985008:EL144 RS05425
gene id: 985008:EL144_RS05425
uniprot id: A0A3S4Q541
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

985008:EL144 RS04520
gene id: 985008:EL144_RS04520
uniprot id: A0A3S4PSM4
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

985008:EL144 RS04955
gene id: 985008:EL144_RS04955
uniprot id: A0A448F8C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TPP enzyme family. MenD subfamily.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
messages: Homodimer.

985008:EL144 RS05590
gene id: 985008:EL144_RS05590
uniprot id: A0A448F8S8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

985008:EL144 RS09310
gene id: 985008:EL144_RS09310
uniprot id: A0A448FAT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

985008:EL144 RS02765
gene id: 985008:EL144_RS02765
uniprot id: A0A448F775
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

985008:EL144 RS10785
gene id: 985008:EL144_RS10785
uniprot id: A0A3S4QTB4
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

985008:EL144 RS01365
gene id: 985008:EL144_RS01365
uniprot id: A0A448F6E8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

985008:EL144 RS04465
gene id: 985008:EL144_RS04465
uniprot id: A0A3S4TZF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

985008:EL144 RS09550
gene id: 985008:EL144_RS09550
uniprot id: A0A3S4QT11
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.

985008:EL144 RS08265
gene id: 985008:EL144_RS08265
uniprot id: A0A3S4PZA6
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD.
messages: Belongs to the RecD family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

985008:EL144 RS04680
gene id: 985008:EL144_RS04680
uniprot id: A0A3S4QAW2
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

985008:EL144 RS11010
gene id: 985008:EL144_RS11010
uniprot id: A0A3S4PUM0
names: Function
names: Similarity
messages: Belongs to the Dus family. DusB subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

985008:EL144 RS06040
gene id: 985008:EL144_RS06040
uniprot id: A0A3S4PYM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS04240
gene id: 985008:EL144_RS04240
uniprot id: A0A448F8J8
names: Similarity
messages: Belongs to the threonine synthase family.

985008:EL144 RS08600
gene id: 985008:EL144_RS08600
uniprot id: A0A3S4PZE9
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07275
gene id: 985008:EL144_RS07275
uniprot id: A0A3S5ECU3
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

985008:EL144 RS06495
gene id: 985008:EL144_RS06495
uniprot id: A0A3S4S449
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

985008:EL144 RS09540
gene id: 985008:EL144_RS09540
uniprot id: A0A3S4S514
names: Similarity
messages: Belongs to the HypE family.

985008:EL144 RS07760
gene id: 985008:EL144_RS07760
uniprot id: A0A3S4PZ64
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

985008:EL144 RS04970
gene id: 985008:EL144_RS04970
uniprot id: A0A3S4QRN7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: Multifunctional regulator of fatty acid metabolism.

985008:EL144 RS01270
gene id: 985008:EL144_RS01270
uniprot id: A0A3S4QQJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

985008:EL144 RS04785
gene id: 985008:EL144_RS04785
uniprot id: A0A448F879
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

985008:EL144 RS05900
gene id: 985008:EL144_RS05900
uniprot id: A0A3S4TZU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
messages: Cytoplasm
messages: Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.

985008:EL144 RS11135
gene id: 985008:EL144_RS11135
uniprot id: A0A3S4TRW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsX family.
messages: Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
messages: Cytoplasm
messages: Homodimer. Probably interacts with PlsY.

985008:EL144 RS10395
gene id: 985008:EL144_RS10395
uniprot id: A0A3S4PZY0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

985008:EL144 RS03790
gene id: 985008:EL144_RS03790
uniprot id: A0A448F8B1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

985008:EL144 RS09580
gene id: 985008:EL144_RS09580
uniprot id: A0A448FAV1
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
messages: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine.

985008:EL144 RS10030
gene id: 985008:EL144_RS10030
uniprot id: A0A3S4TRK6
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

985008:EL144 RS09000
gene id: 985008:EL144_RS09000
uniprot id: A0A3S4Q689
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.

985008:EL144 RS02970
gene id: 985008:EL144_RS02970
uniprot id: A0A3S4Q4B6
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

985008:EL144 RS06670
gene id: 985008:EL144_RS06670
uniprot id: A0A3S4RI04
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

985008:EL144 RS05545
gene id: 985008:EL144_RS05545
uniprot id: A0A448F8M9
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

985008:EL144 RS08215
gene id: 985008:EL144_RS08215
uniprot id: A0A448FAA9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThiI family.
messages: Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS09720
gene id: 985008:EL144_RS09720
uniprot id: A0A3S4U0Z6
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

985008:EL144 RS05650
gene id: 985008:EL144_RS05650
uniprot id: A0A3S4PT00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

985008:EL144 RS10860
gene id: 985008:EL144_RS10860
uniprot id: A0A3S4QTC0
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

985008:EL144 RS04215
gene id: 985008:EL144_RS04215
uniprot id: A0A3S4Q4Q2
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

985008:EL144 RS02945
gene id: 985008:EL144_RS02945
uniprot id: A0A448F7N2
names: Subcellular Location Annotation
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS00495
gene id: 985008:EL144_RS00495
uniprot id: A0A448F5Y7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Cell membrane
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

985008:EL144 RS07315
gene id: 985008:EL144_RS07315
uniprot id: A0A448F9P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS02925
gene id: 985008:EL144_RS02925
uniprot id: A0A3S4TZ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS06725
gene id: 985008:EL144_RS06725
uniprot id: A0A3S4PYV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

985008:EL144 RS10615
gene id: 985008:EL144_RS10615
uniprot id: A0A448FBD9
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

985008:EL144 RS09835
gene id: 985008:EL144_RS09835
uniprot id: A0A3S4U110
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

985008:EL144 RS08090
gene id: 985008:EL144_RS08090
uniprot id: A0A3S4RIE0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

985008:EL144 RS04995
gene id: 985008:EL144_RS04995
uniprot id: A0A3S4PY98
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Probably interacts with PlsX.

985008:EL144 RS04230
gene id: 985008:EL144_RS04230
uniprot id: A0A3S4RH97
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
messages: Cytoplasm

985008:EL144 RS03240
gene id: 985008:EL144_RS03240
uniprot id: A0A448F7L4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

985008:EL144 RS03645
gene id: 985008:EL144_RS03645
uniprot id: A0A3S4PSC6
names: Similarity
messages: Belongs to the NadC/ModD family.

985008:EL144 RS02915
gene id: 985008:EL144_RS02915
uniprot id: A0A3S4PS61
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

985008:EL144 RS06695
gene id: 985008:EL144_RS06695
uniprot id: A0A3S4QS75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

985008:EL144 RS10390
gene id: 985008:EL144_RS10390
uniprot id: A0A3S4Q6M5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

985008:EL144 RS05930
gene id: 985008:EL144_RS05930
uniprot id: A0A448F8Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

985008:EL144 RS05800
gene id: 985008:EL144_RS05800
uniprot id: A0A448F9A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

985008:EL144 RS05055
gene id: 985008:EL144_RS05055
uniprot id: A0A3S5ECS0
names: Function
names: Similarity
messages: Belongs to the ribF family.
messages: Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD.

985008:EL144 RS03485
gene id: 985008:EL144_RS03485
uniprot id: A0A3S4TPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolB family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer.
messages: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein.

985008:EL144 RS09955
gene id: 985008:EL144_RS09955
uniprot id: A0A448FBI9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

985008:EL144 RS00710
gene id: 985008:EL144_RS00710
uniprot id: A0A3S4PRK2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

985008:EL144 RS02395
gene id: 985008:EL144_RS02395
uniprot id: A0A448F7E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

985008:EL144 RS00845
gene id: 985008:EL144_RS00845
uniprot id: A0A3S4RGD1
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

985008:EL144 RS11000
gene id: 985008:EL144_RS11000
uniprot id: A0A3S4S5H6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

985008:EL144 RS09870
gene id: 985008:EL144_RS09870
uniprot id: A0A448FB59
names: Cofactor
names: Similarity
messages: Belongs to the RimK family.
messages: Binds 2 magnesium or manganese ions per subunit.

985008:EL144 RS04450
gene id: 985008:EL144_RS04450
uniprot id: A0A3S4PSL3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

985008:EL144 RS00770
gene id: 985008:EL144_RS00770
uniprot id: A0A448F6E4
names: Similarity
messages: Belongs to the bacterial solute-binding protein 1 family.

985008:EL144 RS01155
gene id: 985008:EL144_RS01155
uniprot id: A0A3S4RGG4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.

985008:EL144 RS01860
gene id: 985008:EL144_RS01860
uniprot id: A0A448F6Q6
names: Similarity
messages: Belongs to the UPF0225 family.

985008:EL144 RS00445
gene id: 985008:EL144_RS00445
uniprot id: A0A3S4PWX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

985008:EL144 RS03225
gene id: 985008:EL144_RS03225
uniprot id: A0A448F7V5
names: Function
names: Similarity
messages: Belongs to the flavodoxin family.
messages: Low-potential electron donor to a number of redox enzymes.

985008:EL144 RS10050
gene id: 985008:EL144_RS10050
uniprot id: A0A448FBN1
names: Similarity
messages: Belongs to the YciI family.

985008:EL144 RS00760
gene id: 985008:EL144_RS00760
uniprot id: A0A3S4RGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HflD family.
messages: Cell membrane
messages: Cytoplasm

985008:EL144 RS08115
gene id: 985008:EL144_RS08115
uniprot id: A0A3S4U0F9
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS10130
gene id: 985008:EL144_RS10130
uniprot id: A0A448FB56
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily.
messages: Homodimer.
messages: With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P.

985008:EL144 RS00515
gene id: 985008:EL144_RS00515
uniprot id: A0A3S4Q3M7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

985008:EL144 RS07100
gene id: 985008:EL144_RS07100
uniprot id: A0A3S4U054
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS09130
gene id: 985008:EL144_RS09130
uniprot id: A0A3S4S4X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhD family.
messages: Cytoplasm
messages: Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH.

985008:EL144 RS11120
gene id: 985008:EL144_RS11120
uniprot id: A0A3S4Q6V7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

985008:EL144 RS06155
gene id: 985008:EL144_RS06155
uniprot id: A0A448F8Y8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

985008:EL144 RS03200
gene id: 985008:EL144_RS03200
uniprot id: A0A3S4QAI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

985008:EL144 RS05120
gene id: 985008:EL144_RS05120
uniprot id: A0A3S4S3R7
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS01925
gene id: 985008:EL144_RS01925
uniprot id: A0A448F741
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

985008:EL144 RS07405
gene id: 985008:EL144_RS07405
uniprot id: A0A3S4Q5R5
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

985008:EL144 RS08245
gene id: 985008:EL144_RS08245
uniprot id: A0A448FAM0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05010
gene id: 985008:EL144_RS05010
uniprot id: A0A3S4QAZ7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

985008:EL144 RS02390
gene id: 985008:EL144_RS02390
uniprot id: A0A3S4PXI8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05440
gene id: 985008:EL144_RS05440
uniprot id: A0A448F8P9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

985008:EL144 RS08605
gene id: 985008:EL144_RS08605
uniprot id: A0A448FAI8
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05255
gene id: 985008:EL144_RS05255
uniprot id: A0A3S4RHK8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

985008:EL144 RS02795
gene id: 985008:EL144_RS02795
uniprot id: A0A448F787
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08360
gene id: 985008:EL144_RS08360
uniprot id: A0A448FAS6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10380
gene id: 985008:EL144_RS10380
uniprot id: A0A448FBF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS09780
gene id: 985008:EL144_RS09780
uniprot id: A0A448FAZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

985008:EL144 RS09260
gene id: 985008:EL144_RS09260
uniprot id: A0A3S4PZM0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

985008:EL144 RS09775
gene id: 985008:EL144_RS09775
uniprot id: A0A3S4QCD5
names: Subcellular Location Annotation
messages: Cell surface

985008:EL144 RS07220
gene id: 985008:EL144_RS07220
uniprot id: A0A448F9H5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

985008:EL144 RS04110
gene id: 985008:EL144_RS04110
uniprot id: A0A3S4QRD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

985008:EL144 RS04165
gene id: 985008:EL144_RS04165
uniprot id: A0A448F7Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS05645
gene id: 985008:EL144_RS05645
uniprot id: A0A448F971
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

985008:EL144 RS09280
gene id: 985008:EL144_RS09280
uniprot id: A0A3S4RIR2
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08110
gene id: 985008:EL144_RS08110
uniprot id: A0A3S4QSN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Binds AI-2 and delivers it to the LsrC and LsrD permeases.
messages: Periplasm
messages: The complex is composed of two ATP-binding proteins (LsrA), two transmembrane proteins (LsrC and LsrD) and a solute-binding protein (LsrB).

985008:EL144 RS08770
gene id: 985008:EL144_RS08770
uniprot id: A0A3S4Q662
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

985008:EL144 RS02890
gene id: 985008:EL144_RS02890
uniprot id: A0A3S4S2Z6
names: Similarity
messages: Belongs to the peptidase S41A family.

985008:EL144 RS06570
gene id: 985008:EL144_RS06570
uniprot id: A0A3S4Q5G0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapD family.
messages: Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin-arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export.
messages: Cytoplasm
messages: Interacts with the cytoplasmic NapA precursor.

985008:EL144 RS03270
gene id: 985008:EL144_RS03270
uniprot id: A0A448F7W7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

985008:EL144 RS05980
gene id: 985008:EL144_RS05980
uniprot id: A0A448F8Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraB family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome.
messages: Interacts with the C-terminal region of Rne.

985008:EL144 RS06675
gene id: 985008:EL144_RS06675
uniprot id: A0A3S4QBG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

985008:EL144 RS10505
gene id: 985008:EL144_RS10505
uniprot id: A0A3S4RJ08
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

985008:EL144 RS07870
gene id: 985008:EL144_RS07870
uniprot id: A0A3S4RIC4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05235
gene id: 985008:EL144_RS05235
uniprot id: A0A3S4PYD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GlpE family.
messages: Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide.
messages: Cytoplasm

985008:EL144 RS03765
gene id: 985008:EL144_RS03765
uniprot id: A0A448F7R4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CitD family.
messages: Covalent carrier of the coenzyme of citrate lyase.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.

985008:EL144 RS00625
gene id: 985008:EL144_RS00625
uniprot id: A0A3S4QQB0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Cytoplasm
messages: Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
messages: Monomer.

985008:EL144 RS02375
gene id: 985008:EL144_RS02375
uniprot id: A0A3S5ECP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

985008:EL144 RS00510
gene id: 985008:EL144_RS00510
uniprot id: A0A3S5ECM3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

985008:EL144 RS00715
gene id: 985008:EL144_RS00715
uniprot id: A0A3S4QQC0
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

985008:EL144 RS04410
gene id: 985008:EL144_RS04410
uniprot id: A0A448F848
names: Function
messages: Acts as a radical domain for damaged PFL and possibly other radical proteins.

985008:EL144 RS03140
gene id: 985008:EL144_RS03140
uniprot id: A0A3S5ECQ0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

985008:EL144 RS02920
gene id: 985008:EL144_RS02920
uniprot id: A0A3S4QR11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS06665
gene id: 985008:EL144_RS06665
uniprot id: A0A3S4TQM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

985008:EL144 RS05340
gene id: 985008:EL144_RS05340
uniprot id: A0A448F8I9
names: Similarity
messages: Belongs to the UPF0149 family.

985008:EL144 RS06925
gene id: 985008:EL144_RS06925
uniprot id: A0A3S4RI34
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

985008:EL144 RS00225
gene id: 985008:EL144_RS00225
uniprot id: A0A448F5S7
names: Similarity
messages: Belongs to the P(II) protein family.

985008:EL144 RS07095
gene id: 985008:EL144_RS07095
uniprot id: A0A448F9M2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

985008:EL144 RS10735
gene id: 985008:EL144_RS10735
uniprot id: A0A3S4Q014
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

985008:EL144 RS08400
gene id: 985008:EL144_RS08400
uniprot id: A0A3S4TR46
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

985008:EL144 RS08475
gene id: 985008:EL144_RS08475
uniprot id: A0A3S4Q633
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

985008:EL144 RS01880
gene id: 985008:EL144_RS01880
uniprot id: A0A3S4TYQ9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS09635
gene id: 985008:EL144_RS09635
uniprot id: A0A3S4PU83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family.
messages: Cell membrane
messages: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites.
messages: Membrane

985008:EL144 RS03895
gene id: 985008:EL144_RS03895
uniprot id: A0A448F7V6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Binds 2 magnesium or manganese ions per subunit.
messages: Cell wall formation.
messages: Cytoplasm

985008:EL144 RS05970
gene id: 985008:EL144_RS05970
uniprot id: A0A3S4PT32
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

985008:EL144 RS00565
gene id: 985008:EL144_RS00565
uniprot id: A0A448F6F2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

985008:EL144 RS06070
gene id: 985008:EL144_RS06070
uniprot id: A0A3S4QBA4
names: Similarity
messages: Belongs to the ClpA/ClpB family.

985008:EL144 RS05745
gene id: 985008:EL144_RS05745
uniprot id: A0A448F996
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

985008:EL144 RS01890
gene id: 985008:EL144_RS01890
uniprot id: A0A448F779
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

985008:EL144 RS10220
gene id: 985008:EL144_RS10220
uniprot id: A0A3S4PUE4
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

985008:EL144 RS08695
gene id: 985008:EL144_RS08695
uniprot id: A0A3S4TR72
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

985008:EL144 RS07960
gene id: 985008:EL144_RS07960
uniprot id: A0A3S4U0E3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

985008:EL144 RS08650
gene id: 985008:EL144_RS08650
uniprot id: A0A3S4S4S1
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07565
gene id: 985008:EL144_RS07565
uniprot id: A0A448F9V2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

985008:EL144 RS02180
gene id: 985008:EL144_RS02180
uniprot id: A0A448F771
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS01040
gene id: 985008:EL144_RS01040
uniprot id: A0A3S5ECM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS05985
gene id: 985008:EL144_RS05985
uniprot id: A0A3S4QS01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

985008:EL144 RS00870
gene id: 985008:EL144_RS00870
uniprot id: A0A448F6I4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of sn-l,2-diacylglycerol (DAG) to phosphatidic acid. Involved in the recycling of diacylglycerol produced as a by-product during membrane-derived oligosaccharide (MDO) biosynthesis.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS04835
gene id: 985008:EL144_RS04835
uniprot id: A0A448F8D5
names: Similarity
messages: Belongs to the YfgM family.

985008:EL144 RS06915
gene id: 985008:EL144_RS06915
uniprot id: A0A3S4TQR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS07050
gene id: 985008:EL144_RS07050
uniprot id: A0A448F9K0
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

985008:EL144 RS02505
gene id: 985008:EL144_RS02505
uniprot id: A0A448F773
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

985008:EL144 RS08405
gene id: 985008:EL144_RS08405
uniprot id: A0A448FA75
names: Similarity
messages: Belongs to the UPF0263 family.

985008:EL144 RS04210
gene id: 985008:EL144_RS04210
uniprot id: A0A3S5ECR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamC family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

985008:EL144 RS05725
gene id: 985008:EL144_RS05725
uniprot id: A0A448F8T7
names: Function
names: Similarity
messages: Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
messages: Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.

985008:EL144 RS07090
gene id: 985008:EL144_RS07090
uniprot id: A0A448FA21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

985008:EL144 RS06910
gene id: 985008:EL144_RS06910
uniprot id: A0A3S4PYX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS05835
gene id: 985008:EL144_RS05835
uniprot id: A0A3S4Q584
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

985008:EL144 RS07365
gene id: 985008:EL144_RS07365
uniprot id: A0A448F9Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

985008:EL144 RS10805
gene id: 985008:EL144_RS10805
uniprot id: A0A448FBK3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptC family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptA and the LptBFG transporter complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA.
messages: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

985008:EL144 RS04205
gene id: 985008:EL144_RS04205
uniprot id: A0A448F844
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

985008:EL144 RS08160
gene id: 985008:EL144_RS08160
uniprot id: A0A448FA23
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

985008:EL144 RS06600
gene id: 985008:EL144_RS06600
uniprot id: A0A3S4QBF6
names: Similarity
messages: In the C-terminal section; belongs to the glutathionylspermidine synthase preATP-grasp family.

985008:EL144 RS08010
gene id: 985008:EL144_RS08010
uniprot id: A0A448FA62
names: Similarity
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase small subunit family.
messages: Heterodimer of a large and a small subunit.

985008:EL144 RS01225
gene id: 985008:EL144_RS01225
uniprot id: A0A3S4TP57
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS01115
gene id: 985008:EL144_RS01115
uniprot id: A0A448F6B5
names: Subunit
messages: Monomer.

985008:EL144 RS04375
gene id: 985008:EL144_RS04375
uniprot id: A0A3S4Q4S2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

985008:EL144 RS01015
gene id: 985008:EL144_RS01015
uniprot id: A0A3S4PRN9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

985008:EL144 RS00335
gene id: 985008:EL144_RS00335
uniprot id: A0A448F619
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10145
gene id: 985008:EL144_RS10145
uniprot id: A0A448FB46
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
messages: Belongs to the FrdC family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

985008:EL144 RS07280
gene id: 985008:EL144_RS07280
uniprot id: A0A3S4Q5Q1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 3 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

985008:EL144 RS00320
gene id: 985008:EL144_RS00320
uniprot id: A0A3S4QQ81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

985008:EL144 RS02960
gene id: 985008:EL144_RS02960
uniprot id: A0A448F7T8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

985008:EL144 RS09665
gene id: 985008:EL144_RS09665
uniprot id: A0A3S5ECW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS02730
gene id: 985008:EL144_RS02730
uniprot id: A0A3S5ECP6
names: Subcellular Location Annotation
messages: Cell surface

985008:EL144 RS00765
gene id: 985008:EL144_RS00765
uniprot id: A0A3S4Q9W9
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

985008:EL144 RS06720
gene id: 985008:EL144_RS06720
uniprot id: A0A3S4Q5I3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

985008:EL144 RS05330
gene id: 985008:EL144_RS05330
uniprot id: A0A448F953
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

985008:EL144 RS04040
gene id: 985008:EL144_RS04040
uniprot id: A0A448F8F9
names: Similarity
messages: Belongs to the peptidase A24 family.

985008:EL144 RS04950
gene id: 985008:EL144_RS04950
uniprot id: A0A3S4S3P0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MenH family.
messages: Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC).
messages: Monomer.

985008:EL144 RS05145
gene id: 985008:EL144_RS05145
uniprot id: A0A3S4TZM1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

985008:EL144 RS10135
gene id: 985008:EL144_RS10135
uniprot id: A0A3S4U135
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

985008:EL144 RS08910
gene id: 985008:EL144_RS08910
uniprot id: A0A3S4U0P4
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

985008:EL144 RS00505
gene id: 985008:EL144_RS00505
uniprot id: A0A3S4TYC3
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

985008:EL144 RS00665
gene id: 985008:EL144_RS00665
uniprot id: A0A3S4PWZ5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

985008:EL144 RS08145
gene id: 985008:EL144_RS08145
uniprot id: A0A448FAM7
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

985008:EL144 RS08775
gene id: 985008:EL144_RS08775
uniprot id: A0A3S4PZG8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

985008:EL144 RS08440
gene id: 985008:EL144_RS08440
uniprot id: A0A3S4S4Q6
names: Similarity
messages: Belongs to the peptidase S13 family.

985008:EL144 RS10945
gene id: 985008:EL144_RS10945
uniprot id: A0A3S4U1B8
names: Similarity
messages: Belongs to the peptidase A24 family.

985008:EL144 RS04005
gene id: 985008:EL144_RS04005
uniprot id: A0A3S4PSG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

985008:EL144 RS03135
gene id: 985008:EL144_RS03135
uniprot id: A0A3S4TZ26
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

985008:EL144 RS09160
gene id: 985008:EL144_RS09160
uniprot id: A0A3S5ECW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

985008:EL144 RS04255
gene id: 985008:EL144_RS04255
uniprot id: A0A448F855
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

985008:EL144 RS03900
gene id: 985008:EL144_RS03900
uniprot id: A0A3S4S396
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

985008:EL144 RS00450
gene id: 985008:EL144_RS00450
uniprot id: A0A3S4TNX2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

985008:EL144 RS00805
gene id: 985008:EL144_RS00805
uniprot id: A0A3S5ECM6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

985008:EL144 RS07735
gene id: 985008:EL144_RS07735
uniprot id: A0A3S4QSI8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
messages: Homotetramer.
messages: Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.

985008:EL144 RS06055
gene id: 985008:EL144_RS06055
uniprot id: A0A3S4TQH4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

985008:EL144 RS01525
gene id: 985008:EL144_RS01525
uniprot id: A0A3S4TP81
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

985008:EL144 RS05080
gene id: 985008:EL144_RS05080
uniprot id: A0A3S4TQ68
names: Similarity
messages: Belongs to the UPF0234 family.

985008:EL144 RS11045
gene id: 985008:EL144_RS11045
uniprot id: A0A3S4RJ52
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

985008:EL144 RS09460
gene id: 985008:EL144_RS09460
uniprot id: A0A448FAU5
names: Similarity
messages: Belongs to the peptidase A31 family.

985008:EL144 RS02510
gene id: 985008:EL144_RS02510
uniprot id: A0A3S4QQX0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

985008:EL144 RS09770
gene id: 985008:EL144_RS09770
uniprot id: A0A3S4RIV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

985008:EL144 RS10185
gene id: 985008:EL144_RS10185
uniprot id: A0A3S4RIY2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

985008:EL144 RS02800
gene id: 985008:EL144_RS02800
uniprot id: A0A3S4S2Y5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

985008:EL144 RS04845
gene id: 985008:EL144_RS04845
uniprot id: A0A3S4TQ40
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

985008:EL144 RS05215
gene id: 985008:EL144_RS05215
uniprot id: A0A448F8Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS07910
gene id: 985008:EL144_RS07910
uniprot id: A0A3S4S4J8
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08205
gene id: 985008:EL144_RS08205
uniprot id: A0A448FAN1
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TorC/TorY family.
messages: Binds 5 heme groups per subunit.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS05675
gene id: 985008:EL144_RS05675
uniprot id: A0A448F8S5
names: Similarity
messages: Belongs to the Nudix hydrolase family.

985008:EL144 RS07860
gene id: 985008:EL144_RS07860
uniprot id: A0A3S4TR02
names: Similarity
messages: Belongs to the peptidase M1 family.

985008:EL144 RS03935
gene id: 985008:EL144_RS03935
uniprot id: A0A448F8A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

985008:EL144 RS09175
gene id: 985008:EL144_RS09175
uniprot id: A0A3S4PZL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 5DNU family.
messages: Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS10095
gene id: 985008:EL144_RS10095
uniprot id: A0A448FB93
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

985008:EL144 RS03635
gene id: 985008:EL144_RS03635
uniprot id: A0A448F800
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

985008:EL144 RS04935
gene id: 985008:EL144_RS04935
uniprot id: A0A448F8B2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SprT family.
messages: Binds 1 zinc ion.
messages: Cytoplasm

985008:EL144 RS03535
gene id: 985008:EL144_RS03535
uniprot id: A0A448F7X6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Cell inner membrane
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

985008:EL144 RS06280
gene id: 985008:EL144_RS06280
uniprot id: A0A448F978
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

985008:EL144 RS10410
gene id: 985008:EL144_RS10410
uniprot id: A0A448FBV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

985008:EL144 RS01900
gene id: 985008:EL144_RS01900
uniprot id: A0A448F6Q3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS00405
gene id: 985008:EL144_RS00405
uniprot id: A0A448F690
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family. YidE subfamily.
messages: Cell membrane

985008:EL144 RS03015
gene id: 985008:EL144_RS03015
uniprot id: A0A448F7Q0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07595
gene id: 985008:EL144_RS07595
uniprot id: A0A448FAB9
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

985008:EL144 RS05690
gene id: 985008:EL144_RS05690
uniprot id: A0A3S4Q573
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LptE lipoprotein family.
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.
messages: Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.

985008:EL144 RS09315
gene id: 985008:EL144_RS09315
uniprot id: A0A448FAS9
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

985008:EL144 RS04605
gene id: 985008:EL144_RS04605
uniprot id: A0A448F8M2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05115
gene id: 985008:EL144_RS05115
uniprot id: A0A3S4QB06
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
messages: Interacts with FtsZ via their C-terminal domains.

985008:EL144 RS09875
gene id: 985008:EL144_RS09875
uniprot id: A0A3S4S558
names: Similarity
messages: Belongs to the flavin oxidoreductase frp family.

985008:EL144 RS07580
gene id: 985008:EL144_RS07580
uniprot id: A0A448FA79
names: Similarity
messages: Belongs to the fructosamine kinase family.

985008:EL144 RS08005
gene id: 985008:EL144_RS08005
uniprot id: A0A3S4QBV5
names: Function
names: Similarity
messages: Belongs to the TrpC family.
messages: Belongs to the TrpF family.
messages: Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
messages: In the C-terminal section; belongs to the TrpF family.
messages: In the N-terminal section; belongs to the TrpC family.

985008:EL144 RS06225
gene id: 985008:EL144_RS06225
uniprot id: A0A3S5ECT2
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

985008:EL144 RS05500
gene id: 985008:EL144_RS05500
uniprot id: A0A3S4Q551
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

985008:EL144 RS08130
gene id: 985008:EL144_RS08130
uniprot id: A0A3S4PZA0
names: Similarity
messages: Belongs to the SorC transcriptional regulatory family.

985008:EL144 RS03305
gene id: 985008:EL144_RS03305
uniprot id: A0A448F7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AzlC family.
messages: Membrane

985008:EL144 RS05250
gene id: 985008:EL144_RS05250
uniprot id: A0A448F8K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family. TsaC subfamily.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.

985008:EL144 RS08025
gene id: 985008:EL144_RS08025
uniprot id: A0A448F9Y3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
messages: Cell membrane
messages: Heterodimer of a large and a small subunit.

985008:EL144 RS03870
gene id: 985008:EL144_RS03870
uniprot id: A0A448F7T6
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

985008:EL144 RS04225
gene id: 985008:EL144_RS04225
uniprot id: A0A3S4TPY4
names: Similarity
names: Subunit
messages: Homotetramer.
messages: In the C-terminal section; belongs to the homoserine dehydrogenase family.
messages: In the N-terminal section; belongs to the aspartokinase family.

985008:EL144 RS03845
gene id: 985008:EL144_RS03845
uniprot id: A0A3S5ECQ7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

985008:EL144 RS11115
gene id: 985008:EL144_RS11115
uniprot id: A0A3S5ECY3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

985008:EL144 RS04975
gene id: 985008:EL144_RS04975
uniprot id: A0A3S4TZK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaB Na(+)/H(+) (TC 2.A.34) antiporter family.
messages: Cell membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

985008:EL144 RS10770
gene id: 985008:EL144_RS10770
uniprot id: A0A448FBL8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

985008:EL144 RS04445
gene id: 985008:EL144_RS04445
uniprot id: A0A3S4S3G1
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

985008:EL144 RS00180
gene id: 985008:EL144_RS00180
uniprot id: A0A448F5S4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

985008:EL144 RS03195
gene id: 985008:EL144_RS03195
uniprot id: A0A3S4RGZ3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

985008:EL144 RS04425
gene id: 985008:EL144_RS04425
uniprot id: A0A3S4QAU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

985008:EL144 RS01750
gene id: 985008:EL144_RS01750
uniprot id: A0A3S4PRV8
names: Similarity
messages: Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

985008:EL144 RS08920
gene id: 985008:EL144_RS08920
uniprot id: A0A3S4Q680
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Gram-negative porin family.
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS10100
gene id: 985008:EL144_RS10100
uniprot id: A0A3S4PUD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

985008:EL144 RS02075
gene id: 985008:EL144_RS02075
uniprot id: A0A3S4TYS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
messages: Interacts with the RNAP. Has a higher affinity for the core RNAP than for the holoenzyme. Its ATPase activity is stimulated by binding to RNAP.
messages: Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair.

985008:EL144 RS02275
gene id: 985008:EL144_RS02275
uniprot id: A0A3S5ECP2
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.
messages: Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.
messages: Homodimer.
messages: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

985008:EL144 RS10045
gene id: 985008:EL144_RS10045
uniprot id: A0A3S4QCF5
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

985008:EL144 RS00370
gene id: 985008:EL144_RS00370
uniprot id: A0A3S4Q3L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamA family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

985008:EL144 RS03510
gene id: 985008:EL144_RS03510
uniprot id: A0A3S4PSB4
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05320
gene id: 985008:EL144_RS05320
uniprot id: A0A448F8Z1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

985008:EL144 RS05585
gene id: 985008:EL144_RS05585
uniprot id: A0A448F9A3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS01825
gene id: 985008:EL144_RS01825
uniprot id: A0A3S4RGM5
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

985008:EL144 RS07310
gene id: 985008:EL144_RS07310
uniprot id: A0A448F9Q2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

985008:EL144 RS08270
gene id: 985008:EL144_RS08270
uniprot id: A0A448FA43
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

985008:EL144 RS00500
gene id: 985008:EL144_RS00500
uniprot id: A0A3S4QQ97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

985008:EL144 RS03530
gene id: 985008:EL144_RS03530
uniprot id: A0A3S4TZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptF/LptG family.
messages: Component of the lipopolysaccharide transport and assembly complex. The LptBFG transporter is composed of two ATP-binding proteins (LptB) and two transmembrane proteins (LptF and LptG).
messages: Membrane
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane.

985008:EL144 RS10270
gene id: 985008:EL144_RS10270
uniprot id: A0A3S5ECX4
names: Similarity
messages: Belongs to the GARS family.

985008:EL144 RS07120
gene id: 985008:EL144_RS07120
uniprot id: A0A3S4PZ00
names: Subcellular Location Annotation
messages: Cell inner membrane

985008:EL144 RS05820
gene id: 985008:EL144_RS05820
uniprot id: A0A448F8Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS03540
gene id: 985008:EL144_RS03540
uniprot id: A0A448F822
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

985008:EL144 RS05775
gene id: 985008:EL144_RS05775
uniprot id: A0A3S4TZT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

985008:EL144 RS10780
gene id: 985008:EL144_RS10780
uniprot id: A0A448FC09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

985008:EL144 RS07145
gene id: 985008:EL144_RS07145
uniprot id: A0A448F9N7
names: Function
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family. NagK subfamily.
messages: Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P.

985008:EL144 RS03455
gene id: 985008:EL144_RS03455
uniprot id: A0A3S4TZ53
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

985008:EL144 RS05785
gene id: 985008:EL144_RS05785
uniprot id: A0A448F8R8
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS05880
gene id: 985008:EL144_RS05880
uniprot id: A0A448F8X1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

985008:EL144 RS03250
gene id: 985008:EL144_RS03250
uniprot id: A0A448F7G7
names: Similarity
messages: Belongs to the SUI1 family.

985008:EL144 RS10020
gene id: 985008:EL144_RS10020
uniprot id: A0A448FB92
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

985008:EL144 RS02785
gene id: 985008:EL144_RS02785
uniprot id: A0A3S4QAE6
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

985008:EL144 RS02150
gene id: 985008:EL144_RS02150
uniprot id: A0A3S4TYT6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

985008:EL144 RS06705
gene id: 985008:EL144_RS06705
uniprot id: A0A448F9V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapB family.
messages: Cytoplasm
messages: Homodimer. The ends of the coiled-coil dimer bind to each other, forming polymers. Interacts with FtsZ.
messages: Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA.

985008:EL144 RS06730
gene id: 985008:EL144_RS06730
uniprot id: A0A3S4TQN7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

985008:EL144 RS08255
gene id: 985008:EL144_RS08255
uniprot id: A0A3S4Q603
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

985008:EL144 RS00670
gene id: 985008:EL144_RS00670
uniprot id: A0A3S4TNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

985008:EL144 RS04115
gene id: 985008:EL144_RS04115
uniprot id: A0A3S4TZB6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

985008:EL144 RS06945
gene id: 985008:EL144_RS06945
uniprot id: A0A3S4PTE4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

985008:EL144 RS08435
gene id: 985008:EL144_RS08435
uniprot id: A0A448FAQ1
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

985008:EL144 RS09625
gene id: 985008:EL144_RS09625
uniprot id: A0A3S4QCB5
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

985008:EL144 RS09735
gene id: 985008:EL144_RS09735
uniprot id: A0A3S4Q6G4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.

985008:EL144 RS09375
gene id: 985008:EL144_RS09375
uniprot id: A0A448FAU2
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

985008:EL144 RS10660
gene id: 985008:EL144_RS10660
uniprot id: A0A448FC28
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS00525
gene id: 985008:EL144_RS00525
uniprot id: A0A448F608
names: Similarity
messages: Belongs to the DprA/Smf family.

985008:EL144 RS05265
gene id: 985008:EL144_RS05265
uniprot id: A0A3S4S3T1
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS08000
gene id: 985008:EL144_RS08000
uniprot id: A0A3S4RID0
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07285
gene id: 985008:EL144_RS07285
uniprot id: A0A448FA51
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

985008:EL144 RS08235
gene id: 985008:EL144_RS08235
uniprot id: A0A448FA81
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

985008:EL144 RS05015
gene id: 985008:EL144_RS05015
uniprot id: A0A448F8S9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

985008:EL144 RS00435
gene id: 985008:EL144_RS00435
uniprot id: A0A3S5ECM2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

985008:EL144 RS08030
gene id: 985008:EL144_RS08030
uniprot id: A0A448FAH1
names: Similarity
messages: Belongs to the peptidase A31 family.

985008:EL144 RS03045
gene id: 985008:EL144_RS03045
uniprot id: A0A3S4PS71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

985008:EL144 RS11165
gene id: 985008:EL144_RS11165
uniprot id: A0A448FC70
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

985008:EL144 RS09700
gene id: 985008:EL144_RS09700
uniprot id: A0A448FBJ6
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

985008:EL144 RS09990
gene id: 985008:EL144_RS09990
uniprot id: A0A3S4QT50
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.
messages: The complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

985008:EL144 RS03630
gene id: 985008:EL144_RS03630
uniprot id: A0A448F837
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

985008:EL144 RS05385
gene id: 985008:EL144_RS05385
uniprot id: A0A3S4QRU3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

985008:EL144 RS07975
gene id: 985008:EL144_RS07975
uniprot id: A0A448F9X1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

985008:EL144 RS08735
gene id: 985008:EL144_RS08735
uniprot id: A0A3S4PTZ3
names: Similarity
messages: Belongs to the SfsA family.

985008:EL144 RS07515
gene id: 985008:EL144_RS07515
uniprot id: A0A448F9U0
names: Caution
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07190
gene id: 985008:EL144_RS07190
uniprot id: A0A3S5ECU2
names: Similarity
messages: Belongs to the UDP-galactopyranose/dTDP-fucopyranose mutase family.

985008:EL144 RS06435
gene id: 985008:EL144_RS06435
uniprot id: A0A448F9B0
names: Similarity
messages: Belongs to the SlyX family.

985008:EL144 RS07210
gene id: 985008:EL144_RS07210
uniprot id: A0A448F9M9
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

985008:EL144 RS03440
gene id: 985008:EL144_RS03440
uniprot id: A0A448F7Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LolA family.
messages: Monomer.
messages: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
messages: Periplasm

985008:EL144 RS03825
gene id: 985008:EL144_RS03825
uniprot id: A0A3S4PSE9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

985008:EL144 RS01440
gene id: 985008:EL144_RS01440
uniprot id: A0A448F6H0
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: In the N-terminal section; belongs to the histidinol-phosphatase family.

985008:EL144 RS02720
gene id: 985008:EL144_RS02720
uniprot id: A0A448F762
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

985008:EL144 RS03495
gene id: 985008:EL144_RS03495
uniprot id: A0A3S4RH24
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

985008:EL144 RS10600
gene id: 985008:EL144_RS10600
uniprot id: A0A3S4QCK0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation. Within the RNA degradosome, RNase E assembles into a homotetramer formed by a dimer of dimers.
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.

985008:EL144 RS06690
gene id: 985008:EL144_RS06690
uniprot id: A0A3S4PTA6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

985008:EL144 RS09825
gene id: 985008:EL144_RS09825
uniprot id: A0A448FB18
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

985008:EL144 RS04185
gene id: 985008:EL144_RS04185
uniprot id: A0A448F8F3
names: Similarity
messages: Belongs to the glutamine synthetase family.

985008:EL144 RS02225
gene id: 985008:EL144_RS02225
uniprot id: A0A448F7A1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmJ family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the guanosine in position 1516 of 16S rRNA.

985008:EL144 RS00905
gene id: 985008:EL144_RS00905
uniprot id: A0A3S4PX27
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homodimer.
messages: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II ManXYZ PTS system is involved in mannose transport.

985008:EL144 RS06575
gene id: 985008:EL144_RS06575
uniprot id: A0A3S4PYS6
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.
messages: Binds 1 [4Fe-4S] cluster.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

985008:EL144 RS00575
gene id: 985008:EL144_RS00575
uniprot id: A0A448F618
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell inner membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

985008:EL144 RS00200
gene id: 985008:EL144_RS00200
uniprot id: A0A3S4PRF4
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

985008:EL144 RS09505
gene id: 985008:EL144_RS09505
uniprot id: A0A448FAZ0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10165
gene id: 985008:EL144_RS10165
uniprot id: A0A448FBU9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

985008:EL144 RS09680
gene id: 985008:EL144_RS09680
uniprot id: A0A448FB06
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

985008:EL144 RS07025
gene id: 985008:EL144_RS07025
uniprot id: A0A448F9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0283 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane

985008:EL144 RS00910
gene id: 985008:EL144_RS00910
uniprot id: A0A448F674
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS03070
gene id: 985008:EL144_RS03070
uniprot id: A0A3S4TZ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS08865
gene id: 985008:EL144_RS08865
uniprot id: A0A3S4TR89
names: Similarity
messages: Belongs to the peptidase C40 family.

985008:EL144 RS03385
gene id: 985008:EL144_RS03385
uniprot id: A0A3S4Q4G0
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

985008:EL144 RS09385
gene id: 985008:EL144_RS09385
uniprot id: A0A448FBA7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ADP transfer from ATP to D-glycero-beta-D-manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose.
messages: Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate at the C-1 position to selectively form D-glycero-beta-D-manno-heptose-1,7-bisphosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the cytidylyltransferase family.
messages: In the N-terminal section; belongs to the carbohydrate kinase PfkB family.

985008:EL144 RS07395
gene id: 985008:EL144_RS07395
uniprot id: A0A448F9U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
messages: Forms an icosahedral capsid composed of 60 subunits, arranged as a dodecamer of pentamers.

985008:EL144 RS10750
gene id: 985008:EL144_RS10750
uniprot id: A0A3S4RJ25
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

985008:EL144 RS06460
gene id: 985008:EL144_RS06460
uniprot id: A0A3S4TNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

985008:EL144 RS03780
gene id: 985008:EL144_RS03780
uniprot id: A0A448F829
names: Similarity
messages: Belongs to the CitG/MdcB family.

985008:EL144 RS09490
gene id: 985008:EL144_RS09490
uniprot id: A0A3S4Q6D5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS03695
gene id: 985008:EL144_RS03695
uniprot id: A0A448F890
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

985008:EL144 RS08575
gene id: 985008:EL144_RS08575
uniprot id: A0A3S4U0L1
names: Activity Regulation
names: Function
names: Similarity
names: Subunit
messages: Activated by ATP and maltotriose, which are both required for DNA binding.
messages: Belongs to the MalT family.
messages: Monomer in solution. Oligomerizes to an active state in the presence of the positive effectors ATP and maltotriose.
messages: Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Specifically binds to the promoter region of its target genes, recognizing a short DNA motif called the MalT box.

985008:EL144 RS04270
gene id: 985008:EL144_RS04270
uniprot id: A0A448F805
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09195
gene id: 985008:EL144_RS09195
uniprot id: A0A448FAP8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily.
messages: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS00460
gene id: 985008:EL144_RS00460
uniprot id: A0A448F679
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane
messages: Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins.

985008:EL144 RS07410
gene id: 985008:EL144_RS07410
uniprot id: A0A448F9S4
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

985008:EL144 RS05825
gene id: 985008:EL144_RS05825
uniprot id: A0A448F8W5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

985008:EL144 RS10665
gene id: 985008:EL144_RS10665
uniprot id: A0A3S4QTA6
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

985008:EL144 RS03280
gene id: 985008:EL144_RS03280
uniprot id: A0A448F7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

985008:EL144 RS00360
gene id: 985008:EL144_RS00360
uniprot id: A0A448F657
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

985008:EL144 RS10055
gene id: 985008:EL144_RS10055
uniprot id: A0A448FBL0
names: Similarity
messages: Belongs to the transglycosylase Slt family.

985008:EL144 RS10180
gene id: 985008:EL144_RS10180
uniprot id: A0A448FB66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YajC family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the SecDF-YidC-YajC translocase complex. The SecDF-YidC-YajC translocase forms a supercomplex with SecYEG, called the holo-translocon (HTL).
messages: The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions.

985008:EL144 RS07650
gene id: 985008:EL144_RS07650
uniprot id: A0A448FAD5
names: Function
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.
messages: Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives.

985008:EL144 RS05410
gene id: 985008:EL144_RS05410
uniprot id: A0A448F8M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Cell inner membrane
messages: Mediates influx of magnesium ions (By similarity). Alternates between open and closed states. Activated by low cytoplasmic Mg(2+) levels. Inactive when cytoplasmic Mg(2+) levels are high.
messages: Membrane

985008:EL144 RS04160
gene id: 985008:EL144_RS04160
uniprot id: A0A3S4S3C7
names: Similarity
messages: Belongs to the UPF0381 family.

985008:EL144 RS01400
gene id: 985008:EL144_RS01400
uniprot id: A0A3S4QQK5
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the PRA-PH family.
messages: In the N-terminal section; belongs to the PRA-CH family.

985008:EL144 RS08460
gene id: 985008:EL144_RS08460
uniprot id: A0A3S4QSS0
names: Similarity
messages: Belongs to the UPF0276 family.

985008:EL144 RS06300
gene id: 985008:EL144_RS06300
uniprot id: A0A448F961
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

985008:EL144 RS10535
gene id: 985008:EL144_RS10535
uniprot id: A0A3S4QT99
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

985008:EL144 RS07775
gene id: 985008:EL144_RS07775
uniprot id: A0A448F9T5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukF family.
messages: Interacts, and probably forms a ternary complex, with MukE and MukB via its C-terminal region. The complex formation is stimulated by calcium or magnesium. It is required for an interaction between MukE and MukB.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
messages: nucleoid

985008:EL144 RS11075
gene id: 985008:EL144_RS11075
uniprot id: A0A448FCC0
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

985008:EL144 RS02630
gene id: 985008:EL144_RS02630
uniprot id: A0A3S4S2W7
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

985008:EL144 RS00865
gene id: 985008:EL144_RS00865
uniprot id: A0A3S4PRL9
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

985008:EL144 RS07385
gene id: 985008:EL144_RS07385
uniprot id: A0A448FA72
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

985008:EL144 RS10675
gene id: 985008:EL144_RS10675
uniprot id: A0A448FBK6
names: Function
messages: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division.

985008:EL144 RS10965
gene id: 985008:EL144_RS10965
uniprot id: A0A3S4Q6T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS10090
gene id: 985008:EL144_RS10090
uniprot id: A0A448FB75
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Binds two Mg(2+) per subunit.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

985008:EL144 RS09595
gene id: 985008:EL144_RS09595
uniprot id: A0A448FBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

985008:EL144 RS10065
gene id: 985008:EL144_RS10065
uniprot id: A0A448FBS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

985008:EL144 RS09645
gene id: 985008:EL144_RS09645
uniprot id: A0A448FBC8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS10375
gene id: 985008:EL144_RS10375
uniprot id: A0A448FBZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

985008:EL144 RS03470
gene id: 985008:EL144_RS03470
uniprot id: A0A3S4Q4H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

985008:EL144 RS08645
gene id: 985008:EL144_RS08645
uniprot id: A0A448FB02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DksA family.
messages: Cytoplasm
messages: Interacts directly with the RNA polymerase.
messages: Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression.

985008:EL144 RS03435
gene id: 985008:EL144_RS03435
uniprot id: A0A3S4S343
names: Function
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.
messages: DNA-dependent ATPase that plays important roles in cellular responses to stalled DNA replication processes.

985008:EL144 RS03975
gene id: 985008:EL144_RS03975
uniprot id: A0A3S4RH72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

985008:EL144 RS08240
gene id: 985008:EL144_RS08240
uniprot id: A0A448FA24
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS06930
gene id: 985008:EL144_RS06930
uniprot id: A0A3S4QBJ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecX family.
messages: Cytoplasm
messages: Modulates RecA activity.

985008:EL144 RS02370
gene id: 985008:EL144_RS02370
uniprot id: A0A448F708
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LuxS family.
messages: Binds 1 Fe cation per subunit.
messages: Homodimer.
messages: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD).

985008:EL144 RS05525
gene id: 985008:EL144_RS05525
uniprot id: A0A3S4S3X0
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

985008:EL144 RS01395
gene id: 985008:EL144_RS01395
uniprot id: A0A448F6G0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NfuA family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is presumably bound at the interface of two monomers.
messages: Homodimer.
messages: Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.

985008:EL144 RS04960
gene id: 985008:EL144_RS04960
uniprot id: A0A3S4PSR4
names: Function
names: Similarity
messages: Belongs to the isochorismate synthase family.
messages: Catalyzes the conversion of chorismate to isochorismate.

985008:EL144 RS00165
gene id: 985008:EL144_RS00165
uniprot id: A0A3S4PWU4
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

985008:EL144 RS09715
gene id: 985008:EL144_RS09715
uniprot id: A0A3S4QT25
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

985008:EL144 RS04580
gene id: 985008:EL144_RS04580
uniprot id: A0A448F836
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS01340
gene id: 985008:EL144_RS01340
uniprot id: A0A448F6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

985008:EL144 RS02550
gene id: 985008:EL144_RS02550
uniprot id: A0A3S4Q471
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

985008:EL144 RS08080
gene id: 985008:EL144_RS08080
uniprot id: A0A448F9Z3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

985008:EL144 RS10000
gene id: 985008:EL144_RS10000
uniprot id: A0A3S5ECX2
names: Subcellular Location Annotation
messages: Cell inner membrane

985008:EL144 RS00965
gene id: 985008:EL144_RS00965
uniprot id: A0A3S5ECM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS06765
gene id: 985008:EL144_RS06765
uniprot id: A0A448F9B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

985008:EL144 RS10245
gene id: 985008:EL144_RS10245
uniprot id: A0A3S4U146
names: Function
names: Similarity
messages: Belongs to the IolE/MocC family.
messages: Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol).

985008:EL144 RS08510
gene id: 985008:EL144_RS08510
uniprot id: A0A3S4RII8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

985008:EL144 RS03020
gene id: 985008:EL144_RS03020
uniprot id: A0A3S4TPL4
names: Similarity
messages: Belongs to the UPF0339 family. Duplicated subfamily.

985008:EL144 RS01135
gene id: 985008:EL144_RS01135
uniprot id: A0A3S4PX56
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

985008:EL144 RS07560
gene id: 985008:EL144_RS07560
uniprot id: A0A3S4PZ40
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

985008:EL144 RS04690
gene id: 985008:EL144_RS04690
uniprot id: A0A448F8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmF/CycK/Ccl1/NrfE/CcsA family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS06645
gene id: 985008:EL144_RS06645
uniprot id: A0A448F9R7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

985008:EL144 RS00535
gene id: 985008:EL144_RS00535
uniprot id: A0A448F661
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

985008:EL144 RS03770
gene id: 985008:EL144_RS03770
uniprot id: A0A448F7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HpcH/HpaI aldolase family. Citrate lyase beta subunit subfamily.
messages: Cytoplasm
messages: Oligomer with a subunit composition of (alpha,beta,gamma)6.
messages: Represents a citryl-ACP lyase.

985008:EL144 RS06045
gene id: 985008:EL144_RS06045
uniprot id: A0A448F911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS05005
gene id: 985008:EL144_RS05005
uniprot id: A0A3S4RHH9
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08915
gene id: 985008:EL144_RS08915
uniprot id: A0A3S5ECW0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

985008:EL144 RS09935
gene id: 985008:EL144_RS09935
uniprot id: A0A3S4TRK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS10815
gene id: 985008:EL144_RS10815
uniprot id: A0A448FBL2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the ABC transporter complex MlaFEDB, which is involved in a phospholipid transport pathway that maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MlaF), two transmembrane proteins (MlaE), two cytoplasmic solute-binding proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).

985008:EL144 RS04770
gene id: 985008:EL144_RS04770
uniprot id: A0A448F8R4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS06880
gene id: 985008:EL144_RS06880
uniprot id: A0A3S4U032
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.
messages: Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.

985008:EL144 RS03465
gene id: 985008:EL144_RS03465
uniprot id: A0A3S5ECQ3
names: Similarity
messages: Belongs to the UPF0111 family.

985008:EL144 RS02040
gene id: 985008:EL144_RS02040
uniprot id: A0A448F778
names: Function
names: Subunit
messages: Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins.
messages: Homodimer.

985008:EL144 RS07570
gene id: 985008:EL144_RS07570
uniprot id: A0A3S4TQW8
names: Similarity
messages: Belongs to the peptidase S49 family.

985008:EL144 RS05045
gene id: 985008:EL144_RS05045
uniprot id: A0A3S4QRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

985008:EL144 RS08800
gene id: 985008:EL144_RS08800
uniprot id: A0A3S4QC41
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

985008:EL144 RS04000
gene id: 985008:EL144_RS04000
uniprot id: A0A3S4S3A7
names: Similarity
messages: Belongs to the Gfa family.

985008:EL144 RS11105
gene id: 985008:EL144_RS11105
uniprot id: A0A3S4U1D6
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS11130
gene id: 985008:EL144_RS11130
uniprot id: A0A3S4Q061
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

985008:EL144 RS07710
gene id: 985008:EL144_RS07710
uniprot id: A0A448F9Z6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

985008:EL144 RS00955
gene id: 985008:EL144_RS00955
uniprot id: A0A3S4TYH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS04335
gene id: 985008:EL144_RS04335
uniprot id: A0A3S4S3E7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsP family.
messages: Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress.
messages: Periplasm

985008:EL144 RS05805
gene id: 985008:EL144_RS05805
uniprot id: A0A448F9D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

985008:EL144 RS09890
gene id: 985008:EL144_RS09890
uniprot id: A0A448FB49
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS04010
gene id: 985008:EL144_RS04010
uniprot id: A0A448F7X2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TmcA family.
messages: Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: nucleolus

985008:EL144 RS10200
gene id: 985008:EL144_RS10200
uniprot id: A0A448FBR2
names: Similarity
messages: In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
messages: In the N-terminal section; belongs to the aldehyde dehydrogenase family.

985008:EL144 RS04485
gene id: 985008:EL144_RS04485
uniprot id: A0A3S4TQ10
names: Function
names: Similarity
names: Subunit
messages: A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis.
messages: Belongs to the YihI family.
messages: Interacts with Der.

985008:EL144 RS06310
gene id: 985008:EL144_RS06310
uniprot id: A0A3S4TZX9
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

985008:EL144 RS04635
gene id: 985008:EL144_RS04635
uniprot id: A0A3S4Q4U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

985008:EL144 RS10690
gene id: 985008:EL144_RS10690
uniprot id: A0A448FBJ2
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

985008:EL144 RS04325
gene id: 985008:EL144_RS04325
uniprot id: A0A448F8H3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxH family.
messages: Binds 2 Mn(2+) ions per subunit in a binuclear metal center.
messages: Cell inner membrane
messages: Hydrolyzes the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

985008:EL144 RS02625
gene id: 985008:EL144_RS02625
uniprot id: A0A448F7H0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

985008:EL144 RS09725
gene id: 985008:EL144_RS09725
uniprot id: A0A448FAZ8
names: Function
names: Similarity
messages: Belongs to the IscX family.
messages: May function as iron donor in the assembly of iron-sulfur clusters.

985008:EL144 RS09685
gene id: 985008:EL144_RS09685
uniprot id: A0A3S4TRH3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS05315
gene id: 985008:EL144_RS05315
uniprot id: A0A3S4PYD9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.
messages: Belongs to the RimM family.
messages: Binds ribosomal protein S19.
messages: Cytoplasm
messages: The PRC barrel domain binds ribosomal protein S19.

985008:EL144 RS08780
gene id: 985008:EL144_RS08780
uniprot id: A0A3S4TR83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

985008:EL144 RS03995
gene id: 985008:EL144_RS03995
uniprot id: A0A3S4QAQ4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

985008:EL144 RS06005
gene id: 985008:EL144_RS06005
uniprot id: A0A448F9H8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

985008:EL144 RS07745
gene id: 985008:EL144_RS07745
uniprot id: A0A3S5ECU7
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

985008:EL144 RS04430
gene id: 985008:EL144_RS04430
uniprot id: A0A448F8G9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS07265
gene id: 985008:EL144_RS07265
uniprot id: A0A3S4QSE8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

985008:EL144 RS03915
gene id: 985008:EL144_RS03915
uniprot id: A0A3S4QRB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

985008:EL144 RS06030
gene id: 985008:EL144_RS06030
uniprot id: A0A448F920
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

985008:EL144 RS08290
gene id: 985008:EL144_RS08290
uniprot id: A0A3S4RIF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thioester dehydratase family. FabA subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length.

985008:EL144 RS09995
gene id: 985008:EL144_RS09995
uniprot id: A0A3S4U126
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS00540
gene id: 985008:EL144_RS00540
uniprot id: A0A448F5Y6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

985008:EL144 RS03005
gene id: 985008:EL144_RS03005
uniprot id: A0A448F7B5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

985008:EL144 RS00430
gene id: 985008:EL144_RS00430
uniprot id: A0A3S4TYB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

985008:EL144 RS10085
gene id: 985008:EL144_RS10085
uniprot id: A0A3S4S589
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS03920
gene id: 985008:EL144_RS03920
uniprot id: A0A448F7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

985008:EL144 RS00675
gene id: 985008:EL144_RS00675
uniprot id: A0A3S4RGB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

985008:EL144 RS09265
gene id: 985008:EL144_RS09265
uniprot id: A0A448FAQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

985008:EL144 RS03940
gene id: 985008:EL144_RS03940
uniprot id: A0A3S4Q4M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

985008:EL144 RS06885
gene id: 985008:EL144_RS06885
uniprot id: A0A3S5ECT9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS10280
gene id: 985008:EL144_RS10280
uniprot id: A0A448FB85
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09170
gene id: 985008:EL144_RS09170
uniprot id: A0A448FB40
names: Similarity
messages: Belongs to the ModE family.

985008:EL144 RS05285
gene id: 985008:EL144_RS05285
uniprot id: A0A3S4TZP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

985008:EL144 RS11155
gene id: 985008:EL144_RS11155
uniprot id: A0A448FBN7
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

985008:EL144 RS04050
gene id: 985008:EL144_RS04050
uniprot id: A0A448F7T5
names: Similarity
messages: Belongs to the bacterial secretin family.

985008:EL144 RS10465
gene id: 985008:EL144_RS10465
uniprot id: A0A3S4U167
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase T family.
messages: Binds two Mg(2+) per subunit. The active form of the enzyme binds two Mg(2+) ions in its active site. The first Mg(2+) forms only one salt bridge with the protein.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.

985008:EL144 RS11070
gene id: 985008:EL144_RS11070
uniprot id: A0A448FCA4
names: Function
names: Similarity
messages: Belongs to the peptidase S11 family.
messages: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.

985008:EL144 RS10425
gene id: 985008:EL144_RS10425
uniprot id: A0A3S4QCI6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS00930
gene id: 985008:EL144_RS00930
uniprot id: A0A3S4Q9Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

985008:EL144 RS00730
gene id: 985008:EL144_RS00730
uniprot id: A0A3S5ECM5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07550
gene id: 985008:EL144_RS07550
uniprot id: A0A3S4Q5S6
names: Activity Regulation
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.

985008:EL144 RS01855
gene id: 985008:EL144_RS01855
uniprot id: A0A448F6U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS01505
gene id: 985008:EL144_RS01505
uniprot id: A0A3S4Q3Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

985008:EL144 RS07520
gene id: 985008:EL144_RS07520
uniprot id: A0A448F9N9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

985008:EL144 RS00600
gene id: 985008:EL144_RS00600
uniprot id: A0A448F617
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-1 family.
messages: Cytoplasm

985008:EL144 RS04075
gene id: 985008:EL144_RS04075
uniprot id: A0A3S4TPW4
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS04695
gene id: 985008:EL144_RS04695
uniprot id: A0A448F8A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

985008:EL144 RS09250
gene id: 985008:EL144_RS09250
uniprot id: A0A3S5ECW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RnfG family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS00465
gene id: 985008:EL144_RS00465
uniprot id: A0A3S4Q9U2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Cell membrane
messages: Involved in the TonB-dependent energy-dependent transport of various receptor-bound substrates.
messages: Membrane
messages: The accessory proteins ExbB and ExbD seem to form a complex with TonB.

985008:EL144 RS00580
gene id: 985008:EL144_RS00580
uniprot id: A0A448F615
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

985008:EL144 RS05105
gene id: 985008:EL144_RS05105
uniprot id: A0A448F8D8
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

985008:EL144 RS07635
gene id: 985008:EL144_RS07635
uniprot id: A0A3S4U099
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

985008:EL144 RS03835
gene id: 985008:EL144_RS03835
uniprot id: A0A448F872
names: Function
names: Similarity
messages: Acts on ADP-mannose and ADP-glucose as well as ADP-ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process.
messages: Belongs to the Nudix hydrolase family. NudF subfamily.

985008:EL144 RS10015
gene id: 985008:EL144_RS10015
uniprot id: A0A448FBR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS03185
gene id: 985008:EL144_RS03185
uniprot id: A0A448F7G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS06590
gene id: 985008:EL144_RS06590
uniprot id: A0A3S4TQL9
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NapB family.
messages: Binds 2 heme C groups per subunit.
messages: Component of the periplasmic nitrate reductase NapAB complex composed of NapA and NapB.
messages: Electron transfer subunit of the periplasmic nitrate reductase complex NapAB.
messages: Periplasm

985008:EL144 RS05830
gene id: 985008:EL144_RS05830
uniprot id: A0A448F8W0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

985008:EL144 RS09650
gene id: 985008:EL144_RS09650
uniprot id: A0A3S4U0Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

985008:EL144 RS03160
gene id: 985008:EL144_RS03160
uniprot id: A0A3S4Q4D9
names: Similarity
messages: Belongs to the RutC family.

985008:EL144 RS11110
gene id: 985008:EL144_RS11110
uniprot id: A0A448FC73
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS04630
gene id: 985008:EL144_RS04630
uniprot id: A0A448F889
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

985008:EL144 RS10300
gene id: 985008:EL144_RS10300
uniprot id: A0A448FBT4
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

985008:EL144 RS08740
gene id: 985008:EL144_RS08740
uniprot id: A0A3S4QST6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS05475
gene id: 985008:EL144_RS05475
uniprot id: A0A3S4PSX5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS06180
gene id: 985008:EL144_RS06180
uniprot id: A0A3S4S422
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

985008:EL144 RS09590
gene id: 985008:EL144_RS09590
uniprot id: A0A3S4TRG3
names: Similarity
messages: Belongs to the RecJ family.

985008:EL144 RS09765
gene id: 985008:EL144_RS09765
uniprot id: A0A448FBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

985008:EL144 RS10005
gene id: 985008:EL144_RS10005
uniprot id: A0A3S4Q6J5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

985008:EL144 RS01475
gene id: 985008:EL144_RS01475
uniprot id: A0A3S4QQL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Membrane

985008:EL144 RS00790
gene id: 985008:EL144_RS00790
uniprot id: A0A3S4QQD3
names: Function
names: Similarity
messages: Belongs to the Dus family. DusC subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs.

985008:EL144 RS07840
gene id: 985008:EL144_RS07840
uniprot id: A0A448FAG3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

985008:EL144 RS07950
gene id: 985008:EL144_RS07950
uniprot id: A0A448F9Y8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

985008:EL144 RS07420
gene id: 985008:EL144_RS07420
uniprot id: A0A3S4PZ31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

985008:EL144 RS03910
gene id: 985008:EL144_RS03910
uniprot id: A0A448F7U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

985008:EL144 RS02660
gene id: 985008:EL144_RS02660
uniprot id: A0A448F765
names: Function
names: Similarity
messages: Belongs to the NanE family.
messages: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P).

985008:EL144 RS03130
gene id: 985008:EL144_RS03130
uniprot id: A0A448F7X3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07480
gene id: 985008:EL144_RS07480
uniprot id: A0A448FA58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS00485
gene id: 985008:EL144_RS00485
uniprot id: A0A448F651
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

985008:EL144 RS04685
gene id: 985008:EL144_RS04685
uniprot id: A0A3S4S3L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

985008:EL144 RS00350
gene id: 985008:EL144_RS00350
uniprot id: A0A3S5ECM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

985008:EL144 RS10240
gene id: 985008:EL144_RS10240
uniprot id: A0A448FBC6
names: Similarity
messages: Belongs to the TPP enzyme family.

985008:EL144 RS10155
gene id: 985008:EL144_RS10155
uniprot id: A0A3S4Q6K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

985008:EL144 RS07740
gene id: 985008:EL144_RS07740
uniprot id: A0A3S4U0B8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

985008:EL144 RS03655
gene id: 985008:EL144_RS03655
uniprot id: A0A3S4TZ69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS05135
gene id: 985008:EL144_RS05135
uniprot id: A0A448F8E8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

985008:EL144 RS10010
gene id: 985008:EL144_RS10010
uniprot id: A0A448FBQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

985008:EL144 RS08170
gene id: 985008:EL144_RS08170
uniprot id: A0A3S4S4M5
names: Similarity
messages: Belongs to the MoaD family.

985008:EL144 RS05730
gene id: 985008:EL144_RS05730
uniprot id: A0A3S4QB73
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

985008:EL144 RS08765
gene id: 985008:EL144_RS08765
uniprot id: A0A448FAI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

985008:EL144 RS00185
gene id: 985008:EL144_RS00185
uniprot id: A0A3S4Q9S3
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

985008:EL144 RS07630
gene id: 985008:EL144_RS07630
uniprot id: A0A448F9Q9
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

985008:EL144 RS07930
gene id: 985008:EL144_RS07930
uniprot id: A0A448FAF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

985008:EL144 RS08760
gene id: 985008:EL144_RS08760
uniprot id: A0A3S5ECV8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

985008:EL144 RS05040
gene id: 985008:EL144_RS05040
uniprot id: A0A3S4PSS3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

985008:EL144 RS02190
gene id: 985008:EL144_RS02190
uniprot id: A0A3S4TPE7
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS04825
gene id: 985008:EL144_RS04825
uniprot id: A0A3S5ECR7
names: Similarity
messages: Belongs to the DnaA family.

985008:EL144 RS01035
gene id: 985008:EL144_RS01035
uniprot id: A0A3S4TYI2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07440
gene id: 985008:EL144_RS07440
uniprot id: A0A448FA85
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

985008:EL144 RS06510
gene id: 985008:EL144_RS06510
uniprot id: A0A448F965
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

985008:EL144 RS02610
gene id: 985008:EL144_RS02610
uniprot id: A0A448F755
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

985008:EL144 RS02770
gene id: 985008:EL144_RS02770
uniprot id: A0A448F772
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxine kinase family. PdxY subfamily.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.

985008:EL144 RS06285
gene id: 985008:EL144_RS06285
uniprot id: A0A448F923
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

985008:EL144 RS06485
gene id: 985008:EL144_RS06485
uniprot id: A0A448F9M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic pantothenate kinase family.
messages: Cytoplasm

985008:EL144 RS04070
gene id: 985008:EL144_RS04070
uniprot id: A0A3S4PY04
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS01335
gene id: 985008:EL144_RS01335
uniprot id: A0A3S4PX79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfur carrier protein TusA family.
messages: Cytoplasm
messages: Sulfur carrier protein which probably makes part of a sulfur-relay system.

985008:EL144 RS05150
gene id: 985008:EL144_RS05150
uniprot id: A0A3S5ECS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

985008:EL144 RS03080
gene id: 985008:EL144_RS03080
uniprot id: A0A448F7W3
names: Similarity
messages: Belongs to the UPF0319 family.

985008:EL144 RS02210
gene id: 985008:EL144_RS02210
uniprot id: A0A448F6X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

985008:EL144 RS03100
gene id: 985008:EL144_RS03100
uniprot id: A0A448F7F5
names: Similarity
messages: Belongs to the UPF0115 family.

985008:EL144 RS06840
gene id: 985008:EL144_RS06840
uniprot id: A0A448F9U4
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07795
gene id: 985008:EL144_RS07795
uniprot id: A0A3S4PTP6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family. MukB subfamily.
messages: Homodimerization via its hinge domain. Binds to DNA via its C-terminal region. Interacts, and probably forms a ternary complex, with MukE and MukF via its C-terminal region. The complex formation is stimulated by calcium or magnesium. Interacts with tubulin-related protein FtsZ.
messages: Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division.
messages: The hinge domain, which separates the large intramolecular coiled coil regions, allows the homodimerization, forming a V-shaped homodimer.
messages: nucleoid

985008:EL144 RS10745
gene id: 985008:EL144_RS10745
uniprot id: A0A3S4TRR7
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

985008:EL144 RS09500
gene id: 985008:EL144_RS09500
uniprot id: A0A3S4PZP1
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS01845
gene id: 985008:EL144_RS01845
uniprot id: A0A448F6Q2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

985008:EL144 RS10755
gene id: 985008:EL144_RS10755
uniprot id: A0A3S4QCL2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

985008:EL144 RS04830
gene id: 985008:EL144_RS04830
uniprot id: A0A3S4Q4W5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10510
gene id: 985008:EL144_RS10510
uniprot id: A0A448FBG0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

985008:EL144 RS07445
gene id: 985008:EL144_RS07445
uniprot id: A0A3S4QBQ0
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

985008:EL144 RS03860
gene id: 985008:EL144_RS03860
uniprot id: A0A448F7X4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

985008:EL144 RS10275
gene id: 985008:EL144_RS10275
uniprot id: A0A448FBB9
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

985008:EL144 RS00660
gene id: 985008:EL144_RS00660
uniprot id: A0A448F6B6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

985008:EL144 RS07430
gene id: 985008:EL144_RS07430
uniprot id: A0A3S4RI79
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS04065
gene id: 985008:EL144_RS04065
uniprot id: A0A3S4Q4N2
names: Similarity
messages: Belongs to the GSP E family.

985008:EL144 RS04170
gene id: 985008:EL144_RS04170
uniprot id: A0A448F7Y4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

985008:EL144 RS00475
gene id: 985008:EL144_RS00475
uniprot id: A0A3S4S2B1
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07380
gene id: 985008:EL144_RS07380
uniprot id: A0A448FA37
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.

985008:EL144 RS03170
gene id: 985008:EL144_RS03170
uniprot id: A0A448F7P6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

985008:EL144 RS00985
gene id: 985008:EL144_RS00985
uniprot id: A0A448F6R7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS04625
gene id: 985008:EL144_RS04625
uniprot id: A0A3S5ECR5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

985008:EL144 RS07805
gene id: 985008:EL144_RS07805
uniprot id: A0A448F9V5
names: Cofactor
messages: Binds 2 Mg(2+) ions per monomer.

985008:EL144 RS09435
gene id: 985008:EL144_RS09435
uniprot id: A0A3S4QCA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS02940
gene id: 985008:EL144_RS02940
uniprot id: A0A448F7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.
messages: Cytoplasm
messages: Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.

985008:EL144 RS11050
gene id: 985008:EL144_RS11050
uniprot id: A0A448FBT2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS10620
gene id: 985008:EL144_RS10620
uniprot id: A0A448FBI0
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

985008:EL144 RS02280
gene id: 985008:EL144_RS02280
uniprot id: A0A448F790
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

985008:EL144 RS04570
gene id: 985008:EL144_RS04570
uniprot id: A0A3S4QRJ2
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

985008:EL144 RS01420
gene id: 985008:EL144_RS01420
uniprot id: A0A448F6U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

985008:EL144 RS01150
gene id: 985008:EL144_RS01150
uniprot id: A0A448F6C1
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

985008:EL144 RS10190
gene id: 985008:EL144_RS10190
uniprot id: A0A448FBB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

985008:EL144 RS05050
gene id: 985008:EL144_RS05050
uniprot id: A0A3S4TZL1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

985008:EL144 RS11025
gene id: 985008:EL144_RS11025
uniprot id: A0A3S5ECY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

985008:EL144 RS09790
gene id: 985008:EL144_RS09790
uniprot id: A0A448FB27
names: Similarity
messages: Belongs to the Dps family.

985008:EL144 RS04190
gene id: 985008:EL144_RS04190
uniprot id: A0A3S4PSI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS06990
gene id: 985008:EL144_RS06990
uniprot id: A0A3S4Q5L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS00590
gene id: 985008:EL144_RS00590
uniprot id: A0A3S4Q9V6
names: Function
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.
messages: Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.

985008:EL144 RS10645
gene id: 985008:EL144_RS10645
uniprot id: A0A3S4PUI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

985008:EL144 RS05530
gene id: 985008:EL144_RS05530
uniprot id: A0A448F955
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoid occlusion factor SlmA family.
messages: Homodimer. Interacts with FtsZ.
messages: Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
messages: nucleoid

985008:EL144 RS08295
gene id: 985008:EL144_RS08295
uniprot id: A0A448FA33
names: Similarity
messages: Belongs to the peptidase S16 family.

985008:EL144 RS07955
gene id: 985008:EL144_RS07955
uniprot id: A0A448FA50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

985008:EL144 RS08595
gene id: 985008:EL144_RS08595
uniprot id: A0A3S4Q643
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS08990
gene id: 985008:EL144_RS08990
uniprot id: A0A3S5ECW1
names: Similarity
messages: Belongs to the KAE1 / TsaD family. TsaB subfamily.

985008:EL144 RS04840
gene id: 985008:EL144_RS04840
uniprot id: A0A3S4PY77
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS02155
gene id: 985008:EL144_RS02155
uniprot id: A0A3S5ECP1
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08520
gene id: 985008:EL144_RS08520
uniprot id: A0A3S4S4R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS07980
gene id: 985008:EL144_RS07980
uniprot id: A0A3S4Q5X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate.
messages: Homotetramer.

985008:EL144 RS00820
gene id: 985008:EL144_RS00820
uniprot id: A0A3S4PX15
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS10725
gene id: 985008:EL144_RS10725
uniprot id: A0A3S5ECX8
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

985008:EL144 RS04930
gene id: 985008:EL144_RS04930
uniprot id: A0A448F8F5
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS09210
gene id: 985008:EL144_RS09210
uniprot id: A0A3S4S4Y6
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

985008:EL144 RS08845
gene id: 985008:EL144_RS08845
uniprot id: A0A3S4PZH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system).
messages: Membrane

985008:EL144 RS00980
gene id: 985008:EL144_RS00980
uniprot id: A0A3S4PX35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
messages: Homohexamer; trimer of homodimers.

985008:EL144 RS09545
gene id: 985008:EL144_RS09545
uniprot id: A0A3S4PU76
names: Similarity
messages: Belongs to the HypD family.

985008:EL144 RS02670
gene id: 985008:EL144_RS02670
uniprot id: A0A3S4PXK7
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

985008:EL144 RS06215
gene id: 985008:EL144_RS06215
uniprot id: A0A448F9G7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

985008:EL144 RS06895
gene id: 985008:EL144_RS06895
uniprot id: A0A448F9V1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsB family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

985008:EL144 RS02640
gene id: 985008:EL144_RS02640
uniprot id: A0A3S4QQY1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Allosterically activated by N-acetylglucosamine 6-phosphate (GlcNAc6P).
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05300
gene id: 985008:EL144_RS05300
uniprot id: A0A448F8L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Cell inner membrane
messages: Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins.
messages: Membrane

985008:EL144 RS08140
gene id: 985008:EL144_RS08140
uniprot id: A0A3S4RIF0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07170
gene id: 985008:EL144_RS07170
uniprot id: A0A3S4PTH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gtrA family.
messages: Involved in O antigen modification. Involved in the translocation of bactoprenol-linked glucose across the cytoplasmic membrane.
messages: Membrane

985008:EL144 RS03310
gene id: 985008:EL144_RS03310
uniprot id: A0A448F7W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

985008:EL144 RS06305
gene id: 985008:EL144_RS06305
uniprot id: A0A3S4QS31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

985008:EL144 RS04795
gene id: 985008:EL144_RS04795
uniprot id: A0A3S4PSP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

985008:EL144 RS07645
gene id: 985008:EL144_RS07645
uniprot id: A0A448FAD0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

985008:EL144 RS01185
gene id: 985008:EL144_RS01185
uniprot id: A0A448F6S4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

985008:EL144 RS05755
gene id: 985008:EL144_RS05755
uniprot id: A0A3S4QRY3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

985008:EL144 RS03105
gene id: 985008:EL144_RS03105
uniprot id: A0A3S4RGY1
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily.
messages: Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue.

985008:EL144 RS09610
gene id: 985008:EL144_RS09610
uniprot id: A0A448FB11
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS08075
gene id: 985008:EL144_RS08075
uniprot id: A0A3S4TR15
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

985008:EL144 RS05355
gene id: 985008:EL144_RS05355
uniprot id: A0A3S4QB35
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

985008:EL144 RS01495
gene id: 985008:EL144_RS01495
uniprot id: A0A448F6N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

985008:EL144 RS01430
gene id: 985008:EL144_RS01430
uniprot id: A0A3S4Q3X0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

985008:EL144 RS03985
gene id: 985008:EL144_RS03985
uniprot id: A0A448F864
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS00860
gene id: 985008:EL144_RS00860
uniprot id: A0A3S4S2E9
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA.

985008:EL144 RS01905
gene id: 985008:EL144_RS01905
uniprot id: A0A448F6W4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Divalent metal cations. Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosphate mRNA. The NAD-cap is present at the 5'-end of some mRNAs and stabilizes RNA against 5'-processing. Has preference for mRNAs with a 5'-end purine. Catalyzes the hydrolysis of a broad range of dinucleotide pyrophosphates.

985008:EL144 RS09230
gene id: 985008:EL144_RS09230
uniprot id: A0A448FBA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS01415
gene id: 985008:EL144_RS01415
uniprot id: A0A3S4TYL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

985008:EL144 RS10935
gene id: 985008:EL144_RS10935
uniprot id: A0A3S4QTD0
names: Similarity
messages: Belongs to the GSP E family.

985008:EL144 RS11055
gene id: 985008:EL144_RS11055
uniprot id: A0A3S4QCP8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

985008:EL144 RS10795
gene id: 985008:EL144_RS10795
uniprot id: A0A3S5ECX9
names: Function
names: Similarity
messages: Belongs to the ABC transporter superfamily. Outer membrane lipopolysaccharide export (TC 1.B.42) family.
messages: Part of the ABC transporter complex LptBFG involved in the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. Probably responsible for energy coupling to the transport system.

985008:EL144 RS00130
gene id: 985008:EL144_RS00130
uniprot id: A0A3S4RGM5
names: Similarity
messages: Belongs to the ner transcriptional regulatory family.

985008:EL144 RS06170
gene id: 985008:EL144_RS06170
uniprot id: A0A3S4QBB3
names: Similarity
messages: Belongs to the MlaA family.

985008:EL144 RS02535
gene id: 985008:EL144_RS02535
uniprot id: A0A448F7G6
names: Similarity
messages: Belongs to the UPF0423 family.

985008:EL144 RS06450
gene id: 985008:EL144_RS06450
uniprot id: A0A448F991
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

985008:EL144 RS10215
gene id: 985008:EL144_RS10215
uniprot id: A0A3S4S594
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08190
gene id: 985008:EL144_RS08190
uniprot id: A0A448FAK5
names: Similarity
messages: Belongs to the peptidase S51 family.

985008:EL144 RS06445
gene id: 985008:EL144_RS06445
uniprot id: A0A3S4TQL0
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

985008:EL144 RS07850
gene id: 985008:EL144_RS07850
uniprot id: A0A448F9W6
names: Similarity
messages: Belongs to the peptidase S51 family.

985008:EL144 RS04565
gene id: 985008:EL144_RS04565
uniprot id: A0A448F8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

985008:EL144 RS01945
gene id: 985008:EL144_RS01945
uniprot id: A0A448F6S3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05935
gene id: 985008:EL144_RS05935
uniprot id: A0A3S4TQG3
names: Similarity
messages: Belongs to the ArsC family.

985008:EL144 RS11005
gene id: 985008:EL144_RS11005
uniprot id: A0A448FBK7
names: Function
names: Similarity
names: Subunit
messages: Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters.
messages: Belongs to the transcriptional regulatory Fis family.
messages: Homodimer.

985008:EL144 RS10760
gene id: 985008:EL144_RS10760
uniprot id: A0A448FBF7
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

985008:EL144 RS09190
gene id: 985008:EL144_RS09190
uniprot id: A0A3S4RIQ7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

985008:EL144 RS08705
gene id: 985008:EL144_RS08705
uniprot id: A0A448FAJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS11170
gene id: 985008:EL144_RS11170
uniprot id: A0A3S4QTF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS10685
gene id: 985008:EL144_RS10685
uniprot id: A0A448FBF0
names: Function
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.
messages: Involved in the high-affinity zinc uptake transport system.

985008:EL144 RS10540
gene id: 985008:EL144_RS10540
uniprot id: A0A3S4U177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS09240
gene id: 985008:EL144_RS09240
uniprot id: A0A3S4QSY5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS00160
gene id: 985008:EL144_RS00160
uniprot id: A0A448F5T7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).
messages: Cell membrane
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.

985008:EL144 RS07235
gene id: 985008:EL144_RS07235
uniprot id: A0A3S4QBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S49 family.
messages: Cell inner membrane

985008:EL144 RS04820
gene id: 985008:EL144_RS04820
uniprot id: A0A448F8P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

985008:EL144 RS01010
gene id: 985008:EL144_RS01010
uniprot id: A0A3S4S2H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

985008:EL144 RS10335
gene id: 985008:EL144_RS10335
uniprot id: A0A3S4QCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Pal lipoprotein family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

985008:EL144 RS10120
gene id: 985008:EL144_RS10120
uniprot id: A0A448FBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS07390
gene id: 985008:EL144_RS07390
uniprot id: A0A3S5ECU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

985008:EL144 RS07700
gene id: 985008:EL144_RS07700
uniprot id: A0A448FA10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

985008:EL144 RS02860
gene id: 985008:EL144_RS02860
uniprot id: A0A3S4PXM8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

985008:EL144 RS09050
gene id: 985008:EL144_RS09050
uniprot id: A0A448FAM4
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

985008:EL144 RS03355
gene id: 985008:EL144_RS03355
uniprot id: A0A3S4S336
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

985008:EL144 RS02290
gene id: 985008:EL144_RS02290
uniprot id: A0A448F7F1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the branched chain amino acid transporter family.
messages: Cell inner membrane
messages: Component of the transport system for branched-chain amino acids.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS07790
gene id: 985008:EL144_RS07790
uniprot id: A0A3S4S4J3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MukE family.
messages: Interacts, and probably forms a ternary complex, with MukF and MukB. The complex formation is stimulated by calcium or magnesium.
messages: Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF.
messages: nucleoid

985008:EL144 RS07825
gene id: 985008:EL144_RS07825
uniprot id: A0A3S4PZ74
names: Similarity
messages: Belongs to the universal stress protein A family.

985008:EL144 RS09185
gene id: 985008:EL144_RS09185
uniprot id: A0A448FAT6
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

985008:EL144 RS03830
gene id: 985008:EL144_RS03830
uniprot id: A0A3S4QRA6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.

985008:EL144 RS07720
gene id: 985008:EL144_RS07720
uniprot id: A0A448F9Y5
names: Similarity
messages: Belongs to the disproportionating enzyme family.

985008:EL144 RS06935
gene id: 985008:EL144_RS06935
uniprot id: A0A3S4S4A1
names: Similarity
messages: Belongs to the RutC family.

985008:EL144 RS04280
gene id: 985008:EL144_RS04280
uniprot id: A0A448F8D1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RdgC family.
messages: May be involved in recombination.
messages: nucleoid

985008:EL144 RS00530
gene id: 985008:EL144_RS00530
uniprot id: A0A448F605
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

985008:EL144 RS05715
gene id: 985008:EL144_RS05715
uniprot id: A0A3S4RHR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

985008:EL144 RS04275
gene id: 985008:EL144_RS04275
uniprot id: A0A3S4PSJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

985008:EL144 RS03065
gene id: 985008:EL144_RS03065
uniprot id: A0A448F7R0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS00885
gene id: 985008:EL144_RS00885
uniprot id: A0A3S4TYG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
messages: Cell inner membrane
messages: Forms a membrane-associated complex with FtsE.
messages: Membrane
messages: Part of the ABC transporter FtsEX involved in cellular division.

985008:EL144 RS06820
gene id: 985008:EL144_RS06820
uniprot id: A0A3S4PYW2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E.
messages: Belongs to the RseA family.
messages: Cell inner membrane
messages: Interacts 1:1 with ECF RNA polymerase sigma-E (RpoE); this inhibits the interaction of sigma-E with the RNA polymerase catalytic core and leads to a decreased expression of sigma-E-regulated genes. Interacts with RseB.

985008:EL144 RS04385
gene id: 985008:EL144_RS04385
uniprot id: A0A448F8J5
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homotetramer.

985008:EL144 RS03715
gene id: 985008:EL144_RS03715
uniprot id: A0A3S4RH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

985008:EL144 RS01555
gene id: 985008:EL144_RS01555
uniprot id: A0A3S4PRU0
names: Similarity
messages: Belongs to the UPF0352 family.

985008:EL144 RS06275
gene id: 985008:EL144_RS06275
uniprot id: A0A3S4S431
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSP33 family.
messages: Cytoplasm
messages: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
messages: Under oxidizing conditions two disulfide bonds are formed involving the reactive cysteines. Under reducing conditions zinc is bound to the reactive cysteines and the protein is inactive.

985008:EL144 RS03425
gene id: 985008:EL144_RS03425
uniprot id: A0A448F7J8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS08070
gene id: 985008:EL144_RS08070
uniprot id: A0A3S4PZ92
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

985008:EL144 RS09695
gene id: 985008:EL144_RS09695
uniprot id: A0A3S4QCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

985008:EL144 RS02885
gene id: 985008:EL144_RS02885
uniprot id: A0A3S4QAF6
names: Similarity
messages: Belongs to the YkuD family.

985008:EL144 RS04600
gene id: 985008:EL144_RS04600
uniprot id: A0A3S4TZG6
names: Function
names: Similarity
messages: Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.

985008:EL144 RS02515
gene id: 985008:EL144_RS02515
uniprot id: A0A448F727
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters for at least IspG.

985008:EL144 RS10360
gene id: 985008:EL144_RS10360
uniprot id: A0A3S4QT77
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

985008:EL144 RS07460
gene id: 985008:EL144_RS07460
uniprot id: A0A3S4PTK3
names: Similarity
messages: Belongs to the type-I restriction system S methylase family.

985008:EL144 RS03520
gene id: 985008:EL144_RS03520
uniprot id: A0A448F7L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS02870
gene id: 985008:EL144_RS02870
uniprot id: A0A3S4TPK5
names: Function
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.
messages: E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

985008:EL144 RS11065
gene id: 985008:EL144_RS11065
uniprot id: A0A3S4PUN1
names: Similarity
messages: Belongs to the UPF0250 family.

985008:EL144 RS05595
gene id: 985008:EL144_RS05595
uniprot id: A0A448F8P1
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

985008:EL144 RS00395
gene id: 985008:EL144_RS00395
uniprot id: A0A3S4RG84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

985008:EL144 RS05345
gene id: 985008:EL144_RS05345
uniprot id: A0A448F8R2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division.
messages: Belongs to the ZapA family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer. Interacts with FtsZ.

985008:EL144 RS08670
gene id: 985008:EL144_RS08670
uniprot id: A0A448FAF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

985008:EL144 RS06770
gene id: 985008:EL144_RS06770
uniprot id: A0A448F9H3
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

985008:EL144 RS02215
gene id: 985008:EL144_RS02215
uniprot id: A0A3S4RGR0
names: Similarity
messages: Belongs to the UPF0438 family.

985008:EL144 RS03145
gene id: 985008:EL144_RS03145
uniprot id: A0A448F7J3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family. RNase II subfamily.
messages: Cytoplasm
messages: Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.

985008:EL144 RS05870
gene id: 985008:EL144_RS05870
uniprot id: A0A448F907
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS05370
gene id: 985008:EL144_RS05370
uniprot id: A0A448F917
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

985008:EL144 RS03085
gene id: 985008:EL144_RS03085
uniprot id: A0A3S4Q4C6
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

985008:EL144 RS06315
gene id: 985008:EL144_RS06315
uniprot id: A0A448F9J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

985008:EL144 RS10140
gene id: 985008:EL144_RS10140
uniprot id: A0A3S5ECX3
names: Cofactor
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.

985008:EL144 RS07940
gene id: 985008:EL144_RS07940
uniprot id: A0A3S4QSL4
names: Similarity
messages: Belongs to the peptidase C40 family.

985008:EL144 RS10480
gene id: 985008:EL144_RS10480
uniprot id: A0A448FC00
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS09120
gene id: 985008:EL144_RS09120
uniprot id: A0A3S4QC73
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

985008:EL144 RS11060
gene id: 985008:EL144_RS11060
uniprot id: A0A3S4S5I3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

985008:EL144 RS08585
gene id: 985008:EL144_RS08585
uniprot id: A0A3S5ECV6
names: Similarity
messages: Belongs to the disproportionating enzyme family.

985008:EL144 RS10150
gene id: 985008:EL144_RS10150
uniprot id: A0A448FBQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Anchors the catalytic components of the fumarate reductase complex to the cell membrane, binds quinones.
messages: Belongs to the FrdD family.
messages: Cell membrane
messages: Part of an enzyme complex containing four subunits: a flavoprotein (FrdA), an iron-sulfur protein (FrdB), and two hydrophobic anchor proteins (FrdC and FrdD).

985008:EL144 RS01380
gene id: 985008:EL144_RS01380
uniprot id: A0A3S4QA28
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS04250
gene id: 985008:EL144_RS04250
uniprot id: A0A448F7X0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. HflK subfamily.
messages: HflC and HflK could encode or regulate a protease.
messages: HflC and HflK may interact to form a multimeric complex.
messages: Membrane

985008:EL144 RS05225
gene id: 985008:EL144_RS05225
uniprot id: A0A3S5ECS2
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09855
gene id: 985008:EL144_RS09855
uniprot id: A0A3S4TRJ4
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

985008:EL144 RS04590
gene id: 985008:EL144_RS04590
uniprot id: A0A448F882
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

985008:EL144 RS03820
gene id: 985008:EL144_RS03820
uniprot id: A0A448F7T0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RlmKL family.
messages: Cytoplasm
messages: Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA.

985008:EL144 RS05360
gene id: 985008:EL144_RS05360
uniprot id: A0A448F8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

985008:EL144 RS02745
gene id: 985008:EL144_RS02745
uniprot id: A0A448F776
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuC/DcuD transporter (TC 2.A.61) family.
messages: Membrane

985008:EL144 RS04860
gene id: 985008:EL144_RS04860
uniprot id: A0A448F895
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

985008:EL144 RS04510
gene id: 985008:EL144_RS04510
uniprot id: A0A3S4S3K0
names: Function
names: Similarity
messages: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage.
messages: Belongs to the Nudix hydrolase family. RppH subfamily.

985008:EL144 RS07920
gene id: 985008:EL144_RS07920
uniprot id: A0A3S4PTQ6
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

985008:EL144 RS08040
gene id: 985008:EL144_RS08040
uniprot id: A0A3S4U0F3
names: Similarity
messages: Belongs to the HupF/HypC family.

985008:EL144 RS07810
gene id: 985008:EL144_RS07810
uniprot id: A0A3S4U0D3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

985008:EL144 RS08340
gene id: 985008:EL144_RS08340
uniprot id: A0A3S4Q613
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS06550
gene id: 985008:EL144_RS06550
uniprot id: A0A448F9S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tellurite-resistance/dicarboxylate transporter (TDT) family.
messages: Membrane

985008:EL144 RS07925
gene id: 985008:EL144_RS07925
uniprot id: A0A448FAE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the outer membrane OOP (TC 1.B.6) superfamily. OmpA family.
messages: Cell outer membrane
messages: Membrane
messages: Monomer and homodimer.
messages: The extracellular loops are most variable in sequence, and in some bacteria confer sensitivity to phage and/or colicins.
messages: With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.

985008:EL144 RS00365
gene id: 985008:EL144_RS00365
uniprot id: A0A448F6B4
names: Similarity
messages: Belongs to the skp family.

985008:EL144 RS02825
gene id: 985008:EL144_RS02825
uniprot id: A0A3S5ECP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FdhE family.
messages: Cytoplasm
messages: Necessary for formate dehydrogenase activity.

985008:EL144 RS04985
gene id: 985008:EL144_RS04985
uniprot id: A0A3S4Q4Y2
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase Slt family.
messages: Cell outer membrane
messages: In the C-terminal section; belongs to the transglycosylase Slt family.
messages: In the N-terminal section; belongs to the bacterial solute-binding protein 3 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella.
messages: The N-terminal domain does not have lytic activity and probably modulates enzymatic activity. The C-terminal domain is the catalytic active domain.

985008:EL144 RS00175
gene id: 985008:EL144_RS00175
uniprot id: A0A3S4RG66
names: Similarity
messages: Belongs to the ThrE exporter (TC 2.A.79) family.

985008:EL144 RS08515
gene id: 985008:EL144_RS08515
uniprot id: A0A3S4QC14
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (MalK), two transmembrane proteins (MalG and MalF) and a solute-binding protein (MalE).

985008:EL144 RS05075
gene id: 985008:EL144_RS05075
uniprot id: A0A3S4PYA8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

985008:EL144 RS03210
gene id: 985008:EL144_RS03210
uniprot id: A0A448F7F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SeqA family.
messages: Cytoplasm
messages: Homodimer. Polymerizes to form helical filaments.
messages: Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re-initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.

985008:EL144 RS05280
gene id: 985008:EL144_RS05280
uniprot id: A0A3S4QRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

985008:EL144 RS10350
gene id: 985008:EL144_RS10350
uniprot id: A0A448FBE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbD/TolR family.
messages: Cell inner membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

985008:EL144 RS10840
gene id: 985008:EL144_RS10840
uniprot id: A0A3S4QCM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPSP synthase family. MurA subfamily.
messages: Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.
messages: Cytoplasm

985008:EL144 RS09950
gene id: 985008:EL144_RS09950
uniprot id: A0A448FBL1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07370
gene id: 985008:EL144_RS07370
uniprot id: A0A448F9K8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

985008:EL144 RS04220
gene id: 985008:EL144_RS04220
uniprot id: A0A3S4PY18
names: Similarity
messages: Belongs to the NAPRTase family.

985008:EL144 RS08330
gene id: 985008:EL144_RS08330
uniprot id: A0A3S4U0I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS04980
gene id: 985008:EL144_RS04980
uniprot id: A0A448F8Y3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

985008:EL144 RS02070
gene id: 985008:EL144_RS02070
uniprot id: A0A3S4QQT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.
messages: Membrane
messages: Required for nicotinamide riboside transport across the inner membrane.

985008:EL144 RS05845
gene id: 985008:EL144_RS05845
uniprot id: A0A3S4TQF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

985008:EL144 RS03660
gene id: 985008:EL144_RS03660
uniprot id: A0A3S5ECQ5
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

985008:EL144 RS08635
gene id: 985008:EL144_RS08635
uniprot id: A0A3S4QC24
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

985008:EL144 RS02950
gene id: 985008:EL144_RS02950
uniprot id: A0A448F7K3
names: Similarity
messages: Belongs to the SAICAR synthetase family.

985008:EL144 RS11140
gene id: 985008:EL144_RS11140
uniprot id: A0A3S4RJ63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

985008:EL144 RS10610
gene id: 985008:EL144_RS10610
uniprot id: A0A3S4S5D1
names: Similarity
messages: Belongs to the thioredoxin family.

985008:EL144 RS03775
gene id: 985008:EL144_RS03775
uniprot id: A0A448F861
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS11145
gene id: 985008:EL144_RS11145
uniprot id: A0A3S4QCQ7
names: Function
names: Similarity
messages: Belongs to the DUF177 domain family.
messages: Plays a role in synthesis, processing and/or stability of 23S rRNA.

985008:EL144 RS03230
gene id: 985008:EL144_RS03230
uniprot id: A0A3S4QR42
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS07355
gene id: 985008:EL144_RS07355
uniprot id: A0A448F9T2
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

985008:EL144 RS04755
gene id: 985008:EL144_RS04755
uniprot id: A0A3S4TQ30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmC/CycZ/HelC family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

985008:EL144 RS09245
gene id: 985008:EL144_RS09245
uniprot id: A0A3S4U0T4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell inner membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS01320
gene id: 985008:EL144_RS01320
uniprot id: A0A3S5ECN2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemG family.
messages: Binds 1 FMN non-covalently per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX; under anaerobic conditions uses menaquinone as an electron acceptor, under aerobic conditions uses ubiquinone as an electron acceptor.
messages: Cell membrane

985008:EL144 RS05780
gene id: 985008:EL144_RS05780
uniprot id: A0A448F8U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS04610
gene id: 985008:EL144_RS04610
uniprot id: A0A448F8K3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

985008:EL144 RS05065
gene id: 985008:EL144_RS05065
uniprot id: A0A448F8U1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

985008:EL144 RS06000
gene id: 985008:EL144_RS06000
uniprot id: A0A3S5ECT0
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

985008:EL144 RS01450
gene id: 985008:EL144_RS01450
uniprot id: A0A3S4QA38
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

985008:EL144 RS06745
gene id: 985008:EL144_RS06745
uniprot id: A0A3S4S478
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10040
gene id: 985008:EL144_RS10040
uniprot id: A0A3S4RIX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

985008:EL144 RS03690
gene id: 985008:EL144_RS03690
uniprot id: A0A448F852
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. CmoB family.
messages: Catalyzes carboxymethyl transfer from carboxy-S-adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs.
messages: Homotetramer.

985008:EL144 RS09200
gene id: 985008:EL144_RS09200
uniprot id: A0A3S4QC83
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

985008:EL144 RS09970
gene id: 985008:EL144_RS09970
uniprot id: A0A448FB79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. GalK subfamily.
messages: Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS03075
gene id: 985008:EL144_RS03075
uniprot id: A0A3S5ECP9
names: Similarity
messages: Belongs to the acylphosphatase family.

985008:EL144 RS08580
gene id: 985008:EL144_RS08580
uniprot id: A0A448FA97
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

985008:EL144 RS08505
gene id: 985008:EL144_RS08505
uniprot id: A0A3S4TR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins.
messages: Periplasm

985008:EL144 RS05860
gene id: 985008:EL144_RS05860
uniprot id: A0A3S4QB82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

985008:EL144 RS03730
gene id: 985008:EL144_RS03730
uniprot id: A0A3S4TZ77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

985008:EL144 RS08355
gene id: 985008:EL144_RS08355
uniprot id: A0A3S4RIG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

985008:EL144 RS08280
gene id: 985008:EL144_RS08280
uniprot id: A0A3S4TR29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

985008:EL144 RS04815
gene id: 985008:EL144_RS04815
uniprot id: A0A3S4TZI2
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

985008:EL144 RS04940
gene id: 985008:EL144_RS04940
uniprot id: A0A448F8I3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

985008:EL144 RS01175
gene id: 985008:EL144_RS01175
uniprot id: A0A448F6Q1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

985008:EL144 RS07040
gene id: 985008:EL144_RS07040
uniprot id: A0A3S4S4B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

985008:EL144 RS05760
gene id: 985008:EL144_RS05760
uniprot id: A0A448F8S6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

985008:EL144 RS04535
gene id: 985008:EL144_RS04535
uniprot id: A0A448F843
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

985008:EL144 RS08185
gene id: 985008:EL144_RS08185
uniprot id: A0A3S4QSN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gluconeogenesis factor family.
messages: Cytoplasm
messages: Required for morphogenesis under gluconeogenic growth conditions.

985008:EL144 RS01935
gene id: 985008:EL144_RS01935
uniprot id: A0A448F756
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

985008:EL144 RS09325
gene id: 985008:EL144_RS09325
uniprot id: A0A448FB96
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09845
gene id: 985008:EL144_RS09845
uniprot id: A0A3S4Q6H3
names: Function
names: Similarity
messages: Belongs to the N(4)-acetylcytidine amidohydrolase family.
messages: Catalyzes the hydrolysis of N(4)-acetylcytidine (ac4C).

985008:EL144 RS01190
gene id: 985008:EL144_RS01190
uniprot id: A0A3S4QQI2
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS02405
gene id: 985008:EL144_RS02405
uniprot id: A0A448F713
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

985008:EL144 RS10460
gene id: 985008:EL144_RS10460
uniprot id: A0A3S4QT87
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Binds 1 nickel ion per subunit.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

985008:EL144 RS10570
gene id: 985008:EL144_RS10570
uniprot id: A0A448FBC5
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS08250
gene id: 985008:EL144_RS08250
uniprot id: A0A448FAK6
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

985008:EL144 RS05275
gene id: 985008:EL144_RS05275
uniprot id: A0A448F909
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

985008:EL144 RS07725
gene id: 985008:EL144_RS07725
uniprot id: A0A3S4PTM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

985008:EL144 RS10025
gene id: 985008:EL144_RS10025
uniprot id: A0A3S4PZV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05605
gene id: 985008:EL144_RS05605
uniprot id: A0A3S4RHQ3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

985008:EL144 RS10295
gene id: 985008:EL144_RS10295
uniprot id: A0A3S4PZW9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS04990
gene id: 985008:EL144_RS04990
uniprot id: A0A448F8J7
names: Function
names: Similarity
messages: Belongs to the DHNA family.
messages: Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.

985008:EL144 RS00645
gene id: 985008:EL144_RS00645
uniprot id: A0A448F624
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ApbE family.
messages: Cell inner membrane
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

985008:EL144 RS09225
gene id: 985008:EL144_RS09225
uniprot id: A0A3S4PU47
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

985008:EL144 RS06810
gene id: 985008:EL144_RS06810
uniprot id: A0A3S5ECT8
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

985008:EL144 RS06710
gene id: 985008:EL144_RS06710
uniprot id: A0A3S4U013
names: Similarity
messages: Belongs to the FBPase class 2 family.

985008:EL144 RS02865
gene id: 985008:EL144_RS02865
uniprot id: A0A448F7A2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

985008:EL144 RS05365
gene id: 985008:EL144_RS05365
uniprot id: A0A3S4S3U6
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

985008:EL144 RS02695
gene id: 985008:EL144_RS02695
uniprot id: A0A3S4S2X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: The complex is composed of two ATP-binding proteins (ThiQ), two transmembrane proteins (ThiP) and a solute-binding protein (ThiB).

985008:EL144 RS11035
gene id: 985008:EL144_RS11035
uniprot id: A0A3S4Q051
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS03360
gene id: 985008:EL144_RS03360
uniprot id: A0A3S4PS98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

985008:EL144 RS08345
gene id: 985008:EL144_RS08345
uniprot id: A0A3S4PZB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

985008:EL144 RS01490
gene id: 985008:EL144_RS01490
uniprot id: A0A3S5ECN4
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

985008:EL144 RS02790
gene id: 985008:EL144_RS02790
uniprot id: A0A448F7Q1
names: Function
names: Similarity
messages: Belongs to the HypA/HybF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.

985008:EL144 RS03545
gene id: 985008:EL144_RS03545
uniprot id: A0A3S5ECQ4
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS00635
gene id: 985008:EL144_RS00635
uniprot id: A0A448F683
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm

985008:EL144 RS08350
gene id: 985008:EL144_RS08350
uniprot id: A0A3S4TR36
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

985008:EL144 RS08620
gene id: 985008:EL144_RS08620
uniprot id: A0A448FAE3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Homohexamer.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the CobB/CobQ family.
messages: Involved in acetate metabolism.
messages: The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.

985008:EL144 RS05905
gene id: 985008:EL144_RS05905
uniprot id: A0A448F9F6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS02495
gene id: 985008:EL144_RS02495
uniprot id: A0A448F725
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. WecA subfamily.
messages: Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55).
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS04475
gene id: 985008:EL144_RS04475
uniprot id: A0A3S4Q4T2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS09035
gene id: 985008:EL144_RS09035
uniprot id: A0A3S4S4W5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07695
gene id: 985008:EL144_RS07695
uniprot id: A0A3S4QBS1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

985008:EL144 RS03930
gene id: 985008:EL144_RS03930
uniprot id: A0A3S5ECQ8
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurE subfamily.
messages: Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.
messages: Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS03525
gene id: 985008:EL144_RS03525
uniprot id: A0A448F7L9
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

985008:EL144 RS00345
gene id: 985008:EL144_RS00345
uniprot id: A0A448F5V6
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

985008:EL144 RS07105
gene id: 985008:EL144_RS07105
uniprot id: A0A3S5ECU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

985008:EL144 RS08415
gene id: 985008:EL144_RS08415
uniprot id: A0A448FAA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS11595
gene id: 985008:EL144_RS11595
uniprot id: A0A3S4S4N6
names: Similarity
messages: Belongs to the UPF0181 family.

985008:EL144 RS10340
gene id: 985008:EL144_RS10340
uniprot id: A0A448FB94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

985008:EL144 RS10730
gene id: 985008:EL144_RS10730
uniprot id: A0A3S4Q6Q6
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

985008:EL144 RS05025
gene id: 985008:EL144_RS05025
uniprot id: A0A448F8Z3
names: Similarity
messages: Belongs to the UPF0145 family.

985008:EL144 RS05735
gene id: 985008:EL144_RS05735
uniprot id: A0A3S4S3Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell inner membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

985008:EL144 RS07660
gene id: 985008:EL144_RS07660
uniprot id: A0A448F9S7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

985008:EL144 RS04150
gene id: 985008:EL144_RS04150
uniprot id: A0A3S4QAS1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RraA family.
messages: Cytoplasm
messages: Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome.
messages: Homotrimer. Binds to both RNA-binding sites in the C-terminal region of Rne and to RhlB.

985008:EL144 RS03430
gene id: 985008:EL144_RS03430
uniprot id: A0A448F7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS04360
gene id: 985008:EL144_RS04360
uniprot id: A0A3S4QRG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

985008:EL144 RS09180
gene id: 985008:EL144_RS09180
uniprot id: A0A3S4TRC5
names: Similarity
messages: Belongs to the peptidase S1C family.

985008:EL144 RS05815
gene id: 985008:EL144_RS05815
uniprot id: A0A448F8T6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

985008:EL144 RS02995
gene id: 985008:EL144_RS02995
uniprot id: A0A448F7G9
names: Similarity
messages: Belongs to the ROK (NagC/XylR) family.

985008:EL144 RS04305
gene id: 985008:EL144_RS04305
uniprot id: A0A3S4Q4R1
names: Similarity
names: Subunit
messages: Belongs to the beta-eliminating lyase family.
messages: Homotetramer.

985008:EL144 RS06430
gene id: 985008:EL144_RS06430
uniprot id: A0A3S4PYR2
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

985008:EL144 RS01480
gene id: 985008:EL144_RS01480
uniprot id: A0A3S4TYM4
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS09830
gene id: 985008:EL144_RS09830
uniprot id: A0A448FB01
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

985008:EL144 RS06160
gene id: 985008:EL144_RS06160
uniprot id: A0A3S4TQI7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

985008:EL144 RS08870
gene id: 985008:EL144_RS08870
uniprot id: A0A448FAK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

985008:EL144 RS02295
gene id: 985008:EL144_RS02295
uniprot id: A0A448F6Z4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

985008:EL144 RS10870
gene id: 985008:EL144_RS10870
uniprot id: A0A3S5ECY0
names: Similarity
messages: Belongs to the CdaR family.

985008:EL144 RS06595
gene id: 985008:EL144_RS06595
uniprot id: A0A3S4RHZ3
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NapC/NirT/NrfH family.
messages: Binds 4 heme groups per subunit.
messages: Membrane

985008:EL144 RS02200
gene id: 985008:EL144_RS02200
uniprot id: A0A448F6V9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MobA family.
messages: Cytoplasm
messages: Monomer.
messages: The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.
messages: Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.

985008:EL144 RS03490
gene id: 985008:EL144_RS03490
uniprot id: A0A448F806
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

985008:EL144 RS09705
gene id: 985008:EL144_RS09705
uniprot id: A0A3S4S535
names: Similarity
messages: Belongs to the HesB/IscA family.

985008:EL144 RS09255
gene id: 985008:EL144_RS09255
uniprot id: A0A3S4Q6B9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell inner membrane
messages: Membrane
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS10835
gene id: 985008:EL144_RS10835
uniprot id: A0A3S4RJ33
names: Similarity
messages: Belongs to the BolA/IbaG family.

985008:EL144 RS03760
gene id: 985008:EL144_RS03760
uniprot id: A0A3S4TPT6
names: Function
messages: Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase.

985008:EL144 RS05290
gene id: 985008:EL144_RS05290
uniprot id: A0A3S5ECS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

985008:EL144 RS04125
gene id: 985008:EL144_RS04125
uniprot id: A0A448F8D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

985008:EL144 RS10470
gene id: 985008:EL144_RS10470
uniprot id: A0A3S5ECX6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS06900
gene id: 985008:EL144_RS06900
uniprot id: A0A448F9X0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

985008:EL144 RS02060
gene id: 985008:EL144_RS02060
uniprot id: A0A448F6Z5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DEAD box helicase family. SrmB subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity.
messages: Interacts with the 50S ribosomal subunit.

985008:EL144 RS10845
gene id: 985008:EL144_RS10845
uniprot id: A0A3S4S5F5
names: Similarity
messages: Belongs to the UPF0307 family.

985008:EL144 RS09215
gene id: 985008:EL144_RS09215
uniprot id: A0A448FAP2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.
messages: Homodimer.

985008:EL144 RS05960
gene id: 985008:EL144_RS05960
uniprot id: A0A448F906
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

985008:EL144 RS07540
gene id: 985008:EL144_RS07540
uniprot id: A0A448FAB0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LpoA family.
messages: Interacts with PBP1a.
messages: Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a).

985008:EL144 RS11015
gene id: 985008:EL144_RS11015
uniprot id: A0A3S4QTD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

985008:EL144 RS01560
gene id: 985008:EL144_RS01560
uniprot id: A0A448F6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YejK family.
messages: nucleoid

985008:EL144 RS01850
gene id: 985008:EL144_RS01850
uniprot id: A0A3S4S2P9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS10940
gene id: 985008:EL144_RS10940
uniprot id: A0A448FBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS04730
gene id: 985008:EL144_RS04730
uniprot id: A0A448F8A9
names: Function
names: Similarity
messages: Belongs to the CcmH/CycL/Ccl2/NrfF family.
messages: Possible subunit of a heme lyase.

985008:EL144 RS05505
gene id: 985008:EL144_RS05505
uniprot id: A0A3S4PYG5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

985008:EL144 RS05950
gene id: 985008:EL144_RS05950
uniprot id: A0A3S4QB92
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

985008:EL144 RS01470
gene id: 985008:EL144_RS01470
uniprot id: A0A3S4PRT2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

985008:EL144 RS11095
gene id: 985008:EL144_RS11095
uniprot id: A0A448FBR3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

985008:EL144 RS09110
gene id: 985008:EL144_RS09110
uniprot id: A0A3S4TRB5
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

985008:EL144 RS04300
gene id: 985008:EL144_RS04300
uniprot id: A0A3S5ECR2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation.
messages: May be beta-lysylated on the epsilon-amino group of Lys-34 by the combined action of EpmA and EpmB, and then hydroxylated on the C5 position of the same residue by EpmC (if this protein is present). Lysylation is critical for the stimulatory effect of EF-P on peptide-bond formation. The lysylation moiety may extend toward the peptidyltransferase center and stabilize the terminal 3-CCA end of the tRNA. Hydroxylation of the C5 position on Lys-34 may allow additional potential stabilizing hydrogen-bond interactions with the P-tRNA.

985008:EL144 RS04130
gene id: 985008:EL144_RS04130
uniprot id: A0A3S4Q4P2
names: Function
names: Subcellular Location Annotation
messages: Chaperone that serves for the intracellular sequestration and transport of Cu(+). Delivers Cu(+) to the copper-exporting P-type ATPase A (CopA).
messages: Cytoplasm

985008:EL144 RS00615
gene id: 985008:EL144_RS00615
uniprot id: A0A3S4S2B9
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS03415
gene id: 985008:EL144_RS03415
uniprot id: A0A3S4QAK1
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

985008:EL144 RS10290
gene id: 985008:EL144_RS10290
uniprot id: A0A3S4Q6L2
names: Function
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.

985008:EL144 RS03340
gene id: 985008:EL144_RS03340
uniprot id: A0A448F7G3
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05810
gene id: 985008:EL144_RS05810
uniprot id: A0A448F8X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

985008:EL144 RS05060
gene id: 985008:EL144_RS05060
uniprot id: A0A448F8W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurJ/MviN family.
messages: Cell inner membrane
messages: Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
messages: Membrane

985008:EL144 RS09985
gene id: 985008:EL144_RS09985
uniprot id: A0A3S4PUC5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial solute-binding protein 2 family.
messages: Periplasm
messages: The ABC transporter complex is composed of one ATP-binding protein (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).

985008:EL144 RS07330
gene id: 985008:EL144_RS07330
uniprot id: A0A3S4QBP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS07625
gene id: 985008:EL144_RS07625
uniprot id: A0A448F9W2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

985008:EL144 RS00385
gene id: 985008:EL144_RS00385
uniprot id: A0A3S4PWW4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide.
messages: Homodimer.

985008:EL144 RS09620
gene id: 985008:EL144_RS09620
uniprot id: A0A3S4RIT9
names: Function
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.

985008:EL144 RS10545
gene id: 985008:EL144_RS10545
uniprot id: A0A3S5ECX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS09945
gene id: 985008:EL144_RS09945
uniprot id: A0A3S4RIX0
names: Similarity
messages: Belongs to the UPF0265 family.

985008:EL144 RS06890
gene id: 985008:EL144_RS06890
uniprot id: A0A448F9V6
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

985008:EL144 RS05030
gene id: 985008:EL144_RS05030
uniprot id: A0A448F8H4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

985008:EL144 RS08710
gene id: 985008:EL144_RS08710
uniprot id: A0A3S4RIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS08655
gene id: 985008:EL144_RS08655
uniprot id: A0A3S4PTY0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10195
gene id: 985008:EL144_RS10195
uniprot id: A0A448FB58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS09220
gene id: 985008:EL144_RS09220
uniprot id: A0A448FB76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ArgR family.
messages: Cytoplasm
messages: Regulates arginine biosynthesis genes.

985008:EL144 RS06680
gene id: 985008:EL144_RS06680
uniprot id: A0A3S4S471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

985008:EL144 RS04405
gene id: 985008:EL144_RS04405
uniprot id: A0A448F888
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

985008:EL144 RS05335
gene id: 985008:EL144_RS05335
uniprot id: A0A3S4RHM2
names: Similarity
messages: Belongs to the peptidase M24B family.

985008:EL144 RS08885
gene id: 985008:EL144_RS08885
uniprot id: A0A3S4S4V0
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

985008:EL144 RS04020
gene id: 985008:EL144_RS04020
uniprot id: A0A448F7V8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endoribonuclease YbeY family.
messages: Binds 1 zinc ion.
messages: Cytoplasm
messages: Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.

985008:EL144 RS06415
gene id: 985008:EL144_RS06415
uniprot id: A0A3S4TZZ0
names: Similarity
messages: Belongs to the DsrF/TusC family.

985008:EL144 RS10850
gene id: 985008:EL144_RS10850
uniprot id: A0A3S4PUK0
names: Similarity
messages: Belongs to the peptidase U62 family.

985008:EL144 RS00890
gene id: 985008:EL144_RS00890
uniprot id: A0A3S5ECM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Homodimer. Forms a membrane-associated complex with FtsX.
messages: Part of the ABC transporter FtsEX involved in cellular division. Important for assembly or stability of the septal ring.

985008:EL144 RS05710
gene id: 985008:EL144_RS05710
uniprot id: A0A3S4TQE2
names: Function
names: Similarity
messages: Belongs to the Ap4A hydrolase family.
messages: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP.

985008:EL144 RS05310
gene id: 985008:EL144_RS05310
uniprot id: A0A3S4Q526
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

985008:EL144 RS09440
gene id: 985008:EL144_RS09440
uniprot id: A0A448FB91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS02580
gene id: 985008:EL144_RS02580
uniprot id: A0A3S4TPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0382 family.
messages: Membrane

985008:EL144 RS05535
gene id: 985008:EL144_RS05535
uniprot id: A0A448F992
names: Similarity
messages: Belongs to the UPF0270 family.

985008:EL144 RS09390
gene id: 985008:EL144_RS09390
uniprot id: A0A448FB78
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family.
messages: Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A).
messages: Cell inner membrane

985008:EL144 RS05895
gene id: 985008:EL144_RS05895
uniprot id: A0A448F9A0
names: Similarity
messages: Belongs to the carbamate kinase family.

985008:EL144 RS00925
gene id: 985008:EL144_RS00925
uniprot id: A0A3S4RGE1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS09960
gene id: 985008:EL144_RS09960
uniprot id: A0A448FBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS02895
gene id: 985008:EL144_RS02895
uniprot id: A0A448F7M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ProQ family.
messages: Cytoplasm
messages: RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities.

985008:EL144 RS08525
gene id: 985008:EL144_RS08525
uniprot id: A0A448FA83
names: Cofactor
messages: Binds 1 Ca(2+) ion per subunit.

985008:EL144 RS09485
gene id: 985008:EL144_RS09485
uniprot id: A0A3S5ECW6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS02330
gene id: 985008:EL144_RS02330
uniprot id: A0A448F7A0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

985008:EL144 RS10355
gene id: 985008:EL144_RS10355
uniprot id: A0A3S4PUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

985008:EL144 RS03260
gene id: 985008:EL144_RS03260
uniprot id: A0A448F7V1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

985008:EL144 RS02760
gene id: 985008:EL144_RS02760
uniprot id: A0A3S4TPJ4
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.

985008:EL144 RS11085
gene id: 985008:EL144_RS11085
uniprot id: A0A448FBR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

985008:EL144 RS02775
gene id: 985008:EL144_RS02775
uniprot id: A0A448F7K1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

985008:EL144 RS10640
gene id: 985008:EL144_RS10640
uniprot id: A0A448FBJ7
names: Similarity
messages: Belongs to the aspartokinase family.

985008:EL144 RS03875
gene id: 985008:EL144_RS03875
uniprot id: A0A448F885
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

985008:EL144 RS01355
gene id: 985008:EL144_RS01355
uniprot id: A0A448F6E6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Membrane

985008:EL144 RS03320
gene id: 985008:EL144_RS03320
uniprot id: A0A3S4RH04
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

985008:EL144 RS09880
gene id: 985008:EL144_RS09880
uniprot id: A0A3S4PUB5
names: Similarity
names: Subunit
messages: Belongs to the ArsC family.
messages: Monomer.

985008:EL144 RS07535
gene id: 985008:EL144_RS07535
uniprot id: A0A448FAB2
names: Similarity
messages: Belongs to the UPF0102 family.

985008:EL144 RS03670
gene id: 985008:EL144_RS03670
uniprot id: A0A448F7P5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 2 residues (Tyr-54 and Arg-57) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.
messages: Belongs to the sirtuin family. Class III subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.

985008:EL144 RS08745
gene id: 985008:EL144_RS08745
uniprot id: A0A448FB07
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.

985008:EL144 RS03855
gene id: 985008:EL144_RS03855
uniprot id: A0A3S4TPU7
names: Similarity
messages: Belongs to the ArsC family.

985008:EL144 RS06185
gene id: 985008:EL144_RS06185
uniprot id: A0A448F901
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

985008:EL144 RS02520
gene id: 985008:EL144_RS02520
uniprot id: A0A448F721
names: Similarity
messages: Belongs to the UPF0231 family.

985008:EL144 RS07715
gene id: 985008:EL144_RS07715
uniprot id: A0A448F9Y4
names: Similarity
messages: Belongs to the UPF0260 family.

985008:EL144 RS03955
gene id: 985008:EL144_RS03955
uniprot id: A0A3S4PXZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

985008:EL144 RS08450
gene id: 985008:EL144_RS08450
uniprot id: A0A448FAG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

985008:EL144 RS05520
gene id: 985008:EL144_RS05520
uniprot id: A0A3S4QB54
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.

985008:EL144 RS06630
gene id: 985008:EL144_RS06630
uniprot id: A0A3S4U005
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

985008:EL144 RS00915
gene id: 985008:EL144_RS00915
uniprot id: A0A3S4TP18
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS06065
gene id: 985008:EL144_RS06065
uniprot id: A0A3S4RHU5
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

985008:EL144 RS00375
gene id: 985008:EL144_RS00375
uniprot id: A0A448F5Y1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

985008:EL144 RS04440
gene id: 985008:EL144_RS04440
uniprot id: A0A448F8N7
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

985008:EL144 RS01530
gene id: 985008:EL144_RS01530
uniprot id: A0A3S4RGK0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

985008:EL144 RS07490
gene id: 985008:EL144_RS07490
uniprot id: A0A448FAA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.
messages: Cytoplasm
messages: Functions in trans to edit the amino acid from incorrectly charged Cys-tRNA(Pro) via a Cys-tRNA(Pro) deacylase activity.

985008:EL144 RS06270
gene id: 985008:EL144_RS06270
uniprot id: A0A3S4QBC2
names: Similarity
messages: Belongs to the HSP15 family.

985008:EL144 RS07755
gene id: 985008:EL144_RS07755
uniprot id: A0A448F9U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS10490
gene id: 985008:EL144_RS10490
uniprot id: A0A3S4TRQ0
names: Function
names: Similarity
messages: Belongs to the QueH family.
messages: Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).

985008:EL144 RS04345
gene id: 985008:EL144_RS04345
uniprot id: A0A448F840
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activation of pyruvate formate-lyase 1 under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
messages: Belongs to the organic radical-activating enzymes family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm

985008:EL144 RS07160
gene id: 985008:EL144_RS07160
uniprot id: A0A3S4QBL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS01045
gene id: 985008:EL144_RS01045
uniprot id: A0A3S4Q3T6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

985008:EL144 RS06420
gene id: 985008:EL144_RS06420
uniprot id: A0A3S5ECT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsrE/TusD family.
messages: Cytoplasm

985008:EL144 RS05405
gene id: 985008:EL144_RS05405
uniprot id: A0A448F8N2
names: Similarity
messages: Belongs to the YggT family.

985008:EL144 RS00520
gene id: 985008:EL144_RS00520
uniprot id: A0A3S4PWY5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

985008:EL144 RS04500
gene id: 985008:EL144_RS04500
uniprot id: A0A448F824
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

985008:EL144 RS09745
gene id: 985008:EL144_RS09745
uniprot id: A0A3S4PZR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Efflux system for nickel and cobalt.
messages: Membrane

985008:EL144 RS06610
gene id: 985008:EL144_RS06610
uniprot id: A0A448F983
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

985008:EL144 RS07135
gene id: 985008:EL144_RS07135
uniprot id: A0A448FA13
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

985008:EL144 RS00470
gene id: 985008:EL144_RS00470
uniprot id: A0A448F6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

985008:EL144 RS05790
gene id: 985008:EL144_RS05790
uniprot id: A0A3S5ECS8
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

985008:EL144 RS00940
gene id: 985008:EL144_RS00940
uniprot id: A0A3S4PRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS08825
gene id: 985008:EL144_RS08825
uniprot id: A0A3S4U0N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

985008:EL144 RS03255
gene id: 985008:EL144_RS03255
uniprot id: A0A448F7G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the OMP decarboxylase family. Type 1 subfamily.
messages: Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
messages: Homodimer.

985008:EL144 RS03950
gene id: 985008:EL144_RS03950
uniprot id: A0A448F7R6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MraZ family.
messages: Belongs to the VapB family.
messages: Forms oligomers.
messages: nucleoid

985008:EL144 RS01170
gene id: 985008:EL144_RS01170
uniprot id: A0A3S4S2I9
names: Similarity
messages: Belongs to the RNase T2 family.

985008:EL144 RS05855
gene id: 985008:EL144_RS05855
uniprot id: A0A3S4RHS7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

985008:EL144 RS03890
gene id: 985008:EL144_RS03890
uniprot id: A0A3S4QAP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

985008:EL144 RS02585
gene id: 985008:EL144_RS02585
uniprot id: A0A448F7H7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0756 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS06235
gene id: 985008:EL144_RS06235
uniprot id: A0A3S4Q5C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol monophosphatase superfamily. CysQ family.
messages: Cell inner membrane
messages: Converts adenosine-3',5'-bisphosphate (PAP) to AMP.

985008:EL144 RS06500
gene id: 985008:EL144_RS06500
uniprot id: A0A3S4PT87
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

985008:EL144 RS08395
gene id: 985008:EL144_RS08395
uniprot id: A0A3S4PZC7
names: Caution
names: Domain
names: Function
names: Subunit
messages: Consists of two structural and functional domains: an N-terminal DNA-binding domain, approximately the first 60 residues, and a larger C-terminal domain, approximately 280 residues, which imparts the function of corepressor binding and oligomerization.
messages: Homodimer.
messages: Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS03180
gene id: 985008:EL144_RS03180
uniprot id: A0A3S4TPN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LpxL/LpxM/LpxP family. LpxM subfamily.
messages: Catalyzes the transfer of myristate from myristoyl-acyl carrier protein (ACP) to Kdo(2)-(lauroyl)-lipid IV(A) to form Kdo(2)-lipid A.
messages: Cell inner membrane

985008:EL144 RS01210
gene id: 985008:EL144_RS01210
uniprot id: A0A3S4PX67
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

985008:EL144 RS07610
gene id: 985008:EL144_RS07610
uniprot id: A0A3S4PTL5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

985008:EL144 RS03980
gene id: 985008:EL144_RS03980
uniprot id: A0A448F8A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 3 family.
messages: Periplasm

985008:EL144 RS05795
gene id: 985008:EL144_RS05795
uniprot id: A0A448F980
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

985008:EL144 RS04420
gene id: 985008:EL144_RS04420
uniprot id: A0A3S4RHB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

985008:EL144 RS08900
gene id: 985008:EL144_RS08900
uniprot id: A0A3S4QSV5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS02525
gene id: 985008:EL144_RS02525
uniprot id: A0A3S4TYW8
names: Function
names: Similarity
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

985008:EL144 RS04640
gene id: 985008:EL144_RS04640
uniprot id: A0A448F8C8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecF family.
messages: Cytoplasm
messages: The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.

985008:EL144 RS03795
gene id: 985008:EL144_RS03795
uniprot id: A0A3S4QAN6
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

985008:EL144 RS08610
gene id: 985008:EL144_RS08610
uniprot id: A0A3S4TR62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0208 family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS00380
gene id: 985008:EL144_RS00380
uniprot id: A0A448F5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

985008:EL144 RS07240
gene id: 985008:EL144_RS07240
uniprot id: A0A3S4S4C8
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS08730
gene id: 985008:EL144_RS08730
uniprot id: A0A448FAY9
names: Function
names: Similarity
messages: Belongs to the AlaDH/PNT family.
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

985008:EL144 RS05995
gene id: 985008:EL144_RS05995
uniprot id: A0A448F9C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Cytoplasm
messages: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.

985008:EL144 RS03945
gene id: 985008:EL144_RS03945
uniprot id: A0A448F7W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

985008:EL144 RS10915
gene id: 985008:EL144_RS10915
uniprot id: A0A3S4S5G6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Component of the RNA degradosome, which is a multiprotein complex involved in RNA processing and mRNA degradation.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

985008:EL144 RS05915
gene id: 985008:EL144_RS05915
uniprot id: A0A3S4Q595
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. AsnA subfamily.
messages: Cytoplasm

985008:EL144 RS00680
gene id: 985008:EL144_RS00680
uniprot id: A0A3S4Q9V8
names: Similarity
messages: Belongs to the BolA/IbaG family.

985008:EL144 RS11125
gene id: 985008:EL144_RS11125
uniprot id: A0A448FCD3
names: Similarity
messages: Belongs to the fabD family.

985008:EL144 RS10950
gene id: 985008:EL144_RS10950
uniprot id: A0A448FBJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

985008:EL144 RS10255
gene id: 985008:EL144_RS10255
uniprot id: A0A448FBQ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS06290
gene id: 985008:EL144_RS06290
uniprot id: A0A3S4PT64
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS00650
gene id: 985008:EL144_RS00650
uniprot id: A0A3S4Q3N8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

985008:EL144 RS07880
gene id: 985008:EL144_RS07880
uniprot id: A0A448FAE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS09710
gene id: 985008:EL144_RS09710
uniprot id: A0A3S4PU90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

985008:EL144 RS06230
gene id: 985008:EL144_RS06230
uniprot id: A0A448F963
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS09560
gene id: 985008:EL144_RS09560
uniprot id: A0A3S5ECW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CbiQ family.
messages: Membrane

985008:EL144 RS05865
gene id: 985008:EL144_RS05865
uniprot id: A0A3S4S3Z8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

985008:EL144 RS04380
gene id: 985008:EL144_RS04380
uniprot id: A0A448F8F4
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmC subfamily.
messages: Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA.

985008:EL144 RS06655
gene id: 985008:EL144_RS06655
uniprot id: A0A3S4Q5H4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

985008:EL144 RS03445
gene id: 985008:EL144_RS03445
uniprot id: A0A3S4PSA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Membrane

985008:EL144 RS04650
gene id: 985008:EL144_RS04650
uniprot id: A0A3S4PY58
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
messages: Periplasm

985008:EL144 RS01020
gene id: 985008:EL144_RS01020
uniprot id: A0A3S4QQG3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS00210
gene id: 985008:EL144_RS00210
uniprot id: A0A448F5U8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

985008:EL144 RS02910
gene id: 985008:EL144_RS02910
uniprot id: A0A448F7S4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

985008:EL144 RS04780
gene id: 985008:EL144_RS04780
uniprot id: A0A448F8B9
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

985008:EL144 RS06545
gene id: 985008:EL144_RS06545
uniprot id: A0A448F9P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

985008:EL144 RS05695
gene id: 985008:EL144_RS05695
uniprot id: A0A448F982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

985008:EL144 RS05110
gene id: 985008:EL144_RS05110
uniprot id: A0A448F8X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CysZ family.
messages: Cell inner membrane
messages: High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway.

985008:EL144 RS06560
gene id: 985008:EL144_RS06560
uniprot id: A0A3S5ECT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

985008:EL144 RS02930
gene id: 985008:EL144_RS02930
uniprot id: A0A448F7B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein PotD/PotF family.
messages: Periplasm
messages: Required for the activity of the bacterial periplasmic transport system of putrescine.

985008:EL144 RS02755
gene id: 985008:EL144_RS02755
uniprot id: A0A3S4PXL8
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

985008:EL144 RS01325
gene id: 985008:EL144_RS01325
uniprot id: A0A3S4Q3W0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Cell inner membrane
messages: Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA.
messages: Membrane

985008:EL144 RS01000
gene id: 985008:EL144_RS01000
uniprot id: A0A3S4RGE7
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Aspartase subfamily.

985008:EL144 RS04265
gene id: 985008:EL144_RS04265
uniprot id: A0A3S4S3D8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

985008:EL144 RS02645
gene id: 985008:EL144_RS02645
uniprot id: A0A3S4TYX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family. NanA subfamily.
messages: Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
messages: Cytoplasm
messages: Homotetramer.

985008:EL144 RS11150
gene id: 985008:EL144_RS11150
uniprot id: A0A3S4S5J4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS04925
gene id: 985008:EL144_RS04925
uniprot id: A0A448F8X0
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

985008:EL144 RS08630
gene id: 985008:EL144_RS08630
uniprot id: A0A448FAB7
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS03905
gene id: 985008:EL144_RS03905
uniprot id: A0A3S4PSF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family. MurG subfamily.
messages: Cell membrane
messages: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).

985008:EL144 RS04760
gene id: 985008:EL144_RS04760
uniprot id: A0A448F8Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmB/CycW/HelB family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

985008:EL144 RS01370
gene id: 985008:EL144_RS01370
uniprot id: A0A3S4RGI3
names: Function
messages: Acts as a multifunctional adhesin involved in direct interactions with host epithelial cells and host proteins.

985008:EL144 RS10435
gene id: 985008:EL144_RS10435
uniprot id: A0A448FBG7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cx-SAM synthase family.
messages: Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
messages: Homodimer.

985008:EL144 RS00215
gene id: 985008:EL144_RS00215
uniprot id: A0A448F5U4
names: Function
names: Similarity
messages: Belongs to the transglycosylase MltG family.
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

985008:EL144 RS04775
gene id: 985008:EL144_RS04775
uniprot id: A0A3S4QAX2
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

985008:EL144 RS02635
gene id: 985008:EL144_RS02635
uniprot id: A0A3S4PS27
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. NagA family.
messages: Binds 1 divalent metal cation per subunit.

985008:EL144 RS04140
gene id: 985008:EL144_RS04140
uniprot id: A0A3S4TPX2
names: Similarity
messages: Belongs to the tRNA methyltransferase O family.

985008:EL144 RS06525
gene id: 985008:EL144_RS06525
uniprot id: A0A448F9A2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptD family.
messages: Cell outer membrane
messages: Component of the lipopolysaccharide transport and assembly complex. Interacts with LptE and LptA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.

985008:EL144 RS11720
gene id: 985008:EL144_RS11720
uniprot id: A0A448FBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family.
messages: Cell surface

985008:EL144 RS00655
gene id: 985008:EL144_RS00655
uniprot id: A0A448F6E2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

985008:EL144 RS07545
gene id: 985008:EL144_RS07545
uniprot id: A0A3S5ECU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

985008:EL144 RS00780
gene id: 985008:EL144_RS00780
uniprot id: A0A448F655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS09920
gene id: 985008:EL144_RS09920
uniprot id: A0A3S4PZU0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS02675
gene id: 985008:EL144_RS02675
uniprot id: A0A3S4TPI4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NanM family.
messages: Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Periplasm

985008:EL144 RS01920
gene id: 985008:EL144_RS01920
uniprot id: A0A3S4TPB6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

985008:EL144 RS00595
gene id: 985008:EL144_RS00595
uniprot id: A0A448F613
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

985008:EL144 RS02685
gene id: 985008:EL144_RS02685
uniprot id: A0A3S4QAD6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

985008:EL144 RS10455
gene id: 985008:EL144_RS10455
uniprot id: A0A448FBE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS02220
gene id: 985008:EL144_RS02220
uniprot id: A0A3S4QAA1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. TrmA subfamily.
messages: Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA).

985008:EL144 RS08925
gene id: 985008:EL144_RS08925
uniprot id: A0A448FAL6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

985008:EL144 RS00750
gene id: 985008:EL144_RS00750
uniprot id: A0A448F633
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. KdkA/RfaP family.
messages: Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS09380
gene id: 985008:EL144_RS09380
uniprot id: A0A3S5ECW5
names: Similarity
messages: Belongs to the SufE family.

985008:EL144 RS03050
gene id: 985008:EL144_RS03050
uniprot id: A0A448F7E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dsrC/tusE family.
messages: Cytoplasm
messages: Part of a sulfur-relay system.

985008:EL144 RS09900
gene id: 985008:EL144_RS09900
uniprot id: A0A3S4U117
names: Similarity
messages: Belongs to the aldolase class II family. AraD/FucA subfamily.

985008:EL144 RS05400
gene id: 985008:EL144_RS05400
uniprot id: A0A3S4TZQ1
names: Similarity
messages: Belongs to the UPF0235 family.

985008:EL144 RS09965
gene id: 985008:EL144_RS09965
uniprot id: A0A448FBQ2
names: Similarity
messages: Belongs to the aldose epimerase family.

985008:EL144 RS03420
gene id: 985008:EL144_RS03420
uniprot id: A0A448F7J4
names: Function
names: Similarity
messages: Belongs to the GlnE family.
messages: Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell.

985008:EL144 RS02780
gene id: 985008:EL144_RS02780
uniprot id: A0A3S4RGV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Membrane

985008:EL144 RS10520
gene id: 985008:EL144_RS10520
uniprot id: A0A3S4QCJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

985008:EL144 RS02680
gene id: 985008:EL144_RS02680
uniprot id: A0A3S4RGU6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09320
gene id: 985008:EL144_RS09320
uniprot id: A0A3S4PU57
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS06660
gene id: 985008:EL144_RS06660
uniprot id: A0A3S4PYT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

985008:EL144 RS10605
gene id: 985008:EL144_RS10605
uniprot id: A0A448FBJ8
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

985008:EL144 RS01565
gene id: 985008:EL144_RS01565
uniprot id: A0A448F6X1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamE family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

985008:EL144 RS06490
gene id: 985008:EL144_RS06490
uniprot id: A0A3S4QBE6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

985008:EL144 RS01915
gene id: 985008:EL144_RS01915
uniprot id: A0A3S4PXD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

985008:EL144 RS01535
gene id: 985008:EL144_RS01535
uniprot id: A0A448F712
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm
messages: Required for resistance to DNA-damaging agents.

985008:EL144 RS08690
gene id: 985008:EL144_RS08690
uniprot id: A0A3S4PZF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Oligosaccharide:H(+) symporter (OHS) (TC 2.A.1.5) family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS00720
gene id: 985008:EL144_RS00720
uniprot id: A0A448F6C9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS04750
gene id: 985008:EL144_RS04750
uniprot id: A0A3S4PY69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CcmD/CycX/HelD family.
messages: Cell inner membrane
messages: Membrane
messages: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes.

985008:EL144 RS05325
gene id: 985008:EL144_RS05325
uniprot id: A0A3S4TQ99
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

985008:EL144 RS01485
gene id: 985008:EL144_RS01485
uniprot id: A0A448F6H2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the thiamine-phosphate synthase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).

985008:EL144 RS08085
gene id: 985008:EL144_RS08085
uniprot id: A0A448FAH9
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.

985008:EL144 RS05770
gene id: 985008:EL144_RS05770
uniprot id: A0A448F8Y6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

985008:EL144 RS01940
gene id: 985008:EL144_RS01940
uniprot id: A0A448F791
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

985008:EL144 RS04175
gene id: 985008:EL144_RS04175
uniprot id: A0A448F8E3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MutH family.
messages: Cytoplasm
messages: Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair.

985008:EL144 RS10430
gene id: 985008:EL144_RS10430
uniprot id: A0A3S4S5B0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05140
gene id: 985008:EL144_RS05140
uniprot id: A0A3S4QRR0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

985008:EL144 RS09030
gene id: 985008:EL144_RS09030
uniprot id: A0A3S4QC63
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

985008:EL144 RS06455
gene id: 985008:EL144_RS06455
uniprot id: A0A3S4RHY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS07815
gene id: 985008:EL144_RS07815
uniprot id: A0A3S5ECU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

985008:EL144 RS00850
gene id: 985008:EL144_RS00850
uniprot id: A0A3S4Q9X7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

985008:EL144 RS05295
gene id: 985008:EL144_RS05295
uniprot id: A0A448F8Q2
names: Similarity
messages: Belongs to the MreC family.

985008:EL144 RS11090
gene id: 985008:EL144_RS11090
uniprot id: A0A3S4QTE4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

985008:EL144 RS09515
gene id: 985008:EL144_RS09515
uniprot id: A0A448FAU6
names: Function
names: Similarity
messages: Belongs to the carbamoyltransferase HypF family.
messages: Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.

985008:EL144 RS10115
gene id: 985008:EL144_RS10115
uniprot id: A0A448FBT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

985008:EL144 RS04295
gene id: 985008:EL144_RS04295
uniprot id: A0A3S4TZD7
names: Similarity
messages: Belongs to the radical SAM superfamily. KamA family.

985008:EL144 RS07865
gene id: 985008:EL144_RS07865
uniprot id: A0A448FA14
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

985008:EL144 RS07555
gene id: 985008:EL144_RS07555
uniprot id: A0A448F9W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

985008:EL144 RS06815
gene id: 985008:EL144_RS06815
uniprot id: A0A3S4Q5J6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

985008:EL144 RS00190
gene id: 985008:EL144_RS00190
uniprot id: A0A448F641
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08815
gene id: 985008:EL144_RS08815
uniprot id: A0A3S4QSU4
names: Cofactor
names: Function
names: PTM
names: Similarity
messages: Activated by phosphorylation.
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate.

985008:EL144 RS09410
gene id: 985008:EL144_RS09410
uniprot id: A0A448FAT4
names: Similarity
messages: Belongs to the band 7/mec-2 family.

985008:EL144 RS08660
gene id: 985008:EL144_RS08660
uniprot id: A0A3S4QSS8
names: Function
names: Similarity
messages: Belongs to the LpxK family.
messages: Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).

985008:EL144 RS07450
gene id: 985008:EL144_RS07450
uniprot id: A0A448F9V8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HsdR family.
messages: Subunit R is required for both nuclease and ATPase activities, but not for modification.
messages: The type I restriction/modification system is composed of three polypeptides R, M and S.

985008:EL144 RS02500
gene id: 985008:EL144_RS02500
uniprot id: A0A3S4PS17
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS06950
gene id: 985008:EL144_RS06950
uniprot id: A0A3S4QSB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

985008:EL144 RS05390
gene id: 985008:EL144_RS05390
uniprot id: A0A448F8K0
names: Similarity
messages: Belongs to the nitroreductase family.

985008:EL144 RS04460
gene id: 985008:EL144_RS04460
uniprot id: A0A448F859
names: Caution
names: Function
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.
messages: Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS05910
gene id: 985008:EL144_RS05910
uniprot id: A0A3S5ECS9
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

985008:EL144 RS04330
gene id: 985008:EL144_RS04330
uniprot id: A0A3S4QAT7
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

985008:EL144 RS03025
gene id: 985008:EL144_RS03025
uniprot id: A0A448F7Q7
names: Cofactor
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.

985008:EL144 RS02285
gene id: 985008:EL144_RS02285
uniprot id: A0A3S4Q447
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.

985008:EL144 RS05580
gene id: 985008:EL144_RS05580
uniprot id: A0A3S4PYH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane
messages: Membrane

985008:EL144 RS10765
gene id: 985008:EL144_RS10765
uniprot id: A0A3S4S5E1
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

985008:EL144 RS03925
gene id: 985008:EL144_RS03925
uniprot id: A0A3S4TZ95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

985008:EL144 RS02855
gene id: 985008:EL144_RS02855
uniprot id: A0A448F7M4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

985008:EL144 RS03785
gene id: 985008:EL144_RS03785
uniprot id: A0A3S4RH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

985008:EL144 RS00795
gene id: 985008:EL144_RS00795
uniprot id: A0A448F647
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cell inner membrane
messages: Homodimer.
messages: Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB/RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host.
messages: The transmembrane domain is a dimerization domain.

985008:EL144 RS08225
gene id: 985008:EL144_RS08225
uniprot id: A0A448FAA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Periplasm

985008:EL144 RS04310
gene id: 985008:EL144_RS04310
uniprot id: A0A3S4PY31
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily.
messages: Cell inner membrane
messages: Involved in transporting aromatic amino acids across the cytoplasmic membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

985008:EL144 RS03480
gene id: 985008:EL144_RS03480
uniprot id: A0A3S4PXT7
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

985008:EL144 RS09165
gene id: 985008:EL144_RS09165
uniprot id: A0A3S4Q6B0
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

985008:EL144 RS04495
gene id: 985008:EL144_RS04495
uniprot id: A0A3S4RHC9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07835
gene id: 985008:EL144_RS07835
uniprot id: A0A448FAG1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type IA topoisomerase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

985008:EL144 RS06775
gene id: 985008:EL144_RS06775
uniprot id: A0A448F9F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS06190
gene id: 985008:EL144_RS06190
uniprot id: A0A3S4PT53
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class B bacterial acid phosphatase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homotetramer.
messages: Periplasm

985008:EL144 RS08300
gene id: 985008:EL144_RS08300
uniprot id: A0A448FAN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MatP family.
messages: Cytoplasm
messages: Homodimer.
messages: Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain.

985008:EL144 RS07855
gene id: 985008:EL144_RS07855
uniprot id: A0A448FA30
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

985008:EL144 RS00420
gene id: 985008:EL144_RS00420
uniprot id: A0A3S4PRH5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS08835
gene id: 985008:EL144_RS08835
uniprot id: A0A3S4Q672
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

985008:EL144 RS04400
gene id: 985008:EL144_RS04400
uniprot id: A0A448F801
names: Similarity
messages: Belongs to the UPF0246 family.

985008:EL144 RS01930
gene id: 985008:EL144_RS01930
uniprot id: A0A3S4RGN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

985008:EL144 RS02805
gene id: 985008:EL144_RS02805
uniprot id: A0A3S4PS51
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS03125
gene id: 985008:EL144_RS03125
uniprot id: A0A3S4QR32
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

985008:EL144 RS06795
gene id: 985008:EL144_RS06795
uniprot id: A0A448F9S8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

985008:EL144 RS10905
gene id: 985008:EL144_RS10905
uniprot id: A0A3S4QCN2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DeaD/CsdA subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.

985008:EL144 RS00170
gene id: 985008:EL144_RS00170
uniprot id: A0A3S4TNU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm

985008:EL144 RS04260
gene id: 985008:EL144_RS04260
uniprot id: A0A3S4QAS9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

985008:EL144 RS01515
gene id: 985008:EL144_RS01515
uniprot id: A0A3S4PX96
names: Similarity
messages: Belongs to the UDPGP type 2 family.

985008:EL144 RS07075
gene id: 985008:EL144_RS07075
uniprot id: A0A448FA01
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS03885
gene id: 985008:EL144_RS03885
uniprot id: A0A448F894
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

985008:EL144 RS05925
gene id: 985008:EL144_RS05925
uniprot id: A0A448F8Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
messages: Cytoplasm

985008:EL144 RS01445
gene id: 985008:EL144_RS01445
uniprot id: A0A3S4RGJ2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

985008:EL144 RS02605
gene id: 985008:EL144_RS02605
uniprot id: A0A448F795
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

985008:EL144 RS03265
gene id: 985008:EL144_RS03265
uniprot id: A0A448F7R8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapA family.
messages: Cell inner membrane
messages: Involved in the assembly of lipopolysaccharide (LPS).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS07915
gene id: 985008:EL144_RS07915
uniprot id: A0A448FA27
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08725
gene id: 985008:EL144_RS08725
uniprot id: A0A448FAC9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Heterodimer of an alpha and a beta chain.
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

985008:EL144 RS04145
gene id: 985008:EL144_RS04145
uniprot id: A0A3S4RH87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MenA family. Type 1 subfamily.
messages: Cell membrane
messages: Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).
messages: Membrane

985008:EL144 RS04105
gene id: 985008:EL144_RS04105
uniprot id: A0A448F821
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05125
gene id: 985008:EL144_RS05125
uniprot id: A0A448F913
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.

985008:EL144 RS04505
gene id: 985008:EL144_RS04505
uniprot id: A0A3S4QAV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

985008:EL144 RS03970
gene id: 985008:EL144_RS03970
uniprot id: A0A3S4TPV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

985008:EL144 RS02700
gene id: 985008:EL144_RS02700
uniprot id: A0A3S4PS41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein 1 family.
messages: Periplasm

985008:EL144 RS06195
gene id: 985008:EL144_RS06195
uniprot id: A0A448F942
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

985008:EL144 RS05240
gene id: 985008:EL144_RS05240
uniprot id: A0A448F8G8
names: Function
names: Similarity
messages: Belongs to the RmuC family.
messages: Involved in DNA recombination.

985008:EL144 RS01375
gene id: 985008:EL144_RS01375
uniprot id: A0A448F6P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

985008:EL144 RS03685
gene id: 985008:EL144_RS03685
uniprot id: A0A448F811
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

985008:EL144 RS07605
gene id: 985008:EL144_RS07605
uniprot id: A0A3S4S4G1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

985008:EL144 RS03055
gene id: 985008:EL144_RS03055
uniprot id: A0A3S4QR20
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

985008:EL144 RS10530
gene id: 985008:EL144_RS10530
uniprot id: A0A3S4PUH4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

985008:EL144 RS07205
gene id: 985008:EL144_RS07205
uniprot id: A0A3S4Q5N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

985008:EL144 RS03275
gene id: 985008:EL144_RS03275
uniprot id: A0A448F804
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

985008:EL144 RS07680
gene id: 985008:EL144_RS07680
uniprot id: A0A3S4Q5U0
names: Similarity
messages: Belongs to the YjdM family.

985008:EL144 RS05890
gene id: 985008:EL144_RS05890
uniprot id: A0A448F9B6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07985
gene id: 985008:EL144_RS07985
uniprot id: A0A3S4PZ83
names: Cofactor
names: Similarity
messages: Belongs to the anthranilate synthase component I family.
messages: Binds 1 Mg(2+) ion per subunit.

985008:EL144 RS09730
gene id: 985008:EL144_RS09730
uniprot id: A0A3S5ECW9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

985008:EL144 RS03640
gene id: 985008:EL144_RS03640
uniprot id: A0A448F842
names: Similarity
messages: Belongs to the peptidase U62 family.

985008:EL144 RS05095
gene id: 985008:EL144_RS05095
uniprot id: A0A448F8H6
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

985008:EL144 RS06740
gene id: 985008:EL144_RS06740
uniprot id: A0A3S4QBH6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family.
messages: Cell inner membrane
messages: Membrane
messages: Responsible for the transport of C4-dicarboxylates.

985008:EL144 RS08750
gene id: 985008:EL144_RS08750
uniprot id: A0A448FAK8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 32 family.
messages: Cytoplasm
messages: Enables the bacterium to metabolize sucrose as a sole carbon source.

985008:EL144 RS04865
gene id: 985008:EL144_RS04865
uniprot id: A0A448F8S4
names: Similarity
messages: Belongs to the asparaginase 1 family.

985008:EL144 RS04355
gene id: 985008:EL144_RS04355
uniprot id: A0A448F875
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycyl radical enzyme (GRE) family. PFL subfamily.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS06650
gene id: 985008:EL144_RS06650
uniprot id: A0A3S5ECT6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family. T3SS ATPase subfamily.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

985008:EL144 RS03735
gene id: 985008:EL144_RS03735
uniprot id: A0A3S5ECQ6
names: Similarity
messages: Belongs to the peptidase M17 family.

985008:EL144 RS00800
gene id: 985008:EL144_RS00800
uniprot id: A0A3S4TYF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

985008:EL144 RS03475
gene id: 985008:EL144_RS03475
uniprot id: A0A448F7L0
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS09010
gene id: 985008:EL144_RS09010
uniprot id: A0A448FB10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

985008:EL144 RS02590
gene id: 985008:EL144_RS02590
uniprot id: A0A448F7K5
names: Similarity
messages: Belongs to the glutaredoxin family. Monothiol subfamily.

985008:EL144 RS09235
gene id: 985008:EL144_RS09235
uniprot id: A0A448FB97
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
messages: Binds 3 [4Fe-4S] clusters.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane.
messages: The complex is composed of six subunits: RnfA, RnfB, RnfC, RnfD, RnfE and RnfG.

985008:EL144 RS10060
gene id: 985008:EL144_RS10060
uniprot id: A0A448FBR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TrpR family.
messages: Cytoplasm
messages: Homodimer.
messages: This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription.

985008:EL144 RS07945
gene id: 985008:EL144_RS07945
uniprot id: A0A448FA59
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

985008:EL144 RS08875
gene id: 985008:EL144_RS08875
uniprot id: A0A3S4RIM2
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

985008:EL144 RS10955
gene id: 985008:EL144_RS10955
uniprot id: A0A3S5ECY1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

985008:EL144 RS06165
gene id: 985008:EL144_RS06165
uniprot id: A0A3S4RHV8
names: Similarity
messages: Belongs to the UPF0304 family.

985008:EL144 RS00545
gene id: 985008:EL144_RS00545
uniprot id: A0A3S4TNY4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

985008:EL144 RS08200
gene id: 985008:EL144_RS08200
uniprot id: A0A3S4U0G6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: Binds 1 molybdenum-bis(molybdopterin guanine dinucleotide) (Mo-bis-MGD) cofactor per subunit.
messages: Exported by the Tat system.
messages: Periplasm
messages: Reduces trimethylamine-N-oxide (TMAO) into trimethylamine; an anaerobic reaction coupled to energy-yielding reactions.

985008:EL144 RS00415
gene id: 985008:EL144_RS00415
uniprot id: A0A3S4S2A5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

985008:EL144 RS08175
gene id: 985008:EL144_RS08175
uniprot id: A0A3S4PTT6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

985008:EL144 RS06530
gene id: 985008:EL144_RS06530
uniprot id: A0A3S4QS51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.
messages: Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain.
messages: Cell membrane

985008:EL144 RS09975
gene id: 985008:EL144_RS09975
uniprot id: A0A3S4QCE7
names: Cofactor
names: Similarity
messages: Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.
messages: Binds 1 Fe cation per subunit.
messages: Binds 1 zinc ion per subunit.

985008:EL144 RS02545
gene id: 985008:EL144_RS02545
uniprot id: A0A448F736
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

985008:EL144 RS10175
gene id: 985008:EL144_RS10175
uniprot id: A0A448FB99
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

985008:EL144 RS06800
gene id: 985008:EL144_RS06800
uniprot id: A0A448F9U7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS10285
gene id: 985008:EL144_RS10285
uniprot id: A0A448FBC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methyltransferase superfamily. RsmC family.
messages: Cytoplasm
messages: Monomer.
messages: Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle.

985008:EL144 RS07590
gene id: 985008:EL144_RS07590
uniprot id: A0A3S4QBR0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS00455
gene id: 985008:EL144_RS00455
uniprot id: A0A3S4RG92
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

985008:EL144 RS09495
gene id: 985008:EL144_RS09495
uniprot id: A0A448FBF2
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10525
gene id: 985008:EL144_RS10525
uniprot id: A0A3S4S5C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

985008:EL144 RS03000
gene id: 985008:EL144_RS03000
uniprot id: A0A448F7C6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

985008:EL144 RS07260
gene id: 985008:EL144_RS07260
uniprot id: A0A448F9P2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

985008:EL144 RS06200
gene id: 985008:EL144_RS06200
uniprot id: A0A448F938
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

985008:EL144 RS10445
gene id: 985008:EL144_RS10445
uniprot id: A0A3S4PUG5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS10070
gene id: 985008:EL144_RS10070
uniprot id: A0A448FBA1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

985008:EL144 RS08490
gene id: 985008:EL144_RS08490
uniprot id: A0A448FAV4
names: Similarity
messages: Belongs to the porin LamB (TC 1.B.3) family.

985008:EL144 RS10565
gene id: 985008:EL144_RS10565
uniprot id: A0A448FBI7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

985008:EL144 RS07705
gene id: 985008:EL144_RS07705
uniprot id: A0A3S4S4H1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

985008:EL144 RS04735
gene id: 985008:EL144_RS04735
uniprot id: A0A448F866
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbE subfamily.
messages: Cell inner membrane

985008:EL144 RS05550
gene id: 985008:EL144_RS05550
uniprot id: A0A3S4QRW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

985008:EL144 RS10855
gene id: 985008:EL144_RS10855
uniprot id: A0A448FBL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm
messages: Purine salvage pathway enzyme which catalyzes the transfer of the ribosyl-5-phosphate group from 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to the N9 position of hypoxanthine to yield IMP (inosine 5'-monophosphate). To a lesser extent, can also act on guanine leading to GMP, but shows a highly less efficient activity with xanthine.

985008:EL144 RS07115
gene id: 985008:EL144_RS07115
uniprot id: A0A448F9K1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

985008:EL144 RS04490
gene id: 985008:EL144_RS04490
uniprot id: A0A448F8P7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

985008:EL144 RS02900
gene id: 985008:EL144_RS02900
uniprot id: A0A448F7J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PqiA family.
messages: Membrane

985008:EL144 RS09795
gene id: 985008:EL144_RS09795
uniprot id: A0A3S4S546
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

985008:EL144 RS06875
gene id: 985008:EL144_RS06875
uniprot id: A0A3S4QSA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

985008:EL144 RS00555
gene id: 985008:EL144_RS00555
uniprot id: A0A448F6C0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family. GreB subfamily.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

985008:EL144 RS02185
gene id: 985008:EL144_RS02185
uniprot id: A0A448F7A8
names: Function
names: Similarity
messages: Belongs to the carbohydrate kinase PfkB family.
messages: Catalyzes the ATP-dependent phosphorylation of fructose-l-phosphate to fructose-l,6-bisphosphate.

985008:EL144 RS05840
gene id: 985008:EL144_RS05840
uniprot id: A0A3S4PYK0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

985008:EL144 RS06295
gene id: 985008:EL144_RS06295
uniprot id: A0A448F966
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

985008:EL144 RS10400
gene id: 985008:EL144_RS10400
uniprot id: A0A3S4TRN7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

985008:EL144 RS05085
gene id: 985008:EL144_RS05085
uniprot id: A0A3S4RHJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

985008:EL144 RS00220
gene id: 985008:EL144_RS00220
uniprot id: A0A3S4TY81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

985008:EL144 RS01260
gene id: 985008:EL144_RS01260
uniprot id: A0A448F6D6
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS08165
gene id: 985008:EL144_RS08165
uniprot id: A0A448FA94
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

985008:EL144 RS08060
gene id: 985008:EL144_RS08060
uniprot id: A0A3S4Q5Y4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcdB/MmdB/OadB family.
messages: Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation.
messages: Cell membrane
messages: Heterotrimer of an alpha, a beta and a gamma subunit.
messages: Membrane

985008:EL144 RS05850
gene id: 985008:EL144_RS05850
uniprot id: A0A448F9C2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

985008:EL144 RS04390
gene id: 985008:EL144_RS04390
uniprot id: A0A3S4PY39
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS06620
gene id: 985008:EL144_RS06620
uniprot id: A0A3S4PT97
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

985008:EL144 RS09425
gene id: 985008:EL144_RS09425
uniprot id: A0A448FAV6
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

985008:EL144 RS07230
gene id: 985008:EL144_RS07230
uniprot id: A0A3S4RI60
names: Cofactor
names: Similarity
messages: Belongs to the nitroreductase family.
messages: Binds 1 FMN per subunit.

985008:EL144 RS05555
gene id: 985008:EL144_RS05555
uniprot id: A0A448F8Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits).
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

985008:EL144 RS07060
gene id: 985008:EL144_RS07060
uniprot id: A0A3S4QSC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

985008:EL144 RS01910
gene id: 985008:EL144_RS01910
uniprot id: A0A3S4Q416
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

985008:EL144 RS00340
gene id: 985008:EL144_RS00340
uniprot id: A0A448F5U5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase HII family.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

985008:EL144 RS07400
gene id: 985008:EL144_RS07400
uniprot id: A0A448F9N1
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

985008:EL144 RS02935
gene id: 985008:EL144_RS02935
uniprot id: A0A448F7A5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion.
messages: Homodimer.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

985008:EL144 RS10800
gene id: 985008:EL144_RS10800
uniprot id: A0A3S4Q6R5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
messages: Periplasm

985008:EL144 RS09150
gene id: 985008:EL144_RS09150
uniprot id: A0A3S4QSY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

985008:EL144 RS08470
gene id: 985008:EL144_RS08470
uniprot id: A0A3S5ECV5
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

985008:EL144 RS03880
gene id: 985008:EL144_RS03880
uniprot id: A0A3S4RH64
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

985008:EL144 RS00400
gene id: 985008:EL144_RS00400
uniprot id: A0A448F5X7
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by GTP. Inhibited by UTP.
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

985008:EL144 RS08150
gene id: 985008:EL144_RS08150
uniprot id: A0A3S4QBX8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

985008:EL144 RS04670
gene id: 985008:EL144_RS04670
uniprot id: A0A448F8P5
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS05750
gene id: 985008:EL144_RS05750
uniprot id: A0A3S4PT09
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

985008:EL144 RS08305
gene id: 985008:EL144_RS08305
uniprot id: A0A3S4QBY6
names: Subcellular Location Annotation
messages: Cytoplasm

985008:EL144 RS05875
gene id: 985008:EL144_RS05875
uniprot id: A0A3S4PT24
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL3 family.
messages: Methylated by PrmB.
messages: One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.

985008:EL144 RS05305
gene id: 985008:EL144_RS05305
uniprot id: A0A448F8K1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

985008:EL144 RS01200
gene id: 985008:EL144_RS01200
uniprot id: A0A3S5ECN1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

985008:EL144 RS07465
gene id: 985008:EL144_RS07465
uniprot id: A0A448F9T7
names: Similarity
messages: Belongs to the N(4)/N(6)-methyltransferase family.

985008:EL144 RS07360
gene id: 985008:EL144_RS07360
uniprot id: A0A448F9R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

985008:EL144 RS06905
gene id: 985008:EL144_RS06905
uniprot id: A0A3S4Q5K7
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

985008:EL144 RS06825
gene id: 985008:EL144_RS06825
uniprot id: A0A3S4TQP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

985008:EL144 RS01510
gene id: 985008:EL144_RS01510
uniprot id: A0A448F6H4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MetJ family.
messages: Cytoplasm
messages: Does not bind DNA by a helix-turn-helix motif.
messages: Homodimer.
messages: This regulatory protein, when combined with SAM (S-adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis.

985008:EL144 RS05495
gene id: 985008:EL144_RS05495
uniprot id: A0A3S5ECS5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

985008:EL144 RS08880
gene id: 985008:EL144_RS08880
uniprot id: A0A3S4QC49
names: Subcellular Location Annotation
messages: Membrane

985008:EL144 RS07875
gene id: 985008:EL144_RS07875
uniprot id: A0A448FAD9
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

985008:EL144 RS04100
gene id: 985008:EL144_RS04100
uniprot id: A0A3S4PSH7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the D-alanine--D-alanine ligase family.
messages: Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
messages: In the N-terminal section; belongs to the glutamate--cysteine ligase type 1 family. Type 2 subfamily.
messages: Monomer.
messages: Synthesizes glutathione from L-glutamate and L-cysteine via gamma-L-glutamyl-L-cysteine.