9915:TEKT3
uniprot id: A0A6P5DLZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms filamentous polymers in the walls of ciliary and flagellar microtubules. Required for normal sperm mobility.
messages: flagellum

9915:CRISP1
gene id: 9915:CRISP1
uniprot id: A0A6P5DSC4
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:HIBCH
gene id: 9915:HIBCH
uniprot id: A0A6P5CH53
uniprot id: A0A6P5CHR0
uniprot id: A0A6P5CI48
uniprot id: A0A6P5CI61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
messages: Mitochondrion

9915:LIMS1
gene id: 9915:LIMS1
uniprot id: A0A6P5CIF8
uniprot id: A0A6P5CJW1
uniprot id: A0A6P5CKN6
uniprot id: A0A6P5CKP1
uniprot id: A0A6P5CLL6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter protein in a cytoplasmic complex linking beta-integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.
messages: Cell membrane
messages: Part of the heterotrimeric IPP complex composed of integrin-linked kinase (ILK), LIMS1 or LIMS2, and PARVA.
messages: focal adhesion

9915:LOC109565827
gene id: 9915:LOC109565827
uniprot id: A0A6P5CJ57
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

9915:TRDN
gene id: 9915:TRDN
uniprot id: A0A6P5C9P5
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

9915:PPDPF
gene id: 9915:PPDPF
uniprot id: A0A6P5CRD6
names: Similarity
messages: Belongs to the PPDPF family.

9915:CDR2L
gene id: 9915:CDR2L
uniprot id: A0A6P5DKR9
names: Similarity
messages: Belongs to the CDR2 family.

9915:ADNP
gene id: 9915:ADNP
uniprot id: A0A6P5CR27
names: Subcellular Location Annotation
messages: Nucleus

9915:PSMD4
gene id: 9915:PSMD4
uniprot id: A0A6P5BLJ2
uniprot id: A0A6P5BLJ5
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

9915:STXBP5L
gene id: 9915:STXBP5L
uniprot id: A0A6P5E3N7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

9915:LOC109564436
gene id: 9915:LOC109564436
uniprot id: A0A6P5CCC7
names: Subcellular Location Annotation
messages: Nucleus

9915:LOC109569633
gene id: 9915:LOC109569633
uniprot id: A0A6P5CXM9
uniprot id: A0A6P5CYE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

9915:SERPINA1
gene id: 9915:SERPINA1
uniprot id: A0A6P5DQE7
names: Similarity
messages: Belongs to the serpin family.

9915:BRI3
gene id: 9915:BRI3
uniprot id: A0A6P5DWK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRI3 family.
messages: Membrane
messages: perinuclear region

9915:LOC109569225
gene id: 9915:LOC109569225
uniprot id: A0A6P5CWJ4
names: Similarity
messages: Belongs to the peptidase M10A family.

9915:SYNDIG1L
gene id: 9915:SYNDIG1L
uniprot id: A0A6P5CFU3
uniprot id: A0A6P5CGF5
names: Similarity
messages: Belongs to the CD225/Dispanin family.

9915:SPPL3
gene id: 9915:SPPL3
uniprot id: A0A6P5D4M4
uniprot id: A0A6P5D5X7
uniprot id: A0A6P5D6Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

9915:MAP4K3
gene id: 9915:MAP4K3
uniprot id: A0A6P5CHW3
uniprot id: A0A6P5CIV8
uniprot id: A0A6P5CK35
names: Function
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

9915:TMEM8A
gene id: 9915:TMEM8A
uniprot id: A0A6P5DYF0
uniprot id: A0A6P5DZ83
uniprot id: A0A6P5E1W7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109569007
gene id: 9915:LOC109569007
uniprot id: A0A6P5CXN5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:SCG2
gene id: 9915:SCG2
uniprot id: A0A6P5D4L8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chromogranin/secretogranin protein family.
messages: Interacts with Secretogranin III/SCG3.
messages: Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
messages: Secreted

9915:ZDHHC22
gene id: 9915:ZDHHC22
uniprot id: A0A6P5CCL8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

9915:MAP3K14
gene id: 9915:MAP3K14
uniprot id: A0A6P5DJF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

9915:LOC109563957
gene id: 9915:LOC109563957
uniprot id: A0A6P5CBZ9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

9915:CNOT1
gene id: 9915:CNOT1
uniprot id: A0A6P5D7Z5
uniprot id: A0A6P5D7Z8
uniprot id: A0A6P5D803
uniprot id: A0A6P5D838
uniprot id: A0A6P5D843
uniprot id: A0A6P5D9N3
uniprot id: A0A6P5D9N9
uniprot id: A0A6P5DAH4
uniprot id: A0A6P5DAH9
uniprot id: A0A6P5DBL4
uniprot id: A0A6P5DBM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

9915:PIK3C3
gene id: 9915:PIK3C3
uniprot id: A0A6P5DUM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

9915:INPP5A
gene id: 9915:INPP5A
uniprot id: A0A6P5E0F8
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

9915:LOC109575074
gene id: 9915:LOC109575074
uniprot id: A0A6P5DKP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

9915:GALNS
gene id: 9915:GALNS
uniprot id: A0A6P5DAK0
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfatase family.
messages: Homodimer.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

9915:KIAA2022
gene id: 9915:KIAA2022
uniprot id: A0A6P5B542
names: Subcellular Location Annotation
messages: Nucleus

9915:MMRN1
gene id: 9915:MMRN1
uniprot id: A0A6P5BXH4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:GPX7
gene id: 9915:GPX7
uniprot id: A0A6P5BI34
names: Similarity
messages: Belongs to the glutathione peroxidase family.

9915:ODC1
gene id: 9915:ODC1
uniprot id: A0A6P5CKT4
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

9915:NCOR1
gene id: 9915:NCOR1
uniprot id: A0A6P5DD14
uniprot id: A0A6P5DD15
uniprot id: A0A6P5DD23
uniprot id: A0A6P5DD25
uniprot id: A0A6P5DD30
uniprot id: A0A6P5DD31
uniprot id: A0A6P5DD36
uniprot id: A0A6P5DD40
uniprot id: A0A6P5DEX2
uniprot id: A0A6P5DEX7
uniprot id: A0A6P5DEY2
uniprot id: A0A6P5DFF4
uniprot id: A0A6P5DG76
uniprot id: A0A6P5DG82
uniprot id: A0A6P5DG91
uniprot id: A0A6P5DG96
names: Similarity
messages: Belongs to the N-CoR nuclear receptor corepressors family.

9915:LOC109578465
gene id: 9915:LOC109578465
uniprot id: A0A6P5DY29
uniprot id: A0A6P5DYX1
uniprot id: A0A6P5E1K9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

9915:EFNB2
gene id: 9915:EFNB2
uniprot id: A0A6P5CQV8
names: Caution
names: Similarity
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SGTA
gene id: 9915:SGTA
uniprot id: A0A6P5C398
uniprot id: A0A6P5C4J7
names: Similarity
messages: Belongs to the SGT family.

9915:LOC109575985
gene id: 9915:LOC109575985
uniprot id: A0A6P5DN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:MYOCD
gene id: 9915:MYOCD
uniprot id: A0A6P5DEX5
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

9915:BCL2L10
gene id: 9915:BCL2L10
uniprot id: A0A6P5CC88
names: Similarity
messages: Belongs to the Bcl-2 family.

9915:LOC109574360
gene id: 9915:LOC109574360
uniprot id: A0A6P5DKR3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

9915:LOC109560595
gene id: 9915:LOC109560595
uniprot id: A0A6P5BZQ2
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

9915:VWA1
gene id: 9915:VWA1
uniprot id: A0A6P5D5U0
names: Subcellular Location Annotation
messages: Membrane
messages: basement membrane

9915:FOXD3
gene id: 9915:FOXD3
uniprot id: A0A6P5BHU0
names: Subcellular Location Annotation
messages: Nucleus

9915:NXPH1
gene id: 9915:NXPH1
uniprot id: A0A6P5BRD9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

9915:LOC109569003
gene id: 9915:LOC109569003
uniprot id: A0A6P5CW03
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TLR2
gene id: 9915:TLR2
uniprot id: A0A6P5D600
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). May also promote apoptosis in response to lipoproteins. Forms activation clusters composed of several receptors depending on the ligand, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Forms the cluster TLR2:TLR6:CD14:CD36 in response to diacylated lipopeptides and TLR2:TLR1:CD14 in response to triacylated lipopeptides.
messages: Interacts with LY96, TLR1 and TLR6 (via extracellular domain). TLR2 seems to exist in heterodimers with either TLR1 or TLR6 before stimulation by the ligand. The heterodimers form bigger oligomers in response to their corresponding ligands as well as further heterotypic associations with other receptors such as CD14 and/or CD36. Binds MYD88 (via TIR domain). Interacts with TICAM1. Interacts with CNPY3. Interacts with ATG16L1. Interacts with PPP1R11. Interacts with TICAM2.
messages: Membrane
messages: Membrane raft
messages: phagosome membrane

9915:LOC109561244
gene id: 9915:LOC109561244
uniprot id: A0A6P5C121
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109558770
gene id: 9915:LOC109558770
uniprot id: A0A6P5BEP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:BCHE
gene id: 9915:BCHE
uniprot id: A0A6P5BB45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

9915:PIGM
gene id: 9915:PIGM
uniprot id: A0A6P5E0G3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

9915:LOC109576710
gene id: 9915:LOC109576710
uniprot id: A0A6P5DRN9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MED24
gene id: 9915:MED24
uniprot id: A0A6P5DJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 24 family.
messages: Nucleus

9915:KAT6A
gene id: 9915:KAT6A
uniprot id: A0A6P5AX36
uniprot id: A0A6P5BHB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

9915:TOP3B
gene id: 9915:TOP3B
uniprot id: A0A6P5D8Z2
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

9915:EBPL
gene id: 9915:EBPL
uniprot id: A0A6P5CNR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

9915:PAMR1
gene id: 9915:PAMR1
uniprot id: A0A6P5D2N8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:LOC109577904
gene id: 9915:LOC109577904
uniprot id: A0A6P5DZW1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

9915:ADRB1
gene id: 9915:ADRB1
uniprot id: A0A6P5B8B8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling (By similarity). Involved in the regulation of sleep/wake behaviors.
messages: Cell membrane
messages: Interacts (via C-terminus PDZ motif) with RAPGEF2; the interaction is direct. Interacts with GOPC, MAGI3 and DLG4.
messages: Membrane

9915:LOC109564308
gene id: 9915:LOC109564308
uniprot id: A0A6P5CDG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CEPT1
gene id: 9915:CEPT1
uniprot id: A0A6P5B1C6
uniprot id: A0A6P5BNJ3
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

9915:ICAM3
gene id: 9915:ICAM3
uniprot id: A0A6P5C248
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. ICAM family.
messages: Membrane

9915:ARL5B
gene id: 9915:ARL5B
uniprot id: A0A6P5CSC9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

9915:MED20
gene id: 9915:MED20
uniprot id: A0A6P5DSR1
uniprot id: A0A6P5DWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 20 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:PLXNA2
gene id: 9915:PLXNA2
uniprot id: A0A6P5D1M0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:CAPN10
gene id: 9915:CAPN10
uniprot id: A0A6P5BPT9
names: Similarity
messages: Belongs to the peptidase C2 family.

9915:RXRA
gene id: 9915:RXRA
uniprot id: A0A6P5CKR9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

9915:LOC109554215
gene id: 9915:LOC109554215
uniprot id: A0A6P5BJA5
names: Subcellular Location Annotation
messages: Membrane

9915:LOC109557335
gene id: 9915:LOC109557335
uniprot id: A0A6P5B6U2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

9915:SCAI
gene id: 9915:SCAI
uniprot id: A0A6P5CJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAI family.
messages: Cytoplasm
messages: Interacts with DIAPH1. Forms a nuclear ternary complex with MRTFA and SRF.
messages: Nucleus
messages: Tumor suppressor which functions to suppress MRTFA-induced SRF transcriptional activity.

9915:LOC109569547
gene id: 9915:LOC109569547
uniprot id: A0A6P5CX44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:TNFSF14
gene id: 9915:TNFSF14
uniprot id: A0A6P5C305
names: Similarity
messages: Belongs to the tumor necrosis factor family.

9915:LOC109565812
gene id: 9915:LOC109565812
uniprot id: A0A6P5CI30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 6 family.
messages: Membrane

9915:FAM110D
gene id: 9915:FAM110D
uniprot id: A0A6P5DSD3
names: Similarity
messages: Belongs to the FAM110 family.

9915:SLC25A28
gene id: 9915:SLC25A28
uniprot id: A0A6P5ANP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

9915:LOC109576711
gene id: 9915:LOC109576711
uniprot id: A0A6P5DV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109560101
gene id: 9915:LOC109560101
uniprot id: A0A6P5BWW2
names: Subcellular Location Annotation
messages: dendrite

9915:SYNE1
gene id: 9915:SYNE1
uniprot id: A0A6P5CDJ8
names: Similarity
messages: Belongs to the nesprin family.

9915:LOC109563499
gene id: 9915:LOC109563499
uniprot id: A0A6P5CAP9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

9915:NEK7
gene id: 9915:NEK7
uniprot id: A0A6P5D291
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:ZRANB1
gene id: 9915:ZRANB1
uniprot id: A0A6P5E4B6
names: Similarity
messages: Belongs to the peptidase C64 family.

9915:ATR
gene id: 9915:ATR
uniprot id: A0A6P5BUN6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. ATM subfamily.

9915:MED17
gene id: 9915:MED17
uniprot id: A0A6P5BKH7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:MAN2A1
gene id: 9915:MAN2A1
uniprot id: A0A6P5C631
uniprot id: A0A6P5C6I6
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

9915:KCNA10
gene id: 9915:KCNA10
uniprot id: A0A6P5BAN1
names: Subcellular Location Annotation
messages: Membrane

9915:POC5
gene id: 9915:POC5
uniprot id: A0A6P5CCT2
uniprot id: A0A6P5CD54
uniprot id: A0A6P5CF10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

9915:LOC109558818
gene id: 9915:LOC109558818
uniprot id: A0A6P5BS91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor T2R family.
messages: Membrane

9915:PSMD11
gene id: 9915:PSMD11
uniprot id: A0A6P5DGD0
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

9915:RPL21
gene id: 9915:RPL21
uniprot id: A0A6P5CNH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

9915:PDHA2
gene id: 9915:PDHA2
uniprot id: A0A6P5BWX7
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

9915:GAPDH
gene id: 9915:GAPDH
uniprot id: A0A6P5BSF2
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

9915:LOC109575179
gene id: 9915:LOC109575179
uniprot id: A0A6P5DP16
names: Similarity
messages: Belongs to the ENTREP family.

9915:UTP11
gene id: 9915:UTP11
uniprot id: A0A6P5BIN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

9915:NRCAM
gene id: 9915:NRCAM
uniprot id: A0A6P5B733
uniprot id: A0A6P5B735
uniprot id: A0A6P5BBG6
uniprot id: A0A6P5BBH2
uniprot id: A0A6P5BBH7
uniprot id: A0A6P5BK07
uniprot id: A0A6P5BK10
uniprot id: A0A6P5BQM0
uniprot id: A0A6P5BQM2
uniprot id: A0A6P5BQM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

9915:FXN
gene id: 9915:FXN
uniprot id: A0A6P5C7H1
names: Similarity
messages: Belongs to the frataxin family.

9915:PFKM
gene id: 9915:PFKM
uniprot id: A0A6P5BDN3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homo- and heterotetramers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:INTS12
gene id: 9915:INTS12
uniprot id: A0A6P5BXZ5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Integrator subunit 12 family.
messages: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, INTS11/CPSF3L and INTS12.
messages: Nucleus

9915:LOC109566811
gene id: 9915:LOC109566811
uniprot id: A0A6P5CP45
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit. Interacts with ASPM; the katanin complex formation KATNA1:KATNB1 is required for the association of ASPM. Interacts with dynein and NDEL1. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and DCAF1 proteins (EDVP complex). Interacts with KLHL42 (via the kelch domains). Interacts with CUL3; the interaction is enhanced by KLHL42. Interacts with KATNB1 and KATNBL1. Interacts with CAMSAP2 and CAMSAP3; leading to regulate the length of CAMSAP-decorated microtubule stretches.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Midbody
messages: Phosphorylation by DYRK2 triggers ubiquitination and subsequent degradation.
messages: The N-terminus is sufficient for interaction with microtubules, although high affinity binding to microtubules also requires an intact C-terminal domain and ATP, which promotes oligomerization.
messages: Ubiquitinated by the BCR(KLHL42) E3 ubiquitin ligase complex, leading to its proteasomal degradation. Ubiquitinated by the EDVP E3 ligase complex and subsequently targeted for proteasomal degradation.
messages: centrosome
messages: spindle
messages: spindle pole

9915:EXOSC3
gene id: 9915:EXOSC3
uniprot id: A0A6P5C859
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

9915:TXNL4A
gene id: 9915:TXNL4A
uniprot id: A0A6P5DZG6
uniprot id: A0A6P5DZY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

9915:HNRNPA2B1
gene id: 9915:HNRNPA2B1
uniprot id: A0A6P5BKA5
uniprot id: A0A6P5BQT7
uniprot id: A0A6P5BQT9
names: Subcellular Location Annotation
messages: Cytoplasmic granule
messages: extracellular exosome

9915:SYNGR2
gene id: 9915:SYNGR2
uniprot id: A0A6P5DFZ7
uniprot id: A0A6P5DID7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

9915:LOC109576405
gene id: 9915:LOC109576405
uniprot id: A0A6P5DQA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

9915:UBA52
gene id: 9915:UBA52
uniprot id: A0A6P5C1C2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Component of the 60S subunit of the ribosome. Ribosomal protein L40 is essential for translation of a subset of cellular transcripts, and especially for cap-dependent translation of vesicular stomatitis virus mRNAs.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus
messages: Ribosomal protein L40 is part of the 60S ribosomal subunit. Interacts with UBQLN1 (via UBA domain).

9915:KCNQ2
gene id: 9915:KCNQ2
uniprot id: A0A6P5CQ93
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109569766
gene id: 9915:LOC109569766
uniprot id: A0A6P5CZF8
uniprot id: A0A6P5D0Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109578087
gene id: 9915:LOC109578087
uniprot id: A0A6P5DZZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDIP1/LITAF family.
messages: Lysosome membrane
messages: Membrane

9915:CALB1
gene id: 9915:CALB1
uniprot id: A0A6P5CTY8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.
messages: Interacts with RANBP9.

9915:LOC109560316
gene id: 9915:LOC109560316
uniprot id: A0A6P5BXD1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

9915:DLGAP4
gene id: 9915:DLGAP4
uniprot id: A0A6P5CPB5
uniprot id: A0A6P5CQE8
uniprot id: A0A6P5CQY0
uniprot id: A0A6P5CSX3
names: Similarity
messages: Belongs to the SAPAP family.

9915:TSHZ2
gene id: 9915:TSHZ2
uniprot id: A0A6P5CR41
uniprot id: A0A6P5CSC0
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

9915:ZFP36L2
gene id: 9915:ZFP36L2
uniprot id: A0A6P5CHR6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

9915:SMAD7
gene id: 9915:SMAD7
uniprot id: A0A6P5DVQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

9915:LOC109577822
gene id: 9915:LOC109577822
uniprot id: A0A6P5DV69
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

9915:LOC109562004
gene id: 9915:LOC109562004
uniprot id: A0A6P5C4F8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DONSON family.
messages: Nucleus

9915:ARTN
gene id: 9915:ARTN
uniprot id: A0A6P5BJD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

9915:GATA3
gene id: 9915:GATA3
uniprot id: A0A6P5CR86
uniprot id: A0A6P5CUQ0
names: Subcellular Location Annotation
messages: Nucleus

9915:SERINC4
gene id: 9915:SERINC4
uniprot id: A0A6P5DM86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

9915:MED10
gene id: 9915:MED10
uniprot id: A0A6P5DLF0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11. The MED12, MED13, CCNC and CDK8 subunits form a distinct module termed the CDK8 module. Mediator containing the CDK8 module is less active than Mediator lacking this module in supporting transcriptional activation. Individual preparations of the Mediator complex lacking one or more distinct subunits have been variously termed ARC, CRSP, DRIP, PC2, SMCC and TRAP.
messages: Nucleus

9915:FAM199X
gene id: 9915:FAM199X
uniprot id: A0A6P5BMA3
uniprot id: A0A6P5BMA4
names: Similarity
messages: Belongs to the FAM199 family.

9915:PEPD
gene id: 9915:PEPD
uniprot id: A0A6P5D8E5
uniprot id: A0A6P5DAU9
names: Similarity
messages: Belongs to the peptidase M24B family.

9915:SRPX
gene id: 9915:SRPX
uniprot id: A0A6P5BGB4
uniprot id: A0A6P5BML1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:FOXO6
gene id: 9915:FOXO6
uniprot id: A0A6P5BII2
names: Subcellular Location Annotation
messages: Nucleus

9915:F12
gene id: 9915:F12
uniprot id: A0A6P5C472
uniprot id: A0A6P5C569
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

9915:FZD5
gene id: 9915:FZD5
uniprot id: A0A6P5D2C8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:LOC109565625
gene id: 9915:LOC109565625
uniprot id: A0A6P5CI17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MAP7D3
gene id: 9915:MAP7D3
uniprot id: A0A6P5AWU5
uniprot id: A0A6P5B2M9
uniprot id: A0A6P5BEQ1
names: Similarity
messages: Belongs to the MAP7 family.

9915:REEP4
gene id: 9915:REEP4
uniprot id: A0A6P5C8F7
uniprot id: A0A6P5C8M4
uniprot id: A0A6P5C8N2
uniprot id: A0A6P5C8N7
uniprot id: A0A6P5C9M7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:NUDT12
gene id: 9915:NUDT12
uniprot id: A0A6P5C5Z6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

9915:B9D2
gene id: 9915:B9D2
uniprot id: A0A6P5DDQ0
names: Subcellular Location Annotation
messages: cilium basal body

9915:SLC10A6
gene id: 9915:SLC10A6
uniprot id: A0A6P5BZK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane

9915:CASP2
gene id: 9915:CASP2
uniprot id: A0A6P5B8R6
uniprot id: A0A6P5BKW7
names: Similarity
messages: Belongs to the peptidase C14A family.

9915:CEP55
gene id: 9915:CEP55
uniprot id: A0A6P5BGW5
names: Subcellular Location Annotation
messages: Cytoplasm

9915:HSPB7
gene id: 9915:HSPB7
uniprot id: A0A6P5DMJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Nucleus

9915:CAV3
gene id: 9915:CAV3
uniprot id: A0A6P5DRJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

9915:IFI35
gene id: 9915:IFI35
uniprot id: A0A6P5DGD2
uniprot id: A0A6P5DJ94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NMI family.
messages: Cytoplasm
messages: Nucleus
messages: Secreted

9915:RAD21L1
gene id: 9915:RAD21L1
uniprot id: A0A6P5CPW5
uniprot id: A0A6P5CR74
uniprot id: A0A6P5CS75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

9915:LOC109555132
gene id: 9915:LOC109555132
uniprot id: A0A6P5BLG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 41 family. O-GlcNAc transferase subfamily.
messages: Cell projection
messages: Mitochondrion membrane

9915:KIFC2
gene id: 9915:KIFC2
uniprot id: A0A6P5CST2
uniprot id: A0A6P5CTU7
uniprot id: A0A6P5CU62
uniprot id: A0A6P5CVA5
uniprot id: A0A6P5CWB9
uniprot id: A0A6P5CWC6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

9915:LOC109564312
gene id: 9915:LOC109564312
uniprot id: A0A6P5CC46
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:PHTF1
gene id: 9915:PHTF1
uniprot id: A0A6P5B126
uniprot id: A0A6P5BNC6
uniprot id: A0A6P5BNE3
names: Subcellular Location Annotation
messages: Membrane

9915:GALNT16
gene id: 9915:GALNT16
uniprot id: A0A6P5CGS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:NEK3
gene id: 9915:NEK3
uniprot id: A0A6P5CLA7
uniprot id: A0A6P5CMM1
names: Similarity
messages: Belongs to the protein kinase superfamily.

9915:LOC109575953
gene id: 9915:LOC109575953
uniprot id: A0A6P5DNN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

9915:LOC109558740
gene id: 9915:LOC109558740
uniprot id: A0A6P5BS83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GOLT1B
gene id: 9915:GOLT1B
uniprot id: A0A6P5BUX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
messages: Membrane

9915:SNX18
gene id: 9915:SNX18
uniprot id: A0A6P5DN83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

9915:LOC109558307
gene id: 9915:LOC109558307
uniprot id: A0A6P5BE20
names: Similarity
messages: Belongs to the peptidase M1 family.

9915:LOC109569953
gene id: 9915:LOC109569953
uniprot id: A0A6P5D2U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:ARHGEF28
gene id: 9915:ARHGEF28
uniprot id: A0A6P5DJB1
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109568992
gene id: 9915:LOC109568992
uniprot id: A0A6P5CW85
names: Function
names: Subcellular Location Annotation
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:MRPL14
gene id: 9915:MRPL14
uniprot id: A0A6P5DWH0
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

9915:TAS1R1
gene id: 9915:TAS1R1
uniprot id: A0A6P5D2U8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

9915:LOC109557963
gene id: 9915:LOC109557963
uniprot id: A0A6P5BRH1
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

9915:BICC1
gene id: 9915:BICC1
uniprot id: A0A6P5BAM9
uniprot id: A0A6P5BIF8
uniprot id: A0A6P5BIS8
names: Similarity
messages: Belongs to the BicC family.

9915:WNT1
gene id: 9915:WNT1
uniprot id: A0A6P5BS69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

9915:TMEM33
gene id: 9915:TMEM33
uniprot id: A0A6P5BY39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

9915:TFEC
gene id: 9915:TFEC
uniprot id: A0A6P5B765
uniprot id: A0A6P5BQN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

9915:UPF1
gene id: 9915:UPF1
uniprot id: A0A6P5C0V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

9915:GALNT18
gene id: 9915:GALNT18
uniprot id: A0A6P5D215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

9915:LOC109572054
gene id: 9915:LOC109572054
uniprot id: A0A6P5DAW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

9915:D2HGDH
gene id: 9915:D2HGDH
uniprot id: A0A6P5B593
uniprot id: A0A6P5BJ25
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

9915:LOC109569343
gene id: 9915:LOC109569343
uniprot id: A0A6P5CW40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:GTPBP10
gene id: 9915:GTPBP10
uniprot id: A0A6P5BBZ9
uniprot id: A0A6P5BKB5
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

9915:SNRPA1
gene id: 9915:SNRPA1
uniprot id: A0A6P5DQI6
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

9915:ADAMTS20
gene id: 9915:ADAMTS20
uniprot id: A0A6P5BG41
uniprot id: A0A6P5BSX9
uniprot id: A0A6P5BT10
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

9915:FAM212A
gene id: 9915:FAM212A
uniprot id: A0A6P5DRG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INKA family.
messages: Nucleus

9915:PTRF
gene id: 9915:PTRF
uniprot id: A0A6P5DEY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

9915:METTL11B
gene id: 9915:METTL11B
uniprot id: A0A6P5D272
uniprot id: A0A6P5D3B6
uniprot id: A0A6P5D4I3
uniprot id: A0A6P5D5Y0
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

9915:RBM47
gene id: 9915:RBM47
uniprot id: A0A6P5BYE9
uniprot id: A0A6P5BYU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

9915:SLC1A2
gene id: 9915:SLC1A2
uniprot id: A0A6P5CYI1
uniprot id: A0A6P5CZJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

9915:NOB1
gene id: 9915:NOB1
uniprot id: A0A6P5DB67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

9915:LOC109554582
gene id: 9915:LOC109554582
uniprot id: A0A6P5BKM3
names: Subcellular Location Annotation
messages: Membrane

9915:APLP2
gene id: 9915:APLP2
uniprot id: A0A6P5AU74
uniprot id: A0A6P5BCI4
uniprot id: A0A6P5BJT5
uniprot id: A0A6P5BJZ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

9915:CUL5
gene id: 9915:CUL5
uniprot id: A0A6P5CVI4
names: Similarity
messages: Belongs to the cullin family.

9915:KHSRP
gene id: 9915:KHSRP
uniprot id: A0A6P5C314
names: Subcellular Location Annotation
messages: Nucleus

9915:SSBP2
gene id: 9915:SSBP2
uniprot id: A0A6P5C5R3
uniprot id: A0A6P5C669
names: Subcellular Location Annotation
messages: Nucleus

9915:DPY19L1
gene id: 9915:DPY19L1
uniprot id: A0A6P5B9H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

9915:HPS6
gene id: 9915:HPS6
uniprot id: A0A6P5E0G0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6. Interacts with HPS5 and HPS3. Interacts with biogenesis of lysosome-related organelles complex-1 (BLOC1). Interacts with AP-3 complex.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: Microsome membrane

9915:GLG1
gene id: 9915:GLG1
uniprot id: A0A6P5D5X6
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Golgi outpost
messages: Membrane
messages: microtubule organizing center

9915:MS4A8
gene id: 9915:MS4A8
uniprot id: A0A6P5BE07
names: Similarity
messages: Belongs to the MS4A family.

9915:KCNA1
gene id: 9915:KCNA1
uniprot id: A0A6P5BBT6
names: Subcellular Location Annotation
messages: Membrane

9915:CHRNE
gene id: 9915:CHRNE
uniprot id: A0A6P5DEB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

9915:NFASC
gene id: 9915:NFASC
uniprot id: A0A6P5D244
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

9915:TWF1
gene id: 9915:TWF1
uniprot id: A0A6P5BDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

9915:LOC109553169
gene id: 9915:LOC109553169
uniprot id: A0A6P5BH69
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

9915:SLC26A5
gene id: 9915:SLC26A5
uniprot id: A0A6P5BDJ8
uniprot id: A0A6P5BLH3
uniprot id: A0A6P5BRN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Cell membrane
messages: Membrane
messages: Motor protein that converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ.

9915:DUSP26
gene id: 9915:DUSP26
uniprot id: A0A6P5BHX9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

9915:CDKN1B
gene id: 9915:CDKN1B
uniprot id: A0A6P5BV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

9915:MFSD4B
gene id: 9915:MFSD4B
uniprot id: A0A6P5CBL2
names: Subcellular Location Annotation
messages: Membrane

9915:SEC23A
gene id: 9915:SEC23A
uniprot id: A0A6P5DN08
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

9915:STAG3
gene id: 9915:STAG3
uniprot id: A0A6P5E093
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

9915:LOC109569952
gene id: 9915:LOC109569952
uniprot id: A0A6P5CZ76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:LOC109578822
gene id: 9915:LOC109578822
uniprot id: A0A6P5DZW2
uniprot id: A0A6P5E0P7
uniprot id: A0A6P5E3N0
names: Similarity
messages: Belongs to the NXPE family.

9915:TPD52
gene id: 9915:TPD52
uniprot id: A0A6P5CTE2
names: Similarity
messages: Belongs to the TPD52 family.

9915:LOC109566483
gene id: 9915:LOC109566483
uniprot id: A0A6P5CLR8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space
messages: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases.

9915:LOC109577067
gene id: 9915:LOC109577067
uniprot id: A0A6P5DTX9
uniprot id: A0A6P5DWR2
names: Similarity
messages: Belongs to the MHC class I family.

9915:EFEMP1
gene id: 9915:EFEMP1
uniprot id: A0A6P5CIB6
uniprot id: A0A6P5CKH8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

9915:SEPHS2
gene id: 9915:SEPHS2
uniprot id: A0A6P5E2G0
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

9915:STX2
gene id: 9915:STX2
uniprot id: A0A6P5D507
uniprot id: A0A6P5D6F0
names: Similarity
messages: Belongs to the syntaxin family.

9915:PLD1
gene id: 9915:PLD1
uniprot id: A0A6P5B9X4
uniprot id: A0A6P5BRL0
uniprot id: A0A6P5BRL8
uniprot id: A0A6P5BRN8
names: Similarity
messages: Belongs to the phospholipase D family.

9915:LOC109564575
gene id: 9915:LOC109564575
uniprot id: A0A6P5CCY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Putative odorant or sperm cell receptor.

9915:CXCR6
gene id: 9915:CXCR6
uniprot id: A0A6P5DS26
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

9915:RCAN3
gene id: 9915:RCAN3
uniprot id: A0A6P5DF13
names: Similarity
messages: Belongs to the RCAN family.

9915:TMEM30A
gene id: 9915:TMEM30A
uniprot id: A0A6P5CAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

9915:FICD
gene id: 9915:FICD
uniprot id: A0A6P5D568
uniprot id: A0A6P5D716
names: Similarity
messages: Belongs to the fic family.

9915:LOC109567151
gene id: 9915:LOC109567151
uniprot id: A0A6P5CMZ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

9915:LOC109554892
gene id: 9915:LOC109554892
uniprot id: A0A6P5B269
names: Subcellular Location Annotation
messages: Cytoplasm

9915:LOC109554207
gene id: 9915:LOC109554207
uniprot id: A0A6P5AZX7
names: Similarity
messages: Belongs to the peptidase A1 family.

9915:FXYD7
gene id: 9915:FXYD7
uniprot id: A0A6P5DBB3
names: Similarity
messages: Belongs to the FXYD family.

9915:FAM193B
gene id: 9915:FAM193B
uniprot id: A0A6P5C3V8
uniprot id: A0A6P5C3W2
uniprot id: A0A6P5C3Z2
uniprot id: A0A6P5C404
uniprot id: A0A6P5C409
uniprot id: A0A6P5C494
uniprot id: A0A6P5C499
uniprot id: A0A6P5C599
names: Similarity
messages: Belongs to the FAM193 family.

9915:HOGA1
gene id: 9915:HOGA1
uniprot id: A0A6P5ANE4
uniprot id: A0A6P5BGM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.