980254:UC8 RS17135
gene id: 980254:UC8_RS17135
uniprot id: A0A5B9R5F7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS26085
gene id: 980254:UC8_RS26085
uniprot id: A0A5B9QZ46
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type A subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Binds the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

980254:UC8 RS18555
gene id: 980254:UC8_RS18555
uniprot id: A0A5B9QUU2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS12295
gene id: 980254:UC8_RS12295
uniprot id: A0A5B9QNB2
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Clade 'B2' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-allosteric.

980254:UC8 RS17430
gene id: 980254:UC8_RS17430
uniprot id: A0A5B9QR49
names: Similarity
messages: Belongs to the UPF0178 family.

980254:UC8 RS01645
gene id: 980254:UC8_RS01645
uniprot id: A0A5B9QMZ4
names: Similarity
messages: Belongs to the phosphohexose mutase family.

980254:UC8 RS24595
gene id: 980254:UC8_RS24595
uniprot id: A0A5B9QYL4
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

980254:UC8 RS18270
gene id: 980254:UC8_RS18270
uniprot id: A0A5B9QWA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS04990
gene id: 980254:UC8_RS04990
uniprot id: A0A5B9QMH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

980254:UC8 RS25440
gene id: 980254:UC8_RS25440
uniprot id: A0A5B9R8I0
names: Similarity
messages: Belongs to the phosphohexose mutase family.

980254:UC8 RS01130
gene id: 980254:UC8_RS01130
uniprot id: A0A5B9QKK6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

980254:UC8 RS19500
gene id: 980254:UC8_RS19500
uniprot id: A0A5B9QVC7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

980254:UC8 RS04470
gene id: 980254:UC8_RS04470
uniprot id: A0A5B9QNA3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FTR family.
messages: Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT).
messages: Cytoplasm
messages: Homotetramer.

980254:UC8 RS17150
gene id: 980254:UC8_RS17150
uniprot id: A0A5B9QVP2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

980254:UC8 RS13645
gene id: 980254:UC8_RS13645
uniprot id: A0A5B9QSP5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

980254:UC8 RS01165
gene id: 980254:UC8_RS01165
uniprot id: A0A5B9QJY7
names: Similarity
messages: Belongs to the UDPGP type 1 family.

980254:UC8 RS22550
gene id: 980254:UC8_RS22550
uniprot id: A0A5B9QXI1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

980254:UC8 RS05355
gene id: 980254:UC8_RS05355
uniprot id: A0A5B9QNS1
names: Similarity
messages: Belongs to the AlaDH/PNT family.

980254:UC8 RS28090
gene id: 980254:UC8_RS28090
uniprot id: A0A5B9QX61
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS12705
gene id: 980254:UC8_RS12705
uniprot id: A0A5B9QT25
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS05245
gene id: 980254:UC8_RS05245
uniprot id: A0A5B9QMM2
names: Similarity
messages: Belongs to the PstS family.

980254:UC8 RS06560
gene id: 980254:UC8_RS06560
uniprot id: A0A5B9QJT6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS26910
gene id: 980254:UC8_RS26910
uniprot id: A0A5B9R9C7
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS11515
gene id: 980254:UC8_RS11515
uniprot id: A0A5B9QMX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

980254:UC8 RS21855
gene id: 980254:UC8_RS21855
uniprot id: A0A5B9R6X6
names: Similarity
messages: Belongs to the peptidase S15 family.

980254:UC8 RS23220
gene id: 980254:UC8_RS23220
uniprot id: A0A5B9QZS3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS24605
gene id: 980254:UC8_RS24605
uniprot id: A0A5B9QY50
names: Similarity
messages: Belongs to the pyruvate kinase family.

980254:UC8 RS08215
gene id: 980254:UC8_RS08215
uniprot id: A0A5B9QP13
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS10525
gene id: 980254:UC8_RS10525
uniprot id: A0A5B9QMC6
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

980254:UC8 RS11265
gene id: 980254:UC8_RS11265
uniprot id: A0A5B9QT90
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

980254:UC8 RS06840
gene id: 980254:UC8_RS06840
uniprot id: A0A5B9QNE2
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS02840
gene id: 980254:UC8_RS02840
uniprot id: A0A5B9QM99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980254:UC8 RS04120
gene id: 980254:UC8_RS04120
uniprot id: A0A5B9QM36
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS01810
gene id: 980254:UC8_RS01810
uniprot id: A0A5B9QKA2
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS27510
gene id: 980254:UC8_RS27510
uniprot id: A0A5B9QWU8
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

980254:UC8 RS04995
gene id: 980254:UC8_RS04995
uniprot id: A0A5B9QYN5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS13225
gene id: 980254:UC8_RS13225
uniprot id: A0A5B9QNS2
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

980254:UC8 RS01580
gene id: 980254:UC8_RS01580
uniprot id: A0A5B9QWP7
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

980254:UC8 RS01805
gene id: 980254:UC8_RS01805
uniprot id: A0A5B9QH77
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

980254:UC8 RS15465
gene id: 980254:UC8_RS15465
uniprot id: A0A5B9QQ66
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

980254:UC8 RS09585
gene id: 980254:UC8_RS09585
uniprot id: A0A5B9QLL3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

980254:UC8 RS20660
gene id: 980254:UC8_RS20660
uniprot id: A0A5B9QXP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

980254:UC8 RS07890
gene id: 980254:UC8_RS07890
uniprot id: A0A5B9R029
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS14285
gene id: 980254:UC8_RS14285
uniprot id: A0A5B9QT15
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

980254:UC8 RS21355
gene id: 980254:UC8_RS21355
uniprot id: A0A5B9R6Q9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

980254:UC8 RS18560
gene id: 980254:UC8_RS18560
uniprot id: A0A5B9R657
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24490
gene id: 980254:UC8_RS24490
uniprot id: A0A5B9QV53
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

980254:UC8 RS28330
gene id: 980254:UC8_RS28330
uniprot id: A0A5B9QZZ8
names: Similarity
messages: Belongs to the asparagine synthetase family.

980254:UC8 RS02030
gene id: 980254:UC8_RS02030
uniprot id: A0A5B9QL21
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

980254:UC8 RS21965
gene id: 980254:UC8_RS21965
uniprot id: A0A5B9R7I1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

980254:UC8 RS00635
gene id: 980254:UC8_RS00635
uniprot id: A0A5B9QKR0
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS24435
gene id: 980254:UC8_RS24435
uniprot id: A0A5B9QV45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

980254:UC8 RS13260
gene id: 980254:UC8_RS13260
uniprot id: A0A5B9QTE5
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

980254:UC8 RS06390
gene id: 980254:UC8_RS06390
uniprot id: A0A5B9QQN9
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980254:UC8 RS23345
gene id: 980254:UC8_RS23345
uniprot id: A0A5B9R819
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

980254:UC8 RS29175
gene id: 980254:UC8_RS29175
uniprot id: A0A5B9R0F3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

980254:UC8 RS28580
gene id: 980254:UC8_RS28580
uniprot id: A0A5B9RA39
names: Similarity
messages: Belongs to the RecJ family.

980254:UC8 RS25150
gene id: 980254:UC8_RS25150
uniprot id: A0A5B9QVI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS02460
gene id: 980254:UC8_RS02460
uniprot id: A0A5B9QLS4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS12735
gene id: 980254:UC8_RS12735
uniprot id: A0A5B9R2S0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS12770
gene id: 980254:UC8_RS12770
uniprot id: A0A5B9QNI4
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS23850
gene id: 980254:UC8_RS23850
uniprot id: A0A5B9QUS3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

980254:UC8 RS01000
gene id: 980254:UC8_RS01000
uniprot id: A0A5B9QML1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

980254:UC8 RS05140
gene id: 980254:UC8_RS05140
uniprot id: A0A5B9QYM1
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

980254:UC8 RS28525
gene id: 980254:UC8_RS28525
uniprot id: A0A5B9R9N1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980254:UC8 RS25675
gene id: 980254:UC8_RS25675
uniprot id: A0A5B9QYY0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

980254:UC8 RS05155
gene id: 980254:UC8_RS05155
uniprot id: A0A5B9QJK1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS23370
gene id: 980254:UC8_RS23370
uniprot id: A0A5B9QUI4
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

980254:UC8 RS13520
gene id: 980254:UC8_RS13520
uniprot id: A0A5B9QUJ9
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

980254:UC8 RS24050
gene id: 980254:UC8_RS24050
uniprot id: A0A5B9QY67
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS01010
gene id: 980254:UC8_RS01010
uniprot id: A0A5B9QGT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980254:UC8 RS19510
gene id: 980254:UC8_RS19510
uniprot id: A0A5B9QSD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

980254:UC8 RS26165
gene id: 980254:UC8_RS26165
uniprot id: A0A5B9R0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980254:UC8 RS16995
gene id: 980254:UC8_RS16995
uniprot id: A0A5B9QQY8
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS01740
gene id: 980254:UC8_RS01740
uniprot id: A0A5B9QLJ6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980254:UC8 RS18050
gene id: 980254:UC8_RS18050
uniprot id: A0A5B9QUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980254:UC8 RS13660
gene id: 980254:UC8_RS13660
uniprot id: A0A5B9R343
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

980254:UC8 RS05635
gene id: 980254:UC8_RS05635
uniprot id: A0A5B9QYW7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24370
gene id: 980254:UC8_RS24370
uniprot id: A0A5B9R8G1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

980254:UC8 RS11030
gene id: 980254:UC8_RS11030
uniprot id: A0A5B9QRF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

980254:UC8 RS23465
gene id: 980254:UC8_RS23465
uniprot id: A0A5B9QUK4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

980254:UC8 RS21785
gene id: 980254:UC8_RS21785
uniprot id: A0A5B9QTM8
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980254:UC8 RS25335
gene id: 980254:UC8_RS25335
uniprot id: A0A5B9QZ05
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

980254:UC8 RS24400
gene id: 980254:UC8_RS24400
uniprot id: A0A5B9QYC2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS26590
gene id: 980254:UC8_RS26590
uniprot id: A0A5B9R8X0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980254:UC8 RS05440
gene id: 980254:UC8_RS05440
uniprot id: A0A5B9QMQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

980254:UC8 RS07545
gene id: 980254:UC8_RS07545
uniprot id: A0A5B9QPF3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

980254:UC8 RS02815
gene id: 980254:UC8_RS02815
uniprot id: A0A5B9QLY7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

980254:UC8 RS11070
gene id: 980254:UC8_RS11070
uniprot id: A0A5B9QMB3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS22180
gene id: 980254:UC8_RS22180
uniprot id: A0A5B9R7K8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

980254:UC8 RS19725
gene id: 980254:UC8_RS19725
uniprot id: A0A5B9QS80
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. CpsB/CapC family.

980254:UC8 RS23755
gene id: 980254:UC8_RS23755
uniprot id: A0A5B9QY24
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

980254:UC8 RS21000
gene id: 980254:UC8_RS21000
uniprot id: A0A5B9QW61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980254:UC8 RS21635
gene id: 980254:UC8_RS21635
uniprot id: A0A5B9QTJ7
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.

980254:UC8 RS09590
gene id: 980254:UC8_RS09590
uniprot id: A0A5B9QLR4
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

980254:UC8 RS07455
gene id: 980254:UC8_RS07455
uniprot id: A0A5B9QZU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

980254:UC8 RS13160
gene id: 980254:UC8_RS13160
uniprot id: A0A5B9QTC2
names: Similarity
messages: Belongs to the VgrG protein family.

980254:UC8 RS21040
gene id: 980254:UC8_RS21040
uniprot id: A0A5B9QWP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
messages: Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.
messages: Cytoplasm

980254:UC8 RS23065
gene id: 980254:UC8_RS23065
uniprot id: A0A5B9R7Y3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

980254:UC8 RS27435
gene id: 980254:UC8_RS27435
uniprot id: A0A5B9QZT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

980254:UC8 RS12635
gene id: 980254:UC8_RS12635
uniprot id: A0A5B9R2P9
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

980254:UC8 RS13665
gene id: 980254:UC8_RS13665
uniprot id: A0A5B9QP63
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

980254:UC8 RS26770
gene id: 980254:UC8_RS26770
uniprot id: A0A5B9R0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

980254:UC8 RS04330
gene id: 980254:UC8_RS04330
uniprot id: A0A5B9QPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

980254:UC8 RS13220
gene id: 980254:UC8_RS13220
uniprot id: A0A5B9QNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

980254:UC8 RS26190
gene id: 980254:UC8_RS26190
uniprot id: A0A5B9QZE4
names: Similarity
messages: Belongs to the bacterial secretin family.

980254:UC8 RS23995
gene id: 980254:UC8_RS23995
uniprot id: A0A5B9QUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

980254:UC8 RS24010
gene id: 980254:UC8_RS24010
uniprot id: A0A5B9QYA4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the QueC family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the ATP-dependent conversion of 7-carboxy-7-deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).

980254:UC8 RS18550
gene id: 980254:UC8_RS18550
uniprot id: A0A5B9R5D9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS04680
gene id: 980254:UC8_RS04680
uniprot id: A0A5B9QNE1
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

980254:UC8 RS19655
gene id: 980254:UC8_RS19655
uniprot id: A0A5B9R6L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

980254:UC8 RS28160
gene id: 980254:UC8_RS28160
uniprot id: A0A5B9QXB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

980254:UC8 RS09740
gene id: 980254:UC8_RS09740
uniprot id: A0A5B9QPZ5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

980254:UC8 RS17695
gene id: 980254:UC8_RS17695
uniprot id: A0A5B9QUT9
names: Function
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

980254:UC8 RS25030
gene id: 980254:UC8_RS25030
uniprot id: A0A5B9QYU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

980254:UC8 RS23315
gene id: 980254:UC8_RS23315
uniprot id: A0A5B9QUF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

980254:UC8 RS07220
gene id: 980254:UC8_RS07220
uniprot id: A0A5B9QPP3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

980254:UC8 RS22955
gene id: 980254:UC8_RS22955
uniprot id: A0A5B9QX66
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

980254:UC8 RS01895
gene id: 980254:UC8_RS01895
uniprot id: A0A5B9QLM4
names: Similarity
messages: Belongs to the glutamine synthetase family.

980254:UC8 RS12520
gene id: 980254:UC8_RS12520
uniprot id: A0A5B9QND7
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS28365
gene id: 980254:UC8_RS28365
uniprot id: A0A5B9R0F1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

980254:UC8 RS15870
gene id: 980254:UC8_RS15870
uniprot id: A0A5B9QQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980254:UC8 RS07050
gene id: 980254:UC8_RS07050
uniprot id: A0A5B9QP66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

980254:UC8 RS27170
gene id: 980254:UC8_RS27170
uniprot id: A0A5B9QZQ0
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.

980254:UC8 RS11420
gene id: 980254:UC8_RS11420
uniprot id: A0A5B9QQZ3
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

980254:UC8 RS27720
gene id: 980254:UC8_RS27720
uniprot id: A0A5B9QX12
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980254:UC8 RS15980
gene id: 980254:UC8_RS15980
uniprot id: A0A5B9QQD6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS20765
gene id: 980254:UC8_RS20765
uniprot id: A0A5B9QXQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS18845
gene id: 980254:UC8_RS18845
uniprot id: A0A5B9QUX9
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS25320
gene id: 980254:UC8_RS25320
uniprot id: A0A5B9QVK8
names: Similarity
messages: Belongs to the Dps family.

980254:UC8 RS16015
gene id: 980254:UC8_RS16015
uniprot id: A0A5B9QV36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrF family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.

980254:UC8 RS03560
gene id: 980254:UC8_RS03560
uniprot id: A0A5B9QMB6
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

980254:UC8 RS09025
gene id: 980254:UC8_RS09025
uniprot id: A0A5B9R0V1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS04190
gene id: 980254:UC8_RS04190
uniprot id: A0A5B9QIP5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980254:UC8 RS06005
gene id: 980254:UC8_RS06005
uniprot id: A0A5B9QQF1
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

980254:UC8 RS06870
gene id: 980254:UC8_RS06870
uniprot id: A0A5B9QK28
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

980254:UC8 RS22365
gene id: 980254:UC8_RS22365
uniprot id: A0A5B9QX63
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

980254:UC8 RS05670
gene id: 980254:UC8_RS05670
uniprot id: A0A5B9QJH0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS27290
gene id: 980254:UC8_RS27290
uniprot id: A0A5B9R958
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980254:UC8 RS24315
gene id: 980254:UC8_RS24315
uniprot id: A0A5B9QXY4
names: Similarity
messages: Belongs to the MotB family.

980254:UC8 RS21675
gene id: 980254:UC8_RS21675
uniprot id: A0A5B9QYW2
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

980254:UC8 RS02995
gene id: 980254:UC8_RS02995
uniprot id: A0A5B9QHR0
names: Similarity
messages: Belongs to the asparagine synthetase family.

980254:UC8 RS11035
gene id: 980254:UC8_RS11035
uniprot id: A0A5B9R200
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

980254:UC8 RS27350
gene id: 980254:UC8_RS27350
uniprot id: A0A5B9R9I8
names: Similarity
messages: Belongs to the SAICAR synthetase family.

980254:UC8 RS22380
gene id: 980254:UC8_RS22380
uniprot id: A0A5B9QWV9
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

980254:UC8 RS16260
gene id: 980254:UC8_RS16260
uniprot id: A0A5B9R4B8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS16415
gene id: 980254:UC8_RS16415
uniprot id: A0A5B9QTN0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS12825
gene id: 980254:UC8_RS12825
uniprot id: A0A5B9QNJ2
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

980254:UC8 RS14775
gene id: 980254:UC8_RS14775
uniprot id: A0A5B9QST2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

980254:UC8 RS20455
gene id: 980254:UC8_RS20455
uniprot id: A0A5B9QSL0
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

980254:UC8 RS07535
gene id: 980254:UC8_RS07535
uniprot id: A0A5B9QKF5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

980254:UC8 RS03405
gene id: 980254:UC8_RS03405
uniprot id: A0A5B9QM82
names: Function
names: Similarity
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

980254:UC8 RS07460
gene id: 980254:UC8_RS07460
uniprot id: A0A5B9QKV8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

980254:UC8 RS17790
gene id: 980254:UC8_RS17790
uniprot id: A0A5B9QUD6
names: Subunit
messages: Homodimer.

980254:UC8 RS23320
gene id: 980254:UC8_RS23320
uniprot id: A0A5B9QUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

980254:UC8 RS06865
gene id: 980254:UC8_RS06865
uniprot id: A0A5B9QJY1
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

980254:UC8 RS22770
gene id: 980254:UC8_RS22770
uniprot id: A0A5B9QYU0
names: Similarity
messages: Belongs to the DEAD box helicase family.

980254:UC8 RS03505
gene id: 980254:UC8_RS03505
uniprot id: A0A5B9QL69
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

980254:UC8 RS18100
gene id: 980254:UC8_RS18100
uniprot id: A0A5B9QUI6
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

980254:UC8 RS28205
gene id: 980254:UC8_RS28205
uniprot id: A0A5B9QXB8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980254:UC8 RS20865
gene id: 980254:UC8_RS20865
uniprot id: A0A5B9QXS7
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

980254:UC8 RS22020
gene id: 980254:UC8_RS22020
uniprot id: A0A5B9QTS6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

980254:UC8 RS16795
gene id: 980254:UC8_RS16795
uniprot id: A0A5B9QVG8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS23970
gene id: 980254:UC8_RS23970
uniprot id: A0A5B9QXS5
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

980254:UC8 RS25700
gene id: 980254:UC8_RS25700
uniprot id: A0A5B9QVU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Membrane

980254:UC8 RS13040
gene id: 980254:UC8_RS13040
uniprot id: A0A5B9R2Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Membrane

980254:UC8 RS17845
gene id: 980254:UC8_RS17845
uniprot id: A0A5B9QUW3
names: Similarity
messages: Belongs to the aspartokinase family.

980254:UC8 RS19535
gene id: 980254:UC8_RS19535
uniprot id: A0A5B9QVJ2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

980254:UC8 RS24000
gene id: 980254:UC8_RS24000
uniprot id: A0A5B9QUV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

980254:UC8 RS17260
gene id: 980254:UC8_RS17260
uniprot id: A0A5B9QWI1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980254:UC8 RS14830
gene id: 980254:UC8_RS14830
uniprot id: A0A5B9QTC6
names: Similarity
messages: Belongs to the IlvD/Edd family.

980254:UC8 RS28800
gene id: 980254:UC8_RS28800
uniprot id: A0A5B9QXP7
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

980254:UC8 RS22650
gene id: 980254:UC8_RS22650
uniprot id: A0A5B9QXK1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

980254:UC8 RS22945
gene id: 980254:UC8_RS22945
uniprot id: A0A5B9QXR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

980254:UC8 RS25225
gene id: 980254:UC8_RS25225
uniprot id: A0A5B9QVJ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

980254:UC8 RS09895
gene id: 980254:UC8_RS09895
uniprot id: A0A5B9R1E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

980254:UC8 RS07745
gene id: 980254:UC8_RS07745
uniprot id: A0A5B9QL06
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

980254:UC8 RS15650
gene id: 980254:UC8_RS15650
uniprot id: A0A5B9QTB4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

980254:UC8 RS05220
gene id: 980254:UC8_RS05220
uniprot id: A0A5B9QJ18
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

980254:UC8 RS25240
gene id: 980254:UC8_RS25240
uniprot id: A0A5B9R8G0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS22655
gene id: 980254:UC8_RS22655
uniprot id: A0A5B9R7A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

980254:UC8 RS15570
gene id: 980254:UC8_RS15570
uniprot id: A0A5B9QQ81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

980254:UC8 RS13670
gene id: 980254:UC8_RS13670
uniprot id: A0A5B9QTM4
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

980254:UC8 RS15840
gene id: 980254:UC8_RS15840
uniprot id: A0A5B9QQA5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980254:UC8 RS01235
gene id: 980254:UC8_RS01235
uniprot id: A0A5B9QWH2
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS25645
gene id: 980254:UC8_RS25645
uniprot id: A0A5B9QYN3
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

980254:UC8 RS02410
gene id: 980254:UC8_RS02410
uniprot id: A0A5B9QLR3
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

980254:UC8 RS04745
gene id: 980254:UC8_RS04745
uniprot id: A0A5B9QLU8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS06860
gene id: 980254:UC8_RS06860
uniprot id: A0A5B9QQV2
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

980254:UC8 RS24525
gene id: 980254:UC8_RS24525
uniprot id: A0A5B9QZR1
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

980254:UC8 RS24245
gene id: 980254:UC8_RS24245
uniprot id: A0A5B9QV02
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS02505
gene id: 980254:UC8_RS02505
uniprot id: A0A5B9QKN7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

980254:UC8 RS04110
gene id: 980254:UC8_RS04110
uniprot id: A0A5B9QMN3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
messages: Homodimer.

980254:UC8 RS24850
gene id: 980254:UC8_RS24850
uniprot id: A0A5B9QVD1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS20385
gene id: 980254:UC8_RS20385
uniprot id: A0A5B9QSW3
names: Similarity
messages: Belongs to the glutathione peroxidase family.

980254:UC8 RS22255
gene id: 980254:UC8_RS22255
uniprot id: A0A5B9QTV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

980254:UC8 RS13215
gene id: 980254:UC8_RS13215
uniprot id: A0A5B9QUE1
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

980254:UC8 RS18725
gene id: 980254:UC8_RS18725
uniprot id: A0A5B9QXA7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

980254:UC8 RS08390
gene id: 980254:UC8_RS08390
uniprot id: A0A5B9QP97
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

980254:UC8 RS21755
gene id: 980254:UC8_RS21755
uniprot id: A0A5B9QWJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

980254:UC8 RS26250
gene id: 980254:UC8_RS26250
uniprot id: A0A5B9R939
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

980254:UC8 RS16940
gene id: 980254:UC8_RS16940
uniprot id: A0A5B9R5B1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

980254:UC8 RS01315
gene id: 980254:UC8_RS01315
uniprot id: A0A5B9QK13
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS00430
gene id: 980254:UC8_RS00430
uniprot id: A0A5B9QM80
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS11015
gene id: 980254:UC8_RS11015
uniprot id: A0A5B9QMA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

980254:UC8 RS10840
gene id: 980254:UC8_RS10840
uniprot id: A0A5B9QQL3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS23455
gene id: 980254:UC8_RS23455
uniprot id: A0A5B9QZW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS23265
gene id: 980254:UC8_RS23265
uniprot id: A0A5B9QZ27
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS17190
gene id: 980254:UC8_RS17190
uniprot id: A0A5B9QU38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980254:UC8 RS04730
gene id: 980254:UC8_RS04730
uniprot id: A0A5B9QPQ3
names: Subcellular Location Annotation
messages: Nucleus

980254:UC8 RS01230
gene id: 980254:UC8_RS01230
uniprot id: A0A5B9QKN0
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS20740
gene id: 980254:UC8_RS20740
uniprot id: A0A5B9R6I3
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

980254:UC8 RS22265
gene id: 980254:UC8_RS22265
uniprot id: A0A5B9QXC5
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

980254:UC8 RS07500
gene id: 980254:UC8_RS07500
uniprot id: A0A5B9QZV2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

980254:UC8 RS08185
gene id: 980254:UC8_RS08185
uniprot id: A0A5B9R081
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS07490
gene id: 980254:UC8_RS07490
uniprot id: A0A5B9QNL4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

980254:UC8 RS19805
gene id: 980254:UC8_RS19805
uniprot id: A0A5B9QSK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Periplasm

980254:UC8 RS23610
gene id: 980254:UC8_RS23610
uniprot id: A0A5B9QUN4
names: Similarity
messages: Belongs to the FlgD family.

980254:UC8 RS01080
gene id: 980254:UC8_RS01080
uniprot id: A0A5B9QKJ6
names: Similarity
messages: Belongs to the glycosyl hydrolase 130 family.

980254:UC8 RS22895
gene id: 980254:UC8_RS22895
uniprot id: A0A5B9QXH9
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

980254:UC8 RS14605
gene id: 980254:UC8_RS14605
uniprot id: A0A5B9QPR2
names: Similarity
messages: Belongs to the Nth/MutY family.

980254:UC8 RS17870
gene id: 980254:UC8_RS17870
uniprot id: A0A5B9QRF9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS23905
gene id: 980254:UC8_RS23905
uniprot id: A0A5B9QY43
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 3 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

980254:UC8 RS06105
gene id: 980254:UC8_RS06105
uniprot id: A0A5B9QJQ6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS23615
gene id: 980254:UC8_RS23615
uniprot id: A0A5B9QXY7
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

980254:UC8 RS24895
gene id: 980254:UC8_RS24895
uniprot id: A0A5B9R8N3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS25590
gene id: 980254:UC8_RS25590
uniprot id: A0A5B9QYM5
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

980254:UC8 RS18700
gene id: 980254:UC8_RS18700
uniprot id: A0A5B9R5G3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS07510
gene id: 980254:UC8_RS07510
uniprot id: A0A5B9QZW2
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

980254:UC8 RS10480
gene id: 980254:UC8_RS10480
uniprot id: A0A5B9QQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

980254:UC8 RS07625
gene id: 980254:UC8_RS07625
uniprot id: A0A5B9QKH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

980254:UC8 RS23310
gene id: 980254:UC8_RS23310
uniprot id: A0A5B9QZT6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

980254:UC8 RS06975
gene id: 980254:UC8_RS06975
uniprot id: A0A5B9QKL6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS01695
gene id: 980254:UC8_RS01695
uniprot id: A0A5B9QN07
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS23690
gene id: 980254:UC8_RS23690
uniprot id: A0A5B9R018
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Requires K(+) for maximal activity.
messages: Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.

980254:UC8 RS09610
gene id: 980254:UC8_RS09610
uniprot id: A0A5B9QPX7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS15795
gene id: 980254:UC8_RS15795
uniprot id: A0A5B9QTA9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS19820
gene id: 980254:UC8_RS19820
uniprot id: A0A5B9QS97
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

980254:UC8 RS25365
gene id: 980254:UC8_RS25365
uniprot id: A0A5B9R0Y8
names: Similarity
messages: Belongs to the DtxR/MntR family.

980254:UC8 RS12655
gene id: 980254:UC8_RS12655
uniprot id: A0A5B9QT17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980254:UC8 RS21770
gene id: 980254:UC8_RS21770
uniprot id: A0A5B9QYA2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

980254:UC8 RS02880
gene id: 980254:UC8_RS02880
uniprot id: A0A5B9QLF1
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS17365
gene id: 980254:UC8_RS17365
uniprot id: A0A5B9QVT6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980254:UC8 RS23275
gene id: 980254:UC8_RS23275
uniprot id: A0A5B9QUE0
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

980254:UC8 RS12810
gene id: 980254:UC8_RS12810
uniprot id: A0A5B9QT43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 2 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

980254:UC8 RS29720
gene id: 980254:UC8_RS29720
uniprot id: A0A5B9QG94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

980254:UC8 RS13315
gene id: 980254:UC8_RS13315
uniprot id: A0A5B9QTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

980254:UC8 RS19610
gene id: 980254:UC8_RS19610
uniprot id: A0A5B9QSF8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

980254:UC8 RS11675
gene id: 980254:UC8_RS11675
uniprot id: A0A5B9QR39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

980254:UC8 RS12555
gene id: 980254:UC8_RS12555
uniprot id: A0A5B9QN65
names: Similarity
messages: Belongs to the intimin/invasin family.

980254:UC8 RS17560
gene id: 980254:UC8_RS17560
uniprot id: A0A5B9QRA1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS20395
gene id: 980254:UC8_RS20395
uniprot id: A0A5B9QY93
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS21105
gene id: 980254:UC8_RS21105
uniprot id: A0A5B9QT88
names: Subcellular Location Annotation
messages: Periplasm

980254:UC8 RS17840
gene id: 980254:UC8_RS17840
uniprot id: A0A5B9QUE3
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

980254:UC8 RS08465
gene id: 980254:UC8_RS08465
uniprot id: A0A5B9QKU6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

980254:UC8 RS26520
gene id: 980254:UC8_RS26520
uniprot id: A0A5B9R1N3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS24540
gene id: 980254:UC8_RS24540
uniprot id: A0A5B9QV64
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

980254:UC8 RS07765
gene id: 980254:UC8_RS07765
uniprot id: A0A5B9QKK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

980254:UC8 RS04175
gene id: 980254:UC8_RS04175
uniprot id: A0A5B9QN39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS24085
gene id: 980254:UC8_RS24085
uniprot id: A0A5B9R088
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IspF family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homotrimer.
messages: Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS02130
gene id: 980254:UC8_RS02130
uniprot id: A0A5B9QX06
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

980254:UC8 RS15480
gene id: 980254:UC8_RS15480
uniprot id: A0A5B9QPV2
names: Similarity
messages: Belongs to the Nudix hydrolase family.

980254:UC8 RS15730
gene id: 980254:UC8_RS15730
uniprot id: A0A5B9QPZ6
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

980254:UC8 RS20590
gene id: 980254:UC8_RS20590
uniprot id: A0A5B9R6Z1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

980254:UC8 RS14350
gene id: 980254:UC8_RS14350
uniprot id: A0A5B9R3J2
names: Similarity
messages: Belongs to the MYG1 family.

980254:UC8 RS23875
gene id: 980254:UC8_RS23875
uniprot id: A0A5B9R890
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS13845
gene id: 980254:UC8_RS13845
uniprot id: A0A5B9R3A2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24660
gene id: 980254:UC8_RS24660
uniprot id: A0A5B9R8K0
names: Similarity
messages: Belongs to the ribF family.

980254:UC8 RS20370
gene id: 980254:UC8_RS20370
uniprot id: A0A5B9QWD3
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

980254:UC8 RS08540
gene id: 980254:UC8_RS08540
uniprot id: A0A5B9QLD2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS27340
gene id: 980254:UC8_RS27340
uniprot id: A0A5B9R967
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS18200
gene id: 980254:UC8_RS18200
uniprot id: A0A5B9R587
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

980254:UC8 RS12680
gene id: 980254:UC8_RS12680
uniprot id: A0A5B9QS74
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS27365
gene id: 980254:UC8_RS27365
uniprot id: A0A5B9R235
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS03230
gene id: 980254:UC8_RS03230
uniprot id: A0A5B9QII8
names: Similarity
messages: Belongs to the LDH/MDH superfamily.

980254:UC8 RS07475
gene id: 980254:UC8_RS07475
uniprot id: A0A5B9QK98
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

980254:UC8 RS11625
gene id: 980254:UC8_RS11625
uniprot id: A0A5B9QR29
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

980254:UC8 RS25925
gene id: 980254:UC8_RS25925
uniprot id: A0A5B9R1C1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lactate permease family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Uptake of L-lactate across the membrane. Can also transport D-lactate and glycolate.

980254:UC8 RS12440
gene id: 980254:UC8_RS12440
uniprot id: A0A5B9QRE2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

980254:UC8 RS27455
gene id: 980254:UC8_RS27455
uniprot id: A0A5B9R9K2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

980254:UC8 RS21970
gene id: 980254:UC8_RS21970
uniprot id: A0A5B9QTR6
names: Similarity
messages: Belongs to the fructosamine kinase family.

980254:UC8 RS16700
gene id: 980254:UC8_RS16700
uniprot id: A0A5B9QW78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS19925
gene id: 980254:UC8_RS19925
uniprot id: A0A5B9QSM2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS23280
gene id: 980254:UC8_RS23280
uniprot id: A0A5B9QUF5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Homohexamer. Forms a ring that surrounds DNA.
messages: Membrane

980254:UC8 RS26890
gene id: 980254:UC8_RS26890
uniprot id: A0A5B9QZK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

980254:UC8 RS28985
gene id: 980254:UC8_RS28985
uniprot id: A0A5B9QXN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

980254:UC8 RS16860
gene id: 980254:UC8_RS16860
uniprot id: A0A5B9QQU0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

980254:UC8 RS28755
gene id: 980254:UC8_RS28755
uniprot id: A0A5B9QXN7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS17125
gene id: 980254:UC8_RS17125
uniprot id: A0A5B9R4P1
names: Similarity
messages: Belongs to the LacAB/RpiB family.

980254:UC8 RS28245
gene id: 980254:UC8_RS28245
uniprot id: A0A5B9R1J8
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

980254:UC8 RS18390
gene id: 980254:UC8_RS18390
uniprot id: A0A5B9QRN2
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

980254:UC8 RS05745
gene id: 980254:UC8_RS05745
uniprot id: A0A5B9QZ09
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

980254:UC8 RS25655
gene id: 980254:UC8_RS25655
uniprot id: A0A5B9QVS9
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.
messages: Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.

980254:UC8 RS18830
gene id: 980254:UC8_RS18830
uniprot id: A0A5B9QXD2
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

980254:UC8 RS16000
gene id: 980254:UC8_RS16000
uniprot id: A0A5B9QTI0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980254:UC8 RS17300
gene id: 980254:UC8_RS17300
uniprot id: A0A5B9QR52
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20790
gene id: 980254:UC8_RS20790
uniprot id: A0A5B9QWK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

980254:UC8 RS07245
gene id: 980254:UC8_RS07245
uniprot id: A0A5B9QP99
names: Similarity
messages: Belongs to the peptidase A24 family.

980254:UC8 RS16730
gene id: 980254:UC8_RS16730
uniprot id: A0A5B9QTX0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS13330
gene id: 980254:UC8_RS13330
uniprot id: A0A5B9QNU1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS26570
gene id: 980254:UC8_RS26570
uniprot id: A0A5B9QWF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

980254:UC8 RS07530
gene id: 980254:UC8_RS07530
uniprot id: A0A5B9QKA7
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

980254:UC8 RS07805
gene id: 980254:UC8_RS07805
uniprot id: A0A5B9QRD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell membrane
messages: Membrane

980254:UC8 RS15820
gene id: 980254:UC8_RS15820
uniprot id: A0A5B9QQD0
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

980254:UC8 RS16875
gene id: 980254:UC8_RS16875
uniprot id: A0A5B9QUE9
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

980254:UC8 RS23335
gene id: 980254:UC8_RS23335
uniprot id: A0A5B9R7K2
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Feedback inhibited by histidine.

980254:UC8 RS01875
gene id: 980254:UC8_RS01875
uniprot id: A0A5B9QWU9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M15D family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.

980254:UC8 RS04200
gene id: 980254:UC8_RS04200
uniprot id: A0A5B9QMQ5
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20020
gene id: 980254:UC8_RS20020
uniprot id: A0A5B9R6R0
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

980254:UC8 RS02105
gene id: 980254:UC8_RS02105
uniprot id: A0A5B9QH78
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS25345
gene id: 980254:UC8_RS25345
uniprot id: A0A5B9QYI3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS07360
gene id: 980254:UC8_RS07360
uniprot id: A0A5B9QZS4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

980254:UC8 RS17745
gene id: 980254:UC8_RS17745
uniprot id: A0A5B9QUU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

980254:UC8 RS03070
gene id: 980254:UC8_RS03070
uniprot id: A0A5B9QLI8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980254:UC8 RS18685
gene id: 980254:UC8_RS18685
uniprot id: A0A5B9QRU0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS21865
gene id: 980254:UC8_RS21865
uniprot id: A0A5B9R7G6
names: Similarity
messages: Belongs to the DapA family.

980254:UC8 RS14310
gene id: 980254:UC8_RS14310
uniprot id: A0A5B9QU08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS24795
gene id: 980254:UC8_RS24795
uniprot id: A0A5B9QY89
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

980254:UC8 RS01255
gene id: 980254:UC8_RS01255
uniprot id: A0A5B9QGT0
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

980254:UC8 RS22245
gene id: 980254:UC8_RS22245
uniprot id: A0A5B9QZ59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

980254:UC8 RS14380
gene id: 980254:UC8_RS14380
uniprot id: A0A5B9QSK7
names: Similarity
messages: Belongs to the YciI family.

980254:UC8 RS03805
gene id: 980254:UC8_RS03805
uniprot id: A0A5B9QLC9
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

980254:UC8 RS04885
gene id: 980254:UC8_RS04885
uniprot id: A0A5B9QLX6
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

980254:UC8 RS10240
gene id: 980254:UC8_RS10240
uniprot id: A0A5B9R1B1
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

980254:UC8 RS21140
gene id: 980254:UC8_RS21140
uniprot id: A0A5B9R6M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

980254:UC8 RS00590
gene id: 980254:UC8_RS00590
uniprot id: A0A5B9QVY6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS24765
gene id: 980254:UC8_RS24765
uniprot id: A0A5B9R0N8
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS09255
gene id: 980254:UC8_RS09255
uniprot id: A0A5B9R0U1
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS02185
gene id: 980254:UC8_RS02185
uniprot id: A0A5B9QI10
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer.

980254:UC8 RS01330
gene id: 980254:UC8_RS01330
uniprot id: A0A5B9QKP8
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS14890
gene id: 980254:UC8_RS14890
uniprot id: A0A5B9R3R7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

980254:UC8 RS18075
gene id: 980254:UC8_RS18075
uniprot id: A0A5B9QRJ5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

980254:UC8 RS16010
gene id: 980254:UC8_RS16010
uniprot id: A0A5B9QQG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980254:UC8 RS18030
gene id: 980254:UC8_RS18030
uniprot id: A0A5B9QW45
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

980254:UC8 RS26210
gene id: 980254:UC8_RS26210
uniprot id: A0A5B9QW29
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20720
gene id: 980254:UC8_RS20720
uniprot id: A0A5B9QSR1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS25330
gene id: 980254:UC8_RS25330
uniprot id: A0A5B9QYS6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20850
gene id: 980254:UC8_RS20850
uniprot id: A0A5B9QW41
names: Function
names: Subcellular Location Annotation
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body

980254:UC8 RS00990
gene id: 980254:UC8_RS00990
uniprot id: A0A5B9QHE8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS05720
gene id: 980254:UC8_RS05720
uniprot id: A0A5B9QJI0
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

980254:UC8 RS20830
gene id: 980254:UC8_RS20830
uniprot id: A0A5B9QT41
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

980254:UC8 RS09390
gene id: 980254:UC8_RS09390
uniprot id: A0A5B9QQJ0
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS27900
gene id: 980254:UC8_RS27900
uniprot id: A0A5B9QX19
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS09380
gene id: 980254:UC8_RS09380
uniprot id: A0A5B9QLL8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

980254:UC8 RS14340
gene id: 980254:UC8_RS14340
uniprot id: A0A5B9R3G8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980254:UC8 RS27800
gene id: 980254:UC8_RS27800
uniprot id: A0A5B9R9Q5
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS07730
gene id: 980254:UC8_RS07730
uniprot id: A0A5B9R017
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

980254:UC8 RS24135
gene id: 980254:UC8_RS24135
uniprot id: A0A5B9R0A1
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Monomer.

980254:UC8 RS11570
gene id: 980254:UC8_RS11570
uniprot id: A0A5B9QR18
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase class-2 family.
messages: Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.

980254:UC8 RS23870
gene id: 980254:UC8_RS23870
uniprot id: A0A5B9QXQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS00040
gene id: 980254:UC8_RS00040
uniprot id: A0A5B9QM20
names: Similarity
messages: Belongs to the CFA/CMAS family.

980254:UC8 RS25230
gene id: 980254:UC8_RS25230
uniprot id: A0A5B9QYQ6
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

980254:UC8 RS09370
gene id: 980254:UC8_RS09370
uniprot id: A0A5B9QSA1
names: Caution
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnD subfamily.
messages: Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS15270
gene id: 980254:UC8_RS15270
uniprot id: A0A5B9QUJ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

980254:UC8 RS12505
gene id: 980254:UC8_RS12505
uniprot id: A0A5B9QSZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980254:UC8 RS06525
gene id: 980254:UC8_RS06525
uniprot id: A0A5B9QNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

980254:UC8 RS11045
gene id: 980254:UC8_RS11045
uniprot id: A0A5B9R1P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

980254:UC8 RS22490
gene id: 980254:UC8_RS22490
uniprot id: A0A5B9QTZ4
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

980254:UC8 RS00745
gene id: 980254:UC8_RS00745
uniprot id: A0A5B9QL19
names: Similarity
messages: Belongs to the CobT family.

980254:UC8 RS08330
gene id: 980254:UC8_RS08330
uniprot id: A0A5B9R0B9
names: Similarity
names: Subunit
messages: Belongs to the FliD family.
messages: Homopentamer.

980254:UC8 RS02560
gene id: 980254:UC8_RS02560
uniprot id: A0A5B9QX81
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS13455
gene id: 980254:UC8_RS13455
uniprot id: A0A5B9R309
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

980254:UC8 RS20745
gene id: 980254:UC8_RS20745
uniprot id: A0A5B9QW17
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

980254:UC8 RS12275
gene id: 980254:UC8_RS12275
uniprot id: A0A5B9QNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

980254:UC8 RS01415
gene id: 980254:UC8_RS01415
uniprot id: A0A5B9QK34
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

980254:UC8 RS18710
gene id: 980254:UC8_RS18710
uniprot id: A0A5B9R681
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS02320
gene id: 980254:UC8_RS02320
uniprot id: A0A5B9QX35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

980254:UC8 RS18950
gene id: 980254:UC8_RS18950
uniprot id: A0A5B9R5K2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS09440
gene id: 980254:UC8_RS09440
uniprot id: A0A5B9QQK1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980254:UC8 RS25690
gene id: 980254:UC8_RS25690
uniprot id: A0A5B9QYP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980254:UC8 RS27385
gene id: 980254:UC8_RS27385
uniprot id: A0A5B9QZY2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

980254:UC8 RS27525
gene id: 980254:UC8_RS27525
uniprot id: A0A5B9QWX5
names: Similarity
messages: Belongs to the fabD family.

980254:UC8 RS27795
gene id: 980254:UC8_RS27795
uniprot id: A0A5B9QZQ4
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS03735
gene id: 980254:UC8_RS03735
uniprot id: A0A5B9QMV0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980254:UC8 RS04930
gene id: 980254:UC8_RS04930
uniprot id: A0A5B9QN42
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

980254:UC8 RS25955
gene id: 980254:UC8_RS25955
uniprot id: A0A5B9QYT3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

980254:UC8 RS28165
gene id: 980254:UC8_RS28165
uniprot id: A0A5B9R079
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Cytoplasm

980254:UC8 RS23665
gene id: 980254:UC8_RS23665
uniprot id: A0A5B9R7Q3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS28795
gene id: 980254:UC8_RS28795
uniprot id: A0A5B9QXP0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS00800
gene id: 980254:UC8_RS00800
uniprot id: A0A5B9QMH2
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

980254:UC8 RS07565
gene id: 980254:UC8_RS07565
uniprot id: A0A5B9QPW5
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS01725
gene id: 980254:UC8_RS01725
uniprot id: A0A5B9QKW6
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

980254:UC8 RS02545
gene id: 980254:UC8_RS02545
uniprot id: A0A5B9QHN1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS18445
gene id: 980254:UC8_RS18445
uniprot id: A0A5B9QUQ6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS04075
gene id: 980254:UC8_RS04075
uniprot id: A0A5B9QY63
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

980254:UC8 RS12740
gene id: 980254:UC8_RS12740
uniprot id: A0A5B9QRJ4
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS05100
gene id: 980254:UC8_RS05100
uniprot id: A0A5B9QYQ2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24535
gene id: 980254:UC8_RS24535
uniprot id: A0A5B9QV57
names: Similarity
messages: Belongs to the Nudix hydrolase family.

980254:UC8 RS19030
gene id: 980254:UC8_RS19030
uniprot id: A0A5B9QWQ5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

980254:UC8 RS16935
gene id: 980254:UC8_RS16935
uniprot id: A0A5B9QTZ9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

980254:UC8 RS04115
gene id: 980254:UC8_RS04115
uniprot id: A0A5B9QY44
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

980254:UC8 RS26695
gene id: 980254:UC8_RS26695
uniprot id: A0A5B9R8Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS26495
gene id: 980254:UC8_RS26495
uniprot id: A0A5B9R8V8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24330
gene id: 980254:UC8_RS24330
uniprot id: A0A5B9QZN2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

980254:UC8 RS16165
gene id: 980254:UC8_RS16165
uniprot id: A0A5B9QVY2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS14835
gene id: 980254:UC8_RS14835
uniprot id: A0A5B9R3Q9
names: Similarity
messages: Belongs to the peptidase S41A family.

980254:UC8 RS09275
gene id: 980254:UC8_RS09275
uniprot id: A0A5B9QLE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980254:UC8 RS18800
gene id: 980254:UC8_RS18800
uniprot id: A0A5B9QVD5
names: Similarity
messages: Belongs to the LarC family.

980254:UC8 RS12965
gene id: 980254:UC8_RS12965
uniprot id: A0A5B9QUA1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS14610
gene id: 980254:UC8_RS14610
uniprot id: A0A5B9QU65
names: Function
names: Similarity
messages: Belongs to the catalase family. HPII subfamily.
messages: Serves to protect cells from the toxic effects of hydrogen peroxide.

980254:UC8 RS16035
gene id: 980254:UC8_RS16035
uniprot id: A0A5B9QTZ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

980254:UC8 RS24480
gene id: 980254:UC8_RS24480
uniprot id: A0A5B9R0H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. C-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

980254:UC8 RS03495
gene id: 980254:UC8_RS03495
uniprot id: A0A5B9QI07
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

980254:UC8 RS13895
gene id: 980254:UC8_RS13895
uniprot id: A0A5B9QS66
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS21990
gene id: 980254:UC8_RS21990
uniprot id: A0A5B9QTM7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

980254:UC8 RS10105
gene id: 980254:UC8_RS10105
uniprot id: A0A5B9QSP6
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

980254:UC8 RS12515
gene id: 980254:UC8_RS12515
uniprot id: A0A5B9QN55
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS27515
gene id: 980254:UC8_RS27515
uniprot id: A0A5B9R167
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

980254:UC8 RS20795
gene id: 980254:UC8_RS20795
uniprot id: A0A5B9R6I7
names: Similarity
messages: Belongs to the peptidase C15 family.

980254:UC8 RS03965
gene id: 980254:UC8_RS03965
uniprot id: A0A5B9QY26
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980254:UC8 RS24715
gene id: 980254:UC8_RS24715
uniprot id: A0A5B9QVA4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

980254:UC8 RS02315
gene id: 980254:UC8_RS02315
uniprot id: A0A5B9QLP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

980254:UC8 RS12245
gene id: 980254:UC8_RS12245
uniprot id: A0A5B9QNA5
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS01680
gene id: 980254:UC8_RS01680
uniprot id: A0A5B9QWQ9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

980254:UC8 RS19495
gene id: 980254:UC8_RS19495
uniprot id: A0A5B9R5Y7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

980254:UC8 RS16290
gene id: 980254:UC8_RS16290
uniprot id: A0A5B9QQA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980254:UC8 RS18360
gene id: 980254:UC8_RS18360
uniprot id: A0A5B9QUR2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS08075
gene id: 980254:UC8_RS08075
uniprot id: A0A5B9R072
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS09940
gene id: 980254:UC8_RS09940
uniprot id: A0A5B9QQ47
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980254:UC8 RS29620
gene id: 980254:UC8_RS29620
uniprot id: A0A5B9QSW1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

980254:UC8 RS25495
gene id: 980254:UC8_RS25495
uniprot id: A0A5B9R8V5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS00790
gene id: 980254:UC8_RS00790
uniprot id: A0A5B9QHB0
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

980254:UC8 RS12660
gene id: 980254:UC8_RS12660
uniprot id: A0A5B9QU37
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

980254:UC8 RS28575
gene id: 980254:UC8_RS28575
uniprot id: A0A5B9R042
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

980254:UC8 RS24630
gene id: 980254:UC8_RS24630
uniprot id: A0A5B9QV83
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

980254:UC8 RS07450
gene id: 980254:UC8_RS07450
uniprot id: A0A5B9QNR1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980254:UC8 RS09405
gene id: 980254:UC8_RS09405
uniprot id: A0A5B9R0W6
names: Similarity
messages: Belongs to the peptidase S41A family.

980254:UC8 RS24100
gene id: 980254:UC8_RS24100
uniprot id: A0A5B9QY74
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

980254:UC8 RS02000
gene id: 980254:UC8_RS02000
uniprot id: A0A5B9QN64
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS04595
gene id: 980254:UC8_RS04595
uniprot id: A0A5B9QIW7
names: Similarity
messages: Belongs to the asparagine synthetase family.

980254:UC8 RS08315
gene id: 980254:UC8_RS08315
uniprot id: A0A5B9QKV0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RnpA family.
messages: Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.
messages: RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

980254:UC8 RS15220
gene id: 980254:UC8_RS15220
uniprot id: A0A5B9QUH7
names: Similarity
messages: Belongs to the ArsC family.

980254:UC8 RS05550
gene id: 980254:UC8_RS05550
uniprot id: A0A5B9QJR7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS07540
gene id: 980254:UC8_RS07540
uniprot id: A0A5B9QNM8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

980254:UC8 RS02940
gene id: 980254:UC8_RS02940
uniprot id: A0A5B9QMC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS19530
gene id: 980254:UC8_RS19530
uniprot id: A0A5B9QS89
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS23560
gene id: 980254:UC8_RS23560
uniprot id: A0A5B9QUM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

980254:UC8 RS10245
gene id: 980254:UC8_RS10245
uniprot id: A0A5B9QME5
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

980254:UC8 RS09070
gene id: 980254:UC8_RS09070
uniprot id: A0A5B9QQC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980254:UC8 RS13605
gene id: 980254:UC8_RS13605
uniprot id: A0A5B9R333
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS15380
gene id: 980254:UC8_RS15380
uniprot id: A0A5B9QPS4
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

980254:UC8 RS28440
gene id: 980254:UC8_RS28440
uniprot id: A0A5B9QXD0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

980254:UC8 RS12725
gene id: 980254:UC8_RS12725
uniprot id: A0A5B9QRM5
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS04725
gene id: 980254:UC8_RS04725
uniprot id: A0A5B9QNE8
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

980254:UC8 RS23620
gene id: 980254:UC8_RS23620
uniprot id: A0A5B9QY33
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.

980254:UC8 RS20835
gene id: 980254:UC8_RS20835
uniprot id: A0A5B9QW97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

980254:UC8 RS17740
gene id: 980254:UC8_RS17740
uniprot id: A0A5B9QUC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

980254:UC8 RS15855
gene id: 980254:UC8_RS15855
uniprot id: A0A5B9R454
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

980254:UC8 RS17900
gene id: 980254:UC8_RS17900
uniprot id: A0A5B9QUX2
names: Similarity
messages: Belongs to the threonine aldolase family.

980254:UC8 RS21135
gene id: 980254:UC8_RS21135
uniprot id: A0A5B9QWS1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

980254:UC8 RS11370
gene id: 980254:UC8_RS11370
uniprot id: A0A5B9QQY0
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

980254:UC8 RS22125
gene id: 980254:UC8_RS22125
uniprot id: A0A5B9QWR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

980254:UC8 RS19695
gene id: 980254:UC8_RS19695
uniprot id: A0A5B9R624
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

980254:UC8 RS21505
gene id: 980254:UC8_RS21505
uniprot id: A0A5B9QWE4
names: Similarity
messages: Belongs to the TPP enzyme family.

980254:UC8 RS23705
gene id: 980254:UC8_RS23705
uniprot id: A0A5B9QY12
names: Similarity
messages: Belongs to the DapA family.

980254:UC8 RS00385
gene id: 980254:UC8_RS00385
uniprot id: A0A5B9QGD5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980254:UC8 RS13635
gene id: 980254:UC8_RS13635
uniprot id: A0A5B9QP01
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

980254:UC8 RS22665
gene id: 980254:UC8_RS22665
uniprot id: A0A5B9R7U1
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

980254:UC8 RS09375
gene id: 980254:UC8_RS09375
uniprot id: A0A5B9QLG7
names: Similarity
messages: Belongs to the carotenoid/retinoid oxidoreductase family.

980254:UC8 RS03715
gene id: 980254:UC8_RS03715
uniprot id: A0A5B9QXW7
names: Similarity
messages: Belongs to the peptidase C56 family.

980254:UC8 RS09240
gene id: 980254:UC8_RS09240
uniprot id: A0A5B9R0Y6
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

980254:UC8 RS11270
gene id: 980254:UC8_RS11270
uniprot id: A0A5B9QMH9
names: Similarity
messages: Belongs to the LacAB/RpiB family.

980254:UC8 RS25605
gene id: 980254:UC8_RS25605
uniprot id: A0A5B9QVR9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20180
gene id: 980254:UC8_RS20180
uniprot id: A0A5B9QSR9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS04695
gene id: 980254:UC8_RS04695
uniprot id: A0A5B9QLU4
names: Similarity
messages: Belongs to the bacterial secretin family.

980254:UC8 RS04255
gene id: 980254:UC8_RS04255
uniprot id: A0A5B9QY68
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

980254:UC8 RS04235
gene id: 980254:UC8_RS04235
uniprot id: A0A5B9QIH9
names: Similarity
messages: Belongs to the CbxX/CfxQ family.

980254:UC8 RS10950
gene id: 980254:UC8_RS10950
uniprot id: A0A5B9QMR4
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

980254:UC8 RS09605
gene id: 980254:UC8_RS09605
uniprot id: A0A5B9R194
names: Similarity
messages: Belongs to the peptidase S1C family.

980254:UC8 RS04475
gene id: 980254:UC8_RS04475
uniprot id: A0A5B9QPL1
names: Similarity
messages: Belongs to the FwdC/FmdC family.

980254:UC8 RS18650
gene id: 980254:UC8_RS18650
uniprot id: A0A5B9R5F5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

980254:UC8 RS03655
gene id: 980254:UC8_RS03655
uniprot id: A0A5B9QL96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

980254:UC8 RS14510
gene id: 980254:UC8_RS14510
uniprot id: A0A5B9QU41
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS09250
gene id: 980254:UC8_RS09250
uniprot id: A0A5B9QPR0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

980254:UC8 RS22700
gene id: 980254:UC8_RS22700
uniprot id: A0A5B9R7A8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

980254:UC8 RS10545
gene id: 980254:UC8_RS10545
uniprot id: A0A5B9QQG0
names: Similarity
messages: Belongs to the DSD1 family.

980254:UC8 RS18265
gene id: 980254:UC8_RS18265
uniprot id: A0A5B9QRN1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

980254:UC8 RS25710
gene id: 980254:UC8_RS25710
uniprot id: A0A5B9R178
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

980254:UC8 RS24125
gene id: 980254:UC8_RS24125
uniprot id: A0A5B9QUY6
names: Subcellular Location Annotation
messages: Cytoplasm

980254:UC8 RS25575
gene id: 980254:UC8_RS25575
uniprot id: A0A5B9QYW0
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS20240
gene id: 980254:UC8_RS20240
uniprot id: A0A5B9QXG3
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

980254:UC8 RS24090
gene id: 980254:UC8_RS24090
uniprot id: A0A5B9QUV6
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980254:UC8 RS08675
gene id: 980254:UC8_RS08675
uniprot id: A0A5B9R0J7
names: Similarity
messages: Belongs to the peptidase A24 family.

980254:UC8 RS18070
gene id: 980254:UC8_RS18070
uniprot id: A0A5B9R5V5
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

980254:UC8 RS11645
gene id: 980254:UC8_RS11645
uniprot id: A0A5B9R212
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

980254:UC8 RS07860
gene id: 980254:UC8_RS07860
uniprot id: A0A5B9QKI1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS11050
gene id: 980254:UC8_RS11050
uniprot id: A0A5B9QMS8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

980254:UC8 RS07720
gene id: 980254:UC8_RS07720
uniprot id: A0A5B9QNR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS04080
gene id: 980254:UC8_RS04080
uniprot id: A0A5B9QIZ6
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

980254:UC8 RS21120
gene id: 980254:UC8_RS21120
uniprot id: A0A5B9QT55
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS05445
gene id: 980254:UC8_RS05445
uniprot id: A0A5B9QYV0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980254:UC8 RS22780
gene id: 980254:UC8_RS22780
uniprot id: A0A5B9QU29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

980254:UC8 RS16240
gene id: 980254:UC8_RS16240
uniprot id: A0A5B9QQ94
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS23785
gene id: 980254:UC8_RS23785
uniprot id: A0A5B9QZC4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

980254:UC8 RS09225
gene id: 980254:UC8_RS09225
uniprot id: A0A5B9QLI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Membrane

980254:UC8 RS07365
gene id: 980254:UC8_RS07365
uniprot id: A0A5B9QKU1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

980254:UC8 RS00020
gene id: 980254:UC8_RS00020
uniprot id: A0A5B9QK02
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

980254:UC8 RS07125
gene id: 980254:UC8_RS07125
uniprot id: A0A5B9QPM4
names: Similarity
messages: Belongs to the DNase I family.

980254:UC8 RS04245
gene id: 980254:UC8_RS04245
uniprot id: A0A5B9QLK6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS29030
gene id: 980254:UC8_RS29030
uniprot id: A0A5B9RAA8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

980254:UC8 RS01640
gene id: 980254:UC8_RS01640
uniprot id: A0A5B9QLH9
names: Similarity
messages: Belongs to the phosphohexose mutase family.

980254:UC8 RS26075
gene id: 980254:UC8_RS26075
uniprot id: A0A5B9QW54
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

980254:UC8 RS08340
gene id: 980254:UC8_RS08340
uniprot id: A0A5B9R0A8
names: Similarity
messages: Belongs to the TrpC family.

980254:UC8 RS08890
gene id: 980254:UC8_RS08890
uniprot id: A0A5B9QQX6
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

980254:UC8 RS04830
gene id: 980254:UC8_RS04830
uniprot id: A0A5B9QIT5
names: Similarity
messages: Belongs to the P(II) protein family.

980254:UC8 RS18180
gene id: 980254:UC8_RS18180
uniprot id: A0A5B9QX03
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

980254:UC8 RS00200
gene id: 980254:UC8_RS00200
uniprot id: A0A5B9QGD7
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

980254:UC8 RS11480
gene id: 980254:UC8_RS11480
uniprot id: A0A5B9R280
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

980254:UC8 RS00240
gene id: 980254:UC8_RS00240
uniprot id: A0A5B9QGA8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS02065
gene id: 980254:UC8_RS02065
uniprot id: A0A5B9QKE6
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

980254:UC8 RS01260
gene id: 980254:UC8_RS01260
uniprot id: A0A5B9QGY0
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.

980254:UC8 RS07380
gene id: 980254:UC8_RS07380
uniprot id: A0A5B9QK76
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

980254:UC8 RS17760
gene id: 980254:UC8_RS17760
uniprot id: A0A5B9R5Q6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980254:UC8 RS05165
gene id: 980254:UC8_RS05165
uniprot id: A0A5B9QPY2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24805
gene id: 980254:UC8_RS24805
uniprot id: A0A5B9QVC1
names: Similarity
messages: Belongs to the polysaccharide synthase family.

980254:UC8 RS00615
gene id: 980254:UC8_RS00615
uniprot id: A0A5B9QMC1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS02290
gene id: 980254:UC8_RS02290
uniprot id: A0A5B9QLV5
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.

980254:UC8 RS07855
gene id: 980254:UC8_RS07855
uniprot id: A0A5B9QRD7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS13020
gene id: 980254:UC8_RS13020
uniprot id: A0A5B9QNE0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980254:UC8 RS05310
gene id: 980254:UC8_RS05310
uniprot id: A0A5B9QNR0
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS03815
gene id: 980254:UC8_RS03815
uniprot id: A0A5B9QXZ1
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

980254:UC8 RS24940
gene id: 980254:UC8_RS24940
uniprot id: A0A5B9R8B1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

980254:UC8 RS09985
gene id: 980254:UC8_RS09985
uniprot id: A0A5B9R1G2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS01620
gene id: 980254:UC8_RS01620
uniprot id: A0A5B9QWP8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS15970
gene id: 980254:UC8_RS15970
uniprot id: A0A5B9QVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

980254:UC8 RS21955
gene id: 980254:UC8_RS21955
uniprot id: A0A5B9R6Z4
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS17550
gene id: 980254:UC8_RS17550
uniprot id: A0A5B9QUA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS08325
gene id: 980254:UC8_RS08325
uniprot id: A0A5B9QPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

980254:UC8 RS01975
gene id: 980254:UC8_RS01975
uniprot id: A0A5B9QWW8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS28375
gene id: 980254:UC8_RS28375
uniprot id: A0A5B9R004
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS26035
gene id: 980254:UC8_RS26035
uniprot id: A0A5B9QW03
names: Similarity
messages: Belongs to the SCO1/2 family.

980254:UC8 RS11235
gene id: 980254:UC8_RS11235
uniprot id: A0A5B9QRI4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

980254:UC8 RS15445
gene id: 980254:UC8_RS15445
uniprot id: A0A5B9QTN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

980254:UC8 RS21270
gene id: 980254:UC8_RS21270
uniprot id: A0A5B9QTB8
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

980254:UC8 RS25720
gene id: 980254:UC8_RS25720
uniprot id: A0A5B9QVU7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980254:UC8 RS01100
gene id: 980254:UC8_RS01100
uniprot id: A0A5B9QMN5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980254:UC8 RS05645
gene id: 980254:UC8_RS05645
uniprot id: A0A5B9QYY4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

980254:UC8 RS20390
gene id: 980254:UC8_RS20390
uniprot id: A0A5B9QXJ7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20025
gene id: 980254:UC8_RS20025
uniprot id: A0A5B9QSP8
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

980254:UC8 RS20840
gene id: 980254:UC8_RS20840
uniprot id: A0A5B9QWL5
names: Subcellular Location Annotation
messages: Periplasm

980254:UC8 RS06900
gene id: 980254:UC8_RS06900
uniprot id: A0A5B9QP33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

980254:UC8 RS02400
gene id: 980254:UC8_RS02400
uniprot id: A0A5B9QHJ7
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

980254:UC8 RS16270
gene id: 980254:UC8_RS16270
uniprot id: A0A5B9R4Z1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS00980
gene id: 980254:UC8_RS00980
uniprot id: A0A5B9QWD2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS22680
gene id: 980254:UC8_RS22680
uniprot id: A0A5B9QU11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Membrane

980254:UC8 RS18490
gene id: 980254:UC8_RS18490
uniprot id: A0A5B9QUR6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS25090
gene id: 980254:UC8_RS25090
uniprot id: A0A5B9QYE2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS25685
gene id: 980254:UC8_RS25685
uniprot id: A0A5B9R8K7
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

980254:UC8 RS25505
gene id: 980254:UC8_RS25505
uniprot id: A0A5B9R070
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS29160
gene id: 980254:UC8_RS29160
uniprot id: A0A5B9R0R6
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

980254:UC8 RS07520
gene id: 980254:UC8_RS07520
uniprot id: A0A5B9QPV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

980254:UC8 RS20890
gene id: 980254:UC8_RS20890
uniprot id: A0A5B9QWM2
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS08260
gene id: 980254:UC8_RS08260
uniprot id: A0A5B9QKU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS21780
gene id: 980254:UC8_RS21780
uniprot id: A0A5B9QTI6
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980254:UC8 RS13460
gene id: 980254:UC8_RS13460
uniprot id: A0A5B9QP20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

980254:UC8 RS01675
gene id: 980254:UC8_RS01675
uniprot id: A0A5B9QKV7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

980254:UC8 RS17835
gene id: 980254:UC8_RS17835
uniprot id: A0A5B9QRC5
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS16160
gene id: 980254:UC8_RS16160
uniprot id: A0A5B9QQJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

980254:UC8 RS18655
gene id: 980254:UC8_RS18655
uniprot id: A0A5B9QUV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

980254:UC8 RS03180
gene id: 980254:UC8_RS03180
uniprot id: A0A5B9QIH8
names: Function
names: Similarity
messages: Belongs to the PduL family.
messages: Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate.

980254:UC8 RS04150
gene id: 980254:UC8_RS04150
uniprot id: A0A5B9QIN8
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

980254:UC8 RS23245
gene id: 980254:UC8_RS23245
uniprot id: A0A5B9R7I6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

980254:UC8 RS18875
gene id: 980254:UC8_RS18875
uniprot id: A0A5B9QWM5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS23060
gene id: 980254:UC8_RS23060
uniprot id: A0A5B9QX91
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

980254:UC8 RS05830
gene id: 980254:UC8_RS05830
uniprot id: A0A5B9QZ06
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS10865
gene id: 980254:UC8_RS10865
uniprot id: A0A5B9QM76
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

980254:UC8 RS28255
gene id: 980254:UC8_RS28255
uniprot id: A0A5B9QXC8
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS01575
gene id: 980254:UC8_RS01575
uniprot id: A0A5B9QKU2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

980254:UC8 RS15240
gene id: 980254:UC8_RS15240
uniprot id: A0A5B9QT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

980254:UC8 RS11025
gene id: 980254:UC8_RS11025
uniprot id: A0A5B9QQS0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

980254:UC8 RS14160
gene id: 980254:UC8_RS14160
uniprot id: A0A5B9QPH1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS09700
gene id: 980254:UC8_RS09700
uniprot id: A0A5B9R1A9
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

980254:UC8 RS03195
gene id: 980254:UC8_RS03195
uniprot id: A0A5B9QHU6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mg(2+). Can also accept Mn(2+).

980254:UC8 RS23725
gene id: 980254:UC8_RS23725
uniprot id: A0A5B9R869
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS02430
gene id: 980254:UC8_RS02430
uniprot id: A0A5B9QI50
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

980254:UC8 RS15950
gene id: 980254:UC8_RS15950
uniprot id: A0A5B9R471
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

980254:UC8 RS10925
gene id: 980254:UC8_RS10925
uniprot id: A0A5B9QQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

980254:UC8 RS25620
gene id: 980254:UC8_RS25620
uniprot id: A0A5B9QVS4
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit.

980254:UC8 RS05055
gene id: 980254:UC8_RS05055
uniprot id: A0A5B9QJI1
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS23050
gene id: 980254:UC8_RS23050
uniprot id: A0A5B9R7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

980254:UC8 RS12285
gene id: 980254:UC8_RS12285
uniprot id: A0A5B9QTU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

980254:UC8 RS20665
gene id: 980254:UC8_RS20665
uniprot id: A0A5B9QYD7
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS07440
gene id: 980254:UC8_RS07440
uniprot id: A0A5B9QPD4
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS03580
gene id: 980254:UC8_RS03580
uniprot id: A0A5B9QIP9
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS24405
gene id: 980254:UC8_RS24405
uniprot id: A0A5B9QYH0
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

980254:UC8 RS24510
gene id: 980254:UC8_RS24510
uniprot id: A0A5B9QY29
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS04620
gene id: 980254:UC8_RS04620
uniprot id: A0A5B9QYG9
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS16430
gene id: 980254:UC8_RS16430
uniprot id: A0A5B9QTR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980254:UC8 RS24670
gene id: 980254:UC8_RS24670
uniprot id: A0A5B9QZU0
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS11000
gene id: 980254:UC8_RS11000
uniprot id: A0A5B9QMS4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

980254:UC8 RS08055
gene id: 980254:UC8_RS08055
uniprot id: A0A5B9QKM0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the spermidine/spermine synthase family.
messages: Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
messages: Cell membrane
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS09530
gene id: 980254:UC8_RS09530
uniprot id: A0A5B9QRB4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

980254:UC8 RS24325
gene id: 980254:UC8_RS24325
uniprot id: A0A5B9QV28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

980254:UC8 RS00010
gene id: 980254:UC8_RS00010
uniprot id: A0A5B9QKD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

980254:UC8 RS10530
gene id: 980254:UC8_RS10530
uniprot id: A0A5B9QQG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

980254:UC8 RS10010
gene id: 980254:UC8_RS10010
uniprot id: A0A5B9QSM7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS20515
gene id: 980254:UC8_RS20515
uniprot id: A0A5B9QSR7
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS19435
gene id: 980254:UC8_RS19435
uniprot id: A0A5B9QS71
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS21900
gene id: 980254:UC8_RS21900
uniprot id: A0A5B9QX59
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

980254:UC8 RS02615
gene id: 980254:UC8_RS02615
uniprot id: A0A5B9QLB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980254:UC8 RS02565
gene id: 980254:UC8_RS02565
uniprot id: A0A5B9QLB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane

980254:UC8 RS24485
gene id: 980254:UC8_RS24485
uniprot id: A0A5B9QV43
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family. N-terminal subunit subfamily.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.

980254:UC8 RS07685
gene id: 980254:UC8_RS07685
uniprot id: A0A5B9QNV7
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

980254:UC8 RS19185
gene id: 980254:UC8_RS19185
uniprot id: A0A5B9QS24
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

980254:UC8 RS04320
gene id: 980254:UC8_RS04320
uniprot id: A0A5B9QJ46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

980254:UC8 RS05315
gene id: 980254:UC8_RS05315
uniprot id: A0A5B9QQ10
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L-fucose isomerase family.
messages: Converts the aldose L-fucose into the corresponding ketose L-fuculose.
messages: Cytoplasm

980254:UC8 RS23770
gene id: 980254:UC8_RS23770
uniprot id: A0A5B9QXN6
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

980254:UC8 RS16705
gene id: 980254:UC8_RS16705
uniprot id: A0A5B9QQH8
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

980254:UC8 RS27705
gene id: 980254:UC8_RS27705
uniprot id: A0A5B9QWY7
names: Cofactor
messages: Binds 1 zinc ion per subunit.

980254:UC8 RS20365
gene id: 980254:UC8_RS20365
uniprot id: A0A5B9QW15
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980254:UC8 RS29125
gene id: 980254:UC8_RS29125
uniprot id: A0A5B9R0E2
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

980254:UC8 RS23525
gene id: 980254:UC8_RS23525
uniprot id: A0A5B9R7N1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS05435
gene id: 980254:UC8_RS05435
uniprot id: A0A5B9QYS7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

980254:UC8 RS02495
gene id: 980254:UC8_RS02495
uniprot id: A0A5B9QHF3
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.

980254:UC8 RS24635
gene id: 980254:UC8_RS24635
uniprot id: A0A5B9QV84
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

980254:UC8 RS18240
gene id: 980254:UC8_RS18240
uniprot id: A0A5B9QUL8
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

980254:UC8 RS25370
gene id: 980254:UC8_RS25370
uniprot id: A0A5B9QVM0
names: Similarity
messages: Belongs to the OprB family.

980254:UC8 RS18575
gene id: 980254:UC8_RS18575
uniprot id: A0A5B9QX77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Cell membrane
messages: Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.

980254:UC8 RS14100
gene id: 980254:UC8_RS14100
uniprot id: A0A5B9R3D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS18665
gene id: 980254:UC8_RS18665
uniprot id: A0A5B9QRX3
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

980254:UC8 RS21080
gene id: 980254:UC8_RS21080
uniprot id: A0A5B9QWF2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

980254:UC8 RS18175
gene id: 980254:UC8_RS18175
uniprot id: A0A5B9QW85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

980254:UC8 RS29900
gene id: 980254:UC8_RS29900
uniprot id: A0A5B9QYV1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS00310
gene id: 980254:UC8_RS00310
uniprot id: A0A5B9QVR7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS10900
gene id: 980254:UC8_RS10900
uniprot id: A0A5B9QMQ4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

980254:UC8 RS27785
gene id: 980254:UC8_RS27785
uniprot id: A0A5B9R038
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

980254:UC8 RS02380
gene id: 980254:UC8_RS02380
uniprot id: A0A5B9QX49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

980254:UC8 RS27210
gene id: 980254:UC8_RS27210
uniprot id: A0A5B9QWN9
names: Similarity
messages: Belongs to the peptidase S8 family.

980254:UC8 RS24295
gene id: 980254:UC8_RS24295
uniprot id: A0A5B9QV11
names: Similarity
messages: Belongs to the DapA family.

980254:UC8 RS04225
gene id: 980254:UC8_RS04225
uniprot id: A0A5B9QN52
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

980254:UC8 RS07445
gene id: 980254:UC8_RS07445
uniprot id: A0A5B9QZU7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

980254:UC8 RS07770
gene id: 980254:UC8_RS07770
uniprot id: A0A5B9QNT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

980254:UC8 RS07110
gene id: 980254:UC8_RS07110
uniprot id: A0A5B9QNI6
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

980254:UC8 RS19440
gene id: 980254:UC8_RS19440
uniprot id: A0A5B9QVH2
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS27345
gene id: 980254:UC8_RS27345
uniprot id: A0A5B9QZI2
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS02945
gene id: 980254:UC8_RS02945
uniprot id: A0A5B9QNQ5
names: Similarity
messages: Belongs to the ABC transporter superfamily.

980254:UC8 RS21600
gene id: 980254:UC8_RS21600
uniprot id: A0A5B9R6U0
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

980254:UC8 RS03995
gene id: 980254:UC8_RS03995
uniprot id: A0A5B9QI95
names: Similarity
messages: Belongs to the thioredoxin family.

980254:UC8 RS22765
gene id: 980254:UC8_RS22765
uniprot id: A0A5B9QU79
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS19640
gene id: 980254:UC8_RS19640
uniprot id: A0A5B9QVY7
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

980254:UC8 RS13655
gene id: 980254:UC8_RS13655
uniprot id: A0A5B9QS18
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

980254:UC8 RS18675
gene id: 980254:UC8_RS18675
uniprot id: A0A5B9QX98
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

980254:UC8 RS07895
gene id: 980254:UC8_RS07895
uniprot id: A0A5B9QL34
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS12720
gene id: 980254:UC8_RS12720
uniprot id: A0A5B9QNH4
names: Similarity
messages: Belongs to the universal stress protein A family.

980254:UC8 RS05945
gene id: 980254:UC8_RS05945
uniprot id: A0A5B9QP35
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS21030
gene id: 980254:UC8_RS21030
uniprot id: A0A5B9QT79
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FGAMS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

980254:UC8 RS02870
gene id: 980254:UC8_RS02870
uniprot id: A0A5B9QXD8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS00995
gene id: 980254:UC8_RS00995
uniprot id: A0A5B9QL64
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

980254:UC8 RS12510
gene id: 980254:UC8_RS12510
uniprot id: A0A5B9QU06
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS17585
gene id: 980254:UC8_RS17585
uniprot id: A0A5B9QU96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980254:UC8 RS23145
gene id: 980254:UC8_RS23145
uniprot id: A0A5B9QXU9
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

980254:UC8 RS01135
gene id: 980254:UC8_RS01135
uniprot id: A0A5B9QWG1
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980254:UC8 RS25705
gene id: 980254:UC8_RS25705
uniprot id: A0A5B9R0B0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Membrane

980254:UC8 RS24235
gene id: 980254:UC8_RS24235
uniprot id: A0A5B9R0C4
names: Similarity
messages: Belongs to the Fur family.

980254:UC8 RS24425
gene id: 980254:UC8_RS24425
uniprot id: A0A5B9R0G0
names: Function
names: Similarity
messages: Belongs to the PstS family.
messages: Involved in the system for phosphate transport across the cytoplasmic membrane.

980254:UC8 RS22710
gene id: 980254:UC8_RS22710
uniprot id: A0A5B9R7U5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

980254:UC8 RS25125
gene id: 980254:UC8_RS25125
uniprot id: A0A5B9QYN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS13835
gene id: 980254:UC8_RS13835
uniprot id: A0A5B9QSA2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS17425
gene id: 980254:UC8_RS17425
uniprot id: A0A5B9QQW0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

980254:UC8 RS28345
gene id: 980254:UC8_RS28345
uniprot id: A0A5B9R2P2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS21500
gene id: 980254:UC8_RS21500
uniprot id: A0A5B9R6S7
names: Similarity
messages: Belongs to the thioesterase family.

980254:UC8 RS22460
gene id: 980254:UC8_RS22460
uniprot id: A0A5B9QXG4
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS09015
gene id: 980254:UC8_RS09015
uniprot id: A0A5B9QPK0
names: Similarity
messages: Belongs to the peptidase M24B family.

980254:UC8 RS14260
gene id: 980254:UC8_RS14260
uniprot id: A0A5B9QTZ1
names: Similarity
messages: Belongs to the UPF0065 (bug) family.

980254:UC8 RS16725
gene id: 980254:UC8_RS16725
uniprot id: A0A5B9R4H8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS14490
gene id: 980254:UC8_RS14490
uniprot id: A0A5B9R3K1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

980254:UC8 RS02890
gene id: 980254:UC8_RS02890
uniprot id: A0A5B9QID1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

980254:UC8 RS21010
gene id: 980254:UC8_RS21010
uniprot id: A0A5B9QT69
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

980254:UC8 RS13535
gene id: 980254:UC8_RS13535
uniprot id: A0A5B9QS49
names: Similarity
messages: Belongs to the glutamate synthase family.

980254:UC8 RS13490
gene id: 980254:UC8_RS13490
uniprot id: A0A5B9QSL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

980254:UC8 RS26160
gene id: 980254:UC8_RS26160
uniprot id: A0A5B9QW23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS09210
gene id: 980254:UC8_RS09210
uniprot id: A0A5B9QR36
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

980254:UC8 RS03410
gene id: 980254:UC8_RS03410
uniprot id: A0A5B9QXQ4
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

980254:UC8 RS27755
gene id: 980254:UC8_RS27755
uniprot id: A0A5B9QWZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

980254:UC8 RS03960
gene id: 980254:UC8_RS03960
uniprot id: A0A5B9QMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm
messages: Mitochondrion

980254:UC8 RS04605
gene id: 980254:UC8_RS04605
uniprot id: A0A5B9QMY0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS16790
gene id: 980254:UC8_RS16790
uniprot id: A0A5B9QQV0
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
messages: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS28540
gene id: 980254:UC8_RS28540
uniprot id: A0A5B9R1P8
names: Domain
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

980254:UC8 RS26105
gene id: 980254:UC8_RS26105
uniprot id: A0A5B9R921
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS26285
gene id: 980254:UC8_RS26285
uniprot id: A0A5B9QZ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

980254:UC8 RS27790
gene id: 980254:UC8_RS27790
uniprot id: A0A5B9R9C6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS12765
gene id: 980254:UC8_RS12765
uniprot id: A0A5B9QN97
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS07690
gene id: 980254:UC8_RS07690
uniprot id: A0A5B9QZZ9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

980254:UC8 RS20735
gene id: 980254:UC8_RS20735
uniprot id: A0A5B9QWJ0
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

980254:UC8 RS25650
gene id: 980254:UC8_RS25650
uniprot id: A0A5B9R8X3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

980254:UC8 RS28300
gene id: 980254:UC8_RS28300
uniprot id: A0A5B9R2N2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

980254:UC8 RS01650
gene id: 980254:UC8_RS01650
uniprot id: A0A5B9QH01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

980254:UC8 RS18400
gene id: 980254:UC8_RS18400
uniprot id: A0A5B9QV63
names: Similarity
messages: Belongs to the pirin family.

980254:UC8 RS28810
gene id: 980254:UC8_RS28810
uniprot id: A0A5B9R0N3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS02900
gene id: 980254:UC8_RS02900
uniprot id: A0A5B9QNP5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980254:UC8 RS18790
gene id: 980254:UC8_RS18790
uniprot id: A0A5B9QUX0
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for chromosome condensation and partitioning.

980254:UC8 RS22375
gene id: 980254:UC8_RS22375
uniprot id: A0A5B9R734
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

980254:UC8 RS26175
gene id: 980254:UC8_RS26175
uniprot id: A0A5B9QW75
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

980254:UC8 RS18805
gene id: 980254:UC8_RS18805
uniprot id: A0A5B9R5H8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

980254:UC8 RS14250
gene id: 980254:UC8_RS14250
uniprot id: A0A5B9R3G9
names: Similarity
messages: Belongs to the Fur family.

980254:UC8 RS10275
gene id: 980254:UC8_RS10275
uniprot id: A0A5B9QR19
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

980254:UC8 RS04460
gene id: 980254:UC8_RS04460
uniprot id: A0A5B9QYE8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

980254:UC8 RS24645
gene id: 980254:UC8_RS24645
uniprot id: A0A5B9QYM4
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

980254:UC8 RS24310
gene id: 980254:UC8_RS24310
uniprot id: A0A5B9R807
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

980254:UC8 RS22385
gene id: 980254:UC8_RS22385
uniprot id: A0A5B9R7N3
names: Similarity
messages: Belongs to the ABC transporter superfamily.

980254:UC8 RS12640
gene id: 980254:UC8_RS12640
uniprot id: A0A5B9QRH8
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS05855
gene id: 980254:UC8_RS05855
uniprot id: A0A5B9QQB9
names: Similarity
messages: Belongs to the bacterial solute-binding protein ModA family.

980254:UC8 RS13270
gene id: 980254:UC8_RS13270
uniprot id: A0A5B9QUF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

980254:UC8 RS11005
gene id: 980254:UC8_RS11005
uniprot id: A0A5B9QS91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

980254:UC8 RS19490
gene id: 980254:UC8_RS19490
uniprot id: A0A5B9QVU6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

980254:UC8 RS12820
gene id: 980254:UC8_RS12820
uniprot id: A0A5B9QNA6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS25095
gene id: 980254:UC8_RS25095
uniprot id: A0A5B9R8Q8
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

980254:UC8 RS20760
gene id: 980254:UC8_RS20760
uniprot id: A0A5B9QT19
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

980254:UC8 RS20420
gene id: 980254:UC8_RS20420
uniprot id: A0A5B9QWE2
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

980254:UC8 RS28775
gene id: 980254:UC8_RS28775
uniprot id: A0A5B9RA61
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS15400
gene id: 980254:UC8_RS15400
uniprot id: A0A5B9R3Y4
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

980254:UC8 RS07470
gene id: 980254:UC8_RS07470
uniprot id: A0A5B9QR65
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

980254:UC8 RS21980
gene id: 980254:UC8_RS21980
uniprot id: A0A5B9QYD5
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980254:UC8 RS09810
gene id: 980254:UC8_RS09810
uniprot id: A0A5B9QM24
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

980254:UC8 RS07495
gene id: 980254:UC8_RS07495
uniprot id: A0A5B9QPE4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

980254:UC8 RS25585
gene id: 980254:UC8_RS25585
uniprot id: A0A5B9R8J7
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

980254:UC8 RS16810
gene id: 980254:UC8_RS16810
uniprot id: A0A5B9QQT2
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS25660
gene id: 980254:UC8_RS25660
uniprot id: A0A5B9R0A2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

980254:UC8 RS17060
gene id: 980254:UC8_RS17060
uniprot id: A0A5B9QQP9
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

980254:UC8 RS09270
gene id: 980254:UC8_RS09270
uniprot id: A0A5B9QS83
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

980254:UC8 RS21575
gene id: 980254:UC8_RS21575
uniprot id: A0A5B9QYT8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS08780
gene id: 980254:UC8_RS08780
uniprot id: A0A5B9R0K5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

980254:UC8 RS04875
gene id: 980254:UC8_RS04875
uniprot id: A0A5B9QPS8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

980254:UC8 RS02240
gene id: 980254:UC8_RS02240
uniprot id: A0A5B9QLU1
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS19345
gene id: 980254:UC8_RS19345
uniprot id: A0A5B9QVR1
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

980254:UC8 RS01115
gene id: 980254:UC8_RS01115
uniprot id: A0A5B9QJX6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS18660
gene id: 980254:UC8_RS18660
uniprot id: A0A5B9R673
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PAPS reductase family. CysD subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: With CysN forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

980254:UC8 RS28870
gene id: 980254:UC8_RS28870
uniprot id: A0A5B9R0A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-3 family.
messages: Cytoplasm
messages: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
messages: Monomer.

980254:UC8 RS01600
gene id: 980254:UC8_RS01600
uniprot id: A0A5B9QGZ7
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

980254:UC8 RS23150
gene id: 980254:UC8_RS23150
uniprot id: A0A5B9R7H2
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

980254:UC8 RS13025
gene id: 980254:UC8_RS13025
uniprot id: A0A5B9QNN1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980254:UC8 RS19605
gene id: 980254:UC8_RS19605
uniprot id: A0A5B9R6K1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS07525
gene id: 980254:UC8_RS07525
uniprot id: A0A5B9QR76
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

980254:UC8 RS16390
gene id: 980254:UC8_RS16390
uniprot id: A0A5B9QW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980254:UC8 RS03685
gene id: 980254:UC8_RS03685
uniprot id: A0A5B9QMT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

980254:UC8 RS19180
gene id: 980254:UC8_RS19180
uniprot id: A0A5B9QRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

980254:UC8 RS20030
gene id: 980254:UC8_RS20030
uniprot id: A0A5B9QXC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980254:UC8 RS11080
gene id: 980254:UC8_RS11080
uniprot id: A0A5B9QQS8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the zinc-containing alcohol dehydrogenase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate.
messages: Cytoplasm
messages: Homotetramer.

980254:UC8 RS11085
gene id: 980254:UC8_RS11085
uniprot id: A0A5B9QRG0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.

980254:UC8 RS18420
gene id: 980254:UC8_RS18420
uniprot id: A0A5B9QRR2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS23880
gene id: 980254:UC8_RS23880
uniprot id: A0A5B9QUU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980254:UC8 RS08930
gene id: 980254:UC8_RS08930
uniprot id: A0A5B9QPJ6
names: Similarity
messages: Belongs to the SUI1 family.

980254:UC8 RS11320
gene id: 980254:UC8_RS11320
uniprot id: A0A5B9QQX0
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.

980254:UC8 RS28945
gene id: 980254:UC8_RS28945
uniprot id: A0A5B9R2Y6
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS06205
gene id: 980254:UC8_RS06205
uniprot id: A0A5B9QMK5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS02075
gene id: 980254:UC8_RS02075
uniprot id: A0A5B9QWY6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS22140
gene id: 980254:UC8_RS22140
uniprot id: A0A5B9QYG3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

980254:UC8 RS12745
gene id: 980254:UC8_RS12745
uniprot id: A0A5B9R2P4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS18160
gene id: 980254:UC8_RS18160
uniprot id: A0A5B9QUL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

980254:UC8 RS07345
gene id: 980254:UC8_RS07345
uniprot id: A0A5B9QPB6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Membrane

980254:UC8 RS05320
gene id: 980254:UC8_RS05320
uniprot id: A0A5B9QJ37
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

980254:UC8 RS23365
gene id: 980254:UC8_RS23365
uniprot id: A0A5B9QUG0
names: Similarity
messages: Belongs to the disproportionating enzyme family.

980254:UC8 RS19700
gene id: 980254:UC8_RS19700
uniprot id: A0A5B9QVH4
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

980254:UC8 RS26660
gene id: 980254:UC8_RS26660
uniprot id: A0A5B9R0S9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

980254:UC8 RS14840
gene id: 980254:UC8_RS14840
uniprot id: A0A5B9QSX7
names: Similarity
messages: Belongs to the peptidase C56 family.

980254:UC8 RS22275
gene id: 980254:UC8_RS22275
uniprot id: A0A5B9QWU2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS13540
gene id: 980254:UC8_RS13540
uniprot id: A0A5B9QSM5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

980254:UC8 RS25525
gene id: 980254:UC8_RS25525
uniprot id: A0A5B9QYU8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS07865
gene id: 980254:UC8_RS07865
uniprot id: A0A5B9QKL9
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS07480
gene id: 980254:UC8_RS07480
uniprot id: A0A5B9QKE3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

980254:UC8 RS02145
gene id: 980254:UC8_RS02145
uniprot id: A0A5B9QN91
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS27995
gene id: 980254:UC8_RS27995
uniprot id: A0A5B9R1F6
names: Similarity
messages: Belongs to the cytochrome c-552 family.

980254:UC8 RS27830
gene id: 980254:UC8_RS27830
uniprot id: A0A5B9R001
names: Similarity
messages: Belongs to the SCO1/2 family.

980254:UC8 RS14990
gene id: 980254:UC8_RS14990
uniprot id: A0A5B9QSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980254:UC8 RS03630
gene id: 980254:UC8_RS03630
uniprot id: A0A5B9QIQ6
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

980254:UC8 RS21960
gene id: 980254:UC8_RS21960
uniprot id: A0A5B9QWN7
names: Similarity
messages: Belongs to the GSP E family.

980254:UC8 RS06910
gene id: 980254:UC8_RS06910
uniprot id: A0A5B9QZK5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS08270
gene id: 980254:UC8_RS08270
uniprot id: A0A5B9QP23
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS24965
gene id: 980254:UC8_RS24965
uniprot id: A0A5B9R0S3
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

980254:UC8 RS09510
gene id: 980254:UC8_RS09510
uniprot id: A0A5B9R174
names: Similarity
messages: Belongs to the HisA/HisF family.

980254:UC8 RS00595
gene id: 980254:UC8_RS00595
uniprot id: A0A5B9QKA6
names: Similarity
messages: Belongs to the DapA family.

980254:UC8 RS27695
gene id: 980254:UC8_RS27695
uniprot id: A0A5B9QZN8
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

980254:UC8 RS24265
gene id: 980254:UC8_RS24265
uniprot id: A0A5B9QXY1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS27315
gene id: 980254:UC8_RS27315
uniprot id: A0A5B9R228
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

980254:UC8 RS08785
gene id: 980254:UC8_RS08785
uniprot id: A0A5B9QLH8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

980254:UC8 RS26930
gene id: 980254:UC8_RS26930
uniprot id: A0A5B9QWL2
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

980254:UC8 RS07515
gene id: 980254:UC8_RS07515
uniprot id: A0A5B9QKW5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

980254:UC8 RS21445
gene id: 980254:UC8_RS21445
uniprot id: A0A5B9QWX6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

980254:UC8 RS13180
gene id: 980254:UC8_RS13180
uniprot id: A0A5B9QRX4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

980254:UC8 RS09800
gene id: 980254:UC8_RS09800
uniprot id: A0A5B9QQ15
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS30155
gene id: 980254:UC8_RS30155
uniprot id: A0A5B9QWH1
names: Similarity
messages: Belongs to the DtxR/MntR family.

980254:UC8 RS07375
gene id: 980254:UC8_RS07375
uniprot id: A0A5B9QR51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

980254:UC8 RS25930
gene id: 980254:UC8_RS25930
uniprot id: A0A5B9QVZ0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS06855
gene id: 980254:UC8_RS06855
uniprot id: A0A5B9QPH5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

980254:UC8 RS10460
gene id: 980254:UC8_RS10460
uniprot id: A0A5B9QRZ4
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

980254:UC8 RS21265
gene id: 980254:UC8_RS21265
uniprot id: A0A5B9R752
names: Similarity
messages: Belongs to the MEMO1 family.

980254:UC8 RS22035
gene id: 980254:UC8_RS22035
uniprot id: A0A5B9QTN8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

980254:UC8 RS08970
gene id: 980254:UC8_RS08970
uniprot id: A0A5B9QQA4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS28120
gene id: 980254:UC8_RS28120
uniprot id: A0A5B9R0A3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial diacylglycerol kinase family.
messages: Membrane

980254:UC8 RS09315
gene id: 980254:UC8_RS09315
uniprot id: A0A5B9QR60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

980254:UC8 RS22160
gene id: 980254:UC8_RS22160
uniprot id: A0A5B9QX28
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

980254:UC8 RS00895
gene id: 980254:UC8_RS00895
uniprot id: A0A5B9QL49
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS19670
gene id: 980254:UC8_RS19670
uniprot id: A0A5B9QXX7
names: Similarity
messages: Belongs to the peptidase S8 family.

980254:UC8 RS17820
gene id: 980254:UC8_RS17820
uniprot id: A0A5B9QW20
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

980254:UC8 RS05535
gene id: 980254:UC8_RS05535
uniprot id: A0A5B9QYV3
names: Subcellular Location Annotation
messages: Cytoplasm

980254:UC8 RS11175
gene id: 980254:UC8_RS11175
uniprot id: A0A5B9QMR3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

980254:UC8 RS21655
gene id: 980254:UC8_RS21655
uniprot id: A0A5B9QWH9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

980254:UC8 RS12605
gene id: 980254:UC8_RS12605
uniprot id: A0A5B9QU27
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980254:UC8 RS10320
gene id: 980254:UC8_RS10320
uniprot id: A0A5B9QM86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

980254:UC8 RS25865
gene id: 980254:UC8_RS25865
uniprot id: A0A5B9QVW8
names: Similarity
messages: Belongs to the intimin/invasin family.

980254:UC8 RS15715
gene id: 980254:UC8_RS15715
uniprot id: A0A5B9QQB2
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS23555
gene id: 980254:UC8_RS23555
uniprot id: A0A5B9QUK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.

980254:UC8 RS25310
gene id: 980254:UC8_RS25310
uniprot id: A0A5B9R039
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

980254:UC8 RS18190
gene id: 980254:UC8_RS18190
uniprot id: A0A5B9QUK9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS25740
gene id: 980254:UC8_RS25740
uniprot id: A0A5B9QYQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Cell inner membrane
messages: Membrane

980254:UC8 RS27450
gene id: 980254:UC8_RS27450
uniprot id: A0A5B9QZJ8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

980254:UC8 RS25215
gene id: 980254:UC8_RS25215
uniprot id: A0A5B9R0W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

980254:UC8 RS23565
gene id: 980254:UC8_RS23565
uniprot id: A0A5B9QXX1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

980254:UC8 RS20925
gene id: 980254:UC8_RS20925
uniprot id: A0A5B9QSV1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS06090
gene id: 980254:UC8_RS06090
uniprot id: A0A5B9QP62
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980254:UC8 RS04195
gene id: 980254:UC8_RS04195
uniprot id: A0A5B9QLJ8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980254:UC8 RS22600
gene id: 980254:UC8_RS22600
uniprot id: A0A5B9QXJ3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS16925
gene id: 980254:UC8_RS16925
uniprot id: A0A5B9QUF8
names: Subcellular Location Annotation
messages: Cytoplasm

980254:UC8 RS16750
gene id: 980254:UC8_RS16750
uniprot id: A0A5B9QW88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

980254:UC8 RS24925
gene id: 980254:UC8_RS24925
uniprot id: A0A5B9QVD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

980254:UC8 RS14165
gene id: 980254:UC8_RS14165
uniprot id: A0A5B9QTX6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS22095
gene id: 980254:UC8_RS22095
uniprot id: A0A5B9QZ34
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm

980254:UC8 RS12150
gene id: 980254:UC8_RS12150
uniprot id: A0A5B9QRZ7
names: Function
names: Similarity
messages: Belongs to the transposase mutator family.
messages: Required for the transposition of the insertion element.

980254:UC8 RS14585
gene id: 980254:UC8_RS14585
uniprot id: A0A5B9QT77
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

980254:UC8 RS21055
gene id: 980254:UC8_RS21055
uniprot id: A0A5B9R736
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

980254:UC8 RS14740
gene id: 980254:UC8_RS14740
uniprot id: A0A5B9R3P2
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

980254:UC8 RS03245
gene id: 980254:UC8_RS03245
uniprot id: A0A5B9QHV4
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

980254:UC8 RS10395
gene id: 980254:UC8_RS10395
uniprot id: A0A5B9QQD1
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS20825
gene id: 980254:UC8_RS20825
uniprot id: A0A5B9QST1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

980254:UC8 RS04160
gene id: 980254:UC8_RS04160
uniprot id: A0A5B9QY56
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS07870
gene id: 980254:UC8_RS07870
uniprot id: A0A5B9QNU5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS08625
gene id: 980254:UC8_RS08625
uniprot id: A0A5B9R0I1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS01030
gene id: 980254:UC8_RS01030
uniprot id: A0A5B9QKI6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980254:UC8 RS20375
gene id: 980254:UC8_RS20375
uniprot id: A0A5B9R6D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TsaE family.
messages: Cytoplasm

980254:UC8 RS02485
gene id: 980254:UC8_RS02485
uniprot id: A0A5B9QM42
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

980254:UC8 RS18155
gene id: 980254:UC8_RS18155
uniprot id: A0A5B9R579
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

980254:UC8 RS17025
gene id: 980254:UC8_RS17025
uniprot id: A0A5B9QUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

980254:UC8 RS28865
gene id: 980254:UC8_RS28865
uniprot id: A0A5B9R9U2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

980254:UC8 RS00780
gene id: 980254:UC8_RS00780
uniprot id: A0A5B9QKE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

980254:UC8 RS27990
gene id: 980254:UC8_RS27990
uniprot id: A0A5B9QX39
names: Similarity
messages: Belongs to the globin family.

980254:UC8 RS25130
gene id: 980254:UC8_RS25130
uniprot id: A0A5B9QYX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980254:UC8 RS00330
gene id: 980254:UC8_RS00330
uniprot id: A0A5B9QKP5
names: Similarity
messages: Belongs to the LOR family.

980254:UC8 RS07830
gene id: 980254:UC8_RS07830
uniprot id: A0A5B9R031
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

980254:UC8 RS07205
gene id: 980254:UC8_RS07205
uniprot id: A0A5B9QZQ6
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

980254:UC8 RS27375
gene id: 980254:UC8_RS27375
uniprot id: A0A5B9QWS6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS09955
gene id: 980254:UC8_RS09955
uniprot id: A0A5B9QRR6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980254:UC8 RS14880
gene id: 980254:UC8_RS14880
uniprot id: A0A5B9QSU7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS02300
gene id: 980254:UC8_RS02300
uniprot id: A0A5B9QHB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

980254:UC8 RS04985
gene id: 980254:UC8_RS04985
uniprot id: A0A5B9QYJ9
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS17800
gene id: 980254:UC8_RS17800
uniprot id: A0A5B9R4Z8
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.
messages: There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.

980254:UC8 RS01170
gene id: 980254:UC8_RS01170
uniprot id: A0A5B9QL51
names: Similarity
messages: Belongs to the peptidase C56 family.

980254:UC8 RS24140
gene id: 980254:UC8_RS24140
uniprot id: A0A5B9QUW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

980254:UC8 RS25665
gene id: 980254:UC8_RS25665
uniprot id: A0A5B9R169
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell membrane

980254:UC8 RS26080
gene id: 980254:UC8_RS26080
uniprot id: A0A5B9QW10
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

980254:UC8 RS15885
gene id: 980254:UC8_RS15885
uniprot id: A0A5B9QQ26
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

980254:UC8 RS11065
gene id: 980254:UC8_RS11065
uniprot id: A0A5B9QT52
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS19990
gene id: 980254:UC8_RS19990
uniprot id: A0A5B9QSB9
names: Similarity
messages: Belongs to the peptidase S51 family.

980254:UC8 RS17350
gene id: 980254:UC8_RS17350
uniprot id: A0A5B9QU67
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS00300
gene id: 980254:UC8_RS00300
uniprot id: A0A5B9QJG7
names: Similarity
messages: Belongs to the UPF0045 family.

980254:UC8 RS20045
gene id: 980254:UC8_RS20045
uniprot id: A0A5B9QSI3
names: Similarity
messages: Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.

980254:UC8 RS12210
gene id: 980254:UC8_RS12210
uniprot id: A0A5B9R2J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

980254:UC8 RS08855
gene id: 980254:UC8_RS08855
uniprot id: A0A5B9QLB7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

980254:UC8 RS25880
gene id: 980254:UC8_RS25880
uniprot id: A0A5B9QVY0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS12200
gene id: 980254:UC8_RS12200
uniprot id: A0A5B9QRE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS02810
gene id: 980254:UC8_RS02810
uniprot id: A0A5B9QKV2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

980254:UC8 RS08220
gene id: 980254:UC8_RS08220
uniprot id: A0A5B9QPU0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

980254:UC8 RS26455
gene id: 980254:UC8_RS26455
uniprot id: A0A5B9R968
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS19690
gene id: 980254:UC8_RS19690
uniprot id: A0A5B9QVZ5
names: Function
names: Similarity
messages: Belongs to the MqnA/MqnD family. MqnA subfamily.
messages: Catalyzes the dehydration of chorismate into 3-[(1-carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).

980254:UC8 RS07370
gene id: 980254:UC8_RS07370
uniprot id: A0A5B9QPS5
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

980254:UC8 RS02955
gene id: 980254:UC8_RS02955
uniprot id: A0A5B9QHW2
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS25120
gene id: 980254:UC8_RS25120
uniprot id: A0A5B9QVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980254:UC8 RS23590
gene id: 980254:UC8_RS23590
uniprot id: A0A5B9QUP5
names: Subcellular Location Annotation
messages: Cytoplasm

980254:UC8 RS23595
gene id: 980254:UC8_RS23595
uniprot id: A0A5B9QZ86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS21340
gene id: 980254:UC8_RS21340
uniprot id: A0A5B9QTD9
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

980254:UC8 RS10250
gene id: 980254:UC8_RS10250
uniprot id: A0A5B9QRW6
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

980254:UC8 RS18840
gene id: 980254:UC8_RS18840
uniprot id: A0A5B9QRW3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS14615
gene id: 980254:UC8_RS14615
uniprot id: A0A5B9QV50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS23390
gene id: 980254:UC8_RS23390
uniprot id: A0A5B9QXF7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980254:UC8 RS06815
gene id: 980254:UC8_RS06815
uniprot id: A0A5B9QJW7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS03535
gene id: 980254:UC8_RS03535
uniprot id: A0A5B9QMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980254:UC8 RS07755
gene id: 980254:UC8_RS07755
uniprot id: A0A5B9QRB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

980254:UC8 RS11385
gene id: 980254:UC8_RS11385
uniprot id: A0A5B9QQV4
names: Similarity
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.

980254:UC8 RS24430
gene id: 980254:UC8_RS24430
uniprot id: A0A5B9QV33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

980254:UC8 RS05730
gene id: 980254:UC8_RS05730
uniprot id: A0A5B9QNH9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

980254:UC8 RS02440
gene id: 980254:UC8_RS02440
uniprot id: A0A5B9QNF8
names: Similarity
messages: Belongs to the ycf81 family.

980254:UC8 RS04585
gene id: 980254:UC8_RS04585
uniprot id: A0A5B9QPN1
names: Similarity
messages: Belongs to the NodU/CmcH family.

980254:UC8 RS10565
gene id: 980254:UC8_RS10565
uniprot id: A0A5B9QSW4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

980254:UC8 RS03575
gene id: 980254:UC8_RS03575
uniprot id: A0A5B9QXU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980254:UC8 RS09230
gene id: 980254:UC8_RS09230
uniprot id: A0A5B9QPP2
names: Similarity
messages: Belongs to the group II decarboxylase family.

980254:UC8 RS12910
gene id: 980254:UC8_RS12910
uniprot id: A0A5B9QT65
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

980254:UC8 RS15215
gene id: 980254:UC8_RS15215
uniprot id: A0A5B9QQ14
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

980254:UC8 RS04610
gene id: 980254:UC8_RS04610
uniprot id: A0A5B9QYE0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS23460
gene id: 980254:UC8_RS23460
uniprot id: A0A5B9QUI1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS08210
gene id: 980254:UC8_RS08210
uniprot id: A0A5B9QKT8
names: Similarity
messages: Belongs to the MoaD family.

980254:UC8 RS28570
gene id: 980254:UC8_RS28570
uniprot id: A0A5B9R9N7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

980254:UC8 RS12630
gene id: 980254:UC8_RS12630
uniprot id: A0A5B9QS65
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

980254:UC8 RS24545
gene id: 980254:UC8_RS24545
uniprot id: A0A5B9QYE6
names: Similarity
messages: Belongs to the P(II) protein family.

980254:UC8 RS16845
gene id: 980254:UC8_RS16845
uniprot id: A0A5B9QVI1
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

980254:UC8 RS01905
gene id: 980254:UC8_RS01905
uniprot id: A0A5B9QH44
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

980254:UC8 RS15990
gene id: 980254:UC8_RS15990
uniprot id: A0A5B9QTX9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980254:UC8 RS15895
gene id: 980254:UC8_RS15895
uniprot id: A0A5B9QTC8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

980254:UC8 RS07970
gene id: 980254:UC8_RS07970
uniprot id: A0A5B9QNW3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

980254:UC8 RS27565
gene id: 980254:UC8_RS27565
uniprot id: A0A5B9R171
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

980254:UC8 RS07260
gene id: 980254:UC8_RS07260
uniprot id: A0A5B9QZQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS08460
gene id: 980254:UC8_RS08460
uniprot id: A0A5B9QRP8
names: Similarity
messages: Belongs to the creatininase superfamily.

980254:UC8 RS25180
gene id: 980254:UC8_RS25180
uniprot id: A0A5B9QYP6
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.

980254:UC8 RS04860
gene id: 980254:UC8_RS04860
uniprot id: A0A5B9QYL1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tRNA(Ile)-lysidine synthase family.
messages: Cytoplasm
messages: Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
messages: The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.

980254:UC8 RS16680
gene id: 980254:UC8_RS16680
uniprot id: A0A5B9QTW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS16005
gene id: 980254:UC8_RS16005
uniprot id: A0A5B9R4R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980254:UC8 RS21885
gene id: 980254:UC8_RS21885
uniprot id: A0A5B9QTK7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

980254:UC8 RS03190
gene id: 980254:UC8_RS03190
uniprot id: A0A5B9QNV4
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

980254:UC8 RS20995
gene id: 980254:UC8_RS20995
uniprot id: A0A5B9R6L0
names: Similarity
messages: Belongs to the SurE nucleotidase family.

980254:UC8 RS17480
gene id: 980254:UC8_RS17480
uniprot id: A0A5B9QQW9
names: Subcellular Location Annotation
messages: Periplasm

980254:UC8 RS11760
gene id: 980254:UC8_RS11760
uniprot id: A0A5B9QTJ2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS05775
gene id: 980254:UC8_RS05775
uniprot id: A0A5B9QMD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

980254:UC8 RS19190
gene id: 980254:UC8_RS19190
uniprot id: A0A5B9QV47
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS06410
gene id: 980254:UC8_RS06410
uniprot id: A0A5B9QNW4
names: Similarity
messages: Belongs to the KptA/TPT1 family.

980254:UC8 RS09040
gene id: 980254:UC8_RS09040
uniprot id: A0A5B9QLM8
names: Similarity
messages: Belongs to the FGGY kinase family.

980254:UC8 RS03490
gene id: 980254:UC8_RS03490
uniprot id: A0A5B9QP16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyribonucleotide nucleotidyltransferase family.
messages: Cytoplasm
messages: Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.

980254:UC8 RS27520
gene id: 980254:UC8_RS27520
uniprot id: A0A5B9R2B3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

980254:UC8 RS29295
gene id: 980254:UC8_RS29295
uniprot id: A0A5B9QN51
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

980254:UC8 RS15995
gene id: 980254:UC8_RS15995
uniprot id: A0A5B9R478
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980254:UC8 RS03185
gene id: 980254:UC8_RS03185
uniprot id: A0A5B9QMH8
names: Similarity
messages: Belongs to the bacterial microcompartments protein family.

980254:UC8 RS28150
gene id: 980254:UC8_RS28150
uniprot id: A0A5B9R2K9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS01455
gene id: 980254:UC8_RS01455
uniprot id: A0A5B9QH19
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

980254:UC8 RS21940
gene id: 980254:UC8_RS21940
uniprot id: A0A5B9QTP9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

980254:UC8 RS13450
gene id: 980254:UC8_RS13450
uniprot id: A0A5B9QRY0
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS07295
gene id: 980254:UC8_RS07295
uniprot id: A0A5B9QPA6
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

980254:UC8 RS25515
gene id: 980254:UC8_RS25515
uniprot id: A0A5B9QVQ1
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS25985
gene id: 980254:UC8_RS25985
uniprot id: A0A5B9QVZ3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

980254:UC8 RS27595
gene id: 980254:UC8_RS27595
uniprot id: A0A5B9R9A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

980254:UC8 RS04760
gene id: 980254:UC8_RS04760
uniprot id: A0A5B9QMD6
names: Similarity
messages: Belongs to the UPF0047 family.

980254:UC8 RS16255
gene id: 980254:UC8_RS16255
uniprot id: A0A5B9QU32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

980254:UC8 RS26575
gene id: 980254:UC8_RS26575
uniprot id: A0A5B9QWB4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

980254:UC8 RS07355
gene id: 980254:UC8_RS07355
uniprot id: A0A5B9QNP0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

980254:UC8 RS14245
gene id: 980254:UC8_RS14245
uniprot id: A0A5B9QSK2
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

980254:UC8 RS16930
gene id: 980254:UC8_RS16930
uniprot id: A0A5B9R4K7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

980254:UC8 RS23305
gene id: 980254:UC8_RS23305
uniprot id: A0A5B9QZ37
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

980254:UC8 RS20985
gene id: 980254:UC8_RS20985
uniprot id: A0A5B9QWC4
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980254:UC8 RS20430
gene id: 980254:UC8_RS20430
uniprot id: A0A5B9QVW0
names: Similarity
messages: Belongs to the peptidase M16 family.

980254:UC8 RS14500
gene id: 980254:UC8_RS14500
uniprot id: A0A5B9R3M0
names: Similarity
messages: Belongs to the YjdM family.

980254:UC8 RS26460
gene id: 980254:UC8_RS26460
uniprot id: A0A5B9QW98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

980254:UC8 RS03585
gene id: 980254:UC8_RS03585
uniprot id: A0A5B9QMR5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS03290
gene id: 980254:UC8_RS03290
uniprot id: A0A5B9QNX3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

980254:UC8 RS01830
gene id: 980254:UC8_RS01830
uniprot id: A0A5B9QWU3
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS19505
gene id: 980254:UC8_RS19505
uniprot id: A0A5B9R6I9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

980254:UC8 RS26650
gene id: 980254:UC8_RS26650
uniprot id: A0A5B9R998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

980254:UC8 RS08715
gene id: 980254:UC8_RS08715
uniprot id: A0A5B9QPC3
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS25775
gene id: 980254:UC8_RS25775
uniprot id: A0A5B9QYZ6
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS22645
gene id: 980254:UC8_RS22645
uniprot id: A0A5B9QXC9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

980254:UC8 RS07350
gene id: 980254:UC8_RS07350
uniprot id: A0A5B9QZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

980254:UC8 RS04855
gene id: 980254:UC8_RS04855
uniprot id: A0A5B9QME8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

980254:UC8 RS14645
gene id: 980254:UC8_RS14645
uniprot id: A0A5B9QSU4
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

980254:UC8 RS06400
gene id: 980254:UC8_RS06400
uniprot id: A0A5B9QJW0
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

980254:UC8 RS25830
gene id: 980254:UC8_RS25830
uniprot id: A0A5B9QZ10
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS15835
gene id: 980254:UC8_RS15835
uniprot id: A0A5B9QQ16
names: Subcellular Location Annotation
messages: Cytoplasm

980254:UC8 RS08400
gene id: 980254:UC8_RS08400
uniprot id: A0A5B9QLB2
names: Similarity
messages: Belongs to the DNA glycosylase MPG family.

980254:UC8 RS24685
gene id: 980254:UC8_RS24685
uniprot id: A0A5B9QV95
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

980254:UC8 RS07880
gene id: 980254:UC8_RS07880
uniprot id: A0A5B9R037
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980254:UC8 RS24495
gene id: 980254:UC8_RS24495
uniprot id: A0A5B9QYD8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

980254:UC8 RS29130
gene id: 980254:UC8_RS29130
uniprot id: A0A5B9RAC1
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

980254:UC8 RS01335
gene id: 980254:UC8_RS01335
uniprot id: A0A5B9QWJ3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

980254:UC8 RS27655
gene id: 980254:UC8_RS27655
uniprot id: A0A5B9QWX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

980254:UC8 RS14405
gene id: 980254:UC8_RS14405
uniprot id: A0A5B9QPM0
names: Similarity
messages: Belongs to the YciI family.

980254:UC8 RS11610
gene id: 980254:UC8_RS11610
uniprot id: A0A5B9QTF7
names: Similarity
messages: Belongs to the ParB family.

980254:UC8 RS15610
gene id: 980254:UC8_RS15610
uniprot id: A0A5B9R4K3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

980254:UC8 RS11750
gene id: 980254:UC8_RS11750
uniprot id: A0A5B9QN61
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

980254:UC8 RS02235
gene id: 980254:UC8_RS02235
uniprot id: A0A5B9QI16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980254:UC8 RS03380
gene id: 980254:UC8_RS03380
uniprot id: A0A5B9QIL5
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

980254:UC8 RS26445
gene id: 980254:UC8_RS26445
uniprot id: A0A5B9R8U9
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS24910
gene id: 980254:UC8_RS24910
uniprot id: A0A5B9R0R0
names: Similarity
messages: Belongs to the peptidase S1C family.

980254:UC8 RS12960
gene id: 980254:UC8_RS12960
uniprot id: A0A5B9QT75
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

980254:UC8 RS24360
gene id: 980254:UC8_RS24360
uniprot id: A0A5B9R816
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

980254:UC8 RS15525
gene id: 980254:UC8_RS15525
uniprot id: A0A5B9QUN7
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

980254:UC8 RS09265
gene id: 980254:UC8_RS09265
uniprot id: A0A5B9QR48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PTH family.
messages: Cytoplasm
messages: Monomer.
messages: The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

980254:UC8 RS24550
gene id: 980254:UC8_RS24550
uniprot id: A0A5B9QYK1
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

980254:UC8 RS06325
gene id: 980254:UC8_RS06325
uniprot id: A0A5B9QZA9
names: Similarity
messages: Belongs to the AHA1 family.

980254:UC8 RS11055
gene id: 980254:UC8_RS11055
uniprot id: A0A5B9QS98
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

980254:UC8 RS23985
gene id: 980254:UC8_RS23985
uniprot id: A0A5B9QZG1
names: Similarity
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.

980254:UC8 RS01940
gene id: 980254:UC8_RS01940
uniprot id: A0A5B9QHW4
names: Similarity
messages: Belongs to the glutamine synthetase family.

980254:UC8 RS24770
gene id: 980254:UC8_RS24770
uniprot id: A0A5B9QVA8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

980254:UC8 RS14505
gene id: 980254:UC8_RS14505
uniprot id: A0A5B9QPP0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980254:UC8 RS14600
gene id: 980254:UC8_RS14600
uniprot id: A0A5B9R3N5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

980254:UC8 RS16765
gene id: 980254:UC8_RS16765
uniprot id: A0A5B9QTV2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

980254:UC8 RS21350
gene id: 980254:UC8_RS21350
uniprot id: A0A5B9QWV2
names: Subcellular Location Annotation
messages: Cell inner membrane

980254:UC8 RS04565
gene id: 980254:UC8_RS04565
uniprot id: A0A5B9QMA4
names: Similarity
messages: Belongs to the asparagine synthetase family.

980254:UC8 RS05080
gene id: 980254:UC8_RS05080
uniprot id: A0A5B9QM18
names: Similarity
messages: Belongs to the UPF0162 family.

980254:UC8 RS28020
gene id: 980254:UC8_RS28020
uniprot id: A0A5B9R082
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

980254:UC8 RS10550
gene id: 980254:UC8_RS10550
uniprot id: A0A5B9R1G1
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS27230
gene id: 980254:UC8_RS27230
uniprot id: A0A5B9QWP0
names: Similarity
messages: Belongs to the UPF0235 family.

980254:UC8 RS05695
gene id: 980254:UC8_RS05695
uniprot id: A0A5B9QYZ8
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

980254:UC8 RS02045
gene id: 980254:UC8_RS02045
uniprot id: A0A5B9QLQ2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980254:UC8 RS01945
gene id: 980254:UC8_RS01945
uniprot id: A0A5B9QLN5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

980254:UC8 RS25425
gene id: 980254:UC8_RS25425
uniprot id: A0A5B9QVP0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980254:UC8 RS24215
gene id: 980254:UC8_RS24215
uniprot id: A0A5B9QXX4
names: Subcellular Location Annotation
messages: Membrane

980254:UC8 RS03235
gene id: 980254:UC8_RS03235
uniprot id: A0A5B9QMI9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

980254:UC8 RS03395
gene id: 980254:UC8_RS03395
uniprot id: A0A5B9QHY5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

980254:UC8 RS14215
gene id: 980254:UC8_RS14215
uniprot id: A0A5B9QTY3
names: Similarity
messages: Belongs to the bacterial secretin family.

980254:UC8 RS12250
gene id: 980254:UC8_RS12250
uniprot id: A0A5B9QRE7
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.