980251:MFFC18 RS11300
gene id: 980251:MFFC18_RS11300
uniprot id: A0A5B9PC88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

980251:MFFC18 RS11110
gene id: 980251:MFFC18_RS11110
uniprot id: A0A5B9P846
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

980251:MFFC18 RS09480
gene id: 980251:MFFC18_RS09480
uniprot id: A0A5B9P779
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20155
gene id: 980251:MFFC18_RS20155
uniprot id: A0A5B9PGF8
names: Similarity
messages: Belongs to the bacterial reverse transcriptase family.

980251:MFFC18 RS10505
gene id: 980251:MFFC18_RS10505
uniprot id: A0A5B9PBK0
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980251:MFFC18 RS03870
gene id: 980251:MFFC18_RS03870
uniprot id: A0A5B9P346
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

980251:MFFC18 RS23845
gene id: 980251:MFFC18_RS23845
uniprot id: A0A5B9PK93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.
messages: Cell membrane
messages: Membrane
messages: Probable transporter of a GTP-driven Fe(2+) uptake system.

980251:MFFC18 RS08345
gene id: 980251:MFFC18_RS08345
uniprot id: A0A5B9P6K3
names: Cofactor
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.

980251:MFFC18 RS12750
gene id: 980251:MFFC18_RS12750
uniprot id: A0A5B9PCF3
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS01225
gene id: 980251:MFFC18_RS01225
uniprot id: A0A5B9P1M3
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS06940
gene id: 980251:MFFC18_RS06940
uniprot id: A0A5B9P9H4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS13460
gene id: 980251:MFFC18_RS13460
uniprot id: A0A5B9P9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

980251:MFFC18 RS10160
gene id: 980251:MFFC18_RS10160
uniprot id: A0A5B9P6S1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS09545
gene id: 980251:MFFC18_RS09545
uniprot id: A0A5B9PH44
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

980251:MFFC18 RS16725
gene id: 980251:MFFC18_RS16725
uniprot id: A0A5B9PBI0
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

980251:MFFC18 RS19015
gene id: 980251:MFFC18_RS19015
uniprot id: A0A5B9PBN0
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS19185
gene id: 980251:MFFC18_RS19185
uniprot id: A0A5B9PHK1
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

980251:MFFC18 RS11695
gene id: 980251:MFFC18_RS11695
uniprot id: A0A5B9PCI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.

980251:MFFC18 RS08545
gene id: 980251:MFFC18_RS08545
uniprot id: A0A5B9PAH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

980251:MFFC18 RS21215
gene id: 980251:MFFC18_RS21215
uniprot id: A0A5B9PG30
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

980251:MFFC18 RS23600
gene id: 980251:MFFC18_RS23600
uniprot id: A0A5B9PS56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0718 family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS12520
gene id: 980251:MFFC18_RS12520
uniprot id: A0A5B9PCL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

980251:MFFC18 RS15385
gene id: 980251:MFFC18_RS15385
uniprot id: A0A5B9PDV7
names: Subcellular Location Annotation
messages: Periplasm

980251:MFFC18 RS15325
gene id: 980251:MFFC18_RS15325
uniprot id: A0A5B9PM49
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

980251:MFFC18 RS18520
gene id: 980251:MFFC18_RS18520
uniprot id: A0A5B9PHB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

980251:MFFC18 RS13895
gene id: 980251:MFFC18_RS13895
uniprot id: A0A5B9PDB0
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS20430
gene id: 980251:MFFC18_RS20430
uniprot id: A0A5B9PDK0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

980251:MFFC18 RS13820
gene id: 980251:MFFC18_RS13820
uniprot id: A0A5B9PD15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980251:MFFC18 RS23950
gene id: 980251:MFFC18_RS23950
uniprot id: A0A5B9PHQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS14635
gene id: 980251:MFFC18_RS14635
uniprot id: A0A5B9PKP2
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

980251:MFFC18 RS02030
gene id: 980251:MFFC18_RS02030
uniprot id: A0A5B9P2K5
names: Caution
names: Function
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.
messages: Catalyzes the specific phosphorylation of arginine residues in proteins.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS20735
gene id: 980251:MFFC18_RS20735
uniprot id: A0A5B9PPP0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS04645
gene id: 980251:MFFC18_RS04645
uniprot id: A0A5B9P7F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

980251:MFFC18 RS19610
gene id: 980251:MFFC18_RS19610
uniprot id: A0A5B9PHT0
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20685
gene id: 980251:MFFC18_RS20685
uniprot id: A0A5B9PIE1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

980251:MFFC18 RS17465
gene id: 980251:MFFC18_RS17465
uniprot id: A0A5B9PNG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

980251:MFFC18 RS11190
gene id: 980251:MFFC18_RS11190
uniprot id: A0A5B9PI77
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Part of the FGAM synthase complex composed of 1 PurL, 1 PurQ and 2 PurS subunits.
messages: Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL.

980251:MFFC18 RS05705
gene id: 980251:MFFC18_RS05705
uniprot id: A0A5B9P9P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980251:MFFC18 RS15275
gene id: 980251:MFFC18_RS15275
uniprot id: A0A5B9PM41
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

980251:MFFC18 RS04320
gene id: 980251:MFFC18_RS04320
uniprot id: A0A5B9P787
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS02060
gene id: 980251:MFFC18_RS02060
uniprot id: A0A5B9P343
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

980251:MFFC18 RS14910
gene id: 980251:MFFC18_RS14910
uniprot id: A0A5B9PDT3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05170
gene id: 980251:MFFC18_RS05170
uniprot id: A0A5B9PDX5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS20385
gene id: 980251:MFFC18_RS20385
uniprot id: A0A5B9PI87
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS03275
gene id: 980251:MFFC18_RS03275
uniprot id: A0A5B9PCG1
names: Similarity
names: Subunit
messages: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
messages: Homodimer.

980251:MFFC18 RS07055
gene id: 980251:MFFC18_RS07055
uniprot id: A0A5B9P8S6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

980251:MFFC18 RS02230
gene id: 980251:MFFC18_RS02230
uniprot id: A0A5B9P2N7
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS19875
gene id: 980251:MFFC18_RS19875
uniprot id: A0A5B9PGC5
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.

980251:MFFC18 RS11650
gene id: 980251:MFFC18_RS11650
uniprot id: A0A5B9PCG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA methyltransferase RsmE family.
messages: Cytoplasm
messages: Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.

980251:MFFC18 RS10565
gene id: 980251:MFFC18_RS10565
uniprot id: A0A5B9PBU3
names: Subcellular Location Annotation
messages: Cell inner membrane

980251:MFFC18 RS10245
gene id: 980251:MFFC18_RS10245
uniprot id: A0A5B9PHH0
names: Similarity
messages: Belongs to the polysaccharide synthase family.

980251:MFFC18 RS10315
gene id: 980251:MFFC18_RS10315
uniprot id: A0A5B9P6U9
names: Similarity
messages: Belongs to the polysaccharide synthase family.

980251:MFFC18 RS05140
gene id: 980251:MFFC18_RS05140
uniprot id: A0A5B9P7P9
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS13925
gene id: 980251:MFFC18_RS13925
uniprot id: A0A5B9PL59
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS21650
gene id: 980251:MFFC18_RS21650
uniprot id: A0A5B9PD01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

980251:MFFC18 RS15290
gene id: 980251:MFFC18_RS15290
uniprot id: A0A5B9PFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

980251:MFFC18 RS24645
gene id: 980251:MFFC18_RS24645
uniprot id: A0A5B9PFP6
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS08270
gene id: 980251:MFFC18_RS08270
uniprot id: A0A5B9PGI9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.

980251:MFFC18 RS05175
gene id: 980251:MFFC18_RS05175
uniprot id: A0A5B9P8J5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

980251:MFFC18 RS02965
gene id: 980251:MFFC18_RS02965
uniprot id: A0A5B9P2L8
names: Function
names: Similarity
messages: Belongs to the uricase family.
messages: Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.

980251:MFFC18 RS06795
gene id: 980251:MFFC18_RS06795
uniprot id: A0A5B9PF01
names: Function
names: Similarity
messages: Belongs to the peptidase S51 family.
messages: Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.

980251:MFFC18 RS02780
gene id: 980251:MFFC18_RS02780
uniprot id: A0A5B9P5F4
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

980251:MFFC18 RS02645
gene id: 980251:MFFC18_RS02645
uniprot id: A0A5B9P6Z0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

980251:MFFC18 RS06075
gene id: 980251:MFFC18_RS06075
uniprot id: A0A5B9P912
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

980251:MFFC18 RS03135
gene id: 980251:MFFC18_RS03135
uniprot id: A0A5B9P724
names: Similarity
messages: Belongs to the glutamine synthetase family.

980251:MFFC18 RS12215
gene id: 980251:MFFC18_RS12215
uniprot id: A0A5B9P7V3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

980251:MFFC18 RS14125
gene id: 980251:MFFC18_RS14125
uniprot id: A0A5B9PEU2
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

980251:MFFC18 RS15390
gene id: 980251:MFFC18_RS15390
uniprot id: A0A5B9PFH6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

980251:MFFC18 RS09550
gene id: 980251:MFFC18_RS09550
uniprot id: A0A5B9PB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

980251:MFFC18 RS11060
gene id: 980251:MFFC18_RS11060
uniprot id: A0A5B9P837
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

980251:MFFC18 RS12690
gene id: 980251:MFFC18_RS12690
uniprot id: A0A5B9PK11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

980251:MFFC18 RS11960
gene id: 980251:MFFC18_RS11960
uniprot id: A0A5B9P7Q1
names: Function
names: Similarity
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex.

980251:MFFC18 RS13115
gene id: 980251:MFFC18_RS13115
uniprot id: A0A5B9PKJ1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS02370
gene id: 980251:MFFC18_RS02370
uniprot id: A0A5B9P637
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS23075
gene id: 980251:MFFC18_RS23075
uniprot id: A0A5B9PFA8
names: Similarity
messages: Belongs to the peptidase C56 family.

980251:MFFC18 RS07835
gene id: 980251:MFFC18_RS07835
uniprot id: A0A5B9PA08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

980251:MFFC18 RS17080
gene id: 980251:MFFC18_RS17080
uniprot id: A0A5B9PAC5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05020
gene id: 980251:MFFC18_RS05020
uniprot id: A0A5B9PDU1
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

980251:MFFC18 RS02935
gene id: 980251:MFFC18_RS02935
uniprot id: A0A5B9PCC6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.

980251:MFFC18 RS16215
gene id: 980251:MFFC18_RS16215
uniprot id: A0A5B9PDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

980251:MFFC18 RS09355
gene id: 980251:MFFC18_RS09355
uniprot id: A0A5B9PB30
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrC family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980251:MFFC18 RS08450
gene id: 980251:MFFC18_RS08450
uniprot id: A0A5B9PAE9
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

980251:MFFC18 RS02070
gene id: 980251:MFFC18_RS02070
uniprot id: A0A5B9P7K9
names: Similarity
messages: Belongs to the FPG family.

980251:MFFC18 RS03830
gene id: 980251:MFFC18_RS03830
uniprot id: A0A5B9P613
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0161 family.
messages: Cell membrane
messages: Could be involved in insertion of integral membrane proteins into the membrane.

980251:MFFC18 RS02355
gene id: 980251:MFFC18_RS02355
uniprot id: A0A5B9P6K8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS17540
gene id: 980251:MFFC18_RS17540
uniprot id: A0A5B9PBX7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS06700
gene id: 980251:MFFC18_RS06700
uniprot id: A0A5B9P9D6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS12825
gene id: 980251:MFFC18_RS12825
uniprot id: A0A5B9P975
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

980251:MFFC18 RS22905
gene id: 980251:MFFC18_RS22905
uniprot id: A0A5B9PER7
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

980251:MFFC18 RS07355
gene id: 980251:MFFC18_RS07355
uniprot id: A0A5B9P9U4
names: Similarity
names: Subunit
messages: Belongs to the PanB family.
messages: Homodecamer; pentamer of dimers.

980251:MFFC18 RS02735
gene id: 980251:MFFC18_RS02735
uniprot id: A0A5B9P2X6
names: Similarity
messages: In the N-terminal section; belongs to the phytochrome family.

980251:MFFC18 RS14365
gene id: 980251:MFFC18_RS14365
uniprot id: A0A5B9PDA3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980251:MFFC18 RS09090
gene id: 980251:MFFC18_RS09090
uniprot id: A0A5B9P6Z6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS10710
gene id: 980251:MFFC18_RS10710
uniprot id: A0A5B9PBX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980251:MFFC18 RS01930
gene id: 980251:MFFC18_RS01930
uniprot id: A0A5B9P2I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S14 family.
messages: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.
messages: Cytoplasm
messages: Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

980251:MFFC18 RS10135
gene id: 980251:MFFC18_RS10135
uniprot id: A0A5B9PBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribonuclease III family.
messages: Cytoplasm
messages: Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
messages: Homodimer.

980251:MFFC18 RS04495
gene id: 980251:MFFC18_RS04495
uniprot id: A0A5B9P4D1
names: Similarity
messages: Belongs to the citrate synthase family.

980251:MFFC18 RS04805
gene id: 980251:MFFC18_RS04805
uniprot id: A0A5B9P422
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Cytoplasm
messages: Methylated by PrmC. Methylation increases the termination efficiency of RF1.
messages: Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.

980251:MFFC18 RS24485
gene id: 980251:MFFC18_RS24485
uniprot id: A0A5B9PIX5
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).

980251:MFFC18 RS00400
gene id: 980251:MFFC18_RS00400
uniprot id: A0A5B9P164
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

980251:MFFC18 RS13785
gene id: 980251:MFFC18_RS13785
uniprot id: A0A5B9P9Q3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

980251:MFFC18 RS15410
gene id: 980251:MFFC18_RS15410
uniprot id: A0A5B9PE23
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

980251:MFFC18 RS21035
gene id: 980251:MFFC18_RS21035
uniprot id: A0A5B9PIL7
names: Function
names: Similarity
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.

980251:MFFC18 RS17590
gene id: 980251:MFFC18_RS17590
uniprot id: A0A5B9PBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

980251:MFFC18 RS02550
gene id: 980251:MFFC18_RS02550
uniprot id: A0A5B9P6P8
names: Similarity
messages: Belongs to the peptidase S15 family.

980251:MFFC18 RS13405
gene id: 980251:MFFC18_RS13405
uniprot id: A0A5B9PKR2
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

980251:MFFC18 RS15230
gene id: 980251:MFFC18_RS15230
uniprot id: A0A5B9PAR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

980251:MFFC18 RS02240
gene id: 980251:MFFC18_RS02240
uniprot id: A0A5B9P6R7
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS04855
gene id: 980251:MFFC18_RS04855
uniprot id: A0A5B9P6K2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

980251:MFFC18 RS21975
gene id: 980251:MFFC18_RS21975
uniprot id: A0A5B9PEM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

980251:MFFC18 RS14090
gene id: 980251:MFFC18_RS14090
uniprot id: A0A5B9P9V4
names: Similarity
messages: Belongs to the type IA topoisomerase family.

980251:MFFC18 RS03020
gene id: 980251:MFFC18_RS03020
uniprot id: A0A5B9P5K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

980251:MFFC18 RS15335
gene id: 980251:MFFC18_RS15335
uniprot id: A0A5B9PDU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

980251:MFFC18 RS05665
gene id: 980251:MFFC18_RS05665
uniprot id: A0A5B9P4L2
names: Similarity
messages: Belongs to the UPF0145 family.

980251:MFFC18 RS17825
gene id: 980251:MFFC18_RS17825
uniprot id: A0A5B9PFA2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
messages: Cell membrane
messages: Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.

980251:MFFC18 RS09185
gene id: 980251:MFFC18_RS09185
uniprot id: A0A5B9PC59
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

980251:MFFC18 RS00960
gene id: 980251:MFFC18_RS00960
uniprot id: A0A5B9PB56
names: Similarity
messages: Belongs to the glutathione peroxidase family.

980251:MFFC18 RS24445
gene id: 980251:MFFC18_RS24445
uniprot id: A0A5B9PFL1
names: Cofactor
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS14595
gene id: 980251:MFFC18_RS14595
uniprot id: A0A5B9PE61
names: Similarity
messages: Belongs to the phosphohexose mutase family.

980251:MFFC18 RS04765
gene id: 980251:MFFC18_RS04765
uniprot id: A0A5B9P8F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferritin family. Prokaryotic subfamily.
messages: Cytoplasm
messages: Iron-storage protein.

980251:MFFC18 RS19770
gene id: 980251:MFFC18_RS19770
uniprot id: A0A5B9PGA9
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

980251:MFFC18 RS11615
gene id: 980251:MFFC18_RS11615
uniprot id: A0A5B9PBL5
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

980251:MFFC18 RS15360
gene id: 980251:MFFC18_RS15360
uniprot id: A0A5B9PE14
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

980251:MFFC18 RS18320
gene id: 980251:MFFC18_RS18320
uniprot id: A0A5B9PH83
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS24690
gene id: 980251:MFFC18_RS24690
uniprot id: A0A5B9PKP7
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

980251:MFFC18 RS19905
gene id: 980251:MFFC18_RS19905
uniprot id: A0A5B9PP10
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20515
gene id: 980251:MFFC18_RS20515
uniprot id: A0A5B9PPI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

980251:MFFC18 RS11630
gene id: 980251:MFFC18_RS11630
uniprot id: A0A5B9P8J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.
messages: Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.
messages: Monomer.

980251:MFFC18 RS05190
gene id: 980251:MFFC18_RS05190
uniprot id: A0A5B9P7R2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

980251:MFFC18 RS03645
gene id: 980251:MFFC18_RS03645
uniprot id: A0A5B9P7I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS06590
gene id: 980251:MFFC18_RS06590
uniprot id: A0A5B9P9E7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the pyridoxamine 5'-phosphate oxidase family.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS04600
gene id: 980251:MFFC18_RS04600
uniprot id: A0A5B9P907
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

980251:MFFC18 RS06105
gene id: 980251:MFFC18_RS06105
uniprot id: A0A5B9P462
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

980251:MFFC18 RS21970
gene id: 980251:MFFC18_RS21970
uniprot id: A0A5B9PQW1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

980251:MFFC18 RS17995
gene id: 980251:MFFC18_RS17995
uniprot id: A0A5B9PEH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

980251:MFFC18 RS22240
gene id: 980251:MFFC18_RS22240
uniprot id: A0A5B9PHI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS15225
gene id: 980251:MFFC18_RS15225
uniprot id: A0A5B9PM31
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

980251:MFFC18 RS17100
gene id: 980251:MFFC18_RS17100
uniprot id: A0A5B9PM59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS19870
gene id: 980251:MFFC18_RS19870
uniprot id: A0A5B9PD97
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Belongs to the type-I 3-dehydroquinase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
messages: Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS24420
gene id: 980251:MFFC18_RS24420
uniprot id: A0A5B9PSL9
names: Function
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.

980251:MFFC18 RS23580
gene id: 980251:MFFC18_RS23580
uniprot id: A0A5B9PF68
names: Similarity
messages: Belongs to the thioredoxin family.

980251:MFFC18 RS01125
gene id: 980251:MFFC18_RS01125
uniprot id: A0A5B9P723
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980251:MFFC18 RS19565
gene id: 980251:MFFC18_RS19565
uniprot id: A0A5B9PNU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPA3 antiporters (TC 2.A.63) subunit E family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS02675
gene id: 980251:MFFC18_RS02675
uniprot id: A0A5B9P7W9
names: Cofactor
names: Similarity
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.

980251:MFFC18 RS06195
gene id: 980251:MFFC18_RS06195
uniprot id: A0A5B9PAA8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

980251:MFFC18 RS08225
gene id: 980251:MFFC18_RS08225
uniprot id: A0A5B9P6G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

980251:MFFC18 RS05445
gene id: 980251:MFFC18_RS05445
uniprot id: A0A5B9P3W1
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidine kinase family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS20395
gene id: 980251:MFFC18_RS20395
uniprot id: A0A5B9PDD1
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

980251:MFFC18 RS07515
gene id: 980251:MFFC18_RS07515
uniprot id: A0A5B9P5Q0
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

980251:MFFC18 RS02490
gene id: 980251:MFFC18_RS02490
uniprot id: A0A5B9P6W4
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

980251:MFFC18 RS13470
gene id: 980251:MFFC18_RS13470
uniprot id: A0A5B9PEJ3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980251:MFFC18 RS11410
gene id: 980251:MFFC18_RS11410
uniprot id: A0A5B9PCA7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS11840
gene id: 980251:MFFC18_RS11840
uniprot id: A0A5B9PJC6
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

980251:MFFC18 RS19090
gene id: 980251:MFFC18_RS19090
uniprot id: A0A5B9PHD1
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

980251:MFFC18 RS17155
gene id: 980251:MFFC18_RS17155
uniprot id: A0A5B9PG51
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980251:MFFC18 RS17340
gene id: 980251:MFFC18_RS17340
uniprot id: A0A5B9PE57
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS06875
gene id: 980251:MFFC18_RS06875
uniprot id: A0A5B9P5A6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

980251:MFFC18 RS12880
gene id: 980251:MFFC18_RS12880
uniprot id: A0A5B9PCS9
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

980251:MFFC18 RS18740
gene id: 980251:MFFC18_RS18740
uniprot id: A0A5B9PND4
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

980251:MFFC18 RS04730
gene id: 980251:MFFC18_RS04730
uniprot id: A0A5B9P8A1
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

980251:MFFC18 RS20425
gene id: 980251:MFFC18_RS20425
uniprot id: A0A5B9PQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

980251:MFFC18 RS17795
gene id: 980251:MFFC18_RS17795
uniprot id: A0A5B9PED8
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

980251:MFFC18 RS02310
gene id: 980251:MFFC18_RS02310
uniprot id: A0A5B9P381
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS03525
gene id: 980251:MFFC18_RS03525
uniprot id: A0A5B9P6T0
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS19600
gene id: 980251:MFFC18_RS19600
uniprot id: A0A5B9PFA7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20100
gene id: 980251:MFFC18_RS20100
uniprot id: A0A5B9PFK1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS16945
gene id: 980251:MFFC18_RS16945
uniprot id: A0A5B9PEU5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnC family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2).

980251:MFFC18 RS03385
gene id: 980251:MFFC18_RS03385
uniprot id: A0A5B9P8B5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05595
gene id: 980251:MFFC18_RS05595
uniprot id: A0A5B9P9M3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS04400
gene id: 980251:MFFC18_RS04400
uniprot id: A0A5B9P7Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

980251:MFFC18 RS17415
gene id: 980251:MFFC18_RS17415
uniprot id: A0A5B9PNF5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
messages: Belongs to the FliW family.
messages: Cytoplasm
messages: Interacts with translational regulator CsrA and flagellin(s).

980251:MFFC18 RS03170
gene id: 980251:MFFC18_RS03170
uniprot id: A0A5B9PCH4
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS23630
gene id: 980251:MFFC18_RS23630
uniprot id: A0A5B9PHG7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00605
gene id: 980251:MFFC18_RS00605
uniprot id: A0A5B9P5T3
names: Similarity
messages: Belongs to the SurE nucleotidase family.

980251:MFFC18 RS12600
gene id: 980251:MFFC18_RS12600
uniprot id: A0A5B9PCC2
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS17390
gene id: 980251:MFFC18_RS17390
uniprot id: A0A5B9PBU0
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS02470
gene id: 980251:MFFC18_RS02470
uniprot id: A0A5B9P7U4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS07645
gene id: 980251:MFFC18_RS07645
uniprot id: A0A5B9P648
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.

980251:MFFC18 RS21360
gene id: 980251:MFFC18_RS21360
uniprot id: A0A5B9PCU8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

980251:MFFC18 RS13585
gene id: 980251:MFFC18_RS13585
uniprot id: A0A5B9PC07
names: Subcellular Location Annotation
messages: Cytoplasm

980251:MFFC18 RS24450
gene id: 980251:MFFC18_RS24450
uniprot id: A0A5B9PHY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas1 homodimer.

980251:MFFC18 RS03375
gene id: 980251:MFFC18_RS03375
uniprot id: A0A5B9P3S2
names: Similarity
messages: Belongs to the ABC transporter superfamily. Ycf16 family.

980251:MFFC18 RS01865
gene id: 980251:MFFC18_RS01865
uniprot id: A0A5B9P5U0
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00440
gene id: 980251:MFFC18_RS00440
uniprot id: A0A5B9P525
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS21475
gene id: 980251:MFFC18_RS21475
uniprot id: A0A5B9PQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980251:MFFC18 RS01790
gene id: 980251:MFFC18_RS01790
uniprot id: A0A5B9P6H5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS16265
gene id: 980251:MFFC18_RS16265
uniprot id: A0A5B9PEI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

980251:MFFC18 RS11265
gene id: 980251:MFFC18_RS11265
uniprot id: A0A5B9PD85
names: Similarity
messages: Belongs to the acylphosphatase family.

980251:MFFC18 RS07980
gene id: 980251:MFFC18_RS07980
uniprot id: A0A5B9P9A3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

980251:MFFC18 RS09365
gene id: 980251:MFFC18_RS09365
uniprot id: A0A5B9P746
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS17040
gene id: 980251:MFFC18_RS17040
uniprot id: A0A5B9PE00
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

980251:MFFC18 RS20215
gene id: 980251:MFFC18_RS20215
uniprot id: A0A5B9PI49
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Homodimer.

980251:MFFC18 RS20240
gene id: 980251:MFFC18_RS20240
uniprot id: A0A5B9PCA1
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS00770
gene id: 980251:MFFC18_RS00770
uniprot id: A0A5B9PB26
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

980251:MFFC18 RS10465
gene id: 980251:MFFC18_RS10465
uniprot id: A0A5B9PA51
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

980251:MFFC18 RS11125
gene id: 980251:MFFC18_RS11125
uniprot id: A0A5B9P791
names: Caution
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS12715
gene id: 980251:MFFC18_RS12715
uniprot id: A0A5B9P958
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaX/STICHEL family.
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.

980251:MFFC18 RS06660
gene id: 980251:MFFC18_RS06660
uniprot id: A0A5B9P5J6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

980251:MFFC18 RS01710
gene id: 980251:MFFC18_RS01710
uniprot id: A0A5B9PBJ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS11470
gene id: 980251:MFFC18_RS11470
uniprot id: A0A5B9P8A3
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS21535
gene id: 980251:MFFC18_RS21535
uniprot id: A0A5B9PQL9
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

980251:MFFC18 RS21545
gene id: 980251:MFFC18_RS21545
uniprot id: A0A5B9PH80
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS10665
gene id: 980251:MFFC18_RS10665
uniprot id: A0A5B9PIF4
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

980251:MFFC18 RS18550
gene id: 980251:MFFC18_RS18550
uniprot id: A0A5B9PNB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

980251:MFFC18 RS01100
gene id: 980251:MFFC18_RS01100
uniprot id: A0A5B9PB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980251:MFFC18 RS24460
gene id: 980251:MFFC18_RS24460
uniprot id: A0A5B9PRU0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the CRISPR-associated exonuclease Cas4 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).
messages: Mg(2+) or Mn(2+) required for ssDNA cleavage activity.

980251:MFFC18 RS18080
gene id: 980251:MFFC18_RS18080
uniprot id: A0A5B9PB24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
messages: Cytoplasm

980251:MFFC18 RS09525
gene id: 980251:MFFC18_RS09525
uniprot id: A0A5B9P6F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS25295
gene id: 980251:MFFC18_RS25295
uniprot id: A0A5B9PEU4
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS14460
gene id: 980251:MFFC18_RS14460
uniprot id: A0A5B9PAA6
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

980251:MFFC18 RS16860
gene id: 980251:MFFC18_RS16860
uniprot id: A0A5B9PFZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase Y family.
messages: Cell membrane
messages: Endoribonuclease that initiates mRNA decay.

980251:MFFC18 RS08285
gene id: 980251:MFFC18_RS08285
uniprot id: A0A5B9PBI1
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

980251:MFFC18 RS09585
gene id: 980251:MFFC18_RS09585
uniprot id: A0A5B9P9P3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS02320
gene id: 980251:MFFC18_RS02320
uniprot id: A0A5B9P7R3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980251:MFFC18 RS23810
gene id: 980251:MFFC18_RS23810
uniprot id: A0A5B9PHK8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS23290
gene id: 980251:MFFC18_RS23290
uniprot id: A0A5B9PF05
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

980251:MFFC18 RS06110
gene id: 980251:MFFC18_RS06110
uniprot id: A0A5B9P4U2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

980251:MFFC18 RS12190
gene id: 980251:MFFC18_RS12190
uniprot id: A0A5B9PCU7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

980251:MFFC18 RS06130
gene id: 980251:MFFC18_RS06130
uniprot id: A0A5B9P922
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

980251:MFFC18 RS20205
gene id: 980251:MFFC18_RS20205
uniprot id: A0A5B9PGG6
names: Similarity
messages: Belongs to the four-carbon acid sugar kinase family.

980251:MFFC18 RS07280
gene id: 980251:MFFC18_RS07280
uniprot id: A0A5B9P8W7
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS18220
gene id: 980251:MFFC18_RS18220
uniprot id: A0A5B9PFI5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

980251:MFFC18 RS19240
gene id: 980251:MFFC18_RS19240
uniprot id: A0A5B9PPF8
names: Similarity
messages: Belongs to the GARS family.

980251:MFFC18 RS00515
gene id: 980251:MFFC18_RS00515
uniprot id: A0A5B9PAW2
names: Similarity
messages: Belongs to the DNase I family.

980251:MFFC18 RS09275
gene id: 980251:MFFC18_RS09275
uniprot id: A0A5B9P729
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

980251:MFFC18 RS02360
gene id: 980251:MFFC18_RS02360
uniprot id: A0A5B9PBV5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS22825
gene id: 980251:MFFC18_RS22825
uniprot id: A0A5B9PQY0
names: Function
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.

980251:MFFC18 RS15395
gene id: 980251:MFFC18_RS15395
uniprot id: A0A5B9P9G6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

980251:MFFC18 RS02160
gene id: 980251:MFFC18_RS02160
uniprot id: A0A5B9PBR3
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS01260
gene id: 980251:MFFC18_RS01260
uniprot id: A0A5B9P5G9
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS15280
gene id: 980251:MFFC18_RS15280
uniprot id: A0A5B9PAS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

980251:MFFC18 RS08280
gene id: 980251:MFFC18_RS08280
uniprot id: A0A5B9P9G7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

980251:MFFC18 RS07535
gene id: 980251:MFFC18_RS07535
uniprot id: A0A5B9P9U5
names: Similarity
messages: Belongs to the UPF0178 family.

980251:MFFC18 RS03155
gene id: 980251:MFFC18_RS03155
uniprot id: A0A5B9P2Q2
names: Similarity
messages: Belongs to the UDPGP type 2 family.

980251:MFFC18 RS15270
gene id: 980251:MFFC18_RS15270
uniprot id: A0A5B9PEQ2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

980251:MFFC18 RS22215
gene id: 980251:MFFC18_RS22215
uniprot id: A0A5B9PER6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS12865
gene id: 980251:MFFC18_RS12865
uniprot id: A0A5B9PE67
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

980251:MFFC18 RS22210
gene id: 980251:MFFC18_RS22210
uniprot id: A0A5B9PR06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

980251:MFFC18 RS21930
gene id: 980251:MFFC18_RS21930
uniprot id: A0A5B9PHF5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00900
gene id: 980251:MFFC18_RS00900
uniprot id: A0A5B9P4C0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980251:MFFC18 RS01390
gene id: 980251:MFFC18_RS01390
uniprot id: A0A5B9PBE4
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS21920
gene id: 980251:MFFC18_RS21920
uniprot id: A0A5B9PQV1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS13200
gene id: 980251:MFFC18_RS13200
uniprot id: A0A5B9P9B5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

980251:MFFC18 RS05040
gene id: 980251:MFFC18_RS05040
uniprot id: A0A5B9P7M6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS22150
gene id: 980251:MFFC18_RS22150
uniprot id: A0A5B9PGK4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds 1 Fe(2+) cation per monomer.
messages: Binds 1 nickel ion per monomer.
messages: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Monomer.

980251:MFFC18 RS02400
gene id: 980251:MFFC18_RS02400
uniprot id: A0A5B9PC17
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

980251:MFFC18 RS16630
gene id: 980251:MFFC18_RS16630
uniprot id: A0A5B9PEL5
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

980251:MFFC18 RS18435
gene id: 980251:MFFC18_RS18435
uniprot id: A0A5B9PCG0
names: Similarity
messages: Belongs to the cytochrome P450 family.

980251:MFFC18 RS17185
gene id: 980251:MFFC18_RS17185
uniprot id: A0A5B9PBL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

980251:MFFC18 RS21625
gene id: 980251:MFFC18_RS21625
uniprot id: A0A5B9PIZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

980251:MFFC18 RS14890
gene id: 980251:MFFC18_RS14890
uniprot id: A0A5B9PF80
names: Function
names: Similarity
messages: Belongs to the sigma-70 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

980251:MFFC18 RS18905
gene id: 980251:MFFC18_RS18905
uniprot id: A0A5B9PCT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

980251:MFFC18 RS22245
gene id: 980251:MFFC18_RS22245
uniprot id: A0A5B9PQK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS15330
gene id: 980251:MFFC18_RS15330
uniprot id: A0A5B9PAS9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

980251:MFFC18 RS21785
gene id: 980251:MFFC18_RS21785
uniprot id: A0A5B9PEJ2
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

980251:MFFC18 RS17395
gene id: 980251:MFFC18_RS17395
uniprot id: A0A5B9PE66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-C family. DnaE2 subfamily.
messages: Cytoplasm
messages: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.

980251:MFFC18 RS06025
gene id: 980251:MFFC18_RS06025
uniprot id: A0A5B9PEE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.
messages: In the N-terminal section; belongs to the DHBP synthase family.

980251:MFFC18 RS06135
gene id: 980251:MFFC18_RS06135
uniprot id: A0A5B9PEU3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

980251:MFFC18 RS00540
gene id: 980251:MFFC18_RS00540
uniprot id: A0A5B9P6I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS00535
gene id: 980251:MFFC18_RS00535
uniprot id: A0A5B9P539
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

980251:MFFC18 RS16285
gene id: 980251:MFFC18_RS16285
uniprot id: A0A5B9PB99
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

980251:MFFC18 RS07830
gene id: 980251:MFFC18_RS07830
uniprot id: A0A5B9PFQ4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

980251:MFFC18 RS11510
gene id: 980251:MFFC18_RS11510
uniprot id: A0A5B9PCD2
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS06060
gene id: 980251:MFFC18_RS06060
uniprot id: A0A5B9P7D7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

980251:MFFC18 RS03280
gene id: 980251:MFFC18_RS03280
uniprot id: A0A5B9P3Q7
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

980251:MFFC18 RS07605
gene id: 980251:MFFC18_RS07605
uniprot id: A0A5B9PB39
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

980251:MFFC18 RS22235
gene id: 980251:MFFC18_RS22235
uniprot id: A0A5B9PGM6
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS21465
gene id: 980251:MFFC18_RS21465
uniprot id: A0A5B9PG75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS11680
gene id: 980251:MFFC18_RS11680
uniprot id: A0A5B9PAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S41B family.
messages: Cytoplasm

980251:MFFC18 RS00210
gene id: 980251:MFFC18_RS00210
uniprot id: A0A5B9P129
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

980251:MFFC18 RS14800
gene id: 980251:MFFC18_RS14800
uniprot id: A0A5B9P944
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

980251:MFFC18 RS13955
gene id: 980251:MFFC18_RS13955
uniprot id: A0A5B9PC74
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS10385
gene id: 980251:MFFC18_RS10385
uniprot id: A0A5B9PHJ7
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

980251:MFFC18 RS06090
gene id: 980251:MFFC18_RS06090
uniprot id: A0A5B9P559
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

980251:MFFC18 RS16045
gene id: 980251:MFFC18_RS16045
uniprot id: A0A5B9P9T5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS19170
gene id: 980251:MFFC18_RS19170
uniprot id: A0A5B9PF19
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS23390
gene id: 980251:MFFC18_RS23390
uniprot id: A0A5B9PHC5
names: Function
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.

980251:MFFC18 RS11990
gene id: 980251:MFFC18_RS11990
uniprot id: A0A5B9PJJ6
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

980251:MFFC18 RS20490
gene id: 980251:MFFC18_RS20490
uniprot id: A0A5B9PIA7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

980251:MFFC18 RS01135
gene id: 980251:MFFC18_RS01135
uniprot id: A0A5B9P238
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980251:MFFC18 RS03565
gene id: 980251:MFFC18_RS03565
uniprot id: A0A5B9P3V4
names: Function
names: Similarity
messages: Belongs to the helicase family. RecG subfamily.
messages: Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).

980251:MFFC18 RS05675
gene id: 980251:MFFC18_RS05675
uniprot id: A0A5B9P8W8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

980251:MFFC18 RS18725
gene id: 980251:MFFC18_RS18725
uniprot id: A0A5B9PCK7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

980251:MFFC18 RS12760
gene id: 980251:MFFC18_RS12760
uniprot id: A0A5B9P973
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS02710
gene id: 980251:MFFC18_RS02710
uniprot id: A0A5B9PC26
names: Similarity
messages: Belongs to the peptidase T1B family. HslV subfamily.

980251:MFFC18 RS22755
gene id: 980251:MFFC18_RS22755
uniprot id: A0A5B9PDU6
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS09310
gene id: 980251:MFFC18_RS09310
uniprot id: A0A5B9PB20
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS05270
gene id: 980251:MFFC18_RS05270
uniprot id: A0A5B9PDZ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

980251:MFFC18 RS19650
gene id: 980251:MFFC18_RS19650
uniprot id: A0A5B9PG70
names: Similarity
messages: Belongs to the threonine synthase family.

980251:MFFC18 RS19310
gene id: 980251:MFFC18_RS19310
uniprot id: A0A5B9PBR7
names: Similarity
messages: Belongs to the YciI family.

980251:MFFC18 RS02760
gene id: 980251:MFFC18_RS02760
uniprot id: A0A5B9P3G3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS18710
gene id: 980251:MFFC18_RS18710
uniprot id: A0A5B9PFS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS11460
gene id: 980251:MFFC18_RS11460
uniprot id: A0A5B9PCB8
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

980251:MFFC18 RS17500
gene id: 980251:MFFC18_RS17500
uniprot id: A0A5B9PF56
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

980251:MFFC18 RS02715
gene id: 980251:MFFC18_RS02715
uniprot id: A0A5B9P3F4
names: Similarity
messages: Belongs to the ClpX chaperone family. HslU subfamily.

980251:MFFC18 RS10510
gene id: 980251:MFFC18_RS10510
uniprot id: A0A5B9PHM7
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980251:MFFC18 RS21590
gene id: 980251:MFFC18_RS21590
uniprot id: A0A5B9PH90
names: Cofactor
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS20085
gene id: 980251:MFFC18_RS20085
uniprot id: A0A5B9PI25
names: Similarity
messages: Belongs to the DNA photolyase family.

980251:MFFC18 RS17955
gene id: 980251:MFFC18_RS17955
uniprot id: A0A5B9PMT5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS12770
gene id: 980251:MFFC18_RS12770
uniprot id: A0A5B9PCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

980251:MFFC18 RS24435
gene id: 980251:MFFC18_RS24435
uniprot id: A0A5B9PKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

980251:MFFC18 RS03860
gene id: 980251:MFFC18_RS03860
uniprot id: A0A5B9P702
names: Similarity
messages: Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.

980251:MFFC18 RS16710
gene id: 980251:MFFC18_RS16710
uniprot id: A0A5B9PLU3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

980251:MFFC18 RS18910
gene id: 980251:MFFC18_RS18910
uniprot id: A0A5B9PHH2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

980251:MFFC18 RS05305
gene id: 980251:MFFC18_RS05305
uniprot id: A0A5B9P4C8
names: Function
names: Similarity
messages: Belongs to the peptidase S46 family.
messages: Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.

980251:MFFC18 RS01150
gene id: 980251:MFFC18_RS01150
uniprot id: A0A5B9PB96
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

980251:MFFC18 RS00005
gene id: 980251:MFFC18_RS00005
uniprot id: A0A5B9P1N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

980251:MFFC18 RS11815
gene id: 980251:MFFC18_RS11815
uniprot id: A0A5B9P8N0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

980251:MFFC18 RS00745
gene id: 980251:MFFC18_RS00745
uniprot id: A0A5B9P1W7
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

980251:MFFC18 RS24620
gene id: 980251:MFFC18_RS24620
uniprot id: A0A5B9PSQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CutC family.
messages: Cytoplasm
messages: Once thought to be involved in copper homeostasis, experiments in E.coli have shown this is not the case.

980251:MFFC18 RS03835
gene id: 980251:MFFC18_RS03835
uniprot id: A0A5B9P7M5
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family.

980251:MFFC18 RS04590
gene id: 980251:MFFC18_RS04590
uniprot id: A0A5B9P4E3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS22695
gene id: 980251:MFFC18_RS22695
uniprot id: A0A5B9PHV5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS14615
gene id: 980251:MFFC18_RS14615
uniprot id: A0A5B9P906
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

980251:MFFC18 RS03445
gene id: 980251:MFFC18_RS03445
uniprot id: A0A5B9P3A0
names: Similarity
messages: Belongs to the anti-sigma-factor antagonist family.

980251:MFFC18 RS10140
gene id: 980251:MFFC18_RS10140
uniprot id: A0A5B9PI41
names: Similarity
messages: Belongs to the UPRTase family.

980251:MFFC18 RS03965
gene id: 980251:MFFC18_RS03965
uniprot id: A0A5B9P360
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS16580
gene id: 980251:MFFC18_RS16580
uniprot id: A0A5B9PBE9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS19845
gene id: 980251:MFFC18_RS19845
uniprot id: A0A5B9PGA5
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

980251:MFFC18 RS18330
gene id: 980251:MFFC18_RS18330
uniprot id: A0A5B9PCE1
names: Similarity
messages: Belongs to the YjdM family.

980251:MFFC18 RS14415
gene id: 980251:MFFC18_RS14415
uniprot id: A0A5B9PDB2
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.

980251:MFFC18 RS00160
gene id: 980251:MFFC18_RS00160
uniprot id: A0A5B9P121
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

980251:MFFC18 RS21255
gene id: 980251:MFFC18_RS21255
uniprot id: A0A5B9PCT1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
messages: Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS14370
gene id: 980251:MFFC18_RS14370
uniprot id: A0A5B9PEY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
messages: Cytoplasm
messages: GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.
messages: Monomer. Associates with the 50S ribosomal subunit.

980251:MFFC18 RS08580
gene id: 980251:MFFC18_RS08580
uniprot id: A0A5B9P5U2
names: Function
names: Similarity
messages: Belongs to the TrhO family.
messages: Belongs to the pseudouridine synthase RluA family.
messages: Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.

980251:MFFC18 RS14575
gene id: 980251:MFFC18_RS14575
uniprot id: A0A5B9PA30
names: Similarity
messages: Belongs to the threonine aldolase family.

980251:MFFC18 RS18640
gene id: 980251:MFFC18_RS18640
uniprot id: A0A5B9PHD6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS03420
gene id: 980251:MFFC18_RS03420
uniprot id: A0A5B9PCR7
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

980251:MFFC18 RS05115
gene id: 980251:MFFC18_RS05115
uniprot id: A0A5B9P8L9
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

980251:MFFC18 RS23905
gene id: 980251:MFFC18_RS23905
uniprot id: A0A5B9PFC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

980251:MFFC18 RS12170
gene id: 980251:MFFC18_RS12170
uniprot id: A0A5B9P8V2
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS17015
gene id: 980251:MFFC18_RS17015
uniprot id: A0A5B9PBS0
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

980251:MFFC18 RS05505
gene id: 980251:MFFC18_RS05505
uniprot id: A0A5B9P6Y1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980251:MFFC18 RS07470
gene id: 980251:MFFC18_RS07470
uniprot id: A0A5B9P5P0
names: Similarity
messages: Belongs to the FwdC/FmdC family.

980251:MFFC18 RS15400
gene id: 980251:MFFC18_RS15400
uniprot id: A0A5B9PAJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

980251:MFFC18 RS16705
gene id: 980251:MFFC18_RS16705
uniprot id: A0A5B9PEQ0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

980251:MFFC18 RS14825
gene id: 980251:MFFC18_RS14825
uniprot id: A0A5B9PEA8
names: Similarity
messages: Belongs to the citrate synthase family.

980251:MFFC18 RS04410
gene id: 980251:MFFC18_RS04410
uniprot id: A0A5B9P4B3
names: Similarity
messages: Belongs to the UPF0270 family.

980251:MFFC18 RS04620
gene id: 980251:MFFC18_RS04620
uniprot id: A0A5B9P8C7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS18115
gene id: 980251:MFFC18_RS18115
uniprot id: A0A5B9PCF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980251:MFFC18 RS02785
gene id: 980251:MFFC18_RS02785
uniprot id: A0A5B9P717
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

980251:MFFC18 RS00780
gene id: 980251:MFFC18_RS00780
uniprot id: A0A5B9P575
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.

980251:MFFC18 RS05925
gene id: 980251:MFFC18_RS05925
uniprot id: A0A5B9P914
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.

980251:MFFC18 RS09350
gene id: 980251:MFFC18_RS09350
uniprot id: A0A5B9PGU1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrB/RnfD family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980251:MFFC18 RS08890
gene id: 980251:MFFC18_RS08890
uniprot id: A0A5B9P6X4
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

980251:MFFC18 RS20160
gene id: 980251:MFFC18_RS20160
uniprot id: A0A5B9PP63
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS15145
gene id: 980251:MFFC18_RS15145
uniprot id: A0A5B9PDP8
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS14410
gene id: 980251:MFFC18_RS14410
uniprot id: A0A5B9PA96
names: Similarity
messages: Belongs to the histone deacetylase family.

980251:MFFC18 RS15425
gene id: 980251:MFFC18_RS15425
uniprot id: A0A5B9PM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

980251:MFFC18 RS13055
gene id: 980251:MFFC18_RS13055
uniprot id: A0A5B9P880
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rhamnose isomerase family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the interconversion of L-rhamnose and L-rhamnulose.
messages: Cytoplasm

980251:MFFC18 RS00165
gene id: 980251:MFFC18_RS00165
uniprot id: A0A5B9P1J8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

980251:MFFC18 RS11625
gene id: 980251:MFFC18_RS11625
uniprot id: A0A5B9P7I6
names: Function
names: Similarity
messages: Belongs to the helicase family. DnaB subfamily.
messages: Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.

980251:MFFC18 RS15620
gene id: 980251:MFFC18_RS15620
uniprot id: A0A5B9PE56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

980251:MFFC18 RS18375
gene id: 980251:MFFC18_RS18375
uniprot id: A0A5B9PH92
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS03490
gene id: 980251:MFFC18_RS03490
uniprot id: A0A5B9P2W8
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

980251:MFFC18 RS10285
gene id: 980251:MFFC18_RS10285
uniprot id: A0A5B9PBF8
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

980251:MFFC18 RS16030
gene id: 980251:MFFC18_RS16030
uniprot id: A0A5B9PB47
names: Similarity
messages: Belongs to the peptidase S1C family.

980251:MFFC18 RS18450
gene id: 980251:MFFC18_RS18450
uniprot id: A0A5B9PN90
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS11855
gene id: 980251:MFFC18_RS11855
uniprot id: A0A5B9PDJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm
messages: Mitochondrion

980251:MFFC18 RS24455
gene id: 980251:MFFC18_RS24455
uniprot id: A0A5B9PJ01
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CRISPR-associated endonuclease Cas1 family.
messages: CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
messages: Homodimer, forms a heterotetramer with a Cas2 homodimer.

980251:MFFC18 RS21115
gene id: 980251:MFFC18_RS21115
uniprot id: A0A5B9PDP9
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

980251:MFFC18 RS23980
gene id: 980251:MFFC18_RS23980
uniprot id: A0A5B9PIM9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase H family.
messages: Binds 2 metal ions per subunit. Manganese or magnesium.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

980251:MFFC18 RS21775
gene id: 980251:MFFC18_RS21775
uniprot id: A0A5B9PJ15
names: Subcellular Location Annotation
messages: Cell inner membrane

980251:MFFC18 RS20915
gene id: 980251:MFFC18_RS20915
uniprot id: A0A5B9PDL4
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

980251:MFFC18 RS24490
gene id: 980251:MFFC18_RS24490
uniprot id: A0A5B9PES0
names: Similarity
messages: In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.
messages: In the central section; belongs to the CRISPR-associated helicase Cas3 family.

980251:MFFC18 RS11935
gene id: 980251:MFFC18_RS11935
uniprot id: A0A5B9PCN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

980251:MFFC18 RS20770
gene id: 980251:MFFC18_RS20770
uniprot id: A0A5B9PDJ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecG family.
messages: Cell membrane
messages: Involved in protein export. Participates in an early event of protein translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

980251:MFFC18 RS11870
gene id: 980251:MFFC18_RS11870
uniprot id: A0A5B9PAX3
names: Similarity
messages: Belongs to the nitroreductase family.

980251:MFFC18 RS17790
gene id: 980251:MFFC18_RS17790
uniprot id: A0A5B9PC30
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Heterotrimer of A, B and C subunits.

980251:MFFC18 RS23410
gene id: 980251:MFFC18_RS23410
uniprot id: A0A5B9PRY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

980251:MFFC18 RS20720
gene id: 980251:MFFC18_RS20720
uniprot id: A0A5B9PDJ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS09025
gene id: 980251:MFFC18_RS09025
uniprot id: A0A5B9PGN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

980251:MFFC18 RS12265
gene id: 980251:MFFC18_RS12265
uniprot id: A0A5B9P7W0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

980251:MFFC18 RS12910
gene id: 980251:MFFC18_RS12910
uniprot id: A0A5B9PE76
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

980251:MFFC18 RS00585
gene id: 980251:MFFC18_RS00585
uniprot id: A0A5B9P546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NrfD family.
messages: Membrane

980251:MFFC18 RS24260
gene id: 980251:MFFC18_RS24260
uniprot id: A0A5B9PRQ1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.

980251:MFFC18 RS22960
gene id: 980251:MFFC18_RS22960
uniprot id: A0A5B9PH34
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS17760
gene id: 980251:MFFC18_RS17760
uniprot id: A0A5B9PGH4
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

980251:MFFC18 RS15200
gene id: 980251:MFFC18_RS15200
uniprot id: A0A5B9PAE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980251:MFFC18 RS08445
gene id: 980251:MFFC18_RS08445
uniprot id: A0A5B9P8Y3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

980251:MFFC18 RS12270
gene id: 980251:MFFC18_RS12270
uniprot id: A0A5B9P8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

980251:MFFC18 RS17755
gene id: 980251:MFFC18_RS17755
uniprot id: A0A5B9PMQ0
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

980251:MFFC18 RS01095
gene id: 980251:MFFC18_RS01095
uniprot id: A0A5B9P4E9
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

980251:MFFC18 RS05360
gene id: 980251:MFFC18_RS05360
uniprot id: A0A5B9P8R5
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

980251:MFFC18 RS05440
gene id: 980251:MFFC18_RS05440
uniprot id: A0A5B9P9J7
names: Similarity
messages: Belongs to the peptidase M13 family.

980251:MFFC18 RS01365
gene id: 980251:MFFC18_RS01365
uniprot id: A0A5B9P282
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS12175
gene id: 980251:MFFC18_RS12175
uniprot id: A0A5B9PB41
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M42 family.
messages: Binds 2 divalent metal cations per subunit.

980251:MFFC18 RS14590
gene id: 980251:MFFC18_RS14590
uniprot id: A0A5B9PKN2
names: Similarity
messages: Belongs to the phosphohexose mutase family.

980251:MFFC18 RS14565
gene id: 980251:MFFC18_RS14565
uniprot id: A0A5B9PF21
names: Function
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.

980251:MFFC18 RS11955
gene id: 980251:MFFC18_RS11955
uniprot id: A0A5B9PDN1
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

980251:MFFC18 RS07900
gene id: 980251:MFFC18_RS07900
uniprot id: A0A5B9PBA6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS23280
gene id: 980251:MFFC18_RS23280
uniprot id: A0A5B9PJY4
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

980251:MFFC18 RS18125
gene id: 980251:MFFC18_RS18125
uniprot id: A0A5B9PH42
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS13780
gene id: 980251:MFFC18_RS13780
uniprot id: A0A5B9P8K1
names: Function
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

980251:MFFC18 RS06560
gene id: 980251:MFFC18_RS06560
uniprot id: A0A5B9P5H4
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS08030
gene id: 980251:MFFC18_RS08030
uniprot id: A0A5B9P6C5
names: Similarity
messages: Belongs to the TrpF family.

980251:MFFC18 RS05700
gene id: 980251:MFFC18_RS05700
uniprot id: A0A5B9P7Z3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.
messages: Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).
messages: Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS08425
gene id: 980251:MFFC18_RS08425
uniprot id: A0A5B9P9J5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20420
gene id: 980251:MFFC18_RS20420
uniprot id: A0A5B9PI94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

980251:MFFC18 RS23745
gene id: 980251:MFFC18_RS23745
uniprot id: A0A5B9PIH5
names: Subunit
messages: Homodimer.

980251:MFFC18 RS00800
gene id: 980251:MFFC18_RS00800
uniprot id: A0A5B9P4A1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

980251:MFFC18 RS02055
gene id: 980251:MFFC18_RS02055
uniprot id: A0A5B9PBQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

980251:MFFC18 RS02315
gene id: 980251:MFFC18_RS02315
uniprot id: A0A5B9P628
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS18540
gene id: 980251:MFFC18_RS18540
uniprot id: A0A5B9PFP7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS02850
gene id: 980251:MFFC18_RS02850
uniprot id: A0A5B9P3I1
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980251:MFFC18 RS02970
gene id: 980251:MFFC18_RS02970
uniprot id: A0A5B9P318
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homotetramer.

980251:MFFC18 RS19490
gene id: 980251:MFFC18_RS19490
uniprot id: A0A5B9PBV4
names: Similarity
messages: Belongs to the CutA family.

980251:MFFC18 RS09595
gene id: 980251:MFFC18_RS09595
uniprot id: A0A5B9PH53
names: Similarity
messages: Belongs to the FTR family.

980251:MFFC18 RS21855
gene id: 980251:MFFC18_RS21855
uniprot id: A0A5B9PHB8
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS12695
gene id: 980251:MFFC18_RS12695
uniprot id: A0A5B9P8Z5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M32 family.
messages: Binds 1 zinc ion per subunit.
messages: Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.

980251:MFFC18 RS20535
gene id: 980251:MFFC18_RS20535
uniprot id: A0A5B9PGQ6
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

980251:MFFC18 RS05155
gene id: 980251:MFFC18_RS05155
uniprot id: A0A5B9P499
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS09645
gene id: 980251:MFFC18_RS09645
uniprot id: A0A5B9PH62
names: Similarity
messages: Belongs to the MoaD family.

980251:MFFC18 RS18530
gene id: 980251:MFFC18_RS18530
uniprot id: A0A5B9PCI4
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

980251:MFFC18 RS11215
gene id: 980251:MFFC18_RS11215
uniprot id: A0A5B9PD76
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00010
gene id: 980251:MFFC18_RS00010
uniprot id: A0A5B9P4T8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

980251:MFFC18 RS13170
gene id: 980251:MFFC18_RS13170
uniprot id: A0A5B9PED6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS22225
gene id: 980251:MFFC18_RS22225
uniprot id: A0A5B9PJC7
names: Similarity
messages: Belongs to the pyruvate kinase family.

980251:MFFC18 RS05035
gene id: 980251:MFFC18_RS05035
uniprot id: A0A5B9P4K3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

980251:MFFC18 RS12790
gene id: 980251:MFFC18_RS12790
uniprot id: A0A5B9PD62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

980251:MFFC18 RS03535
gene id: 980251:MFFC18_RS03535
uniprot id: A0A5B9P2X9
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

980251:MFFC18 RS12605
gene id: 980251:MFFC18_RS12605
uniprot id: A0A5B9PE18
names: Similarity
messages: Belongs to the group II decarboxylase family.

980251:MFFC18 RS22000
gene id: 980251:MFFC18_RS22000
uniprot id: A0A5B9PGH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

980251:MFFC18 RS07735
gene id: 980251:MFFC18_RS07735
uniprot id: A0A5B9P9Y5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reduced FMN (FMNH(2)).

980251:MFFC18 RS10770
gene id: 980251:MFFC18_RS10770
uniprot id: A0A5B9P815
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS20030
gene id: 980251:MFFC18_RS20030
uniprot id: A0A5B9PGF6
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS14500
gene id: 980251:MFFC18_RS14500
uniprot id: A0A5B9PE39
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS17735
gene id: 980251:MFFC18_RS17735
uniprot id: A0A5B9PAR4
names: Similarity
messages: Belongs to the Nudix hydrolase family.

980251:MFFC18 RS02350
gene id: 980251:MFFC18_RS02350
uniprot id: A0A5B9PC09
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS09555
gene id: 980251:MFFC18_RS09555
uniprot id: A0A5B9PHQ5
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

980251:MFFC18 RS23325
gene id: 980251:MFFC18_RS23325
uniprot id: A0A5B9PJZ3
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS15140
gene id: 980251:MFFC18_RS15140
uniprot id: A0A5B9PAP3
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

980251:MFFC18 RS05895
gene id: 980251:MFFC18_RS05895
uniprot id: A0A5B9P518
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

980251:MFFC18 RS21340
gene id: 980251:MFFC18_RS21340
uniprot id: A0A5B9PQI0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

980251:MFFC18 RS11770
gene id: 980251:MFFC18_RS11770
uniprot id: A0A5B9P8M1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS19820
gene id: 980251:MFFC18_RS19820
uniprot id: A0A5B9PGB7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS17605
gene id: 980251:MFFC18_RS17605
uniprot id: A0A5B9PML8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS21620
gene id: 980251:MFFC18_RS21620
uniprot id: A0A5B9PQ85
names: Similarity
messages: Belongs to the RecJ family.

980251:MFFC18 RS17115
gene id: 980251:MFFC18_RS17115
uniprot id: A0A5B9PBU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

980251:MFFC18 RS00875
gene id: 980251:MFFC18_RS00875
uniprot id: A0A5B9P2A9
names: Similarity
messages: Belongs to the IlvD/Edd family.

980251:MFFC18 RS00915
gene id: 980251:MFFC18_RS00915
uniprot id: A0A5B9P5T5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS15695
gene id: 980251:MFFC18_RS15695
uniprot id: A0A5B9PE21
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980251:MFFC18 RS02575
gene id: 980251:MFFC18_RS02575
uniprot id: A0A5B9P2E5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS03725
gene id: 980251:MFFC18_RS03725
uniprot id: A0A5B9P316
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

980251:MFFC18 RS19425
gene id: 980251:MFFC18_RS19425
uniprot id: A0A5B9PHP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980251:MFFC18 RS04700
gene id: 980251:MFFC18_RS04700
uniprot id: A0A5B9P925
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

980251:MFFC18 RS13575
gene id: 980251:MFFC18_RS13575
uniprot id: A0A5B9P8G8
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily.

980251:MFFC18 RS19715
gene id: 980251:MFFC18_RS19715
uniprot id: A0A5B9PD64
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS14530
gene id: 980251:MFFC18_RS14530
uniprot id: A0A5B9PCI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Forms a complex with TatC.
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.

980251:MFFC18 RS04675
gene id: 980251:MFFC18_RS04675
uniprot id: A0A5B9PDM0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

980251:MFFC18 RS19925
gene id: 980251:MFFC18_RS19925
uniprot id: A0A5B9PGD5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS06835
gene id: 980251:MFFC18_RS06835
uniprot id: A0A5B9P7T0
names: Similarity
messages: Belongs to the N-acylglucosamine 2-epimerase family.

980251:MFFC18 RS15320
gene id: 980251:MFFC18_RS15320
uniprot id: A0A5B9PER2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane

980251:MFFC18 RS05720
gene id: 980251:MFFC18_RS05720
uniprot id: A0A5B9P714
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

980251:MFFC18 RS08250
gene id: 980251:MFFC18_RS08250
uniprot id: A0A5B9P8U8
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

980251:MFFC18 RS10990
gene id: 980251:MFFC18_RS10990
uniprot id: A0A5B9PI29
names: Similarity
messages: Belongs to the alpha-acetolactate decarboxylase family.

980251:MFFC18 RS08275
gene id: 980251:MFFC18_RS08275
uniprot id: A0A5B9P6H3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

980251:MFFC18 RS02020
gene id: 980251:MFFC18_RS02020
uniprot id: A0A5B9P7J7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS16965
gene id: 980251:MFFC18_RS16965
uniprot id: A0A5B9PBQ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

980251:MFFC18 RS05475
gene id: 980251:MFFC18_RS05475
uniprot id: A0A5B9PEB3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

980251:MFFC18 RS05245
gene id: 980251:MFFC18_RS05245
uniprot id: A0A5B9P9G2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-3 integral membrane protein family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS19595
gene id: 980251:MFFC18_RS19595
uniprot id: A0A5B9PBX0
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS23115
gene id: 980251:MFFC18_RS23115
uniprot id: A0A5B9PRS3
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980251:MFFC18 RS00130
gene id: 980251:MFFC18_RS00130
uniprot id: A0A5B9PAP9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS14355
gene id: 980251:MFFC18_RS14355
uniprot id: A0A5B9PLF6
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

980251:MFFC18 RS20665
gene id: 980251:MFFC18_RS20665
uniprot id: A0A5B9PFT9
names: Similarity
messages: Belongs to the ribF family.

980251:MFFC18 RS06600
gene id: 980251:MFFC18_RS06600
uniprot id: A0A5B9P9B7
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS16905
gene id: 980251:MFFC18_RS16905
uniprot id: A0A5B9PG09
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

980251:MFFC18 RS21565
gene id: 980251:MFFC18_RS21565
uniprot id: A0A5B9PH56
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoD/SigA subfamily.
messages: Cytoplasm
messages: Interacts transiently with the RNA polymerase catalytic core.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.

980251:MFFC18 RS01580
gene id: 980251:MFFC18_RS01580
uniprot id: A0A5B9PBH8
names: Similarity
messages: Belongs to the ComB family.

980251:MFFC18 RS03695
gene id: 980251:MFFC18_RS03695
uniprot id: A0A5B9P7J1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS18585
gene id: 980251:MFFC18_RS18585
uniprot id: A0A5B9PCN4
names: Subunit
messages: Homodimer.

980251:MFFC18 RS01985
gene id: 980251:MFFC18_RS01985
uniprot id: A0A5B9P503
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS23735
gene id: 980251:MFFC18_RS23735
uniprot id: A0A5B9PS81
names: Similarity
messages: Belongs to the GPI family.

980251:MFFC18 RS10280
gene id: 980251:MFFC18_RS10280
uniprot id: A0A5B9PA24
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980251:MFFC18 RS01785
gene id: 980251:MFFC18_RS01785
uniprot id: A0A5B9P7E8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

980251:MFFC18 RS02095
gene id: 980251:MFFC18_RS02095
uniprot id: A0A5B9PBV6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS01860
gene id: 980251:MFFC18_RS01860
uniprot id: A0A5B9P309
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS24300
gene id: 980251:MFFC18_RS24300
uniprot id: A0A5B9PHV6
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

980251:MFFC18 RS11480
gene id: 980251:MFFC18_RS11480
uniprot id: A0A5B9PDC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

980251:MFFC18 RS05195
gene id: 980251:MFFC18_RS05195
uniprot id: A0A5B9P9B2
names: Similarity
messages: Belongs to the formate--tetrahydrofolate ligase family.

980251:MFFC18 RS23305
gene id: 980251:MFFC18_RS23305
uniprot id: A0A5B9PJU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

980251:MFFC18 RS06585
gene id: 980251:MFFC18_RS06585
uniprot id: A0A5B9P7N2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS20440
gene id: 980251:MFFC18_RS20440
uniprot id: A0A5B9PI98
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

980251:MFFC18 RS01680
gene id: 980251:MFFC18_RS01680
uniprot id: A0A5B9P2X1
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

980251:MFFC18 RS07320
gene id: 980251:MFFC18_RS07320
uniprot id: A0A5B9PFL4
names: Similarity
messages: Belongs to the metallophosphoesterase superfamily. YfcE family.

980251:MFFC18 RS06015
gene id: 980251:MFFC18_RS06015
uniprot id: A0A5B9P7C6
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

980251:MFFC18 RS00790
gene id: 980251:MFFC18_RS00790
uniprot id: A0A5B9P1C3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

980251:MFFC18 RS17700
gene id: 980251:MFFC18_RS17700
uniprot id: A0A5B9PF93
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS09315
gene id: 980251:MFFC18_RS09315
uniprot id: A0A5B9PHI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.
messages: Membrane

980251:MFFC18 RS08075
gene id: 980251:MFFC18_RS08075
uniprot id: A0A5B9PGF0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

980251:MFFC18 RS17470
gene id: 980251:MFFC18_RS17470
uniprot id: A0A5B9PC15
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

980251:MFFC18 RS19590
gene id: 980251:MFFC18_RS19590
uniprot id: A0A5B9PHT2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05110
gene id: 980251:MFFC18_RS05110
uniprot id: A0A5B9P6P9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

980251:MFFC18 RS06555
gene id: 980251:MFFC18_RS06555
uniprot id: A0A5B9PF34
names: Similarity
messages: Belongs to the ABC transporter superfamily.

980251:MFFC18 RS03970
gene id: 980251:MFFC18_RS03970
uniprot id: A0A5B9P3K3
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

980251:MFFC18 RS07115
gene id: 980251:MFFC18_RS07115
uniprot id: A0A5B9P4U6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980251:MFFC18 RS21185
gene id: 980251:MFFC18_RS21185
uniprot id: A0A5B9PQF5
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

980251:MFFC18 RS16380
gene id: 980251:MFFC18_RS16380
uniprot id: A0A5B9PMP3
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

980251:MFFC18 RS09340
gene id: 980251:MFFC18_RS09340
uniprot id: A0A5B9P9K1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980251:MFFC18 RS21765
gene id: 980251:MFFC18_RS21765
uniprot id: A0A5B9PH96
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS17020
gene id: 980251:MFFC18_RS17020
uniprot id: A0A5B9PET5
names: Similarity
messages: Belongs to the peptidase M10B family.

980251:MFFC18 RS16910
gene id: 980251:MFFC18_RS16910
uniprot id: A0A5B9PN00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

980251:MFFC18 RS10965
gene id: 980251:MFFC18_RS10965
uniprot id: A0A5B9PD37
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS16375
gene id: 980251:MFFC18_RS16375
uniprot id: A0A5B9PFJ3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

980251:MFFC18 RS14235
gene id: 980251:MFFC18_RS14235
uniprot id: A0A5B9PCD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

980251:MFFC18 RS09490
gene id: 980251:MFFC18_RS09490
uniprot id: A0A5B9PB04
names: Similarity
messages: Belongs to the glycosyl hydrolase 20 family.

980251:MFFC18 RS09485
gene id: 980251:MFFC18_RS09485
uniprot id: A0A5B9P9M5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS18150
gene id: 980251:MFFC18_RS18150
uniprot id: A0A5B9PN39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

980251:MFFC18 RS15340
gene id: 980251:MFFC18_RS15340
uniprot id: A0A5B9PFG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

980251:MFFC18 RS14515
gene id: 980251:MFFC18_RS14515
uniprot id: A0A5B9PDD4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

980251:MFFC18 RS12395
gene id: 980251:MFFC18_RS12395
uniprot id: A0A5B9PJU5
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS15600
gene id: 980251:MFFC18_RS15600
uniprot id: A0A5B9PFL7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS11120
gene id: 980251:MFFC18_RS11120
uniprot id: A0A5B9PD61
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

980251:MFFC18 RS11505
gene id: 980251:MFFC18_RS11505
uniprot id: A0A5B9PIJ9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

980251:MFFC18 RS06070
gene id: 980251:MFFC18_RS06070
uniprot id: A0A5B9PEF1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

980251:MFFC18 RS22160
gene id: 980251:MFFC18_RS22160
uniprot id: A0A5B9PQI2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Monomer.

980251:MFFC18 RS12290
gene id: 980251:MFFC18_RS12290
uniprot id: A0A5B9PCW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980251:MFFC18 RS19915
gene id: 980251:MFFC18_RS19915
uniprot id: A0A5B9PPT2
names: Caution
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

980251:MFFC18 RS19225
gene id: 980251:MFFC18_RS19225
uniprot id: A0A5B9PG02
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS24145
gene id: 980251:MFFC18_RS24145
uniprot id: A0A5B9PHT3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS23970
gene id: 980251:MFFC18_RS23970
uniprot id: A0A5B9PSD3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS11355
gene id: 980251:MFFC18_RS11355
uniprot id: A0A5B9PIG3
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.

980251:MFFC18 RS03950
gene id: 980251:MFFC18_RS03950
uniprot id: A0A5B9P427
names: Similarity
messages: Belongs to the peptidase A24 family.

980251:MFFC18 RS12535
gene id: 980251:MFFC18_RS12535
uniprot id: A0A5B9PJX6
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS23685
gene id: 980251:MFFC18_RS23685
uniprot id: A0A5B9PS72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

980251:MFFC18 RS00560
gene id: 980251:MFFC18_RS00560
uniprot id: A0A5B9P5S3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Cell membrane
messages: Membrane
messages: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).

980251:MFFC18 RS01130
gene id: 980251:MFFC18_RS01130
uniprot id: A0A5B9P1J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS04315
gene id: 980251:MFFC18_RS04315
uniprot id: A0A5B9PDE8
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

980251:MFFC18 RS11370
gene id: 980251:MFFC18_RS11370
uniprot id: A0A5B9P888
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS23030
gene id: 980251:MFFC18_RS23030
uniprot id: A0A5B9PF97
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00810
gene id: 980251:MFFC18_RS00810
uniprot id: A0A5B9PB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

980251:MFFC18 RS20785
gene id: 980251:MFFC18_RS20785
uniprot id: A0A5B9PPQ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

980251:MFFC18 RS10955
gene id: 980251:MFFC18_RS10955
uniprot id: A0A5B9P823
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

980251:MFFC18 RS21055
gene id: 980251:MFFC18_RS21055
uniprot id: A0A5B9PIK0
names: Similarity
messages: Belongs to the creatininase superfamily.

980251:MFFC18 RS17985
gene id: 980251:MFFC18_RS17985
uniprot id: A0A5B9PB09
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapB family.
messages: Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
messages: Cytoplasm
messages: Homotetramer.
messages: Was originally thought to be a dihydrodipicolinate reductase (DHDPR), catalyzing the conversion of dihydrodipicolinate to tetrahydrodipicolinate. However, it was shown in E.coli that the substrate of the enzymatic reaction is not dihydrodipicolinate (DHDP) but in fact (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinic acid (HTPA), the product released by the DapA-catalyzed reaction.

980251:MFFC18 RS05185
gene id: 980251:MFFC18_RS05185
uniprot id: A0A5B9P4M5
names: Similarity
messages: Belongs to the aspartokinase family.

980251:MFFC18 RS01215
gene id: 980251:MFFC18_RS01215
uniprot id: A0A5B9P5G1
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS22915
gene id: 980251:MFFC18_RS22915
uniprot id: A0A5B9PHY4
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS13890
gene id: 980251:MFFC18_RS13890
uniprot id: A0A5B9PC64
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS02075
gene id: 980251:MFFC18_RS02075
uniprot id: A0A5B9P246
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

980251:MFFC18 RS10130
gene id: 980251:MFFC18_RS10130
uniprot id: A0A5B9PHF4
names: Similarity
messages: Belongs to the class-II DAHP synthase family.

980251:MFFC18 RS19865
gene id: 980251:MFFC18_RS19865
uniprot id: A0A5B9PPS3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS06905
gene id: 980251:MFFC18_RS06905
uniprot id: A0A5B9P5P7
names: Similarity
messages: Belongs to the UPF0047 family.

980251:MFFC18 RS23500
gene id: 980251:MFFC18_RS23500
uniprot id: A0A5B9PIA6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS05565
gene id: 980251:MFFC18_RS05565
uniprot id: A0A5B9PE58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

980251:MFFC18 RS02185
gene id: 980251:MFFC18_RS02185
uniprot id: A0A5B9P2M8
names: Function
names: Similarity
messages: Belongs to the DHPS family.
messages: Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.

980251:MFFC18 RS17495
gene id: 980251:MFFC18_RS17495
uniprot id: A0A5B9PE84
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS15895
gene id: 980251:MFFC18_RS15895
uniprot id: A0A5B9PFS4
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS03985
gene id: 980251:MFFC18_RS03985
uniprot id: A0A5B9PD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

980251:MFFC18 RS16890
gene id: 980251:MFFC18_RS16890
uniprot id: A0A5B9PBG1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

980251:MFFC18 RS11970
gene id: 980251:MFFC18_RS11970
uniprot id: A0A5B9PAZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-transferase family. Bpt subfamily.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate.

980251:MFFC18 RS13970
gene id: 980251:MFFC18_RS13970
uniprot id: A0A5B9PL71
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.

980251:MFFC18 RS23385
gene id: 980251:MFFC18_RS23385
uniprot id: A0A5B9PF29
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS11405
gene id: 980251:MFFC18_RS11405
uniprot id: A0A5B9PIH6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS01395
gene id: 980251:MFFC18_RS01395
uniprot id: A0A5B9P2R6
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS01505
gene id: 980251:MFFC18_RS01505
uniprot id: A0A5B9P2A6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS06255
gene id: 980251:MFFC18_RS06255
uniprot id: A0A5B9P497
names: Subcellular Location Annotation
messages: Cell inner membrane

980251:MFFC18 RS23880
gene id: 980251:MFFC18_RS23880
uniprot id: A0A5B9PSB3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

980251:MFFC18 RS02745
gene id: 980251:MFFC18_RS02745
uniprot id: A0A5B9PC84
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS23560
gene id: 980251:MFFC18_RS23560
uniprot id: A0A5B9PFI3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS24520
gene id: 980251:MFFC18_RS24520
uniprot id: A0A5B9PSN9
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS23640
gene id: 980251:MFFC18_RS23640
uniprot id: A0A5B9PRC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

980251:MFFC18 RS23285
gene id: 980251:MFFC18_RS23285
uniprot id: A0A5B9PE55
names: Similarity
messages: Belongs to the P(II) protein family.

980251:MFFC18 RS01840
gene id: 980251:MFFC18_RS01840
uniprot id: A0A5B9P6I6
names: Similarity
messages: Belongs to the AAA ATPase family.

980251:MFFC18 RS03690
gene id: 980251:MFFC18_RS03690
uniprot id: A0A5B9P5Y1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980251:MFFC18 RS12915
gene id: 980251:MFFC18_RS12915
uniprot id: A0A5B9P858
names: Similarity
messages: Belongs to the UPF0235 family.

980251:MFFC18 RS08415
gene id: 980251:MFFC18_RS08415
uniprot id: A0A5B9PAB7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS18415
gene id: 980251:MFFC18_RS18415
uniprot id: A0A5B9PCK8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

980251:MFFC18 RS03650
gene id: 980251:MFFC18_RS03650
uniprot id: A0A5B9PCY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980251:MFFC18 RS13900
gene id: 980251:MFFC18_RS13900
uniprot id: A0A5B9PK95
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

980251:MFFC18 RS06990
gene id: 980251:MFFC18_RS06990
uniprot id: A0A5B9P9I2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS23725
gene id: 980251:MFFC18_RS23725
uniprot id: A0A5B9PRE3
names: Similarity
messages: Belongs to the UPF0173 family.

980251:MFFC18 RS02235
gene id: 980251:MFFC18_RS02235
uniprot id: A0A5B9P550
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS06100
gene id: 980251:MFFC18_RS06100
uniprot id: A0A5B9PA87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

980251:MFFC18 RS03075
gene id: 980251:MFFC18_RS03075
uniprot id: A0A5B9P768
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

980251:MFFC18 RS00350
gene id: 980251:MFFC18_RS00350
uniprot id: A0A5B9P156
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS01105
gene id: 980251:MFFC18_RS01105
uniprot id: A0A5B9P5W9
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS02865
gene id: 980251:MFFC18_RS02865
uniprot id: A0A5B9P2K1
names: Similarity
messages: Belongs to the peptidase M16 family.

980251:MFFC18 RS08870
gene id: 980251:MFFC18_RS08870
uniprot id: A0A5B9PH46
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS15220
gene id: 980251:MFFC18_RS15220
uniprot id: A0A5B9PEJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

980251:MFFC18 RS12365
gene id: 980251:MFFC18_RS12365
uniprot id: A0A5B9PDW7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS05910
gene id: 980251:MFFC18_RS05910
uniprot id: A0A5B9P435
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ApbE family.
messages: Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.
messages: Magnesium. Can also use manganese.

980251:MFFC18 RS23140
gene id: 980251:MFFC18_RS23140
uniprot id: A0A5B9PE34
names: Similarity
messages: Belongs to the type IB topoisomerase family.

980251:MFFC18 RS05600
gene id: 980251:MFFC18_RS05600
uniprot id: A0A5B9P3Y6
names: Similarity
messages: Belongs to the CinA family.

980251:MFFC18 RS18090
gene id: 980251:MFFC18_RS18090
uniprot id: A0A5B9PEJ7
names: Similarity
messages: Belongs to the peptidase S41A family.

980251:MFFC18 RS06530
gene id: 980251:MFFC18_RS06530
uniprot id: A0A5B9P4J0
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS21490
gene id: 980251:MFFC18_RS21490
uniprot id: A0A5B9PEE0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS04440
gene id: 980251:MFFC18_RS04440
uniprot id: A0A5B9P7Z1
names: Similarity
messages: Belongs to the HisA/HisF family.

980251:MFFC18 RS09230
gene id: 980251:MFFC18_RS09230
uniprot id: A0A5B9PA53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CitM (TC 2.A.11) transporter family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS20285
gene id: 980251:MFFC18_RS20285
uniprot id: A0A5B9PI68
names: Similarity
messages: Belongs to the peptidase A24 family.

980251:MFFC18 RS07100
gene id: 980251:MFFC18_RS07100
uniprot id: A0A5B9P5T9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP38/TMEM64 family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS12800
gene id: 980251:MFFC18_RS12800
uniprot id: A0A5B9P915
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

980251:MFFC18 RS13440
gene id: 980251:MFFC18_RS13440
uniprot id: A0A5B9PD35
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

980251:MFFC18 RS08555
gene id: 980251:MFFC18_RS08555
uniprot id: A0A5B9PAE8
names: Similarity
messages: Belongs to the TrpC family.

980251:MFFC18 RS05500
gene id: 980251:MFFC18_RS05500
uniprot id: A0A5B9P4J4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS22985
gene id: 980251:MFFC18_RS22985
uniprot id: A0A5B9PF89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

980251:MFFC18 RS19360
gene id: 980251:MFFC18_RS19360
uniprot id: A0A5B9PCV5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

980251:MFFC18 RS10305
gene id: 980251:MFFC18_RS10305
uniprot id: A0A5B9PAX2
names: Similarity
messages: Belongs to the bacterial sugar transferase family.

980251:MFFC18 RS21835
gene id: 980251:MFFC18_RS21835
uniprot id: A0A5B9PHD8
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS21655
gene id: 980251:MFFC18_RS21655
uniprot id: A0A5B9PE04
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS11135
gene id: 980251:MFFC18_RS11135
uniprot id: A0A5B9PAJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

980251:MFFC18 RS11225
gene id: 980251:MFFC18_RS11225
uniprot id: A0A5B9P8B0
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

980251:MFFC18 RS23135
gene id: 980251:MFFC18_RS23135
uniprot id: A0A5B9PJV7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS21955
gene id: 980251:MFFC18_RS21955
uniprot id: A0A5B9PHD7
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS15285
gene id: 980251:MFFC18_RS15285
uniprot id: A0A5B9PDT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Membrane

980251:MFFC18 RS01660
gene id: 980251:MFFC18_RS01660
uniprot id: A0A5B9P6F0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial sugar transferase family.
messages: Membrane

980251:MFFC18 RS00115
gene id: 980251:MFFC18_RS00115
uniprot id: A0A5B9P1I8
names: Similarity
messages: Belongs to the glutamate synthase family.

980251:MFFC18 RS17780
gene id: 980251:MFFC18_RS17780
uniprot id: A0A5B9PGY6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

980251:MFFC18 RS17610
gene id: 980251:MFFC18_RS17610
uniprot id: A0A5B9PGE2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS10535
gene id: 980251:MFFC18_RS10535
uniprot id: A0A5B9PCW1
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Homodimer.

980251:MFFC18 RS04980
gene id: 980251:MFFC18_RS04980
uniprot id: A0A5B9P8F7
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

980251:MFFC18 RS05135
gene id: 980251:MFFC18_RS05135
uniprot id: A0A5B9P4L4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

980251:MFFC18 RS18060
gene id: 980251:MFFC18_RS18060
uniprot id: A0A5B9PNU3
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

980251:MFFC18 RS00500
gene id: 980251:MFFC18_RS00500
uniprot id: A0A5B9P1R8
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

980251:MFFC18 RS07385
gene id: 980251:MFFC18_RS07385
uniprot id: A0A5B9P506
names: Similarity
messages: Belongs to the peptidase M16 family.

980251:MFFC18 RS07240
gene id: 980251:MFFC18_RS07240
uniprot id: A0A5B9P4X7
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980251:MFFC18 RS23740
gene id: 980251:MFFC18_RS23740
uniprot id: A0A5B9PFL9
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family.

980251:MFFC18 RS19285
gene id: 980251:MFFC18_RS19285
uniprot id: A0A5B9PHM2
names: Similarity
messages: Belongs to the Skp family.

980251:MFFC18 RS21595
gene id: 980251:MFFC18_RS21595
uniprot id: A0A5B9PIV9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

980251:MFFC18 RS16340
gene id: 980251:MFFC18_RS16340
uniprot id: A0A5B9PEF4
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS16740
gene id: 980251:MFFC18_RS16740
uniprot id: A0A5B9PA47
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00630
gene id: 980251:MFFC18_RS00630
uniprot id: A0A5B9P553
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.
messages: Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS05865
gene id: 980251:MFFC18_RS05865
uniprot id: A0A5B9P4P9
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.

980251:MFFC18 RS14215
gene id: 980251:MFFC18_RS14215
uniprot id: A0A5B9PA07
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

980251:MFFC18 RS13380
gene id: 980251:MFFC18_RS13380
uniprot id: A0A5B9P9I7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS02720
gene id: 980251:MFFC18_RS02720
uniprot id: A0A5B9P6A8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS17490
gene id: 980251:MFFC18_RS17490
uniprot id: A0A5B9PBW7
names: Function
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.

980251:MFFC18 RS06150
gene id: 980251:MFFC18_RS06150
uniprot id: A0A5B9PA97
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

980251:MFFC18 RS24385
gene id: 980251:MFFC18_RS24385
uniprot id: A0A5B9PKI6
names: Similarity
messages: Belongs to the glycosyltransferase 1 family.

980251:MFFC18 RS24510
gene id: 980251:MFFC18_RS24510
uniprot id: A0A5B9PRV2
names: Similarity
messages: Belongs to the NTE family.

980251:MFFC18 RS00055
gene id: 980251:MFFC18_RS00055
uniprot id: A0A5B9P4V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecA family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.

980251:MFFC18 RS14385
gene id: 980251:MFFC18_RS14385
uniprot id: A0A5B9PCG2
names: Similarity
messages: Belongs to the LacAB/RpiB family.

980251:MFFC18 RS21965
gene id: 980251:MFFC18_RS21965
uniprot id: A0A5B9PJ47
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

980251:MFFC18 RS18465
gene id: 980251:MFFC18_RS18465
uniprot id: A0A5B9PCL8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: Homotrimer.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

980251:MFFC18 RS19705
gene id: 980251:MFFC18_RS19705
uniprot id: A0A5B9PHV0
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS17410
gene id: 980251:MFFC18_RS17410
uniprot id: A0A5B9PGA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS03910
gene id: 980251:MFFC18_RS03910
uniprot id: A0A5B9P710
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

980251:MFFC18 RS14260
gene id: 980251:MFFC18_RS14260
uniprot id: A0A5B9PA60
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

980251:MFFC18 RS13965
gene id: 980251:MFFC18_RS13965
uniprot id: A0A5B9PKA6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS02570
gene id: 980251:MFFC18_RS02570
uniprot id: A0A5B9P7V5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS03365
gene id: 980251:MFFC18_RS03365
uniprot id: A0A5B9P7D3
names: Similarity
messages: Belongs to the UPF0051 (ycf24) family.

980251:MFFC18 RS15160
gene id: 980251:MFFC18_RS15160
uniprot id: A0A5B9PAD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

980251:MFFC18 RS01500
gene id: 980251:MFFC18_RS01500
uniprot id: A0A5B9P793
names: Similarity
messages: Belongs to the UPF0246 family.

980251:MFFC18 RS14745
gene id: 980251:MFFC18_RS14745
uniprot id: A0A5B9PDI9
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

980251:MFFC18 RS22925
gene id: 980251:MFFC18_RS22925
uniprot id: A0A5B9PJL4
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

980251:MFFC18 RS23420
gene id: 980251:MFFC18_RS23420
uniprot id: A0A5B9PIB8
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS23565
gene id: 980251:MFFC18_RS23565
uniprot id: A0A5B9PIE2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS06180
gene id: 980251:MFFC18_RS06180
uniprot id: A0A5B9PEV3
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

980251:MFFC18 RS05370
gene id: 980251:MFFC18_RS05370
uniprot id: A0A5B9P8N1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

980251:MFFC18 RS15090
gene id: 980251:MFFC18_RS15090
uniprot id: A0A5B9PFB5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

980251:MFFC18 RS16825
gene id: 980251:MFFC18_RS16825
uniprot id: A0A5B9PBJ5
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS21200
gene id: 980251:MFFC18_RS21200
uniprot id: A0A5B9PIN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

980251:MFFC18 RS17385
gene id: 980251:MFFC18_RS17385
uniprot id: A0A5B9PAI5
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS10175
gene id: 980251:MFFC18_RS10175
uniprot id: A0A5B9PBD8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS00625
gene id: 980251:MFFC18_RS00625
uniprot id: A0A5B9P1Z5
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

980251:MFFC18 RS23180
gene id: 980251:MFFC18_RS23180
uniprot id: A0A5B9PI63
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS06995
gene id: 980251:MFFC18_RS06995
uniprot id: A0A5B9PFC6
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

980251:MFFC18 RS15990
gene id: 980251:MFFC18_RS15990
uniprot id: A0A5B9PFU1
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

980251:MFFC18 RS04230
gene id: 980251:MFFC18_RS04230
uniprot id: A0A5B9PDC9
names: Similarity
messages: Belongs to the peptidase S8 family.

980251:MFFC18 RS22045
gene id: 980251:MFFC18_RS22045
uniprot id: A0A5B9PE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS09570
gene id: 980251:MFFC18_RS09570
uniprot id: A0A5B9PCC9
names: Function
names: Similarity
messages: Belongs to the RecO family.
messages: Involved in DNA repair and RecF pathway recombination.

980251:MFFC18 RS04325
gene id: 980251:MFFC18_RS04325
uniprot id: A0A5B9P8V3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS03310
gene id: 980251:MFFC18_RS03310
uniprot id: A0A5B9P7B1
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.

980251:MFFC18 RS20410
gene id: 980251:MFFC18_RS20410
uniprot id: A0A5B9PPG7
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

980251:MFFC18 RS00280
gene id: 980251:MFFC18_RS00280
uniprot id: A0A5B9P5G2
names: Similarity
messages: Belongs to the glycosyl hydrolase 57 family.

980251:MFFC18 RS13935
gene id: 980251:MFFC18_RS13935
uniprot id: A0A5B9PD30
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980251:MFFC18 RS16730
gene id: 980251:MFFC18_RS16730
uniprot id: A0A5B9PEN0
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

980251:MFFC18 RS00470
gene id: 980251:MFFC18_RS00470
uniprot id: A0A5B9PAV2
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

980251:MFFC18 RS16335
gene id: 980251:MFFC18_RS16335
uniprot id: A0A5B9PBA7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseA family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

980251:MFFC18 RS00955
gene id: 980251:MFFC18_RS00955
uniprot id: A0A5B9P5Z9
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20B family.
messages: Binds 2 Zn(2+) ions per subunit.

980251:MFFC18 RS04545
gene id: 980251:MFFC18_RS04545
uniprot id: A0A5B9P4D7
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS05125
gene id: 980251:MFFC18_RS05125
uniprot id: A0A5B9P8I5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

980251:MFFC18 RS20445
gene id: 980251:MFFC18_RS20445
uniprot id: A0A5B9PCD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

980251:MFFC18 RS23675
gene id: 980251:MFFC18_RS23675
uniprot id: A0A5B9PHH6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. Biotin synthase family.
messages: Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.
messages: Homodimer.

980251:MFFC18 RS18410
gene id: 980251:MFFC18_RS18410
uniprot id: A0A5B9PP11
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

980251:MFFC18 RS15960
gene id: 980251:MFFC18_RS15960
uniprot id: A0A5B9PEB6
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

980251:MFFC18 RS05215
gene id: 980251:MFFC18_RS05215
uniprot id: A0A5B9P8N6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS00090
gene id: 980251:MFFC18_RS00090
uniprot id: A0A5B9PAQ6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS04820
gene id: 980251:MFFC18_RS04820
uniprot id: A0A5B9PDQ1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

980251:MFFC18 RS03600
gene id: 980251:MFFC18_RS03600
uniprot id: A0A5B9PCT5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS03050
gene id: 980251:MFFC18_RS03050
uniprot id: A0A5B9P6H8
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 zinc ion.
messages: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.
messages: In the C-terminal section; belongs to the HTP reductase family.
messages: In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.

980251:MFFC18 RS00315
gene id: 980251:MFFC18_RS00315
uniprot id: A0A5B9P5M2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS12035
gene id: 980251:MFFC18_RS12035
uniprot id: A0A5B9PJK3
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS00645
gene id: 980251:MFFC18_RS00645
uniprot id: A0A5B9P1U5
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

980251:MFFC18 RS15070
gene id: 980251:MFFC18_RS15070
uniprot id: A0A5B9PEF8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Homodimer or homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS19415
gene id: 980251:MFFC18_RS19415
uniprot id: A0A5B9PG33
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.

980251:MFFC18 RS20885
gene id: 980251:MFFC18_RS20885
uniprot id: A0A5B9PPS6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS17835
gene id: 980251:MFFC18_RS17835
uniprot id: A0A5B9PAX6
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS15305
gene id: 980251:MFFC18_RS15305
uniprot id: A0A5B9PCX2
names: Subcellular Location Annotation
messages: Cytoplasm

980251:MFFC18 RS16385
gene id: 980251:MFFC18_RS16385
uniprot id: A0A5B9PBB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

980251:MFFC18 RS20295
gene id: 980251:MFFC18_RS20295
uniprot id: A0A5B9PDB1
names: Similarity
messages: Belongs to the thioredoxin family.

980251:MFFC18 RS02225
gene id: 980251:MFFC18_RS02225
uniprot id: A0A5B9P277
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980251:MFFC18 RS24870
gene id: 980251:MFFC18_RS24870
uniprot id: A0A5B9PFX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uridine kinase family.
messages: Cytoplasm

980251:MFFC18 RS02270
gene id: 980251:MFFC18_RS02270
uniprot id: A0A5B9P7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

980251:MFFC18 RS00190
gene id: 980251:MFFC18_RS00190
uniprot id: A0A5B9PAS4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.

980251:MFFC18 RS05435
gene id: 980251:MFFC18_RS05435
uniprot id: A0A5B9P7V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Membrane

980251:MFFC18 RS17200
gene id: 980251:MFFC18_RS17200
uniprot id: A0A5B9PMD5
names: Function
names: Similarity
messages: Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.

980251:MFFC18 RS11705
gene id: 980251:MFFC18_RS11705
uniprot id: A0A5B9PBS4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

980251:MFFC18 RS04915
gene id: 980251:MFFC18_RS04915
uniprot id: A0A5B9P8I7
names: Similarity
messages: Belongs to the peptidase S9C family.

980251:MFFC18 RS16885
gene id: 980251:MFFC18_RS16885
uniprot id: A0A5B9PA77
names: Caution
names: Function
names: Similarity
messages: Belongs to the GART family.
messages: Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS14360
gene id: 980251:MFFC18_RS14360
uniprot id: A0A5B9PA84
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS19635
gene id: 980251:MFFC18_RS19635
uniprot id: A0A5B9PBY1
names: Function
names: Similarity
messages: Belongs to the vsr family.
messages: May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.

980251:MFFC18 RS14885
gene id: 980251:MFFC18_RS14885
uniprot id: A0A5B9PAI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

980251:MFFC18 RS14020
gene id: 980251:MFFC18_RS14020
uniprot id: A0A5B9P9X3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980251:MFFC18 RS05055
gene id: 980251:MFFC18_RS05055
uniprot id: A0A5B9P479
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

980251:MFFC18 RS17460
gene id: 980251:MFFC18_RS17460
uniprot id: A0A5B9PGB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

980251:MFFC18 RS06115
gene id: 980251:MFFC18_RS06115
uniprot id: A0A5B9P7E5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

980251:MFFC18 RS16700
gene id: 980251:MFFC18_RS16700
uniprot id: A0A5B9PDS9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD kinase family.
messages: Cytoplasm
messages: Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS03990
gene id: 980251:MFFC18_RS03990
uniprot id: A0A5B9P7S0
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS21810
gene id: 980251:MFFC18_RS21810
uniprot id: A0A5B9PGD6
names: Similarity
messages: Belongs to the Dps family.

980251:MFFC18 RS06095
gene id: 980251:MFFC18_RS06095
uniprot id: A0A5B9P873
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

980251:MFFC18 RS24635
gene id: 980251:MFFC18_RS24635
uniprot id: A0A5B9PKN5
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

980251:MFFC18 RS17065
gene id: 980251:MFFC18_RS17065
uniprot id: A0A5B9PBT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

980251:MFFC18 RS14855
gene id: 980251:MFFC18_RS14855
uniprot id: A0A5B9PA80
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

980251:MFFC18 RS20765
gene id: 980251:MFFC18_RS20765
uniprot id: A0A5B9PCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).

980251:MFFC18 RS09180
gene id: 980251:MFFC18_RS09180
uniprot id: A0A5B9PA00
names: Similarity
messages: Belongs to the fructosamine kinase family.

980251:MFFC18 RS13175
gene id: 980251:MFFC18_RS13175
uniprot id: A0A5B9P8A6
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS19000
gene id: 980251:MFFC18_RS19000
uniprot id: A0A5B9PCU5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980251:MFFC18 RS09360
gene id: 980251:MFFC18_RS09360
uniprot id: A0A5B9PHJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NqrDE/RnfAE family.
messages: Cell membrane
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: Membrane
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980251:MFFC18 RS06120
gene id: 980251:MFFC18_RS06120
uniprot id: A0A5B9P962
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

980251:MFFC18 RS18945
gene id: 980251:MFFC18_RS18945
uniprot id: A0A5B9PCT7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

980251:MFFC18 RS20405
gene id: 980251:MFFC18_RS20405
uniprot id: A0A5B9PGK7
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

980251:MFFC18 RS19735
gene id: 980251:MFFC18_RS19735
uniprot id: A0A5B9PD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

980251:MFFC18 RS00495
gene id: 980251:MFFC18_RS00495
uniprot id: A0A5B9P176
names: Function
names: Similarity
names: Subunit
messages: APS kinase catalyzes the synthesis of activated sulfate.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: Heterodimer composed of CysD, the smaller subunit, and CysN.
messages: In the C-terminal section; belongs to the APS kinase family.
messages: In the N-terminal section; belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
messages: With CysD forms the ATP sulfurylase (ATPS) that catalyzes the adenylation of sulfate producing adenosine 5'-phosphosulfate (APS) and diphosphate, the first enzymatic step in sulfur assimilation pathway. APS synthesis involves the formation of a high-energy phosphoric-sulfuric acid anhydride bond driven by GTP hydrolysis by CysN coupled to ATP hydrolysis by CysD.

980251:MFFC18 RS23300
gene id: 980251:MFFC18_RS23300
uniprot id: A0A5B9PR65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

980251:MFFC18 RS17635
gene id: 980251:MFFC18_RS17635
uniprot id: A0A5B9PAP6
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS05365
gene id: 980251:MFFC18_RS05365
uniprot id: A0A5B9PE16
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

980251:MFFC18 RS20005
gene id: 980251:MFFC18_RS20005
uniprot id: A0A5B9PP30
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

980251:MFFC18 RS20435
gene id: 980251:MFFC18_RS20435
uniprot id: A0A5B9PGN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

980251:MFFC18 RS05760
gene id: 980251:MFFC18_RS05760
uniprot id: A0A5B9P410
names: Similarity
messages: Belongs to the peptidase S1C family.

980251:MFFC18 RS11750
gene id: 980251:MFFC18_RS11750
uniprot id: A0A5B9P8F3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acetokinase family.
messages: Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.
messages: Cytoplasm
messages: Homodimer.
messages: Mg(2+). Can also accept Mn(2+).

980251:MFFC18 RS21875
gene id: 980251:MFFC18_RS21875
uniprot id: A0A5B9PEL1
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

980251:MFFC18 RS22865
gene id: 980251:MFFC18_RS22865
uniprot id: A0A5B9PH17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980251:MFFC18 RS18795
gene id: 980251:MFFC18_RS18795
uniprot id: A0A5B9PH15
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

980251:MFFC18 RS06055
gene id: 980251:MFFC18_RS06055
uniprot id: A0A5B9P4T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

980251:MFFC18 RS21070
gene id: 980251:MFFC18_RS21070
uniprot id: A0A5B9PG08
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M3B family.
messages: Binds 1 zinc ion.
messages: Has oligopeptidase activity and degrades a variety of small bioactive peptides.

980251:MFFC18 RS06125
gene id: 980251:MFFC18_RS06125
uniprot id: A0A5B9PEF9
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

980251:MFFC18 RS19365
gene id: 980251:MFFC18_RS19365
uniprot id: A0A5B9PF58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

980251:MFFC18 RS16370
gene id: 980251:MFFC18_RS16370
uniprot id: A0A5B9PLN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

980251:MFFC18 RS00430
gene id: 980251:MFFC18_RS00430
uniprot id: A0A5B9PAV3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

980251:MFFC18 RS23940
gene id: 980251:MFFC18_RS23940
uniprot id: A0A5B9PEI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

980251:MFFC18 RS02620
gene id: 980251:MFFC18_RS02620
uniprot id: A0A5B9P691
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

980251:MFFC18 RS01900
gene id: 980251:MFFC18_RS01900
uniprot id: A0A5B9P6C8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. PriA subfamily.
messages: Component of the primosome.
messages: Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.

980251:MFFC18 RS01305
gene id: 980251:MFFC18_RS01305
uniprot id: A0A5B9P755
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Cytoplasm
messages: Homodecamer. Pentamer of dimers that assemble into a ring structure.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. Although the primary sequence of this enzyme is similar to those of the 1-Cys Prx6 enzymes, its catalytic properties resemble those of the typical 2-Cys Prxs and C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

980251:MFFC18 RS11995
gene id: 980251:MFFC18_RS11995
uniprot id: A0A5B9P8K4
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family. Type B subfamily.
messages: Part of the 50S ribosomal subunit.

980251:MFFC18 RS19765
gene id: 980251:MFFC18_RS19765
uniprot id: A0A5B9PD73
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

980251:MFFC18 RS16515
gene id: 980251:MFFC18_RS16515
uniprot id: A0A5B9PEM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS20710
gene id: 980251:MFFC18_RS20710
uniprot id: A0A5B9PIE4
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS21080
gene id: 980251:MFFC18_RS21080
uniprot id: A0A5B9PPW6
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS07460
gene id: 980251:MFFC18_RS07460
uniprot id: A0A5B9PB06
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

980251:MFFC18 RS10325
gene id: 980251:MFFC18_RS10325
uniprot id: A0A5B9PA31
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

980251:MFFC18 RS19700
gene id: 980251:MFFC18_RS19700
uniprot id: A0A5B9PNW4
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS01605
gene id: 980251:MFFC18_RS01605
uniprot id: A0A5B9P6D9
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS00255
gene id: 980251:MFFC18_RS00255
uniprot id: A0A5B9P6C6
names: Similarity
messages: Belongs to the FPG family.

980251:MFFC18 RS00830
gene id: 980251:MFFC18_RS00830
uniprot id: A0A5B9P587
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS15265
gene id: 980251:MFFC18_RS15265
uniprot id: A0A5B9PL04
names: Similarity
messages: Belongs to the FlgD family.

980251:MFFC18 RS00720
gene id: 980251:MFFC18_RS00720
uniprot id: A0A5B9PB16
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

980251:MFFC18 RS03455
gene id: 980251:MFFC18_RS03455
uniprot id: A0A5B9P7E1
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05130
gene id: 980251:MFFC18_RS05130
uniprot id: A0A5B9PE51
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

980251:MFFC18 RS02375
gene id: 980251:MFFC18_RS02375
uniprot id: A0A5B9P7S2
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

980251:MFFC18 RS00995
gene id: 980251:MFFC18_RS00995
uniprot id: A0A5B9P212
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Coproporphyrinogen III oxidase subfamily.
messages: Cytoplasm
messages: Involved in coproporphyrin-dependent heme b biosynthesis. Catalyzes the oxidation of coproporphyrinogen III to coproporphyrin III.

980251:MFFC18 RS04055
gene id: 980251:MFFC18_RS04055
uniprot id: A0A5B9PD88
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS14695
gene id: 980251:MFFC18_RS14695
uniprot id: A0A5B9PAF1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

980251:MFFC18 RS17175
gene id: 980251:MFFC18_RS17175
uniprot id: A0A5B9PGM1
names: Similarity
messages: Belongs to the DtxR/MntR family.

980251:MFFC18 RS01890
gene id: 980251:MFFC18_RS01890
uniprot id: A0A5B9P6J5
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS12970
gene id: 980251:MFFC18_RS12970
uniprot id: A0A5B9P9B3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS21755
gene id: 980251:MFFC18_RS21755
uniprot id: A0A5B9PE24
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

980251:MFFC18 RS08500
gene id: 980251:MFFC18_RS08500
uniprot id: A0A5B9PAG1
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS01675
gene id: 980251:MFFC18_RS01675
uniprot id: A0A5B9PBJ7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS19585
gene id: 980251:MFFC18_RS19585
uniprot id: A0A5B9PG78
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS05670
gene id: 980251:MFFC18_RS05670
uniprot id: A0A5B9P706
names: Similarity
messages: Belongs to the UPF0145 family.

980251:MFFC18 RS16690
gene id: 980251:MFFC18_RS16690
uniprot id: A0A5B9PA42
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS23260
gene id: 980251:MFFC18_RS23260
uniprot id: A0A5B9PJT0
names: Similarity
messages: Belongs to the heat shock protein 70 family.

980251:MFFC18 RS19850
gene id: 980251:MFFC18_RS19850
uniprot id: A0A5B9PNZ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

980251:MFFC18 RS06665
gene id: 980251:MFFC18_RS06665
uniprot id: A0A5B9PAL1
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

980251:MFFC18 RS11050
gene id: 980251:MFFC18_RS11050
uniprot id: A0A5B9PC45
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS22020
gene id: 980251:MFFC18_RS22020
uniprot id: A0A5B9PQX3
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS01035
gene id: 980251:MFFC18_RS01035
uniprot id: A0A5B9P6T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
messages: Cytoplasm
messages: Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity.

980251:MFFC18 RS14545
gene id: 980251:MFFC18_RS14545
uniprot id: A0A5B9PE47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial secretin family.
messages: Cell outer membrane

980251:MFFC18 RS22080
gene id: 980251:MFFC18_RS22080
uniprot id: A0A5B9PHH8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS19855
gene id: 980251:MFFC18_RS19855
uniprot id: A0A5B9PHY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

980251:MFFC18 RS23575
gene id: 980251:MFFC18_RS23575
uniprot id: A0A5B9PEA9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS07580
gene id: 980251:MFFC18_RS07580
uniprot id: A0A5B9PFK2
names: Function
messages: Catalyzes the formation of 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P).

980251:MFFC18 RS24500
gene id: 980251:MFFC18_RS24500
uniprot id: A0A5B9PHZ2
names: Similarity
messages: Belongs to the SufE family.

980251:MFFC18 RS13640
gene id: 980251:MFFC18_RS13640
uniprot id: A0A5B9PD65
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00220
gene id: 980251:MFFC18_RS00220
uniprot id: A0A5B9P3Z4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the YjjX NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

980251:MFFC18 RS18730
gene id: 980251:MFFC18_RS18730
uniprot id: A0A5B9PEU0
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS16120
gene id: 980251:MFFC18_RS16120
uniprot id: A0A5B9PDI2
names: Similarity
messages: Belongs to the peptidase M4 family.

980251:MFFC18 RS12755
gene id: 980251:MFFC18_RS12755
uniprot id: A0A5B9PE52
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS08390
gene id: 980251:MFFC18_RS08390
uniprot id: A0A5B9P5P5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCH family.
messages: Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl-H(4)MPT.
messages: Cytoplasm

980251:MFFC18 RS14505
gene id: 980251:MFFC18_RS14505
uniprot id: A0A5B9PLI7
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

980251:MFFC18 RS15505
gene id: 980251:MFFC18_RS15505
uniprot id: A0A5B9PD14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

980251:MFFC18 RS12225
gene id: 980251:MFFC18_RS12225
uniprot id: A0A5B9PB53
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

980251:MFFC18 RS10615
gene id: 980251:MFFC18_RS10615
uniprot id: A0A5B9PBV8
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.

980251:MFFC18 RS20145
gene id: 980251:MFFC18_RS20145
uniprot id: A0A5B9PD77
names: Caution
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS00795
gene id: 980251:MFFC18_RS00795
uniprot id: A0A5B9P1X6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

980251:MFFC18 RS03825
gene id: 980251:MFFC18_RS03825
uniprot id: A0A5B9P3H9
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

980251:MFFC18 RS15935
gene id: 980251:MFFC18_RS15935
uniprot id: A0A5B9PE71
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS02100
gene id: 980251:MFFC18_RS02100
uniprot id: A0A5B9P6G7
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

980251:MFFC18 RS19980
gene id: 980251:MFFC18_RS19980
uniprot id: A0A5B9PI05
names: Function
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

980251:MFFC18 RS07660
gene id: 980251:MFFC18_RS07660
uniprot id: A0A5B9P591
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00550
gene id: 980251:MFFC18_RS00550
uniprot id: A0A5B9P1S9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Membrane

980251:MFFC18 RS13515
gene id: 980251:MFFC18_RS13515
uniprot id: A0A5B9PCW7
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS05990
gene id: 980251:MFFC18_RS05990
uniprot id: A0A5B9P543
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS02005
gene id: 980251:MFFC18_RS02005
uniprot id: A0A5B9PBP4
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS00485
gene id: 980251:MFFC18_RS00485
uniprot id: A0A5B9P532
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS09345
gene id: 980251:MFFC18_RS09345
uniprot id: A0A5B9PAX7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NqrA family.
messages: Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.
messages: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.

980251:MFFC18 RS12350
gene id: 980251:MFFC18_RS12350
uniprot id: A0A5B9PJT2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS04335
gene id: 980251:MFFC18_RS04335
uniprot id: A0A5B9P3S3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.
messages: Cell membrane
messages: Forms a complex with DabB.
messages: Part of an energy-coupled inorganic carbon pump.

980251:MFFC18 RS05065
gene id: 980251:MFFC18_RS05065
uniprot id: A0A5B9P8L2
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS05630
gene id: 980251:MFFC18_RS05630
uniprot id: A0A5B9PE68
names: Function
names: Similarity
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).

980251:MFFC18 RS06250
gene id: 980251:MFFC18_RS06250
uniprot id: A0A5B9PAC0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).
messages: Homodimer.

980251:MFFC18 RS03555
gene id: 980251:MFFC18_RS03555
uniprot id: A0A5B9P7G9
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS14560
gene id: 980251:MFFC18_RS14560
uniprot id: A0A5B9PDE4
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

980251:MFFC18 RS03750
gene id: 980251:MFFC18_RS03750
uniprot id: A0A5B9P7L0
names: Subcellular Location Annotation
messages: Secreted

980251:MFFC18 RS22105
gene id: 980251:MFFC18_RS22105
uniprot id: A0A5B9PHF8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS03380
gene id: 980251:MFFC18_RS03380
uniprot id: A0A5B9P6P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS20835
gene id: 980251:MFFC18_RS20835
uniprot id: A0A5B9PPR2
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

980251:MFFC18 RS15020
gene id: 980251:MFFC18_RS15020
uniprot id: A0A5B9PLZ6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.

980251:MFFC18 RS18215
gene id: 980251:MFFC18_RS18215
uniprot id: A0A5B9PCH5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

980251:MFFC18 RS08260
gene id: 980251:MFFC18_RS08260
uniprot id: A0A5B9PG00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.

980251:MFFC18 RS05995
gene id: 980251:MFFC18_RS05995
uniprot id: A0A5B9P852
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P-Pant transferase superfamily. AcpS family.
messages: Cytoplasm
messages: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.

980251:MFFC18 RS16050
gene id: 980251:MFFC18_RS16050
uniprot id: A0A5B9PB08
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xylose isomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.

980251:MFFC18 RS03960
gene id: 980251:MFFC18_RS03960
uniprot id: A0A5B9P8N4
names: Similarity
messages: Belongs to the bacterial secretin family.

980251:MFFC18 RS17190
gene id: 980251:MFFC18_RS17190
uniprot id: A0A5B9PE27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0014 family.
messages: Membrane

980251:MFFC18 RS14015
gene id: 980251:MFFC18_RS14015
uniprot id: A0A5B9PL85
names: Similarity
messages: Belongs to the GSP E family.

980251:MFFC18 RS15900
gene id: 980251:MFFC18_RS15900
uniprot id: A0A5B9PAX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS12515
gene id: 980251:MFFC18_RS12515
uniprot id: A0A5B9PBH7
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

980251:MFFC18 RS09050
gene id: 980251:MFFC18_RS09050
uniprot id: A0A5B9PC33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980251:MFFC18 RS22180
gene id: 980251:MFFC18_RS22180
uniprot id: A0A5B9PJB5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

980251:MFFC18 RS14255
gene id: 980251:MFFC18_RS14255
uniprot id: A0A5B9PLD6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Cell membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

980251:MFFC18 RS24400
gene id: 980251:MFFC18_RS24400
uniprot id: A0A5B9PHX3
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS18525
gene id: 980251:MFFC18_RS18525
uniprot id: A0A5B9PBB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

980251:MFFC18 RS20780
gene id: 980251:MFFC18_RS20780
uniprot id: A0A5B9PGS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

980251:MFFC18 RS05470
gene id: 980251:MFFC18_RS05470
uniprot id: A0A5B9P8Q1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

980251:MFFC18 RS06970
gene id: 980251:MFFC18_RS06970
uniprot id: A0A5B9P5C8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbsD / FucU family. RbsD subfamily.
messages: Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
messages: Cytoplasm
messages: Homodecamer.

980251:MFFC18 RS22885
gene id: 980251:MFFC18_RS22885
uniprot id: A0A5B9PF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0702 family.
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS15095
gene id: 980251:MFFC18_RS15095
uniprot id: A0A5B9P9B8
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

980251:MFFC18 RS22790
gene id: 980251:MFFC18_RS22790
uniprot id: A0A5B9PF48
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS10875
gene id: 980251:MFFC18_RS10875
uniprot id: A0A5B9P838
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS01910
gene id: 980251:MFFC18_RS01910
uniprot id: A0A5B9P317
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS22860
gene id: 980251:MFFC18_RS22860
uniprot id: A0A5B9PEQ6
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

980251:MFFC18 RS13945
gene id: 980251:MFFC18_RS13945
uniprot id: A0A5B9P8M9
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS22030
gene id: 980251:MFFC18_RS22030
uniprot id: A0A5B9PHH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 'phage' integrase family. XerC subfamily.
messages: Belongs to the 'phage' integrase family. XerD subfamily.
messages: Cytoplasm
messages: Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.
messages: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.

980251:MFFC18 RS23530
gene id: 980251:MFFC18_RS23530
uniprot id: A0A5B9PE99
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS19280
gene id: 980251:MFFC18_RS19280
uniprot id: A0A5B9PNP1
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

980251:MFFC18 RS05635
gene id: 980251:MFFC18_RS05635
uniprot id: A0A5B9P8S8
names: Similarity
messages: Belongs to the asparaginase 1 family.

980251:MFFC18 RS16760
gene id: 980251:MFFC18_RS16760
uniprot id: A0A5B9PLW1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS01795
gene id: 980251:MFFC18_RS01795
uniprot id: A0A5B9PBK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS19155
gene id: 980251:MFFC18_RS19155
uniprot id: A0A5B9PHL3
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.

980251:MFFC18 RS15500
gene id: 980251:MFFC18_RS15500
uniprot id: A0A5B9PAL0
names: Similarity
messages: Belongs to the glycosyl hydrolase 2 family.

980251:MFFC18 RS09145
gene id: 980251:MFFC18_RS09145
uniprot id: A0A5B9PC49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

980251:MFFC18 RS08590
gene id: 980251:MFFC18_RS08590
uniprot id: A0A5B9P928
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

980251:MFFC18 RS17785
gene id: 980251:MFFC18_RS17785
uniprot id: A0A5B9PAW5
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

980251:MFFC18 RS05845
gene id: 980251:MFFC18_RS05845
uniprot id: A0A5B9P508
names: Function
names: Similarity
messages: Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).

980251:MFFC18 RS02040
gene id: 980251:MFFC18_RS02040
uniprot id: A0A5B9P6M6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

980251:MFFC18 RS14930
gene id: 980251:MFFC18_RS14930
uniprot id: A0A5B9PDM2
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

980251:MFFC18 RS15080
gene id: 980251:MFFC18_RS15080
uniprot id: A0A5B9PAN5
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

980251:MFFC18 RS14985
gene id: 980251:MFFC18_RS14985
uniprot id: A0A5B9PF95
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS03895
gene id: 980251:MFFC18_RS03895
uniprot id: A0A5B9P7P7
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

980251:MFFC18 RS09120
gene id: 980251:MFFC18_RS09120
uniprot id: A0A5B9PAU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

980251:MFFC18 RS21025
gene id: 980251:MFFC18_RS21025
uniprot id: A0A5B9PGX2
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS07090
gene id: 980251:MFFC18_RS07090
uniprot id: A0A5B9P9J8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS21585
gene id: 980251:MFFC18_RS21585
uniprot id: A0A5B9PEG0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Forms a complex with TatA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.

980251:MFFC18 RS23150
gene id: 980251:MFFC18_RS23150
uniprot id: A0A5B9PH73
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

980251:MFFC18 RS03125
gene id: 980251:MFFC18_RS03125
uniprot id: A0A5B9P776
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of a guanine in 16S rRNA.

980251:MFFC18 RS06035
gene id: 980251:MFFC18_RS06035
uniprot id: A0A5B9PES1
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

980251:MFFC18 RS23540
gene id: 980251:MFFC18_RS23540
uniprot id: A0A5B9PIH2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

980251:MFFC18 RS18930
gene id: 980251:MFFC18_RS18930
uniprot id: A0A5B9PFU9
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
messages: Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.

980251:MFFC18 RS19815
gene id: 980251:MFFC18_RS19815
uniprot id: A0A5B9PD84
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS19580
gene id: 980251:MFFC18_RS19580
uniprot id: A0A5B9PD42
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

980251:MFFC18 RS04435
gene id: 980251:MFFC18_RS04435
uniprot id: A0A5B9PDE2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS07185
gene id: 980251:MFFC18_RS07185
uniprot id: A0A5B9P8V0
names: Similarity
messages: Belongs to the MYG1 family.

980251:MFFC18 RS21505
gene id: 980251:MFFC18_RS21505
uniprot id: A0A5B9PCX5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

980251:MFFC18 RS17350
gene id: 980251:MFFC18_RS17350
uniprot id: A0A5B9PMG8
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS17270
gene id: 980251:MFFC18_RS17270
uniprot id: A0A5B9PEY9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

980251:MFFC18 RS05105
gene id: 980251:MFFC18_RS05105
uniprot id: A0A5B9P489
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

980251:MFFC18 RS10775
gene id: 980251:MFFC18_RS10775
uniprot id: A0A5B9PAC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

980251:MFFC18 RS06510
gene id: 980251:MFFC18_RS06510
uniprot id: A0A5B9PF25
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.

980251:MFFC18 RS08475
gene id: 980251:MFFC18_RS08475
uniprot id: A0A5B9P9K2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
messages: Belongs to the CsrA/RsmA family.
messages: Cytoplasm
messages: Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.

980251:MFFC18 RS09320
gene id: 980251:MFFC18_RS09320
uniprot id: A0A5B9P737
names: Similarity
messages: Belongs to the UPF0111 family.

980251:MFFC18 RS01620
gene id: 980251:MFFC18_RS01620
uniprot id: A0A5B9PBI8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the radical SAM superfamily. MqnE family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.

980251:MFFC18 RS00835
gene id: 980251:MFFC18_RS00835
uniprot id: A0A5B9P6P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

980251:MFFC18 RS06200
gene id: 980251:MFFC18_RS06200
uniprot id: A0A5B9P485
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

980251:MFFC18 RS23915
gene id: 980251:MFFC18_RS23915
uniprot id: A0A5B9PIP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

980251:MFFC18 RS01245
gene id: 980251:MFFC18_RS01245
uniprot id: A0A5B9PBB4
names: Similarity
messages: Belongs to the universal stress protein A family.

980251:MFFC18 RS12725
gene id: 980251:MFFC18_RS12725
uniprot id: A0A5B9PCP9
names: Similarity
messages: Belongs to the Fur family.

980251:MFFC18 RS04685
gene id: 980251:MFFC18_RS04685
uniprot id: A0A5B9PDW4
names: Similarity
messages: Belongs to the BlaI transcriptional regulatory family.

980251:MFFC18 RS23505
gene id: 980251:MFFC18_RS23505
uniprot id: A0A5B9PJY1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm

980251:MFFC18 RS00100
gene id: 980251:MFFC18_RS00100
uniprot id: A0A5B9P4V8
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.
messages: Synthesizes alpha-1,4-glucan chains using ADP-glucose.

980251:MFFC18 RS06140
gene id: 980251:MFFC18_RS06140
uniprot id: A0A5B9P571
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

980251:MFFC18 RS21980
gene id: 980251:MFFC18_RS21980
uniprot id: A0A5B9PHG2
names: Similarity
messages: Belongs to the fabD family.

980251:MFFC18 RS14470
gene id: 980251:MFFC18_RS14470
uniprot id: A0A5B9PF03
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

980251:MFFC18 RS03795
gene id: 980251:MFFC18_RS03795
uniprot id: A0A5B9P7M1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS09425
gene id: 980251:MFFC18_RS09425
uniprot id: A0A5B9P6D3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
messages: Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
messages: Homotrimer.

980251:MFFC18 RS01510
gene id: 980251:MFFC18_RS01510
uniprot id: A0A5B9P4Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

980251:MFFC18 RS24640
gene id: 980251:MFFC18_RS24640
uniprot id: A0A5B9PEU9
names: Subcellular Location Annotation
messages: Membrane

980251:MFFC18 RS07895
gene id: 980251:MFFC18_RS07895
uniprot id: A0A5B9P987
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.

980251:MFFC18 RS18515
gene id: 980251:MFFC18_RS18515
uniprot id: A0A5B9PFP3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

980251:MFFC18 RS18460
gene id: 980251:MFFC18_RS18460
uniprot id: A0A5B9PP20
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

980251:MFFC18 RS14660
gene id: 980251:MFFC18_RS14660
uniprot id: A0A5B9P917
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

980251:MFFC18 RS06010
gene id: 980251:MFFC18_RS06010
uniprot id: A0A5B9P4S7
names: Similarity
messages: Belongs to the PrpD family.

980251:MFFC18 RS18510
gene id: 980251:MFFC18_RS18510
uniprot id: A0A5B9PCM5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

980251:MFFC18 RS12745
gene id: 980251:MFFC18_RS12745
uniprot id: A0A5B9P905
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

980251:MFFC18 RS07865
gene id: 980251:MFFC18_RS07865
uniprot id: A0A5B9P8E4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

980251:MFFC18 RS11105
gene id: 980251:MFFC18_RS11105
uniprot id: A0A5B9PIQ7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Heptamer of 7 subunits arranged in a ring.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

980251:MFFC18 RS10595
gene id: 980251:MFFC18_RS10595
uniprot id: A0A5B9P7X9
names: Similarity
messages: Belongs to the glutamate synthase family.

980251:MFFC18 RS16590
gene id: 980251:MFFC18_RS16590
uniprot id: A0A5B9PGA4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the diaminopimelate epimerase family.
messages: Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

980251:MFFC18 RS08330
gene id: 980251:MFFC18_RS08330
uniprot id: A0A5B9P9H7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

980251:MFFC18 RS04940
gene id: 980251:MFFC18_RS04940
uniprot id: A0A5B9P7K4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

980251:MFFC18 RS09710
gene id: 980251:MFFC18_RS09710
uniprot id: A0A5B9PAF3
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS16500
gene id: 980251:MFFC18_RS16500
uniprot id: A0A5B9PA14
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

980251:MFFC18 RS13980
gene id: 980251:MFFC18_RS13980
uniprot id: A0A5B9PD38
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

980251:MFFC18 RS06890
gene id: 980251:MFFC18_RS06890
uniprot id: A0A5B9PF23
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

980251:MFFC18 RS00555
gene id: 980251:MFFC18_RS00555
uniprot id: A0A5B9P453
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

980251:MFFC18 RS21470
gene id: 980251:MFFC18_RS21470
uniprot id: A0A5B9PH40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

980251:MFFC18 RS05460
gene id: 980251:MFFC18_RS05460
uniprot id: A0A5B9P8T1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

980251:MFFC18 RS09475
gene id: 980251:MFFC18_RS09475
uniprot id: A0A5B9P6E3
names: Similarity
messages: Belongs to the GSP E family.