93934:ANAPC16
gene id: 93934:ANAPC16
uniprot id: A0A8C2TDT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APC16 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
messages: Cytoplasm
messages: Nucleus
messages: kinetochore

93934:RARRES2
gene id: 93934:RARRES2
uniprot id: A0A8C2T900
names: Subcellular Location Annotation
messages: Secreted

93934:TCEANC
gene id: 93934:TCEANC
uniprot id: A0A8C2U930
names: Subcellular Location Annotation
messages: Nucleus

93934:CSNK1E
gene id: 93934:CSNK1E
uniprot id: A0A8C2YCC1
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PDCL3
gene id: 93934:PDCL3
uniprot id: A0A8C2Y552
names: Similarity
messages: Belongs to the phosducin family.

93934:ENTPD6
gene id: 93934:ENTPD6
uniprot id: A0A8C2SWR9
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:LOC107308805
gene id: 93934:LOC107308805
uniprot id: A0A8C2TEB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

93934:TSFM
gene id: 93934:TSFM
uniprot id: A0A8C2Y6Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Mitochondrion

93934:FOXJ2
gene id: 93934:FOXJ2
uniprot id: A0A8C2TYK0
names: Subcellular Location Annotation
messages: Nucleus

93934:ARF4
gene id: 93934:ARF4
uniprot id: A0A8C2TT87
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

93934:LOC107321483
gene id: 93934:LOC107321483
uniprot id: A0A8C2UC19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

93934:SUPT20H
gene id: 93934:SUPT20H
uniprot id: A0A8C2YGQ3
names: Similarity
messages: Belongs to the SPT20 family.

93934:LOC107307308
gene id: 93934:LOC107307308
uniprot id: A0A8C2UEB2
names: Function
names: Similarity
messages: Belongs to the PET191 family.
messages: Involved in an early step of the mitochondrial complex IV assembly process.

93934:UBE2I
gene id: 93934:UBE2I
uniprot id: A0A8C2TGZ6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:EXOC8
gene id: 93934:EXOC8
uniprot id: A0A8C2Y6B3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: growth cone
messages: perinuclear region

93934:P3H1
gene id: 93934:P3H1
uniprot id: A0A8C2Y8G7
names: Similarity
messages: Belongs to the leprecan family.

93934:KPNA3
gene id: 93934:KPNA3
uniprot id: A0A8C2UBA3
names: Similarity
messages: Belongs to the importin alpha family.

93934:DOP1B
gene id: 93934:DOP1B
uniprot id: A0A8C2T7R3
names: Similarity
messages: Belongs to the dopey family.

93934:PROK2
gene id: 93934:PROK2
uniprot id: A0A8C2U7K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

93934:PABPC1L
gene id: 93934:PABPC1L
uniprot id: A0A8C2UF09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

93934:TSSC4
gene id: 93934:TSSC4
uniprot id: A0A8C2U6Y8
names: Similarity
messages: Belongs to the TSSC4 family.

93934:PITHD1
gene id: 93934:PITHD1
uniprot id: A0A8C2SZI7
names: Similarity
messages: Belongs to the PITHD1 family.

93934:BBOX1
gene id: 93934:BBOX1
uniprot id: A0A8C2TV63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-BBH/TMLD family.
messages: Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
messages: Cytoplasm

93934:ZDHHC5
gene id: 93934:ZDHHC5
uniprot id: A0A8C2U1Z8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:RORB
gene id: 93934:RORB
uniprot id: A0A8C2Y8T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:LOC107320639
gene id: 93934:LOC107320639
uniprot id: A0A8C2T136
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

93934:CNNM2
gene id: 93934:CNNM2
uniprot id: A0A8C2UD87
uniprot id: A0A8C2UF11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

93934:NDUFA12
gene id: 93934:NDUFA12
uniprot id: A0A8C2SXN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA12 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

93934:CDT1
gene id: 93934:CDT1
uniprot id: F1DGG0
names: Similarity
messages: Belongs to the Cdt1 family.

93934:BOK
gene id: 93934:BOK
uniprot id: A0A8C2Y7I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane

93934:MRPL53
gene id: 93934:MRPL53
uniprot id: A0A8C2TIF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

93934:CYLD
gene id: 93934:CYLD
uniprot id: A0A8C2TUK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

93934:LYRM1
gene id: 93934:LYRM1
uniprot id: A0A8C2U936
names: Similarity
messages: Belongs to the complex I LYR family.

93934:CELF3
gene id: 93934:CELF3
uniprot id: A0A8C2SPR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

93934:DNAJC16
gene id: 93934:DNAJC16
uniprot id: A0A8C2Y4T9
names: Subcellular Location Annotation
messages: Membrane

93934:BID
gene id: 93934:BID
uniprot id: A0A8C2U7A2
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2.
messages: Induces caspases and apoptosis. Counters the protective effect of BCL2.
messages: Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:IL7R
gene id: 93934:IL7R
uniprot id: A0A8C2T466
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP).
messages: The IL7 receptor is a heterodimer of IL7R and IL2RG. The TSLP receptor is a heterodimer of CRLF2 and IL7R.

93934:FKBP6
gene id: 93934:FKBP6
uniprot id: A0A8C2SY10
names: Function
names: Similarity
messages: Belongs to the FKBP6 family.
messages: Co-chaperone required during spermatogenesis to repress transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis. May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes.

93934:TWF1
gene id: 93934:TWF1
uniprot id: A0A8C2TRG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

93934:MAP3K8
gene id: 93934:MAP3K8
uniprot id: A0A8C2SWQ9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

93934:MAT1A
gene id: 93934:MAT1A
uniprot id: A0A8C2TLA8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

93934:XKRX
gene id: 93934:XKRX
uniprot id: A0A8C2TXV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:TMEM129
gene id: 93934:TMEM129
uniprot id: A0A8C2T021
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM129 family.
messages: Membrane

93934:GAREM1
gene id: 93934:GAREM1
uniprot id: A0A8C2TCB6
names: Similarity
messages: Belongs to the GAREM family.

93934:PDE6B
gene id: 93934:PDE6B
uniprot id: A0A8C2YBN1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:GPCPD1
gene id: 93934:GPCPD1
uniprot id: A0A8C2T366
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

93934:ANAPC15
gene id: 93934:ANAPC15
uniprot id: A0A8C2SY57
names: Similarity
messages: Belongs to the APC15 family.

93934:TMEM163
gene id: 93934:TMEM163
uniprot id: A0A8C2YH70
uniprot id: A0A8C2YH72
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM163 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: May bind zinc and other divalent cations and recruit them to vesicular organelles.
messages: Membrane
messages: synaptic vesicle membrane

93934:PHYKPL
gene id: 93934:PHYKPL
uniprot id: A0A8C2SYF2
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93934:CCBE1
gene id: 93934:CCBE1
uniprot id: A0A8C2T234
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PGAP2
gene id: 93934:PGAP2
uniprot id: A0A8C2Y7N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP2 family.
messages: Involved in the lipid remodeling steps of GPI-anchor maturation. Required for stable expression of GPI-anchored proteins at the cell surface.
messages: Membrane

93934:TASP1
gene id: 93934:TASP1
uniprot id: A0A8C2SQP5
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

93934:LOC107305842
gene id: 93934:LOC107305842
uniprot id: A0A8C2T3G1
names: Similarity
messages: Belongs to the avidin/streptavidin family.

93934:LOC107309356
gene id: 93934:LOC107309356
uniprot id: A0A8C2SYQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:SGMS2
gene id: 93934:SGMS2
uniprot id: A0A8C2TCT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingomyelin synthase family.
messages: Membrane

93934:GPR15
gene id: 93934:GPR15
uniprot id: A0A8C2U144
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LACC1
gene id: 93934:LACC1
uniprot id: A0A8C2YGL0
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

93934:SNX20
gene id: 93934:SNX20
uniprot id: A0A8C2TS42
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Membrane

93934:CD164
gene id: 93934:CD164
uniprot id: A0A8C2TAS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CD164 family.
messages: Membrane

93934:AMIGO1
gene id: 93934:AMIGO1
uniprot id: A0A8C2TDC1
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

93934:LOC107325543
gene id: 93934:LOC107325543
uniprot id: A0A8C2YAE0
names: Similarity
messages: Belongs to the perilipin family.

93934:RPS16
gene id: 93934:RPS16
uniprot id: A0A8C2SLV5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

93934:ZFP36L1
gene id: 93934:ZFP36L1
uniprot id: A0A8C2U6B3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

93934:SLITRK5
gene id: 93934:SLITRK5
uniprot id: A0A8C2UBW1
names: Similarity
messages: Belongs to the SLITRK family.

93934:CAPZA1
gene id: 93934:CAPZA1
uniprot id: A0A8C2TYI9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

93934:MGMT
gene id: 93934:MGMT
uniprot id: A0A8C2SR08
names: Function
names: Similarity
messages: Belongs to the MGMT family.
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

93934:LOC107318297
gene id: 93934:LOC107318297
uniprot id: A0A8C2YEK8
names: Subcellular Location Annotation
messages: Nucleus

93934:PRORP
gene id: 93934:PRORP
uniprot id: A0A8C2U4F8
names: Similarity
messages: Belongs to the PPR family. P subfamily.

93934:EFNB1
gene id: 93934:EFNB1
uniprot id: A0A8C2SRI8
uniprot id: A0A8C2Y5V5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:PTX3
gene id: 93934:PTX3
uniprot id: A0A8C2U6T8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:GHSR
gene id: 93934:GHSR
uniprot id: C7G187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK-0677, adenosine).

93934:MTG2
gene id: 93934:MTG2
uniprot id: A0A8C2Y637
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

93934:STAR
gene id: 93934:STAR
uniprot id: A0A8C2TYW1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: May interact with TSPO.
messages: Mitochondrion
messages: Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone.

93934:ADRA2C
gene id: 93934:ADRA2C
uniprot id: A0A8C2U8A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:DAZL
gene id: 93934:DAZL
uniprot id: A0A8C2TQD2
names: Subcellular Location Annotation
messages: Cytoplasm

93934:DCLK1
gene id: 93934:DCLK1
uniprot id: A0A8C2UBN0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

93934:GJB1
gene id: 93934:GJB1
uniprot id: A0A8C2TNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Beta-type (group I) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:CACYBP
gene id: 93934:CACYBP
uniprot id: A0A8C2UHW5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in calcium-dependent ubiquitination and subsequent proteasomal degradation of target proteins. Probably serves as a molecular bridge in ubiquitin E3 complexes. Participates in the ubiquitin-mediated degradation of beta-catenin (CTNNB1).
messages: Nucleus

93934:TCF7L2
gene id: 93934:TCF7L2
uniprot id: A0A8C2UA85
uniprot id: A0A8C2UC71
uniprot id: A0A8C2UDE8
uniprot id: A0A8C2UFD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

93934:GAL
gene id: 93934:GAL
uniprot id: Q9W6M9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the galanin family.
messages: Endocrine hormone of the central and peripheral nervous systems that binds and activates the G protein-coupled receptors GALR1, GALR2, and GALR3. This small neuropeptide may regulate diverse physiologic functions including contraction of smooth muscle of the gastrointestinal and genitourinary tract, growth hormone and insulin release and adrenal secretion.
messages: Secreted

93934:LOC107325299
gene id: 93934:LOC107325299
uniprot id: A0A8C2T079
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

93934:GREB1
gene id: 93934:GREB1
uniprot id: A0A8C2YAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GREB1 family.
messages: Membrane

93934:BTG1
gene id: 93934:BTG1
uniprot id: A0A8C2Y6Z8
names: Function
names: Similarity
messages: Anti-proliferative protein.
messages: Belongs to the BTG family.

93934:DPP4
gene id: 93934:DPP4
uniprot id: A0A8C2YD34
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase S9B family. DPPIV subfamily.
messages: Cell junction
messages: Cell membrane
messages: Membrane raft
messages: invadopodium membrane
messages: lamellipodium membrane

93934:ZNF711
gene id: 93934:ZNF711
uniprot id: A0A8C2TY53
uniprot id: A0A8C2TY59
names: Subcellular Location Annotation
messages: Nucleus

93934:NCAPD3
gene id: 93934:NCAPD3
uniprot id: A0A8C2T4N6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the condensin-2 complex.
messages: Nucleus
messages: Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.

93934:STT3B
gene id: 93934:STT3B
uniprot id: A0A8C2YBZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

93934:CNIH3
gene id: 93934:CNIH3
uniprot id: A0A8C2T283
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

93934:SAMM50
gene id: 93934:SAMM50
uniprot id: A0A8C2TWA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAM50/omp85 family.
messages: Mitochondrion outer membrane

93934:OSBP
gene id: 93934:OSBP
uniprot id: A0A8C2TR64
names: Similarity
messages: Belongs to the OSBP family.

93934:PGR
gene id: 93934:PGR
uniprot id: A0A8C2SXV6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Cytoplasm
messages: Nucleus
messages: Steroid hormone receptor involved in the regulation of eukaryotic gene expression which affects cellular proliferation and differentiation in target tissues.

93934:CUL3
gene id: 93934:CUL3
uniprot id: A0A8C2Y7J0
names: Similarity
messages: Belongs to the cullin family.

93934:TERT
gene id: 93934:TERT
uniprot id: Q0PVX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

93934:EBAG9
gene id: 93934:EBAG9
uniprot id: A0A8C2T0S8
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

93934:IGFBP3
gene id: 93934:IGFBP3
uniprot id: A0A8C2U9B4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:LOC107309830
gene id: 93934:LOC107309830
uniprot id: A0A8C2T0U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

93934:CDX1
gene id: 93934:CDX1
uniprot id: A0A8C2SZ70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

93934:PPP6R2
gene id: 93934:PPP6R2
uniprot id: A0A8C2SKP4
uniprot id: A0A8C2Y4X9
names: Similarity
messages: Belongs to the SAPS family.

93934:MINDY2
gene id: 93934:MINDY2
uniprot id: A0A8C2TPN1
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM63 subfamily.
messages: Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins. Has exodeubiquitinase activity and has a preference for long polyubiquitin chains. May play a regulatory role at the level of protein turnover.

93934:ACLY
gene id: 93934:ACLY
uniprot id: A0A8C2T043
uniprot id: A0A8C2T0W6
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis.
messages: Homotetramer.
messages: In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family.
messages: In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family.

93934:LOC107315236
gene id: 93934:LOC107315236
uniprot id: A0A8C2ST59
names: Similarity
messages: Belongs to the serpin family.

93934:LOC107323903
gene id: 93934:LOC107323903
uniprot id: A0A8C2T8V3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

93934:LOC107320485
gene id: 93934:LOC107320485
uniprot id: A0A8C2U3G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine gamma family.
messages: Secreted

93934:CFAP52
gene id: 93934:CFAP52
uniprot id: A0A8C2UDV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP52 family.
messages: Cytoplasm
messages: flagellum

93934:LOC107323378
gene id: 93934:LOC107323378
uniprot id: A0A8C2Y838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the natriuretic peptide family.
messages: Secreted

93934:LOC107308667
gene id: 93934:LOC107308667
uniprot id: A0A8C2TDZ0
uniprot id: A0A8C2TFU2
uniprot id: A0A8C2TIY5
names: Subcellular Location Annotation
messages: Membrane

93934:SFRP5
gene id: 93934:SFRP5
uniprot id: A0A8C2UC79
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:TBX21
gene id: 93934:TBX21
uniprot id: A0A8C2U7D1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:NTNG1
gene id: 93934:NTNG1
uniprot id: A0A8C2UIS4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CPM
gene id: 93934:CPM
uniprot id: A0A8C2TW16
names: Similarity
messages: Belongs to the peptidase M14 family.

93934:MYO3A
gene id: 93934:MYO3A
uniprot id: A0A8C2SX07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: In the C-terminal section; belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: cytoskeleton

93934:GRIN3A
gene id: 93934:GRIN3A
uniprot id: A0A8C2SPA9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:GCK
gene id: 93934:GCK
uniprot id: A0A8C2TKY5
names: Similarity
messages: Belongs to the hexokinase family.

93934:MCM6
gene id: 93934:MCM6
uniprot id: A0A8C2YH75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

93934:LOC107323918
gene id: 93934:LOC107323918
uniprot id: A0A8C2T8A1
uniprot id: A0A8C2TAK9
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

93934:MYOG
gene id: 93934:MYOG
uniprot id: A0A8C2T9N4
names: Subcellular Location Annotation
messages: Nucleus

93934:ASCC3
gene id: 93934:ASCC3
uniprot id: A0A8C2TB06
names: Similarity
messages: Belongs to the helicase family.

93934:LOC107309427
gene id: 93934:LOC107309427
uniprot id: A0A8C2TRD5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:MAN1A1
gene id: 93934:MAN1A1
uniprot id: A0A8C2T9N9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

93934:LOC107314039
gene id: 93934:LOC107314039
uniprot id: A0A8C2Y6X0
names: Similarity
messages: Belongs to the SLBP family.

93934:LCORL
gene id: 93934:LCORL
uniprot id: A0A8C2YFQ2
names: Subcellular Location Annotation
messages: Nucleus

93934:TMEM255A
gene id: 93934:TMEM255A
uniprot id: A0A8C2YG08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM255 family.
messages: Membrane

93934:SCMH1
gene id: 93934:SCMH1
uniprot id: A0A8C2TUZ7
uniprot id: A0A8C2TXE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCM family.
messages: Nucleus

93934:CNOT9
gene id: 93934:CNOT9
uniprot id: A0A8C2TLX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT9 family.
messages: P-body

93934:LOC107321367
gene id: 93934:LOC107321367
uniprot id: A0A8C2YCC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:PIGB
gene id: 93934:PIGB
uniprot id: A0A8C2U2C0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

93934:PSMA3
gene id: 93934:PSMA3
uniprot id: A0A8C2T0X2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

93934:SEPHS1
gene id: 93934:SEPHS1
uniprot id: A0A8C2SXH9
names: Function
messages: Synthesizes selenophosphate from selenide and ATP.

93934:PDCL2
gene id: 93934:PDCL2
uniprot id: A0A8C2THE2
names: Similarity
messages: Belongs to the phosducin family.

93934:ATP7B
gene id: 93934:ATP7B
uniprot id: A0A8C2UCJ1
uniprot id: A0A8C2UEB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

93934:EMC7
gene id: 93934:EMC7
uniprot id: A0A8C2TYC5
names: Similarity
names: Subunit
messages: Belongs to the EMC7 family.
messages: Component of the ER membrane protein complex (EMC).

93934:OSTC
gene id: 93934:OSTC
uniprot id: A0A8C2Y9V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OSTC family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Membrane
messages: Specific component of the STT3A-containing form of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

93934:EPHA4
gene id: 93934:EPHA4
uniprot id: A0A8C2T0M4
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome
messages: Membrane

93934:LOC107312635
gene id: 93934:LOC107312635
uniprot id: A0A8C2T7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:ADAMTS3
gene id: 93934:ADAMTS3
uniprot id: A0A8C2SRI9
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:PEAR1
gene id: 93934:PEAR1
uniprot id: A0A8C2TSQ9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:RHAG
gene id: 93934:RHAG
uniprot id: A0A8C2ST79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

93934:SATB1
gene id: 93934:SATB1
uniprot id: A0A8C2TMT0
uniprot id: A0A8C2YBY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

93934:SUSD2
gene id: 93934:SUSD2
uniprot id: A0A8C2T9M6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:RHCG
gene id: 93934:RHCG
uniprot id: A0A8C2UDD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

93934:PPP1R2
gene id: 93934:PPP1R2
uniprot id: A0A8C2TMH3
names: Similarity
messages: Belongs to the protein phosphatase inhibitor 2 family.

93934:LOC107311979
gene id: 93934:LOC107311979
uniprot id: A0A8C2SYG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP206 family.
messages: cilium axoneme
messages: cilium basal body

93934:CRYZ
gene id: 93934:CRYZ
uniprot id: A0A8C2YD89
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

93934:NEK3
gene id: 93934:NEK3
uniprot id: A0A8C2U935
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:GRIA3
gene id: 93934:GRIA3
uniprot id: A0A8C2U5Z7
uniprot id: A0A8C2UAN6
uniprot id: A0A8C2UB18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:ING3
gene id: 93934:ING3
uniprot id: A0A8C2TP10
uniprot id: A0A8C2YBP1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

93934:HNRNPAB
gene id: 93934:HNRNPAB
uniprot id: A0A8C2SXV9
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:MFF
gene id: 93934:MFF
uniprot id: A0A8C2T9C7
uniprot id: A0A8C2Y8Y8
uniprot id: A0A8C2Y954
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tango11 family.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.

93934:YDJC
gene id: 93934:YDJC
uniprot id: A0A8C2U6D0
names: Function
names: Similarity
messages: Belongs to the YdjC deacetylase family.
messages: Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides.

93934:USP22
gene id: 93934:USP22
uniprot id: A0A8C2SNE2
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:WAPL
gene id: 93934:WAPL
uniprot id: A0A8C2TJK0
uniprot id: A0A8C2TK25
names: Similarity
messages: Belongs to the WAPL family.

93934:MYH10
gene id: 93934:MYH10
uniprot id: A0A8C2UBV9
uniprot id: A0A8C2UE53
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:VAC14
gene id: 93934:VAC14
uniprot id: A0A8C2T6S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VAC14 family.
messages: Endosome membrane
messages: Microsome membrane

93934:CMPK1
gene id: 93934:CMPK1
uniprot id: A0A8C2TEH2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

93934:PHPT1
gene id: 93934:PHPT1
uniprot id: A0A8C2TWT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the janus family.
messages: Cytoplasm
messages: Exhibits phosphohistidine phosphatase activity.
messages: Monomer.

93934:PIK3C2G
gene id: 93934:PIK3C2G
uniprot id: A0A8C2Y633
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

93934:IL21
gene id: 93934:IL21
uniprot id: A0A8C2SV17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

93934:PLA2G10
gene id: 93934:PLA2G10
uniprot id: A0A8C2TTE8
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

93934:LOC107320563
gene id: 93934:LOC107320563
uniprot id: A0A8C2TVG5
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:BRPF1
gene id: 93934:BRPF1
uniprot id: A0A8C2U2Y9
names: Subcellular Location Annotation
messages: Nucleus

93934:ATP5ME
gene id: 93934:ATP5ME
uniprot id: A0A8C2YBI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

93934:PHETA2
gene id: 93934:PHETA2
uniprot id: A0A8C2TBX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sesquipedalian family.
messages: Early endosome
messages: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
messages: Recycling endosome
messages: clathrin-coated vesicle
messages: trans-Golgi network

93934:NFIL3
gene id: 93934:NFIL3
uniprot id: A0A8C2TDF9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. NFIL3 subfamily.
messages: May act as a transcriptional regulator of a number of proteins of the circadian clock.
messages: Nucleus

93934:NDUFA1
gene id: 93934:NDUFA1
uniprot id: A0A8C2U7T6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA1 subunit family.
messages: Mitochondrion inner membrane

93934:IHH
gene id: 93934:IHH
uniprot id: A0A8C2TPK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: Secreted
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

93934:SYN3
gene id: 93934:SYN3
uniprot id: A0A8C2U3R7
names: Similarity
messages: Belongs to the synapsin family.

93934:BICC1
gene id: 93934:BICC1
uniprot id: A0A8C2TJH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BicC family.
messages: Cytoplasm

93934:F13A1
gene id: 93934:F13A1
uniprot id: A0A8C2U120
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

93934:LOC107306428
gene id: 93934:LOC107306428
uniprot id: A0A8C2YBI0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIKI family.
messages: Cell membrane
messages: Divalent metal cations. Mn(2+) or Co(2+).
messages: Membrane
messages: Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation.

93934:FSCN2
gene id: 93934:FSCN2
uniprot id: A0A8C2UGA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

93934:EPHB2
gene id: 93934:EPHB2
uniprot id: A0A8C2Y847
names: Subcellular Location Annotation
messages: Membrane

93934:POMGNT2
gene id: 93934:POMGNT2
uniprot id: A0A8C2TR90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 61 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TRMU
gene id: 93934:TRMU
uniprot id: A0A8C2TBL0
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

93934:LOC107323920
gene id: 93934:LOC107323920
uniprot id: A0A8C2YEC7
names: Subcellular Location Annotation
messages: Nucleus

93934:PSMB2
gene id: 93934:PSMB2
uniprot id: A0A8C2U033
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

93934:CPSF2
gene id: 93934:CPSF2
uniprot id: A0A8C2SNK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

93934:LZIC
gene id: 93934:LZIC
uniprot id: A0A8C2TNT6
names: Similarity
messages: Belongs to the CTNNBIP1 family.

93934:MVK
gene id: 93934:MVK
uniprot id: A0A8C2Y937
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Catalyzes the phosphorylation of mevalonate to mevalonate 5-phosphate, a key step in isoprenoid and cholesterol biosynthesis.
messages: Cytoplasm

93934:LOC107313500
gene id: 93934:LOC107313500
uniprot id: A0A8C2TBK6
names: Similarity
messages: Belongs to the globin family.

93934:LRRFIP2
gene id: 93934:LRRFIP2
uniprot id: A0A8C2T1H7
uniprot id: A0A8C2T1X9
uniprot id: A0A8C2T1Y8
uniprot id: A0A8C2T1Z9
uniprot id: A0A8C2T217
uniprot id: A0A8C2T345
uniprot id: A0A8C2T6H1
names: Similarity
messages: Belongs to the LRRFIP family.

93934:HSPA8
gene id: 93934:HSPA8
uniprot id: A0PA16
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93934:APLP2
gene id: 93934:APLP2
uniprot id: A0A8C2T2M5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TIMM44
gene id: 93934:TIMM44
uniprot id: A0A8C2T2G2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

93934:PIK3R1
gene id: 93934:PIK3R1
uniprot id: A0A8C2T671
uniprot id: A0A8C2T8L8
uniprot id: A0A8C2Y8X9
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

93934:MCM3
gene id: 93934:MCM3
uniprot id: A0A8C2SRP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

93934:RIPOR3
gene id: 93934:RIPOR3
uniprot id: A0A8C2T462
names: Similarity
messages: Belongs to the RIPOR family.

93934:KEF80 p09
gene id: 93934:KEF80_p09
uniprot id: A0A1D9CQQ8
uniprot id: P50682
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase protein 8 family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane (By similarity).
messages: Mitochondrion membrane

93934:MSTN
gene id: 93934:MSTN
uniprot id: A0A8C2TSM8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts specifically as a negative regulator of skeletal muscle growth.
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

93934:UBE2A
gene id: 93934:UBE2A
uniprot id: A0A8C2U7L0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:SNCB
gene id: 93934:SNCB
uniprot id: A0A8C2TJA8
names: Similarity
messages: Belongs to the synuclein family.

93934:NPW
gene id: 93934:NPW
uniprot id: A0A8C2T261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropeptide B/W family.
messages: Secreted

93934:ZC3H12A
gene id: 93934:ZC3H12A
uniprot id: A0A8C2TZ29
names: Similarity
messages: Belongs to the ZC3H12 family.

93934:ATPSCKMT
gene id: 93934:ATPSCKMT
uniprot id: A0A8C2TW43
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
messages: Mitochondrion membrane

93934:LOC107322167
gene id: 93934:LOC107322167
uniprot id: A0A8C2Y6B6
names: Similarity
messages: Belongs to the CD200R family.

93934:LOC107313989
gene id: 93934:LOC107313989
uniprot id: A0A8C2YCJ0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CLDN11
gene id: 93934:CLDN11
uniprot id: A0A8C2U830
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:C5H11orf58
gene id: 93934:C5H11orf58
uniprot id: Q90368
names: Similarity
names: Tissue Specificity
messages: Belongs to the SMAP family.
messages: Expressed in otocyst.

93934:UBA3
gene id: 93934:UBA3
uniprot id: A0A8C2U8U7
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

93934:CCNF
gene id: 93934:CCNF
uniprot id: A0A8C2U9D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family.
messages: centriole
messages: perinuclear region

93934:NPEPL1
gene id: 93934:NPEPL1
uniprot id: A0A8C2T8R1
names: Similarity
messages: Belongs to the peptidase M17 family.

93934:NSFL1C
gene id: 93934:NSFL1C
uniprot id: A0A8C2T0W7
names: Subcellular Location Annotation
messages: Golgi stack

93934:LOC107309649
gene id: 93934:LOC107309649
uniprot id: A0A8C2U4Q1
names: Similarity
messages: Belongs to the TMEM14 family.

93934:VPS26C
gene id: 93934:VPS26C
uniprot id: A0A8C2T5Y1
names: Similarity
messages: Belongs to the VPS26 family.

93934:FOXF2
gene id: 93934:FOXF2
uniprot id: A0A8C2TVA3
names: Subcellular Location Annotation
messages: Nucleus

93934:IFRD1
gene id: 93934:IFRD1
uniprot id: A0A8C2TNE8
names: Similarity
messages: Belongs to the IFRD family.

93934:ATF4
gene id: 93934:ATF4
uniprot id: A0A8C2TNA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

93934:CACNB1
gene id: 93934:CACNB1
uniprot id: A0A8C2SQ85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: Membrane
messages: sarcolemma

93934:GPR68
gene id: 93934:GPR68
uniprot id: A0A8C2SKZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:SLC35B2
gene id: 93934:SLC35B2
uniprot id: C7G499
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

93934:RALB
gene id: 93934:RALB
uniprot id: A0A8C2YC30
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

93934:RSPO3
gene id: 93934:RSPO3
uniprot id: A0A8C2T9Y7
names: Similarity
messages: Belongs to the R-spondin family.

93934:TMEM43
gene id: 93934:TMEM43
uniprot id: A0A8C2TZ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM43 family.
messages: Membrane

93934:ATAD1
gene id: 93934:ATAD1
uniprot id: A0A8C2TLL8
names: Similarity
messages: Belongs to the AAA ATPase family.

93934:UBE2L3
gene id: 93934:UBE2L3
uniprot id: A0A8C2U607
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:GGT5
gene id: 93934:GGT5
uniprot id: A0A8C2TAX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

93934:TOLLIP
gene id: 93934:TOLLIP
uniprot id: A0A8C2U4R7
uniprot id: A0A8C2U725
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tollip family.
messages: Cytoplasm

93934:PARVA
gene id: 93934:PARVA
uniprot id: A0A8C2SM44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parvin family.
messages: cytoskeleton

93934:SLC25A3
gene id: 93934:SLC25A3
uniprot id: A0A8C2SY07
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Interacts with PPIF; the interaction is impaired by CsA.
messages: Membrane
messages: Mitochondrion inner membrane

93934:KCNJ1
gene id: 93934:KCNJ1
uniprot id: A0A8C2Y7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

93934:CUL2
gene id: 93934:CUL2
uniprot id: A0A8C2SUH0
uniprot id: A0A8C2SWJ1
names: Similarity
messages: Belongs to the cullin family.

93934:SPRY1
gene id: 93934:SPRY1
uniprot id: A0A8C2SRT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sprouty family.
messages: Cytoplasm
messages: Membrane

93934:PPP1CC
gene id: 93934:PPP1CC
uniprot id: A0A8C2Y4K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-1 subfamily.
messages: Cleavage furrow
messages: Cytoplasm
messages: Midbody

93934:LOC107307715
gene id: 93934:LOC107307715
uniprot id: A0A8C2U5I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

93934:LOC107310337
gene id: 93934:LOC107310337
uniprot id: A0A8C2SKB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

93934:GLI1
gene id: 93934:GLI1
uniprot id: A0A8C2SW90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

93934:PRDM1
gene id: 93934:PRDM1
uniprot id: A0A8C2TAQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Cytoplasm
messages: Interacts with PRMT5. Interacts with FBXO10. Interacts with FBXO11.
messages: Nucleus
messages: Transcription factor that mediates a transcriptional program in various innate and adaptive immune tissue-resident lymphocyte T cell types such as tissue-resident memory T (Trm), natural killer (trNK) and natural killer T (NKT) cells and negatively regulates gene expression of proteins that promote the egress of tissue-resident T-cell populations from non-lymphoid organs. Plays a role in the development, retention and long-term establishment of adaptive and innate tissue-resident lymphocyte T cell types in non-lymphoid organs, such as the skin and gut, but also in other nonbarrier tissues like liver and kidney, and therefore may provide immediate immunological protection against reactivating infections or viral reinfection. Binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells. Associates with the transcriptional repressor ZNF683 to chromatin at gene promoter regions.

93934:DHDDS
gene id: 93934:DHDDS
uniprot id: A0A8C2TXW2
names: Similarity
messages: Belongs to the UPP synthase family.

93934:EIF4A2
gene id: 93934:EIF4A2
uniprot id: A0A8C2TSM9
names: Similarity
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

93934:GNPDA2
gene id: 93934:GNPDA2
uniprot id: A0A8C2U284
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

93934:TM6SF1
gene id: 93934:TM6SF1
uniprot id: A0A8C2UE55
names: Subcellular Location Annotation
messages: Membrane

93934:SGCD
gene id: 93934:SGCD
uniprot id: A0A8C2T3Y1
uniprot id: A0A8C2Y8K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

93934:ISL1
gene id: 93934:ISL1
uniprot id: A0A8C2TKI5
names: Subcellular Location Annotation
messages: Nucleus

93934:GALNT18
gene id: 93934:GALNT18
uniprot id: A0A8C2SPA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:EXOC5
gene id: 93934:EXOC5
uniprot id: A0A8C2T0K6
uniprot id: A0A8C2T3E8
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

93934:SLC17A9
gene id: 93934:SLC17A9
uniprot id: A0A8C2SUZ3
names: Subcellular Location Annotation
messages: Membrane

93934:ACSL1
gene id: 93934:ACSL1
uniprot id: A0A8C2TGI8
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoAs for both synthesis of cellular lipids, and degradation via beta-oxidation.

93934:KIT
gene id: 93934:KIT
uniprot id: A0A8C2TEJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

93934:SNX19
gene id: 93934:SNX19
uniprot id: A0A8C2T3W1
names: Similarity
messages: Belongs to the sorting nexin family.

93934:FOXD3
gene id: 93934:FOXD3
uniprot id: A0A8C2TV29
names: Subcellular Location Annotation
messages: Nucleus

93934:RALA
gene id: 93934:RALA
uniprot id: A0A8C2T0U3
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family.

93934:XKR4
gene id: 93934:XKR4
uniprot id: A0A8C2TGF0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:DDX3X
gene id: 93934:DDX3X
uniprot id: A0A8C2TMZ2
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:NUCB2
gene id: 93934:NUCB2
uniprot id: A0A8C2T2B9
names: Similarity
messages: Belongs to the nucleobindin family.

93934:LOC107313657
gene id: 93934:LOC107313657
uniprot id: A0A8C2T2N7
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

93934:EPC2
gene id: 93934:EPC2
uniprot id: A0A8C2YHE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Nucleus

93934:LOC107325818
gene id: 93934:LOC107325818
uniprot id: A0A8C2SWN1
names: Similarity
messages: Belongs to the intermediate filament family.

93934:IRX4
gene id: 93934:IRX4
uniprot id: A0A8C2TTI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

93934:UTP15
gene id: 93934:UTP15
uniprot id: A0A8C2SR43
names: Subcellular Location Annotation
messages: nucleolus

93934:ANO6
gene id: 93934:ANO6
uniprot id: A0A8C2TNK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

93934:KCNE3
gene id: 93934:KCNE3
uniprot id: A0A8C2T3L5
names: Similarity
messages: Belongs to the potassium channel KCNE family.

93934:MID1IP1
gene id: 93934:MID1IP1
uniprot id: A0A8C2U1F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

93934:LOC107322341
gene id: 93934:LOC107322341
uniprot id: A0A8C2SL39
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Interacts with NCDN.
messages: Membrane

93934:CLDN12
gene id: 93934:CLDN12
uniprot id: A0A8C2T3B7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Membrane
messages: tight junction

93934:ACAA2
gene id: 93934:ACAA2
uniprot id: A0A8C2SX04
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93934:SRSF2
gene id: 93934:SRSF2
uniprot id: A0A8C2UEI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the splicing factor SR family.
messages: Nucleus

93934:LOC107311190
gene id: 93934:LOC107311190
uniprot id: A0A8C2T8D3
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

93934:ATP13A4
gene id: 93934:ATP13A4
uniprot id: A0A8C2YCJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

93934:LRWD1
gene id: 93934:LRWD1
uniprot id: A0A8C2TE52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRWD1 family.
messages: centrosome
messages: kinetochore
messages: telomere

93934:MARCO
gene id: 93934:MARCO
uniprot id: A0A8C2YHK1
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:APH1A
gene id: 93934:APH1A
uniprot id: A0A8C2TYS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

93934:MRPL3
gene id: 93934:MRPL3
uniprot id: A0A8C2SP61
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

93934:UBIAD1
gene id: 93934:UBIAD1
uniprot id: A0A8C2U1M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Membrane

93934:LOC107306797
gene id: 93934:LOC107306797
uniprot id: A0A8C2TSJ0
uniprot id: A0A8C2YCD3
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

93934:PRUNE1
gene id: 93934:PRUNE1
uniprot id: A0A8C2TWP9
names: Similarity
messages: Belongs to the PPase class C family. Prune subfamily.

93934:GJA4
gene id: 93934:GJA4
uniprot id: A0A8C2U2B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:SURF6
gene id: 93934:SURF6
uniprot id: A0A8C2T4B8
names: Similarity
messages: Belongs to the SURF6 family.

93934:KIF2A
gene id: 93934:KIF2A
uniprot id: A0A8C2SP02
uniprot id: A0A8C2ST46
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:SLC7A2
gene id: 93934:SLC7A2
uniprot id: A0A8C2TEI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

93934:TLCD1
gene id: 93934:TLCD1
uniprot id: A0A8C2TMC9
names: Subcellular Location Annotation
messages: Membrane

93934:GPR12
gene id: 93934:GPR12
uniprot id: A0A8C2SLY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:NDEL1
gene id: 93934:NDEL1
uniprot id: A0A8C2UHB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

93934:LOC107315759
gene id: 93934:LOC107315759
uniprot id: A0A8C2T2F9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

93934:ATOH7
gene id: 93934:ATOH7
uniprot id: A0A8C2SP70
names: Subcellular Location Annotation
messages: Nucleus
messages: Perikaryon
messages: axon

93934:TIMM21
gene id: 93934:TIMM21
uniprot id: A0A8C2T992
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

93934:PARP11
gene id: 93934:PARP11
uniprot id: A0A8C2TYM0
uniprot id: A0A8C2TYP0
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:XIRP1
gene id: 93934:XIRP1
uniprot id: A0A8C2TFC7
names: Domain
names: Similarity
messages: Belongs to the Xin family.
messages: Xin repeats bind F-actin.

93934:SLC26A4
gene id: 93934:SLC26A4
uniprot id: A0A8C2Y836
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane
messages: Sodium-independent transporter of chloride and iodide.

93934:FAM91A1
gene id: 93934:FAM91A1
uniprot id: A0A8C2T255
names: Similarity
messages: Belongs to the FAM91 family.

93934:PBX3
gene id: 93934:PBX3
uniprot id: A0A8C2TIC9
uniprot id: A0A8C2YAU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

93934:PRMT7
gene id: 93934:PRMT7
uniprot id: A0A8C2TNI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. PRMT7 subfamily.
messages: Nucleus
messages: cytosol

93934:TCF25
gene id: 93934:TCF25
uniprot id: A0A8C2TTM7
names: Similarity
messages: Belongs to the TCF25 family.

93934:VEZT
gene id: 93934:VEZT
uniprot id: A0A8C2SX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vezatin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction

93934:HSD17B4
gene id: 93934:HSD17B4
uniprot id: A0A8C2SXT9
names: Subcellular Location Annotation
messages: Peroxisome

93934:PRICKLE1
gene id: 93934:PRICKLE1
uniprot id: A0A8C2TRJ6
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

93934:DYNLT3
gene id: 93934:DYNLT3
uniprot id: A0A8C2YEQ1
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

93934:FOXI3
gene id: 93934:FOXI3
uniprot id: A0A8C2T4A2
names: Subcellular Location Annotation
messages: Nucleus

93934:ENTPD1
gene id: 93934:ENTPD1
uniprot id: A0A8C2UA46
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:ADPRH
gene id: 93934:ADPRH
uniprot id: A0A8C2SWN0
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

93934:NR5A1
gene id: 93934:NR5A1
uniprot id: A0A8C2THW9
uniprot id: Q08JW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR5 subfamily.
messages: Nucleus

93934:PLCZ1
gene id: 93934:PLCZ1
uniprot id: A9CQL7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca(2+)-dependent manner. Triggers intracellular Ca(2+) oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
messages: perinuclear region

93934:CARTPT
gene id: 93934:CARTPT
uniprot id: A0A8C2T324
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CART family.
messages: Secreted

93934:RPL4
gene id: 93934:RPL4
uniprot id: A0A8C2UF24
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

93934:THYN1
gene id: 93934:THYN1
uniprot id: A0A8C2T560
names: Function
messages: Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.

93934:KCNJ13
gene id: 93934:KCNJ13
uniprot id: A0A8C2U1T5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

93934:LOC107325834
gene id: 93934:LOC107325834
uniprot id: A0A8C2SW95
names: Similarity
messages: Belongs to the intermediate filament family.

93934:RHCE
gene id: 93934:RHCE
uniprot id: A0A8C2TXM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

93934:HIP1
gene id: 93934:HIP1
uniprot id: A0A8C2SV32
names: Similarity
messages: Belongs to the SLA2 family.

93934:NIPSNAP2
gene id: 93934:NIPSNAP2
uniprot id: A0A8C2TF31
names: Similarity
messages: Belongs to the NipSnap family.

93934:TYR
gene id: 93934:TYR
uniprot id: Q8UUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

93934:NDUFAF1
gene id: 93934:NDUFAF1
uniprot id: A0A8C2TRL7
names: Function
names: Similarity
messages: As part of the MCIA complex, involved in the assembly of the mitochondrial complex I.
messages: Belongs to the CIA30 family.

93934:PLK1
gene id: 93934:PLK1
uniprot id: A0A8C2TFV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.
messages: Midbody
messages: Nucleus
messages: centrosome

93934:TMEM39B
gene id: 93934:TMEM39B
uniprot id: A0A8C2SL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM39 family.
messages: Membrane

93934:SFXN3
gene id: 93934:SFXN3
uniprot id: A0A8C2UD68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

93934:MAS1
gene id: 93934:MAS1
uniprot id: A0A8C2Y785
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:USP2
gene id: 93934:USP2
uniprot id: A0A8C2TDW3
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:LOC107321228
gene id: 93934:LOC107321228
uniprot id: A0A8C2TBI3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

93934:ELOVL3
gene id: 93934:ELOVL3
uniprot id: A0A8C2U6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

93934:CRABP2
gene id: 93934:CRABP2
uniprot id: A0A8C2TV21
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:DGCR2
gene id: 93934:DGCR2
uniprot id: A0A8C2T837
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:GYS2
gene id: 93934:GYS2
uniprot id: A0A8C2STT3
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

93934:LOC107312330
gene id: 93934:LOC107312330
uniprot id: A0A8C2SNV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-17 family.
messages: Secreted

93934:CDCA7
gene id: 93934:CDCA7
uniprot id: A0A8C2YF87
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:PSMD3
gene id: 93934:PSMD3
uniprot id: A0A8C2SRV7
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

93934:UBE4A
gene id: 93934:UBE4A
uniprot id: A0A8C2TBU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

93934:SPCS1
gene id: 93934:SPCS1
uniprot id: A0A8C2SYZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:DCP1B
gene id: 93934:DCP1B
uniprot id: A0A8C2UCX9
names: Similarity
messages: Belongs to the DCP1 family.

93934:FOXK2
gene id: 93934:FOXK2
uniprot id: A0A8C2UGC9
names: Subcellular Location Annotation
messages: Nucleus

93934:KIZ
gene id: 93934:KIZ
uniprot id: A0A8C2YDX3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the kizuna family.
messages: Centrosomal protein required for establishing a robust mitotic centrosome architecture that can endure the forces that converge on the centrosomes during spindle formation. Required for stabilizing the expanded pericentriolar material around the centriole.
messages: centrosome
messages: cilium basal body

93934:GRAMD1B
gene id: 93934:GRAMD1B
uniprot id: A0A8C2TAK2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:DOCK8
gene id: 93934:DOCK8
uniprot id: A0A8C2Y5S6
names: Similarity
messages: Belongs to the DOCK family.

93934:LOC107318581
gene id: 93934:LOC107318581
uniprot id: A0A8C2YC13
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

93934:LOC107320185
gene id: 93934:LOC107320185
uniprot id: A0A8C2SYX0
uniprot id: A0A8C2T242
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers.
messages: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes.

93934:GCH1
gene id: 93934:GCH1
uniprot id: A0A8C2T0Y0
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

93934:HOXB8
gene id: 93934:HOXB8
uniprot id: A0A8C2U9R3
names: Subcellular Location Annotation
messages: Nucleus

93934:TMEM242
gene id: 93934:TMEM242
uniprot id: A0A8C2T5L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM242 family.
messages: Membrane

93934:LAMA5
gene id: 93934:LAMA5
uniprot id: A0A8C2SRH8
uniprot id: A0A8C2ST35
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

93934:CNN3
gene id: 93934:CNN3
uniprot id: A0A8C2SN41
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

93934:GRAMD1C
gene id: 93934:GRAMD1C
uniprot id: A0A8C2U4I2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TRUB1
gene id: 93934:TRUB1
uniprot id: A0A8C2YGX0
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

93934:UBA2
gene id: 93934:UBA2
uniprot id: A0A8C2TVF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer of SAE1 and UBA2/SAE2. The heterodimer corresponds to the two domains that are encoded on a single polypeptide chain in ubiquitin-activating enzyme E1. Interacts with UBE2I.
messages: Nucleus
messages: The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2.

93934:GPAT4
gene id: 93934:GPAT4
uniprot id: A0A8C2YDM4
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:TIPARP
gene id: 93934:TIPARP
uniprot id: A0A8C2U8S7
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:LOC107321032
gene id: 93934:LOC107321032
uniprot id: A0A8C2U669
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

93934:NUBP2
gene id: 93934:NUBP2
uniprot id: A0A8C2YES6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NUBP1 and two labile, bridging clusters between subunits of the NUBP1-NUBP2 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins.
messages: Cytoplasm
messages: Heterotetramer of 2 NUBP1 and 2 NUBP2 chains.

93934:MEIS1
gene id: 93934:MEIS1
uniprot id: A0A8C2TKP2
uniprot id: A0A8C2TM21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

93934:LOC107314287
gene id: 93934:LOC107314287
uniprot id: A0A8C2TP57
names: Similarity
messages: Belongs to the CD225/Dispanin family.

93934:STAC
gene id: 93934:STAC
uniprot id: A0A8C2TVT7
names: Subcellular Location Annotation
messages: sarcolemma

93934:CRYBG3
gene id: 93934:CRYBG3
uniprot id: A0A8C2Y572
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

93934:INO80C
gene id: 93934:INO80C
uniprot id: A0A8C2YDB5
names: Subcellular Location Annotation
messages: Nucleus

93934:XPOT
gene id: 93934:XPOT
uniprot id: A0A8C2TZU7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

93934:FOXN2
gene id: 93934:FOXN2
uniprot id: A0A8C2SNR3
names: Subcellular Location Annotation
messages: Nucleus

93934:AHCYL1
gene id: 93934:AHCYL1
uniprot id: A0A8C2TBC9
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

93934:SLC37A1
gene id: 93934:SLC37A1
uniprot id: A0A8C2TA55
uniprot id: A0A8C2Y9I5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93934:AHCY
gene id: 93934:AHCY
uniprot id: A0A8C2UHP1
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

93934:P2RY8
gene id: 93934:P2RY8
uniprot id: A0A8C2U7L9
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CCNB3
gene id: 93934:CCNB3
uniprot id: A0A8C2T2E5
names: Similarity
messages: Belongs to the cyclin family.

93934:TNFAIP2
gene id: 93934:TNFAIP2
uniprot id: A0A8C2STU9
names: Similarity
messages: Belongs to the SEC6 family.

93934:LOC107310113
gene id: 93934:LOC107310113
uniprot id: A0A8C2TC24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transthyretin family.
messages: Homotetramer.
messages: Secreted
messages: Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

93934:ABCC9
gene id: 93934:ABCC9
uniprot id: A0A8C2STE6
uniprot id: A0A8C2STR5
uniprot id: A0A8C2SUW0
names: Subunit
messages: Interacts with KCNJ11.

93934:PPARA
gene id: 93934:PPARA
uniprot id: A0A8C2TZK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

93934:TBP
gene id: 93934:TBP
uniprot id: A0A8C2SU35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

93934:ACAA1
gene id: 93934:ACAA1
uniprot id: A0A8C2TFC4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93934:CYFIP1
gene id: 93934:CYFIP1
uniprot id: A0A8C2U7S0
names: Similarity
messages: Belongs to the CYFIP family.

93934:ACSF3
gene id: 93934:ACSF3
uniprot id: A0A8C2YDF8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:UBE2K
gene id: 93934:UBE2K
uniprot id: A0A8C2U2H0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:TEKT5
gene id: 93934:TEKT5
uniprot id: A0A8C2TZW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

93934:GALR2
gene id: 93934:GALR2
uniprot id: A0A8C2UF66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:JPH2
gene id: 93934:JPH2
uniprot id: A0A8C2SPK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

93934:ALDH18A1
gene id: 93934:ALDH18A1
uniprot id: A0A8C2SYE9
names: Similarity
messages: In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
messages: In the N-terminal section; belongs to the glutamate 5-kinase family.

93934:KCNC1
gene id: 93934:KCNC1
uniprot id: A0A8C2TEU2
names: Subcellular Location Annotation
messages: Membrane

93934:GTDC1
gene id: 93934:GTDC1
uniprot id: A0A8C2UET2
names: Similarity
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.

93934:ATP5F1C
gene id: 93934:ATP5F1C
uniprot id: A0A8C2SUY2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

93934:LOC107315831
gene id: 93934:LOC107315831
uniprot id: A0A8C2YAQ8
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

93934:LOC107312605
gene id: 93934:LOC107312605
uniprot id: A0A8C2UI97
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:LOC107305752
gene id: 93934:LOC107305752
uniprot id: A0A8C2T282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Cell membrane
messages: Membrane

93934:SMARCD3
gene id: 93934:SMARCD3
uniprot id: A0A8C2T508
names: Similarity
messages: Belongs to the SMARCD family.

93934:LOC107315244
gene id: 93934:LOC107315244
uniprot id: A0A8C2Y5W8
names: Similarity
messages: Belongs to the serpin family.

93934:NPR2
gene id: 93934:NPR2
uniprot id: A0A8C2T1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Membrane

93934:PAFAH1B1
gene id: 93934:PAFAH1B1
uniprot id: A0A8C2UCA5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Can self-associate. Interacts with dynein, dynactin, NDE1 and NDEL1.
messages: Dimerization mediated by the LisH domain may be required to activate dynein.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration.
messages: centrosome
messages: cytoskeleton

93934:ERAP1
gene id: 93934:ERAP1
uniprot id: A0A8C2TKN5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

93934:GLCE
gene id: 93934:GLCE
uniprot id: A0A8C2UGT9
names: Similarity
messages: Belongs to the D-glucuronyl C5-epimerase family.

93934:ADGRD2
gene id: 93934:ADGRD2
uniprot id: A0A8C2TK28
uniprot id: A0A8C2YAV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:APLNR
gene id: 93934:APLNR
uniprot id: A0A8C2YF37
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:TMCC3
gene id: 93934:TMCC3
uniprot id: A0A8C2SX54
names: Similarity
messages: Belongs to the TEX28 family.

93934:NCAPG
gene id: 93934:NCAPG
uniprot id: A0A8C2U6C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

93934:SCARB2
gene id: 93934:SCARB2
uniprot id: A0A8C2SLX6
uniprot id: A0A8C2Y4Y0
names: Similarity
messages: Belongs to the CD36 family.

93934:NANOS1
gene id: 93934:NANOS1
uniprot id: A0A8C2UCF8
names: Similarity
messages: Belongs to the nanos family.

93934:COPS7B
gene id: 93934:COPS7B
uniprot id: A0A8C2TSF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

93934:LOC107309939
gene id: 93934:LOC107309939
uniprot id: A0A8C2T5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFI6/IFI27 family.
messages: Membrane

93934:KCNMB4
gene id: 93934:KCNMB4
uniprot id: A0A8C2TZ51
names: Subcellular Location Annotation
messages: Membrane

93934:TMEM132C
gene id: 93934:TMEM132C
uniprot id: A0A8C2U8U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

93934:ACVR1B
gene id: 93934:ACVR1B
uniprot id: A0A8C2YFC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:RET
gene id: 93934:RET
uniprot id: A0A8C2TPA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.
messages: Cell membrane
messages: Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.

93934:RALYL
gene id: 93934:RALYL
uniprot id: A0A8C2SK22
uniprot id: A0A8C2SLN4
names: Similarity
messages: Belongs to the RRM HNRPC family. RALY subfamily.

93934:DMRTA2
gene id: 93934:DMRTA2
uniprot id: A0A8C2YAH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

93934:CRB2
gene id: 93934:CRB2
uniprot id: A0A8C2TII7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MAML3
gene id: 93934:MAML3
uniprot id: A0A8C2SNH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

93934:CNEP1R1
gene id: 93934:CNEP1R1
uniprot id: A0A8C2TS52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNEP1R1 family.
messages: Cytoplasm
messages: Membrane
messages: Nucleus membrane

93934:LOC107325066
gene id: 93934:LOC107325066
uniprot id: A0A8C2U965
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

93934:CXCR5
gene id: 93934:CXCR5
uniprot id: A0A8C2YBI8
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CTSH
gene id: 93934:CTSH
uniprot id: A0A8C2YHM8
names: Similarity
messages: Belongs to the peptidase C1 family.

93934:NFIA
gene id: 93934:NFIA
uniprot id: A0A8C2TJR2
uniprot id: A0A8C2TML7
uniprot id: A0A8C2YBR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

93934:FGF12
gene id: 93934:FGF12
uniprot id: A0A8C2TS03
uniprot id: A0A8C2TTN2
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:ARFGEF1
gene id: 93934:ARFGEF1
uniprot id: A0A8C2TJZ7
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

93934:SMIM19
gene id: 93934:SMIM19
uniprot id: A0A8C2SZX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMIM19 family.
messages: Membrane

93934:PHACTR1
gene id: 93934:PHACTR1
uniprot id: A0A8C2U1I2
uniprot id: A0A8C2U2N8
uniprot id: A0A8C2YEU8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Nucleus
messages: Synapse

93934:YPEL5
gene id: 93934:YPEL5
uniprot id: A0A8C2Y562
names: Similarity
messages: Belongs to the yippee family.

93934:UBE2D1
gene id: 93934:UBE2D1
uniprot id: A0A8C2TP31
uniprot id: A0A8C2YC22
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:PXN
gene id: 93934:PXN
uniprot id: A0A8C2YCE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paxillin family.
messages: cell cortex
messages: cytoskeleton
messages: focal adhesion

93934:MARCKSL1
gene id: 93934:MARCKSL1
uniprot id: A0A8C2Y519
names: Similarity
messages: Belongs to the MARCKS family.

93934:CGA
gene id: 93934:CGA
uniprot id: P68242
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycoprotein hormones subunit alpha family.
messages: Heterodimer. Glycoprotein hormones are heterodimers composed of a common alpha chain described here and a unique beta chain which confers their biological specificity to the different hormones.
messages: Secreted
messages: Shared alpha chain of heterodimeric glycoprotein hormones. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.

93934:FGF18
gene id: 93934:FGF18
uniprot id: A0A8C2YB11
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:ARL6IP5
gene id: 93934:ARL6IP5
uniprot id: A0A8C2U533
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

93934:VPS33A
gene id: 93934:VPS33A
uniprot id: A0A8C2UHX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STXBP/unc-18/SEC1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

93934:CCNL1
gene id: 93934:CCNL1
uniprot id: A0A8C2U377
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin L subfamily.
messages: Nucleus speckle
messages: nucleoplasm

93934:ITM2B
gene id: 93934:ITM2B
uniprot id: A0A8C2UB85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

93934:HSPA4
gene id: 93934:HSPA4
uniprot id: A0A8C2UFL0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm
messages: Interacts with TJP1/ZO-1.

93934:LOC107312555
gene id: 93934:LOC107312555
uniprot id: A0A8C2T7E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:LOC107315190
gene id: 93934:LOC107315190
uniprot id: A0A8C2SST8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the poly(A) polymerase family.
messages: Binds 2 magnesium ions. Also active with manganese.
messages: Nucleus
messages: Polymerase that creates the 3'-poly(A) tail of mRNA's.

93934:LOC107309567
gene id: 93934:LOC107309567
uniprot id: A0A8C2TUT0
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

93934:SBNO2
gene id: 93934:SBNO2
uniprot id: A0A8C2YAK7
names: Similarity
messages: Belongs to the SBNO family.

93934:EEF2
gene id: 93934:EEF2
uniprot id: A0A8C2TBX7
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

93934:CHMP7
gene id: 93934:CHMP7
uniprot id: A0A8C2TUI7
names: Similarity
messages: Belongs to the SNF7 family.

93934:LOC107317492
gene id: 93934:LOC107317492
uniprot id: B9A8Q3
names: Similarity
messages: Belongs to the folate receptor family.

93934:SOX9
gene id: 93934:SOX9
uniprot id: Q2NM26
names: Subcellular Location Annotation
messages: Nucleus

93934:COQ5
gene id: 93934:COQ5
uniprot id: A0A8C2TSZ8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

93934:ELP3
gene id: 93934:ELP3
uniprot id: A0A8C2TP97
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

93934:PHACTR3
gene id: 93934:PHACTR3
uniprot id: A0A8C2SR85
names: Similarity
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.

93934:TRNAU1AP
gene id: 93934:TRNAU1AP
uniprot id: A0A8C2YEC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

93934:PPP2R2A
gene id: 93934:PPP2R2A
uniprot id: A0A8C2YBK9
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

93934:NUP85
gene id: 93934:NUP85
uniprot id: A0A8C2UF33
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: nuclear pore complex

93934:VPS13B
gene id: 93934:VPS13B
uniprot id: A0A8C2SLN7
uniprot id: A0A8C2Y548
names: Similarity
messages: Belongs to the VPS13 family.

93934:OCLN
gene id: 93934:OCLN
uniprot id: A0A8C2TJ23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
messages: Membrane
messages: tight junction

93934:CHDH
gene id: 93934:CHDH
uniprot id: A0A8C2TL93
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

93934:AK6
gene id: 93934:AK6
uniprot id: A0A8C2SP04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
messages: Cajal body
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer and homodimer. Interacts with COIL (via C-terminus).
messages: nucleoplasm

93934:GLRA2
gene id: 93934:GLRA2
uniprot id: A0A8C2U3S8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

93934:CLNS1A
gene id: 93934:CLNS1A
uniprot id: A0A8C2SZA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pICln (TC 1.A.47) family.
messages: Nucleus

93934:ZGPAT
gene id: 93934:ZGPAT
uniprot id: A0A8C2Y801
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107316282
gene id: 93934:LOC107316282
uniprot id: A0A8C2UC99
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:VSIG1
gene id: 93934:VSIG1
uniprot id: A0A8C2U0G6
names: Subcellular Location Annotation
messages: Membrane

93934:MPHOSPH10
gene id: 93934:MPHOSPH10
uniprot id: A0A8C2TP45
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing.
messages: nucleolus

93934:TACSTD2
gene id: 93934:TACSTD2
uniprot id: A0A8C2TN00
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EPCAM family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:CCM2L
gene id: 93934:CCM2L
uniprot id: A0A8C2SZK8
names: Similarity
messages: Belongs to the CCM2 family.

93934:LOC107312365
gene id: 93934:LOC107312365
uniprot id: A0A8C2T9Y2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

93934:SERPINB5
gene id: 93934:SERPINB5
uniprot id: A0A8C2U3R4
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

93934:SLC66A2
gene id: 93934:SLC66A2
uniprot id: A0A8C2U4I3
names: Subcellular Location Annotation
messages: Membrane

93934:PIK3C3
gene id: 93934:PIK3C3
uniprot id: A0A8C2SYD1
uniprot id: A0A8C2SYD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.
messages: Midbody

93934:CCT8
gene id: 93934:CCT8
uniprot id: A0A8C2SYS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: cilium basal body

93934:CHRDL1
gene id: 93934:CHRDL1
uniprot id: A0A8C2U0C1
names: Subcellular Location Annotation
messages: Secreted

93934:LOC107318823
gene id: 93934:LOC107318823
uniprot id: A0A8C2UGI5
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

93934:AFAP1L1
gene id: 93934:AFAP1L1
uniprot id: A0A8C2T8I8
uniprot id: A0A8C2TDX0
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in podosome and invadosome formation.
messages: invadopodium
messages: podosome

93934:SMIM12
gene id: 93934:SMIM12
uniprot id: A0A8C2U2N0
names: Similarity
messages: Belongs to the SMIM12 family.

93934:CSGALNACT2
gene id: 93934:CSGALNACT2
uniprot id: A0A8C2TLB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

93934:EGFLAM
gene id: 93934:EGFLAM
uniprot id: A0A8C2T3D2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:BARHL1
gene id: 93934:BARHL1
uniprot id: A0A8C2T3I9
names: Subcellular Location Annotation
messages: Nucleus

93934:IL4I1
gene id: 93934:IL4I1
uniprot id: A0A8C2TWM1
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

93934:HS3ST5
gene id: 93934:HS3ST5
uniprot id: A0A8C2TA90
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:TFAP2C
gene id: 93934:TFAP2C
uniprot id: A0A8C2T3I3
names: Similarity
messages: Belongs to the AP-2 family.

93934:SLC25A4
gene id: 93934:SLC25A4
uniprot id: A0A8C2TE50
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

93934:SLC44A5
gene id: 93934:SLC44A5
uniprot id: A0A8C2TV85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Choline transporter.
messages: Membrane

93934:WDR48
gene id: 93934:WDR48
uniprot id: A0A8C2TFE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat WDR48 family.
messages: Endosome
messages: Late endosome

93934:LOC107325298
gene id: 93934:LOC107325298
uniprot id: A0A8C2Y7H3
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

93934:NPFFR1
gene id: 93934:NPFFR1
uniprot id: Q5KSL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

93934:YJU2
gene id: 93934:YJU2
uniprot id: A0A8C2TE35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex.

93934:HHEX
gene id: 93934:HHEX
uniprot id: A0A8C2YGF7
names: Subcellular Location Annotation
messages: Nucleus

93934:APC2
gene id: 93934:APC2
uniprot id: A0A8C2TGC9
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

93934:CPZ
gene id: 93934:CPZ
uniprot id: A0A8C2YFU5
names: Caution
names: Similarity
messages: Belongs to the peptidase M14 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:YIPF7
gene id: 93934:YIPF7
uniprot id: A0A8C2TZL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

93934:COG7
gene id: 93934:COG7
uniprot id: A0A8C2TI95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG7 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:PGPEP1
gene id: 93934:PGPEP1
uniprot id: A0A8C2TLV4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C15 family.
messages: Cytoplasm
messages: Removes 5-oxoproline from various penultimate amino acid residues except L-proline.

93934:ELF5
gene id: 93934:ELF5
uniprot id: A0A8C2TZI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:CALHM3
gene id: 93934:CALHM3
uniprot id: A0A8C2UDY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

93934:LOC107320658
gene id: 93934:LOC107320658
uniprot id: A0A8C2TG53
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CLIC5
gene id: 93934:CLIC5
uniprot id: A0A8C2Y5Q9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

93934:PIGG
gene id: 93934:PIGG
uniprot id: A0A8C2TIM8
uniprot id: A0A8C2TLB4
uniprot id: A0A8C2TM41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TMTC3
gene id: 93934:TMTC3
uniprot id: A0A8C2SYN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

93934:GUSB
gene id: 93934:GUSB
uniprot id: A0A8C2TFL7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Homotetramer.
messages: Inhibited by L-aspartic acid.
messages: Lysosome
messages: Plays an important role in the degradation of dermatan and keratan sulfates.

93934:TRHDE
gene id: 93934:TRHDE
uniprot id: A0A8C2TXU8
names: Similarity
messages: Belongs to the peptidase M1 family.

93934:CTNND1
gene id: 93934:CTNND1
uniprot id: A0A8C2U5P8
names: Similarity
messages: Belongs to the beta-catenin family.

93934:LIPH
gene id: 93934:LIPH
uniprot id: A0A8C2UC54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

93934:NPRL2
gene id: 93934:NPRL2
uniprot id: A0A8C2Y7Q1
names: Similarity
messages: Belongs to the NPR2 family.

93934:SLC13A4
gene id: 93934:SLC13A4
uniprot id: A0A8C2UAC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

93934:FAM20C
gene id: 93934:FAM20C
uniprot id: A0A8C2TUA0
names: Similarity
messages: Belongs to the FAM20 family.

93934:HDDC2
gene id: 93934:HDDC2
uniprot id: A0A8C2Y9S7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

93934:LOC107308407
gene id: 93934:LOC107308407
uniprot id: A0A8C2STI5
names: Similarity
messages: Belongs to the peptidase M10A family.

93934:EPN2
gene id: 93934:EPN2
uniprot id: A0A8C2SVC6
names: Similarity
messages: Belongs to the epsin family.

93934:UBALD2
gene id: 93934:UBALD2
uniprot id: A0A8C2UD13
names: Similarity
messages: Belongs to the UBALD family.

93934:MDGA1
gene id: 93934:MDGA1
uniprot id: A0A8C2TDG2
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:REXO4
gene id: 93934:REXO4
uniprot id: A0A8C2Y870
names: Similarity
messages: Belongs to the REXO4 family.

93934:CACNA2D1
gene id: 93934:CACNA2D1
uniprot id: A0A8C2Y720
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

93934:CPEB2
gene id: 93934:CPEB2
uniprot id: A0A8C2U451
uniprot id: A0A8C2U863
names: Similarity
messages: Belongs to the RRM CPEB family.

93934:LHX3
gene id: 93934:LHX3
uniprot id: A0A8C2T963
names: Subcellular Location Annotation
messages: Nucleus

93934:ALDH1A2
gene id: 93934:ALDH1A2
uniprot id: A0A8C2U1L0
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93934:SLC25A51
gene id: 93934:SLC25A51
uniprot id: A0A8C2T1D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:SLITRK1
gene id: 93934:SLITRK1
uniprot id: A0A8C2UA69
names: Similarity
messages: Belongs to the SLITRK family.

93934:MRPL32
gene id: 93934:MRPL32
uniprot id: A0A8C2Y4P0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

93934:LPCAT3
gene id: 93934:LPCAT3
uniprot id: A0A8C2TZ92
names: Subcellular Location Annotation
messages: Membrane

93934:DLGAP5
gene id: 93934:DLGAP5
uniprot id: A0A8C2Y7T2
names: Similarity
messages: Belongs to the SAPAP family.

93934:CD34
gene id: 93934:CD34
uniprot id: A0A8C2TW61
names: Subcellular Location Annotation
messages: Membrane

93934:TNKS
gene id: 93934:TNKS
uniprot id: A0A8C2TG33
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:TUBD1
gene id: 93934:TUBD1
uniprot id: A0A8C2U660
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Nucleus
messages: centriole
messages: cilium

93934:PITX1
gene id: 93934:PITX1
uniprot id: A0A8C2T187
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

93934:ABHD12
gene id: 93934:ABHD12
uniprot id: A0A8C2TXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the serine esterase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:GNPDA1
gene id: 93934:GNPDA1
uniprot id: A0A8C2UGI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family.
messages: Cytoplasm
messages: Homohexamer.

93934:ALKAL2
gene id: 93934:ALKAL2
uniprot id: A0A8C2T950
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALKAL family.
messages: Secreted

93934:HS3ST1
gene id: 93934:HS3ST1
uniprot id: A0A8C2U6T6
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:TPM1
gene id: 93934:TPM1
uniprot id: A0A8C2TBY3
uniprot id: A0A8C2Y9G2
uniprot id: A0A8C2Y9M9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

93934:MRPL41
gene id: 93934:MRPL41
uniprot id: A0A8C2TZZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

93934:ACRBP
gene id: 93934:ACRBP
uniprot id: A0A8C2TYR8
names: Subcellular Location Annotation
messages: acrosome

93934:LOC107314127
gene id: 93934:LOC107314127
uniprot id: A0A8C2TPB3
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CTH
gene id: 93934:CTH
uniprot id: A0A8C2YD87
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93934:RGS5
gene id: 93934:RGS5
uniprot id: A0A8C2UEN4
names: Function
messages: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i)-alpha and G(o)-alpha, but not to G(s)-alpha.

93934:LIG3
gene id: 93934:LIG3
uniprot id: A0A8C2TCF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent DNA ligase family.
messages: Nucleus

93934:GSTZ1
gene id: 93934:GSTZ1
uniprot id: A0A8C2YGB6
uniprot id: A0A8C2YGD0
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

93934:LOC107319329
gene id: 93934:LOC107319329
uniprot id: A0A8C2TUK9
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

93934:LOC107306595
gene id: 93934:LOC107306595
uniprot id: A0A8C2Y664
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Photoreceptor outer segment membrane

93934:BCLAF3
gene id: 93934:BCLAF3
uniprot id: A0A8C2YF18
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

93934:EYA3
gene id: 93934:EYA3
uniprot id: A0A8C2TV49
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

93934:GPT2
gene id: 93934:GPT2
uniprot id: A0A8C2TUL5
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

93934:KEF80 p10
gene id: 93934:KEF80_p10
uniprot id: A0A1D9CQQ6
uniprot id: P50684
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 2 family.
messages: Binds a copper A center.
messages: Binds a dinuclear copper A center per subunit.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). Found in a complex with TMEM177, COA6, COX18, COX20, SCO1 and SCO2. Interacts with TMEM177 in a COX20-dependent manner. Interacts with COX20. Interacts with COX16 (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

93934:PLD4
gene id: 93934:PLD4
uniprot id: A0A8C2SUR9
names: Similarity
messages: Belongs to the phospholipase D family.

93934:DUSP26
gene id: 93934:DUSP26
uniprot id: A0A8C2TTC9
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

93934:PLBD1
gene id: 93934:PLBD1
uniprot id: A0A8C2T8S8
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

93934:AP2B1
gene id: 93934:AP2B1
uniprot id: A0A8C2TCD3
uniprot id: A0A8C2TDX4
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

93934:ALX4
gene id: 93934:ALX4
uniprot id: A0A8C2TGQ8
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107309008
gene id: 93934:LOC107309008
uniprot id: A0A8C2TCI0
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:FAM160A2
gene id: 93934:FAM160A2
uniprot id: A0A8C2T3J8
names: Similarity
messages: Belongs to the FHIP family.

93934:LHX2
gene id: 93934:LHX2
uniprot id: A0A8C2TGX7
names: Subcellular Location Annotation
messages: Nucleus

93934:PDCD11
gene id: 93934:PDCD11
uniprot id: A0A8C2UA29
uniprot id: A0A8C2UD97
names: Subcellular Location Annotation
messages: nucleolus

93934:ARGLU1
gene id: 93934:ARGLU1
uniprot id: A0A8C2U1H0
names: Similarity
messages: Belongs to the UPF0430 family.

93934:BVES
gene id: 93934:BVES
uniprot id: A0A8C2TAZ7
uniprot id: A0A8C2TDM8
names: Similarity
messages: Belongs to the popeye family.

93934:CCN3
gene id: 93934:CCN3
uniprot id: P42642
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Cytoplasm
messages: Immediate-early protein likely to play a role in cell growth regulation.
messages: Secreted
messages: gap junction

93934:MIDN
gene id: 93934:MIDN
uniprot id: A0A8C2TI34
names: Subcellular Location Annotation
messages: Nucleus

93934:LGR5
gene id: 93934:LGR5
uniprot id: A0A8C2TZ95
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:CDC73
gene id: 93934:CDC73
uniprot id: A0A8C2YHP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC73 family.
messages: Nucleus

93934:GDF11
gene id: 93934:GDF11
uniprot id: A0A8C2Y6E8
names: Similarity
messages: Belongs to the TGF-beta family.

93934:NIP7
gene id: 93934:NIP7
uniprot id: A0A8C2TY77
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

93934:FAM126A
gene id: 93934:FAM126A
uniprot id: A0A8C2TLF3
uniprot id: A0A8C2TME1
uniprot id: A0A8C2YBH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

93934:SCAMP2
gene id: 93934:SCAMP2
uniprot id: A0A8C2T9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

93934:LOC107312790
gene id: 93934:LOC107312790
uniprot id: A0A8C2YET6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

93934:XRCC5
gene id: 93934:XRCC5
uniprot id: A0A8C2TQC4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: Single-stranded DNA-dependent ATP-dependent helicase.

93934:RPL8
gene id: 93934:RPL8
uniprot id: A0A8C2TQK0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

93934:INSIG2
gene id: 93934:INSIG2
uniprot id: A0A8C2UDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Mediates feedback control of cholesterol synthesis.
messages: Membrane

93934:PDE6C
gene id: 93934:PDE6C
uniprot id: A0A8C2UAX3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:NUDT12
gene id: 93934:NUDT12
uniprot id: A0A8C2TD57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nudix hydrolase family. NudC subfamily.
messages: Cytoplasmic granule
messages: Peroxisome

93934:ISCA2
gene id: 93934:ISCA2
uniprot id: A0A8C2U9F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HesB/IscA family.
messages: Mitochondrion

93934:HOXB2
gene id: 93934:HOXB2
uniprot id: A0A8C2UD28
names: Subcellular Location Annotation
messages: Nucleus

93934:TMTC2
gene id: 93934:TMTC2
uniprot id: A0A8C2SXR5
uniprot id: A0A8C2SZY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

93934:ACER3
gene id: 93934:ACER3
uniprot id: A0A8C2Y768
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TXN
gene id: 93934:TXN
uniprot id: A0A8C2SX08
names: Similarity
messages: Belongs to the thioredoxin family.

93934:CAMK1G
gene id: 93934:CAMK1G
uniprot id: A0A8C2U230
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:BCHE
gene id: 93934:BCHE
uniprot id: A0A8C2YFF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Secreted

93934:UNC50
gene id: 93934:UNC50
uniprot id: A0A8C2SP77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane
messages: Nucleus inner membrane

93934:ANO4
gene id: 93934:ANO4
uniprot id: A0A8C2T418
uniprot id: A0A8C2T4G7
uniprot id: A0A8C2T514
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:KYAT3
gene id: 93934:KYAT3
uniprot id: A0A8C2T768
names: Subunit
messages: Homodimer.

93934:CXXC5
gene id: 93934:CXXC5
uniprot id: A0A8C2TMQ4
names: Subcellular Location Annotation
messages: Cytoplasm

93934:HOGA1
gene id: 93934:HOGA1
uniprot id: A0A8C2YGJ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the final step in the metabolic pathway of hydroxyproline.
messages: Homotetramer.

93934:XPO1
gene id: 93934:XPO1
uniprot id: A0A8C2TZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm

93934:DUSP16
gene id: 93934:DUSP16
uniprot id: A0A8C2U1H8
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

93934:MTNR1B
gene id: 93934:MTNR1B
uniprot id: A0A8C2SW82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:AGMAT
gene id: 93934:AGMAT
uniprot id: A0A8C2U986
names: Similarity
messages: Belongs to the arginase family. Agmatinase subfamily.

93934:FSIP1
gene id: 93934:FSIP1
uniprot id: A0A8C2TYN8
uniprot id: A0A8C2TYQ5
uniprot id: A0A8C2U132
names: Similarity
messages: Belongs to the FSIP1 family.

93934:DPYSL5
gene id: 93934:DPYSL5
uniprot id: A0A8C2YBL6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

93934:ST3GAL4
gene id: 93934:ST3GAL4
uniprot id: A0A8C2T1J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:SHOC2
gene id: 93934:SHOC2
uniprot id: A0A8C2UC34
names: Function
names: Similarity
messages: Belongs to the SHOC2 family.
messages: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.

93934:ZC3H12B
gene id: 93934:ZC3H12B
uniprot id: A0A8C2SR77
names: Similarity
messages: Belongs to the ZC3H12 family.

93934:RELN
gene id: 93934:RELN
uniprot id: A0A8C2T4H0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the reelin family.
messages: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Oligomer of disulfide-linked homodimers. Binds to the ectodomains of VLDLR and LRP8/APOER2.
messages: extracellular matrix

93934:GGPS1
gene id: 93934:GGPS1
uniprot id: A0A8C2SPG2
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

93934:SLC25A46
gene id: 93934:SLC25A46
uniprot id: A0A8C2TDM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:MOGAT1
gene id: 93934:MOGAT1
uniprot id: A0A8C2Y7Q3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:WNT4
gene id: 93934:WNT4
uniprot id: A0A8C2T2T2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:CDKAL1
gene id: 93934:CDKAL1
uniprot id: A0A8C2U6L7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. CDKAL1 subfamily.
messages: Binds 1 or 2 [4Fe-4S] cluster. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-threonylcarbamoyladenosine (t(6)A), leading to the formation of 2-methylthio-N6-threonylcarbamoyladenosine (ms(2)t(6)A) at position 37 in tRNAs that read codons beginning with adenine.
messages: Endoplasmic reticulum membrane

93934:SNTB2
gene id: 93934:SNTB2
uniprot id: A0A8C2TXS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

93934:TRPV1
gene id: 93934:TRPV1
uniprot id: A0A8C2TYD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. TrpV subfamily. TRPV1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: dendritic spine membrane

93934:PSMD7
gene id: 93934:PSMD7
uniprot id: A0A8C2SM25
names: Similarity
messages: Belongs to the peptidase M67A family.

93934:PPP4R3A
gene id: 93934:PPP4R3A
uniprot id: A0A8C2SQM8
names: Similarity
messages: Belongs to the SMEK family.

93934:LOC107311976
gene id: 93934:LOC107311976
uniprot id: A0A8C2SUI3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:LOC107314066
gene id: 93934:LOC107314066
uniprot id: A0A8C2SXV4
names: Similarity
messages: Belongs to the SLBP family.

93934:ISY1
gene id: 93934:ISY1
uniprot id: A0A8C2TNS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

93934:EPHA3
gene id: 93934:EPHA3
uniprot id: A0A8C2U3Z4
names: Subcellular Location Annotation
messages: Membrane

93934:TMEM63B
gene id: 93934:TMEM63B
uniprot id: A0A8C2YAZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

93934:LOC107313656
gene id: 93934:LOC107313656
uniprot id: A0A8C2T658
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

93934:SKAP1
gene id: 93934:SKAP1
uniprot id: A0A8C2UB62
names: Similarity
messages: Belongs to the SKAP family.

93934:FAM171A1
gene id: 93934:FAM171A1
uniprot id: A0A8C2T4U1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM171 family.
messages: Membrane

93934:TBL1X
gene id: 93934:TBL1X
uniprot id: A0A8C2U3K0
names: Similarity
messages: Belongs to the WD repeat EBI family.

93934:ERH
gene id: 93934:ERH
uniprot id: A0A8C2TY97
names: Function
names: Similarity
messages: Belongs to the E(R) family.
messages: May have a role in the cell cycle.

93934:TADA2B
gene id: 93934:TADA2B
uniprot id: A0A8C2U768
names: Subcellular Location Annotation
messages: Nucleus

93934:NAIF1
gene id: 93934:NAIF1
uniprot id: A0A8C2UEZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAIF1 family.
messages: Induces apoptosis.
messages: Nucleus

93934:POU3F4
gene id: 93934:POU3F4
uniprot id: A0A8C2U1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

93934:GPR157
gene id: 93934:GPR157
uniprot id: A0A8C2TJ68
names: Subcellular Location Annotation
messages: Membrane

93934:LIMK1
gene id: 93934:LIMK1
uniprot id: A0A8C2SYU7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

93934:ERI1
gene id: 93934:ERI1
uniprot id: A0A8C2YB29
names: Subcellular Location Annotation
messages: Cytoplasm

93934:ACP1
gene id: 93934:ACP1
uniprot id: A0A8C2Y976
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates.
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
messages: Cytoplasm

93934:BACE1
gene id: 93934:BACE1
uniprot id: A0A8C2TJF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A1 family.
messages: Membrane
messages: Membrane raft
messages: Recycling endosome
messages: trans-Golgi network

93934:FREM1
gene id: 93934:FREM1
uniprot id: A0A8C2T7P8
names: Similarity
messages: Belongs to the FRAS1 family.

93934:ARRDC2
gene id: 93934:ARRDC2
uniprot id: A0A8C2TM10
names: Similarity
messages: Belongs to the arrestin family.

93934:CLP1
gene id: 93934:CLP1
uniprot id: A0A8C2U5H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Component of the tRNA splicing endonuclease complex. Component of pre-mRNA cleavage complex II (CF-II).
messages: Nucleus
messages: Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; this phosphorylation event is a prerequisite for the subsequent ligation of the two exon halves and the production of a mature tRNA. Component of the pre-mRNA cleavage complex II (CF-II), which seems to be required for mRNA 3'-end formation. Also phosphorylates the 5'-terminus of exogenously introduced short interfering RNAs (siRNAs), which is a necessary prerequisite for their incorporation into the RNA-induced silencing complex (RISC). However, endogenous siRNAs and microRNAs (miRNAs) that are produced by the cleavage of dsRNA precursors by DICER1 already contain a 5'-phosphate group, so this protein may be dispensible for normal RNA-mediated gene silencing.

93934:CCDC103
gene id: 93934:CCDC103
uniprot id: A0A8C2YG49
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC103/PR46b family.
messages: Cytoplasm
messages: Dynein-attachment factor required for cilia motility.
messages: Homodimer.
messages: flagellum

93934:MASTL
gene id: 93934:MASTL
uniprot id: A0A8C2SXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Nucleus
messages: centrosome

93934:GABRA1
gene id: 93934:GABRA1
uniprot id: A0A8C2Y9J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:ENO2
gene id: 93934:ENO2
uniprot id: A0A8C2YEL7
uniprot id: A0A8C2YEM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

93934:KCNC4
gene id: 93934:KCNC4
uniprot id: A0A8C2TC27
uniprot id: A0A8C2TC89
names: Subcellular Location Annotation
messages: Membrane

93934:MAFK
gene id: 93934:MAFK
uniprot id: A0A8C2YCZ0
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

93934:CSNK1D
gene id: 93934:CSNK1D
uniprot id: A0A8C2UGF9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:TNFRSF21
gene id: 93934:TNFRSF21
uniprot id: A0A8C2SR13
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MAB21L1
gene id: 93934:MAB21L1
uniprot id: A0A8C2U9E6
names: Similarity
messages: Belongs to the mab-21 family.

93934:LAMA1
gene id: 93934:LAMA1
uniprot id: A0A8C2T7J9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: basement membrane

93934:LHFPL2
gene id: 93934:LHFPL2
uniprot id: A0A8C2TBC4
names: Subcellular Location Annotation
messages: Membrane

93934:P2RX4
gene id: 93934:P2RX4
uniprot id: A0A8C2UH03
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

93934:CASTOR1
gene id: 93934:CASTOR1
uniprot id: A0A8C2TVK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GATS family.
messages: cytosol

93934:GPX8
gene id: 93934:GPX8
uniprot id: A0A8C2SP15
names: Similarity
messages: Belongs to the glutathione peroxidase family.

93934:RIC8B
gene id: 93934:RIC8B
uniprot id: A0A8C2YFM9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the synembryn family.
messages: Cytoplasm
messages: Guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins by exchanging bound GDP for free GTP.
messages: Interacts with some GDP-bound G alpha proteins. Does not interact with G-alpha proteins when they are in complex with subunits beta and gamma.

93934:TCEA1
gene id: 93934:TCEA1
uniprot id: A0A8C2TDW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.
messages: Nucleus

93934:TRH
gene id: 93934:TRH
uniprot id: A0A8C2UFC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRH family.
messages: Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
messages: Secreted

93934:SLC7A6OS
gene id: 93934:SLC7A6OS
uniprot id: A0A8C2TKF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IWR1/SLC7A6OS family.
messages: Cytoplasm
messages: Directs RNA polymerase II nuclear import.
messages: Nucleus

93934:TMEM45A
gene id: 93934:TMEM45A
uniprot id: A0A8C2YF53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

93934:LOC107317657
gene id: 93934:LOC107317657
uniprot id: A0A8C2YBP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hcp beta-lactamase family.
messages: Mitochondrion intermembrane space

93934:EPHA1
gene id: 93934:EPHA1
uniprot id: A0A8C2TZG1
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107318690
gene id: 93934:LOC107318690
uniprot id: A0A8C2UAE8
names: Subcellular Location Annotation
messages: cytoskeleton

93934:SST
gene id: 93934:SST
uniprot id: A0A8C2TSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the somatostatin family.
messages: Secreted

93934:WASHC1
gene id: 93934:WASHC1
uniprot id: A0A8C2UER7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WASH1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Recycling endosome membrane

93934:HVCN1
gene id: 93934:HVCN1
uniprot id: A0A8C2SLE1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hydrogen channel family.
messages: Homodimer.
messages: Membrane

93934:CDK2AP1
gene id: 93934:CDK2AP1
uniprot id: A0A8C2UD59
names: Similarity
messages: Belongs to the CDK2AP family.

93934:LDAH
gene id: 93934:LDAH
uniprot id: A0A8C2TJD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

93934:RHPN1
gene id: 93934:RHPN1
uniprot id: A0A8C2TEH9
names: Similarity
messages: Belongs to the RHPN family.

93934:ANKLE2
gene id: 93934:ANKLE2
uniprot id: A0A8C2U6V4
names: Similarity
messages: Belongs to the ANKLE2 family.

93934:ABCG2
gene id: 93934:ABCG2
uniprot id: A0A8C2UB98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Cell membrane
messages: Membrane
messages: Mitochondrion membrane

93934:GGA1
gene id: 93934:GGA1
uniprot id: A0A8C2TS84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

93934:LOC107312385
gene id: 93934:LOC107312385
uniprot id: A0A8C2TCZ4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:GPR18
gene id: 93934:GPR18
uniprot id: A0A8C2TZ49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane

93934:PLCB1
gene id: 93934:PLCB1
uniprot id: A0A8C2STS2
names: Function
messages: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.

93934:PTPRG
gene id: 93934:PTPRG
uniprot id: A0A8C2U2P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 5 subfamily.
messages: Membrane

93934:ADCK1
gene id: 93934:ADCK1
uniprot id: A0A8C2UAZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Secreted

93934:BIVM
gene id: 93934:BIVM
uniprot id: A0A8C2YE46
names: Similarity
messages: Belongs to the BIVM family.

93934:POGLUT2
gene id: 93934:POGLUT2
uniprot id: A0A8C2TYL5
names: Similarity
messages: Belongs to the KDELC family.

93934:NDP
gene id: 93934:NDP
uniprot id: A0A8C2TPB6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:CHRND
gene id: 93934:CHRND
uniprot id: A0A8C2TP81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:MAPT
gene id: 93934:MAPT
uniprot id: A0A8C2U733
names: Subcellular Location Annotation
messages: Membrane
messages: axon
messages: cytoskeleton
messages: cytosol

93934:ATP6V1C1
gene id: 93934:ATP6V1C1
uniprot id: A0A8C2SNR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

93934:DARS2
gene id: 93934:DARS2
uniprot id: A0A8C2UGP0
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

93934:ST3GAL5
gene id: 93934:ST3GAL5
uniprot id: A0A8C2SY04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:IQSEC1
gene id: 93934:IQSEC1
uniprot id: A0A8C2YC17
names: Similarity
messages: Belongs to the BRAG family.

93934:POLR3F
gene id: 93934:POLR3F
uniprot id: A0A8C2SY11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

93934:DBR1
gene id: 93934:DBR1
uniprot id: A0A8C2U5P4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lariat debranching enzyme family.
messages: Nucleus

93934:E2F7
gene id: 93934:E2F7
uniprot id: A0A8C2U227
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

93934:EXTL2
gene id: 93934:EXTL2
uniprot id: A0A8C2UGY5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

93934:DHRS9
gene id: 93934:DHRS9
uniprot id: A0A8C2U7A8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:LOC107319847
gene id: 93934:LOC107319847
uniprot id: A0A8C2TSH9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:CRBN
gene id: 93934:CRBN
uniprot id: A0A8C2U933
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRBN family.
messages: Nucleus

93934:HHAT
gene id: 93934:HHAT
uniprot id: A0A8C2T5H2
names: Subcellular Location Annotation
messages: Membrane

93934:BEST3
gene id: 93934:BEST3
uniprot id: A0A8C2TWL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

93934:MAT2B
gene id: 93934:MAT2B
uniprot id: A0A8C2TDQ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family. MAT2B subfamily.
messages: Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain. Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain. NADP binding increases the affinity for MAT2A.
messages: Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.

93934:TM2D2
gene id: 93934:TM2D2
uniprot id: A0A8C2TU39
names: Subcellular Location Annotation
messages: Membrane

93934:DHFR
gene id: 93934:DHFR
uniprot id: A0A8C2SLL9
uniprot id: A0A8C2SPH6
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

93934:NCOA7
gene id: 93934:NCOA7
uniprot id: A0A8C2T9S1
uniprot id: A0A8C2TC48
names: Similarity
messages: Belongs to the OXR1 family.

93934:MAML1
gene id: 93934:MAML1
uniprot id: A0A8C2SYK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mastermind family.
messages: Nucleus speckle

93934:SRC
gene id: 93934:SRC
uniprot id: A0A8C2UFN0
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:AASS
gene id: 93934:AASS
uniprot id: A0A8C2TBJ6
names: Similarity
messages: In the C-terminal section; belongs to the saccharopine dehydrogenase family.
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

93934:CDK2AP2
gene id: 93934:CDK2AP2
uniprot id: A0A8C2TRV5
names: Similarity
messages: Belongs to the CDK2AP family.

93934:S100Z
gene id: 93934:S100Z
uniprot id: A0A8C2T5T6
names: Similarity
messages: Belongs to the S-100 family.

93934:KCNH5
gene id: 93934:KCNH5
uniprot id: A0A8C2Y7A1
names: Subcellular Location Annotation
messages: Membrane

93934:GLRX
gene id: 93934:GLRX
uniprot id: A0A8C2YC23
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

93934:VAT1L
gene id: 93934:VAT1L
uniprot id: A0A8C2YD84
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

93934:PCNA
gene id: 93934:PCNA
uniprot id: Q9DDF1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PCNA family.
messages: Homotrimer. Forms a complex with activator 1 heteropentamer in the presence of ATP (By similarity). Component of the replisome complex (By similarity).
messages: Monoubiquitinated by the UBE2B-RAD18 complex on Lys-164. Monoubiquitination at Lys-164 also takes place in undamaged proliferating cells, and is mediated by the DCX(DTL) complex, leading to enhance PCNA-dependent translesion DNA synthesis (By similarity).
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

93934:MARK1
gene id: 93934:MARK1
uniprot id: A0A8C2T5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: dendrite

93934:FOXL3
gene id: 93934:FOXL3
uniprot id: A0A8C2TTI5
names: Subcellular Location Annotation
messages: Nucleus

93934:CAND1
gene id: 93934:CAND1
uniprot id: A0A8C2TZ31
names: Similarity
messages: Belongs to the CAND family.

93934:TMEM138
gene id: 93934:TMEM138
uniprot id: A0A8C2TQR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM138 family.
messages: Membrane
messages: Required for ciliogenesis.
messages: Vacuole membrane
messages: cilium

93934:LOC107317087
gene id: 93934:LOC107317087
uniprot id: A0A8C2UDC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

93934:LOC107320698
gene id: 93934:LOC107320698
uniprot id: A0A8C2U6M4
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

93934:CIAO2B
gene id: 93934:CIAO2B
uniprot id: A0A8C2TRX7
names: Similarity
messages: Belongs to the MIP18 family.

93934:MGAT5
gene id: 93934:MGAT5
uniprot id: A0A8C2UBJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 18 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Secreted

93934:LOC107322571
gene id: 93934:LOC107322571
uniprot id: A0A8C2TEG2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5.

93934:TNFAIP3
gene id: 93934:TNFAIP3
uniprot id: A0A8C2T917
uniprot id: A0A8C2T975
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:B4GALNT3
gene id: 93934:B4GALNT3
uniprot id: A0A8C2UDI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

93934:PA2G4
gene id: 93934:PA2G4
uniprot id: A0A8C2SSX6
names: Similarity
messages: Belongs to the peptidase M24 family.

93934:MMAB
gene id: 93934:MMAB
uniprot id: A0A8C2TA43
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

93934:PBX1
gene id: 93934:PBX1
uniprot id: A0A8C2UJF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/PBX homeobox family.
messages: Nucleus

93934:TPM4
gene id: 93934:TPM4
uniprot id: A0A8C2TXP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tropomyosin family.
messages: cytoskeleton

93934:VANGL1
gene id: 93934:VANGL1
uniprot id: A0A8C2YF15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Vang family.
messages: Cell membrane
messages: Membrane

93934:LOC107323823
gene id: 93934:LOC107323823
uniprot id: A0A8C2YEU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family.
messages: P-body

93934:CHCHD4
gene id: 93934:CHCHD4
uniprot id: A0A8C2YE74
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

93934:DYNC1LI2
gene id: 93934:DYNC1LI2
uniprot id: A0A8C2TSI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
messages: Belongs to the dynein light intermediate chain family.
messages: Homodimer. The cytoplasmic dynein 1 complex consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits presented by intermediate chains (ICs).
messages: cytoskeleton

93934:GDF7
gene id: 93934:GDF7
uniprot id: A0A8C2TLB9
names: Similarity
messages: Belongs to the TGF-beta family.

93934:LOC107312125
gene id: 93934:LOC107312125
uniprot id: A0A8C2T843
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

93934:SLC25A44
gene id: 93934:SLC25A44
uniprot id: A0A8C2TT47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:ADAMTS10
gene id: 93934:ADAMTS10
uniprot id: A0A8C2YA25
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:SULT4A1
gene id: 93934:SULT4A1
uniprot id: A0A8C2TW07
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:POP4
gene id: 93934:POP4
uniprot id: A0A8C2TUM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
messages: Component of nuclear RNase P and RNase MRP.
messages: Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends.
messages: nucleolus

93934:LOC107320994
gene id: 93934:LOC107320994
uniprot id: A0A8C2U2V0
names: Similarity
messages: Belongs to the globin family.

93934:GAD2
gene id: 93934:GAD2
uniprot id: A0A8C2SUB4
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

93934:LOC107318449
gene id: 93934:LOC107318449
uniprot id: A0A8C2T4I5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

93934:PPARG
gene id: 93934:PPARG
uniprot id: A0A8C2TPP7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Cytoplasm
messages: Heterodimer with other nuclear receptors.
messages: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. May play a role in the regulation of circadian rhythm.
messages: Nucleus

93934:CLEC16A
gene id: 93934:CLEC16A
uniprot id: A0A8C2TWJ6
names: Similarity
messages: Belongs to the CLEC16A/gop-1 family.

93934:LOC107316677
gene id: 93934:LOC107316677
uniprot id: A0A8C2SSZ2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:KEF80 p02
gene id: 93934:KEF80_p02
uniprot id: A0A8C2SLH0
uniprot id: P35075
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme b groups non-covalently.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
messages: Heme 1 (or BL or b562) is low-potential and absorbs at about 562 nm, and heme 2 (or BH or b566) is high-potential and absorbs at about 566 nm.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The cytochrome bc1 complex contains 11 subunits: 3 respiratory subunits (MT-CYB, CYC1 and UQCRFS1), 2 core proteins (UQCRC1 and UQCRC2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of UQCRFS1). This cytochrome bc1 complex then forms a dimer.
messages: The full-length protein contains only eight transmembrane helices, not nine as predicted by bioinformatics tools.

93934:LOC107322264
gene id: 93934:LOC107322264
uniprot id: A0A8C2UI97
names: Similarity
names: Subunit
messages: Belongs to the histone H3 family.
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:MAEA
gene id: 93934:MAEA
uniprot id: A0A8C2Y756
names: Subcellular Location Annotation
messages: Nucleus matrix

93934:RIOK1
gene id: 93934:RIOK1
uniprot id: A0A8C2U1Z6
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

93934:EPHX1
gene id: 93934:EPHX1
uniprot id: A0A8C2T3Q3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

93934:SLC9A1
gene id: 93934:SLC9A1
uniprot id: A0A8C2TWS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell membrane
messages: Membrane

93934:IGF2
gene id: 93934:IGF2
uniprot id: A0A8C2U549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

93934:MSTO1
gene id: 93934:MSTO1
uniprot id: A0A8C2YD16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the misato family.
messages: Mitochondrion outer membrane

93934:CHAT
gene id: 93934:CHAT
uniprot id: A0A8C2TNX4
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

93934:TIMM8A
gene id: 93934:TIMM8A
uniprot id: A0A8C2TI26
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

93934:TMEM230
gene id: 93934:TMEM230
uniprot id: A0A8C2TID0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM134/TMEM230 family.
messages: Early endosome
messages: Endosome
messages: Involved in trafficking and recycling of synaptic vesicles.
messages: Late endosome
messages: Membrane
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: synaptic vesicle
messages: trans-Golgi network

93934:PPP1R14C
gene id: 93934:PPP1R14C
uniprot id: A0A8C2T1C1
names: Similarity
messages: Belongs to the PP1 inhibitor family.

93934:INSM1
gene id: 93934:INSM1
uniprot id: A0A8C2TXM5
names: Subcellular Location Annotation
messages: Nucleus

93934:SCG3
gene id: 93934:SCG3
uniprot id: A0A8C2U9Z5
names: Subcellular Location Annotation
messages: Membrane
messages: Secreted
messages: secretory vesicle membrane

93934:KCNE1
gene id: 93934:KCNE1
uniprot id: A0A8C2T6V9
names: Similarity
messages: Belongs to the potassium channel KCNE family.

93934:PSMB7
gene id: 93934:PSMB7
uniprot id: A0A8C2THW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Within the 20S core complex, PSMB7 displays a trypsin-like activity.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is a barrel-shaped complex made of 28 subunits that are arranged in four stacked rings. The two outer rings are each formed by seven alpha subunits, and the two inner rings are formed by seven beta subunits. The proteolytic activity is exerted by three beta-subunits PSMB5, PSMB6 and PSMB7.

93934:RPL37
gene id: 93934:RPL37
uniprot id: A0A8C2Y8V5
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

93934:TPK1
gene id: 93934:TPK1
uniprot id: A0A8C2Y4X5
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

93934:PLPP1
gene id: 93934:PLPP1
uniprot id: A0A8C2SQ92
uniprot id: A0A8C2SQQ2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft
messages: caveola

93934:LOC107309600
gene id: 93934:LOC107309600
uniprot id: A0A8C2YEN3
names: Subcellular Location Annotation
messages: Membrane

93934:SLC1A7
gene id: 93934:SLC1A7
uniprot id: A0A8C2TJM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

93934:ANKRD13C
gene id: 93934:ANKRD13C
uniprot id: A0A8C2YD56
names: Subcellular Location Annotation
messages: Membrane

93934:PEX5
gene id: 93934:PEX5
uniprot id: A0A8C2TZG6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import.
messages: Cytoplasm
messages: Membrane

93934:CRLS1
gene id: 93934:CRLS1
uniprot id: A0A8C2T2I9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

93934:GNPTAB
gene id: 93934:GNPTAB
uniprot id: A0A8C2UEJ1
uniprot id: A0A8C2UGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stealth family.
messages: Membrane

93934:EFNA2
gene id: 93934:EFNA2
uniprot id: A0A8C2YAK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:ORC4
gene id: 93934:ORC4
uniprot id: A0A8C2UI33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication.
messages: Nucleus

93934:MFSD14A
gene id: 93934:MFSD14A
uniprot id: A0A8C2SK90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

93934:KIF3C
gene id: 93934:KIF3C
uniprot id: A0A8C2TLK8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:PACSIN1
gene id: 93934:PACSIN1
uniprot id: A0A8C2U2P4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytosol
messages: ruffle membrane
messages: synaptosome

93934:LOC107324276
gene id: 93934:LOC107324276
uniprot id: A0A8C2TL05
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

93934:STK10
gene id: 93934:STK10
uniprot id: A0A8C2Y9E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
messages: Cell membrane

93934:GNG4
gene id: 93934:GNG4
uniprot id: A0A8C2SNZ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:RPLP0
gene id: 93934:RPLP0
uniprot id: A0A8C2TQM5
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Ribosomal protein P0 is the functional equivalent of E.coli protein L10.

93934:ADRA2B
gene id: 93934:ADRA2B
uniprot id: A0A8C2TH66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:MIOX
gene id: 93934:MIOX
uniprot id: A0A8C2Y4R5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

93934:RNF43
gene id: 93934:RNF43
uniprot id: A0A8C2SWJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZNRF3 family.
messages: Cell membrane

93934:KCNK17
gene id: 93934:KCNK17
uniprot id: A0A8C2YAA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:COG2
gene id: 93934:COG2
uniprot id: A0A8C2Y6C6
names: Similarity
messages: Belongs to the COG2 family.

93934:FZD2
gene id: 93934:FZD2
uniprot id: A0A8C2U741
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TRMT44
gene id: 93934:TRMT44
uniprot id: A0A8C2U785
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

93934:NMNAT3
gene id: 93934:NMNAT3
uniprot id: A0A8C2SZU2
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

93934:CDC14A
gene id: 93934:CDC14A
uniprot id: A0A8C2UKV2
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

93934:RNFT1
gene id: 93934:RNFT1
uniprot id: A0A8C2U6A5
names: Subcellular Location Annotation
messages: Membrane

93934:SLC5A3
gene id: 93934:SLC5A3
uniprot id: A0A8C2T492
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:IL17REL
gene id: 93934:IL17REL
uniprot id: A0A8C2Y9C6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:BPNT2
gene id: 93934:BPNT2
uniprot id: A0A8C2TDY5
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93934:COPS3
gene id: 93934:COPS3
uniprot id: A0A8C2SR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN3 family.
messages: Cytoplasm
messages: Nucleus

93934:MED13
gene id: 93934:MED13
uniprot id: A0A8C2U5V0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:NDUFV3
gene id: 93934:NDUFV3
uniprot id: A0A8C2TAT2
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. May be the terminally assembled subunit of Complex I.
messages: Belongs to the complex I NDUFV3 subunit family.
messages: Complex I is composed of 45 different subunits. This is a component of the flavoprotein-sulfur (FP) fragment of the enzyme.

93934:CACHD1
gene id: 93934:CACHD1
uniprot id: A0A8C2YD48
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

93934:LETM2
gene id: 93934:LETM2
uniprot id: A0A8C2YDM1
names: Subcellular Location Annotation
messages: Membrane

93934:HTRA3
gene id: 93934:HTRA3
uniprot id: A0A8C2U9R0
names: Similarity
messages: Belongs to the peptidase S1C family.

93934:RHOT2
gene id: 93934:RHOT2
uniprot id: A0A8C2U1T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking.
messages: Mitochondrion outer membrane

93934:P2RY13
gene id: 93934:P2RY13
uniprot id: A0A8C2U7H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:HOXB1
gene id: 93934:HOXB1
uniprot id: A0A8C2U810
names: Subcellular Location Annotation
messages: Nucleus

93934:NPSR1
gene id: 93934:NPSR1
uniprot id: A0A8C2T7K6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:FGF14
gene id: 93934:FGF14
uniprot id: A0A8C2TYU9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:SPDL1
gene id: 93934:SPDL1
uniprot id: A0A8C2Y8L5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spindly family.
messages: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex.
messages: kinetochore

93934:BCL2L1
gene id: 93934:BCL2L1
uniprot id: A0A8C2T2M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Membrane
messages: Mitochondrion matrix
messages: Nucleus membrane
messages: centrosome
messages: cytosol
messages: synaptic vesicle membrane

93934:KDM5A
gene id: 93934:KDM5A
uniprot id: A0A8C2UFE4
names: Similarity
messages: Belongs to the JARID1 histone demethylase family.

93934:CCDC85A
gene id: 93934:CCDC85A
uniprot id: A0A8C2U0J6
uniprot id: A0A8C2YEI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

93934:RPS2
gene id: 93934:RPS2
uniprot id: A0A8C2SZ15
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays a role in the assembly and function of the 40S ribosomal subunit. Mutations in this protein affects the control of translational fidelity. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.

93934:CPT1A
gene id: 93934:CPT1A
uniprot id: A0A8C2U7R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the carnitine/choline acetyltransferase family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:MID2
gene id: 93934:MID2
uniprot id: A0A8C2T010
names: Subcellular Location Annotation
messages: cytoskeleton

93934:EARS2
gene id: 93934:EARS2
uniprot id: A0A8C2TG62
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

93934:TMEM208
gene id: 93934:TMEM208
uniprot id: A0A8C2TKX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: May function as a negative regulator of endoplasmic reticulum-stress induced autophagy.
messages: Membrane

93934:MAP2K1
gene id: 93934:MAP2K1
uniprot id: A0A8C2YHI6
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:ENPP3
gene id: 93934:ENPP3
uniprot id: A0A8C2T8T2
names: Subcellular Location Annotation
messages: Secreted

93934:SUDS3
gene id: 93934:SUDS3
uniprot id: A0A8C2TV78
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107320347
gene id: 93934:LOC107320347
uniprot id: A0A8C2TBK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

93934:POLR2D
gene id: 93934:POLR2D
uniprot id: A0A8C2TZC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

93934:NELFCD
gene id: 93934:NELFCD
uniprot id: A0A8C2T7B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NELF-D family.
messages: Nucleus

93934:SBF1
gene id: 93934:SBF1
uniprot id: A0A8C2SKX5
uniprot id: A0A8C2SNP0
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

93934:MED13L
gene id: 93934:MED13L
uniprot id: A0A8C2TXX4
uniprot id: A0A8C2YDU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:NCOA2
gene id: 93934:NCOA2
uniprot id: F2YL10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

93934:INPP5K
gene id: 93934:INPP5K
uniprot id: A0A8C2TIX5
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.

93934:C2H5orf22
gene id: 93934:C2H5orf22
uniprot id: A0A8C2TVC2
names: Similarity
messages: Belongs to the UPF0489 family.

93934:DAO
gene id: 93934:DAO
uniprot id: A0A8C2T3W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAMOX/DASOX family.
messages: Peroxisome

93934:MPI
gene id: 93934:MPI
uniprot id: A0A8C2T6P8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

93934:HSD17B2
gene id: 93934:HSD17B2
uniprot id: A0A8C2TXG3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:FBXO32
gene id: 93934:FBXO32
uniprot id: A0A8C2T2R8
names: Subcellular Location Annotation
messages: Nucleus

93934:KRT23
gene id: 93934:KRT23
uniprot id: A0A8C2SVZ9
names: Similarity
messages: Belongs to the intermediate filament family.

93934:ZNF703
gene id: 93934:ZNF703
uniprot id: A0A8C2TWZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

93934:SLC40A1
gene id: 93934:SLC40A1
uniprot id: A0A8C2TSS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily.
messages: May be involved in iron transport and iron homeostasis.
messages: Membrane

93934:ATG4A
gene id: 93934:ATG4A
uniprot id: A0A8C2U1W1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

93934:WSCD2
gene id: 93934:WSCD2
uniprot id: A0A8C2T6D7
names: Similarity
messages: Belongs to the WSCD family.

93934:VGLL3
gene id: 93934:VGLL3
uniprot id: A0A8C2SSJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.
messages: Nucleus

93934:C3H6orf120
gene id: 93934:C3H6orf120
uniprot id: A0A8C2SVV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0669 family.
messages: Secreted

93934:NUP58
gene id: 93934:NUP58
uniprot id: A0A8C2SMP4
uniprot id: A0A8C2SP16
names: Subcellular Location Annotation
messages: nuclear pore complex

93934:LOC107321031
gene id: 93934:LOC107321031
uniprot id: A0A8C2U982
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

93934:ARL3
gene id: 93934:ARL3
uniprot id: A0A8C2UF02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: centrosome

93934:ATP5PB
gene id: 93934:ATP5PB
uniprot id: A0A8C2U0W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(0) has three main subunits: a, b and c.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

93934:LOC107314168
gene id: 93934:LOC107314168
uniprot id: A0A8C2TQV3
names: Similarity
messages: Belongs to the glucagon family.

93934:LOC107324073
gene id: 93934:LOC107324073
uniprot id: A0A8C2Y7A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

93934:ITGB2
gene id: 93934:ITGB2
uniprot id: A0A8C2TLJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

93934:CELF5
gene id: 93934:CELF5
uniprot id: A0A8C2TEN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

93934:MBTPS2
gene id: 93934:MBTPS2
uniprot id: A0A8C2YEY0
names: Similarity
messages: Belongs to the peptidase M50A family.

93934:ZDHHC2
gene id: 93934:ZDHHC2
uniprot id: A0A8C2TE98
uniprot id: A0A8C2TEA3
uniprot id: A0A8C2THX6
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:SRPRB
gene id: 93934:SRPRB
uniprot id: A0A8C2Y5A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:P4HA1
gene id: 93934:P4HA1
uniprot id: A0A8C2TGT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

93934:PTPRB
gene id: 93934:PTPRB
uniprot id: A0A8C2TWB6
uniprot id: A0A8C2U104
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily.

93934:ETFDH
gene id: 93934:ETFDH
uniprot id: A0A8C2SP59
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

93934:SLC12A2
gene id: 93934:SLC12A2
uniprot id: A0A8C2TKU9
uniprot id: A0A8C2TLB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

93934:NAA30
gene id: 93934:NAA30
uniprot id: A0A8C2Y7R0
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

93934:DIPK2A
gene id: 93934:DIPK2A
uniprot id: A0A8C2TJY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

93934:OLFML2B
gene id: 93934:OLFML2B
uniprot id: A0A8C2YHP8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ATP5F1A
gene id: 93934:ATP5F1A
uniprot id: A0A8C2SZ10
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

93934:CKB
gene id: 93934:CKB
uniprot id: A0A8C2SR90
uniprot id: A0A8C2STE4
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

93934:CENPV
gene id: 93934:CENPV
uniprot id: A0A8C2YDW7
names: Similarity
messages: Belongs to the Gfa family.

93934:LOC107317020
gene id: 93934:LOC107317020
uniprot id: A0A8C2TLY6
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:LOC107320131
gene id: 93934:LOC107320131
uniprot id: A0A8C2SXU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:OAT
gene id: 93934:OAT
uniprot id: A0A8C2SM71
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93934:GATM
gene id: 93934:GATM
uniprot id: A0A8C2UCY2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the amidinotransferase family.
messages: Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine.
messages: Homodimer.
messages: Mitochondrion inner membrane

93934:TMEM35A
gene id: 93934:TMEM35A
uniprot id: A0A8C2TES2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Peroxisome membrane
messages: Vesicle

93934:MEMO1
gene id: 93934:MEMO1
uniprot id: A0A8C2YCM3
names: Similarity
messages: Belongs to the MEMO1 family.

93934:CCNH
gene id: 93934:CCNH
uniprot id: A0A8C2SNV5
names: Function
names: Similarity
names: Subunit
messages: Associates primarily with CDK7 and MAT1 to form the CAK complex. CAK can further associate with the core-TFIIH to form the TFIIH basal transcription factor.
messages: Belongs to the cyclin family.
messages: Regulates CDK7, the catalytic subunit of the CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II. Its expression and activity are constant throughout the cell cycle.

93934:ZPBP2
gene id: 93934:ZPBP2
uniprot id: A0A8C2SQC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the zona pellucida-binding protein Sp38 family.
messages: Secreted

93934:GDI2
gene id: 93934:GDI2
uniprot id: A0A8C2Y6F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP.

93934:LOC107325197
gene id: 93934:LOC107325197
uniprot id: A0A8C2SX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gastrin/cholecystokinin family.
messages: Secreted

93934:TTYH2
gene id: 93934:TTYH2
uniprot id: A0A8C2YHQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

93934:LOC107320998
gene id: 93934:LOC107320998
uniprot id: A0A8C2YFR5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

93934:SNX1
gene id: 93934:SNX1
uniprot id: A0A8C2SMF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium
messages: trans-Golgi network membrane

93934:DRGX
gene id: 93934:DRGX
uniprot id: A0A8C2UB19
names: Subcellular Location Annotation
messages: Nucleus

93934:SKA3
gene id: 93934:SKA3
uniprot id: A0A8C2SN63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKA3 family.
messages: kinetochore
messages: spindle

93934:FAM83A
gene id: 93934:FAM83A
uniprot id: A0A8C2Y7P1
names: Similarity
messages: Belongs to the FAM83 family.

93934:BRMS1L
gene id: 93934:BRMS1L
uniprot id: A0A8C2UBZ7
names: Subcellular Location Annotation
messages: Nucleus

93934:POLR3A
gene id: 93934:POLR3A
uniprot id: A0A8C2TF52
uniprot id: A0A8C2TIK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

93934:SEPTIN9
gene id: 93934:SEPTIN9
uniprot id: A0A8C2UFL2
uniprot id: A0A8C2YHB1
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

93934:MME
gene id: 93934:MME
uniprot id: A0A8C2U3K6
names: Cofactor
messages: Binds 1 zinc ion per subunit.

93934:CASQ2
gene id: 93934:CASQ2
uniprot id: A0A8C2U371
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calsequestrin family.
messages: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle.
messages: Sarcoplasmic reticulum lumen

93934:ATP1A1
gene id: 93934:ATP1A1
uniprot id: A0A8C2U362
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane

93934:ULK3
gene id: 93934:ULK3
uniprot id: A0A8C2T708
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:SPP1
gene id: 93934:SPP1
uniprot id: Q9I832
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the osteopontin family.
messages: Secreted

93934:VPS18
gene id: 93934:VPS18
uniprot id: A0A8C2TUJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

93934:GUCY1B1
gene id: 93934:GUCY1B1
uniprot id: A0A8C2SNL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

93934:LOC107325545
gene id: 93934:LOC107325545
uniprot id: A0A8C2TGG8
names: Similarity
messages: Belongs to the perilipin family.

93934:SGK1
gene id: 93934:SGK1
uniprot id: A0A8C2T997
uniprot id: A0A8C2TCJ7
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:GPNMB
gene id: 93934:GPNMB
uniprot id: Q90372
names: Developmental Stage
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the PMEL/NMB family.
messages: Could be involved in melanogenesis.
messages: Melanocyte-specific, restricted to the pigmented layer of the retina and the epidermis.
messages: Membrane
messages: Transcriptionally regulated by MYC in the transdifferentiation of embryo pigmented epithelial cells. Expression precedes melanization.

93934:TRIM32
gene id: 93934:TRIM32
uniprot id: A0A8C2UB56
names: Similarity
messages: Belongs to the TRIM/RBCC family.

93934:MAP2K6
gene id: 93934:MAP2K6
uniprot id: A0A8C2UJR9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:NUP88
gene id: 93934:NUP88
uniprot id: A0A8C2Y9Q3
names: Subcellular Location Annotation
messages: nuclear pore complex

93934:ELOVL5
gene id: 93934:ELOVL5
uniprot id: A0A8C2Y8U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL5 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: dendrite

93934:GALM
gene id: 93934:GALM
uniprot id: A0A8C2SXF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aldose epimerase family.
messages: Monomer.
messages: Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism.

93934:LOC107324369
gene id: 93934:LOC107324369
uniprot id: A0A8C2YCU1
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:BCL2L14
gene id: 93934:BCL2L14
uniprot id: A0A8C2TX67
names: Similarity
messages: Belongs to the Bcl-2 family.

93934:TCP11L2
gene id: 93934:TCP11L2
uniprot id: A0A8C2U430
names: Similarity
messages: Belongs to the TCP11 family.

93934:ANKRD17
gene id: 93934:ANKRD17
uniprot id: A0A8C2SRL3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:LOC107317186
gene id: 93934:LOC107317186
uniprot id: A0A8C2UFC7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family.

93934:RPS23
gene id: 93934:RPS23
uniprot id: A0A8C2SMH8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Component of the 40S small ribosomal subunit.
messages: Rough endoplasmic reticulum

93934:OLFM4
gene id: 93934:OLFM4
uniprot id: A0A8C2U8X6
uniprot id: A0A8C2UE19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CREB3L2
gene id: 93934:CREB3L2
uniprot id: A0A8C2UB44
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bZIP family. ATF subfamily.
messages: Binds DNA as a dimer.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

93934:TJP3
gene id: 93934:TJP3
uniprot id: A0A8C2T158
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

93934:LOC107314689
gene id: 93934:LOC107314689
uniprot id: A0A8C2TJQ9
names: Function
names: Similarity
messages: Belongs to the SAA family.
messages: Major acute phase reactant. Apolipoprotein of the HDL complex.

93934:RDH10
gene id: 93934:RDH10
uniprot id: A0A8C2TKB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

93934:FAH
gene id: 93934:FAH
uniprot id: A0A8C2YH28
names: Similarity
messages: Belongs to the FAH family.

93934:ARHGDIB
gene id: 93934:ARHGDIB
uniprot id: A0A8C2T7Z7
names: Similarity
messages: Belongs to the Rho GDI family.

93934:MEP1A
gene id: 93934:MEP1A
uniprot id: A0A8C2SR14
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:RBKS
gene id: 93934:RBKS
uniprot id: A0A8C2YAF3
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

93934:TERF1
gene id: 93934:TERF1
uniprot id: A0A8C2TKV7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Binds the telomeric double-stranded 5'-TTAGGG-3' repeat.
messages: Homodimer.
messages: Nucleus

93934:PRPF38A
gene id: 93934:PRPF38A
uniprot id: A0A8C2TIR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRP38 family.
messages: Component of the spliceosome B complex.
messages: Involved in pre-mRNA splicing as a component of the spliceosome.
messages: Nucleus

93934:LOC107323889
gene id: 93934:LOC107323889
uniprot id: A0A8C2Y7B8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:POFUT1
gene id: 93934:POFUT1
uniprot id: A0A8C2SY80
names: Similarity
messages: Belongs to the glycosyltransferase 65 family.

93934:LOC107316901
gene id: 93934:LOC107316901
uniprot id: A0A8C2TQY3
names: Similarity
messages: Belongs to the apolipoprotein L family.

93934:PPP3R1
gene id: 93934:PPP3R1
uniprot id: A0A8C2TH23
names: Similarity
messages: Belongs to the calcineurin regulatory subunit family.

93934:ANO8
gene id: 93934:ANO8
uniprot id: A0A8C2TG70
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:FARSB
gene id: 93934:FARSB
uniprot id: A0A8C2T2J7
names: Similarity
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.

93934:SERPINE2
gene id: 93934:SERPINE2
uniprot id: A0A8C2SZM4
uniprot id: A0A8C2T1H0
names: Similarity
messages: Belongs to the serpin family.

93934:PLEKHO1
gene id: 93934:PLEKHO1
uniprot id: A0A8C2TT25
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:PSMD1
gene id: 93934:PSMD1
uniprot id: A0A8C2TPK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S1 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP).
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

93934:PKNOX2
gene id: 93934:PKNOX2
uniprot id: A0A8C2SZ09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

93934:SIX4
gene id: 93934:SIX4
uniprot id: A0A8C2T1R0
names: Subcellular Location Annotation
messages: Nucleus

93934:COPS8
gene id: 93934:COPS8
uniprot id: A0A8C2YCL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN8 family.
messages: Cytoplasm
messages: Nucleus

93934:WNT6
gene id: 93934:WNT6
uniprot id: A0A8C2TQG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:CLCN1
gene id: 93934:CLCN1
uniprot id: A0A8C2U263
names: Subcellular Location Annotation
messages: Membrane

93934:ABCC2
gene id: 93934:ABCC2
uniprot id: A0A8C2UAF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Melanosome membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: extracellular exosome
messages: multivesicular body membrane

93934:PI4K2A
gene id: 93934:PI4K2A
uniprot id: A0A8C2UAJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family. Type II PI4K subfamily.
messages: Membrane

93934:ADAMTS18
gene id: 93934:ADAMTS18
uniprot id: A0A8C2TVI6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:TEKT3
gene id: 93934:TEKT3
uniprot id: A0A8C2UE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

93934:LOC107313501
gene id: 93934:LOC107313501
uniprot id: A0A8C2SP37
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

93934:ADORA2A
gene id: 93934:ADORA2A
uniprot id: A0A8C2TB37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

93934:PDE9A
gene id: 93934:PDE9A
uniprot id: A0A8C2T891
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:SAR1B
gene id: 93934:SAR1B
uniprot id: A0A8C2SZP6
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.

93934:NCEH1
gene id: 93934:NCEH1
uniprot id: A0A8C2TRA3
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

93934:CA3
gene id: 93934:CA3
uniprot id: A0A8C2SKG3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cytoplasm
messages: Reversible hydration of carbon dioxide.

93934:MRPL23
gene id: 93934:MRPL23
uniprot id: A0A8C2U6X9
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

93934:SKP1
gene id: 93934:SKP1
uniprot id: A0A8C2Y742
names: Function
names: Similarity
messages: Belongs to the SKP1 family.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1.

93934:MRPS18A
gene id: 93934:MRPS18A
uniprot id: A0A8C2TJH3
names: Subcellular Location Annotation
messages: Mitochondrion

93934:NEK7
gene id: 93934:NEK7
uniprot id: A0A8C2UGB2
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:SOST
gene id: 93934:SOST
uniprot id: A0A8C2U9K8
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the sclerostin family.
messages: Interacts with LRP4 (via the extracellular domain); the interaction facilitates the inhibition of Wnt signaling. Interacts with LRP5 (via the first two YWTD-EGF repeat domains); the interaction inhibits Wnt-mediated signaling. Interacts with LRP6.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

93934:DTD1
gene id: 93934:DTD1
uniprot id: A0A8C2SVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

93934:LOC107305817
gene id: 93934:LOC107305817
uniprot id: A0A8C2Y7E2
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

93934:ALDH9A1
gene id: 93934:ALDH9A1
uniprot id: A0A8C2UJE9
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93934:SLU7
gene id: 93934:SLU7
uniprot id: A0A8C2T8F4
uniprot id: A0A8C2T905
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

93934:MLF2
gene id: 93934:MLF2
uniprot id: A0A8C2TZ72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

93934:COPG1
gene id: 93934:COPG1
uniprot id: A0A8C2TQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

93934:PSMC1
gene id: 93934:PSMC1
uniprot id: A0A8C2SPW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

93934:NT5DC2
gene id: 93934:NT5DC2
uniprot id: A0A8C2SUP2
names: Cofactor
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.
messages: Binds 1 Mg(2+) ion per subunit.

93934:MMP23B
gene id: 93934:MMP23B
uniprot id: A0A8C2TCQ3
names: Caution
names: Similarity
messages: Belongs to the peptidase M10A family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ERBB2
gene id: 93934:ERBB2
uniprot id: A0A8C2SQA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

93934:LOC107315364
gene id: 93934:LOC107315364
uniprot id: A0A8C2SQN5
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:BLVRA
gene id: 93934:BLVRA
uniprot id: A0A8C2Y4V7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Gfo/Idh/MocA family. Biliverdin reductase subfamily.
messages: Monomer.
messages: Reduces the gamma-methene bridge of the open tetrapyrrole, biliverdin IX alpha, to bilirubin with the concomitant oxidation of a NADH or NADPH cofactor.
messages: cytosol

93934:ZHX2
gene id: 93934:ZHX2
uniprot id: A0A8C2SZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

93934:C1S
gene id: 93934:C1S
uniprot id: A0A8C2U1J3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107318181
gene id: 93934:LOC107318181
uniprot id: A0A8C2TNT7
names: Similarity
messages: Belongs to the DNA photolyase class-2 family.

93934:RTN4
gene id: 93934:RTN4
uniprot id: A0A8C2TXH5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LMNB1
gene id: 93934:LMNB1
uniprot id: A0A8C2YBX4
names: Similarity
messages: Belongs to the intermediate filament family.

93934:HEATR5A
gene id: 93934:HEATR5A
uniprot id: A0A8C2U1L2
uniprot id: A0A8C2U6V0
names: Similarity
messages: Belongs to the HEATR5 family.

93934:TMSB15B
gene id: 93934:TMSB15B
uniprot id: Q9DET5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thymosin beta family.
messages: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization (By similarity).
messages: cytoskeleton

93934:KEF80 p05
gene id: 93934:KEF80_p05
uniprot id: Q8SEW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4L family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.
messages: Membrane
messages: Mitochondrion inner membrane

93934:ZNF592
gene id: 93934:ZNF592
uniprot id: A0A8C2SLH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

93934:ATP6V0A1
gene id: 93934:ATP6V0A1
uniprot id: A0A8C2SY58
uniprot id: A0A8C2SYU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

93934:SIX1
gene id: 93934:SIX1
uniprot id: A0A8C2Y7J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Cytoplasm
messages: Nucleus

93934:MOS
gene id: 93934:MOS
uniprot id: A0A8C2TFI0
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:GBA2
gene id: 93934:GBA2
uniprot id: A0A8C2T1M9
names: Function
names: Similarity
messages: Belongs to the non-lysosomal glucosylceramidase family.
messages: Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide.

93934:LOC107318287
gene id: 93934:LOC107318287
uniprot id: A0A8C2U276
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Cell projection
messages: Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Perikaryon
messages: Transport is mediated via a series of conformation changes, switching between a conformation where the substrate-binding cavity is accessible from the outside, and a another conformation where it is accessible from the cytoplasm.

93934:SPSB1
gene id: 93934:SPSB1
uniprot id: A0A8C2TGS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

93934:ELF1
gene id: 93934:ELF1
uniprot id: A0A8C2UAW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:SLCO2B1
gene id: 93934:SLCO2B1
uniprot id: A0A8C2T4C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

93934:RIBC2
gene id: 93934:RIBC2
uniprot id: A0A8C2TY18
names: Similarity
messages: Belongs to the RIB43A family.

93934:ODF2L
gene id: 93934:ODF2L
uniprot id: A0A8C2T745
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ODF2 family.
messages: centrosome

93934:NAE1
gene id: 93934:NAE1
uniprot id: A0A8C2TT45
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
messages: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M.

93934:FITM2
gene id: 93934:FITM2
uniprot id: A0A8C2SMC6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ACAD11
gene id: 93934:ACAD11
uniprot id: A0A8C2SWH0
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93934:PHKG1
gene id: 93934:PHKG1
uniprot id: A0A8C2TFE5
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily.
messages: Hexadecamer of 4 heterotetramers, each composed of alpha, beta, gamma, and delta subunits. Alpha (PHKA1 or PHKA2) and beta (PHKB) are regulatory subunits, gamma (PHKG1 or PHKG2) is the catalytic subunit, and delta is calmodulin.

93934:P2RY1
gene id: 93934:P2RY1
uniprot id: A0A8C2U8V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:MACO1
gene id: 93934:MACO1
uniprot id: A0A8C2TXN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the macoilin family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: Rough endoplasmic reticulum membrane

93934:VPS45
gene id: 93934:VPS45
uniprot id: A0A8C2TPU5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

93934:PALMD
gene id: 93934:PALMD
uniprot id: A0A8C2SKI2
names: Similarity
messages: Belongs to the paralemmin family.

93934:NT5DC1
gene id: 93934:NT5DC1
uniprot id: A0A8C2TC71
names: Similarity
messages: Belongs to the 5'(3')-deoxyribonucleotidase family.

93934:PTGS1
gene id: 93934:PTGS1
uniprot id: A0A8C2TIH6
names: Caution
names: Similarity
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ESCO1
gene id: 93934:ESCO1
uniprot id: A0A8C2Y9N8
names: Subcellular Location Annotation
messages: Nucleus

93934:BMP10
gene id: 93934:BMP10
uniprot id: A0A8C2TIG0
names: Similarity
messages: Belongs to the TGF-beta family.

93934:DESI1
gene id: 93934:DESI1
uniprot id: A0A8C2T9K8
names: Similarity
messages: Belongs to the DeSI family.

93934:LOC107308493
gene id: 93934:LOC107308493
uniprot id: A0A8C2SVF9
names: Subcellular Location Annotation
messages: Membrane

93934:CYGB
gene id: 93934:CYGB
uniprot id: A0A8C2UEJ8
names: Similarity
messages: Belongs to the globin family.

93934:UCN
gene id: 93934:UCN
uniprot id: A0A8C2TMM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

93934:RGS9BP
gene id: 93934:RGS9BP
uniprot id: A0A8C2TUU3
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

93934:HPS5
gene id: 93934:HPS5
uniprot id: A0A8C2TGM5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HPS5 family.
messages: Component of the biogenesis of lysosome-related organelles complex-2 (or BLOC2) composed of HPS3, HPS5 and HPS6.
messages: May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules.
messages: cytosol

93934:GFRA4
gene id: 93934:GFRA4
uniprot id: A0A8C2T593
names: Similarity
messages: Belongs to the GDNFR family.

93934:TSC22D1
gene id: 93934:TSC22D1
uniprot id: A0A8C2U921
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

93934:UBA6
gene id: 93934:UBA6
uniprot id: A0A8C2Y5D4
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

93934:UPF1
gene id: 93934:UPF1
uniprot id: A0A8C2TIZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

93934:MTF2
gene id: 93934:MTF2
uniprot id: A0A8C2T7B9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Polycomblike family.
messages: Nucleus

93934:EFHC2
gene id: 93934:EFHC2
uniprot id: A0A8C2TQJ2
names: Subcellular Location Annotation
messages: cilium axoneme

93934:EIF4G1
gene id: 93934:EIF4G1
uniprot id: A0A8C2TPZ4
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4G family.

93934:UCHL3
gene id: 93934:UCHL3
uniprot id: A0A8C2UDI5
names: Similarity
messages: Belongs to the peptidase C12 family.

93934:CRY2
gene id: 93934:CRY2
uniprot id: A0A8C2TUF9
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

93934:PRDX1
gene id: 93934:PRDX1
uniprot id: A0A8C2TEM6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

93934:GALNT13
gene id: 93934:GALNT13
uniprot id: A0A8C2UDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:COPS7A
gene id: 93934:COPS7A
uniprot id: A0A8C2TZ33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN7/EIF3M family. CSN7 subfamily.
messages: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
messages: Cytoplasm
messages: Nucleus

93934:DYM
gene id: 93934:DYM
uniprot id: A0A8C2T1C3
uniprot id: A0A8C2Y779
names: Similarity
messages: Belongs to the dymeclin family.

93934:LOC107324742
gene id: 93934:LOC107324742
uniprot id: A0A8C2TA50
names: Subcellular Location Annotation
messages: Membrane

93934:ARMC8
gene id: 93934:ARMC8
uniprot id: A0A8C2U5K8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:HOXA11
gene id: 93934:HOXA11
uniprot id: A0A8C2TMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

93934:FGF4
gene id: 93934:FGF4
uniprot id: A0A8C2U6N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

93934:DSE
gene id: 93934:DSE
uniprot id: A0A8C2TF89
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

93934:SLC6A6
gene id: 93934:SLC6A6
uniprot id: A0A8C2TWK0
uniprot id: A0A8C2U1Y4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A6 subfamily.
messages: Cell membrane
messages: Membrane

93934:BMP5
gene id: 93934:BMP5
uniprot id: A0A8C2T7G5
names: Similarity
messages: Belongs to the TGF-beta family.

93934:IMP3
gene id: 93934:IMP3
uniprot id: A0A8C2Y609
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

93934:GTF2B
gene id: 93934:GTF2B
uniprot id: A0A8C2T6X2
names: Similarity
messages: Belongs to the TFIIB family.

93934:MC3R
gene id: 93934:MC3R
uniprot id: A0A8C2T609
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane

93934:CPLX2
gene id: 93934:CPLX2
uniprot id: A0A8C2TJ62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

93934:PPARGC1A
gene id: 93934:PPARGC1A
uniprot id: A0A8C2U412
names: Subcellular Location Annotation
messages: PML body

93934:MARS1
gene id: 93934:MARS1
uniprot id: A0A8C2SXV3
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:ZC3H14
gene id: 93934:ZC3H14
uniprot id: A0A8C2Y4W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZC3H14 family.
messages: Involved in poly(A) tail length control in neuronal cells. Binds the polyadenosine RNA oligonucleotides.
messages: Nucleus speckle

93934:SOX11
gene id: 93934:SOX11
uniprot id: A0A8C2Y9G3
names: Subcellular Location Annotation
messages: Nucleus

93934:MRPS7
gene id: 93934:MRPS7
uniprot id: A0A8C2YHY9
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

93934:SLC35C2
gene id: 93934:SLC35C2
uniprot id: A0A8C2T415
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107324692
gene id: 93934:LOC107324692
uniprot id: A0A8C2T9S9
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

93934:PAPPA
gene id: 93934:PAPPA
uniprot id: A0A8C2U8T5
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:STAT3
gene id: 93934:STAT3
uniprot id: A0A8C2SWX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

93934:NCOA1
gene id: 93934:NCOA1
uniprot id: A0A8C2TMG6
uniprot id: A0A8C2TQB6
uniprot id: Q8UVH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

93934:KIF18A
gene id: 93934:KIF18A
uniprot id: A0A8C2TXH1
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:MITF
gene id: 93934:MITF
uniprot id: A0A8C2U3M6
uniprot id: A0A8C2YFJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

93934:TUBGCP3
gene id: 93934:TUBGCP3
uniprot id: A0A8C2TZA8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

93934:DRAM2
gene id: 93934:DRAM2
uniprot id: A0A8C2TBU8
names: Subcellular Location Annotation
messages: Membrane

93934:HNF1A
gene id: 93934:HNF1A
uniprot id: A0A8C2TSU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HNF1 homeobox family.
messages: Nucleus

93934:RIPK2
gene id: 93934:RIPK2
uniprot id: A0A8C2SKJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.
messages: Cytoplasm
messages: Found in a signaling complex consisting of at least ARHGEF2, NOD2 and RIPK2.
messages: Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.

93934:ACTA1
gene id: 93934:ACTA1
uniprot id: A0A8C2SXY8
names: Similarity
messages: Belongs to the actin family.

93934:CASP7
gene id: 93934:CASP7
uniprot id: A0A8C2UC52
names: Similarity
messages: Belongs to the peptidase C14A family.

93934:PAN2
gene id: 93934:PAN2
uniprot id: A0A8C2SW91
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: P-body
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

93934:GADD45B
gene id: 93934:GADD45B
uniprot id: A0A8C2YAR4
names: Similarity
messages: Belongs to the GADD45 family.

93934:MED9
gene id: 93934:MED9
uniprot id: A0A8C2SQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:RAMP1
gene id: 93934:RAMP1
uniprot id: A0A8C2TR33
names: Similarity
messages: Belongs to the RAMP family.

93934:PRKD1
gene id: 93934:PRKD1
uniprot id: A0A8C2U3P7
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by DAG and phorbol esters.
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
messages: Cytoplasm
messages: Membrane

93934:GSK3B
gene id: 93934:GSK3B
uniprot id: A0A8C2U4N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.
messages: Cytoplasm
messages: Nucleus

93934:TGM4
gene id: 93934:TGM4
uniprot id: A0A8C2SXB3
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

93934:CNOT6
gene id: 93934:CNOT6
uniprot id: A0A8C2SXZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

93934:CHSY3
gene id: 93934:CHSY3
uniprot id: A0A8C2TB19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

93934:TRAF6
gene id: 93934:TRAF6
uniprot id: A0A8C2THP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family. A subfamily.
messages: Lipid droplet
messages: Nucleus
messages: cell cortex

93934:SIGMAR1
gene id: 93934:SIGMAR1
uniprot id: A0A8C2Y7G5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERG2 family.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum membrane
messages: Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Regulates calcium efflux at the endoplasmic reticulum.
messages: Homotrimer.
messages: Membrane
messages: Nucleus envelope
messages: Nucleus inner membrane
messages: Nucleus outer membrane
messages: The C-terminal helices form a flat, hydrophobic surface that is probably tightly associated with the cytosolic surface of the endoplasmic reticulum membrane.
messages: Vesicle

93934:SDHA
gene id: 93934:SDHA
uniprot id: A0A8C2TTJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

93934:GABRG1
gene id: 93934:GABRG1
uniprot id: A0A8C2YET0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:FAM124A
gene id: 93934:FAM124A
uniprot id: A0A8C2UB97
names: Similarity
messages: Belongs to the FAM124 family.

93934:LOC107311682
gene id: 93934:LOC107311682
uniprot id: A0A8C2TCH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

93934:ADNP
gene id: 93934:ADNP
uniprot id: A0A8C2T3Q5
uniprot id: A0A8C2T7F2
names: Subcellular Location Annotation
messages: Nucleus

93934:MAB21L3
gene id: 93934:MAB21L3
uniprot id: A0A8C2U105
names: Similarity
messages: Belongs to the mab-21 family.

93934:LOC107309562
gene id: 93934:LOC107309562
uniprot id: A0A8C2TVD4
names: Similarity
messages: Belongs to the serpin family.

93934:SKIL
gene id: 93934:SKIL
uniprot id: A0A8C2U2V1
uniprot id: A0A8C2U7M4
names: Similarity
messages: Belongs to the SKI family.

93934:FGF7
gene id: 93934:FGF7
uniprot id: A0A8C2UC95
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:FTCD
gene id: 93934:FTCD
uniprot id: A0A8C2TLF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds and promotes bundling of vimentin filaments originating from the Golgi.
messages: Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.
messages: Golgi apparatus
messages: Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.
messages: In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.
messages: In the N-terminal section; belongs to the formiminotransferase family.
messages: centriole

93934:MRPS10
gene id: 93934:MRPS10
uniprot id: A0A8C2T5L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Mitochondrion

93934:LOC107324394
gene id: 93934:LOC107324394
uniprot id: A0A8C2TQ66
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:HMOX2
gene id: 93934:HMOX2
uniprot id: A0A8C2YEH2
names: Similarity
messages: Belongs to the heme oxygenase family.

93934:HMGA2
gene id: 93934:HMGA2
uniprot id: A0A8C2TVA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

93934:SFRP2
gene id: 93934:SFRP2
uniprot id: A0A8C2SQ06
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:HOXA9
gene id: 93934:HOXA9
uniprot id: A0A8C2TKQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

93934:CDC42EP3
gene id: 93934:CDC42EP3
uniprot id: A0A8C2TMN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORG/CEP family.
messages: Endomembrane system

93934:CAVIN2
gene id: 93934:CAVIN2
uniprot id: A0A8C2TDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

93934:CEMIP2
gene id: 93934:CEMIP2
uniprot id: A0A8C2T5P2
uniprot id: A0A8C2T6A1
names: Similarity
messages: Belongs to the CEMIP family.

93934:FAM13B
gene id: 93934:FAM13B
uniprot id: A0A8C2SYE4
uniprot id: A0A8C2T0Y5
names: Similarity
messages: Belongs to the FAM13 family.

93934:AK4
gene id: 93934:AK4
uniprot id: A0A8C2TV20
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP/ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP/ATP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity.
messages: Mitochondrion matrix
messages: Monomer.

93934:LOC107317036
gene id: 93934:LOC107317036
uniprot id: A0A8C2UF54
names: Subunit
messages: Monomer.

93934:GPI
gene id: 93934:GPI
uniprot id: A0A8C2TWE2
names: Similarity
messages: Belongs to the GPI family.

93934:LOC107321369
gene id: 93934:LOC107321369
uniprot id: A0A8C2YCC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:PI4KB
gene id: 93934:PI4KB
uniprot id: A0A8C2TUC8
uniprot id: A0A8C2TUD6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

93934:EXOC1
gene id: 93934:EXOC1
uniprot id: A0A8C2TH97
names: Similarity
messages: Belongs to the SEC3 family.

93934:LOC107314340
gene id: 93934:LOC107314340
uniprot id: A0A8C2TWZ3
names: Similarity
messages: Belongs to the TCP11 family.

93934:RPS15A
gene id: 93934:RPS15A
uniprot id: A0A8C2TXD4
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: Component of the 40S ribosomal subunit.

93934:RBM22
gene id: 93934:RBM22
uniprot id: A0A8C2T558
names: Similarity
messages: Belongs to the SLT11 family.

93934:DPYSL2
gene id: 93934:DPYSL2
uniprot id: A0A8C2TIG5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

93934:PDXK
gene id: 93934:PDXK
uniprot id: A0A8C2TAP4
names: Similarity
messages: Belongs to the pyridoxine kinase family.

93934:DPT
gene id: 93934:DPT
uniprot id: A0A8C2YF46
names: Similarity
messages: Belongs to the dermatopontin family.

93934:LOC107314384
gene id: 93934:LOC107314384
uniprot id: A0A8C2TZA5
names: Similarity
messages: Belongs to the actin family.

93934:HOXB5
gene id: 93934:HOXB5
uniprot id: A0A8C2U9Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:SV2C
gene id: 93934:SV2C
uniprot id: A0A8C2SP91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

93934:CASR
gene id: 93934:CASR
uniprot id: A0A8C2U2A3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:LOC107309565
gene id: 93934:LOC107309565
uniprot id: A0A8C2TVY7
names: Similarity
messages: Belongs to the serpin family.

93934:FAM114A2
gene id: 93934:FAM114A2
uniprot id: A0A8C2T3C5
names: Similarity
messages: Belongs to the FAM114 family.

93934:NLK
gene id: 93934:NLK
uniprot id: A0A8C2U657
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

93934:ARHGEF11
gene id: 93934:ARHGEF11
uniprot id: A0A8C2TSH4
uniprot id: A0A8C2YCW5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane

93934:FRAT2
gene id: 93934:FRAT2
uniprot id: A0A8C2SP36
names: Similarity
messages: Belongs to the GSK-3-binding protein family.

93934:LOC107324901
gene id: 93934:LOC107324901
uniprot id: A0A8C2U9N0
names: Similarity
messages: Belongs to the peptidase A1 family.

93934:EIF3I
gene id: 93934:EIF3I
uniprot id: A0A8C2SMP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

93934:TCTEX1D4
gene id: 93934:TCTEX1D4
uniprot id: A0A8C2YA63
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

93934:IFT57
gene id: 93934:IFT57
uniprot id: A0A8C2U6L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IFT57 family.
messages: cilium basal body

93934:TMX2
gene id: 93934:TMX2
uniprot id: A0A8C2YF90
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

93934:EIF4H
gene id: 93934:EIF4H
uniprot id: A0A8C2T8Q2
names: Function
names: Subcellular Location Annotation
messages: Stimulates the RNA helicase activity of EIF4A in the translation initiation complex. Binds weakly mRNA.
messages: perinuclear region

93934:LOC107315833
gene id: 93934:LOC107315833
uniprot id: A0A8C2TF69
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

93934:NRG2
gene id: 93934:NRG2
uniprot id: A0A8C2TK47
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:RRM1
gene id: 93934:RRM1
uniprot id: A0A8C2SZ73
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

93934:SEZ6L
gene id: 93934:SEZ6L
uniprot id: A0A8C2T7W4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:DLGAP4
gene id: 93934:DLGAP4
uniprot id: A0A8C2UBX9
names: Similarity
messages: Belongs to the SAPAP family.

93934:PNPLA7
gene id: 93934:PNPLA7
uniprot id: A0A8C2U5R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:CDK7
gene id: 93934:CDK7
uniprot id: A0A8C2T647
uniprot id: A0A8C2T6G8
uniprot id: A0A8C2T700
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

93934:SELENOS
gene id: 93934:SELENOS
uniprot id: A0A8C2YHB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenoprotein S family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:STX16
gene id: 93934:STX16
uniprot id: A0A8C2T5V0
names: Similarity
messages: Belongs to the syntaxin family.

93934:PPP2R5C
gene id: 93934:PPP2R5C
uniprot id: A0A8C2STM5
uniprot id: A0A8C2SU44
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

93934:NRDC
gene id: 93934:NRDC
uniprot id: A0A8C2TN73
names: Similarity
messages: Belongs to the peptidase M16 family.

93934:MAFG
gene id: 93934:MAFG
uniprot id: A0A8C2UGA2
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

93934:DNER
gene id: 93934:DNER
uniprot id: A0A8C2T777
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LBX1
gene id: 93934:LBX1
uniprot id: A0A8C2YGT7
names: Subcellular Location Annotation
messages: Nucleus

93934:CLDN5
gene id: 93934:CLDN5
uniprot id: A0A8C2YG68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:MAPRE2
gene id: 93934:MAPRE2
uniprot id: A0A8C2TC65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

93934:LOC107322290
gene id: 93934:LOC107322290
uniprot id: A0A8C2UEB8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

93934:LOC107316860
gene id: 93934:LOC107316860
uniprot id: A0A8C2TS13
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:LOC107320417
gene id: 93934:LOC107320417
uniprot id: A0A8C2U3K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:SYS1
gene id: 93934:SYS1
uniprot id: A0A8C2UF00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYS1 family.
messages: Golgi apparatus membrane
messages: Interacts with ARFRP1.
messages: Involved in protein trafficking. May serve as a receptor for ARFRP1.
messages: Membrane

93934:LOC107314585
gene id: 93934:LOC107314585
uniprot id: A0A8C2UAC0
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

93934:TTC25
gene id: 93934:TTC25
uniprot id: A0A8C2SYK6
names: Subcellular Location Annotation
messages: cilium axoneme

93934:ITGB8
gene id: 93934:ITGB8
uniprot id: A0A8C2TIE5
uniprot id: A0A8C2TNJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

93934:COPB2
gene id: 93934:COPB2
uniprot id: A0A8C2T0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat COPB2 family.
messages: COPI-coated vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
messages: This coatomer complex protein, essential for Golgi budding and vesicular trafficking, is a selective binding protein (RACK) for protein kinase C, epsilon type. It binds to Golgi membranes in a GTP-dependent manner.

93934:USP13
gene id: 93934:USP13
uniprot id: A0A8C2TV01
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:PRKG1
gene id: 93934:PRKG1
uniprot id: A0A8C2TM46
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

93934:CMTM8
gene id: 93934:CMTM8
uniprot id: A0A8C2TLU0
names: Subcellular Location Annotation
messages: Membrane

93934:MEF2A
gene id: 93934:MEF2A
uniprot id: A0A8C2UHL7
names: Subcellular Location Annotation
messages: Nucleus

93934:SNAPIN
gene id: 93934:SNAPIN
uniprot id: A0A8C2TUI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAPIN family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling.
messages: synaptic vesicle membrane

93934:COQ8A
gene id: 93934:COQ8A
uniprot id: A0A8C2Y5K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.
messages: Membrane
messages: Mitochondrion

93934:CHRNA7
gene id: 93934:CHRNA7
uniprot id: A0A8C2YC15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:PM20D2
gene id: 93934:PM20D2
uniprot id: A0A8C2Y6H3
names: Similarity
messages: Belongs to the peptidase M20A family.

93934:LOC107312371
gene id: 93934:LOC107312371
uniprot id: A0A8C2T9V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

93934:ELP1
gene id: 93934:ELP1
uniprot id: A0A8C2STD5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

93934:CSNK2A1
gene id: 93934:CSNK2A1
uniprot id: A0A8C2SZP3
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:LOC107312604
gene id: 93934:LOC107312604
uniprot id: A0A8C2SSX0
uniprot id: A0A8C2Y650
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:APOA1
gene id: 93934:APOA1
uniprot id: P32918
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the apolipoprotein A1/A4/E family.
messages: Major protein of VLDL, HDL, LDL and in chylomicrons. Expressed in a number of tissues including liver, small intestine, lung, kidney, heart and muscle with highest expression in liver and small intestine.
messages: Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT).
messages: Secreted

93934:CNDP2
gene id: 93934:CNDP2
uniprot id: A0A8C2T3S6
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20A family.
messages: Binds 2 manganese ions per subunit.

93934:MAPKAPK2
gene id: 93934:MAPKAPK2
uniprot id: A0A8C2TTL0
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:LOC107324427
gene id: 93934:LOC107324427
uniprot id: A0A8C2TV61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus
messages: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity.

93934:LOC107310176
gene id: 93934:LOC107310176
uniprot id: A0A8C2TDS1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:FAM20B
gene id: 93934:FAM20B
uniprot id: A0A8C2UK33
names: Similarity
messages: Belongs to the FAM20 family.

93934:MON2
gene id: 93934:MON2
uniprot id: A0A8C2TVE4
uniprot id: A0A8C2TXN5
names: Similarity
messages: Belongs to the MON2 family.

93934:TAF4B
gene id: 93934:TAF4B
uniprot id: A0A8C2TC80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Nucleus

93934:TOP1MT
gene id: 93934:TOP1MT
uniprot id: A0A8C2TJG6
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

93934:STXBP1
gene id: 93934:STXBP1
uniprot id: A0A8C2UEK5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

93934:TMEM30A
gene id: 93934:TMEM30A
uniprot id: A0A8C2T376
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC50/LEM3 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: secretory vesicle membrane

93934:DDX41
gene id: 93934:DDX41
uniprot id: A0A8C2YAB2
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX41 subfamily.

93934:CASC1
gene id: 93934:CASC1
uniprot id: A0A8C2STV2
names: Similarity
messages: Belongs to the DNAI7 family.

93934:GPC1
gene id: 93934:GPC1
uniprot id: A0A8C2TV84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.
messages: extracellular space

93934:ACTR1A
gene id: 93934:ACTR1A
uniprot id: A0A8C2UF64
names: Similarity
messages: Belongs to the actin family.

93934:VGLL2
gene id: 93934:VGLL2
uniprot id: A0A8C2T9R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vestigial family.
messages: Nucleus

93934:LSM14B
gene id: 93934:LSM14B
uniprot id: A0A8C2SRD3
uniprot id: A0A8C2SSX2
names: Similarity
messages: Belongs to the LSM14 family.

93934:TARS2
gene id: 93934:TARS2
uniprot id: A0A8C2TUE1
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

93934:CASP2
gene id: 93934:CASP2
uniprot id: A0A8C2TZH1
names: Similarity
messages: Belongs to the peptidase C14A family.

93934:GINS1
gene id: 93934:GINS1
uniprot id: A0A8C2SX12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Chromosome
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

93934:CACFD1
gene id: 93934:CACFD1
uniprot id: A0A8C2T4T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel flower family.
messages: Membrane

93934:ZHX3
gene id: 93934:ZHX3
uniprot id: A0A8C2UCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

93934:CFTR
gene id: 93934:CFTR
uniprot id: A0A8C2TMC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the ABC transporter superfamily. ABCC family. CFTR transporter (TC 3.A.1.202) subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
messages: Recycling endosome membrane

93934:MAL2
gene id: 93934:MAL2
uniprot id: A0A8C2Y7H5
names: Subcellular Location Annotation
messages: Membrane

93934:CRYBB2
gene id: 93934:CRYBB2
uniprot id: A0A8C2TAG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the beta/gamma-crystallin family.
messages: Crystallins are the dominant structural components of the vertebrate eye lens.
messages: Homo/heterodimer, or complexes of higher-order. The structure of beta-crystallin oligomers seems to be stabilized through interactions between the N-terminal arms.

93934:NAAA
gene id: 93934:NAAA
uniprot id: A0A8C2SPF5
names: Similarity
messages: Belongs to the acid ceramidase family.

93934:DUT
gene id: 93934:DUT
uniprot id: A0A8C2U9D4
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

93934:LOC107319120
gene id: 93934:LOC107319120
uniprot id: A0A8C2TNM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

93934:HYI
gene id: 93934:HYI
uniprot id: A0A8C2TEF9
names: Function
names: Similarity
messages: Belongs to the hyi family.
messages: Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde).

93934:MCEE
gene id: 93934:MCEE
uniprot id: A0A8C2TPK0
names: Similarity
messages: Belongs to the methylmalonyl-CoA epimerase family.

93934:MEGF10
gene id: 93934:MEGF10
uniprot id: A0A8C2TKM3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ERG
gene id: 93934:ERG
uniprot id: A0A8C2T899
uniprot id: A0A8C2TB79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:CDH5
gene id: 93934:CDH5
uniprot id: A0A8C2TUW4
uniprot id: A0A8C2YD82
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell junction
messages: Cell membrane
messages: Membrane

93934:HSD17B3
gene id: 93934:HSD17B3
uniprot id: A0A8C2TAT9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:GSS
gene id: 93934:GSS
uniprot id: A0A8C2UHV7
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

93934:CCN4
gene id: 93934:CCN4
uniprot id: A0A8C2TCW1
uniprot id: A0A8C2TFM8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:HNRNPH1
gene id: 93934:HNRNPH1
uniprot id: A0A8C2T2L1
uniprot id: A0A8C2Y772
names: Subcellular Location Annotation
messages: nucleoplasm

93934:KCNMB2
gene id: 93934:KCNMB2
uniprot id: A0A8C2TQN3
names: Subcellular Location Annotation
messages: Membrane

93934:PDC
gene id: 93934:PDC
uniprot id: A0A8C2UH57
names: Similarity
messages: Belongs to the phosducin family.

93934:FGA
gene id: 93934:FGA
uniprot id: A0A8C2Y4Z5
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

93934:MBTPS1
gene id: 93934:MBTPS1
uniprot id: A0A8C2Y542
names: Similarity
messages: Belongs to the peptidase S8 family.

93934:PTHLH
gene id: 93934:PTHLH
uniprot id: A0A8C2YE95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: Secreted

93934:FABP1
gene id: 93934:FABP1
uniprot id: A0A8C2T237
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
messages: Cytoplasm
messages: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.

93934:LOC107322920
gene id: 93934:LOC107322920
uniprot id: A0A8C2UHJ4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:KEF80 p03
gene id: 93934:KEF80_p03
uniprot id: Q8SEW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion inner membrane

93934:NEK6
gene id: 93934:NEK6
uniprot id: A0A8C2TI32
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:HOXA1
gene id: 93934:HOXA1
uniprot id: A0A8C2TMP0
names: Subcellular Location Annotation
messages: Nucleus

93934:STEAP1
gene id: 93934:STEAP1
uniprot id: A0A8C2T170
names: Subcellular Location Annotation
messages: Membrane

93934:SUCLA2
gene id: 93934:SUCLA2
uniprot id: A0A8C2UCF3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for ATP.
messages: Mitochondrion

93934:SOX1
gene id: 93934:SOX1
uniprot id: A0A8C2TWG1
names: Subcellular Location Annotation
messages: Nucleus

93934:PROK1
gene id: 93934:PROK1
uniprot id: A0A8C2TC37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AVIT (prokineticin) family.
messages: Secreted

93934:CRYBA2
gene id: 93934:CRYBA2
uniprot id: A0A8C2TPT3
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

93934:BMPR1B
gene id: 93934:BMPR1B
uniprot id: A0A8C2T2I0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:ROR2
gene id: 93934:ROR2
uniprot id: A0A8C2TBF3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:KIF2B
gene id: 93934:KIF2B
uniprot id: A0A8C2UJ79
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:MIGA1
gene id: 93934:MIGA1
uniprot id: A0A8C2T7H3
uniprot id: A0A8C2TB84
names: Similarity
messages: Belongs to the mitoguardin family.

93934:MRGBP
gene id: 93934:MRGBP
uniprot id: A0A8C2STT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Nucleus

93934:SUGT1
gene id: 93934:SUGT1
uniprot id: A0A8C2U892
names: Similarity
messages: Belongs to the SGT1 family.

93934:SLC39A12
gene id: 93934:SLC39A12
uniprot id: A0A8C2SV38
uniprot id: A0A8C2SY42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Membrane

93934:DIPK2B
gene id: 93934:DIPK2B
uniprot id: A0A8C2T904
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Secreted

93934:RPS20
gene id: 93934:RPS20
uniprot id: A0A8C2YAK2
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Component of the 40S small ribosomal subunit.

93934:ADRA1B
gene id: 93934:ADRA1B
uniprot id: A0A8C2Y9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes.
messages: caveola

93934:FAM83F
gene id: 93934:FAM83F
uniprot id: A0A8C2TFS6
names: Similarity
messages: Belongs to the FAM83 family.

93934:L3MBTL1
gene id: 93934:L3MBTL1
uniprot id: A0A8C2U8B8
names: Subcellular Location Annotation
messages: Nucleus

93934:WEE1
gene id: 93934:WEE1
uniprot id: A0A8C2SV07
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

93934:DENND6B
gene id: 93934:DENND6B
uniprot id: A0A8C2Y4P6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND6 family.
messages: Endosome
messages: Recycling endosome

93934:CNTNAP1
gene id: 93934:CNTNAP1
uniprot id: A0A8C2SY74
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: paranodal septate junction

93934:RPL6
gene id: 93934:RPL6
uniprot id: A0A8C2T600
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

93934:PLCD1
gene id: 93934:PLCD1
uniprot id: A0A8C2TFD1
uniprot id: A0A8C2TKA5
names: Cofactor
messages: Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain.

93934:ARFGEF2
gene id: 93934:ARFGEF2
uniprot id: A0A8C2SUG4
names: Subcellular Location Annotation
messages: Golgi apparatus
messages: perinuclear region

93934:CDH13
gene id: 93934:CDH13
uniprot id: A0A8C2TSN3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: By contrast to classical cadherins, homodimerization in trans is not mediated by cadherin EC1 domain strand-swapping, but instead through a homophilic adhesive interface which joins two elongated EC1-EC2 domains through a region near their Ca2+-binding sites to form a tetrahedral, X-like shape.
messages: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
messages: Cell membrane
messages: Membrane

93934:LOC107320062
gene id: 93934:LOC107320062
uniprot id: A0A8C2UFG6
names: Similarity
messages: Belongs to the GDNFR family.

93934:CHL1
gene id: 93934:CHL1
uniprot id: A0A8C2U6Y2
uniprot id: A0A8C2U789
uniprot id: A0A8C2YFX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family.
messages: Membrane

93934:ATP6V1E1
gene id: 93934:ATP6V1E1
uniprot id: A0A8C2UAI3
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

93934:LOC107308616
gene id: 93934:LOC107308616
uniprot id: A0A8C2SZV6
names: Similarity
messages: Belongs to the folate receptor family.

93934:SNX6
gene id: 93934:SNX6
uniprot id: A0A8C2U1T4
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

93934:LPCAT2
gene id: 93934:LPCAT2
uniprot id: A0A8C2TKH6
uniprot id: A0A8C2TN76
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:INHBC
gene id: 93934:INHBC
uniprot id: A0A8C2SUP5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

93934:STOML1
gene id: 93934:STOML1
uniprot id: A0A8C2T5B0
names: Similarity
messages: Belongs to the band 7/mec-2 family.

93934:MSH3
gene id: 93934:MSH3
uniprot id: A0A8C2SN00
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

93934:DOP1A
gene id: 93934:DOP1A
uniprot id: A0A8C2SY97
names: Similarity
messages: Belongs to the dopey family.

93934:ANXA2
gene id: 93934:ANXA2
uniprot id: A0A8C2TPI2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: Membrane
messages: basement membrane

93934:SHMT1
gene id: 93934:SHMT1
uniprot id: A0A8C2SX20
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

93934:GPR50
gene id: 93934:GPR50
uniprot id: A0A8C2SME0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:CCNA2
gene id: 93934:CCNA2
uniprot id: A0A8C2SUH9
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

93934:CACNG1
gene id: 93934:CACNG1
uniprot id: A0A8C2UJW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Component of a calcium channel complex consisting of a pore-forming alpha subunit (CACNA1S) and the ancillary subunits CACNB1 or CACNB2, CACNG1 and CACNA2D1. The channel complex contains alpha, beta, gamma and delta subunits in a 1:1:1:1 ratio, i.e. it contains either CACNB1 or CACNB2.
messages: Membrane
messages: Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics.
messages: sarcolemma

93934:EIF4EBP2
gene id: 93934:EIF4EBP2
uniprot id: A0A8C2TGR8
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

93934:SLC10A2
gene id: 93934:SLC10A2
uniprot id: A0A8C2TYY6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Membrane
messages: Monomer and homodimer.

93934:ACTB
gene id: 93934:ACTB
uniprot id: A0A8C2SN21
names: Similarity
messages: Belongs to the actin family.

93934:ORAI2
gene id: 93934:ORAI2
uniprot id: A0A8C2YA70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

93934:TYRO3
gene id: 93934:TYRO3
uniprot id: A0A8C2TTU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Membrane

93934:GMDS
gene id: 93934:GMDS
uniprot id: A0A8C2TVZ7
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.

93934:MTMR8
gene id: 93934:MTMR8
uniprot id: A0A8C2U1V5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

93934:IPPK
gene id: 93934:IPPK
uniprot id: A0A8C2TLU7
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 2 family.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

93934:LUM
gene id: 93934:LUM
uniprot id: Q9DE67
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds keratan sulfate chains.
messages: Binds to laminin.
messages: extracellular matrix

93934:FAN1
gene id: 93934:FAN1
uniprot id: A0A8C2TKI2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAN1 family.
messages: Nuclease required for the repair of DNA interstrand cross-links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions.
messages: Nucleus

93934:SPTLC3
gene id: 93934:SPTLC3
uniprot id: A0A8C2SPI3
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

93934:FAM124B
gene id: 93934:FAM124B
uniprot id: A0A8C2T064
names: Similarity
messages: Belongs to the FAM124 family.

93934:TAF1D
gene id: 93934:TAF1D
uniprot id: A0A8C2SX66
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B, TAF1C and TAF1D. Interacts with UBTF.
messages: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
messages: Nucleus

93934:NEIL3
gene id: 93934:NEIL3
uniprot id: A0A8C2YA87
names: Similarity
messages: Belongs to the FPG family.

93934:ADI1
gene id: 93934:ADI1
uniprot id: A0A8C2TA63
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

93934:ASRGL1
gene id: 93934:ASRGL1
uniprot id: A0A8C2Y8A9
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

93934:ARF1
gene id: 93934:ARF1
uniprot id: A0A8C2THT5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

93934:UMODL1
gene id: 93934:UMODL1
uniprot id: A0A8C2T862
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ITGB6
gene id: 93934:ITGB6
uniprot id: A0A8C2TTG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

93934:XPNPEP1
gene id: 93934:XPNPEP1
uniprot id: A0A8C2U9F9
names: Similarity
messages: Belongs to the peptidase M24B family.

93934:MAPRE3
gene id: 93934:MAPRE3
uniprot id: A0A8C2TJR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: cytoskeleton

93934:DUS3L
gene id: 93934:DUS3L
uniprot id: A0A8C2TBT1
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.

93934:ARHGEF7
gene id: 93934:ARHGEF7
uniprot id: A0A8C2YE38
names: Subcellular Location Annotation
messages: lamellipodium

93934:SHOX2
gene id: 93934:SHOX2
uniprot id: A0A8C2U366
names: Subcellular Location Annotation
messages: Nucleus

93934:RAB3C
gene id: 93934:RAB3C
uniprot id: A0A8C2SRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

93934:CALHM2
gene id: 93934:CALHM2
uniprot id: A0A8C2UF20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

93934:ABAT
gene id: 93934:ABAT
uniprot id: A0A8C2TZZ1
names: Similarity
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer; disulfide-linked.

93934:UBAC1
gene id: 93934:UBAC1
uniprot id: A0A8C2T9R3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:CTNNA2
gene id: 93934:CTNNA2
uniprot id: A0A8C2T2N6
uniprot id: A0A8C2T2P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: Nucleus
messages: adherens junction
messages: axon
messages: cytoskeleton

93934:EPN3
gene id: 93934:EPN3
uniprot id: A0A8C2YHY1
names: Similarity
messages: Belongs to the epsin family.

93934:HS6ST2
gene id: 93934:HS6ST2
uniprot id: A0A8C2TZQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

93934:LOC107308206
gene id: 93934:LOC107308206
uniprot id: A0A8C2T8C3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:GAB3
gene id: 93934:GAB3
uniprot id: A0A8C2U595
names: Similarity
messages: Belongs to the GAB family.

93934:NDUFAF4
gene id: 93934:NDUFAF4
uniprot id: A0A8C2SKN9
names: Similarity
names: Subunit
messages: Belongs to the NDUFAF4 family.
messages: Binds calmodulin. Interacts with NDUFAF3.

93934:DHX15
gene id: 93934:DHX15
uniprot id: A0A8C2U944
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

93934:EMP1
gene id: 93934:EMP1
uniprot id: A0A8C2T8D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Membrane

93934:LOC107314906
gene id: 93934:LOC107314906
uniprot id: A0A8C2TVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

93934:RPIA
gene id: 93934:RPIA
uniprot id: A0A8C2T4H9
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

93934:TRHR
gene id: 93934:TRHR
uniprot id: A0A8C2SZR3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.

93934:LOC107315856
gene id: 93934:LOC107315856
uniprot id: A0A8C2U9E1
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:C4H4orf47
gene id: 93934:C4H4orf47
uniprot id: A0A8C2T504
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0602 family.
messages: centrosome

93934:METAP1
gene id: 93934:METAP1
uniprot id: A0A8C2T522
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).

93934:GTF2E1
gene id: 93934:GTF2E1
uniprot id: A0A8C2U4L8
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

93934:ENO1
gene id: 93934:ENO1
uniprot id: A0A8C2TIV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Cytoplasm

93934:TNFSF10
gene id: 93934:TNFSF10
uniprot id: A0A8C2TR38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

93934:GPATCH11
gene id: 93934:GPATCH11
uniprot id: A0A8C2YBP3
names: Similarity
messages: Belongs to the GPATCH11 family.

93934:ZC3HC1
gene id: 93934:ZC3HC1
uniprot id: A0A8C2SLB5
names: Subcellular Location Annotation
messages: Nucleus

93934:CMKLR1
gene id: 93934:CMKLR1
uniprot id: A0A8C2T4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Belongs to the chemokine-like receptor (CMKLR) family.
messages: Cell membrane
messages: Membrane

93934:LOC107309196
gene id: 93934:LOC107309196
uniprot id: A0A8C2TMV3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

93934:NT5E
gene id: 93934:NT5E
uniprot id: A0A8C2Y6V2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-nucleotidase family.
messages: Membrane

93934:RPL21
gene id: 93934:RPL21
uniprot id: A0A8C2Y561
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

93934:PELI1
gene id: 93934:PELI1
uniprot id: A0A8C2TJS0
names: Similarity
messages: Belongs to the pellino family.

93934:PSMA6
gene id: 93934:PSMA6
uniprot id: A0A8C2YF72
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

93934:LHX1
gene id: 93934:LHX1
uniprot id: A0A8C2U298
names: Subcellular Location Annotation
messages: Nucleus

93934:SUMF1
gene id: 93934:SUMF1
uniprot id: A0A8C2U7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase-modifying factor family.
messages: Endoplasmic reticulum lumen

93934:LOC107316590
gene id: 93934:LOC107316590
uniprot id: A0A8C2TYH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

93934:CALCRL
gene id: 93934:CALCRL
uniprot id: A0A8C2YCS3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for calcitonin-gene-related peptide (CGRP). Receptor specificity may be modulated by accessory proteins. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

93934:LOC107318663
gene id: 93934:LOC107318663
uniprot id: A0A8C2T7P4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R-hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin/ferredoxin).
messages: Belongs to the cytochrome P450 family.
messages: Mitochondrion inner membrane

93934:SF3A1
gene id: 93934:SF3A1
uniprot id: A0A8C2TSY7
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107314670
gene id: 93934:LOC107314670
uniprot id: A0A8C2TJP1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

93934:DRD2
gene id: 93934:DRD2
uniprot id: A0A8C2YC67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LOC107308548
gene id: 93934:LOC107308548
uniprot id: A0A8C2SVT9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

93934:LOC107321420
gene id: 93934:LOC107321420
uniprot id: A0A8C2TNP2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

93934:HAL
gene id: 93934:HAL
uniprot id: A0A8C2T0T5
names: Similarity
messages: Belongs to the PAL/histidase family.

93934:RPS17
gene id: 93934:RPS17
uniprot id: Q7ZUB2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

93934:RYR3
gene id: 93934:RYR3
uniprot id: A0A8C2U0P6
names: Subcellular Location Annotation
messages: Membrane
messages: Sarcoplasmic reticulum membrane

93934:ENPEP
gene id: 93934:ENPEP
uniprot id: A0A8C2T7J7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homodimer; disulfide-linked.

93934:TUBGCP4
gene id: 93934:TUBGCP4
uniprot id: A0A8C2SNY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome.
messages: centrosome

93934:SOX8
gene id: 93934:SOX8
uniprot id: A0A8C2T1W8
names: Subcellular Location Annotation
messages: Nucleus

93934:GDF5
gene id: 93934:GDF5
uniprot id: A0A8C2UCA3
names: Similarity
messages: Belongs to the TGF-beta family.

93934:PPP6C
gene id: 93934:PPP6C
uniprot id: A0A8C2TFR4
names: Similarity
messages: Belongs to the PPP phosphatase family.

93934:LOC107321524
gene id: 93934:LOC107321524
uniprot id: A0A8C2TAT3
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

93934:NUP107
gene id: 93934:NUP107
uniprot id: A0A8C2TX38
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

93934:SEMA3A
gene id: 93934:SEMA3A
uniprot id: A0A8C2SX49
uniprot id: A0A8C2Y711
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:BRAF
gene id: 93934:BRAF
uniprot id: P34908
names: Activity Regulation
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Cell membrane
messages: Cytoplasm
messages: Expressed preferentially in neural tissue.
messages: In quiescent cells, maintained in an inactive state via an intramolecular interaction between the protein kinase and N-terminal domains. Following mitogen-mediated cell activation, binds via its RGB domain to active HRAS (GTP-bound) which releases the inhibitory intramolecular interaction between the two domains. This allows the MAP2K1-mediated dimerization of KSR1 or KSR2, and BRAF which activates BRAF.
messages: Nucleus
messages: Phosphorylated.
messages: Protein kinase involved in the activation of the MAP signaling cascade. May play a role in transducing specific signals in neural cells.

93934:CA8
gene id: 93934:CA8
uniprot id: A0A8C2THG2
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.

93934:FAR1
gene id: 93934:FAR1
uniprot id: A0A8C2YFV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

93934:CHRNA6
gene id: 93934:CHRNA6
uniprot id: A0A8C2TJC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:ATL2
gene id: 93934:ATL2
uniprot id: A0A8C2Y6X8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family.

93934:CFAP45
gene id: 93934:CFAP45
uniprot id: A0A8C2TU00
names: Similarity
messages: Belongs to the CFAP45 family.

93934:MGST2
gene id: 93934:MGST2
uniprot id: A0A8C2SR29
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

93934:NIPAL2
gene id: 93934:NIPAL2
uniprot id: A0A8C2SPI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

93934:ATP6V0B
gene id: 93934:ATP6V0B
uniprot id: A0A8C2TDZ2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: clathrin-coated vesicle membrane

93934:LDHB
gene id: 93934:LDHB
uniprot id: A0A8C2STG5
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

93934:LOC107325174
gene id: 93934:LOC107325174
uniprot id: A0A8C2YEX9
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107308401
gene id: 93934:LOC107308401
uniprot id: A0A8C2ST91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: Secreted

93934:AGK
gene id: 93934:AGK
uniprot id: A0A8C2YH13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AGK family.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

93934:NGFR
gene id: 93934:NGFR
uniprot id: A0A8C2UCY5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:E2F3
gene id: 93934:E2F3
uniprot id: A0A8C2U690
uniprot id: A0A8C2U7P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

93934:SLC66A1L
gene id: 93934:SLC66A1L
uniprot id: A0A8C2U5V4
uniprot id: A0A8C2YFI1
names: Subcellular Location Annotation
messages: Membrane

93934:TCTEX1D2
gene id: 93934:TCTEX1D2
uniprot id: A0A8C2TNS5
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

93934:MFSD9
gene id: 93934:MFSD9
uniprot id: A0A8C2YCD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

93934:MAN1A2
gene id: 93934:MAN1A2
uniprot id: A0A8C2U264
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

93934:HGF
gene id: 93934:HGF
uniprot id: A0A8C2Y7A4
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S1 family. Plasminogen subfamily.
messages: Dimer of an alpha chain and a beta chain linked by a disulfide bond. Interacts with SRPX2; the interaction increases HGF mitogenic activity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization.

93934:IL6ST
gene id: 93934:IL6ST
uniprot id: A0A8C2SNB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

93934:AMFR
gene id: 93934:AMFR
uniprot id: A0A8C2SPV4
names: Subcellular Location Annotation
messages: Membrane

93934:CD320
gene id: 93934:CD320
uniprot id: A0A8C2T3C1
uniprot id: A0A8C2Y7X0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MIOS
gene id: 93934:MIOS
uniprot id: A0A8C2YB48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat mio family.
messages: Lysosome membrane

93934:EHF
gene id: 93934:EHF
uniprot id: A0A8C2TWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:AASDH
gene id: 93934:AASDH
uniprot id: A0A8C2TEC7
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:FOS
gene id: 93934:FOS
uniprot id: A0A8C2U7P7
names: Similarity
messages: Belongs to the bZIP family. Fos subfamily.

93934:ACMSD
gene id: 93934:ACMSD
uniprot id: A0A8C2UDH2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. ACMSD family.
messages: Converts alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). ACMS can be converted non-enzymatically to quinolate (QA), a key precursor of NAD, and a potent endogenous excitotoxin of neuronal cells which is implicated in the pathogenesis of various neurodegenerative disorders. In the presence of ACMSD, ACMS is converted to AMS, a benign catabolite. ACMSD ultimately controls the metabolic fate of tryptophan catabolism along the kynurenine pathway.
messages: Monomer.

93934:LOC107317369
gene id: 93934:LOC107317369
uniprot id: A0A8C2TBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Membrane
messages: Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinal to all-trans-retinol. May play a role in the regeneration of visual pigment at high light intensity.

93934:NIPAL4
gene id: 93934:NIPAL4
uniprot id: A0A8C2TJ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

93934:SLC7A13
gene id: 93934:SLC7A13
uniprot id: A0A8C2SN47
names: Subcellular Location Annotation
messages: Membrane

93934:EVX1
gene id: 93934:EVX1
uniprot id: A0A8C2TMQ0
names: Subcellular Location Annotation
messages: Nucleus

93934:NR0B1
gene id: 93934:NR0B1
uniprot id: A0A8C2U3N0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR0 subfamily.
messages: Cytoplasm
messages: Nucleus
messages: Orphan nuclear receptor. Component of a cascade required for the development of the hypothalamic-pituitary-adrenal-gonadal axis. Acts as a coregulatory protein that inhibits the transcriptional activity of other nuclear receptors through heterodimeric interactions. May also have a role in the development of the embryo and in the maintenance of embryonic stem cell pluripotency.

93934:SUCNR1
gene id: 93934:SUCNR1
uniprot id: A0A8C2U7A6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:SLC16A3
gene id: 93934:SLC16A3
uniprot id: A0A8C2UFI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

93934:LOC107308713
gene id: 93934:LOC107308713
uniprot id: A0A8C2T474
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:RC3H1
gene id: 93934:RC3H1
uniprot id: A0A8C2UIW0
names: Subcellular Location Annotation
messages: P-body

93934:TRAPPC2L
gene id: 93934:TRAPPC2L
uniprot id: A0A8C2YDF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

93934:LOC107324531
gene id: 93934:LOC107324531
uniprot id: A0A8C2TWZ4
names: Similarity
messages: Belongs to the calponin family.

93934:LOXL2
gene id: 93934:LOXL2
uniprot id: A0A8C2TWV7
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

93934:FAR2
gene id: 93934:FAR2
uniprot id: A0A8C2U0D6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acyl-CoA reductase family.
messages: Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
messages: Peroxisome membrane

93934:XPO5
gene id: 93934:XPO5
uniprot id: A0A8C2TJ08
names: Subcellular Location Annotation
messages: Cytoplasm

93934:TIPRL
gene id: 93934:TIPRL
uniprot id: A0A8C2U4N6
names: Similarity
messages: Belongs to the TIP41 family.

93934:BLMH
gene id: 93934:BLMH
uniprot id: A0A8C2TMQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm

93934:SPDYA
gene id: 93934:SPDYA
uniprot id: A0A8C2SPV3
names: Similarity
messages: Belongs to the Speedy/Ringo family.

93934:RAD50
gene id: 93934:RAD50
uniprot id: A0A8C2UGR1
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

93934:LOC107317829
gene id: 93934:LOC107317829
uniprot id: A0A8C2TUB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

93934:MAEL
gene id: 93934:MAEL
uniprot id: A0A8C2SUI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the maelstrom family.
messages: Nucleus
messages: Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

93934:LOC107320558
gene id: 93934:LOC107320558
uniprot id: A0A8C2YCL7
names: Function
names: Similarity
messages: Belongs to the parvalbumin family.
messages: In muscle, parvalbumin is thought to be involved in relaxation after contraction. It binds two calcium ions.

93934:RARB
gene id: 93934:RARB
uniprot id: A0A8C2TKW8
uniprot id: A0A8C2TP41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:FBXO31
gene id: 93934:FBXO31
uniprot id: A0A8C2TSQ4
uniprot id: A0A8C2TV36
uniprot id: A0A8C2TVP3
names: Similarity
names: Subunit
messages: Belongs to the FBXO31 family.
messages: Part of a SCF (SKP1-cullin-F-box) protein ligase complex.

93934:SLC18A3
gene id: 93934:SLC18A3
uniprot id: A0A8C2TP77
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107318671
gene id: 93934:LOC107318671
uniprot id: D0EX76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

93934:PDGFA
gene id: 93934:PDGFA
uniprot id: A0A8C2TSL1
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

93934:CITED2
gene id: 93934:CITED2
uniprot id: A0A8C2TBM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

93934:ANAPC13
gene id: 93934:ANAPC13
uniprot id: A0A8C2YG91
names: Function
names: Similarity
messages: Belongs to the APC13 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

93934:DTX2
gene id: 93934:DTX2
uniprot id: A0A8C2TES1
uniprot id: A0A8C2YA18
uniprot id: A0A8C2YA72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

93934:GRM5
gene id: 93934:GRM5
uniprot id: A0A8C2SUS0
uniprot id: A0A8C2SW18
uniprot id: A0A8C2Y6I7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: Membrane

93934:RRAD
gene id: 93934:RRAD
uniprot id: A0A8C2TVI8
names: Similarity
messages: Belongs to the small GTPase superfamily. RGK family.

93934:LCAT
gene id: 93934:LCAT
uniprot id: A0A8C2THH9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

93934:NR1H4
gene id: 93934:NR1H4
uniprot id: A0A8C2T644
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

93934:SLITRK3
gene id: 93934:SLITRK3
uniprot id: A0A8C2U4Y6
names: Similarity
messages: Belongs to the SLITRK family.

93934:CEBPB
gene id: 93934:CEBPB
uniprot id: A0A8C2T918
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

93934:KPNA2
gene id: 93934:KPNA2
uniprot id: A0A8C2UK10
names: Similarity
messages: Belongs to the importin alpha family.

93934:PRLHR
gene id: 93934:PRLHR
uniprot id: A0A8C2U9U1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:SLC26A1
gene id: 93934:SLC26A1
uniprot id: A0A8C2TM62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Mediates sulfate transport with high affinity. Mediates oxalate transport. Mediates bicarbonate transport. Does not accept succinate as cosubstrate.
messages: Membrane

93934:SPOP
gene id: 93934:SPOP
uniprot id: A0A8C2YGE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tdpoz family.
messages: Nucleus speckle

93934:CLDN3
gene id: 93934:CLDN3
uniprot id: A0A8C2SVD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the claudin family.
messages: Can form homo- and heteropolymers with other CLDN. Homopolymers interact with CLDN1 and CLDN2 homopolymers. Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:MYCN
gene id: 93934:MYCN
uniprot id: A0A8C2TIE8
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

93934:MB
gene id: 93934:MB
uniprot id: A0A8C2YFJ5
names: Function
names: Similarity
messages: Belongs to the globin family.
messages: Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

93934:IDE
gene id: 93934:IDE
uniprot id: A0A8C2U8D2
uniprot id: A0A8C2UDG1
names: Similarity
messages: Belongs to the peptidase M16 family.

93934:KERA
gene id: 93934:KERA
uniprot id: Q9DE66
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Cornea.
messages: Plays an important role in generating and maintaining a transparent matrix within the corneal stroma.
messages: extracellular matrix

93934:MMUT
gene id: 93934:MMUT
uniprot id: A0A8C2Y5M9
names: Function
names: Similarity
messages: Belongs to the methylmalonyl-CoA mutase family.
messages: Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.

93934:POT1
gene id: 93934:POT1
uniprot id: A0A8C2TP03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the telombin family.
messages: Nucleus
messages: telomere

93934:KEF80 p01
gene id: 93934:KEF80_p01
uniprot id: A0A1D9CQS2
uniprot id: P24981
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Mitochondrion membrane

93934:TMEM115
gene id: 93934:TMEM115
uniprot id: A0A8C2T2V7
names: Subcellular Location Annotation
messages: Membrane

93934:NDE1
gene id: 93934:NDE1
uniprot id: A0A8C2TIA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudE family.
messages: centrosome
messages: spindle

93934:UNC93B1
gene id: 93934:UNC93B1
uniprot id: A0A8C2TR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

93934:ARSK
gene id: 93934:ARSK
uniprot id: A0A8C2TLL0
names: PTM
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:LOC107316523
gene id: 93934:LOC107316523
uniprot id: A0A8C2TTP1
names: Similarity
messages: Belongs to the peptidase C14A family.

93934:LOC107305966
gene id: 93934:LOC107305966
uniprot id: A0A8C2YFM1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:AQP2
gene id: 93934:AQP2
uniprot id: A0A8C2STH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93934:GNA13
gene id: 93934:GNA13
uniprot id: A0A8C2UGW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-alpha family. G(12) subfamily.
messages: Membrane

93934:LOC107310340
gene id: 93934:LOC107310340
uniprot id: A0A1L5SAF8
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:DPEP1
gene id: 93934:DPEP1
uniprot id: A0A8C2TW01
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family.
messages: Cell membrane
messages: Homodimer; disulfide-linked.
messages: Independently of its dipeptidase activity, acts as an adhesion receptor for neutrophil recruitment from bloodstream into inflamed lungs and liver.
messages: Membrane

93934:LOC107310125
gene id: 93934:LOC107310125
uniprot id: A0A8C2TFT5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: desmosome

93934:LOC107325652
gene id: 93934:LOC107325652
uniprot id: A0A8C2TF70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:B4GALT4
gene id: 93934:B4GALT4
uniprot id: A0A8C2U2K2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

93934:CCDC58
gene id: 93934:CCDC58
uniprot id: A0A8C2U1C4
names: Similarity
messages: Belongs to the MIX23 family.

93934:GJA5
gene id: 93934:GJA5
uniprot id: A0A8C2SUL3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Alpha-type (group II) subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:RNASET2
gene id: 93934:RNASET2
uniprot id: A0A8C2SXA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Lysosome lumen

93934:MASP1
gene id: 93934:MASP1
uniprot id: A0A8C2TPG9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ROCK2
gene id: 93934:ROCK2
uniprot id: A0A8C2TFP6
uniprot id: A0A8C2THQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
messages: Cell membrane
messages: Membrane
messages: centrosome

93934:MATK
gene id: 93934:MATK
uniprot id: A0A8C2T0J9
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:SMPDL3A
gene id: 93934:SMPDL3A
uniprot id: A0A8C2Y9T1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

93934:SGSM1
gene id: 93934:SGSM1
uniprot id: A0A8C2TCS3
names: Similarity
messages: Belongs to the RUTBC family.

93934:RPS3A
gene id: 93934:RPS3A
uniprot id: A0A8C2T443
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S).
messages: Cytoplasm

93934:LYVE1
gene id: 93934:LYVE1
uniprot id: A0A8C2SSQ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107323516
gene id: 93934:LOC107323516
uniprot id: A0A8C2TH52
uniprot id: A0A8C2TK77
names: Similarity
messages: Belongs to the DDI1 family.

93934:LOC107320564
gene id: 93934:LOC107320564
uniprot id: A0A8C2YCY8
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:FAM151B
gene id: 93934:FAM151B
uniprot id: A0A8C2SQS2
names: Similarity
messages: Belongs to the FAM151 family.

93934:TXNRD3
gene id: 93934:TXNRD3
uniprot id: A0A8C2TW47
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

93934:AVL9
gene id: 93934:AVL9
uniprot id: A0A8C2Y8C7
names: Subcellular Location Annotation
messages: Endosome
messages: Recycling endosome

93934:RFNG
gene id: 93934:RFNG
uniprot id: A0A8C2UFF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:STX7
gene id: 93934:STX7
uniprot id: A0A8C2T8X7
names: Similarity
messages: Belongs to the syntaxin family.

93934:NUBPL
gene id: 93934:NUBPL
uniprot id: A0A8C2YF47
names: Similarity
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.

93934:BORCS8
gene id: 93934:BORCS8
uniprot id: A0A8C2TJ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BORCS8 family.
messages: Lysosome membrane
messages: Membrane

93934:LOC107320189
gene id: 93934:LOC107320189
uniprot id: A0A8C2U2N6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

93934:KCNK9
gene id: 93934:KCNK9
uniprot id: A0A8C2YAD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane
messages: pH-dependent, voltage-insensitive, background potassium channel protein.

93934:SLC1A3
gene id: 93934:SLC1A3
uniprot id: A0A8C2T3W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

93934:WDR4
gene id: 93934:WDR4
uniprot id: A0A8C2TAJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit METTL1.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

93934:CRYGS
gene id: 93934:CRYGS
uniprot id: A0A8C2U730
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

93934:LOC107318190
gene id: 93934:LOC107318190
uniprot id: A0A8C2TMP1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:MYMK
gene id: 93934:MYMK
uniprot id: A0A8C2T5C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM8 family.
messages: Cell membrane
messages: Membrane

93934:BABAM2
gene id: 93934:BABAM2
uniprot id: A0A8C2YAA2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BABAM2 family.
messages: Component of the ARISC complex. Component of the BRCA1-A complex. Component of the BRISC complex. Binds polyubiquitin.
messages: Contains 2 ubiquitin-conjugating enzyme family-like (UEV-like) regions. These regions lack the critical Cys residues required for ubiquitination but retain the ability to bind ubiquitin.
messages: Cytoplasm
messages: May play a role in homeostasis or cellular differentiation in cells of neural, epithelial and germline origins. May also act as a death receptor-associated anti-apoptotic protein, which inhibits the mitochondrial apoptotic pathway.
messages: Nucleus

93934:PRDM13
gene id: 93934:PRDM13
uniprot id: A0A8C2TD33
names: Subcellular Location Annotation
messages: Nucleus

93934:NR4A3
gene id: 93934:NR4A3
uniprot id: A0A8C2T314
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:LOC107324446
gene id: 93934:LOC107324446
uniprot id: A0A8C2YER1
names: Subcellular Location Annotation
messages: Membrane

93934:SLC25A30
gene id: 93934:SLC25A30
uniprot id: A0A8C2UE83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:LOC107319866
gene id: 93934:LOC107319866
uniprot id: A0A8C2TTV2
names: Similarity
messages: Belongs to the filamin family.

93934:URM1
gene id: 93934:URM1
uniprot id: A0A8C2U9T7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of MOCS3, then thiocarboxylated (-COSH) via the rhodanese domain of MOCS3.
messages: Cytoplasm

93934:WIPI2
gene id: 93934:WIPI2
uniprot id: A0A8C2SPP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat PROPPIN family.
messages: Preautophagosomal structure membrane

93934:LOC107306300
gene id: 93934:LOC107306300
uniprot id: A0A8C2Y9W5
names: Similarity
messages: Belongs to the TPPP family.

93934:LOC107321044
gene id: 93934:LOC107321044
uniprot id: A0A8C2U7J7
uniprot id: A0A8C2U9L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

93934:INTS14
gene id: 93934:INTS14
uniprot id: A0A8C2UEW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INTS14 family.
messages: Nucleus
messages: Probable component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing.

93934:LSM1
gene id: 93934:LSM1
uniprot id: A0A8C2TTH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Cytoplasm
messages: LSm subunits form a heteromer with a donut shape.
messages: P-body
messages: Probably involved with other LSm subunits in the general process of degradation of mRNAs.

93934:NTSR1
gene id: 93934:NTSR1
uniprot id: A0A8C2ST05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:MED18
gene id: 93934:MED18
uniprot id: A0A8C2SRL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:KATNAL1
gene id: 93934:KATNAL1
uniprot id: A0A8C2UAY8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 1 sub-subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: Interacts with KATNB1 and KATNBL1.
messages: Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

93934:USP3
gene id: 93934:USP3
uniprot id: A0A8C2T8U8
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:GOT2
gene id: 93934:GOT2
uniprot id: A0A8C2T598
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

93934:MINPP1
gene id: 93934:MINPP1
uniprot id: A0A8C2TMA7
names: Similarity
messages: Belongs to the histidine acid phosphatase family. MINPP1 subfamily.

93934:PCSK1
gene id: 93934:PCSK1
uniprot id: A0A8C2TKW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S8 family.
messages: Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
messages: Vesicle
messages: secretory vesicle

93934:KEF80 p04
gene id: 93934:KEF80_p04
uniprot id: Q8SEW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
messages: Membrane
messages: Mitochondrion membrane

93934:MYC
gene id: 93934:MYC
uniprot id: A0A8C2T578
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus
messages: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.

93934:EDN3
gene id: 93934:EDN3
uniprot id: A0A8C2T718
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

93934:NTF3
gene id: 93934:NTF3
uniprot id: A0A8C2TX07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Secreted
messages: Seems to promote the survival of visceral and proprioceptive sensory neurons.

93934:CFDP1
gene id: 93934:CFDP1
uniprot id: A0A8C2SY06
names: Function
names: Subcellular Location Annotation
messages: May play a role during embryogenesis.
messages: kinetochore

93934:JPT2
gene id: 93934:JPT2
uniprot id: A0A8C2U2H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the JUPITER family.
messages: Cytoplasm
messages: Nucleus

93934:ERGIC2
gene id: 93934:ERGIC2
uniprot id: A0A8C2T6E9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

93934:TBR1
gene id: 93934:TBR1
uniprot id: A0A8C2TUG5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:HS3ST2
gene id: 93934:HS3ST2
uniprot id: A0A8C2TGY7
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:CHMP1B
gene id: 93934:CHMP1B
uniprot id: A0A8C2ST45
names: Similarity
messages: Belongs to the SNF7 family.

93934:RNASEH2B
gene id: 93934:RNASEH2B
uniprot id: A0A8C2UCI1
uniprot id: A0A8C2UEA1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H2 subunit B family.
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus
messages: The RNase H2 complex is a heterotrimer composed of the catalytic subunit RNASEH2A and the non-catalytic subunits RNASEH2B and RNASEH2C.

93934:LOC107308550
gene id: 93934:LOC107308550
uniprot id: A0A8C2SYA0
names: Subcellular Location Annotation
messages: Cytoplasm

93934:LEPR
gene id: 93934:LEPR
uniprot id: A0A8C2TUE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

93934:CSE1L
gene id: 93934:CSE1L
uniprot id: A0A8C2ST30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPO2/CSE1 family.
messages: Cytoplasm

93934:LOC107310235
gene id: 93934:LOC107310235
uniprot id: A0A8C2TKM7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

93934:LOC107323806
gene id: 93934:LOC107323806
uniprot id: A0A8C2SX79
names: Similarity
messages: Belongs to the TGF-beta family.

93934:BCO1
gene id: 93934:BCO1
uniprot id: A0A8C2TWJ7
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

93934:UXS1
gene id: 93934:UXS1
uniprot id: A0A8C2TME4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.
messages: Golgi stack membrane
messages: Membrane

93934:MTMR12
gene id: 93934:MTMR12
uniprot id: A0A8C2T1P4
uniprot id: A0A8C2T285
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Sarcoplasmic reticulum
messages: sarcomere

93934:ATP1B3
gene id: 93934:ATP1B3
uniprot id: A0A8C2Y9W4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

93934:CHSY1
gene id: 93934:CHSY1
uniprot id: A0A8C2UC74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

93934:NAB1
gene id: 93934:NAB1
uniprot id: A0A8C2TRL9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAB family.
messages: Homomultimers may associate with EGR1 bound to DNA.
messages: Nucleus

93934:SULT1C4
gene id: 93934:SULT1C4
uniprot id: A0A8C2TQ05
uniprot id: A0A8C2YCE0
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:ASXL3
gene id: 93934:ASXL3
uniprot id: A0A8C2TC38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

93934:CCND3
gene id: 93934:CCND3
uniprot id: A0A8C2YG33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

93934:MAP2K3
gene id: 93934:MAP2K3
uniprot id: A0A8C2SPH9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:ERN2
gene id: 93934:ERN2
uniprot id: A0A8C2TGX9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ATG5
gene id: 93934:ATG5
uniprot id: A0A8C2TG16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in autophagic vesicle formation. Conjugation with ATG12, through a ubiquitin-like conjugating system involving ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. Involved in mitochondrial quality control after oxidative damage, and in subsequent cellular longevity. Plays a critical role in multiple aspects of lymphocyte development and is essential for both B and T lymphocyte survival and proliferation. Required for optimal processing and presentation of antigens for MHC II. Involved in the maintenance of axon morphology and membrane structures, as well as in normal adipocyte differentiation. Promotes primary ciliogenesis through removal of OFD1 from centriolar satellites and degradation of IFT20 via the autophagic pathway.
messages: May play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity. Plays a crucial role in IFN-gamma-induced autophagic cell death by interacting with FADD.
messages: Preautophagosomal structure membrane

93934:SMOC1
gene id: 93934:SMOC1
uniprot id: A0A8C2TWC1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:EZH1
gene id: 93934:EZH1
uniprot id: A0A8C2T2X1
uniprot id: A0A8C2Y789
names: Subcellular Location Annotation
messages: Nucleus

93934:PIGV
gene id: 93934:PIGV
uniprot id: A0A8C2TUV0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

93934:TIMM10
gene id: 93934:TIMM10
uniprot id: A0A8C2YF55
names: Function
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. May also be required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.

93934:SMPDL3B
gene id: 93934:SMPDL3B
uniprot id: A0A8C2TY55
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) per subunit.
messages: Secreted

93934:ARL8B
gene id: 93934:ARL8B
uniprot id: A0A8C2UE28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

93934:TLCD5
gene id: 93934:TLCD5
uniprot id: A0A8C2TAG1
names: Subcellular Location Annotation
messages: Membrane

93934:SYBU
gene id: 93934:SYBU
uniprot id: A0A8C2SXR1
names: Subcellular Location Annotation
messages: Membrane

93934:PPP2R2D
gene id: 93934:PPP2R2D
uniprot id: A0A8C2SPK2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

93934:SH3YL1
gene id: 93934:SH3YL1
uniprot id: A0A8C2Y909
names: Similarity
messages: Belongs to the SH3YL1 family.

93934:CXCL12
gene id: 93934:CXCL12
uniprot id: A0A8C2YG30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Secreted

93934:PFN4
gene id: 93934:PFN4
uniprot id: A0A8C2THL4
names: Similarity
messages: Belongs to the profilin family.

93934:ARSB
gene id: 93934:ARSB
uniprot id: A0A8C2T605
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:MYOD1
gene id: 93934:MYOD1
uniprot id: P21572
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
messages: Efficient DNA binding requires dimerization with another bHLH protein. Seems to form active heterodimers with ITF-2.
messages: Nucleus

93934:SPIN1
gene id: 93934:SPIN1
uniprot id: A0A8C2TB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPIN/STSY family.
messages: Nucleus

93934:SEPTIN11
gene id: 93934:SEPTIN11
uniprot id: A0A8C2SP11
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

93934:CPNE7
gene id: 93934:CPNE7
uniprot id: A0A8C2TTL8
names: Similarity
messages: Belongs to the copine family.

93934:IL18R1
gene id: 93934:IL18R1
uniprot id: A0A8C2TRH1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

93934:SHH
gene id: 93934:SHH
uniprot id: A0A8C2SU13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

93934:INO80D
gene id: 93934:INO80D
uniprot id: A0A8C2TZ75
names: Subcellular Location Annotation
messages: Nucleus

93934:CDK6
gene id: 93934:CDK6
uniprot id: A0A8C2TGY6
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:HBEGF
gene id: 93934:HBEGF
uniprot id: A0A8C2TM59
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SLC7A11
gene id: 93934:SLC7A11
uniprot id: A0A8C2Y513
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

93934:DMGDH
gene id: 93934:DMGDH
uniprot id: A0A8C2T8E5
names: Similarity
messages: Belongs to the GcvT family.

93934:POGLUT3
gene id: 93934:POGLUT3
uniprot id: A0A8C2SPI1
names: Similarity
messages: Belongs to the KDELC family.

93934:TAF5
gene id: 93934:TAF5
uniprot id: A0A8C2UBQ4
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

93934:NOX3
gene id: 93934:NOX3
uniprot id: A0A8C2T8G1
names: Subcellular Location Annotation
messages: Membrane

93934:RPL18A
gene id: 93934:RPL18A
uniprot id: A0A8C2TYQ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

93934:CKAP2
gene id: 93934:CKAP2
uniprot id: A0A8C2YGQ0
names: Similarity
messages: Belongs to the CKAP2 family.

93934:SLC12A9
gene id: 93934:SLC12A9
uniprot id: A0A8C2TSI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

93934:NKX2-1
gene id: 93934:NKX2-1
uniprot id: A0A8C2U6L1
names: Subcellular Location Annotation
messages: Nucleus

93934:AKIRIN2
gene id: 93934:AKIRIN2
uniprot id: A0A8C2SV01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the akirin family.
messages: Nucleus

93934:RPL27A
gene id: 93934:RPL27A
uniprot id: A0A8C2SYB5
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

93934:GTF2H1
gene id: 93934:GTF2H1
uniprot id: A0A8C2YAT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

93934:ALDH1A3
gene id: 93934:ALDH1A3
uniprot id: A0A8C2UCP7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93934:TXNL4A
gene id: 93934:TXNL4A
uniprot id: A0A8C2U6Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

93934:STT3A
gene id: 93934:STT3A
uniprot id: A0A8C2T2B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

93934:LYRM7
gene id: 93934:LYRM7
uniprot id: A0A8C2TEU7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII) complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner membrane.
messages: Belongs to the complex I LYR family.
messages: Interacts with UQCRFS1.
messages: Mitochondrion matrix

93934:SDAD1
gene id: 93934:SDAD1
uniprot id: A0A8C2SMD0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

93934:RIN2
gene id: 93934:RIN2
uniprot id: A0A8C2TUQ0
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

93934:ATP6AP1L
gene id: 93934:ATP6AP1L
uniprot id: A0A8C2SNN3
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

93934:DDX51
gene id: 93934:DDX51
uniprot id: A0A8C2T7Y0
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:ADAMTS8
gene id: 93934:ADAMTS8
uniprot id: A0A8C2Y800
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:RPL19
gene id: 93934:RPL19
uniprot id: S4VAQ3
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL19 family.
messages: Component of the large ribosomal subunit.

93934:PRPSAP2
gene id: 93934:PRPSAP2
uniprot id: A0A8C2SWN9
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

93934:LOC107310840
gene id: 93934:LOC107310840
uniprot id: A0A8C2SN06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.

93934:STIM2
gene id: 93934:STIM2
uniprot id: A0A8C2U678
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:RPL5
gene id: 93934:RPL5
uniprot id: A0A8C2T8J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

93934:STAT1
gene id: 93934:STAT1
uniprot id: A0A8C2TE68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

93934:PDGFC
gene id: 93934:PDGFC
uniprot id: A0A8C2Y4T0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:QTRT2
gene id: 93934:QTRT2
uniprot id: A0A8C2YF36
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Heterodimer of a catalytic subunit QTRT1 and an accessory subunit QTRT2.
messages: Mitochondrion outer membrane
messages: Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).

93934:FAM110C
gene id: 93934:FAM110C
uniprot id: A0A8C2TAG4
names: Similarity
messages: Belongs to the FAM110 family.

93934:LOC107322710
gene id: 93934:LOC107322710
uniprot id: A0A8C2SWM7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:SDC1
gene id: 93934:SDC1
uniprot id: A0A8C2TLA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane
messages: extracellular exosome

93934:INPP5B
gene id: 93934:INPP5B
uniprot id: A0A8C2U2R1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type II family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: phagosome membrane

93934:FAM120A
gene id: 93934:FAM120A
uniprot id: A0A8C2YC18
names: Similarity
messages: Belongs to the constitutive coactivator of PPAR-gamma family.

93934:GALNT6
gene id: 93934:GALNT6
uniprot id: A0A8C2SW14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:PRKCA
gene id: 93934:PRKCA
uniprot id: A0A8C2UGG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Mitochondrion membrane
messages: Nucleus

93934:TADA2A
gene id: 93934:TADA2A
uniprot id: A0A8C2U6X1
names: Subcellular Location Annotation
messages: Nucleus

93934:RRH
gene id: 93934:RRH
uniprot id: A0A8C2Y8B8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:AQR
gene id: 93934:AQR
uniprot id: A0A8C2U306
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CWF11 family.
messages: Nucleus

93934:CCSER2
gene id: 93934:CCSER2
uniprot id: A0A8C2TMX4
uniprot id: A0A8C2TPL1
uniprot id: A0A8C2YBT1
names: Similarity
messages: Belongs to the CCSER family.

93934:VPS36
gene id: 93934:VPS36
uniprot id: A0A8C2UCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

93934:NRP1
gene id: 93934:NRP1
uniprot id: A0A8C2SSF1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:NOB1
gene id: 93934:NOB1
uniprot id: A0A8C2TU70
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: May play a role in mRNA degradation.
messages: Nucleus

93934:LOC107312127
gene id: 93934:LOC107312127
uniprot id: A0A8C2T5M0
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

93934:LOC107317137
gene id: 93934:LOC107317137
uniprot id: A0A8C2SW74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with VGF-derived peptide TLQP-21.
messages: Membrane
messages: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

93934:LOC107318775
gene id: 93934:LOC107318775
uniprot id: A0A8C2UD14
uniprot id: A0A8C2UFZ8
names: Similarity
messages: Belongs to the intermediate filament family.

93934:LOC107314288
gene id: 93934:LOC107314288
uniprot id: A0A8C2TPH7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

93934:NOP16
gene id: 93934:NOP16
uniprot id: A0A8C2TJL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: nucleolus

93934:GOSR1
gene id: 93934:GOSR1
uniprot id: A0A8C2TRJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an important physiological role in VLDL-transport vesicle-Golgi fusion and thus in VLDL delivery to the hepatic cis-Golgi.
messages: Membrane

93934:GRID2
gene id: 93934:GRID2
uniprot id: A0A8C2T9N8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:CAPN3
gene id: 93934:CAPN3
uniprot id: A0A8C2TRW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C2 family.
messages: Calcium-regulated non-lysosomal thiol-protease.
messages: Cytoplasm
messages: Homodimer.
messages: nucleolus

93934:CA9
gene id: 93934:CA9
uniprot id: A0A8C2T1M4
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93934:SLC1A1
gene id: 93934:SLC1A1
uniprot id: A0A8C2SS49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

93934:FASN
gene id: 93934:FASN
uniprot id: A0A8C2UG39
names: Function
messages: Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

93934:RPS6KA2
gene id: 93934:RPS6KA2
uniprot id: A0A8C2SXQ1
uniprot id: A0A8C2Y6G0
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

93934:KCNMB1
gene id: 93934:KCNMB1
uniprot id: A0A8C2TGJ4
names: Subcellular Location Annotation
messages: Membrane

93934:SLF2
gene id: 93934:SLF2
uniprot id: A0A8C2YGT9
names: Similarity
messages: Belongs to the FAM178 family.

93934:CAPN2
gene id: 93934:CAPN2
uniprot id: A0A8C2Y8C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C2 family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

93934:MTAP
gene id: 93934:MTAP
uniprot id: A0A8C2Y7U8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

93934:TRIAP1
gene id: 93934:TRIAP1
uniprot id: A0A8C2TN16
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

93934:LOC107310827
gene id: 93934:LOC107310827
uniprot id: A0A8C2U1B3
names: Similarity
messages: Belongs to the CRISP family.

93934:MSH2
gene id: 93934:MSH2
uniprot id: A0A8C2SPW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

93934:C21H1orf174
gene id: 93934:C21H1orf174
uniprot id: A0A8C2TAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0688 family.
messages: Nucleus

93934:CCDC39
gene id: 93934:CCDC39
uniprot id: A0A8C2TRQ8
names: Similarity
messages: Belongs to the CCDC39 family.

93934:ENO4
gene id: 93934:ENO4
uniprot id: A0A8C2UCH1
names: Similarity
messages: Belongs to the enolase family.

93934:ITGA6
gene id: 93934:ITGA6
uniprot id: A0A8C2U4E9
uniprot id: A0A8C2U7P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

93934:LOC107314549
gene id: 93934:LOC107314549
uniprot id: A0A8C2U825
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:TMEM168
gene id: 93934:TMEM168
uniprot id: A0A8C2TRZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM168 family.
messages: Membrane

93934:VPS35L
gene id: 93934:VPS35L
uniprot id: A0A8C2U9E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS35L family.
messages: Endosome

93934:UNC93A
gene id: 93934:UNC93A
uniprot id: A0A8C2SVM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-93 family.
messages: Membrane

93934:LOC107308521
gene id: 93934:LOC107308521
uniprot id: A0A8C2T177
names: Similarity
messages: Belongs to the Arg-specific ADP-ribosyltransferase family.

93934:PCYOX1L
gene id: 93934:PCYOX1L
uniprot id: A0A8C2Y9D9
names: Similarity
messages: Belongs to the prenylcysteine oxidase family.

93934:SLC6A11
gene id: 93934:SLC6A11
uniprot id: A0A8C2TN87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

93934:PGM5
gene id: 93934:PGM5
uniprot id: A0A8C2SPT8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

93934:MFAP3L
gene id: 93934:MFAP3L
uniprot id: A0A8C2SPA6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:ACTR6
gene id: 93934:ACTR6
uniprot id: A0A8C2T4Y8
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.

93934:LOC107312608
gene id: 93934:LOC107312608
uniprot id: A0A8C2Y5U4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:MPP5
gene id: 93934:MPP5
uniprot id: A0A8C2U5V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: tight junction

93934:RRP1B
gene id: 93934:RRP1B
uniprot id: A0A8C2T8D2
names: Similarity
messages: Belongs to the RRP1 family.

93934:SEC11C
gene id: 93934:SEC11C
uniprot id: A0A8C2SXH0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:AKR1D1
gene id: 93934:AKR1D1
uniprot id: A0A8C2UCR2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

93934:TMEM182
gene id: 93934:TMEM182
uniprot id: A0A8C2TPY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM182 family.
messages: Cell membrane
messages: Membrane

93934:RBM15B
gene id: 93934:RBM15B
uniprot id: A0A8C2TE96
names: Similarity
messages: Belongs to the RRM Spen family.

93934:NINJ1
gene id: 93934:NINJ1
uniprot id: A0A8C2TPS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

93934:LOC107320290
gene id: 93934:LOC107320290
uniprot id: A0A8C2TJC4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:NT5C3A
gene id: 93934:NT5C3A
uniprot id: A0A8C2T5E4
uniprot id: A0A8C2Y8C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrimidine 5'-nucleotidase family.
messages: Cytoplasm

93934:AKR1A1
gene id: 93934:AKR1A1
uniprot id: A0A8C2THJ2
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the aldo/keto reductase family.
messages: Cell membrane
messages: Membrane
messages: cytosol

93934:ATF1
gene id: 93934:ATF1
uniprot id: A0A8C2U8H0
names: Subcellular Location Annotation
messages: Nucleus

93934:PRKG2
gene id: 93934:PRKG2
uniprot id: A0A8C2TCH9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cGMP subfamily.

93934:DRD4
gene id: 93934:DRD4
uniprot id: A0A8C2YCK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LOC107315868
gene id: 93934:LOC107315868
uniprot id: A0A8C2U6E1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

93934:PRKRIP1
gene id: 93934:PRKRIP1
uniprot id: A0A8C2YA16
names: Similarity
messages: Belongs to the PRKRIP1 family.

93934:PLPPR1
gene id: 93934:PLPPR1
uniprot id: A0A8C2SQ63
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Cell membrane
messages: May play a role in neurite outgrowth and neurogenesis.
messages: Membrane
messages: neuron projection

93934:DLX1
gene id: 93934:DLX1
uniprot id: A0A8C2U5S5
names: Subcellular Location Annotation
messages: Nucleus

93934:THRAP3
gene id: 93934:THRAP3
uniprot id: A0A8C2U2D5
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

93934:C1H2orf49
gene id: 93934:C1H2orf49
uniprot id: A0A8C2TN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ashwin family.
messages: Nucleus

93934:LOC107322624
gene id: 93934:LOC107322624
uniprot id: A0A8C2SVH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

93934:PIH1D2
gene id: 93934:PIH1D2
uniprot id: A0A8C2TQ35
names: Similarity
messages: Belongs to the PIH1 family.

93934:LOC107316254
gene id: 93934:LOC107316254
uniprot id: A0A8C2UDU0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:KCNS1
gene id: 93934:KCNS1
uniprot id: A0A8C2UD18
names: Subcellular Location Annotation
messages: Membrane

93934:NDUFA6
gene id: 93934:NDUFA6
uniprot id: A0A8C2T9D3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

93934:EMC6
gene id: 93934:EMC6
uniprot id: A0A8C2TY85
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC6 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:SLC25A48
gene id: 93934:SLC25A48
uniprot id: A0A8C2T196
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:RXFP1
gene id: 93934:RXFP1
uniprot id: A0A8C2SMN2
names: Caution
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TRMT2A
gene id: 93934:TRMT2A
uniprot id: A0A8C2UAD3
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:UNC45A
gene id: 93934:UNC45A
uniprot id: A0A8C2UJE6
names: Subcellular Location Annotation
messages: perinuclear region

93934:KEF80 p13
gene id: 93934:KEF80_p13
uniprot id: A0A1D9CQQ9
uniprot id: P24968
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 1 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
messages: Membrane
messages: Mitochondrion inner membrane

93934:PLA2G15
gene id: 93934:PLA2G15
uniprot id: A0A8C2TJS8
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

93934:TM9SF4
gene id: 93934:TM9SF4
uniprot id: A0A8C2SY90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

93934:STS
gene id: 93934:STS
uniprot id: A0A8C2YFK9
uniprot id: A0A8C2YFL9
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:ICMT
gene id: 93934:ICMT
uniprot id: A0A8C2T750
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Catalyzes the post-translational methylation of isoprenylated C-terminal cysteine residues.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:RBP1
gene id: 93934:RBP1
uniprot id: A0A8C2SZA0
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:SPOCK1
gene id: 93934:SPOCK1
uniprot id: A0A8C2SZ01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107315066
gene id: 93934:LOC107315066
uniprot id: A0A8C2SXR3
names: Caution
names: Function
names: Subunit
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
messages: Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

93934:CLCC1
gene id: 93934:CLCC1
uniprot id: A0A8C2UJ87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel MCLC family.
messages: Membrane
messages: Nucleus membrane

93934:TMEM50B
gene id: 93934:TMEM50B
uniprot id: A0A8C2SZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

93934:RTCA
gene id: 93934:RTCA
uniprot id: A0A8C2UH82
names: Function
names: Similarity
messages: Belongs to the RNA 3'-terminal cyclase family. Type 1 subfamily.
messages: Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.

93934:ALX1
gene id: 93934:ALX1
uniprot id: A0A8C2SYJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

93934:EVA1C
gene id: 93934:EVA1C
uniprot id: A0A8C2SZY0
names: Similarity
messages: Belongs to the EVA1 family.

93934:LOC107309689
gene id: 93934:LOC107309689
uniprot id: A0A8C2U3J3
uniprot id: A0A8C2U3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TRSPAP family.
messages: Cytoplasm
messages: Nucleus

93934:LHFPL3
gene id: 93934:LHFPL3
uniprot id: A0A8C2T4N9
uniprot id: A0A8C2T6F3
names: Subcellular Location Annotation
messages: Membrane

93934:MESD
gene id: 93934:MESD
uniprot id: A0A8C2UF03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MESD family.
messages: Endoplasmic reticulum

93934:GRPR
gene id: 93934:GRPR
uniprot id: A0A8C2U766
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:DKK3
gene id: 93934:DKK3
uniprot id: A0A8C2Y5C6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dickkopf family.
messages: Secreted

93934:TASOR
gene id: 93934:TASOR
uniprot id: A0A8C2TMP8
uniprot id: A0A8C2TN63
names: Similarity
messages: Belongs to the TASOR family.

93934:NAA25
gene id: 93934:NAA25
uniprot id: A0A8C2T7I2
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

93934:GTPBP10
gene id: 93934:GTPBP10
uniprot id: A0A8C2T1Z8
names: Similarity
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.

93934:NOL10
gene id: 93934:NOL10
uniprot id: A0A8C2TIT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

93934:AGRN
gene id: 93934:AGRN
uniprot id: A0A8C2TIT9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SLC25A22
gene id: 93934:SLC25A22
uniprot id: A0A8C2YFS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:UBLCP1
gene id: 93934:UBLCP1
uniprot id: A0A8C2TGH5
names: Function
names: Subcellular Location Annotation
messages: Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.
messages: Nucleus

93934:CTNNB1
gene id: 93934:CTNNB1
uniprot id: A0A8C2SZ06
names: Similarity
messages: Belongs to the beta-catenin family.

93934:EFNA5
gene id: 93934:EFNA5
uniprot id: A0A8C2Y9Y2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:IRF5
gene id: 93934:IRF5
uniprot id: A0A8C2Y4R8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:GOLPH3L
gene id: 93934:GOLPH3L
uniprot id: A0A8C2TVS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

93934:NME6
gene id: 93934:NME6
uniprot id: A0A8C2SMR4
names: Similarity
messages: Belongs to the NDK family.

93934:EOMES
gene id: 93934:EOMES
uniprot id: A0A8C2TPZ0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:NFRKB
gene id: 93934:NFRKB
uniprot id: A0A8C2T3E9
names: Subcellular Location Annotation
messages: Nucleus

93934:NKX2-3
gene id: 93934:NKX2-3
uniprot id: A0A8C2YGG7
names: Subcellular Location Annotation
messages: Nucleus

93934:EDNRB
gene id: 93934:EDNRB
uniprot id: A0A8C2UDC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SLC39A13
gene id: 93934:SLC39A13
uniprot id: A0A8C2TEZ4
names: Subcellular Location Annotation
messages: Membrane

93934:TRAPPC3
gene id: 93934:TRAPPC3
uniprot id: A0A8C2TZR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

93934:CLDN2
gene id: 93934:CLDN2
uniprot id: A0A8C2U4L1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:LOC107308741
gene id: 93934:LOC107308741
uniprot id: A0A1Q2TSD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

93934:LOC107306667
gene id: 93934:LOC107306667
uniprot id: A0A8C2T1V5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

93934:KIF13B
gene id: 93934:KIF13B
uniprot id: A0A8C2TLN6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:DNAJB14
gene id: 93934:DNAJB14
uniprot id: A0A8C2T356
names: Subcellular Location Annotation
messages: Membrane

93934:ARHGEF6
gene id: 93934:ARHGEF6
uniprot id: A0A8C2U2S0
names: Subcellular Location Annotation
messages: lamellipodium

93934:NCBP3
gene id: 93934:NCBP3
uniprot id: A0A8C2YAP7
names: Similarity
messages: Belongs to the NCBP3 family.

93934:TFAP2A
gene id: 93934:TFAP2A
uniprot id: A0A8C2U563
uniprot id: A0A8C2YEV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AP-2 family.
messages: Nucleus

93934:SDF4
gene id: 93934:SDF4
uniprot id: A0A8C2YAY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREC family.
messages: Golgi apparatus lumen

93934:LOC107308462
gene id: 93934:LOC107308462
uniprot id: A0A8C2SXL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

93934:ITM2C
gene id: 93934:ITM2C
uniprot id: A0A8C2Y7K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

93934:SIX6
gene id: 93934:SIX6
uniprot id: A0A8C2SZS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

93934:ERCC4
gene id: 93934:ERCC4
uniprot id: A0A8C2TSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPF family.
messages: Nucleus

93934:KCNJ5
gene id: 93934:KCNJ5
uniprot id: A0A8C2Y7W2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ5 subfamily.
messages: Membrane

93934:FOXA2
gene id: 93934:FOXA2
uniprot id: A0A8C2TYZ6
names: Subcellular Location Annotation
messages: Nucleus

93934:SNU13
gene id: 93934:SNU13
uniprot id: A0A8C2TBS1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

93934:TFB1M
gene id: 93934:TFB1M
uniprot id: A0A8C2T7U6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.

93934:NR2E1
gene id: 93934:NR2E1
uniprot id: A0A8C2TFY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:MOCS2
gene id: 93934:MOCS2
uniprot id: A0A8C2YAT9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MoaE family. MOCS2B subfamily.
messages: Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group.
messages: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits.
messages: This protein is produced by a bicistronic gene which also produces the large subunit (MOCS2A).
messages: cytosol

93934:IFNAR2
gene id: 93934:IFNAR2
uniprot id: A0A8C2Y7C1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

93934:SLC13A1
gene id: 93934:SLC13A1
uniprot id: A0A8C2YBJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

93934:GLRB
gene id: 93934:GLRB
uniprot id: A0A8C2Y514
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Membrane

93934:MTRF1L
gene id: 93934:MTRF1L
uniprot id: A0A8C2T875
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

93934:SLCO4C1
gene id: 93934:SLCO4C1
uniprot id: A0A8C2TBG2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:HSPB2
gene id: 93934:HSPB2
uniprot id: A0A8C2YCU0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93934:GALR1
gene id: 93934:GALR1
uniprot id: A0A8C2T6W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:UBQLN1
gene id: 93934:UBQLN1
uniprot id: A0A8C2TAC4
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus
messages: autophagosome

93934:MSH4
gene id: 93934:MSH4
uniprot id: A0A8C2TST1
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.

93934:BET1
gene id: 93934:BET1
uniprot id: A0A8C2TDW4
names: Subcellular Location Annotation
messages: Membrane

93934:PDP1
gene id: 93934:PDP1
uniprot id: A0A8C2SL96
names: Similarity
messages: Belongs to the PP2C family.

93934:MCM4
gene id: 93934:MCM4
uniprot id: A0A8C2TDP0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Chromosome
messages: Component of the MCM2-7 complex.
messages: Nucleus

93934:CD2
gene id: 93934:CD2
uniprot id: A0A8C2SSF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:UHRF1
gene id: 93934:UHRF1
uniprot id: A0A8C2U4K6
names: Subcellular Location Annotation
messages: Nucleus

93934:EIF1B
gene id: 93934:EIF1B
uniprot id: A0A8C2SWZ5
names: Similarity
messages: Belongs to the SUI1 family.

93934:SIX3
gene id: 93934:SIX3
uniprot id: A0A8C2TFU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SIX/Sine oculis homeobox family.
messages: Nucleus

93934:CORO2A
gene id: 93934:CORO2A
uniprot id: A0A8C2SV20
names: Similarity
messages: Belongs to the WD repeat coronin family.

93934:LTA4H
gene id: 93934:LTA4H
uniprot id: A0A8C2SYH7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm

93934:LAMA4
gene id: 93934:LAMA4
uniprot id: A0A8C2TFA0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:EPB42
gene id: 93934:EPB42
uniprot id: A0A8C2STX1
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.

93934:BMPR1A
gene id: 93934:BMPR1A
uniprot id: A0A8C2TK66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:NEFM
gene id: 93934:NEFM
uniprot id: A0A8C2TTU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intermediate filament family.
messages: axon
messages: cytoskeleton

93934:TCN2
gene id: 93934:TCN2
uniprot id: A0A8C2TTK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic cobalamin transport proteins family.
messages: Secreted

93934:FAM234B
gene id: 93934:FAM234B
uniprot id: A0A8C2T9L7
names: Similarity
messages: Belongs to the FAM234 family.

93934:ADAMTS9
gene id: 93934:ADAMTS9
uniprot id: A0A8C2U592
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:FABP6
gene id: 93934:FABP6
uniprot id: A0A8C2Y9J9
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:PALM
gene id: 93934:PALM
uniprot id: A0A8C2TGI6
names: Similarity
messages: Belongs to the paralemmin family.

93934:SPOPL
gene id: 93934:SPOPL
uniprot id: A0A8C2UBM9
names: Similarity
messages: Belongs to the Tdpoz family.

93934:DENND5B
gene id: 93934:DENND5B
uniprot id: A0A8C2UAA3
uniprot id: A0A8C2UAM9
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ASF1A
gene id: 93934:ASF1A
uniprot id: A0A8C2TCA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ASF1 family.
messages: Nucleus

93934:MSH6
gene id: 93934:MSH6
uniprot id: A0A8C2SNQ3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

93934:LHX8
gene id: 93934:LHX8
uniprot id: A0A8C2TRL4
names: Subcellular Location Annotation
messages: Nucleus

93934:LOX
gene id: 93934:LOX
uniprot id: A0A8C2T1J2
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

93934:PITRM1
gene id: 93934:PITRM1
uniprot id: A0A8C2SV45
names: Subunit
messages: Monomer and homodimer; homodimerization is induced by binding of the substrate.

93934:P4HA2
gene id: 93934:P4HA2
uniprot id: A0A8C2UFU7
uniprot id: A0A8C2UGS1
uniprot id: A0A8C2UIT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

93934:GPR132
gene id: 93934:GPR132
uniprot id: A0A8C2Y652
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:TMEM186
gene id: 93934:TMEM186
uniprot id: A0A8C2U1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM186 family.
messages: Membrane

93934:LOC107316916
gene id: 93934:LOC107316916
uniprot id: A0A8C2TQL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

93934:NIBAN1
gene id: 93934:NIBAN1
uniprot id: A0A8C2UKS0
names: Similarity
messages: Belongs to the Niban family.

93934:SMC5
gene id: 93934:SMC5
uniprot id: A0A8C2Y8W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Chromosome
messages: Nucleus

93934:PDHX
gene id: 93934:PDHX
uniprot id: A0A8C2TUR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

93934:HOXD4
gene id: 93934:HOXD4
uniprot id: A0A8C2U3K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:LHFPL6
gene id: 93934:LHFPL6
uniprot id: A0A8C2UB91
names: Subcellular Location Annotation
messages: Membrane

93934:DDX47
gene id: 93934:DDX47
uniprot id: A0A8C2TBH3
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

93934:RELL2
gene id: 93934:RELL2
uniprot id: A0A8C2TGT1
names: Similarity
messages: Belongs to the RELT family.

93934:HACL1
gene id: 93934:HACL1
uniprot id: A0A8C2TK32
names: Similarity
messages: Belongs to the TPP enzyme family.

93934:RBP4
gene id: 93934:RBP4
uniprot id: A0A8C2U6M3
uniprot id: A0A8C2UAY2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

93934:DRAXIN
gene id: 93934:DRAXIN
uniprot id: A0A8C2T259
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the draxin family.
messages: Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord.
messages: Secreted

93934:SMG8
gene id: 93934:SMG8
uniprot id: A0A8C2U5A4
names: Function
names: Similarity
messages: Belongs to the SMG8 family.
messages: Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.

93934:LOC107315884
gene id: 93934:LOC107315884
uniprot id: A0A8C2U806
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

93934:MTX2
gene id: 93934:MTX2
uniprot id: A0A8C2U7D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metaxin family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:JPH1
gene id: 93934:JPH1
uniprot id: A0A8C2TKD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the junctophilin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.
messages: Membrane

93934:SMU1
gene id: 93934:SMU1
uniprot id: A0A8C2SWQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SMU1 family.
messages: Nucleus speckle

93934:GJA9
gene id: 93934:GJA9
uniprot id: A0A8C2U228
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:FAM131B
gene id: 93934:FAM131B
uniprot id: A0A8C2U109
names: Similarity
messages: Belongs to the FAM131 family.

93934:DIS3L
gene id: 93934:DIS3L
uniprot id: A0A8C2UGN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNR ribonuclease family.
messages: Cytoplasm

93934:PFN2
gene id: 93934:PFN2
uniprot id: A0A8C2U8Y2
names: Function
names: Similarity
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

93934:TDRD9
gene id: 93934:TDRD9
uniprot id: A0A8C2STI1
uniprot id: A0A8C2Y5U0
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily.

93934:ATG7
gene id: 93934:ATG7
uniprot id: A0A8C2TLR1
uniprot id: A0A8C2TNY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG7 family.
messages: Cytoplasm
messages: E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Modulates p53/TP53 activity to regulate cell cycle and survival during metabolic stress.
messages: Homodimer.
messages: Preautophagosomal structure

93934:RPL10
gene id: 93934:RPL10
uniprot id: A0A8C2YG28
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

93934:FGF23
gene id: 93934:FGF23
uniprot id: A0A8C2YE97
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:LOC107310250
gene id: 93934:LOC107310250
uniprot id: A9CQL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

93934:PRIM2
gene id: 93934:PRIM2
uniprot id: A0A8C2Y8M4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.

93934:PDIA4
gene id: 93934:PDIA4
uniprot id: A0A8C2TVT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

93934:HAUS3
gene id: 93934:HAUS3
uniprot id: A0A8C2SN97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS3 family.
messages: spindle

93934:HOXD3
gene id: 93934:HOXD3
uniprot id: A0A8C2U6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:PDHA1
gene id: 93934:PDHA1
uniprot id: A0A8C2YFB9
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.

93934:AHSA2P
gene id: 93934:AHSA2P
uniprot id: A0A8C2TZL7
names: Similarity
messages: Belongs to the AHA1 family.

93934:LPAR5
gene id: 93934:LPAR5
uniprot id: A0A8C2U438
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:AURKA
gene id: 93934:AURKA
uniprot id: A0A8C2T3J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: centrosome

93934:EIF2S2
gene id: 93934:EIF2S2
uniprot id: A0A8C2UBU5
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

93934:CAMK4
gene id: 93934:CAMK4
uniprot id: A0A8C2Y9Y0
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:ATP6V0E1
gene id: 93934:ATP6V0E1
uniprot id: A0A8C2T8L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

93934:DUS4L
gene id: 93934:DUS4L
uniprot id: A0A8C2T2M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

93934:HAUS1
gene id: 93934:HAUS1
uniprot id: A0A8C2Y7D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAUS1 family.
messages: spindle

93934:ST8SIA1
gene id: 93934:ST8SIA1
uniprot id: A0A8C2SS18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:FGFR4
gene id: 93934:FGFR4
uniprot id: A0A8C2TG50
uniprot id: A0A8C2TJC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

93934:MAPRE1
gene id: 93934:MAPRE1
uniprot id: Q66T82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPRE family.
messages: Golgi apparatus
messages: Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. Involved in mitotic spindle positioning by stabilizing microtubules and promoting dynamic connection between astral microtubules and the cortex during mitotic chromosome segregation.
messages: centrosome
messages: cytoskeleton
messages: spindle
messages: spindle pole

93934:NOS1
gene id: 93934:NOS1
uniprot id: A0A8C2TXG7
uniprot id: A0A8C2YDW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.
messages: dendritic spine
messages: sarcolemma

93934:APPL2
gene id: 93934:APPL2
uniprot id: A0A8C2U9B2
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Nucleus
messages: phagosome
messages: ruffle

93934:RPL7
gene id: 93934:RPL7
uniprot id: A0A8C2THS4
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

93934:LOC107310350
gene id: 93934:LOC107310350
uniprot id: A0A8C2SQH0
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:GNG2
gene id: 93934:GNG2
uniprot id: A0A8C2YB58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:PTP4A1
gene id: 93934:PTP4A1
uniprot id: A0A8C2Y8H6
names: Subcellular Location Annotation
messages: Early endosome
messages: Endosome

93934:TAF5L
gene id: 93934:TAF5L
uniprot id: A0A8C2SU32
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

93934:VIM
gene id: 93934:VIM
uniprot id: A0A8C2SZM3
names: Function
names: Similarity
messages: Belongs to the intermediate filament family.
messages: Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.

93934:DCAF10
gene id: 93934:DCAF10
uniprot id: A0A8C2T421
names: Function
names: Similarity
messages: Belongs to the WD repeat DCAF10 family.
messages: May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.

93934:ANO3
gene id: 93934:ANO3
uniprot id: A0A8C2TYJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Membrane

93934:RPS6KA5
gene id: 93934:RPS6KA5
uniprot id: A0A8C2SKW6
uniprot id: A0A8C2SNU6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

93934:AADAC
gene id: 93934:AADAC
uniprot id: A0A8C2U3B7
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

93934:GRHL3
gene id: 93934:GRHL3
uniprot id: A0A8C2Y750
names: Subcellular Location Annotation
messages: Nucleus

93934:DEUP1
gene id: 93934:DEUP1
uniprot id: A0A8C2SYI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP63 family.
messages: Cytoplasm

93934:THUMPD3
gene id: 93934:THUMPD3
uniprot id: A0A8C2UGU8
names: Similarity
messages: Belongs to the methyltransferase superfamily.

93934:MMAA
gene id: 93934:MMAA
uniprot id: A0A8C2SSC1
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.

93934:LCMT1
gene id: 93934:LCMT1
uniprot id: A0A8C2YAB4
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

93934:THBS4
gene id: 93934:THBS4
uniprot id: A0A8C2TBG9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:FAM214B
gene id: 93934:FAM214B
uniprot id: A0A8C2T223
names: Similarity
messages: Belongs to the FAM214 family.

93934:TSTA3
gene id: 93934:TSTA3
uniprot id: A0A8C2TI77
names: Function
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.
messages: Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.

93934:TUB
gene id: 93934:TUB
uniprot id: A0A8C2Y6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

93934:PAN3
gene id: 93934:PAN3
uniprot id: A0A8C2UEX7
uniprot id: A0A8C2UGZ4
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PABPC1 (via PABC domain), conferring substrate specificity of the enzyme complex. Interacts with the GW182 family proteins TNRC6A, TNRC6B and TNRC6C.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: P-body
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in general and miRNA-mediated mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein (PABP). PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and PABP, and to miRNA targets via its interaction with GW182 family proteins.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

93934:GJD4
gene id: 93934:GJD4
uniprot id: A0A8C2STN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:IRF4
gene id: 93934:IRF4
uniprot id: A0A8C2YDV5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:MCM2
gene id: 93934:MCM2
uniprot id: A0A8C2TQ08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

93934:CAPRIN2
gene id: 93934:CAPRIN2
uniprot id: A0A8C2UFY9
names: Similarity
messages: Belongs to the caprin family.

93934:GLP1R
gene id: 93934:GLP1R
uniprot id: A0A8C2TFR8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:TSHR
gene id: 93934:TSHR
uniprot id: A0A8C2YGD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: Membrane
messages: Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism.

93934:TFEC
gene id: 93934:TFEC
uniprot id: A0A8C2TJ17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

93934:SLC4A7
gene id: 93934:SLC4A7
uniprot id: A0A8C2TKX3
uniprot id: A0A8C2TNI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

93934:RER1
gene id: 93934:RER1
uniprot id: A0A8C2TD68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

93934:PCID2
gene id: 93934:PCID2
uniprot id: A0A8C2TUQ3
names: Similarity
messages: Belongs to the CSN12 family.

93934:HOXD10
gene id: 93934:HOXD10
uniprot id: A0A8C2U282
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

93934:ADRA1D
gene id: 93934:ADRA1D
uniprot id: A0A8C2T4A6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FLNA (via filamin repeat 21); increases PKA-mediated phosphorylation of FLNA.
messages: Membrane
messages: This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium.

93934:LOC107308400
gene id: 93934:LOC107308400
uniprot id: A0A8C2SUE0
names: Similarity
messages: Belongs to the peptidase M10A family.

93934:RAB18
gene id: 93934:RAB18
uniprot id: A0A8C2SWU2
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Cell membrane
messages: Lipid droplet

93934:B3GALNT2
gene id: 93934:B3GALNT2
uniprot id: A0A8C2SPS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:TLCD4
gene id: 93934:TLCD4
uniprot id: A0A8C2SKZ3
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107309199
gene id: 93934:LOC107309199
uniprot id: A0A8C2SKY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCO1/2 family.
messages: Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2. Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2.
messages: Homodimer.
messages: Mitochondrion inner membrane

93934:SLC11A1
gene id: 93934:SLC11A1
uniprot id: B7SSJ9
names: Similarity
messages: Belongs to the NRAMP family.

93934:LOC107324766
gene id: 93934:LOC107324766
uniprot id: A0A8C2T9W7
names: Similarity
messages: Belongs to the peptidase A1 family.

93934:LOC107325182
gene id: 93934:LOC107325182
uniprot id: A0A8C2SZG7
names: Similarity
messages: Belongs to the intermediate filament family.

93934:TMEM121
gene id: 93934:TMEM121
uniprot id: A0A8C2UG74
names: Similarity
messages: Belongs to the TMEM121 family.

93934:RAB5IF
gene id: 93934:RAB5IF
uniprot id: A0A8C2U821
names: Subcellular Location Annotation
messages: Membrane

93934:NXN
gene id: 93934:NXN
uniprot id: A0A8C2U1C5
names: Similarity
messages: Belongs to the nucleoredoxin family.

93934:SNRNP200
gene id: 93934:SNRNP200
uniprot id: A0A8C2TI57
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

93934:MOV10
gene id: 93934:MOV10
uniprot id: A0A8C2U223
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily.
messages: P-body

93934:ORC1
gene id: 93934:ORC1
uniprot id: A0A8C2TIX1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

93934:CHAF1B
gene id: 93934:CHAF1B
uniprot id: A0A8C2T5C9
names: Subcellular Location Annotation
messages: Nucleus

93934:ERC1
gene id: 93934:ERC1
uniprot id: A0A8C2UCP6
uniprot id: A0A8C2UDU9
names: Subcellular Location Annotation
messages: Cytoplasm

93934:POLH
gene id: 93934:POLH
uniprot id: A0A8C2TK17
names: Subcellular Location Annotation
messages: Nucleus

93934:NR1D2
gene id: 93934:NR1D2
uniprot id: A0A8C2TQG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:TRPM5
gene id: 93934:TRPM5
uniprot id: A0A8C2UAA2
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107320035
gene id: 93934:LOC107320035
uniprot id: A0A8C2UGE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

93934:SLC2A13
gene id: 93934:SLC2A13
uniprot id: A0A8C2Y8G4
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

93934:ADD2
gene id: 93934:ADD2
uniprot id: A0A8C2TI55
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

93934:CCNA1
gene id: 93934:CCNA1
uniprot id: A0A8C2YGR6
names: Similarity
messages: Belongs to the cyclin family. Cyclin AB subfamily.

93934:B4GALT6
gene id: 93934:B4GALT6
uniprot id: A0A8C2THA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

93934:KIF25
gene id: 93934:KIF25
uniprot id: A0A8C2Y6E9
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:ZDHHC6
gene id: 93934:ZDHHC6
uniprot id: A0A8C2U9H7
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:EEF1AKMT1
gene id: 93934:EEF1AKMT1
uniprot id: A0A8C2SPM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79'.
messages: Was originally thought to be an N(6)-adenine-specific DNA methyltransferase based on primary sequence and predicted secondary structure.

93934:TLE1
gene id: 93934:TLE1
uniprot id: A0A8C2TAP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat Groucho/TLE family.
messages: Nucleus

93934:TARDBP
gene id: 93934:TARDBP
uniprot id: A0A8C2TYC0
names: Subcellular Location Annotation
messages: Nucleus

93934:GRIN1
gene id: 93934:GRIN1
uniprot id: A0A8C2TVN2
uniprot id: A0A8C2TW95
uniprot id: A0A8C2TY56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR1/GRIN1 subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:DRD1
gene id: 93934:DRD1
uniprot id: A0A8C2TBR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SRD5A1
gene id: 93934:SRD5A1
uniprot id: A0A8C2TSL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

93934:VTI1A
gene id: 93934:VTI1A
uniprot id: A0A8C2YGU4
uniprot id: A0A8C2YGV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

93934:THBS2
gene id: 93934:THBS2
uniprot id: A0A8C2SU38
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SLC35A5
gene id: 93934:SLC35A5
uniprot id: A0A8C2U171
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

93934:LOC107315148
gene id: 93934:LOC107315148
uniprot id: A0A8C2UC75
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:HMCES
gene id: 93934:HMCES
uniprot id: A0A8C2TPY5
names: Function
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.
messages: Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA: forms a stable thiazolidine linkage between a ring-opened abasic site and the alpha-amino and sulfhydryl substituents of its N-terminal catalytic cysteine residue. The HMCES DNA-protein cross-link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endonucleases that are error-prone and would generate mutations and double-strand breaks. Has preference for ssDNA, but can also accommodate double-stranded DNA with 3' or 5' overhang (dsDNA), and dsDNA-ssDNA 3' junction.

93934:L3HYPDH
gene id: 93934:L3HYPDH
uniprot id: A0A8C2T2J3
names: Similarity
messages: Belongs to the proline racemase family.

93934:CENPH
gene id: 93934:CENPH
uniprot id: A0A8C2Y8X6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-H/MCM16 family.
messages: Nucleus
messages: kinetochore

93934:EXOSC1
gene id: 93934:EXOSC1
uniprot id: A0A8C2UDU3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:SLC17A8
gene id: 93934:SLC17A8
uniprot id: A0A8C2Y8H8
names: Subcellular Location Annotation
messages: Membrane

93934:MINDY3
gene id: 93934:MINDY3
uniprot id: A0A8C2T1G1
uniprot id: A0A8C2T2W7
names: Function
names: Similarity
messages: Belongs to the MINDY deubiquitinase family. FAM188 subfamily.
messages: Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins.

93934:SLC5A8
gene id: 93934:SLC5A8
uniprot id: A0A8C2Y8I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:USP30
gene id: 93934:USP30
uniprot id: A0A8C2T450
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:RGS2
gene id: 93934:RGS2
uniprot id: A0A8C2UDL4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: nucleolus

93934:TPD52L2
gene id: 93934:TPD52L2
uniprot id: A0A8C2SX71
names: Similarity
messages: Belongs to the TPD52 family.

93934:SERPINC1
gene id: 93934:SERPINC1
uniprot id: A0A8C2UH26
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the serpin family.
messages: Forms protease inhibiting heterodimer with TMPRSS7.
messages: extracellular space

93934:PPP2CA
gene id: 93934:PPP2CA
uniprot id: A0A8C2SYS8
names: Similarity
messages: Belongs to the PPP phosphatase family.

93934:ACVR2A
gene id: 93934:ACVR2A
uniprot id: A0A8C2UD60
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:BLK
gene id: 93934:BLK
uniprot id: A0A8C2SPN3
uniprot id: A0A8C2Y4X4
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:RAD1
gene id: 93934:RAD1
uniprot id: A0A8C2T4L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Nucleus

93934:ADAM23
gene id: 93934:ADAM23
uniprot id: A0A8C2TUL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107310621
gene id: 93934:LOC107310621
uniprot id: A0A8C2TEU5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: centrosome
messages: cilium basal body
messages: perinuclear region
messages: spindle

93934:GPRIN3
gene id: 93934:GPRIN3
uniprot id: A0A8C2TBE8
names: Function
messages: May be involved in neurite outgrowth.

93934:FAM221A
gene id: 93934:FAM221A
uniprot id: A0A8C2YBS6
names: Similarity
messages: Belongs to the FAM221 family.

93934:SLC25A36
gene id: 93934:SLC25A36
uniprot id: A0A8C2SZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:LANCL3
gene id: 93934:LANCL3
uniprot id: A0A8C2U4N5
names: Similarity
messages: Belongs to the LanC-like protein family.

93934:SLC35F2
gene id: 93934:SLC35F2
uniprot id: A0A8C2SSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

93934:MPC2
gene id: 93934:MPC2
uniprot id: A0A8C2SQ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

93934:SLC39A3
gene id: 93934:SLC39A3
uniprot id: A0A8C2TIP9
names: Subcellular Location Annotation
messages: Membrane

93934:ALKBH8
gene id: 93934:ALKBH8
uniprot id: A0A8C2SVJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkB family.
messages: Cytoplasm

93934:LOC107310310
gene id: 93934:LOC107310310
uniprot id: A0A8C2SLS0
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93934:MRPS26
gene id: 93934:MRPS26
uniprot id: A0A8C2T6S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS26 family.
messages: Mitochondrion

93934:NCAPD2
gene id: 93934:NCAPD2
uniprot id: A0A8C2TZ37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

93934:SEMA5A
gene id: 93934:SEMA5A
uniprot id: A0A8C2TY01
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PLPPR5
gene id: 93934:PLPPR5
uniprot id: A0A8C2SLU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

93934:NXPE3
gene id: 93934:NXPE3
uniprot id: A0A8C2U711
names: Similarity
messages: Belongs to the NXPE family.

93934:NRTN
gene id: 93934:NRTN
uniprot id: A0A8C2TDQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family. GDNF subfamily.
messages: Secreted

93934:ITK
gene id: 93934:ITK
uniprot id: A0A8C2TGK7
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:MAP3K13
gene id: 93934:MAP3K13
uniprot id: A0A8C2YG89
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

93934:FABP2
gene id: 93934:FABP2
uniprot id: A0A1L5SA92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytoplasm

93934:IAH1
gene id: 93934:IAH1
uniprot id: A0A8C2TIG4
names: Function
names: Similarity
messages: Belongs to the 'GDSL' lipolytic enzyme family. IAH1 subfamily.
messages: Probable lipase.

93934:DACT1
gene id: 93934:DACT1
uniprot id: A0A8C2Y7G0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dapper family.
messages: Cytoplasm

93934:ONECUT2
gene id: 93934:ONECUT2
uniprot id: A0A8C2SWT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

93934:SSBP2
gene id: 93934:SSBP2
uniprot id: A0A8C2SP17
names: Subcellular Location Annotation
messages: Nucleus

93934:MAD1L1
gene id: 93934:MAD1L1
uniprot id: A0A8C2TSX9
uniprot id: A0A8C2TTZ2
uniprot id: A0A8C2TVL4
uniprot id: A0A8C2YCZ7
names: Similarity
messages: Belongs to the MAD1 family.

93934:FGF3
gene id: 93934:FGF3
uniprot id: A0A8C2U3H9
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:LOC107306401
gene id: 93934:LOC107306401
uniprot id: A0A8C2TIL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:WNT9A
gene id: 93934:WNT9A
uniprot id: A0A8C2YAN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:HEPH
gene id: 93934:HEPH
uniprot id: A0A8C2STJ0
names: Similarity
messages: Belongs to the multicopper oxidase family.

93934:NACC2
gene id: 93934:NACC2
uniprot id: A0A8C2T7A8
names: Subcellular Location Annotation
messages: Nucleus

93934:RAX
gene id: 93934:RAX
uniprot id: A0A8C2SY79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

93934:SAP30
gene id: 93934:SAP30
uniprot id: A0A8C2YA93
names: Similarity
messages: Belongs to the SAP30 family.

93934:NCOA3
gene id: 93934:NCOA3
uniprot id: A0A8C2SQS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRC/p160 nuclear receptor coactivator family.
messages: Nucleus

93934:CAPN14
gene id: 93934:CAPN14
uniprot id: A0A8C2SN38
uniprot id: A0A8C2Y5E6
names: Similarity
messages: Belongs to the peptidase C2 family.

93934:NR2C1
gene id: 93934:NR2C1
uniprot id: A0A8C2Y788
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:UBALD1
gene id: 93934:UBALD1
uniprot id: A0A8C2TYC6
names: Similarity
messages: Belongs to the UBALD family.

93934:PDE1B
gene id: 93934:PDE1B
uniprot id: A0A8C2UBZ6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:ELF2
gene id: 93934:ELF2
uniprot id: A0A8C2SPR7
uniprot id: A0A8C2SRM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:CSNK1G2
gene id: 93934:CSNK1G2
uniprot id: A0A8C2TDD9
uniprot id: A0A8C2TH38
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

93934:CCZ1
gene id: 93934:CCZ1
uniprot id: A0A8C2TNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCZ1 family.
messages: Lysosome membrane

93934:LOC107309443
gene id: 93934:LOC107309443
uniprot id: A0A8C2TVC3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:TMPRSS2
gene id: 93934:TMPRSS2
uniprot id: A0A8C2TAL7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ARAP3
gene id: 93934:ARAP3
uniprot id: A0A8C2TGQ5
uniprot id: A0A8C2YB74
names: Subcellular Location Annotation
messages: Cytoplasm

93934:GABBR2
gene id: 93934:GABBR2
uniprot id: A0A8C2YDA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

93934:HOXB9
gene id: 93934:HOXB9
uniprot id: A0A8C2UCS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

93934:MAPK6
gene id: 93934:MAPK6
uniprot id: A0A8C2U9V6
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.

93934:LOC107312528
gene id: 93934:LOC107312528
uniprot id: A0A8C2SSN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

93934:TOP3B
gene id: 93934:TOP3B
uniprot id: A0A8C2YG47
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

93934:LYPLA2
gene id: 93934:LYPLA2
uniprot id: A0A8C2Y7B2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.

93934:LOC107314871
gene id: 93934:LOC107314871
uniprot id: A0A8C2TT13
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

93934:PXMP4
gene id: 93934:PXMP4
uniprot id: A0A8C2UFR4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Interacts with PEX19.
messages: Peroxisome membrane

93934:PIGL
gene id: 93934:PIGL
uniprot id: A0A8C2TVW0
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

93934:CCNT2
gene id: 93934:CCNT2
uniprot id: A0A8C2UBZ8
uniprot id: A0A8C2UGY1
names: Similarity
messages: Belongs to the cyclin family.

93934:GDF2
gene id: 93934:GDF2
uniprot id: A0A8C2UAZ5
names: Similarity
messages: Belongs to the TGF-beta family.

93934:LOC107320877
gene id: 93934:LOC107320877
uniprot id: A0A8C2TZ90
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:DGKB
gene id: 93934:DGKB
uniprot id: A0A8C2THW8
uniprot id: A0A8C2TIB7
uniprot id: A0A8C2TIJ6
uniprot id: A0A8C2TKL1
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

93934:CHRM3
gene id: 93934:CHRM3
uniprot id: A0A8C2YCP1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

93934:DNMT3B
gene id: 93934:DNMT3B
uniprot id: A0A8C2SZZ6
names: Subcellular Location Annotation
messages: Nucleus

93934:IRAK1BP1
gene id: 93934:IRAK1BP1
uniprot id: A0A8C2Y7E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRAK1BP1 family.
messages: Cytoplasm
messages: Nucleus

93934:PLPP2
gene id: 93934:PLPP2
uniprot id: A0A8C2TE64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

93934:GNG12
gene id: 93934:GNG12
uniprot id: A0A8C2TV39
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:HTR7
gene id: 93934:HTR7
uniprot id: A0A8C2UBH5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:CDX2
gene id: 93934:CDX2
uniprot id: A0A8C2UH10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Caudal homeobox family.
messages: Nucleus

93934:PDE7A
gene id: 93934:PDE7A
uniprot id: A0A8C2TK02
uniprot id: A0A8C2YBC1
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:FZD10
gene id: 93934:FZD10
uniprot id: A0A8C2YGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Membrane

93934:LRP6
gene id: 93934:LRP6
uniprot id: A0A8C2TZM1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LDLR family.
messages: Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes.
messages: Homodimer; disulfide-linked. Forms phosphorylated oligomer aggregates on Wnt-signaling.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PPM1G
gene id: 93934:PPM1G
uniprot id: A0A8C2TIS1
names: Similarity
messages: Belongs to the PP2C family.

93934:POMT2
gene id: 93934:POMT2
uniprot id: A0A8C2U9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

93934:MFSD10
gene id: 93934:MFSD10
uniprot id: A0A8C2U8X3
names: Subcellular Location Annotation
messages: Membrane

93934:FZD6
gene id: 93934:FZD6
uniprot id: A0A8C2SPY4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasmic vesicle membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TBX3
gene id: 93934:TBX3
uniprot id: A0A8C2TV13
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:GALK2
gene id: 93934:GALK2
uniprot id: A0A8C2UAA7
names: Similarity
messages: Belongs to the GHMP kinase family. GalK subfamily.

93934:EPHA7
gene id: 93934:EPHA7
uniprot id: A0A8C2SQ09
uniprot id: A0A8C2SQ13
uniprot id: A0A8C2SS77
names: Subcellular Location Annotation
messages: Membrane

93934:LGMN
gene id: 93934:LGMN
uniprot id: A0A8C2SRJ3
names: Similarity
messages: Belongs to the peptidase C13 family.

93934:STAG2
gene id: 93934:STAG2
uniprot id: A0A8C2UB08
uniprot id: A0A8C2YFZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCC3 family.
messages: Chromosome
messages: Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate.
messages: Nucleus
messages: Part of the cohesin complex which is composed of a heterodimer between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached via their hinge domain, and RAD21 which link them at their heads, and one STAG protein.
messages: centromere

93934:GIMD1
gene id: 93934:GIMD1
uniprot id: A0A8C2TB72
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family. IAN subfamily.

93934:MFSD6
gene id: 93934:MFSD6
uniprot id: A0A8C2TSK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. MFSD6 family.
messages: Membrane

93934:TAT
gene id: 93934:TAT
uniprot id: A0A8C2SXW3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.

93934:TSPAN15
gene id: 93934:TSPAN15
uniprot id: A0A8C2T765
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:LOC107324999
gene id: 93934:LOC107324999
uniprot id: A0A8C2U8P9
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:WNT2B
gene id: 93934:WNT2B
uniprot id: A0A8C2YEJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:FBN2
gene id: 93934:FBN2
uniprot id: A0A8C2TNA5
uniprot id: A0A8C2YBX6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fibrillin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:SOX12
gene id: 93934:SOX12
uniprot id: A0A8C2T1J0
names: Subcellular Location Annotation
messages: Nucleus

93934:SLC16A1
gene id: 93934:SLC16A1
uniprot id: A0A8C2U187
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cell membrane
messages: Membrane
messages: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Depending on the tissue and on cicumstances, mediates the import or export of lactic acid and ketone bodies. Required for normal nutrient assimilation, increase of white adipose tissue and body weight gain when on a high-fat diet. Plays a role in cellular responses to a high-fat diet by modulating the cellular levels of lactate and pyruvate, small molecules that contribute to the regulation of central metabolic pathways and insulin secretion, with concomitant effects on plasma insulin levels and blood glucose homeostasis.

93934:RAF1
gene id: 93934:RAF1
uniprot id: A0A8C2TLC3
uniprot id: A0A8C2TNY9
uniprot id: A0A8C2YC14
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.

93934:ADGRB3
gene id: 93934:ADGRB3
uniprot id: A0A8C2T3H4
names: Subcellular Location Annotation
messages: Membrane

93934:FAM98B
gene id: 93934:FAM98B
uniprot id: A0A8C2U0M3
uniprot id: A0A8C2U3L1
names: Similarity
messages: Belongs to the FAM98 family.

93934:LACTB2
gene id: 93934:LACTB2
uniprot id: A0A8C2TL20
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Endoribonuclease; cleaves preferentially 3' to purine-pyrimidine dinucleotide motifs in single-stranded RNA. The cleavage product contains a free 3' -OH group. Has no activity with double-stranded RNA or DNA. Required for normal mitochondrial function and cell viability.

93934:SMAD2
gene id: 93934:SMAD2
uniprot id: A0A8C2SYA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:CHPT1
gene id: 93934:CHPT1
uniprot id: A0A8C2UCY3
uniprot id: A0A8C2UGK4
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

93934:CGAS
gene id: 93934:CGAS
uniprot id: A0A8C2T6G9
names: Similarity
messages: Belongs to the mab-21 family.

93934:PAPPA2
gene id: 93934:PAPPA2
uniprot id: A0A8C2YHT1
names: Caution
names: Similarity
messages: Belongs to the peptidase M43B family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107306278
gene id: 93934:LOC107306278
uniprot id: A0A8C2TCI3
names: Similarity
messages: Belongs to the FBPase class 1 family.

93934:LOC107325706
gene id: 93934:LOC107325706
uniprot id: A0A8C2UB95
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion membrane

93934:LFNG
gene id: 93934:LFNG
uniprot id: A0A8C2YCZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:C9H3orf70
gene id: 93934:C9H3orf70
uniprot id: A0A8C2U6N2
names: Similarity
messages: Belongs to the UPF0524 family.

93934:RDH5
gene id: 93934:RDH5
uniprot id: A0A8C2ST03
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:RP2
gene id: 93934:RP2
uniprot id: A0A8C2U5N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
messages: Belongs to the TBCC family.
messages: Cell membrane
messages: Membrane

93934:NMNAT1
gene id: 93934:NMNAT1
uniprot id: A0A8C2TKK6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

93934:MRPL14
gene id: 93934:MRPL14
uniprot id: A0A8C2TLC9
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

93934:KDR
gene id: 93934:KDR
uniprot id: A0A8C2TEI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

93934:CKS2
gene id: 93934:CKS2
uniprot id: A0A8C2Y9W3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.
messages: Forms a homohexamer that can probably bind six kinase subunits.

93934:WDPCP
gene id: 93934:WDPCP
uniprot id: A0A8C2THY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat fritz family.
messages: Cell membrane
messages: Membrane
messages: cilium axoneme

93934:DNAJB12
gene id: 93934:DNAJB12
uniprot id: A0A8C2TBI8
names: Subcellular Location Annotation
messages: Membrane

93934:ANAPC10
gene id: 93934:ANAPC10
uniprot id: A0A8C2SP80
names: Function
names: Similarity
messages: Belongs to the APC10 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.

93934:LOC107312862
gene id: 93934:LOC107312862
uniprot id: A0A8C2U516
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

93934:PIGK
gene id: 93934:PIGK
uniprot id: A0A8C2TBK2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase C13 family.
messages: Forms a complex with PIGT, PIGS, PIGU and GAA1.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

93934:CHMP2B
gene id: 93934:CHMP2B
uniprot id: A0A8C2SVS9
names: Similarity
messages: Belongs to the SNF7 family.

93934:HTR1A
gene id: 93934:HTR1A
uniprot id: A0A8C2ST67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:GRM3
gene id: 93934:GRM3
uniprot id: A0A8C2SWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 3 family.
messages: Cell membrane
messages: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
messages: Interacts with TAMALIN.
messages: Membrane

93934:SNRPD1
gene id: 93934:SNRPD1
uniprot id: A0A8C2SVF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: Plays a role in pre-mRNA splicing as a core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome.

93934:RNF13
gene id: 93934:RNF13
uniprot id: A0A8C2UAG0
names: Subcellular Location Annotation
messages: Membrane

93934:BLOC1S5
gene id: 93934:BLOC1S5
uniprot id: A0A8C2U035
names: Function
names: Similarity
messages: Belongs to the BLOC1S5 family.
messages: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO).

93934:MRPS14
gene id: 93934:MRPS14
uniprot id: A0A8C2UK01
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

93934:ALG6
gene id: 93934:ALG6
uniprot id: A0A8C2TVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107325550
gene id: 93934:LOC107325550
uniprot id: A0A8C2TH89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane

93934:TNFRSF19
gene id: 93934:TNFRSF19
uniprot id: A0A8C2SQ25
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MLNR
gene id: 93934:MLNR
uniprot id: A0A8C2UB00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:ELOVL2
gene id: 93934:ELOVL2
uniprot id: A0A8C2U2J4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL2 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production of polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

93934:TNFSF15
gene id: 93934:TNFSF15
uniprot id: A0A8C2UBE5
names: Similarity
messages: Belongs to the tumor necrosis factor family.

93934:GPR6
gene id: 93934:GPR6
uniprot id: A0A8C2TFV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SLC16A7
gene id: 93934:SLC16A7
uniprot id: A0A8C2YCI6
names: Similarity
names: Subcellular Location Annotation
messages: Basolateral cell membrane
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Cytoplasm
messages: Membrane

93934:EIF4EBP1
gene id: 93934:EIF4EBP1
uniprot id: A0A8C2TU20
names: Similarity
messages: Belongs to the eIF4E-binding protein family.

93934:HS2ST1
gene id: 93934:HS2ST1
uniprot id: A0A8C2T787
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

93934:LOC107318142
gene id: 93934:LOC107318142
uniprot id: A0A8C2TPX2
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:SENP7
gene id: 93934:SENP7
uniprot id: A0A8C2U479
names: Similarity
messages: Belongs to the peptidase C48 family.

93934:USP45
gene id: 93934:USP45
uniprot id: A0A8C2SK31
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:CALHM4
gene id: 93934:CALHM4
uniprot id: A0A8C2TCW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

93934:LOC107305742
gene id: 93934:LOC107305742
uniprot id: A0A8C2Y7C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93934:NUDC
gene id: 93934:NUDC
uniprot id: A0A8C2TZT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nudC family.
messages: Midbody
messages: spindle

93934:SQLE
gene id: 93934:SQLE
uniprot id: A0A8C2T063
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane

93934:IGF1R
gene id: 93934:IGF1R
uniprot id: A6P6W3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

93934:UTP11
gene id: 93934:UTP11
uniprot id: A0A8C2TXS7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

93934:SPHKAP
gene id: 93934:SPHKAP
uniprot id: A0A8C2Y8Z0
names: Similarity
messages: Belongs to the AKAP110 family.

93934:SLC35F1
gene id: 93934:SLC35F1
uniprot id: A0A8C2TBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC35F solute transporter family.
messages: Membrane

93934:PNKD
gene id: 93934:PNKD
uniprot id: A0A8C2YCA2
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

93934:SLC25A15
gene id: 93934:SLC25A15
uniprot id: A0A8C2UB82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:HSPH1
gene id: 93934:HSPH1
uniprot id: A0A8C2YH52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Cytoplasm

93934:SLC2A2
gene id: 93934:SLC2A2
uniprot id: A0A8C2U6I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
messages: Cell membrane
messages: Membrane

93934:USP44
gene id: 93934:USP44
uniprot id: A0A8C2T1K4
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:PRPS2
gene id: 93934:PRPS2
uniprot id: A0A8C2U3I3
uniprot id: A0A8C2U3U7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family.
messages: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis.
messages: Homodimer. The active form is probably a hexamer composed of 3 homodimers.

93934:ERG28
gene id: 93934:ERG28
uniprot id: A0A8C2UBA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:SDHAF3
gene id: 93934:SDHAF3
uniprot id: A0A8C2TH42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

93934:SERINC5
gene id: 93934:SERINC5
uniprot id: A0A8C2T8J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Cell membrane
messages: Membrane

93934:ADPRS
gene id: 93934:ADPRS
uniprot id: A0A8C2U057
names: Similarity
messages: Belongs to the ADP-ribosylglycohydrolase family.

93934:LOC107307962
gene id: 93934:LOC107307962
uniprot id: A0A8C2TYZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

93934:OTC
gene id: 93934:OTC
uniprot id: A0A8C2YEQ0
names: Similarity
names: Subunit
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
messages: Homotrimer.

93934:NTRK2
gene id: 93934:NTRK2
uniprot id: A0A8C2TD39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

93934:LOC107319025
gene id: 93934:LOC107319025
uniprot id: A0A8C2TYY3
names: Similarity
messages: Belongs to the cystatin family.

93934:TJP2
gene id: 93934:TJP2
uniprot id: A0A8C2T5G1
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: tight junction

93934:TRRAP
gene id: 93934:TRRAP
uniprot id: A0A8C2TPT2
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. TRA1 subfamily.

93934:TSPAN9
gene id: 93934:TSPAN9
uniprot id: A0A8C2U115
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:LOC107322561
gene id: 93934:LOC107322561
uniprot id: A0A8C2U0Q0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:SYNPR
gene id: 93934:SYNPR
uniprot id: A0A8C2U4Q5
uniprot id: A0A8C2U571
uniprot id: A0A8C2U6J4
uniprot id: A0A8C2U811
uniprot id: A0A8C2U8H7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptophysin/synaptobrevin family.
messages: Membrane

93934:GGT1
gene id: 93934:GGT1
uniprot id: A0A8C2TEK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

93934:KNG1
gene id: 93934:KNG1
uniprot id: A0A8C2TP66
names: Subcellular Location Annotation
messages: extracellular space

93934:LOC107308953
gene id: 93934:LOC107308953
uniprot id: A0A8C2SY81
names: Similarity
messages: Belongs to the SELO family.

93934:NSUN6
gene id: 93934:NSUN6
uniprot id: A0A8C2SV19
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

93934:STAM2
gene id: 93934:STAM2
uniprot id: A0A8C2UH61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

93934:EXOC3L4
gene id: 93934:EXOC3L4
uniprot id: A0A8C2SR54
names: Similarity
messages: Belongs to the SEC6 family.

93934:TSHZ3
gene id: 93934:TSHZ3
uniprot id: A0A8C2TRP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.
messages: Nucleus

93934:ORC5
gene id: 93934:ORC5
uniprot id: A0A8C2T2P3
names: Subcellular Location Annotation
messages: Nucleus

93934:EAF1
gene id: 93934:EAF1
uniprot id: A0A8C2TL90
names: Similarity
messages: Belongs to the EAF family.

93934:PRKCZ
gene id: 93934:PRKCZ
uniprot id: A0A8C2TCX1
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

93934:TMOD1
gene id: 93934:TMOD1
uniprot id: A0A8C2STK2
names: Subcellular Location Annotation
messages: cytoskeleton

93934:NATD1
gene id: 93934:NATD1
uniprot id: A0A8C2SND2
names: Similarity
messages: Belongs to the NATD1 family.

93934:ZWILCH
gene id: 93934:ZWILCH
uniprot id: A0A8C2UDT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZWILCH family.
messages: Component of the RZZ complex.
messages: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex.
messages: kinetochore

93934:PARD6G
gene id: 93934:PARD6G
uniprot id: A0A8C2T417
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

93934:TSPAN7
gene id: 93934:TSPAN7
uniprot id: A0A8C2YEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:ACAN
gene id: 93934:ACAN
uniprot id: A0A8C2UEP9
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:ANXA11
gene id: 93934:ANXA11
uniprot id: A0A8C2YBY6
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

93934:LOC107309362
gene id: 93934:LOC107309362
uniprot id: A0A8C2SVA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

93934:SLC43A2
gene id: 93934:SLC43A2
uniprot id: A0A8C2TJJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC43A transporter (TC 2.A.1.44) family.
messages: Membrane

93934:ECHDC2
gene id: 93934:ECHDC2
uniprot id: A0A8C2TME0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93934:ADCY8
gene id: 93934:ADCY8
uniprot id: A0A8C2T8P5
uniprot id: A0A8C2T9Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

93934:DRD3
gene id: 93934:DRD3
uniprot id: A0A8C2U3N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation.
messages: Membrane

93934:LOC107325364
gene id: 93934:LOC107325364
uniprot id: A0A8C2TEI1
names: Similarity
messages: Belongs to the actin family.

93934:SLC5A1
gene id: 93934:SLC5A1
uniprot id: A0A8C2TIZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:IARS2
gene id: 93934:IARS2
uniprot id: A0A8C2T6C9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:CEP20
gene id: 93934:CEP20
uniprot id: A0A8C2YDJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP43 family.
messages: cilium basal body

93934:ATP10B
gene id: 93934:ATP10B
uniprot id: A0A8C2TAB5
uniprot id: A0A8C2TAR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:PEX12
gene id: 93934:PEX12
uniprot id: A0A8C2TEF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

93934:LOC107320369
gene id: 93934:LOC107320369
uniprot id: A0A8C2TM16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm

93934:LOC107312863
gene id: 93934:LOC107312863
uniprot id: A0A8C2U215
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:GAP43
gene id: 93934:GAP43
uniprot id: A0A8C2U4V7
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the neuromodulin family.
messages: Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.
messages: Cell membrane
messages: Membrane
messages: Palmitoylated. Palmitoylation is essential for plasma membrane association.
messages: Synapse
messages: This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
messages: filopodium membrane
messages: growth cone membrane

93934:LOC107312844
gene id: 93934:LOC107312844
uniprot id: A0A8C2TZV9
uniprot id: A0A8C2U160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

93934:LOC107320986
gene id: 93934:LOC107320986
uniprot id: A0A8C2TXH8
names: Similarity
messages: Belongs to the globin family.

93934:GTF2H5
gene id: 93934:GTF2H5
uniprot id: A0A8C2Y995
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

93934:PRKX
gene id: 93934:PRKX
uniprot id: A0A8C2U7K9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:HAS2
gene id: 93934:HAS2
uniprot id: A0A8C2T195
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NodC/HAS family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane

93934:ITIH5
gene id: 93934:ITIH5
uniprot id: A0A8C2SXV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

93934:SORCS1
gene id: 93934:SORCS1
uniprot id: A0A8C2UC41
uniprot id: A0A8C2UDB6
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

93934:EZR
gene id: 93934:EZR
uniprot id: A0A8C2TAK8
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

93934:SNX7
gene id: 93934:SNX7
uniprot id: A0A8C2SKH5
names: Similarity
messages: Belongs to the sorting nexin family.

93934:GFRA2
gene id: 93934:GFRA2
uniprot id: A0A8C2TXZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.

93934:WNT11
gene id: 93934:WNT11
uniprot id: A0A8C2SYM9
uniprot id: P51891
names: Developmental Stage
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Expressed during embryogenesis.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters (By similarity).
messages: Palmitoleoylation is required for efficient binding to frizzled receptors. Depalmitoleoylation leads to Wnt signaling pathway inhibition.
messages: extracellular matrix

93934:BDNF
gene id: 93934:BDNF
uniprot id: A0A8C2TTX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NGF-beta family.
messages: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it.
messages: Secreted

93934:SLITRK2
gene id: 93934:SLITRK2
uniprot id: A0A8C2Y4P8
names: Similarity
messages: Belongs to the SLITRK family.

93934:ELOVL4
gene id: 93934:ELOVL4
uniprot id: A0A8C2SVV8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ELO family. ELOVL4 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Oligomer.
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

93934:DCTN6
gene id: 93934:DCTN6
uniprot id: A0A8C2T9D8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynactin subunits 5/6 family. Dynactin subunit 6 subfamily.
messages: cytoskeleton

93934:IDO2
gene id: 93934:IDO2
uniprot id: A0A8C2TTJ3
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

93934:TGFB2
gene id: 93934:TGFB2
uniprot id: A0A8C2T5Z9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively.
messages: extracellular matrix

93934:CHPF2
gene id: 93934:CHPF2
uniprot id: A0A8C2T4J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

93934:TMEM33
gene id: 93934:TMEM33
uniprot id: A0A8C2TZS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

93934:NR3C1
gene id: 93934:NR3C1
uniprot id: A0A8C2UHE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Mitochondrion
messages: Nucleus
messages: centrosome
messages: spindle

93934:SBDS
gene id: 93934:SBDS
uniprot id: A0A8C2SZN1
names: Function
names: Similarity
messages: Belongs to the SDO1/SBDS family.
messages: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation.

93934:HNRNPDL
gene id: 93934:HNRNPDL
uniprot id: A0A8C2TCG1
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:LOC107312840
gene id: 93934:LOC107312840
uniprot id: A0A8C2U0F3
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-5/CLCN5 subfamily.
messages: Cell membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Interacts with NEDD4 and NEDD4L.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:PYROXD1
gene id: 93934:PYROXD1
uniprot id: A0A8C2Y663
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. PYROXD1 subfamily.
messages: sarcomere

93934:MMRN1
gene id: 93934:MMRN1
uniprot id: A0A8C2T9L9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ITGA2
gene id: 93934:ITGA2
uniprot id: A0A8C2THN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

93934:TMEM234
gene id: 93934:TMEM234
uniprot id: A0A8C2SLH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM234 family.
messages: Membrane

93934:CDH7
gene id: 93934:CDH7
uniprot id: A0A8C2T6U9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:HINT1
gene id: 93934:HINT1
uniprot id: Q78DM8
names: Similarity
messages: Belongs to the HINT family.

93934:ADM
gene id: 93934:ADM
uniprot id: A0A8C2Y655
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adrenomedullin family.
messages: Secreted

93934:LOC107313255
gene id: 93934:LOC107313255
uniprot id: A0A8C2Y9I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

93934:BOD1
gene id: 93934:BOD1
uniprot id: A0A8C2Y9E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOD1 family.
messages: centrosome
messages: kinetochore

93934:FAM13A
gene id: 93934:FAM13A
uniprot id: A0A8C2TEG4
uniprot id: A0A8C2Y9P5
names: Similarity
messages: Belongs to the FAM13 family.

93934:POU4F1
gene id: 93934:POU4F1
uniprot id: A0A8C2U9X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

93934:CD99
gene id: 93934:CD99
uniprot id: A0A8C2U967
names: Similarity
messages: Belongs to the CD99 family.

93934:SLC7A1
gene id: 93934:SLC7A1
uniprot id: A0A8C2YH55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family.
messages: Cell membrane
messages: Membrane

93934:PHAX
gene id: 93934:PHAX
uniprot id: A0A8C2TKU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PHAX family.
messages: Cytoplasm

93934:GC
gene id: 93934:GC
uniprot id: A0A8C2SNX0
names: Function
names: Subcellular Location Annotation
messages: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.
messages: Secreted

93934:ORAI1
gene id: 93934:ORAI1
uniprot id: A0A8C2UE80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Orai family.
messages: Membrane

93934:MRPS27
gene id: 93934:MRPS27
uniprot id: A0A8C2SSG2
names: Subcellular Location Annotation
messages: Mitochondrion

93934:LOC107306415
gene id: 93934:LOC107306415
uniprot id: A0A8C2TMH0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

93934:LOC107319130
gene id: 93934:LOC107319130
uniprot id: A0A8C2TKQ6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:MRPL47
gene id: 93934:MRPL47
uniprot id: A0A8C2TU71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

93934:HCRTR2
gene id: 93934:HCRTR2
uniprot id: A0A8C2T7I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SMAD9
gene id: 93934:SMAD9
uniprot id: A0A8C2U9D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:CHMP4C
gene id: 93934:CHMP4C
uniprot id: A0A8C2SJV4
names: Similarity
messages: Belongs to the SNF7 family.

93934:RUNX1
gene id: 93934:RUNX1
uniprot id: A0A8C2T4M5
names: Subcellular Location Annotation
messages: Nucleus

93934:SLC46A3
gene id: 93934:SLC46A3
uniprot id: A0A8C2UFL7
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107320642
gene id: 93934:LOC107320642
uniprot id: A0A8C2Y7D7
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

93934:PPP2CB
gene id: 93934:PPP2CB
uniprot id: A0A8C2T874
names: Similarity
messages: Belongs to the PPP phosphatase family.

93934:ENDOG
gene id: 93934:ENDOG
uniprot id: A0A8C2UAW0
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

93934:DDX1
gene id: 93934:DDX1
uniprot id: A0A8C2TFU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX1 subfamily.
messages: Cytoplasmic granule

93934:LOC107317691
gene id: 93934:LOC107317691
uniprot id: A0A8C2TKK3
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:TRPM2
gene id: 93934:TRPM2
uniprot id: A0A8C2T0J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM2 sub-subfamily.
messages: Cell membrane
messages: Membrane

93934:GSX1
gene id: 93934:GSX1
uniprot id: A0A8C2UFS3
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107305798
gene id: 93934:LOC107305798
uniprot id: A0A8C2T465
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:LOC107322608
gene id: 93934:LOC107322608
uniprot id: A0A8C2SW61
names: Function
names: Similarity
messages: Belongs to the TYW1 family.
messages: Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis.

93934:LOC107309395
gene id: 93934:LOC107309395
uniprot id: A0A8C2Y700
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

93934:TMEM106B
gene id: 93934:TMEM106B
uniprot id: A0A8C2TKA9
names: Similarity
messages: Belongs to the TMEM106 family.

93934:HOXA2
gene id: 93934:HOXA2
uniprot id: A0A8C2TQ95
names: Subcellular Location Annotation
messages: Nucleus

93934:SPI1
gene id: 93934:SPI1
uniprot id: A0A8C2TF75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:PCSK2
gene id: 93934:PCSK2
uniprot id: A0A8C2TK95
names: Similarity
messages: Belongs to the peptidase S8 family.

93934:LOC107313494
gene id: 93934:LOC107313494
uniprot id: A0A8C2SRN9
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:ERGIC3
gene id: 93934:ERGIC3
uniprot id: A0A8C2YH89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

93934:LOC107322294
gene id: 93934:LOC107322294
uniprot id: A0A8C2UHJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:PTGFR
gene id: 93934:PTGFR
uniprot id: A0A8C2TAF7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:PRDM5
gene id: 93934:PRDM5
uniprot id: A0A8C2SW68
uniprot id: A0A8C2SXH2
names: Subcellular Location Annotation
messages: Nucleus

93934:TRAF5
gene id: 93934:TRAF5
uniprot id: A0A8C2T6W8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

93934:DOCK4
gene id: 93934:DOCK4
uniprot id: A0A8C2TMW5
uniprot id: A0A8C2TQD9
uniprot id: A0A8C2YCH0
names: Similarity
messages: Belongs to the DOCK family.

93934:ADCY9
gene id: 93934:ADCY9
uniprot id: A0A8C2U1G3
names: Similarity
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

93934:EMP2
gene id: 93934:EMP2
uniprot id: A0A8C2U0Z3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the PMP-22/EMP/MP20 family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Membrane raft
messages: Nucleus
messages: perinuclear region

93934:LOC107305735
gene id: 93934:LOC107305735
uniprot id: A0A8C2T235
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

93934:PLXNA4
gene id: 93934:PLXNA4
uniprot id: A0A8C2Y6I3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plexin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LOC107325374
gene id: 93934:LOC107325374
uniprot id: A0A8C2T0A7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

93934:LOC107324384
gene id: 93934:LOC107324384
uniprot id: A0A8C2YCX8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:DYDC1
gene id: 93934:DYDC1
uniprot id: A0A8C2TPF2
names: Similarity
messages: Belongs to the dpy-30 family.

93934:ATF7IP
gene id: 93934:ATF7IP
uniprot id: A0A8C2T873
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCAF family.
messages: Nucleus

93934:JUN
gene id: 93934:JUN
uniprot id: A0A8C2TMK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

93934:TRIP13
gene id: 93934:TRIP13
uniprot id: A0A8C2U5N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. PCH2 subfamily.
messages: Nucleus
messages: Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways.

93934:RCAN1
gene id: 93934:RCAN1
uniprot id: A0A8C2T845
names: Similarity
messages: Belongs to the RCAN family.

93934:SUSD6
gene id: 93934:SUSD6
uniprot id: A0A8C2TVS6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:DNAJA1
gene id: 93934:DNAJA1
uniprot id: A0A8C2Y6H5
names: Subcellular Location Annotation
messages: Membrane

93934:CPB2
gene id: 93934:CPB2
uniprot id: A0A8C2UAX6
names: Similarity
messages: Belongs to the peptidase M14 family.

93934:KBTBD8
gene id: 93934:KBTBD8
uniprot id: A0A8C2U8L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KBTBD8 family.
messages: Golgi apparatus
messages: spindle

93934:DLX5
gene id: 93934:DLX5
uniprot id: A0A8C2TKM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

93934:RNF182
gene id: 93934:RNF182
uniprot id: A0A8C2U0L0
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with ATP6V0C.
messages: Membrane

93934:LOC107323764
gene id: 93934:LOC107323764
uniprot id: A0A8C2TYY0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:GALNT12
gene id: 93934:GALNT12
uniprot id: A0A8C2YDD4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:GJC1
gene id: 93934:GJC1
uniprot id: A0A8C2U620
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family. Gamma-type subfamily.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:VEGFA
gene id: 93934:VEGFA
uniprot id: P67965
names: Developmental Stage
names: Domain
names: Function
names: Similarity
names: Subunit
names: Tissue Specificity
messages: Belongs to the PDGF/VEGF growth factor family.
messages: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin (By similarity).
messages: Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity).
messages: Isoform VEGF-166 is expressed early at day 1 and increases during gastrulation. Expression of isoform VEGF-190 is detectable only from day 2.
messages: Isoform VEGF-190 contains a basic insert which acts as a cell retention signal.
messages: Widely expressed. Abundantly and equally expressed in heart and liver. In kidney glomeruli, brain and yolk sac, isoform VEGF-166 is 5- to 10-times more abundant than isoform VEGF-190.

93934:SLC1A2
gene id: 93934:SLC1A2
uniprot id: A0A8C2TWM4
uniprot id: A0A8C2YDR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

93934:RAB21
gene id: 93934:RAB21
uniprot id: A0A8C2U1U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cleavage furrow
messages: Cytoplasmic vesicle membrane
messages: Early endosome membrane
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: neuron projection
messages: trans-Golgi network

93934:HOXB13
gene id: 93934:HOXB13
uniprot id: A0A8C2UB53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

93934:PRLR
gene id: 93934:PRLR
uniprot id: A0A0K2S3B3
uniprot id: A0A8C2T1Z6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: Membrane
messages: The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
messages: The box 1 motif is required for JAK interaction and/or activation.
messages: This is a receptor for the anterior pituitary hormone prolactin.

93934:UBE2G1
gene id: 93934:UBE2G1
uniprot id: A0A8C2T958
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:STRA6
gene id: 93934:STRA6
uniprot id: A0A8C2Y8R8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:NPVF
gene id: 93934:NPVF
uniprot id: A0A0F7CWL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FARP (FMRFamide related peptide) family.
messages: Secreted

93934:DSCC1
gene id: 93934:DSCC1
uniprot id: A0A8C2SYK7
names: Similarity
messages: Belongs to the DCC1 family.

93934:CSRNP1
gene id: 93934:CSRNP1
uniprot id: A0A8C2THB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

93934:PNPLA4
gene id: 93934:PNPLA4
uniprot id: A0A8C2U684
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107319304
gene id: 93934:LOC107319304
uniprot id: A0A8C2YD17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

93934:INTS12
gene id: 93934:INTS12
uniprot id: A0A8C2TB97
uniprot id: A0A8C2Y9W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 12 family.
messages: Nucleus

93934:ENPP6
gene id: 93934:ENPP6
uniprot id: A0A8C2TEX4
names: Similarity
messages: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

93934:BEST1
gene id: 93934:BEST1
uniprot id: A0A8C2U5R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Membrane

93934:NINJ2
gene id: 93934:NINJ2
uniprot id: A0A8C2UBN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ninjurin family.
messages: Membrane

93934:LRRC42
gene id: 93934:LRRC42
uniprot id: A0A8C2TPG0
names: Similarity
messages: Belongs to the LRRC42 family.

93934:MOSPD1
gene id: 93934:MOSPD1
uniprot id: A0A8C2TXP7
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

93934:ESRRG
gene id: 93934:ESRRG
uniprot id: A0A8C2T3Y5
uniprot id: A0A8C2T6G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

93934:C6H10orf90
gene id: 93934:C6H10orf90
uniprot id: A0A8C2Y5D5
names: Subcellular Location Annotation
messages: centrosome

93934:THRB
gene id: 93934:THRB
uniprot id: A0A8C2TK68
uniprot id: A0A8C2TP80
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

93934:LMNB2
gene id: 93934:LMNB2
uniprot id: A0A8C2T5A5
names: Similarity
messages: Belongs to the intermediate filament family.

93934:CHRM2
gene id: 93934:CHRM2
uniprot id: A0A8C2UG89
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins.

93934:ABI1
gene id: 93934:ABI1
uniprot id: A0A8C2Y6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABI family.
messages: cytoskeleton
messages: filopodium
messages: lamellipodium

93934:TBL3
gene id: 93934:TBL3
uniprot id: A0A8C2T0V8
names: Subcellular Location Annotation
messages: nucleolus

93934:GHR
gene id: 93934:GHR
uniprot id: A0A8C2TIA4
names: Function
names: Similarity
messages: Belongs to the type I cytokine receptor family. Type 1 subfamily.
messages: The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.

93934:HESX1
gene id: 93934:HESX1
uniprot id: A0A8C2TMS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANF homeobox family.
messages: Nucleus

93934:CEP63
gene id: 93934:CEP63
uniprot id: A0A8C2U720
names: Similarity
messages: Belongs to the CEP63 family.

93934:EOGT
gene id: 93934:EOGT
uniprot id: A0A8C2U3H1
uniprot id: A0A8C2YFH9
names: Similarity
messages: Belongs to the glycosyltransferase 61 family.

93934:BRS3
gene id: 93934:BRS3
uniprot id: A0A8C2U069
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with C6orf89.
messages: Membrane

93934:SGTA
gene id: 93934:SGTA
uniprot id: A0A8C2TF90
names: Similarity
messages: Belongs to the SGT family.

93934:SMC1B
gene id: 93934:SMC1B
uniprot id: A0A8C2U1E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Chromosome
messages: Nucleus

93934:AGTR1
gene id: 93934:AGTR1
uniprot id: A0A8C2TKH0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for angiotensin II, a vasoconstricting peptide, which acts as a key regulator of blood pressure and sodium retention by the kidney. The activated receptor in turn couples to G-alpha proteins G(q) and thus activates phospholipase C and increases the cytosolic Ca(2+) concentrations, which in turn triggers cellular responses such as stimulation of protein kinase C.

93934:CTBP2
gene id: 93934:CTBP2
uniprot id: A0A8C2Y517
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
messages: Nucleus

93934:SESN1
gene id: 93934:SESN1
uniprot id: A0A8C2TFX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

93934:CER1
gene id: 93934:CER1
uniprot id: A0A8C2Y8M8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:GALNT15
gene id: 93934:GALNT15
uniprot id: A0A8C2TKB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:MRPL50
gene id: 93934:MRPL50
uniprot id: A0A8C2SQK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

93934:PAX6
gene id: 93934:PAX6
uniprot id: P47238
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: May be a transcription factor with important functions in eye and nasal development.
messages: Nucleus

93934:XPR1
gene id: 93934:XPR1
uniprot id: A0A8C2UEF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

93934:PRICKLE2
gene id: 93934:PRICKLE2
uniprot id: A0A8C2U6Y3
uniprot id: A0A8C2YFG7
names: Similarity
messages: Belongs to the prickle / espinas / testin family.

93934:ADORA2B
gene id: 93934:ADORA2B
uniprot id: A0A8C2TRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

93934:SV2A
gene id: 93934:SV2A
uniprot id: A0A8C2YCR8
names: Subcellular Location Annotation
messages: synaptic vesicle membrane

93934:C7
gene id: 93934:C7
uniprot id: A0A8C2TFH0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:TIMP3
gene id: 93934:TIMP3
uniprot id: A0A8C2YFJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I35 (TIMP) family.
messages: extracellular matrix

93934:PRKCB
gene id: 93934:PRKCB
uniprot id: A0A8C2TD21
uniprot id: A0A8C2TI85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm
messages: Membrane
messages: Nucleus

93934:AGPAT5
gene id: 93934:AGPAT5
uniprot id: A0A8C2T5Y0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:CDC37L1
gene id: 93934:CDC37L1
uniprot id: A0A8C2SS06
uniprot id: A0A8C2SU40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

93934:LOC107309092
gene id: 93934:LOC107309092
uniprot id: A0A8C2YA89
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:CNOT1
gene id: 93934:CNOT1
uniprot id: A0A8C2YB22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT1 family.
messages: Nucleus

93934:PLK2
gene id: 93934:PLK2
uniprot id: A0A8C2SST7
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

93934:SLC25A1
gene id: 93934:SLC25A1
uniprot id: A0A8C2UAQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:KIFBP
gene id: 93934:KIFBP
uniprot id: A0A8C2SSL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KIF-binding protein family.
messages: cytoskeleton

93934:TES
gene id: 93934:TES
uniprot id: A0A8C2TJL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prickle / espinas / testin family.
messages: focal adhesion

93934:LOC107307805
gene id: 93934:LOC107307805
uniprot id: A0A8C2U8R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMP-30/CGR1 family.
messages: Cytoplasm

93934:LOC107320984
gene id: 93934:LOC107320984
uniprot id: A0A8C2YEF9
names: Similarity
messages: Belongs to the DNase I family.

93934:MSRB3
gene id: 93934:MSRB3
uniprot id: A0A8C2TXR5
uniprot id: A0A8C2U0M5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.
messages: Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residues.

93934:KIF20A
gene id: 93934:KIF20A
uniprot id: A0A8C2T9G5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:MED6
gene id: 93934:MED6
uniprot id: A0A8C2TWB0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:MAP3K5
gene id: 93934:MAP3K5
uniprot id: A0A8C2TCH8
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

93934:SEMA4B
gene id: 93934:SEMA4B
uniprot id: A0A8C2UH90
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:NSA2
gene id: 93934:NSA2
uniprot id: A0A8C2SS36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

93934:NOVA1
gene id: 93934:NOVA1
uniprot id: A0A8C2U3M7
uniprot id: A0A8C2YF60
names: Subcellular Location Annotation
messages: Cytoplasm

93934:ZCCHC17
gene id: 93934:ZCCHC17
uniprot id: A0A8C2TWX0
names: Subcellular Location Annotation
messages: nucleolus

93934:SPARC
gene id: 93934:SPARC
uniprot id: O93390
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity).
messages: Belongs to the SPARC family.
messages: basement membrane

93934:LOC107325236
gene id: 93934:LOC107325236
uniprot id: A0A8C2Y716
names: Similarity
messages: Belongs to the intermediate filament family.

93934:PELO
gene id: 93934:PELO
uniprot id: A0A8C2YAT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.
messages: Nucleus

93934:ZFP36L2
gene id: 93934:ZFP36L2
uniprot id: A0A8C2TA91
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the cytoplasmic CCR4-NOT deadenylase complex to trigger ARE-containing mRNA deadenylation and decay processes.
messages: Cytoplasm
messages: Nucleus
messages: Zinc-finger RNA-binding protein that destabilizes several cytoplasmic AU-rich element (ARE)-containing mRNA transcripts by promoting their poly(A) tail removal or deadenylation, and hence provide a mechanism for attenuating protein synthesis. Acts as a 3'-untranslated region (UTR) ARE mRNA-binding adapter protein to communicate signaling events to the mRNA decay machinery. Functions by recruiting the CCR4-NOT deadenylase complex and probably other components of the cytoplasmic RNA decay machinery to the bound ARE-containing mRNAs, and hence promotes ARE-mediated mRNA deadenylation and decay processes. Binds to 3'-UTR ARE of numerous mRNAs.

93934:SLITRK6
gene id: 93934:SLITRK6
uniprot id: A0A8C2U7W8
names: Similarity
messages: Belongs to the SLITRK family.

93934:IRX1
gene id: 93934:IRX1
uniprot id: A0A8C2TVW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

93934:ING4
gene id: 93934:ING4
uniprot id: A0A8C2U299
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

93934:ABCG4
gene id: 93934:ABCG4
uniprot id: A0A8C2TBV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

93934:SLC6A20
gene id: 93934:SLC6A20
uniprot id: A0A8C2SWL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

93934:SGK2
gene id: 93934:SGK2
uniprot id: A0A8C2UCR6
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PTPN3
gene id: 93934:PTPN3
uniprot id: A0A8C2TX01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

93934:PCMTD1
gene id: 93934:PCMTD1
uniprot id: A0A8C2TGD2
names: Similarity
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.

93934:TIMM13
gene id: 93934:TIMM13
uniprot id: A0A8C2T1H8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

93934:NEO1
gene id: 93934:NEO1
uniprot id: A0A8C2T4F5
uniprot id: A0A8C2T7F0
uniprot id: A0A8C2T9Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. DCC family.
messages: Membrane

93934:ATP1B1
gene id: 93934:ATP1B1
uniprot id: A0A8C2YF31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the X(+)/potassium ATPases subunit beta family.
messages: Cell membrane
messages: Membrane
messages: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.

93934:LOC107325190
gene id: 93934:LOC107325190
uniprot id: A0A8C2SYT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

93934:EEF1B2
gene id: 93934:EEF1B2
uniprot id: A0A8C2TWA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the EF-1-beta/EF-1-delta family.
messages: EF-1 is composed of 4 subunits: alpha, beta, delta, and gamma.
messages: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

93934:UIMC1
gene id: 93934:UIMC1
uniprot id: A0A8C2TI31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAP80 family.
messages: Nucleus

93934:DYNLT1
gene id: 93934:DYNLT1
uniprot id: A0A8C2T808
names: Similarity
messages: Belongs to the dynein light chain Tctex-type family.

93934:MAP3K21
gene id: 93934:MAP3K21
uniprot id: A0A8C2SSY5
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

93934:MPPED2
gene id: 93934:MPPED2
uniprot id: A0A8C2TWL3
names: Similarity
messages: Belongs to the UPF0046 family.

93934:PRR5L
gene id: 93934:PRR5L
uniprot id: A0A8C2TF40
names: Similarity
messages: Belongs to the PROTOR family.

93934:NIT1
gene id: 93934:NIT1
uniprot id: A0A8C2SM33
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.

93934:NPBWR1
gene id: 93934:NPBWR1
uniprot id: A0A8C2TG23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LOC107325127
gene id: 93934:LOC107325127
uniprot id: A0A8C2SYR2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93934:IMPA1
gene id: 93934:IMPA1
uniprot id: A0A8C2TKJ1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93934:SF3B3
gene id: 93934:SF3B3
uniprot id: A0A8C2T6I9
names: Subcellular Location Annotation
messages: Nucleus

93934:OTUD7B
gene id: 93934:OTUD7B
uniprot id: A0A8C2TU04
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:ADAMTS6
gene id: 93934:ADAMTS6
uniprot id: A0A8C2TIJ8
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:VILL
gene id: 93934:VILL
uniprot id: A0A8C2TI23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: filopodium tip
messages: lamellipodium
messages: microvillus
messages: ruffle

93934:LOC107310210
gene id: 93934:LOC107310210
uniprot id: A0A8C2TFI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

93934:POU6F2
gene id: 93934:POU6F2
uniprot id: A0A8C2T0W9
uniprot id: A0A8C2T301
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

93934:RFLNA
gene id: 93934:RFLNA
uniprot id: A0A8C2UCN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Refilin family.
messages: Interacts with FLNA and FLNB.
messages: cytoskeleton

93934:SEMA6C
gene id: 93934:SEMA6C
uniprot id: A0A8C2TTQ9
uniprot id: A0A8C2TZ46
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:FAXC
gene id: 93934:FAXC
uniprot id: A0A8C2SMM7
names: Similarity
messages: Belongs to the FAX family.

93934:YARS2
gene id: 93934:YARS2
uniprot id: A0A8C2UB26
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:FICD
gene id: 93934:FICD
uniprot id: A0A8C2T6X4
names: Similarity
messages: Belongs to the fic family.

93934:CCDC93
gene id: 93934:CCDC93
uniprot id: A0A8C2UHS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC93 family.
messages: Early endosome

93934:OPA1
gene id: 93934:OPA1
uniprot id: A0A8C2TQP2
uniprot id: A0A8C2TTB8
uniprot id: A0A8C2YCJ1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion membrane

93934:LOC107306279
gene id: 93934:LOC107306279
uniprot id: A0A8C2Y9Z4
names: Similarity
messages: Belongs to the FBPase class 1 family.

93934:NAF1
gene id: 93934:NAF1
uniprot id: A0A8C2SLN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

93934:GORASP1
gene id: 93934:GORASP1
uniprot id: A0A8C2TKC2
names: Similarity
messages: Belongs to the GORASP family.

93934:GLI3
gene id: 93934:GLI3
uniprot id: A0A8C2Y7Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Cytoplasm
messages: Nucleus

93934:MFAP5
gene id: 93934:MFAP5
uniprot id: A0A8C2U3Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MFAP family.
messages: extracellular matrix

93934:CFAP300
gene id: 93934:CFAP300
uniprot id: A0A8C2Y6J0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP300 family.
messages: Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. May play a role in outer and inner dynein arm assembly.
messages: Cytoplasm

93934:CDKN1C
gene id: 93934:CDKN1C
uniprot id: A0A8C2U4N7
names: Similarity
messages: Belongs to the CDI family.

93934:RARS2
gene id: 93934:RARS2
uniprot id: A0A8C2SWW9
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:AMN
gene id: 93934:AMN
uniprot id: A0A8C2ST88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:ORMDL1
gene id: 93934:ORMDL1
uniprot id: A0A8C2TP94
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORM family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Negative regulator of sphingolipid synthesis.

93934:TRAK1
gene id: 93934:TRAK1
uniprot id: A0A8C2SVP7
uniprot id: A0A8C2SYR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the milton family.
messages: Early endosome
messages: Mitochondrion

93934:B3GNT2
gene id: 93934:B3GNT2
uniprot id: A0A8C2SQ03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:CKMT2
gene id: 93934:CKMT2
uniprot id: A0A8C2SNT1
names: Similarity
messages: Belongs to the ATP:guanido phosphotransferase family.

93934:MTMR1
gene id: 93934:MTMR1
uniprot id: A0A8C2SMN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

93934:RAB11FIP3
gene id: 93934:RAB11FIP3
uniprot id: A0A8C2YER0
uniprot id: A0A8C2YER8
names: Subcellular Location Annotation
messages: Cleavage furrow
messages: Endosome membrane
messages: Membrane
messages: Midbody
messages: Recycling endosome membrane

93934:AMPD2
gene id: 93934:AMPD2
uniprot id: A0A8C2T9R0
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

93934:ADGRA3
gene id: 93934:ADGRA3
uniprot id: A0A8C2U6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

93934:RFX2
gene id: 93934:RFX2
uniprot id: A0A8C2TFQ0
names: Subcellular Location Annotation
messages: Nucleus

93934:IL10RB
gene id: 93934:IL10RB
uniprot id: A0A8C2SZA2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tissue factor family.
messages: Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade.
messages: Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII.

93934:PIK3CA
gene id: 93934:PIK3CA
uniprot id: A0A8C2TT96
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

93934:AKT3
gene id: 93934:AKT3
uniprot id: A0A8C2TQB7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

93934:SLC18B1
gene id: 93934:SLC18B1
uniprot id: A0A8C2TCK2
names: Subcellular Location Annotation
messages: Membrane

93934:JAKMIP2
gene id: 93934:JAKMIP2
uniprot id: A0A8C2UCK1
names: Similarity
messages: Belongs to the JAKMIP family.

93934:UROS
gene id: 93934:UROS
uniprot id: A0A8C2SMS5
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

93934:SNX2
gene id: 93934:SNX2
uniprot id: A0A8C2Y7W6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane
messages: lamellipodium

93934:ITGB3
gene id: 93934:ITGB3
uniprot id: A0A8C2YG86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin beta chain family.
messages: Membrane

93934:NDUFAB1
gene id: 93934:NDUFAB1
uniprot id: A0A8C2TF07
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

93934:LOC107315958
gene id: 93934:LOC107315958
uniprot id: A0A8C2YGG1
names: Subcellular Location Annotation
messages: Nucleus

93934:YY1
gene id: 93934:YY1
uniprot id: A0A8C2STE5
names: Similarity
messages: Belongs to the YY transcription factor family.

93934:COPS4
gene id: 93934:COPS4
uniprot id: A0A8C2TF42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSN4 family.
messages: Nucleus
messages: Vesicle
messages: synaptic vesicle

93934:CASTOR2
gene id: 93934:CASTOR2
uniprot id: A0A8C2SXS5
names: Similarity
messages: Belongs to the GATS family.

93934:NGB
gene id: 93934:NGB
uniprot id: A0A8C2U7F4
names: Similarity
messages: Belongs to the globin family.

93934:CAP2
gene id: 93934:CAP2
uniprot id: A0A8C2U0C7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAP family.
messages: Cell membrane

93934:LOC107311283
gene id: 93934:LOC107311283
uniprot id: A0A8C2TS27
names: Similarity
messages: Belongs to the COX20 family.

93934:TMEM47
gene id: 93934:TMEM47
uniprot id: A0A8C2U3B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

93934:SLC4A4
gene id: 93934:SLC4A4
uniprot id: A0A8C2SNU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

93934:GORAB
gene id: 93934:GORAB
uniprot id: A0A8C2UIE1
names: Similarity
messages: Belongs to the GORAB family.

93934:HADHB
gene id: 93934:HADHB
uniprot id: A0A8C2TPB7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93934:KIF7
gene id: 93934:KIF7
uniprot id: A0A8C2UD76
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:SEMA6A
gene id: 93934:SEMA6A
uniprot id: A0A8C2SZR4
uniprot id: A0A8C2Y7R7
uniprot id: A0A8C2Y7R9
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:GRB2
gene id: 93934:GRB2
uniprot id: A0A8C2SP88
names: Subcellular Location Annotation
messages: Endosome
messages: Golgi apparatus
messages: Nucleus

93934:ESCO2
gene id: 93934:ESCO2
uniprot id: A0A8C2TRS4
names: Subcellular Location Annotation
messages: Nucleus

93934:DARS1
gene id: 93934:DARS1
uniprot id: A0A8C2YH78
names: Function
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.
messages: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA.

93934:PDIA6
gene id: 93934:PDIA6
uniprot id: A0A8C2TFM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen
messages: Melanosome

93934:TRMT11
gene id: 93934:TRMT11
uniprot id: A0A8C2T9J1
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

93934:LOC107306834
gene id: 93934:LOC107306834
uniprot id: A0A8C2TQ57
uniprot id: A0A8C2YC91
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

93934:ATRX
gene id: 93934:ATRX
uniprot id: A0A8C2U245
uniprot id: A0A8C2U3I7
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

93934:NOL12
gene id: 93934:NOL12
uniprot id: A0A8C2TP98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP17 family.
messages: nucleolus

93934:LOC107325765
gene id: 93934:LOC107325765
uniprot id: A0A8C2SW78
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

93934:DGKA
gene id: 93934:DGKA
uniprot id: A0A8C2SPC4
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

93934:PKDREJ
gene id: 93934:PKDREJ
uniprot id: A0A8C2TZ88
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polycystin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:FAM110A
gene id: 93934:FAM110A
uniprot id: A0A8C2T4N0
names: Similarity
messages: Belongs to the FAM110 family.

93934:GSKIP
gene id: 93934:GSKIP
uniprot id: A0A8C2Y5N1
names: Similarity
messages: Belongs to the GSKIP family.

93934:DHRS7C
gene id: 93934:DHRS7C
uniprot id: A0A8C2THY2
uniprot id: A0A8C2YB06
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:CACNA1D
gene id: 93934:CACNA1D
uniprot id: A0A8C2YC60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. CACNA1D subfamily.
messages: Membrane
messages: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death.

93934:LOC107309563
gene id: 93934:LOC107309563
uniprot id: A0A8C2TYA4
names: Similarity
messages: Belongs to the serpin family.

93934:MANEA
gene id: 93934:MANEA
uniprot id: A0A8C2SR83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:RPGRIP1L
gene id: 93934:RPGRIP1L
uniprot id: A0A8C2TNM5
names: Similarity
messages: Belongs to the RPGRIP1 family.

93934:SUZ12
gene id: 93934:SUZ12
uniprot id: A0A8C2UEB4
names: Similarity
messages: Belongs to the VEFS (VRN2-EMF2-FIS2-SU(Z)12) family.

93934:NOG
gene id: 93934:NOG
uniprot id: A0A8C2UJ66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the noggin family.
messages: Homodimer.
messages: Secreted

93934:TSC22D2
gene id: 93934:TSC22D2
uniprot id: A0A8C2U7I2
uniprot id: A0A8C2UAV5
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

93934:RIC3
gene id: 93934:RIC3
uniprot id: A0A8C2SWH6
names: Similarity
messages: Belongs to the ric-3 family.

93934:MSL3
gene id: 93934:MSL3
uniprot id: A0A8C2YFL6
names: Subcellular Location Annotation
messages: Nucleus

93934:POMK
gene id: 93934:POMK
uniprot id: A0A8C2T0E9
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Protein O-mannose kinase that specifically mediates phosphorylation at the 6-position of an O-mannose of the trisaccharide (N-acetylgalactosamine (GalNAc)-beta-1,3-N-acetylglucosamine (GlcNAc)-beta-1,4-mannose) to generate phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-1,3-N-acetylglucosamine-beta-1,4-(phosphate-6-)mannose). Phosphorylated O-mannosyl trisaccharide is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Only shows kinase activity when the GalNAc-beta-3-GlcNAc-beta-terminus is linked to the 4-position of O-mannose, suggesting that this disaccharide serves as the substrate recognition motif.

93934:INTS11
gene id: 93934:INTS11
uniprot id: A0A8C2TFV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS11 subfamily.
messages: Nucleus

93934:RPL39
gene id: 93934:RPL39
uniprot id: A0A8C2U625
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

93934:RNH1
gene id: 93934:RNH1
uniprot id: A0A8C2YFR2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Forms high-affinity heterodimers with RNASE1, ANG and RNASE2.
messages: Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.

93934:CCNK
gene id: 93934:CCNK
uniprot id: A0A8C2Y5N5
names: Similarity
messages: Belongs to the cyclin family.

93934:ADRM1
gene id: 93934:ADRM1
uniprot id: A0A8C2ST13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADRM1 family.
messages: Cytoplasm
messages: Nucleus

93934:SH3PXD2B
gene id: 93934:SH3PXD2B
uniprot id: A0A8C2T8K6
uniprot id: A0A8C2TAG7
uniprot id: A0A8C2TAW4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

93934:FAM163A
gene id: 93934:FAM163A
uniprot id: A0A8C2UJ10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

93934:CDC20
gene id: 93934:CDC20
uniprot id: A0A8C2TG47
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

93934:AMDHD1
gene id: 93934:AMDHD1
uniprot id: A0A8C2SZ55
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.

93934:TPPP3
gene id: 93934:TPPP3
uniprot id: A0A8C2TGF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPPP family.
messages: cytoskeleton

93934:NES
gene id: 93934:NES
uniprot id: A0A8C2YCV9
names: Similarity
messages: Belongs to the intermediate filament family.

93934:HDX
gene id: 93934:HDX
uniprot id: A0A8C2U353
names: Subcellular Location Annotation
messages: Nucleus

93934:ARMC10
gene id: 93934:ARMC10
uniprot id: A0A8C2T051
names: Similarity
messages: Belongs to the eutherian X-chromosome-specific Armcx family.

93934:FNIP2
gene id: 93934:FNIP2
uniprot id: A0A8C2SLH1
uniprot id: A0A8C2SNL0
uniprot id: A0A8C2SP79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNIP family.
messages: Lysosome membrane
messages: Membrane

93934:PREPL
gene id: 93934:PREPL
uniprot id: A0A8C2TD08
names: Similarity
messages: Belongs to the peptidase S9A family.

93934:AP1B1
gene id: 93934:AP1B1
uniprot id: A0A8C2YDT6
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

93934:SPON1
gene id: 93934:SPON1
uniprot id: A0A8C2TXG6
names: Subcellular Location Annotation
messages: extracellular matrix

93934:GRHPR
gene id: 93934:GRHPR
uniprot id: A0A8C2T2Y6
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

93934:PHF5A
gene id: 93934:PHF5A
uniprot id: A0A8C2Y9J8
names: Similarity
messages: Belongs to the PHF5 family.

93934:KIAA2013
gene id: 93934:KIAA2013
uniprot id: A0A8C2T4M9
names: Subcellular Location Annotation
messages: Membrane

93934:IDH1
gene id: 93934:IDH1
uniprot id: A0A8C2U0N9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

93934:TULP3
gene id: 93934:TULP3
uniprot id: A0A8C2U358
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUB family.
messages: Secreted

93934:BBS10
gene id: 93934:BBS10
uniprot id: A0A8C2TX28
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

93934:SCOC
gene id: 93934:SCOC
uniprot id: A0A8C2SRD6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCOC family.
messages: Positive regulator of amino acid starvation-induced autophagy.
messages: trans-Golgi network

93934:OGFRL1
gene id: 93934:OGFRL1
uniprot id: A0A8C2T548
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

93934:FOXI1
gene id: 93934:FOXI1
uniprot id: A0A8C2T3L3
names: Subcellular Location Annotation
messages: Nucleus

93934:FREM2
gene id: 93934:FREM2
uniprot id: A0A8C2YGQ1
names: Similarity
messages: Belongs to the FRAS1 family.

93934:IL15
gene id: 93934:IL15
uniprot id: A0A8C2SQ38
uniprot id: A0A8C2Y5J1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-15/IL-21 family.
messages: Secreted

93934:PAPSS2
gene id: 93934:PAPSS2
uniprot id: A0A8C2TQ62
names: Similarity
messages: In the C-terminal section; belongs to the sulfate adenylyltransferase family.
messages: In the N-terminal section; belongs to the APS kinase family.

93934:VPS4B
gene id: 93934:VPS4B
uniprot id: A0A8C2TYW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

93934:ITGAV
gene id: 93934:ITGAV
uniprot id: A0A8C2TUH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

93934:UPF2
gene id: 93934:UPF2
uniprot id: A0A8C2SV22
uniprot id: A0A8C2SWC6
names: Subcellular Location Annotation
messages: Cytoplasm

93934:TGFBI
gene id: 93934:TGFBI
uniprot id: A0A8C2SZM0
names: Subcellular Location Annotation
messages: extracellular matrix

93934:GABRA6
gene id: 93934:GABRA6
uniprot id: A0A8C2TAY0
uniprot id: A0A8C2TC76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:GABARAPL2
gene id: 93934:GABARAPL2
uniprot id: A0A8C2SVW2
names: Similarity
messages: Belongs to the ATG8 family.

93934:LAMB3
gene id: 93934:LAMB3
uniprot id: A0A8C2TYT6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:WLS
gene id: 93934:WLS
uniprot id: A0A8C2TS48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the wntless family.
messages: Golgi apparatus membrane
messages: Membrane

93934:SLC26A6
gene id: 93934:SLC26A6
uniprot id: A0A8C2TUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

93934:MRAP2
gene id: 93934:MRAP2
uniprot id: A0A8C2SV69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRAP family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ACAT2
gene id: 93934:ACAT2
uniprot id: A0A8C2SY87
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93934:LOC107312850
gene id: 93934:LOC107312850
uniprot id: A0A8C2TZ27
names: Subcellular Location Annotation
messages: Nucleus

93934:OTUD7A
gene id: 93934:OTUD7A
uniprot id: A0A8C2TKP6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:LOC107316096
gene id: 93934:LOC107316096
uniprot id: A0A8C2UC14
names: Function
names: Similarity
messages: Belongs to the GST superfamily. Omega family.
messages: Exhibits glutathione-dependent thiol transferase activity. Has high dehydroascorbate reductase activity and may contribute to the recycling of ascorbic acid. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA).

93934:TMEM50A
gene id: 93934:TMEM50A
uniprot id: A0A8C2U016
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

93934:ZDHHC15
gene id: 93934:ZDHHC15
uniprot id: A0A8C2U232
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:SEC31A
gene id: 93934:SEC31A
uniprot id: A0A8C2TCF0
uniprot id: A0A8C2TFG4
uniprot id: A0A8C2THQ3
uniprot id: A0A8C2YAB9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TMEM178B
gene id: 93934:TMEM178B
uniprot id: A0A8C2UE96
names: Similarity
messages: Belongs to the TMEM178 family.

93934:MRPL12
gene id: 93934:MRPL12
uniprot id: A0A8C2UFP7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

93934:GCLM
gene id: 93934:GCLM
uniprot id: A0A8C2Y964
names: Similarity
names: Subunit
messages: Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
messages: Heterodimer of a catalytic heavy chain and a regulatory light chain.

93934:LOC107322098
gene id: 93934:LOC107322098
uniprot id: A0A8C2UHH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

93934:ELOVL1
gene id: 93934:ELOVL1
uniprot id: A0A8C2TD44
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL1 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The C-terminal di-lysine motif may confer endoplasmic reticulum localization.

93934:TMEM263
gene id: 93934:TMEM263
uniprot id: A0A8C2YFM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM263 family.
messages: Membrane

93934:LOC107312474
gene id: 93934:LOC107312474
uniprot id: A0A8C2SQY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Endoplasmic reticulum membrane

93934:RUNX3
gene id: 93934:RUNX3
uniprot id: A0A8C2TZP3
names: Subcellular Location Annotation
messages: Nucleus

93934:TSEN15
gene id: 93934:TSEN15
uniprot id: A0A8C2UEU4
names: Similarity
messages: Belongs to the SEN15 family.

93934:ISCU
gene id: 93934:ISCU
uniprot id: A0A8C2T3W7
names: Function
names: Similarity
messages: Belongs to the NifU family.
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

93934:TTC36
gene id: 93934:TTC36
uniprot id: A0A8C2TH43
names: Similarity
messages: Belongs to the TTC36 family.

93934:RAP1GDS1
gene id: 93934:RAP1GDS1
uniprot id: A0A8C2Y8C9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum
messages: Mitochondrion
messages: cytosol

93934:RAB14
gene id: 93934:RAB14
uniprot id: A0A8C2TD45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Golgi apparatus membrane
messages: Recycling endosome
messages: phagosome
messages: trans-Golgi network membrane

93934:LOC107310095
gene id: 93934:LOC107310095
uniprot id: A0A8C2TFN0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:LARP7
gene id: 93934:LARP7
uniprot id: A0A8C2T280
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LARP7 family.
messages: nucleoplasm

93934:TRIM67
gene id: 93934:TRIM67
uniprot id: A0A8C2Y6L8
names: Subcellular Location Annotation
messages: cytoskeleton

93934:LIMK2
gene id: 93934:LIMK2
uniprot id: A0A8C2TMR5
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family.

93934:TP53INP1
gene id: 93934:TP53INP1
uniprot id: A0A8C2SLA8
names: Subcellular Location Annotation
messages: PML body
messages: autophagosome
messages: cytosol

93934:LOC107309790
gene id: 93934:LOC107309790
uniprot id: A0A8C2U2T3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

93934:SLC45A3
gene id: 93934:SLC45A3
uniprot id: A0A8C2TVW4
names: Subcellular Location Annotation
messages: Membrane

93934:TPRA1
gene id: 93934:TPRA1
uniprot id: A0A8C2TSK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0359 family.
messages: Membrane

93934:SPICE1
gene id: 93934:SPICE1
uniprot id: A0A8C2U2X3
names: Subcellular Location Annotation
messages: centriole
messages: spindle

93934:LOC107324457
gene id: 93934:LOC107324457
uniprot id: Q6PRV2
names: Similarity
messages: Belongs to the S-100 family.

93934:ILDR2
gene id: 93934:ILDR2
uniprot id: A0A8C2SSG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

93934:RETREG1
gene id: 93934:RETREG1
uniprot id: A0A8C2TVQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RETREG family.
messages: Membrane

93934:RCAN3
gene id: 93934:RCAN3
uniprot id: A0A8C2Y7D0
names: Similarity
messages: Belongs to the RCAN family.

93934:MFAP3
gene id: 93934:MFAP3
uniprot id: A0A8C2T5T4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:ZP4
gene id: 93934:ZP4
uniprot id: B5MGN5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPB subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Zona pellucida

93934:LOC107321056
gene id: 93934:LOC107321056
uniprot id: A0A8C2U8M0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Cleavage furrow
messages: Midbody
messages: cilium membrane
messages: spindle

93934:PHC1
gene id: 93934:PHC1
uniprot id: A0A8C2TYZ8
uniprot id: A0A8C2YEK3
names: Subcellular Location Annotation
messages: Nucleus

93934:NR1H3
gene id: 93934:NR1H3
uniprot id: A0A8C2TM94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nucleus

93934:SMC4
gene id: 93934:SMC4
uniprot id: A0A8C2U858
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Chromosome
messages: Nucleus

93934:BRPF3
gene id: 93934:BRPF3
uniprot id: A0A8C2SUN0
names: Subcellular Location Annotation
messages: Nucleus

93934:RTF2
gene id: 93934:RTF2
uniprot id: A0A8C2T784
names: Similarity
messages: Belongs to the rtf2 family.

93934:ST6GALNAC2
gene id: 93934:ST6GALNAC2
uniprot id: A0A8C2UBY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:SKAP2
gene id: 93934:SKAP2
uniprot id: A0A8C2YBX8
names: Similarity
messages: Belongs to the SKAP family.

93934:TCHP
gene id: 93934:TCHP
uniprot id: A0A8C2T746
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCHP family.
messages: cytoskeleton

93934:SKI
gene id: 93934:SKI
uniprot id: A0A8C2TAW3
uniprot id: A0A8C2TEI8
names: Similarity
messages: Belongs to the SKI family.

93934:NCSTN
gene id: 93934:NCSTN
uniprot id: A0A8C2TQ11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nicastrin family.
messages: Membrane

93934:PAIP2
gene id: 93934:PAIP2
uniprot id: A0A8C2YB17
names: Similarity
messages: Belongs to the PAIP2 family.

93934:DMC1
gene id: 93934:DMC1
uniprot id: A0A8C2TRW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. DMC1 subfamily.
messages: May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
messages: Nucleus

93934:GLUD1
gene id: 93934:GLUD1
uniprot id: A0A8C2TM78
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

93934:SLC13A3
gene id: 93934:SLC13A3
uniprot id: A0A8C2SMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

93934:RBPJL
gene id: 93934:RBPJL
uniprot id: A0A8C2UGL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

93934:PTK2
gene id: 93934:PTK2
uniprot id: A0A8C2TGT2
names: Subcellular Location Annotation
messages: Cell membrane
messages: focal adhesion

93934:LRP3
gene id: 93934:LRP3
uniprot id: A0A8C2TUV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:HOXD9
gene id: 93934:HOXD9
uniprot id: A0A8C2U1W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus
messages: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis.

93934:PTGER3
gene id: 93934:PTGER3
uniprot id: A0A8C2TU88
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:B3GAT1
gene id: 93934:B3GAT1
uniprot id: A0A8C2T3N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:C2H8orf37
gene id: 93934:C2H8orf37
uniprot id: A0A8C2SQJ6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be involved in photoreceptor outer segment disk morphogenesis.
messages: Photoreceptor inner segment

93934:FSHR
gene id: 93934:FSHR
uniprot id: A0A8C2SMX7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
messages: Cell membrane
messages: G protein-coupled receptor for follitropin, the follicle-stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
messages: Membrane

93934:LOC107317472
gene id: 93934:LOC107317472
uniprot id: A0A8C2Y4Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

93934:TSPAN14
gene id: 93934:TSPAN14
uniprot id: A0A8C2TN09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:DDX59
gene id: 93934:DDX59
uniprot id: A0A8C2UI35
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX59 subfamily.

93934:RBM17
gene id: 93934:RBM17
uniprot id: A0A8C2Y6I9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the spliceosome.
messages: Nucleus
messages: Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites.

93934:HSP90AA1
gene id: 93934:HSP90AA1
uniprot id: C7G492
names: Similarity
messages: Belongs to the heat shock protein 90 family.

93934:RIMKLB
gene id: 93934:RIMKLB
uniprot id: A0A8C2U244
names: Similarity
messages: Belongs to the RimK family.

93934:NDUFS3
gene id: 93934:NDUFS3
uniprot id: A0A8C2YAU3
names: Similarity
messages: Belongs to the complex I 30 kDa subunit family.

93934:CIRBP
gene id: 93934:CIRBP
uniprot id: A0A8C2TEH3
uniprot id: A0A8C2TER5
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

93934:NIPAL1
gene id: 93934:NIPAL1
uniprot id: A0A8C2YEH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

93934:CDH12
gene id: 93934:CDH12
uniprot id: A0A8C2TV52
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:UTP23
gene id: 93934:UTP23
uniprot id: A0A8C2SY50
names: Subcellular Location Annotation
messages: nucleolus

93934:LOC107310736
gene id: 93934:LOC107310736
uniprot id: A0A8C2YDU8
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

93934:GPR155
gene id: 93934:GPR155
uniprot id: A0A8C2U7F1
names: Subcellular Location Annotation
messages: Membrane

93934:B3GNT5
gene id: 93934:B3GNT5
uniprot id: A0A8C2TU46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:ZHX1
gene id: 93934:ZHX1
uniprot id: A0A8C2T193
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZHX family.
messages: Nucleus

93934:NKX2-5
gene id: 93934:NKX2-5
uniprot id: A0A8C2T911
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NK-2 homeobox family.
messages: Nucleus

93934:RAMP3
gene id: 93934:RAMP3
uniprot id: A0A8C2TSU8
names: Similarity
messages: Belongs to the RAMP family.

93934:NUDT7
gene id: 93934:NUDT7
uniprot id: A0A8C2TUX5
names: Similarity
messages: Belongs to the Nudix hydrolase family. PCD1 subfamily.

93934:TMEM63C
gene id: 93934:TMEM63C
uniprot id: A0A8C2UCI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

93934:SLC39A8
gene id: 93934:SLC39A8
uniprot id: A0A8C2T2T0
names: Subcellular Location Annotation
messages: Membrane

93934:CHRNB4
gene id: 93934:CHRNB4
uniprot id: A0A8C2T971
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:SUMO2
gene id: 93934:SUMO2
uniprot id: A0A8C2UEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

93934:MYCBP
gene id: 93934:MYCBP
uniprot id: A0A8C2TYQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AMY1 family.
messages: Nucleus

93934:USP1
gene id: 93934:USP1
uniprot id: A0A8C2YBZ2
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:SRD5A2
gene id: 93934:SRD5A2
uniprot id: A0A8C2TP76
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
messages: Membrane
messages: Microsome membrane

93934:AATF
gene id: 93934:AATF
uniprot id: A0A8C2U719
names: Similarity
messages: Belongs to the AATF family.

93934:STK11IP
gene id: 93934:STK11IP
uniprot id: A0A8C2YCL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STK11IP family.
messages: Cytoplasm

93934:FOXM1
gene id: 93934:FOXM1
uniprot id: A0A8C2YEJ2
names: Subcellular Location Annotation
messages: Nucleus

93934:TMED7
gene id: 93934:TMED7
uniprot id: A0A8C2SZY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: cis-Golgi network membrane

93934:ZDHHC21
gene id: 93934:ZDHHC21
uniprot id: A0A8C2T747
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:LOC107314802
gene id: 93934:LOC107314802
uniprot id: A0A8C2TIG1
names: Similarity
messages: Belongs to the TMEM178 family.

93934:C1H11orf87
gene id: 93934:C1H11orf87
uniprot id: A0A8C2SRV8
names: Subcellular Location Annotation
messages: Membrane

93934:NMNAT2
gene id: 93934:NMNAT2
uniprot id: A0A8C2UG83
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

93934:AGPAT3
gene id: 93934:AGPAT3
uniprot id: A0A8C2T8E0
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:LOC107319648
gene id: 93934:LOC107319648
uniprot id: A0A8C2TJT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-5A synthase family.
messages: Cytoplasm

93934:FGF13
gene id: 93934:FGF13
uniprot id: A0A8C2YEB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: dendrite
messages: filopodium
messages: growth cone
messages: sarcolemma

93934:ECRG4
gene id: 93934:ECRG4
uniprot id: A0A8C2TRJ0
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the augurin family.
messages: Cytoplasm
messages: Membrane
messages: Secreted

93934:CRHR1
gene id: 93934:CRHR1
uniprot id: A0A8C2U6G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

93934:LIPT1
gene id: 93934:LIPT1
uniprot id: A0A8C2SMI0
names: Similarity
messages: Belongs to the LplA family.

93934:LOC107316596
gene id: 93934:LOC107316596
uniprot id: A0A8C2TYQ1
names: Similarity
messages: Belongs to the peptidase S51 family.

93934:TMEM65
gene id: 93934:TMEM65
uniprot id: A0A8C2T0L2
uniprot id: A0A8C2T392
names: Subcellular Location Annotation
messages: Membrane

93934:GOLPH3
gene id: 93934:GOLPH3
uniprot id: A0A8C2Y857
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Golgi stack membrane
messages: Membrane
messages: trans-Golgi network membrane

93934:PSMA2
gene id: 93934:PSMA2
uniprot id: A0A8C2SMV2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

93934:SENP8
gene id: 93934:SENP8
uniprot id: A0A8C2T7G2
names: Similarity
messages: Belongs to the peptidase C48 family.

93934:MTFR1L
gene id: 93934:MTFR1L
uniprot id: A0A8C2YE92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

93934:DPM2
gene id: 93934:DPM2
uniprot id: A0A8C2UD00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

93934:ATXN1
gene id: 93934:ATXN1
uniprot id: A0A8C2YEX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

93934:SLC9A8
gene id: 93934:SLC9A8
uniprot id: A0A8C2T3T1
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

93934:MAP1LC3B
gene id: 93934:MAP1LC3B
uniprot id: A0A8C2YDC7
names: Similarity
messages: Belongs to the ATG8 family.

93934:TSPAN5
gene id: 93934:TSPAN5
uniprot id: A0A8C2T3G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:CELF2
gene id: 93934:CELF2
uniprot id: A0A8C2Y6K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CELF/BRUNOL family.
messages: Cytoplasm
messages: Nucleus

93934:RELL1
gene id: 93934:RELL1
uniprot id: A0A8C2U478
names: Similarity
messages: Belongs to the RELT family.

93934:HOXA13
gene id: 93934:HOXA13
uniprot id: A0A8C2YBT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

93934:TVP23A
gene id: 93934:TVP23A
uniprot id: A0A8C2U1E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Membrane

93934:LOC107324050
gene id: 93934:LOC107324050
uniprot id: A0A8C2T017
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:GPR61
gene id: 93934:GPR61
uniprot id: A0A8C2T9Z7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:RAB33B
gene id: 93934:RAB33B
uniprot id: A0A8C2SMN7
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

93934:LOC107325878
gene id: 93934:LOC107325878
uniprot id: A0A8C2SYA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. BTN/MOG family.
messages: Membrane

93934:PAH
gene id: 93934:PAH
uniprot id: A0A8C2UGE5
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

93934:CFI
gene id: 93934:CFI
uniprot id: A0A8C2T2W5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MSN
gene id: 93934:MSN
uniprot id: A0A8C2SR94
uniprot id: A0A8C2Y5T3
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

93934:FAM189A1
gene id: 93934:FAM189A1
uniprot id: A0A8C2TL74
names: Similarity
messages: Belongs to the ENTREP family.

93934:FAM149B1
gene id: 93934:FAM149B1
uniprot id: A0A8C2TNE9
uniprot id: A0A8C2TR12
names: Similarity
messages: Belongs to the FAM149 family.

93934:LOC107308634
gene id: 93934:LOC107308634
uniprot id: A0A8C2T3L8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:MRPL13
gene id: 93934:MRPL13
uniprot id: A0A8C2SYV8
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

93934:METRNL
gene id: 93934:METRNL
uniprot id: A0A8C2UFG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the meteorin family.
messages: Secreted

93934:HEXA
gene id: 93934:HEXA
uniprot id: A0A8C2T4A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

93934:LOC107310369
gene id: 93934:LOC107310369
uniprot id: A0A8C2SM07
names: Subcellular Location Annotation
messages: Membrane

93934:UCHL5
gene id: 93934:UCHL5
uniprot id: A0A8C2UIE6
names: Similarity
messages: Belongs to the peptidase C12 family.

93934:KCNJ11
gene id: 93934:KCNJ11
uniprot id: A0A8C2Y869
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ11 subfamily.
messages: Membrane

93934:TPX2
gene id: 93934:TPX2
uniprot id: A0A8C2SZN0
uniprot id: A0A8C2T1H9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPX2 family.
messages: Nucleus
messages: spindle pole

93934:NRP2
gene id: 93934:NRP2
uniprot id: A0A8C2YE12
names: Caution
names: Similarity
messages: Belongs to the neuropilin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CCDC126
gene id: 93934:CCDC126
uniprot id: A0A8C2TMU3
names: Subcellular Location Annotation
messages: Secreted

93934:GDAP2
gene id: 93934:GDAP2
uniprot id: A0A8C2U071
names: Similarity
messages: Belongs to the GDAP2 family.

93934:FUNDC1
gene id: 93934:FUNDC1
uniprot id: A0A8C2YBZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FUN14 family.
messages: Mitochondrion outer membrane

93934:HSPA14
gene id: 93934:HSPA14
uniprot id: A0A8C2Y735
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: cytosol

93934:CRPPA
gene id: 93934:CRPPA
uniprot id: A0A8C2TI65
uniprot id: A0A8C2TKR3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IspD/TarI cytidylyltransferase family. IspD subfamily.
messages: Homodimer.
messages: cytosol

93934:LOC107313102
gene id: 93934:LOC107313102
uniprot id: A0A8C2SQI2
names: Similarity
messages: Belongs to the MS4A family.

93934:ADGRG6
gene id: 93934:ADGRG6
uniprot id: A0A8C2TC94
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:PRIMPOL
gene id: 93934:PRIMPOL
uniprot id: A0A8C2TDI9
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

93934:LOC107312798
gene id: 93934:LOC107312798
uniprot id: A0A8C2U4A1
names: Similarity
messages: Belongs to the TENT family.

93934:MRPL24
gene id: 93934:MRPL24
uniprot id: A0A8C2TSP7
names: Similarity
messages: Belongs to the universal ribosomal protein uL24 family.

93934:FZD3
gene id: 93934:FZD3
uniprot id: A0A8C2TQQ5
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:UTS2
gene id: 93934:UTS2
uniprot id: A0A8C2T6I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the urotensin-2 family.
messages: Secreted

93934:BMP6
gene id: 93934:BMP6
uniprot id: A0A8C2YES9
names: Similarity
messages: Belongs to the TGF-beta family.

93934:HPGD
gene id: 93934:HPGD
uniprot id: A0A8C2TC20
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:COPA
gene id: 93934:COPA
uniprot id: A0A8C2TQB9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

93934:GPHB5
gene id: 93934:GPHB5
uniprot id: A0A8C2SZT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

93934:CENPU
gene id: 93934:CENPU
uniprot id: A0A8C2TB29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-U/AME1 family.
messages: Nucleus

93934:IRX5
gene id: 93934:IRX5
uniprot id: A0A8C2TMC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

93934:SLC24A4
gene id: 93934:SLC24A4
uniprot id: A0A8C2SNM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

93934:KCNJ6
gene id: 93934:KCNJ6
uniprot id: A0A8C2T5P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ6 subfamily.
messages: Membrane

93934:LOC107313875
gene id: 93934:LOC107313875
uniprot id: A0A8C2U6W6
names: Subcellular Location Annotation
messages: Nucleus

93934:UGGT2
gene id: 93934:UGGT2
uniprot id: A0A8C2UBA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

93934:FSHB
gene id: 93934:FSHB
uniprot id: Q8JIG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycoprotein hormones subunit beta family.
messages: Secreted

93934:RTN4IP1
gene id: 93934:RTN4IP1
uniprot id: A0A8C2TD69
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

93934:ATP6V0A4
gene id: 93934:ATP6V0A4
uniprot id: A0A8C2UEB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

93934:YWHAG
gene id: 93934:YWHAG
uniprot id: A0A8C2TC51
names: Similarity
messages: Belongs to the 14-3-3 family.

93934:COPS9
gene id: 93934:COPS9
uniprot id: A0A8C2SZW5
names: Similarity
messages: Belongs to the CSN9 family.

93934:PLLP
gene id: 93934:PLLP
uniprot id: A0A8C2TLV8
names: Subcellular Location Annotation
messages: Membrane

93934:C1R
gene id: 93934:C1R
uniprot id: A0A8C2YEL8
names: Caution
names: Function
names: Subunit
messages: C1 is a calcium-dependent trimolecular complex of C1q, C1r and C1s in the molar ration of 1:2:2. C1r is a dimer of identical chains, each of which is activated by cleavage into two chains, A and B, connected by disulfide bonds.
messages: C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CD38
gene id: 93934:CD38
uniprot id: A0A8C2U4F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADP-ribosyl cyclase family.
messages: Membrane

93934:L3MBTL3
gene id: 93934:L3MBTL3
uniprot id: A0A8C2T8U0
names: Subcellular Location Annotation
messages: Nucleus

93934:LAMTOR5
gene id: 93934:LAMTOR5
uniprot id: A0A8C2TF46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR5 family.
messages: Lysosome

93934:IDH3A
gene id: 93934:IDH3A
uniprot id: A0A8C2T8T6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Heterooligomer of subunits alpha (IDH3A), beta (IDH3B), and gamma (IDH3G) in the apparent ratio of 2:1:1. The heterodimer containing one IDH3A and one IDH3B subunit and the heterodimer containing one IDH3A and one IDH3G subunit assemble into a heterotetramer (which contains two subunits of IDH3A, one of IDH3B and one of IDH3G) and further into the heterooctamer.
messages: Mitochondrion

93934:LOC107306405
gene id: 93934:LOC107306405
uniprot id: A0A8C2TMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. Jun subfamily.
messages: Nucleus

93934:GALNT3
gene id: 93934:GALNT3
uniprot id: A0A8C2UF78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:NSUN5
gene id: 93934:NSUN5
uniprot id: A0A8C2SYF8
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

93934:SLC51A
gene id: 93934:SLC51A
uniprot id: A0A8C2YCI1
names: Subcellular Location Annotation
messages: Membrane

93934:EIF1
gene id: 93934:EIF1
uniprot id: A0A8C2SW46
names: Similarity
messages: Belongs to the SUI1 family.

93934:RFC2
gene id: 93934:RFC2
uniprot id: A0A8C2TE36
names: Similarity
messages: Belongs to the activator 1 small subunits family.

93934:ANAPC1
gene id: 93934:ANAPC1
uniprot id: A0A8C2TVL9
names: Similarity
messages: Belongs to the APC1 family.

93934:SARAF
gene id: 93934:SARAF
uniprot id: A0A8C2YAQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SARAF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LPAR3
gene id: 93934:LPAR3
uniprot id: A0A8C2T931
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:RIOX1
gene id: 93934:RIOX1
uniprot id: A0A8C2TVP6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROX family. NO66 subfamily.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase.
messages: nucleolus

93934:NLE1
gene id: 93934:NLE1
uniprot id: A0A8C2YEC8
names: Subcellular Location Annotation
messages: nucleolus

93934:CDK14
gene id: 93934:CDK14
uniprot id: A0A8C2T527
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:RPL9
gene id: 93934:RPL9
uniprot id: A0A8C2U7S8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

93934:PDCD4
gene id: 93934:PDCD4
uniprot id: A0A8C2U9G8
names: Similarity
messages: Belongs to the PDCD4 family.

93934:FGF1
gene id: 93934:FGF1
uniprot id: A0A8C2UEX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Cytoplasm
messages: Nucleus
messages: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and FGFR1 are essential for FGF1 signaling.
messages: Secreted
messages: cell cortex
messages: cytosol

93934:NFYB
gene id: 93934:NFYB
uniprot id: A0A8C2U5P2
uniprot id: A0A8C2U8W6
names: Function
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes. NF-Y can function as both an activator and a repressor, depending on its interacting cofactors.

93934:MCM10
gene id: 93934:MCM10
uniprot id: A0A8C2SW99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM10 family.
messages: Nucleus

93934:WASL
gene id: 93934:WASL
uniprot id: A0A8C2TJF6
names: Subcellular Location Annotation
messages: Nucleus

93934:FBXO25
gene id: 93934:FBXO25
uniprot id: A0A8C2T6N6
uniprot id: A0A8C2T938
names: Subcellular Location Annotation
messages: Nucleus

93934:DGKZ
gene id: 93934:DGKZ
uniprot id: A0A8C2TSB2
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

93934:ZNF277
gene id: 93934:ZNF277
uniprot id: A0A8C2TMY7
names: Similarity
messages: Belongs to the ZNF277 family.

93934:AZIN1
gene id: 93934:AZIN1
uniprot id: A0A8C2SRC9
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

93934:LOC107319431
gene id: 93934:LOC107319431
uniprot id: A0A8C2TWN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase IV family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

93934:CLN8
gene id: 93934:CLN8
uniprot id: A0A8C2TAC5
names: Subcellular Location Annotation
messages: Membrane

93934:NDUFB10
gene id: 93934:NDUFB10
uniprot id: A0A8C2Y7L6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit that is involved in the functional assembly of the mitochondrial respiratory chain complex I. Complex I has an NADH dehydrogenase activity with ubiquinone as an immediate electron acceptor and mediates the transfer of electrons from NADH to the respiratory chain.
messages: Belongs to the complex I NDUFB10 subunit family.
messages: Mitochondrion inner membrane

93934:WNT10A
gene id: 93934:WNT10A
uniprot id: A0A8C2TR14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:TMEM200B
gene id: 93934:TMEM200B
uniprot id: A0A8C2YEB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

93934:STK17A
gene id: 93934:STK17A
uniprot id: A0A8C2SN96
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:LOC107317233
gene id: 93934:LOC107317233
uniprot id: A0A8C2UHK2
names: Similarity
messages: Belongs to the janus family.

93934:SPRTN
gene id: 93934:SPRTN
uniprot id: A0A8C2SWM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Spartan family.
messages: Chromosome
messages: Nucleus

93934:FAM83G
gene id: 93934:FAM83G
uniprot id: A0A8C2Y6T8
names: Similarity
messages: Belongs to the FAM83 family.

93934:ABRAXAS1
gene id: 93934:ABRAXAS1
uniprot id: A0A8C2TD55
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM175 family. Abraxas subfamily.
messages: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
messages: Nucleus

93934:TAF12
gene id: 93934:TAF12
uniprot id: A0A8C2TXF9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

93934:INPP4B
gene id: 93934:INPP4B
uniprot id: A0A8C2SQ89
names: Similarity
messages: Belongs to the inositol 3,4-bisphosphate 4-phosphatase family.

93934:ANXA5
gene id: 93934:ANXA5
uniprot id: A0A8C2SWH8
names: Domain
names: Similarity
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.

93934:CSNK1A1
gene id: 93934:CSNK1A1
uniprot id: A0A8C2T8X4
uniprot id: A0A8C2T929
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PPIL1
gene id: 93934:PPIL1
uniprot id: A0A8C2TCF1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93934:GATA4
gene id: 93934:GATA4
uniprot id: A0A8C2SLY7
names: Subcellular Location Annotation
messages: Nucleus

93934:PITX3
gene id: 93934:PITX3
uniprot id: A0A8C2YFN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

93934:FEN1
gene id: 93934:FEN1
uniprot id: A0A8C2YC89
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

93934:DEGS1
gene id: 93934:DEGS1
uniprot id: A0A8C2T349
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Interacts with RLBP1; the interaction increases synthesis of chromophore-precursors by DEGS1.
messages: Membrane

93934:LOC107314121
gene id: 93934:LOC107314121
uniprot id: A0A8C2T5S5
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:FERMT1
gene id: 93934:FERMT1
uniprot id: A0A8C2STR7
names: Similarity
messages: Belongs to the kindlin family.

93934:AMH
gene id: 93934:AMH
uniprot id: A0A8C2TEA9
uniprot id: Q0P6K5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer; disulfide-linked.
messages: Secreted

93934:EED
gene id: 93934:EED
uniprot id: A0A8C2SVG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ESC family.
messages: Nucleus

93934:ATP6V0D2
gene id: 93934:ATP6V0D2
uniprot id: A0A8C2SLT0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

93934:ARHGEF3
gene id: 93934:ARHGEF3
uniprot id: A0A8C2TR93
names: Function
names: Subcellular Location Annotation
messages: Acts as guanine nucleotide exchange factor (GEF) for RhoA and RhoB GTPases.
messages: Cytoplasm

93934:DSP
gene id: 93934:DSP
uniprot id: A0A8C2YET8
names: Subcellular Location Annotation
messages: cytoskeleton

93934:SDC4
gene id: 93934:SDC4
uniprot id: A0A8C2UDR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

93934:S100A1
gene id: 93934:S100A1
uniprot id: A0A8C2TVF6
names: Similarity
messages: Belongs to the S-100 family.

93934:E2F6
gene id: 93934:E2F6
uniprot id: A0A8C2TFN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

93934:AGA
gene id: 93934:AGA
uniprot id: A0A8C2TCB3
uniprot id: A0A8C2TF01
names: Similarity
messages: Belongs to the Ntn-hydrolase family.

93934:LOC107325817
gene id: 93934:LOC107325817
uniprot id: A0A8C2SXJ3
names: Similarity
messages: Belongs to the intermediate filament family.

93934:LOC107320982
gene id: 93934:LOC107320982
uniprot id: A0A8C2U113
names: Similarity
messages: Belongs to the globin family.

93934:TSPAN3
gene id: 93934:TSPAN3
uniprot id: A0A8C2T6Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:FLOT2
gene id: 93934:FLOT2
uniprot id: A0A8C2TI41
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the band 7/mec-2 family. Flotillin subfamily.
messages: Endosome
messages: Heterooligomeric complex.
messages: Membrane

93934:CROT
gene id: 93934:CROT
uniprot id: A0A8C2T0G8
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

93934:MARCKS
gene id: 93934:MARCKS
uniprot id: A0A8C2TBM6
names: Similarity
messages: Belongs to the MARCKS family.

93934:GLRA3
gene id: 93934:GLRA3
uniprot id: A0A8C2TDZ9
uniprot id: A0A8C2YA42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synapse
messages: Synaptic cell membrane

93934:TNKS2
gene id: 93934:TNKS2
uniprot id: A0A8C2U6K9
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:NCAPH
gene id: 93934:NCAPH
uniprot id: A0A8C2TIE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

93934:ZDHHC22
gene id: 93934:ZDHHC22
uniprot id: A0A8C2UAX8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:BRINP2
gene id: 93934:BRINP2
uniprot id: A0A8C2UK19
names: Similarity
messages: Belongs to the BRINP family.

93934:LGI1
gene id: 93934:LGI1
uniprot id: A0A8C2U8F1
uniprot id: A0A8C2UAD7
names: Subcellular Location Annotation
messages: Secreted

93934:CHPF
gene id: 93934:CHPF
uniprot id: A0A8C2TNG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane

93934:PTPN6
gene id: 93934:PTPN6
uniprot id: A0A8C2U0C3
uniprot id: A0A8C2U2H6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

93934:LOC107318280
gene id: 93934:LOC107318280
uniprot id: A0A8C2TP08
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:NTNG2
gene id: 93934:NTNG2
uniprot id: A0A8C2T116
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CPSF6
gene id: 93934:CPSF6
uniprot id: A0A8C2TZL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Cytoplasm
messages: Nucleus speckle
messages: nucleoplasm

93934:MRPS17
gene id: 93934:MRPS17
uniprot id: A0A8C2TCD1
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

93934:SLC37A3
gene id: 93934:SLC37A3
uniprot id: A0A8C2UEA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93934:CCT2
gene id: 93934:CCT2
uniprot id: A0A8C2TW64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

93934:GANC
gene id: 93934:GANC
uniprot id: A0A8C2TUZ5
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

93934:ZP1
gene id: 93934:ZP1
uniprot id: Q910B7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ERRFI1
gene id: 93934:ERRFI1
uniprot id: A0A8C2T9B3
names: Subcellular Location Annotation
messages: Membrane
messages: Nucleus

93934:RPS28
gene id: 93934:RPS28
uniprot id: A0A8C2T0I2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

93934:ORC3
gene id: 93934:ORC3
uniprot id: A0A8C2SV46
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC3 family.
messages: Component of ORC, a complex composed of at least 6 subunits: ORC1, ORC2, ORC3, ORC4, ORC5 and ORC6. ORC is regulated in a cell-cycle dependent manner. It is sequentially assembled at the exit from anaphase of mitosis and disassembled as cells enter S phase.
messages: Nucleus

93934:LOC107322174
gene id: 93934:LOC107322174
uniprot id: A0A8C2UGE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.
messages: Membrane

93934:NDUFB9
gene id: 93934:NDUFB9
uniprot id: A0A8C2T1B0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I LYR family.
messages: Mammalian complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

93934:SART3
gene id: 93934:SART3
uniprot id: A0A8C2Y8H2
names: Subcellular Location Annotation
messages: nucleoplasm

93934:SMAD1
gene id: 93934:SMAD1
uniprot id: A0A8C2Y5D6
uniprot id: Q9I962
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: May form trimers with another Smad1 and the co-Smad Smad4.
messages: Nucleus
messages: Phosphorylated on serine by BMP type 1 receptor kinase.
messages: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).

93934:PAX2
gene id: 93934:PAX2
uniprot id: A0A8C2U7P6
names: Subcellular Location Annotation
messages: Nucleus

93934:HSP90B1
gene id: 93934:HSP90B1
uniprot id: C7G494
names: Similarity
messages: Belongs to the heat shock protein 90 family.

93934:LOC107324437
gene id: 93934:LOC107324437
uniprot id: A0A8C2TQD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
messages: Membrane

93934:BMP3
gene id: 93934:BMP3
uniprot id: A0A8C2THI6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

93934:INA
gene id: 93934:INA
uniprot id: A0A8C2U9Q8
names: Similarity
messages: Belongs to the intermediate filament family.

93934:SERPINF1
gene id: 93934:SERPINF1
uniprot id: A0A8C2TL97
names: Similarity
messages: Belongs to the serpin family.

93934:LOC107312293
gene id: 93934:LOC107312293
uniprot id: A0A8C2TIH1
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:CDPF1
gene id: 93934:CDPF1
uniprot id: A0A8C2YE71
names: Similarity
messages: Belongs to the CDPF1 family.

93934:BMT2
gene id: 93934:BMT2
uniprot id: A0A8C2TMV5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the BMT2 family.
messages: Interacts with the GATOR1 complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine. Interacts with the KICSTOR complex; interaction is disrupted when BMT2/SAMTOR binds S-adenosyl-L-methionine.
messages: S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling. Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase.

93934:NR2F1
gene id: 93934:NR2F1
uniprot id: A0A8C2SLK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:F9
gene id: 93934:F9
uniprot id: A0A8C2YED4
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca(2+) ions, phospholipids, and factor VIIIa.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:LAMP3
gene id: 93934:LAMP3
uniprot id: A0A8C2TR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMP family.
messages: Endosome membrane

93934:TATDN1
gene id: 93934:TATDN1
uniprot id: A0A8C2Y7M5
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

93934:RPL27
gene id: 93934:RPL27
uniprot id: A0A8C2Y7I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL27 family.
messages: Endoplasmic reticulum
messages: Rough endoplasmic reticulum

93934:PARD3
gene id: 93934:PARD3
uniprot id: A0A8C2SSK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR3 family.
messages: Cell junction
messages: Endomembrane system

93934:TMEM159
gene id: 93934:TMEM159
uniprot id: A0A8C2YG06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LDAF1 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Membrane

93934:SLC23A2
gene id: 93934:SLC23A2
uniprot id: A0A8C2TLT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93934:ONECUT1
gene id: 93934:ONECUT1
uniprot id: A0A8C2U1B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

93934:MAN1C1
gene id: 93934:MAN1C1
uniprot id: A0A8C2U0R9
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

93934:MAGI1
gene id: 93934:MAGI1
uniprot id: A0A8C2U6L6
uniprot id: A0A8C2U829
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107314285
gene id: 93934:LOC107314285
uniprot id: A0A8C2TPU2
names: Similarity
messages: Belongs to the CD225/Dispanin family.

93934:OLFML3
gene id: 93934:OLFML3
uniprot id: A0A8C2U333
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OLFML3 family.
messages: Secreted

93934:PRPF4
gene id: 93934:PRPF4
uniprot id: A0A8C2YE59
names: Subcellular Location Annotation
messages: Nucleus speckle

93934:DEGS2
gene id: 93934:DEGS2
uniprot id: A0A8C2SQU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:POU4F3
gene id: 93934:POU4F3
uniprot id: A0A8C2UF68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

93934:CLRN2
gene id: 93934:CLRN2
uniprot id: A0A8C2U5Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clarin family.
messages: Membrane

93934:RPL23
gene id: 93934:RPL23
uniprot id: A0A8C2SQ76
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

93934:ACYP1
gene id: 93934:ACYP1
uniprot id: A0A8C2U9M5
names: Similarity
messages: Belongs to the acylphosphatase family.

93934:LMOD2
gene id: 93934:LMOD2
uniprot id: A0A8C2TML6
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

93934:MEOX2
gene id: 93934:MEOX2
uniprot id: A0A8C2TLA0
names: Subcellular Location Annotation
messages: Nucleus

93934:PNN
gene id: 93934:PNN
uniprot id: A0A8C2YG66
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pinin family.
messages: Found in a mRNA splicing-dependent exon junction complex (EJC). Found in a complex with SR proteins. Found in a mRNP complex with RNPS1. Component of the PSAP complex consisting of RNPS1, SAP18 and PNN. Interacts with PNISR, CTBP1, CTBP2, KRT8, KRT18, KRT19, PS1D/PNO40, PPIG, RNPS1, SFRS4 and SRRM2. Identified in the spliceosome C complex.
messages: Nucleus speckle
messages: desmosome

93934:JMY
gene id: 93934:JMY
uniprot id: A0A8C2T6V6
names: Subcellular Location Annotation
messages: Membrane

93934:CDC42
gene id: 93934:CDC42
uniprot id: A0A8C2T7I5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Membrane
messages: Midbody
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

93934:ACOX3
gene id: 93934:ACOX3
uniprot id: A0A8C2U4K4
uniprot id: A0A8C2U6I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

93934:RIF1
gene id: 93934:RIF1
uniprot id: A0A8C2UCQ9
uniprot id: A0A8C2UHQ3
names: Subcellular Location Annotation
messages: Nucleus
messages: telomere

93934:EXOSC9
gene id: 93934:EXOSC9
uniprot id: A0A8C2ST84
names: Subcellular Location Annotation
messages: Cytoplasm

93934:DIP2C
gene id: 93934:DIP2C
uniprot id: A0A8C2SV06
uniprot id: A0A8C2SWE2
uniprot id: A0A8C2Y697
names: Similarity
messages: Belongs to the DIP2 family.

93934:AKAP5
gene id: 93934:AKAP5
uniprot id: A0A8C2SRQ6
names: Subcellular Location Annotation
messages: Membrane

93934:TMEM237
gene id: 93934:TMEM237
uniprot id: A0A8C2TUF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM237 family.
messages: Component of the transition zone in primary cilia. Required for ciliogenesis.
messages: Membrane
messages: cilium

93934:ST6GALNAC5
gene id: 93934:ST6GALNAC5
uniprot id: A0A8C2TBS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:ISM1
gene id: 93934:ISM1
uniprot id: A0A8C2SPI8
names: Similarity
messages: Belongs to the isthmin family.

93934:CFAP36
gene id: 93934:CFAP36
uniprot id: A0A8C2SLT7
names: Similarity
messages: Belongs to the CFAP36 family.

93934:TNFRSF6B
gene id: 93934:TNFRSF6B
uniprot id: A0A8C2T1G6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:METTL6
gene id: 93934:METTL6
uniprot id: A0A8C2TNW1
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METL family.
messages: S-adenosyl-L-methionine-dependent methyltransferase.

93934:FN3K
gene id: 93934:FN3K
uniprot id: A0A8C2YHA5
names: Similarity
messages: Belongs to the fructosamine kinase family.

93934:ATP6AP2
gene id: 93934:ATP6AP2
uniprot id: A0A8C2YEL2
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lysosome membrane
messages: Membrane
messages: autophagosome membrane
messages: clathrin-coated vesicle membrane
messages: dendritic spine membrane
messages: synaptic vesicle membrane

93934:RFTN2
gene id: 93934:RFTN2
uniprot id: A0A8C2YCZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the raftlin family.
messages: Cell membrane
messages: Membrane

93934:ELK3
gene id: 93934:ELK3
uniprot id: A0A8C2SZA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:PKP4
gene id: 93934:PKP4
uniprot id: A0A8C2UGZ0
names: Similarity
messages: Belongs to the beta-catenin family.

93934:NIBAN2
gene id: 93934:NIBAN2
uniprot id: A0A8C2YGQ2
names: Similarity
messages: Belongs to the Niban family.

93934:LOC107306711
gene id: 93934:LOC107306711
uniprot id: A0A8C2TMH4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Interacts with CHP1 and CHP2.
messages: Membrane

93934:LOC107318670
gene id: 93934:LOC107318670
uniprot id: A0A8C2T5K3
uniprot id: D0EX75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome P450 family.
messages: Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane

93934:CA7
gene id: 93934:CA7
uniprot id: A0A8C2TWF2
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93934:PRDM12
gene id: 93934:PRDM12
uniprot id: A0A8C2SSP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily.
messages: Involved in the positive regulation of histone H3-K9 dimethylation.
messages: Nucleus

93934:HSPA4L
gene id: 93934:HSPA4L
uniprot id: A0A8C2Y955
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93934:SPIRE2
gene id: 93934:SPIRE2
uniprot id: A0A8C2TUB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the spire family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: cytoskeleton

93934:TLCD3A
gene id: 93934:TLCD3A
uniprot id: A0A8C2U0L3
names: Subcellular Location Annotation
messages: Membrane

93934:UBE4B
gene id: 93934:UBE4B
uniprot id: A0A8C2TMS3
uniprot id: A0A8C2YBX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

93934:XYLT2
gene id: 93934:XYLT2
uniprot id: A0A8C2UHB3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 14 family. XylT subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: Monomer.

93934:CCNG2
gene id: 93934:CCNG2
uniprot id: A0A8C2Y9P1
names: Similarity
messages: Belongs to the cyclin family.

93934:IMMP1L
gene id: 93934:IMMP1L
uniprot id: A0A8C2TUM6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26 family.
messages: Heterodimer of 2 subunits, IMMPL1 and IMMPL2.
messages: Mitochondrion inner membrane

93934:LOC107308162
gene id: 93934:LOC107308162
uniprot id: A0A8C2UB84
names: Subcellular Location Annotation
messages: Chromosome

93934:PROKR1
gene id: 93934:PROKR1
uniprot id: A0A8C2TKJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:LOC107308193
gene id: 93934:LOC107308193
uniprot id: A0A8C2YGP7
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

93934:SLC25A12
gene id: 93934:SLC25A12
uniprot id: A0A8C2U2J7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

93934:IDUA
gene id: 93934:IDUA
uniprot id: A0A8C2TNV1
names: Similarity
messages: Belongs to the glycosyl hydrolase 39 family.

93934:MED30
gene id: 93934:MED30
uniprot id: A0A8C2T1A5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 30 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

93934:LOC107312645
gene id: 93934:LOC107312645
uniprot id: A0A8C2SVJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.
messages: Membrane

93934:CD44
gene id: 93934:CD44
uniprot id: A0A8C2TVD3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: microvillus

93934:RFC4
gene id: 93934:RFC4
uniprot id: A0A8C2TTD5
names: Similarity
messages: Belongs to the activator 1 small subunits family.

93934:CEP70
gene id: 93934:CEP70
uniprot id: A0A8C2UFJ6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Directly interacts with tubulin-gamma; this interaction determines centrosomal localization.
messages: Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
messages: centrosome

93934:ST7
gene id: 93934:ST7
uniprot id: A0A8C2TJK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

93934:PIAS4
gene id: 93934:PIAS4
uniprot id: A0A8C2TFK2
names: Similarity
messages: Belongs to the PIAS family.

93934:LOC107325042
gene id: 93934:LOC107325042
uniprot id: A0A8C2U6F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

93934:PCSK5
gene id: 93934:PCSK5
uniprot id: A0A8C2T5N5
uniprot id: A0A8C2Y8U5
names: Similarity
messages: Belongs to the peptidase S8 family.

93934:CLPTM1L
gene id: 93934:CLPTM1L
uniprot id: A0A8C2TV90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLPTM1 family.
messages: Membrane

93934:LOC107312548
gene id: 93934:LOC107312548
uniprot id: A0A8C2Y977
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:CERS4
gene id: 93934:CERS4
uniprot id: A0A8C2T216
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

93934:NDUFA10
gene id: 93934:NDUFA10
uniprot id: A0A8C2TL13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFA10 subunit family.
messages: Complex I is composed of 45 different subunits. This a component of the hydrophobic protein fraction.
messages: Mitochondrion matrix

93934:SLC24A2
gene id: 93934:SLC24A2
uniprot id: A0A8C2T4Y6
uniprot id: A0A8C2T733
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

93934:FRG1
gene id: 93934:FRG1
uniprot id: A0A8C2T8I2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRG1 family.
messages: Cajal body
messages: nucleolus

93934:LOC107322045
gene id: 93934:LOC107322045
uniprot id: A0A8C2TZB7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:CPSF7
gene id: 93934:CPSF7
uniprot id: A0A8C2TN15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM CPSF6/7 family.
messages: Nucleus

93934:PIK3CB
gene id: 93934:PIK3CB
uniprot id: A0A8C2SZ42
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

93934:DTX4
gene id: 93934:DTX4
uniprot id: A0A8C2YFB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

93934:LOC107325235
gene id: 93934:LOC107325235
uniprot id: A0A8C2SZI8
names: Similarity
messages: Belongs to the intermediate filament family.

93934:PSMC6
gene id: 93934:PSMC6
uniprot id: A0A8C2YB69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

93934:ZNF687
gene id: 93934:ZNF687
uniprot id: A0A8C2TV17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

93934:KITLG
gene id: 93934:KITLG
uniprot id: A0A8C2T095
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCF family.
messages: Cytoplasm
messages: Homodimer, non-covalently linked.
messages: Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis.
messages: Secreted
messages: filopodium
messages: lamellipodium

93934:PLPP4
gene id: 93934:PLPP4
uniprot id: A0A8C2UCH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

93934:SDC2
gene id: 93934:SDC2
uniprot id: A0A8C2SLD3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

93934:LTV1
gene id: 93934:LTV1
uniprot id: A0A8C2Y9B2
names: Similarity
messages: Belongs to the LTV1 family.

93934:LOC107314117
gene id: 93934:LOC107314117
uniprot id: A0A8C2T5R6
names: Subcellular Location Annotation
messages: Nucleus

93934:MED17
gene id: 93934:MED17
uniprot id: A0A8C2SUC0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:ATXN1L
gene id: 93934:ATXN1L
uniprot id: A0A8C2SQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATXN1 family.
messages: Nucleus

93934:CCDC149
gene id: 93934:CCDC149
uniprot id: A0A8C2YFP9
names: Similarity
messages: Belongs to the CCDC149 family.

93934:DYNC1H1
gene id: 93934:DYNC1H1
uniprot id: A0A8C2SV14
names: Similarity
messages: Belongs to the dynein heavy chain family.

93934:PPM1D
gene id: 93934:PPM1D
uniprot id: A0A8C2U4T3
names: Similarity
messages: Belongs to the PP2C family.

93934:DENND5A
gene id: 93934:DENND5A
uniprot id: A0A8C2Y723
names: Caution
names: Similarity
messages: Belongs to the RAB6IP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PDLIM3
gene id: 93934:PDLIM3
uniprot id: A0A8C2T2Y3
uniprot id: A0A8C2T872
names: Subcellular Location Annotation
messages: Z line

93934:RPS19BP1
gene id: 93934:RPS19BP1
uniprot id: A0A8C2TRB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AROS family.
messages: nucleolus

93934:STEAP4
gene id: 93934:STEAP4
uniprot id: A0A8C2T3A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

93934:CYRIB
gene id: 93934:CYRIB
uniprot id: A0A8C2T3J6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

93934:RB1
gene id: 93934:RB1
uniprot id: A0A8C2YGM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

93934:LOC107313299
gene id: 93934:LOC107313299
uniprot id: A0A8C2TES4
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:ATP10A
gene id: 93934:ATP10A
uniprot id: A0A8C2UDX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:SDHD
gene id: 93934:SDHD
uniprot id: A0A8C2TQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CybS family.
messages: Component of complex II composed of four subunits: the flavoprotein (FP) SDHA, iron-sulfur protein (IP) SDHB, and a cytochrome b560 composed of SDHC and SDHD.
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

93934:LOC107316185
gene id: 93934:LOC107316185
uniprot id: A0A8C2UFN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

93934:EFEMP1
gene id: 93934:EFEMP1
uniprot id: A0A8C2U3I2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PGD
gene id: 93934:PGD
uniprot id: A0A8C2U3B1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

93934:CCDC124
gene id: 93934:CCDC124
uniprot id: A0A8C2TKU7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CCDC124 family.
messages: Interacts with RASGEF1B.
messages: Required for proper progression of late cytokinetic stages.

93934:LOC107312175
gene id: 93934:LOC107312175
uniprot id: A0A8C2T969
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93934:HTR2B
gene id: 93934:HTR2B
uniprot id: A0A8C2TP89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: synaptosome

93934:SRPX
gene id: 93934:SRPX
uniprot id: A0A8C2TZJ3
uniprot id: A0A8C2U1U3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107312450
gene id: 93934:LOC107312450
uniprot id: A0A8C2SS21
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:PRPF38B
gene id: 93934:PRPF38B
uniprot id: A0A8C2UE92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: May be required for pre-mRNA splicing.
messages: Nucleus

93934:SPPL2A
gene id: 93934:SPPL2A
uniprot id: A0A8C2UCB4
uniprot id: A0A8C2UE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A22B family.
messages: Membrane

93934:ACE2
gene id: 93934:ACE2
uniprot id: A0A8C2U8T6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the peptidase M2 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Membrane
messages: Secreted
messages: cilium

93934:ESS2
gene id: 93934:ESS2
uniprot id: A0A8C2T8D9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESS2 family.
messages: Nucleus

93934:TNFAIP1
gene id: 93934:TNFAIP1
uniprot id: A0A8C2YG57
names: Similarity
messages: Belongs to the BACURD family.

93934:SIDT1
gene id: 93934:SIDT1
uniprot id: A0A8C2U0L1
uniprot id: A0A8C2U405
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SID1 family.
messages: Membrane

93934:HLX
gene id: 93934:HLX
uniprot id: A0A8C2T5E5
names: Subcellular Location Annotation
messages: Nucleus

93934:LSM14A
gene id: 93934:LSM14A
uniprot id: A0A8C2YD76
names: Similarity
messages: Belongs to the LSM14 family.

93934:EYA1
gene id: 93934:EYA1
uniprot id: A0A8C2THV5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

93934:ALG8
gene id: 93934:ALG8
uniprot id: A0A8C2SZ77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:BTBD10
gene id: 93934:BTBD10
uniprot id: A0A8C2U8F5
uniprot id: A0A8C2UAD1
names: Subcellular Location Annotation
messages: Cytoplasm

93934:RAB38
gene id: 93934:RAB38
uniprot id: A0A8C2SUW6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

93934:SF3A2
gene id: 93934:SF3A2
uniprot id: A0A8C2TEJ4
names: Similarity
messages: Belongs to the SF3A2 family.

93934:MAN1B1
gene id: 93934:MAN1B1
uniprot id: A0A8C2TYX8
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

93934:LOC107324421
gene id: 93934:LOC107324421
uniprot id: A0A8C2TU37
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:WASHC3
gene id: 93934:WASHC3
uniprot id: A0A8C2YH35
names: Similarity
messages: Belongs to the CCDC53 family.

93934:ST8SIA5
gene id: 93934:ST8SIA5
uniprot id: A0A8C2SZJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:HUS1
gene id: 93934:HUS1
uniprot id: A0A8C2U7G6
names: Similarity
messages: Belongs to the HUS1 family.

93934:PDF
gene id: 93934:PDF
uniprot id: A0A8C2TTI4
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins.

93934:SEC22B
gene id: 93934:SEC22B
uniprot id: A0A8C2UIJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Melanosome
messages: Membrane
messages: SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

93934:SERINC3
gene id: 93934:SERINC3
uniprot id: A0A8C2SNK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

93934:KCNQ2
gene id: 93934:KCNQ2
uniprot id: A0A8C2ST73
uniprot id: A0A8C2Y669
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:PRDM4
gene id: 93934:PRDM4
uniprot id: A0A8C2U3T5
names: Function
names: Subcellular Location Annotation
messages: May function as a transcription factor involved in cell differentiation.
messages: Nucleus

93934:FGFR2
gene id: 93934:FGFR2
uniprot id: A0A8C2UAM5
uniprot id: A0A8C2UDS4
uniprot id: A0A8C2UFR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fibroblast growth factor receptor subfamily.
messages: Membrane

93934:TSG101
gene id: 93934:TSG101
uniprot id: A0A8C2THM8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

93934:UGP2
gene id: 93934:UGP2
uniprot id: A0A8C2TL35
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDPGP type 1 family.
messages: Homooctamer.
messages: UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.

93934:SNTA1
gene id: 93934:SNTA1
uniprot id: A0A8C2UHT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

93934:CXCR4
gene id: 93934:CXCR4
uniprot id: A0A8C2UDK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Late endosome
messages: Lysosome
messages: Membrane

93934:EDEM3
gene id: 93934:EDEM3
uniprot id: A0A8C2YHX0
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

93934:SLC24A1
gene id: 93934:SLC24A1
uniprot id: A0A8C2YHE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily.
messages: Membrane

93934:CD109
gene id: 93934:CD109
uniprot id: A0A8C2T398
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.

93934:LOC107322836
gene id: 93934:LOC107322836
uniprot id: A0A8C2UFA6
names: Similarity
messages: Belongs to the CBP3 family.

93934:BCO2
gene id: 93934:BCO2
uniprot id: A0A8C2TS30
uniprot id: A0A8C2TUQ6
names: Similarity
messages: Belongs to the carotenoid oxygenase family.

93934:EFNB2
gene id: 93934:EFNB2
uniprot id: A0A8C2TW37
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ephrin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:APIP
gene id: 93934:APIP
uniprot id: A0A8C2TX41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. Adducin subfamily.
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
messages: Cytoplasm

93934:NBN
gene id: 93934:NBN
uniprot id: A0A8C2SNK0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis.
messages: Component of the MRN complex.
messages: Nucleus
messages: telomere

93934:LOC107309564
gene id: 93934:LOC107309564
uniprot id: A0A8C2TY79
names: Similarity
messages: Belongs to the serpin family.

93934:FOXA1
gene id: 93934:FOXA1
uniprot id: A0A8C2U8K9
names: Subcellular Location Annotation
messages: Nucleus

93934:ATP8B1
gene id: 93934:ATP8B1
uniprot id: A0A8C2T111
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:L3MBTL2
gene id: 93934:L3MBTL2
uniprot id: A0A8C2TCT8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, BAT8 and YAF2.
messages: Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27'.

93934:REEP5
gene id: 93934:REEP5
uniprot id: A0A8C2YA32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

93934:PSMC3
gene id: 93934:PSMC3
uniprot id: A0A8C2TEY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

93934:DIPK1B
gene id: 93934:DIPK1B
uniprot id: A0A8C2TBT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

93934:ARVCF
gene id: 93934:ARVCF
uniprot id: A0A8C2U6T7
names: Similarity
messages: Belongs to the beta-catenin family.

93934:LOC107320080
gene id: 93934:LOC107320080
uniprot id: A0A8C2YHJ2
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

93934:BMP7
gene id: 93934:BMP7
uniprot id: A0A8C2T613
names: Similarity
messages: Belongs to the TGF-beta family.

93934:SOD3
gene id: 93934:SOD3
uniprot id: A0A8C2U9K2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

93934:STX2
gene id: 93934:STX2
uniprot id: A0A8C2U8U0
uniprot id: A0A8C2UDY1
names: Similarity
messages: Belongs to the syntaxin family.

93934:CNOT11
gene id: 93934:CNOT11
uniprot id: A0A8C2SQZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT11 family.
messages: Cytoplasm
messages: Nucleus

93934:KEF80 p08
gene id: 93934:KEF80_p08
uniprot id: A0A1D9CQS7
uniprot id: P50681
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase A chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel; it may play a direct role in the translocation of protons across the membrane.
messages: Mitochondrion inner membrane

93934:CDH2
gene id: 93934:CDH2
uniprot id: A0A8C2TFS5
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:MRRF
gene id: 93934:MRRF
uniprot id: A0A8C2TF02
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

93934:ST6GAL2
gene id: 93934:ST6GAL2
uniprot id: A0A8C2TMI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:HSPA2
gene id: 93934:HSPA2
uniprot id: A0ZT12
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93934:ZBED4
gene id: 93934:ZBED4
uniprot id: A0A8C2TA84
names: Subcellular Location Annotation
messages: Nucleus

93934:MOGAT2
gene id: 93934:MOGAT2
uniprot id: A0A8C2Y7H2
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107308775
gene id: 93934:LOC107308775
uniprot id: A0A8C2TI59
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium channel (TC 1.A.1.10) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
messages: Membrane

93934:HOPX
gene id: 93934:HOPX
uniprot id: A0A8C2TEN9
names: Subcellular Location Annotation
messages: Nucleus

93934:CDC45
gene id: 93934:CDC45
uniprot id: A0A8C2YG59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

93934:BRINP1
gene id: 93934:BRINP1
uniprot id: A0A8C2UEG2
names: Similarity
messages: Belongs to the BRINP family.

93934:GPN2
gene id: 93934:GPN2
uniprot id: A0A8C2TYP1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

93934:EVL
gene id: 93934:EVL
uniprot id: A0A8C2SS67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ena/VASP family.
messages: lamellipodium
messages: stress fiber

93934:SSH2
gene id: 93934:SSH2
uniprot id: A0A8C2YC48
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

93934:SLC35B4
gene id: 93934:SLC35B4
uniprot id: A0A8C2SXX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

93934:LOC107319997
gene id: 93934:LOC107319997
uniprot id: A0A8C2U6N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

93934:NCK2
gene id: 93934:NCK2
uniprot id: A0A8C2TN06
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum

93934:PTPN2
gene id: 93934:PTPN2
uniprot id: A0A8C2TAN1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

93934:TUSC3
gene id: 93934:TUSC3
uniprot id: A0A8C2TJ76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:EFHC1
gene id: 93934:EFHC1
uniprot id: A0A8C2SQ60
names: Subcellular Location Annotation
messages: cilium axoneme

93934:DCLRE1C
gene id: 93934:DCLRE1C
uniprot id: A0A8C2SWV6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA repair metallo-beta-lactamase (DRMBL) family.
messages: Nucleus

93934:HTR1E
gene id: 93934:HTR1E
uniprot id: A0A8C2Y6V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:IRF7
gene id: 93934:IRF7
uniprot id: A0A8C2YFR3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:C8G
gene id: 93934:C8G
uniprot id: A0A8C2TVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

93934:CDKN3
gene id: 93934:CDKN3
uniprot id: A0A8C2Y7U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family.
messages: May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues.
messages: perinuclear region

93934:SLC37A2
gene id: 93934:SLC37A2
uniprot id: A0A8C2SYH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93934:TALDO1
gene id: 93934:TALDO1
uniprot id: A0A8C2TRV8
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

93934:NKX6-3
gene id: 93934:NKX6-3
uniprot id: A0A8C2TW55
names: Subcellular Location Annotation
messages: Nucleus

93934:CHST11
gene id: 93934:CHST11
uniprot id: A0A8C2U9C3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:LOC107310132
gene id: 93934:LOC107310132
uniprot id: A0A8C2TC17
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

93934:TOR4A
gene id: 93934:TOR4A
uniprot id: A0A8C2U7R8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Membrane

93934:SGTB
gene id: 93934:SGTB
uniprot id: A0A8C2TEN8
names: Similarity
messages: Belongs to the SGT family.

93934:GADD45G
gene id: 93934:GADD45G
uniprot id: A0A8C2TDL4
names: Similarity
messages: Belongs to the GADD45 family.

93934:RPS24
gene id: 93934:RPS24
uniprot id: A0A8C2TF49
uniprot id: A0A8C2TGY8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

93934:TLL1
gene id: 93934:TLL1
uniprot id: A0A8C2SLL8
uniprot id: A0A8C2SMY5
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ENTPD4
gene id: 93934:ENTPD4
uniprot id: A0A8C2TTA3
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:HOXB6
gene id: 93934:HOXB6
uniprot id: A0A8C2U7N6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:EDNRA
gene id: 93934:EDNRA
uniprot id: A0A8C2SPJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with HDAC7 and KAT5.
messages: Membrane
messages: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

93934:TBL1XR1
gene id: 93934:TBL1XR1
uniprot id: A0A8C2TUA1
names: Similarity
messages: Belongs to the WD repeat EBI family.

93934:PAX9
gene id: 93934:PAX9
uniprot id: A0A8C2YG72
names: Subcellular Location Annotation
messages: Nucleus

93934:IL1RL1
gene id: 93934:IL1RL1
uniprot id: A0A8C2TMC1
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

93934:SGCA
gene id: 93934:SGCA
uniprot id: A0A8C2UBH6
names: Function
names: Similarity
messages: Belongs to the sarcoglycan alpha/epsilon family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.

93934:MAPK1
gene id: 93934:MAPK1
uniprot id: A0A8C2U8F6
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

93934:FAM76B
gene id: 93934:FAM76B
uniprot id: A0A8C2SXB9
names: Similarity
messages: Belongs to the FAM76 family.

93934:SGCZ
gene id: 93934:SGCZ
uniprot id: A0A8C2TEA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: cytoskeleton
messages: sarcolemma

93934:PSEN1
gene id: 93934:PSEN1
uniprot id: A0A8C2TST3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase A22A family.
messages: Cytoplasmic granule
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homodimer.
messages: Membrane
messages: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors.
messages: Synapse
messages: The PAL motif is required for normal active site conformation.
messages: axon
messages: neuron projection

93934:CSTF2
gene id: 93934:CSTF2
uniprot id: A0A8C2U2U1
names: Subcellular Location Annotation
messages: Nucleus

93934:ASAH1
gene id: 93934:ASAH1
uniprot id: A0A8C2T372
names: Similarity
messages: Belongs to the acid ceramidase family.

93934:NAPG
gene id: 93934:NAPG
uniprot id: A0A8C2TAJ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

93934:LOC107319112
gene id: 93934:LOC107319112
uniprot id: A4UYK2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PAX7
gene id: 93934:PAX7
uniprot id: A0A8C2U2G7
uniprot id: A0A8C2YFA1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

93934:RGS1
gene id: 93934:RGS1
uniprot id: A0A8C2UG57
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cytosol

93934:CASP6
gene id: 93934:CASP6
uniprot id: A0A8C2Y8C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C14A family.
messages: Cytoplasm
messages: Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 18 kDa (Caspase-6 subunit p18) and a 11 kDa (Caspase-6 subunit p11) subunit.
messages: Nucleus

93934:EEF1A2
gene id: 93934:EEF1A2
uniprot id: A0A8C2SUT2
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

93934:LOC107312821
gene id: 93934:LOC107312821
uniprot id: A0A8C2YEQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

93934:ITPRIP
gene id: 93934:ITPRIP
uniprot id: A0A8C2YGT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Cell membrane
messages: Enhances Ca(2+)-mediated inhibition of inositol 1,4,5-triphosphate receptor (ITPR) Ca(2+) release.
messages: Membrane
messages: Nucleus outer membrane

93934:PARP9
gene id: 93934:PARP9
uniprot id: A0A8C2YHK3
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:ACO2
gene id: 93934:ACO2
uniprot id: A0A8C2TCG9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.
messages: Mitochondrion

93934:RBBP8
gene id: 93934:RBBP8
uniprot id: A0A8C2T9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COM1/SAE2/CtIP family.
messages: Nucleus

93934:LOC107323840
gene id: 93934:LOC107323840
uniprot id: A0A8C2U4W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:SNX33
gene id: 93934:SNX33
uniprot id: A0A8C2T6W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

93934:SIAH1
gene id: 93934:SIAH1
uniprot id: A0A8C2TUM3
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

93934:RIPPLY2
gene id: 93934:RIPPLY2
uniprot id: A0A8C2SVA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ripply family.
messages: Nucleus

93934:CYRIA
gene id: 93934:CYRIA
uniprot id: A0A8C2TFU7
uniprot id: A0A8C2TJA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYRI family.
messages: Membrane

93934:FLAD1
gene id: 93934:FLAD1
uniprot id: A0A8C2TQR9
names: Function
names: Similarity
messages: Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme.
messages: In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
messages: In the N-terminal section; belongs to the MoaB/Mog family.

93934:SNCG
gene id: 93934:SNCG
uniprot id: A0A8C2YBP4
names: Similarity
names: Subunit
messages: Belongs to the synuclein family.
messages: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation.

93934:TSC22D3
gene id: 93934:TSC22D3
uniprot id: A0A8C2T2C9
names: Similarity
messages: Belongs to the TSC-22/Dip/Bun family.

93934:NIM1K
gene id: 93934:NIM1K
uniprot id: A0A8C2TIC4
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:SSTR1
gene id: 93934:SSTR1
uniprot id: A0A8C2U704
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SGO1
gene id: 93934:SGO1
uniprot id: A0A8C2TN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

93934:MRTO4
gene id: 93934:MRTO4
uniprot id: A0A8C2UA91
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

93934:MED10
gene id: 93934:MED10
uniprot id: A0A8C2TT40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:CD82
gene id: 93934:CD82
uniprot id: A0A8C2TEW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:VDAC2
gene id: 93934:VDAC2
uniprot id: A0A8C2TF59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Mitochondrion outer membrane

93934:MKRN2
gene id: 93934:MKRN2
uniprot id: A0A8C2TPX3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:GPSM2
gene id: 93934:GPSM2
uniprot id: A0A8C2YHM1
names: Similarity
messages: Belongs to the GPSM family.

93934:ACO1
gene id: 93934:ACO1
uniprot id: A0A8C2SVN7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Conversely, when cellular iron levels are high, binds a 4Fe-4S cluster which precludes RNA binding activity and promotes the aconitase activity, the isomerization of citrate to isocitrate via cis-aconitate.
messages: cytosol

93934:RNF2
gene id: 93934:RNF2
uniprot id: A0A8C2UFS0
names: Subcellular Location Annotation
messages: Chromosome
messages: Cytoplasm

93934:LOC107308589
gene id: 93934:LOC107308589
uniprot id: A0A8C2T2L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

93934:TMEM192
gene id: 93934:TMEM192
uniprot id: A0A8C2SMZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM192 family.
messages: Late endosome
messages: Lysosome membrane
messages: Membrane

93934:MED31
gene id: 93934:MED31
uniprot id: A0A8C2U7K4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:NPY4R2
gene id: 93934:NPY4R2
uniprot id: A0A8C2YG24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:HSDL1
gene id: 93934:HSDL1
uniprot id: A0A8C2SLQ9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:HDAC8
gene id: 93934:HDAC8
uniprot id: A0A8C2TG68
names: Similarity
messages: Belongs to the histone deacetylase family. HD type 1 subfamily.

93934:HTR2A
gene id: 93934:HTR2A
uniprot id: A0A8C2UEE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: G-protein coupled receptor for 5-hydroxytryptamine (serotonin).
messages: Membrane
messages: Presynapse
messages: Synapse
messages: Vesicle
messages: axon
messages: caveola
messages: dendrite

93934:GSDME
gene id: 93934:GSDME
uniprot id: A0A8C2TNW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

93934:ETV4
gene id: 93934:ETV4
uniprot id: A0A8C2UB36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:ADIPOR1
gene id: 93934:ADIPOR1
uniprot id: A0A8C2TEQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

93934:PPIL6
gene id: 93934:PPIL6
uniprot id: A0A8C2TD28
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93934:MIS12
gene id: 93934:MIS12
uniprot id: A0A8C2TFK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

93934:TMED4
gene id: 93934:TMED4
uniprot id: A0A8C2YBC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:CAPN10
gene id: 93934:CAPN10
uniprot id: A0A8C2TSI9
names: Similarity
messages: Belongs to the peptidase C2 family.

93934:ESD
gene id: 93934:ESD
uniprot id: A0A8C2UAY5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasmic vesicle
messages: Serine hydrolase involved in the detoxification of formaldehyde.

93934:RPS12
gene id: 93934:RPS12
uniprot id: A0A8C2TBA8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

93934:MANEAL
gene id: 93934:MANEAL
uniprot id: A0A8C2TZ20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 99 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:VPS26A
gene id: 93934:VPS26A
uniprot id: A0A8C2SVE5
names: Similarity
messages: Belongs to the VPS26 family.

93934:GTF2E2
gene id: 93934:GTF2E2
uniprot id: A0A8C2TBH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

93934:LOC107319142
gene id: 93934:LOC107319142
uniprot id: A0A8C2YBL3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

93934:CAT
gene id: 93934:CAT
uniprot id: A0A8C2TXQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
messages: Peroxisome

93934:BDH1
gene id: 93934:BDH1
uniprot id: A0A8C2TK01
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:UBE2C
gene id: 93934:UBE2C
uniprot id: A0A8C2Y821
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:RSBN1L
gene id: 93934:RSBN1L
uniprot id: A0A8C2SY30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the round spermatid basic protein 1 family.
messages: Nucleus

93934:TMEM175
gene id: 93934:TMEM175
uniprot id: A0A8C2TJB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

93934:LOC107312585
gene id: 93934:LOC107312585
uniprot id: A0A8C2T9J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

93934:UCK2
gene id: 93934:UCK2
uniprot id: A0A8C2UKF2
names: Similarity
names: Subunit
messages: Belongs to the uridine kinase family.
messages: Homotetramer.

93934:LOC107317720
gene id: 93934:LOC107317720
uniprot id: A0A8C2TJX1
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

93934:MMP9
gene id: 93934:MMP9
uniprot id: A0A8C2T271
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M10A family.
messages: extracellular matrix

93934:PPT1
gene id: 93934:PPT1
uniprot id: A0A8C2T0I5
names: Similarity
messages: Belongs to the palmitoyl-protein thioesterase family.

93934:NEUROD2
gene id: 93934:NEUROD2
uniprot id: A0A8C2SSG5
names: Subcellular Location Annotation
messages: Nucleus

93934:CHST1
gene id: 93934:CHST1
uniprot id: A0A8C2TRE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

93934:TBX18
gene id: 93934:TBX18
uniprot id: A0A8C2SX10
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:PRPSAP1
gene id: 93934:PRPSAP1
uniprot id: A0A8C2UED0
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

93934:LOC107321366
gene id: 93934:LOC107321366
uniprot id: A0A8C2TRA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:LOC107312032
gene id: 93934:LOC107312032
uniprot id: A0A8C2Y888
names: Similarity
messages: Belongs to the cytochrome c oxidase VIIa family.

93934:CACNB2
gene id: 93934:CACNB2
uniprot id: A0A8C2SWJ0
uniprot id: A0A8C2SWT7
uniprot id: A0A8C2SWU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calcium channel beta subunit family.
messages: The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
messages: sarcolemma

93934:NPC1
gene id: 93934:NPC1
uniprot id: A0A8C2TCK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

93934:CSTF3
gene id: 93934:CSTF3
uniprot id: A0A8C2TUK8
names: Subcellular Location Annotation
messages: Nucleus

93934:DAG1
gene id: 93934:DAG1
uniprot id: A0A8C2YAM3
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization.
messages: Transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity.
messages: extracellular space
messages: nucleoplasm
messages: sarcolemma

93934:PELI2
gene id: 93934:PELI2
uniprot id: A0A8C2T5N1
names: Similarity
messages: Belongs to the pellino family.

93934:LOC107312830
gene id: 93934:LOC107312830
uniprot id: A0PAT8
uniprot id: A1IHM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:RSRP1
gene id: 93934:RSRP1
uniprot id: A0A8C2YEA4
names: Similarity
messages: Belongs to the RSRP family.

93934:KAT2A
gene id: 93934:KAT2A
uniprot id: A0A8C2T0A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus
messages: centrosome

93934:PTER
gene id: 93934:PTER
uniprot id: A0A8C2SZB9
names: Caution
names: Cofactor
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
messages: Binds 2 divalent metal cations per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:BLCAP
gene id: 93934:BLCAP
uniprot id: A0A8C2UCR5
names: Similarity
messages: Belongs to the BLCAP family.

93934:OCIAD1
gene id: 93934:OCIAD1
uniprot id: A0A8C2TH15
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OCIAD1 family.
messages: Endosome
messages: Interacts with STAT3.
messages: Maintains stem cell potency. Increases STAT3 phosphorylation and controls ERK phosphorylation. May act as a scaffold, increasing STAT3 recruitment onto endosomes.
messages: The OCIA domain is necessary and sufficient for endosomal localization.

93934:TUT7
gene id: 93934:TUT7
uniprot id: A0A8C2TCZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B-like family.
messages: Cytoplasm

93934:ACE
gene id: 93934:ACE
uniprot id: A0A8C2U6U5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M2 family.
messages: Binds 2 Zn(2+) ions per subunit.

93934:SLC8B1
gene id: 93934:SLC8B1
uniprot id: A0A8C2TVJ3
uniprot id: A0A8C2TY00
names: Subcellular Location Annotation
messages: Membrane

93934:STEAP2
gene id: 93934:STEAP2
uniprot id: A0A8C2T507
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

93934:AOX1
gene id: 93934:AOX1
uniprot id: A0A8C2TXL1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the xanthine dehydrogenase family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Binds 2 [2Fe-2S] clusters.
messages: Cytoplasm
messages: Homodimer.

93934:CHM
gene id: 93934:CHM
uniprot id: A0A8C2U2I3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab GDI family.
messages: Cytoplasm
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

93934:KAT7
gene id: 93934:KAT7
uniprot id: A0A8C2U9M4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYST (SAS/MOZ) family.
messages: Nucleus

93934:DLGAP2
gene id: 93934:DLGAP2
uniprot id: A0A8C2T6M5
uniprot id: A0A8C2T7D9
names: Similarity
messages: Belongs to the SAPAP family.

93934:UST
gene id: 93934:UST
uniprot id: A0A8C2T2U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 3 family.
messages: Membrane

93934:LIN54
gene id: 93934:LIN54
uniprot id: A0A8C2TCJ4
uniprot id: A0A8C2TGA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-54 family.
messages: Nucleus

93934:TP53I11
gene id: 93934:TP53I11
uniprot id: A0A8C2TEX7
names: Subcellular Location Annotation
messages: Membrane

93934:RNFT2
gene id: 93934:RNFT2
uniprot id: A0A8C2TW77
names: Subcellular Location Annotation
messages: Membrane

93934:DBX1
gene id: 93934:DBX1
uniprot id: A0A8C2YD74
names: Subcellular Location Annotation
messages: Nucleus

93934:STK11
gene id: 93934:STK11
uniprot id: A0A8C2TGW0
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. LKB1 subfamily.

93934:PIGP
gene id: 93934:PIGP
uniprot id: A0A8C2TAY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGP family.
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

93934:MMS22L
gene id: 93934:MMS22L
uniprot id: A0A8C2SMX0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MMS22 family. MMS22L subfamily.
messages: Chromosome
messages: Nucleus

93934:C1H11orf54
gene id: 93934:C1H11orf54
uniprot id: A0A8C2SWC1
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
messages: Monomer.
messages: Nucleus

93934:AIMP2
gene id: 93934:AIMP2
uniprot id: A0A8C2YCF6
names: Subcellular Location Annotation
messages: Nucleus
messages: cytosol

93934:MIPEP
gene id: 93934:MIPEP
uniprot id: A0A8C2SMW7
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

93934:EPHB1
gene id: 93934:EPHB1
uniprot id: A0A8C2U7F3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: dendrite

93934:LOC107318039
gene id: 93934:LOC107318039
uniprot id: A0A8C2T6D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Membrane

93934:HNRNPK
gene id: 93934:HNRNPK
uniprot id: A0A8C2Y9S6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleoplasm

93934:ASXL2
gene id: 93934:ASXL2
uniprot id: A0A8C2TPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

93934:NOL6
gene id: 93934:NOL6
uniprot id: A0A8C2Y7J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

93934:TFCP2
gene id: 93934:TFCP2
uniprot id: A0A8C2SZ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the grh/CP2 family. CP2 subfamily.
messages: Nucleus

93934:DLK2
gene id: 93934:DLK2
uniprot id: A0A8C2TJ19
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:AP3M2
gene id: 93934:AP3M2
uniprot id: A0A8C2TWG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus

93934:NUMB
gene id: 93934:NUMB
uniprot id: A0A8C2YDE0
uniprot id: A0A8C2YDG6
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Plays a role in the process of neurogenesis.

93934:LYPD6B
gene id: 93934:LYPD6B
uniprot id: A0A8C2UC84
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:LOC107314491
gene id: 93934:LOC107314491
uniprot id: A0A8C2U910
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.
messages: Monomer. Homodimer; disulfide-linked.
messages: Secreted
messages: The N- and C-terminal barrels adopt an identical fold despite having only 13% of conserved residues.
messages: The N-terminal region may be exposed to the interior of the granule, whereas the C-terminal portion may be embedded in the membrane. During phagocytosis and degranulation, proteases may be released and activated and cleave BPI at the junction of the N- and C-terminal portions of the molecule, providing controlled release of the N-terminal antibacterial fragment when bacteria are ingested.
messages: The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope.

93934:MLEC
gene id: 93934:MLEC
uniprot id: A0A8C2TNL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the malectin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TAFA1
gene id: 93934:TAFA1
uniprot id: A0A8C2U6R0
names: Similarity
messages: Belongs to the TAFA family.

93934:RARS1
gene id: 93934:RARS1
uniprot id: A0A8C2TAV6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:MYH15
gene id: 93934:MYH15
uniprot id: A0A8C2U1N6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:MFNG
gene id: 93934:MFNG
uniprot id: A0A8C2YCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:EN2
gene id: 93934:EN2
uniprot id: A0A8C2SRW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

93934:TADA1
gene id: 93934:TADA1
uniprot id: A0A8C2UJW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TADA1 family.
messages: Nucleus
messages: Probably involved in transcriptional regulation.

93934:UBA52
gene id: 93934:UBA52
uniprot id: A0A8C2THV3
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

93934:NRG3
gene id: 93934:NRG3
uniprot id: A0A8C2TL98
names: Caution
names: Similarity
messages: Belongs to the neuregulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107314084
gene id: 93934:LOC107314084
uniprot id: A0A8C2T854
names: Subcellular Location Annotation
messages: Nucleus

93934:ATG16L1
gene id: 93934:ATG16L1
uniprot id: A0A8C2TY99
uniprot id: A0A8C2U1I1
names: Similarity
messages: Belongs to the WD repeat ATG16 family.

93934:SMIM18
gene id: 93934:SMIM18
uniprot id: A0A8C2T937
names: Subcellular Location Annotation
messages: Membrane

93934:LPAR6
gene id: 93934:LPAR6
uniprot id: A0A8C2UAZ1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:FAM167A
gene id: 93934:FAM167A
uniprot id: A0A8C2SLW4
names: Similarity
messages: Belongs to the FAM167 (SEC) family.

93934:LOC107319528
gene id: 93934:LOC107319528
uniprot id: A0A8C2TTM8
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:C25H1orf43
gene id: 93934:C25H1orf43
uniprot id: A0A8C2TQX0
names: Function
names: Subcellular Location Annotation
messages: General regulator of phagocytosis. Required to uptake Gram negative bacterium by macrophages.
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion

93934:ZFYVE27
gene id: 93934:ZFYVE27
uniprot id: A0A8C2U7U3
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: growth cone membrane

93934:ETV1
gene id: 93934:ETV1
uniprot id: A0A8C2TII0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:FCF1
gene id: 93934:FCF1
uniprot id: A0A8C2U754
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

93934:LOC107325172
gene id: 93934:LOC107325172
uniprot id: A0A8C2U7X3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with GIRK2, GIRK3 or GIRK4 to form a G-protein activated heteromultimer pore-forming unit. The resulting inward current is much larger.
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ3 subfamily.
messages: Membrane
messages: This potassium channel is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This receptor plays a crucial role in regulating the heartbeat.

93934:CLTRN
gene id: 93934:CLTRN
uniprot id: A0A8C2YFI5
names: Subcellular Location Annotation
messages: Membrane

93934:CSMD3
gene id: 93934:CSMD3
uniprot id: A0A8C2T011
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PKNOX1
gene id: 93934:PKNOX1
uniprot id: A0A8C2TC35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/MEIS homeobox family.
messages: Nucleus

93934:SLC16A10
gene id: 93934:SLC16A10
uniprot id: A0A8C2Y9U6
names: Subcellular Location Annotation
messages: Membrane

93934:PDK3
gene id: 93934:PDK3
uniprot id: A0A8C2U3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

93934:EMC8
gene id: 93934:EMC8
uniprot id: A0A8C2TTC0
names: Similarity
messages: Belongs to the EMC8/EMC9 family.

93934:LOC107312499
gene id: 93934:LOC107312499
uniprot id: A0A8C2TR70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

93934:KCNN3
gene id: 93934:KCNN3
uniprot id: A0A8C2YD03
names: Subcellular Location Annotation
messages: Membrane

93934:GOLM2
gene id: 93934:GOLM2
uniprot id: A0A8C2UFW1
uniprot id: A0A8C2YHM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLM family.
messages: Membrane

93934:SHQ1
gene id: 93934:SHQ1
uniprot id: A0A8C2UAJ7
names: Similarity
messages: Belongs to the SHQ1 family.

93934:TFB2M
gene id: 93934:TFB2M
uniprot id: A0A8C2TPS4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

93934:QARS1
gene id: 93934:QARS1
uniprot id: A0A8C2YEI8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:SERINC2
gene id: 93934:SERINC2
uniprot id: A0A8C2YDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

93934:CS
gene id: 93934:CS
uniprot id: A0A8C2Y729
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the citrate synthase family.
messages: Homodimer.
messages: Mitochondrion matrix

93934:S100A10
gene id: 93934:S100A10
uniprot id: A0A8C2SKL0
names: Function
messages: Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase.

93934:NELL2
gene id: 93934:NELL2
uniprot id: A0A8C2TN35
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:HAT1
gene id: 93934:HAT1
uniprot id: A0A8C2U280
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic subunit of the type B histone acetyltransferase (HAT) complex, composed of RBBP7 and HAT1. Interacts with histones H4 and H2A.
messages: Histone acetyltransferase that plays a role in different biological processes including cell cycle progression, glucose metabolism, histone production or DNA damage repair. Coordinates histone production and acetylation via H4 promoter binding. Acetylates histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, histone H2A at 'Lys-5' (H2AK5ac).

93934:DDX27
gene id: 93934:DDX27
uniprot id: A0A8C2T2G0
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:PPP4R2
gene id: 93934:PPP4R2
uniprot id: A0A8C2UA40
names: Similarity
messages: Belongs to the PPP4R2 family.

93934:UPP1
gene id: 93934:UPP1
uniprot id: A0A8C2TTR6
names: Function
names: Similarity
messages: Belongs to the PNP/UDP phosphorylase family.
messages: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

93934:EXOSC2
gene id: 93934:EXOSC2
uniprot id: A0A8C2Y5G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

93934:TIGD5
gene id: 93934:TIGD5
uniprot id: A0A8C2THE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tigger transposable element derived protein family.
messages: Nucleus

93934:NFIC
gene id: 93934:NFIC
uniprot id: A0A8C2T5M2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

93934:CTSO
gene id: 93934:CTSO
uniprot id: A0A8C2Y510
names: Similarity
messages: Belongs to the peptidase C1 family.

93934:TBX20
gene id: 93934:TBX20
uniprot id: A0A8C2T258
uniprot id: A0A8C2T4Z2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:DDX20
gene id: 93934:DDX20
uniprot id: A0A8C2U254
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:MDFIC
gene id: 93934:MDFIC
uniprot id: A0A8C2TLN1
names: Similarity
messages: Belongs to the MDFI family.

93934:LOC107319203
gene id: 93934:LOC107319203
uniprot id: A0A8C2TKA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:GLA
gene id: 93934:GLA
uniprot id: A0A8C2TGI1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

93934:LOC107312756
gene id: 93934:LOC107312756
uniprot id: A0A8C2U008
names: Subcellular Location Annotation
messages: Nucleus

93934:TUBB4B
gene id: 93934:TUBB4B
uniprot id: A0A8C2U400
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

93934:CDO1
gene id: 93934:CDO1
uniprot id: A0A8C2T2W2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the cysteine dioxygenase family.
messages: Binds 1 Fe cation per subunit.
messages: Catalyzes the oxidation of cysteine to cysteine sulfinic acid with addition of molecular dioxygen.

93934:AQP11
gene id: 93934:AQP11
uniprot id: A0A8C2Y6R5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

93934:PRKCE
gene id: 93934:PRKCE
uniprot id: A0A8C2TF87
uniprot id: A0A8C2TFK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

93934:HSPB3
gene id: 93934:HSPB3
uniprot id: A0A8C2SPT4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93934:FAM174B
gene id: 93934:FAM174B
uniprot id: A0A8C2UFI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM174 family.
messages: Membrane

93934:LOC107309791
gene id: 93934:LOC107309791
uniprot id: A0A8C2U339
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

93934:AQP5
gene id: 93934:AQP5
uniprot id: A0A8C2SV83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93934:RAD51
gene id: 93934:RAD51
uniprot id: A0A8C2TP33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Also involved in interstrand cross-link repair.

93934:SLC5A12
gene id: 93934:SLC5A12
uniprot id: A0A8C2TUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:HCFC2
gene id: 93934:HCFC2
uniprot id: A0A8C2U3U6
names: Subcellular Location Annotation
messages: Nucleus

93934:TRMT5
gene id: 93934:TRMT5
uniprot id: A0A8C2SYL8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

93934:LOC107308597
gene id: 93934:LOC107308597
uniprot id: A0A8C2Y7J6
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

93934:DNAJA2
gene id: 93934:DNAJA2
uniprot id: A0A8C2TR11
names: Subcellular Location Annotation
messages: Membrane

93934:NOS2
gene id: 93934:NOS2
uniprot id: A0A8C2U639
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NOS family.
messages: Binds 1 FAD.
messages: Binds 1 FMN.
messages: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body.

93934:EN1
gene id: 93934:EN1
uniprot id: A0A8C2UFI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Engrailed homeobox family.
messages: Nucleus

93934:IER3IP1
gene id: 93934:IER3IP1
uniprot id: A0A8C2SXJ9
names: Similarity
messages: Belongs to the YOS1 family.

93934:UBE2N
gene id: 93934:UBE2N
uniprot id: A0A8C2SZ23
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:ZNF532
gene id: 93934:ZNF532
uniprot id: A0A8C2SWZ2
uniprot id: A0A8C2SWZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: May be involved in transcriptional regulation.
messages: Nucleus

93934:LOC107323633
gene id: 93934:LOC107323633
uniprot id: A0A8C2TI22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ACDP family.
messages: Membrane

93934:GAB2
gene id: 93934:GAB2
uniprot id: A0A8C2SVT0
names: Similarity
messages: Belongs to the GAB family.

93934:SNX30
gene id: 93934:SNX30
uniprot id: A0A8C2SNA4
names: Similarity
messages: Belongs to the sorting nexin family.

93934:NDRG1
gene id: 93934:NDRG1
uniprot id: A0A8C2YA80
names: Similarity
messages: Belongs to the NDRG family.

93934:AOPEP
gene id: 93934:AOPEP
uniprot id: A0A8C2TAN0
names: Similarity
messages: Belongs to the peptidase M1 family.

93934:ROR1
gene id: 93934:ROR1
uniprot id: A0A8C2TUD3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:EPS8
gene id: 93934:EPS8
uniprot id: A0A8C2SR71
names: Similarity
messages: Belongs to the EPS8 family.

93934:MCL1
gene id: 93934:MCL1
uniprot id: A0A8C2TWR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Membrane
messages: nucleoplasm

93934:OTP
gene id: 93934:OTP
uniprot id: A0A8C2Y8W3
names: Subcellular Location Annotation
messages: Nucleus

93934:RRM2
gene id: 93934:RRM2
uniprot id: A0A8C2TFV1
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

93934:FAT1
gene id: 93934:FAT1
uniprot id: A0A8C2T5A0
uniprot id: A0A8C2T6U1
uniprot id: A0A8C2Y8I1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:OPRM1
gene id: 93934:OPRM1
uniprot id: A0A8C2T7B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Perikaryon
messages: axon
messages: dendrite

93934:INTS9
gene id: 93934:INTS9
uniprot id: A0A8C2TPH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. INTS9 subfamily.
messages: Nucleus

93934:UBE2F
gene id: 93934:UBE2F
uniprot id: A0A8C2TV81
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:TMEM87A
gene id: 93934:TMEM87A
uniprot id: A0A8C2TRC2
names: Subcellular Location Annotation
messages: Membrane

93934:ATP5PF
gene id: 93934:ATP5PF
uniprot id: A0A8C2SXM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ATPase subunit F6 family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. Also involved in the restoration of oligomycin-sensitive ATPase activity to depleted F1-F0 complexes.
messages: Mitochondrion
messages: Mitochondrion inner membrane

93934:LOC107314004
gene id: 93934:LOC107314004
uniprot id: A0A8C2TS77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

93934:CTNNA1
gene id: 93934:CTNNA1
uniprot id: A0A8C2TGV5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction
messages: cytoskeleton

93934:SEC23B
gene id: 93934:SEC23B
uniprot id: A0A8C2SYV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

93934:API5
gene id: 93934:API5
uniprot id: A0A8C2TEV5
names: Similarity
messages: Belongs to the API5 family.

93934:AHR
gene id: 93934:AHR
uniprot id: D7REZ2
names: Subcellular Location Annotation
messages: Cytoplasm

93934:LARS2
gene id: 93934:LARS2
uniprot id: A0A8C2SVG4
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:TRAPPC2
gene id: 93934:TRAPPC2
uniprot id: A0A8C2YFK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. Sedlin subfamily.
messages: perinuclear region

93934:GBX2
gene id: 93934:GBX2
uniprot id: A0A8C2TRX0
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107323794
gene id: 93934:LOC107323794
uniprot id: A0A8C2TX26
names: Similarity
messages: Belongs to the nucleoplasmin family.

93934:GHITM
gene id: 93934:GHITM
uniprot id: A0A8C2TNY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93934:CEP162
gene id: 93934:CEP162
uniprot id: A0A8C2SV57
uniprot id: A0A8C2SVJ6
uniprot id: A0A8C2SY64
uniprot id: A0A8C2Y6L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CEP162 family.
messages: centriole

93934:TTC4
gene id: 93934:TTC4
uniprot id: A0A8C2TJY1
names: Similarity
messages: Belongs to the TTC4 family.

93934:NAMPT
gene id: 93934:NAMPT
uniprot id: A0A8C2T400
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAPRTase family.
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Secreted

93934:FGFBP2
gene id: 93934:FGFBP2
uniprot id: A0A8C2U853
names: Similarity
messages: Belongs to the fibroblast growth factor-binding protein family.

93934:LOC107310823
gene id: 93934:LOC107310823
uniprot id: A0A8C2U079
names: Similarity
messages: Belongs to the CRISP family.

93934:B3GNT7
gene id: 93934:B3GNT7
uniprot id: A0A8C2TT51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:CD151
gene id: 93934:CD151
uniprot id: A0A8C2U8E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:LIPI
gene id: 93934:LIPI
uniprot id: A0A8C2Y6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

93934:CDR2
gene id: 93934:CDR2
uniprot id: A0A8C2TUZ4
names: Similarity
messages: Belongs to the CDR2 family.

93934:RARA
gene id: 93934:RARA
uniprot id: A0A8C2SR12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:LOC107312614
gene id: 93934:LOC107312614
uniprot id: A0A8C2T146
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

93934:TCTN1
gene id: 93934:TCTN1
uniprot id: A0A8C2UD36
names: Similarity
names: Subunit
messages: Belongs to the tectonic family.
messages: Part of the tectonic-like complex (also named B9 complex).

93934:DGAT2
gene id: 93934:DGAT2
uniprot id: A0A8C2SZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Endoplasmic reticulum membrane

93934:ESRP2
gene id: 93934:ESRP2
uniprot id: A0A8C2YBV0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESRP family.
messages: Nucleus

93934:C1D
gene id: 93934:C1D
uniprot id: A0A8C2TH32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the C1D family.
messages: Cytoplasm
messages: Monomer and homodimer.
messages: Nucleus
messages: Plays a role in the recruitment of the exosome to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA.
messages: nucleolus

93934:RAN
gene id: 93934:RAN
uniprot id: A0A8C2UAI6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

93934:CACNG3
gene id: 93934:CACNG3
uniprot id: A0A8C2TFI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane

93934:TP73
gene id: 93934:TP73
uniprot id: A0A8C2TCN8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Found in a complex with p53/TP53 and CABLES1.
messages: Nucleus
messages: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

93934:EIF4E3
gene id: 93934:EIF4E3
uniprot id: A0A8C2U906
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

93934:IMPACT
gene id: 93934:IMPACT
uniprot id: A0A8C2TEE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

93934:SLC25A24
gene id: 93934:SLC25A24
uniprot id: A0A8C2YHL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

93934:AMIGO2
gene id: 93934:AMIGO2
uniprot id: A0A8C2YCI4
names: Similarity
messages: Belongs to the immunoglobulin superfamily. AMIGO family.

93934:CPLX3
gene id: 93934:CPLX3
uniprot id: A0A8C2T729
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

93934:LOC107321829
gene id: 93934:LOC107321829
uniprot id: A0A8C2UEN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.
messages: Endoplasmic reticulum lumen

93934:ACTR2
gene id: 93934:ACTR2
uniprot id: A0A8C2TH76
names: Similarity
messages: Belongs to the actin family.

93934:PHOSPHO1
gene id: 93934:PHOSPHO1
uniprot id: A0A8C2U7Y9
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. PHOSPHO family.

93934:SHROOM2
gene id: 93934:SHROOM2
uniprot id: A0A8C2U3W9
uniprot id: A0A8C2U764
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

93934:RNF7
gene id: 93934:RNF7
uniprot id: A0A8C2TDY4
names: Similarity
messages: Belongs to the RING-box family.

93934:NDUFV2
gene id: 93934:NDUFV2
uniprot id: A0A8C2Y940
names: Function
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor.

93934:MYT1
gene id: 93934:MYT1
uniprot id: A0A8C2SV40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MYT1 family.
messages: Nucleus

93934:CDH20
gene id: 93934:CDH20
uniprot id: A0A8C2TUV9
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:SLC30A5
gene id: 93934:SLC30A5
uniprot id: A0A8C2Y939
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Functions as a zinc transporter.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: trans-Golgi network membrane

93934:SLC45A2
gene id: 93934:SLC45A2
uniprot id: A0A8C2T6T6
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107308112
gene id: 93934:LOC107308112
uniprot id: A0A8C2T987
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Membrane

93934:CDH22
gene id: 93934:CDH22
uniprot id: A0A8C2T3G2
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:MAGI3
gene id: 93934:MAGI3
uniprot id: A0A8C2U3Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Cell membrane
messages: Membrane
messages: tight junction

93934:TOB1
gene id: 93934:TOB1
uniprot id: A0A8C2UGP9
names: Similarity
messages: Belongs to the BTG family.

93934:BCLAF1
gene id: 93934:BCLAF1
uniprot id: A0A8C2TBS0
names: Similarity
messages: Belongs to the BCLAF1/THRAP3 family.

93934:RAB27A
gene id: 93934:RAB27A
uniprot id: A0A8C2U0K4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Endosome
messages: Late endosome
messages: Membrane

93934:TRAF2
gene id: 93934:TRAF2
uniprot id: A0A8C2TYE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

93934:CTDP1
gene id: 93934:CTDP1
uniprot id: A0A8C2U318
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

93934:BECN1
gene id: 93934:BECN1
uniprot id: A0A8C2T0F6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beclin family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Endosome membrane
messages: Membrane
messages: Mitochondrion membrane
messages: Plays a central role in autophagy.
messages: autophagosome
messages: trans-Golgi network membrane

93934:KCNJ16
gene id: 93934:KCNJ16
uniprot id: A0A8C2UHN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

93934:SPTY2D1
gene id: 93934:SPTY2D1
uniprot id: A0A8C2TEU0
names: Similarity
messages: Belongs to the SPT2 family.

93934:LOC107321151
gene id: 93934:LOC107321151
uniprot id: A0A8C2T2X5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:EP300
gene id: 93934:EP300
uniprot id: A0A8C2TAM3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:CRABP1
gene id: 93934:CRABP1
uniprot id: A0A8C2T978
names: Function
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
messages: Cytosolic CRABPs may regulate the access of retinoic acid to the nuclear retinoic acid receptors.

93934:MAFF
gene id: 93934:MAFF
uniprot id: A0A8C2TSY3
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

93934:MLF1
gene id: 93934:MLF1
uniprot id: A0A8C2U888
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLF family.
messages: Cytoplasm

93934:LYAR
gene id: 93934:LYAR
uniprot id: A0A8C2U6D9
names: Subcellular Location Annotation
messages: Cytoplasm

93934:C17H9orf116
gene id: 93934:C17H9orf116
uniprot id: A0A8C2T8G7
names: Subcellular Location Annotation
messages: cilium axoneme

93934:EVA1A
gene id: 93934:EVA1A
uniprot id: A0A8C2Y5S2
names: Similarity
messages: Belongs to the EVA1 family.

93934:WDR82
gene id: 93934:WDR82
uniprot id: A0A8C2TH53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SWD2 family.
messages: Nucleus

93934:TUBB6
gene id: 93934:TUBB6
uniprot id: A0A8C2T832
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

93934:ANTXRL
gene id: 93934:ANTXRL
uniprot id: A0A8C2UBB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

93934:LOC107312882
gene id: 93934:LOC107312882
uniprot id: A0A8C2TZB5
names: Similarity
messages: Belongs to the SUA5 family.

93934:TGIF1
gene id: 93934:TGIF1
uniprot id: A0A8C2TBC7
names: Subcellular Location Annotation
messages: Nucleus

93934:NOC2L
gene id: 93934:NOC2L
uniprot id: A0A8C2TJ95
names: Similarity
messages: Belongs to the NOC2 family.

93934:FARS2
gene id: 93934:FARS2
uniprot id: A0A8C2U2Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

93934:ACTG1
gene id: 93934:ACTG1
uniprot id: A0A8C2UDR3
names: Similarity
messages: Belongs to the actin family.

93934:TSHZ2
gene id: 93934:TSHZ2
uniprot id: A0A8C2T663
names: Similarity
messages: Belongs to the teashirt C2H2-type zinc-finger protein family.

93934:HARBI1
gene id: 93934:HARBI1
uniprot id: A0A8C2TPE6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HARBI1 family.
messages: Cytoplasm
messages: Nucleus
messages: Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.

93934:TFAP2B
gene id: 93934:TFAP2B
uniprot id: A0A8C2SQL8
names: Similarity
messages: Belongs to the AP-2 family.

93934:ZIC3
gene id: 93934:ZIC3
uniprot id: A0A8C2TXU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

93934:SS18L2
gene id: 93934:SS18L2
uniprot id: A0A8C2YDA8
names: Similarity
messages: Belongs to the SS18 family.

93934:PHC3
gene id: 93934:PHC3
uniprot id: A0A8C2U2L4
uniprot id: A0A8C2U6J1
names: Subcellular Location Annotation
messages: Nucleus

93934:EDA
gene id: 93934:EDA
uniprot id: A0A8C2SRK2
names: Similarity
messages: Belongs to the tumor necrosis factor family.

93934:CERS6
gene id: 93934:CERS6
uniprot id: A0A8C2UCG9
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

93934:SS18L1
gene id: 93934:SS18L1
uniprot id: A0A8C2SSP4
names: Similarity
messages: Belongs to the SS18 family.

93934:LOC107314940
gene id: 93934:LOC107314940
uniprot id: A0A8C2U7L2
names: Similarity
messages: Belongs to the aldo/keto reductase family.

93934:GGA3
gene id: 93934:GGA3
uniprot id: A0A8C2UHD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GGA protein family.
messages: Early endosome membrane
messages: Endosome membrane
messages: trans-Golgi network membrane

93934:NMT1
gene id: 93934:NMT1
uniprot id: A0A8C2U6E9
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

93934:PSIP1
gene id: 93934:PSIP1
uniprot id: A0A8C2T6S2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

93934:MAN2A2
gene id: 93934:MAN2A2
uniprot id: A0A8C2SK91
uniprot id: A0A8C2SKA2
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

93934:OTX2
gene id: 93934:OTX2
uniprot id: A0A8C2Y7R6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family. Bicoid subfamily.
messages: Nucleus

93934:MAFA
gene id: 93934:MAFA
uniprot id: A0A8C2TGY9
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

93934:LHX4
gene id: 93934:LHX4
uniprot id: A0A8C2UJ21
names: Subcellular Location Annotation
messages: Nucleus

93934:UFD1
gene id: 93934:UFD1
uniprot id: A0A8C2U8X9
names: Similarity
messages: Belongs to the UFD1 family.

93934:TAFA2
gene id: 93934:TAFA2
uniprot id: A0A8C2TRL2
names: Similarity
messages: Belongs to the TAFA family.

93934:TAF2
gene id: 93934:TAF2
uniprot id: A0A8C2SZ37
uniprot id: A0A8C2T0P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF2 family.
messages: Nucleus

93934:ORC6
gene id: 93934:ORC6
uniprot id: A0A8C2TTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

93934:TK1
gene id: 93934:TK1
uniprot id: A0A8C2UJE2
names: Similarity
messages: Belongs to the thymidine kinase family.

93934:MELTF
gene id: 93934:MELTF
uniprot id: A0A8C2TJT0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

93934:TAF15
gene id: 93934:TAF15
uniprot id: A0A8C2THB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM TET family.
messages: Nucleus

93934:ELAVL4
gene id: 93934:ELAVL4
uniprot id: A0A8C2YAC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm
messages: Perikaryon
messages: axon
messages: dendrite
messages: growth cone

93934:EPYC
gene id: 93934:EPYC
uniprot id: A0A8C2SXG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: extracellular matrix

93934:SH3BP4
gene id: 93934:SH3BP4
uniprot id: A0A8C2TPE5
names: Subcellular Location Annotation
messages: Nucleus
messages: Vesicle
messages: clathrin-coated pit
messages: clathrin-coated vesicle

93934:ADGRL2
gene id: 93934:ADGRL2
uniprot id: A0A8C2T7B0
names: Subcellular Location Annotation
messages: Membrane

93934:BMPR2
gene id: 93934:BMPR2
uniprot id: A0A8C2YDM7
names: Similarity
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.

93934:TPST2
gene id: 93934:TPST2
uniprot id: A0A8C2T7X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein sulfotransferase family.
messages: Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate.
messages: Golgi apparatus membrane

93934:LUC7L3
gene id: 93934:LUC7L3
uniprot id: A0A8C2UGZ7
names: Similarity
messages: Belongs to the Luc7 family.

93934:MRPL43
gene id: 93934:MRPL43
uniprot id: A0A8C2UBX5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

93934:TRMT1L
gene id: 93934:TRMT1L
uniprot id: A0A8C2YHX1
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
messages: May play a role in motor coordination and exploratory behavior.

93934:RBX1
gene id: 93934:RBX1
uniprot id: A0A8C2TDB7
names: Similarity
messages: Belongs to the RING-box family.

93934:MC4R
gene id: 93934:MC4R
uniprot id: A0A8C2TV83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).

93934:LOC107312539
gene id: 93934:LOC107312539
uniprot id: A0A8C2Y977
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:MATN2
gene id: 93934:MATN2
uniprot id: A0A8C2SNP7
uniprot id: A0A8C2Y535
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:OXCT1
gene id: 93934:OXCT1
uniprot id: A0A8C2TI75
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-oxoacid CoA-transferase family.
messages: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
messages: Mitochondrion

93934:MYLK2
gene id: 93934:MYLK2
uniprot id: A0A8C2T1T9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
messages: Cytoplasm
messages: May interact with centrin.

93934:VEGFD
gene id: 93934:VEGFD
uniprot id: A0A8C2U8W8
uniprot id: A0A8C2YFK2
names: Similarity
messages: Belongs to the PDGF/VEGF growth factor family.

93934:PUS3
gene id: 93934:PUS3
uniprot id: A0A8C2T2A6
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

93934:P2RX5
gene id: 93934:P2RX5
uniprot id: A0A8C2YDZ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the P2X receptor family.
messages: Functional P2XRs are organized as homomeric and heteromeric trimers.
messages: Membrane
messages: Receptor for ATP that acts as a ligand-gated ion channel.

93934:KARS1
gene id: 93934:KARS1
uniprot id: A0A8C2Y6Q9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

93934:LOC107312442
gene id: 93934:LOC107312442
uniprot id: A0A8C2SQI0
names: Caution
names: Similarity
messages: Belongs to the CRISP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:FGGY
gene id: 93934:FGGY
uniprot id: A0A8C2YBV8
names: Similarity
messages: Belongs to the FGGY kinase family.

93934:DDC
gene id: 93934:DDC
uniprot id: A0A8C2TW40
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

93934:MNAT1
gene id: 93934:MNAT1
uniprot id: A0A8C2SYM8
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Associates with CDK7 and cyclin H.
messages: Nucleus
messages: Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.

93934:CDC26
gene id: 93934:CDC26
uniprot id: A0A8C2TYT7
names: Similarity
messages: Belongs to the CDC26 family.

93934:MTFR1
gene id: 93934:MTFR1
uniprot id: A0A8C2YBB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTFR1 family.
messages: Mitochondrion
messages: Plays a role in mitochondrial aerobic respiration. Regulates mitochondrial organization and fission.

93934:LHX9
gene id: 93934:LHX9
uniprot id: A0A8C2UDL3
names: Subcellular Location Annotation
messages: Nucleus

93934:CHST13
gene id: 93934:CHST13
uniprot id: A0A8C2TXE4
uniprot id: A0A8C2TZL6
uniprot id: A0A8C2U0T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:LDLRAD4
gene id: 93934:LDLRAD4
uniprot id: A0A8C2T5U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMEPA1 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

93934:ST8SIA6
gene id: 93934:ST8SIA6
uniprot id: A0A8C2T1K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:A2M
gene id: 93934:A2M
uniprot id: A0A8C2U255
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

93934:GPBP1
gene id: 93934:GPBP1
uniprot id: A0A8C2SRA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

93934:CNMD
gene id: 93934:CNMD
uniprot id: A0A8C2UAT7
names: Similarity
messages: Belongs to the chondromodulin-1 family.

93934:GRHL1
gene id: 93934:GRHL1
uniprot id: A0A8C2TFM9
names: Subcellular Location Annotation
messages: Nucleus

93934:PLPP3
gene id: 93934:PLPP3
uniprot id: A0A8C2TJD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

93934:RNF20
gene id: 93934:RNF20
uniprot id: A0A8C2Y549
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

93934:LOC107306547
gene id: 93934:LOC107306547
uniprot id: A0A8C2TN75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

93934:FXN
gene id: 93934:FXN
uniprot id: A0A8C2T618
names: Similarity
messages: Belongs to the frataxin family.

93934:GDPD4
gene id: 93934:GDPD4
uniprot id: A0A8C2SXU8
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

93934:ZC3H15
gene id: 93934:ZC3H15
uniprot id: A0A8C2TPB4
names: Similarity
messages: Belongs to the ZC3H15/TMA46 family.

93934:HDHD2
gene id: 93934:HDHD2
uniprot id: A0A8C2Y705
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

93934:INTS13
gene id: 93934:INTS13
uniprot id: A0A8C2TQH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the asunder family.
messages: Cytoplasm
messages: Nucleus

93934:CASP3
gene id: 93934:CASP3
uniprot id: A0A8C2TDQ4
names: Similarity
messages: Belongs to the peptidase C14A family.

93934:SOAT1
gene id: 93934:SOAT1
uniprot id: A0A8C2UGN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107325529
gene id: 93934:LOC107325529
uniprot id: A0A8C2T0J7
uniprot id: A0A8C2T5I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Membrane

93934:STOM
gene id: 93934:STOM
uniprot id: A0A8C2YAE9
names: Similarity
messages: Belongs to the band 7/mec-2 family.

93934:GSPT1
gene id: 93934:GSPT1
uniprot id: A0A8C2TNC1
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

93934:CALHM5
gene id: 93934:CALHM5
uniprot id: A0A8C2Y9U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

93934:GGT7
gene id: 93934:GGT7
uniprot id: A0A8C2UAG7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.
messages: Membrane

93934:TMEM53
gene id: 93934:TMEM53
uniprot id: A0A8C2TH05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM53 family.
messages: Membrane
messages: Nucleus outer membrane

93934:ONECUT3
gene id: 93934:ONECUT3
uniprot id: A0A8C2TDI2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

93934:QSOX2
gene id: 93934:QSOX2
uniprot id: A0A8C2Y9B1
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

93934:PLRG1
gene id: 93934:PLRG1
uniprot id: A0A8C2SM93
names: Similarity
messages: Belongs to the WD repeat PRL1/PRL2 family.

93934:DHCR7
gene id: 93934:DHCR7
uniprot id: A0A8C2TQF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

93934:LOC107308506
gene id: 93934:LOC107308506
uniprot id: A0A8C2SXN6
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:CCNJ
gene id: 93934:CCNJ
uniprot id: A0A8C2YGH7
names: Similarity
messages: Belongs to the cyclin family.

93934:TNFSF11
gene id: 93934:TNFSF11
uniprot id: A0A8C2UC85
names: Similarity
messages: Belongs to the tumor necrosis factor family.

93934:SMC6
gene id: 93934:SMC6
uniprot id: A0A8C2YAV6
names: Subcellular Location Annotation
messages: Chromosome

93934:SMPD1
gene id: 93934:SMPD1
uniprot id: A0A8C2T0T1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Converts sphingomyelin to ceramide.
messages: Secreted

93934:SCARF2
gene id: 93934:SCARF2
uniprot id: A0A8C2TSC6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:RPS6
gene id: 93934:RPS6
uniprot id: A0A8C2T8Q6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

93934:KIF26B
gene id: 93934:KIF26B
uniprot id: A0A8C2TQ58
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:DHRS7B
gene id: 93934:DHRS7B
uniprot id: A0A8C2SPR6
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:GPLD1
gene id: 93934:GPLD1
uniprot id: A0A8C2YFF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPLD1 family.
messages: Secreted

93934:MYF6
gene id: 93934:MYF6
uniprot id: A0A8C2SML3
names: Subcellular Location Annotation
messages: Nucleus

93934:CREB1
gene id: 93934:CREB1
uniprot id: A0A8C2TUK7
names: Subcellular Location Annotation
messages: Nucleus

93934:DLGAP1
gene id: 93934:DLGAP1
uniprot id: A0A8C2TAH8
names: Similarity
messages: Belongs to the SAPAP family.

93934:PLCG2
gene id: 93934:PLCG2
uniprot id: A0A8C2TSM3
names: Function
messages: Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.

93934:LLPH
gene id: 93934:LLPH
uniprot id: A0A8C2YDW9
names: Similarity
messages: Belongs to the learning-associated protein family.

93934:ETF1
gene id: 93934:ETF1
uniprot id: A0A8C2YB66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

93934:HDGFL2
gene id: 93934:HDGFL2
uniprot id: A0A8C2TDQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HDGF family.
messages: Nucleus

93934:BFSP1
gene id: 93934:BFSP1
uniprot id: A0A8C2TJK5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: cell cortex
messages: cytoskeleton

93934:MTERF3
gene id: 93934:MTERF3
uniprot id: A0A8C2SLD4
names: Similarity
messages: Belongs to the mTERF family.

93934:GADL1
gene id: 93934:GADL1
uniprot id: A0A8C2TL52
names: Similarity
names: Subunit
messages: Belongs to the group II decarboxylase family.
messages: Homodimer.

93934:GFM2
gene id: 93934:GFM2
uniprot id: A0A8C2SQY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

93934:CAPZA2
gene id: 93934:CAPZA2
uniprot id: A0A8C2TJ06
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

93934:SCIN
gene id: 93934:SCIN
uniprot id: A0A8C2THY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the villin/gelsolin family.
messages: cytoskeleton
messages: podosome

93934:FAM172A
gene id: 93934:FAM172A
uniprot id: A0A8C2SLL1
uniprot id: A0A8C2SMG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM172 family.
messages: Cytoplasm
messages: Nucleus

93934:RPP30
gene id: 93934:RPP30
uniprot id: A0A8C2U6F0
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

93934:ANTXR2
gene id: 93934:ANTXR2
uniprot id: A0A8C2TF83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

93934:LOC107314935
gene id: 93934:LOC107314935
uniprot id: A0A8C2U7G7
names: Similarity
messages: Belongs to the aldo/keto reductase family.

93934:PTGS2
gene id: 93934:PTGS2
uniprot id: A0A8C2UEW0
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the prostaglandin G/H synthase family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Endoplasmic reticulum membrane
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Microsome membrane

93934:EIF3B
gene id: 93934:EIF3B
uniprot id: A0A8C2TQX5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

93934:WDR24
gene id: 93934:WDR24
uniprot id: A0A8C2U370
names: Similarity
messages: Belongs to the WD repeat WDR24 family.

93934:EVX2
gene id: 93934:EVX2
uniprot id: A0A8C2U454
names: Subcellular Location Annotation
messages: Nucleus

93934:NRG1
gene id: 93934:NRG1
uniprot id: A0A8C2TKE7
uniprot id: A0A8C2TNI7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neuregulin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:SNX18
gene id: 93934:SNX18
uniprot id: A0A8C2SRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

93934:SLIT2
gene id: 93934:SLIT2
uniprot id: A0A8C2U418
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:SYNGR3
gene id: 93934:SYNGR3
uniprot id: A0A8C2Y7E6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptogyrin family.
messages: Membrane

93934:SAT1
gene id: 93934:SAT1
uniprot id: A0A8C2U5B3
names: Similarity
names: Subunit
messages: Belongs to the acetyltransferase family.
messages: Homodimer.

93934:AHCYL2
gene id: 93934:AHCYL2
uniprot id: A0A8C2SL95
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.

93934:TMEM41A
gene id: 93934:TMEM41A
uniprot id: A0A8C2U7E2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

93934:PRKAR1B
gene id: 93934:PRKAR1B
uniprot id: A0A8C2TR45
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cAMP-dependent kinase regulatory chain family.
messages: Cell membrane
messages: Membrane

93934:LOC107314868
gene id: 93934:LOC107314868
uniprot id: A0A8C2TTB5
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

93934:ANKS1B
gene id: 93934:ANKS1B
uniprot id: A0A8C2T3N4
names: Subcellular Location Annotation
messages: Cytoplasm

93934:MRPL15
gene id: 93934:MRPL15
uniprot id: A0A8C2YAF2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

93934:ESF1
gene id: 93934:ESF1
uniprot id: A0A8C2TLT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

93934:MAL
gene id: 93934:MAL
uniprot id: A0A8C2SX03
names: Subcellular Location Annotation
messages: Membrane

93934:SERPIND1
gene id: 93934:SERPIND1
uniprot id: A0A8C2U8A1
names: Similarity
messages: Belongs to the serpin family.

93934:TEKT1
gene id: 93934:TEKT1
uniprot id: A0A8C2UCB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

93934:ANTXR1
gene id: 93934:ANTXR1
uniprot id: A0A8C2TM42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATR family.
messages: Membrane

93934:ACTR3
gene id: 93934:ACTR3
uniprot id: A0A8C2UDQ3
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

93934:LOC107325684
gene id: 93934:LOC107325684
uniprot id: A0A8C2YA79
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. SYK/ZAP-70 subfamily.

93934:CHST3
gene id: 93934:CHST3
uniprot id: A0A8C2T239
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

93934:KCNQ3
gene id: 93934:KCNQ3
uniprot id: A0A8C2T6Z2
uniprot id: A0A8C2TCA3
uniprot id: A0A8C2Y927
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:PROX1
gene id: 93934:PROX1
uniprot id: A0A8C2T6C5
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107324272
gene id: 93934:LOC107324272
uniprot id: A0A8C2TP67
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

93934:CCN1
gene id: 93934:CCN1
uniprot id: A0A8C2T763
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:DHH
gene id: 93934:DHH
uniprot id: A0A8C2SMK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the hedgehog family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Multimer.
messages: The C-terminal part of the hedgehog protein precursor displays an autoproteolysis activity that results in the cleavage of the full-length protein into two parts (N-product and C-product). In addition, the C-terminal part displays a cholesterol transferase activity that results by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated N-product.
messages: The dually lipidated hedgehog protein N-product is a morphogen which is essential for a variety of patterning events during development.

93934:ATIC
gene id: 93934:ATIC
uniprot id: A0A8C2TU60
names: Similarity
messages: Belongs to the PurH family.

93934:SEC24A
gene id: 93934:SEC24A
uniprot id: A0A8C2SZH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

93934:GATA6
gene id: 93934:GATA6
uniprot id: A0A8C2TFE2
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107310193
gene id: 93934:LOC107310193
uniprot id: A0A8C2YAF4
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:TBCA
gene id: 93934:TBCA
uniprot id: A0A8C2TBB5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: Tubulin-folding protein; involved in the early step of the tubulin folding pathway.
messages: cytoskeleton

93934:TMCC1
gene id: 93934:TMCC1
uniprot id: A0A8C2UIB2
names: Similarity
messages: Belongs to the TEX28 family.

93934:CRKL
gene id: 93934:CRKL
uniprot id: A0A8C2TEB4
names: Similarity
messages: Belongs to the CRK family.

93934:ATP2C2
gene id: 93934:ATP2C2
uniprot id: A0A8C2TUR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:TWF2
gene id: 93934:TWF2
uniprot id: A0A8C2TGJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

93934:METTL14
gene id: 93934:METTL14
uniprot id: A0A8C2SWG6
names: Similarity
messages: Belongs to the MT-A70-like family.

93934:MRPS31
gene id: 93934:MRPS31
uniprot id: A0A8C2U9J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS31 family.
messages: Mitochondrion

93934:SEMA3C
gene id: 93934:SEMA3C
uniprot id: A0A8C2SXF8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:LOC107309690
gene id: 93934:LOC107309690
uniprot id: A0A8C2U0E0
names: Similarity
messages: Belongs to the TMEM14 family.

93934:ODC1
gene id: 93934:ODC1
uniprot id: A0A8C2TFN6
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

93934:LOC107324579
gene id: 93934:LOC107324579
uniprot id: A0A8C2TWT0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the selenium-binding protein family.
messages: Catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria. Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
messages: Membrane
messages: Nucleus
messages: cytosol

93934:TECRL
gene id: 93934:TECRL
uniprot id: A0A8C2YAP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

93934:LOC107325170
gene id: 93934:LOC107325170
uniprot id: A0A8C2U6H5
names: Subcellular Location Annotation
messages: Membrane
messages: chromaffin granule membrane

93934:SMARCA5
gene id: 93934:SMARCA5
uniprot id: A0A8C2ST95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

93934:LIX1
gene id: 93934:LIX1
uniprot id: A0A8C2TLT2
names: Similarity
messages: Belongs to the LIX1 family.

93934:ACSS3
gene id: 93934:ACSS3
uniprot id: A0A8C2SQJ1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:CRYAB
gene id: 93934:CRYAB
uniprot id: A0A8C2TS40
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93934:MIEF1
gene id: 93934:MIEF1
uniprot id: A0A8C2TMU1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion outer membrane

93934:ASTE1
gene id: 93934:ASTE1
uniprot id: A0A8C2SNA6
names: Similarity
messages: Belongs to the asteroid family.

93934:GFM1
gene id: 93934:GFM1
uniprot id: A0A8C2U8Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis.
messages: Mitochondrion

93934:VPS29
gene id: 93934:VPS29
uniprot id: A0A8C2UEQ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
messages: Belongs to the VPS29 family.
messages: Endosome membrane

93934:RBPJ
gene id: 93934:RBPJ
uniprot id: A0A8C2U5U0
uniprot id: A0A8C2U7Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Su(H) family.
messages: Nucleus

93934:TOE1
gene id: 93934:TOE1
uniprot id: A0A8C2THE8
names: Similarity
messages: Belongs to the CAF1 family.

93934:TRNT1
gene id: 93934:TRNT1
uniprot id: A0A8C2U6Z2
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

93934:FMC1
gene id: 93934:FMC1
uniprot id: A0A8C2TEF4
names: Similarity
messages: Belongs to the FMC1 family.

93934:CHRNG
gene id: 93934:CHRNG
uniprot id: A0A8C2TRT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:C15H12orf49
gene id: 93934:C15H12orf49
uniprot id: A0A8C2TVL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPRING family.
messages: Golgi apparatus membrane
messages: Membrane

93934:RBM48
gene id: 93934:RBM48
uniprot id: A0A8C2TBM2
names: Similarity
messages: Belongs to the RBM48 family.

93934:CRH
gene id: 93934:CRH
uniprot id: A0A8C2THM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Secreted

93934:USP10
gene id: 93934:USP10
uniprot id: A0A8C2TWM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C19 family. USP10 subfamily.
messages: Cytoplasm
messages: Nucleus

93934:RAP2B
gene id: 93934:RAP2B
uniprot id: A0A8C2U5J3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

93934:PLK3
gene id: 93934:PLK3
uniprot id: A0A8C2TEM4
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

93934:LSM12
gene id: 93934:LSM12
uniprot id: A0A8C2YGD6
names: Similarity
messages: Belongs to the LSM12 family.

93934:KCNK2
gene id: 93934:KCNK2
uniprot id: A0A8C2T4J7
uniprot id: A0A8C2T541
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:STMN2
gene id: 93934:STMN2
uniprot id: A0A8C2TL82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the stathmin family.
messages: Cytoplasm
messages: Membrane
messages: lamellipodium

93934:SFXN1
gene id: 93934:SFXN1
uniprot id: A0A8C2Y9E8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

93934:NCBP1
gene id: 93934:NCBP1
uniprot id: A0A8C2STM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

93934:ZC2HC1C
gene id: 93934:ZC2HC1C
uniprot id: A0A8C2YGA8
names: Similarity
messages: Belongs to the ZC2HC1 family.

93934:CNTN1
gene id: 93934:CNTN1
uniprot id: A0A8C2TQF9
names: Similarity
messages: Belongs to the immunoglobulin superfamily. Contactin family.

93934:EGFR
gene id: 93934:EGFR
uniprot id: A0A8C2SLP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. EGF receptor subfamily.
messages: Membrane

93934:DOK6
gene id: 93934:DOK6
uniprot id: A0A8C2T800
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

93934:EXTL3
gene id: 93934:EXTL3
uniprot id: A0A8C2TQC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

93934:RAB3IP
gene id: 93934:RAB3IP
uniprot id: A0A8C2TWT5
names: Similarity
messages: Belongs to the SEC2 family.

93934:SESN2
gene id: 93934:SESN2
uniprot id: A0A8C2YE50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

93934:PFKFB3
gene id: 93934:PFKFB3
uniprot id: A0A8C2SZ17
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

93934:KLC1
gene id: 93934:KLC1
uniprot id: A0A8C2SSL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kinesin light chain family.
messages: Kinesin is a microtubule-associated force-producing protein that play a role in organelle transport.
messages: Oligomeric complex composed of two heavy chains and two light chains.
messages: cytoskeleton

93934:PRKCQ
gene id: 93934:PRKCQ
uniprot id: A0A8C2SZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

93934:NNT
gene id: 93934:NNT
uniprot id: A0A8C2TFS2
names: Similarity
messages: In the N-terminal section; belongs to the AlaDH/PNT family.

93934:P4HB
gene id: 93934:P4HB
uniprot id: A0A8C2UJD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

93934:MRPS9
gene id: 93934:MRPS9
uniprot id: A0A8C2TMD3
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

93934:RHO
gene id: 93934:RHO
uniprot id: A0A8C2YHF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
messages: Membrane

93934:SLC26A7
gene id: 93934:SLC26A7
uniprot id: A0A8C2SQ24
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

93934:CENPO
gene id: 93934:CENPO
uniprot id: A0A8C2TQ56
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

93934:ARL6
gene id: 93934:ARL6
uniprot id: A0A8C2SQZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: cilium membrane

93934:OGFR
gene id: 93934:OGFR
uniprot id: A0A8C2SRU0
uniprot id: A0A8C2SUW2
names: Similarity
messages: Belongs to the opioid growth factor receptor family.

93934:FKTN
gene id: 93934:FKTN
uniprot id: A0A8C2TPF4
names: Similarity
messages: Belongs to the LicD transferase family.

93934:MC2R
gene id: 93934:MC2R
uniprot id: A0A8C2T6V7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MRAP; increasing ligand-sensitivity and generation of cAMP. Interacts with MRAP2; competing with MRAP for binding to MC2R and impairing the binding of corticotropin (ACTH).
messages: Membrane

93934:LOC107305757
gene id: 93934:LOC107305757
uniprot id: A0A8C2T3L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNF-like-inhibitor family.
messages: Secreted

93934:MYO1H
gene id: 93934:MYO1H
uniprot id: A0A8C2T885
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:CCND2
gene id: 93934:CCND2
uniprot id: A0A8C2TWV9
uniprot id: A0A8C2U281
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin D subfamily.
messages: Cytoplasm
messages: Nucleus

93934:ARSI
gene id: 93934:ARSI
uniprot id: A0A8C2T1M1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:TLX1
gene id: 93934:TLX1
uniprot id: A0A8C2UBM2
names: Subcellular Location Annotation
messages: Nucleus

93934:CD93
gene id: 93934:CD93
uniprot id: A0A8C2TYD8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:DLG1
gene id: 93934:DLG1
uniprot id: A0A8C2TND4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAGUK family.
messages: Membrane

93934:CALHM1
gene id: 93934:CALHM1
uniprot id: A0A8C2UC22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CALHM family.
messages: Membrane

93934:XPO7
gene id: 93934:XPO7
uniprot id: A0A8C2YDK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

93934:CHRNA2
gene id: 93934:CHRNA2
uniprot id: A0A8C2TQ28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:TRPC6
gene id: 93934:TRPC6
uniprot id: A0A8C2STN9
names: Subcellular Location Annotation
messages: Membrane

93934:WDR18
gene id: 93934:WDR18
uniprot id: A0A8C2YAG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Dynein axonemal particle
messages: nucleolus
messages: nucleoplasm

93934:LOC107307139
gene id: 93934:LOC107307139
uniprot id: A0A8C2SM62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 23 family.
messages: Secreted

93934:SYNE3
gene id: 93934:SYNE3
uniprot id: A0A8C2SQJ4
names: Similarity
messages: Belongs to the nesprin family.

93934:EGF
gene id: 93934:EGF
uniprot id: A0A8C2T4N2
uniprot id: A0A8C2T5W6
names: Caution
names: Function
names: Subunit
messages: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
messages: Interacts with EGFR and promotes EGFR dimerization.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:G6PC3
gene id: 93934:G6PC3
uniprot id: A0A8C2YGC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

93934:GRIK1
gene id: 93934:GRIK1
uniprot id: A0A8C2SZY8
uniprot id: A0A8C2SZZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:SMO
gene id: 93934:SMO
uniprot id: A0A8C2SNJ9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LOC107308460
gene id: 93934:LOC107308460
uniprot id: A0A8C2SWR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Membrane

93934:SEC61A1
gene id: 93934:SEC61A1
uniprot id: A0A8C2TSA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:SMIM5
gene id: 93934:SMIM5
uniprot id: A0A8C2UCK8
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107321671
gene id: 93934:LOC107321671
uniprot id: A0A8C2TZ43
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:SSTR3
gene id: 93934:SSTR3
uniprot id: A0A8C2TSA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:PLCD4
gene id: 93934:PLCD4
uniprot id: A0A8C2TQF7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Nucleus

93934:VWC2L
gene id: 93934:VWC2L
uniprot id: A0A8C2TQG3
names: Subcellular Location Annotation
messages: Synapse

93934:PANX1
gene id: 93934:PANX1
uniprot id: A0A8C2SUB1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: S-nitrosylation inhibits channel currents and ATP release.
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

93934:LOC107310358
gene id: 93934:LOC107310358
uniprot id: A0A8C2SLJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

93934:STX12
gene id: 93934:STX12
uniprot id: A0A8C2YDR8
names: Similarity
messages: Belongs to the syntaxin family.

93934:SPG7
gene id: 93934:SPG7
uniprot id: A0A8C2TUA7
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

93934:DLX3
gene id: 93934:DLX3
uniprot id: A0A8C2UB17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the distal-less homeobox family.
messages: Nucleus

93934:RPL3L
gene id: 93934:RPL3L
uniprot id: A0A8C2SZJ9
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

93934:CBLB
gene id: 93934:CBLB
uniprot id: A0A8C2U562
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.
messages: The N-terminus is composed of the phosphotyrosine binding (PTB) domain, a short linker region and the RING-type zinc finger. The PTB domain, which is also called TKB (tyrosine kinase binding) domain, is composed of three different subdomains: a four-helix bundle (4H), a calcium-binding EF hand and a divergent SH2 domain.

93934:LOC107319873
gene id: 93934:LOC107319873
uniprot id: A0A8C2U1D9
names: Function
names: Similarity
messages: Belongs to the apovitellenin family.
messages: Protein component of the very low density lipoprotein (VLDL) of egg-laying females. Potent lipoprotein lipase inhibitor, preventing the loss of triglycerides from VLDL on their way from the liver to the growing oocytes.

93934:LOC107312398
gene id: 93934:LOC107312398
uniprot id: A0A8C2YC47
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:CTNNAL1
gene id: 93934:CTNNAL1
uniprot id: A0A8C2T2S2
names: Similarity
messages: Belongs to the vinculin/alpha-catenin family.

93934:CDK9
gene id: 93934:CDK9
uniprot id: A0A8C2YGS0
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:SIAH2
gene id: 93934:SIAH2
uniprot id: A0A8C2U779
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

93934:GRPEL1
gene id: 93934:GRPEL1
uniprot id: A0A8C2YFS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

93934:ARL1
gene id: 93934:ARL1
uniprot id: A0A8C2Y8P8
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

93934:SLC10A7
gene id: 93934:SLC10A7
uniprot id: A0A8C2SPI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
messages: Cell membrane
messages: Does not show transport activity towards bile acids or steroid sulfates.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

93934:LIPT2
gene id: 93934:LIPT2
uniprot id: A0A8C2T361
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Mitochondrion

93934:BCDIN3D
gene id: 93934:BCDIN3D
uniprot id: A0A8C2STI2
names: Similarity
messages: Belongs to the methyltransferase superfamily.

93934:FGB
gene id: 93934:FGB
uniprot id: A0A8C2SKU0
names: Subcellular Location Annotation
names: Subunit
messages: Heterohexamer; disulfide linked. Contains 2 sets of 3 non-identical chains (alpha, beta and gamma). The 2 heterotrimers are in head to head conformation with the N-termini in a small central domain.
messages: Secreted

93934:SFRP4
gene id: 93934:SFRP4
uniprot id: A0A8C2TTG4
names: Caution
names: Similarity
messages: Belongs to the secreted frizzled-related protein (sFRP) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SEPTIN4
gene id: 93934:SEPTIN4
uniprot id: A0A8C2T0E8
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.

93934:LTBP2
gene id: 93934:LTBP2
uniprot id: A0A8C2YGA6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:SYNM
gene id: 93934:SYNM
uniprot id: A0A8C2UEC9
names: Similarity
messages: Belongs to the intermediate filament family.

93934:SLCO3A1
gene id: 93934:SLCO3A1
uniprot id: A0A8C2UD63
uniprot id: A0A8C2UES4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:BBS7
gene id: 93934:BBS7
uniprot id: A0A8C2SW33
names: Function
names: Subunit
messages: Part of BBSome complex.
messages: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function.

93934:TBPL1
gene id: 93934:TBPL1
uniprot id: A0A8C2TBU0
names: Similarity
messages: Belongs to the TBP family.

93934:ADAMTS1
gene id: 93934:ADAMTS1
uniprot id: A0A8C2SWI4
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:SRPRA
gene id: 93934:SRPRA
uniprot id: A0A8C2T2P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

93934:NUP210
gene id: 93934:NUP210
uniprot id: A0A8C2TRF1
names: Similarity
messages: Belongs to the NUP210 family.

93934:LOC107314286
gene id: 93934:LOC107314286
uniprot id: A0A8C2TRR7
names: Similarity
messages: Belongs to the CD225/Dispanin family.

93934:VCL
gene id: 93934:VCL
uniprot id: A0A8C2TJJ9
uniprot id: A0A8C2TJL3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.
messages: Belongs to the vinculin/alpha-catenin family.
messages: Cell membrane
messages: Membrane
messages: adherens junction

93934:PHB
gene id: 93934:PHB
uniprot id: A0A8C2YGC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Cell membrane
messages: Mitochondrion inner membrane

93934:TSPO2
gene id: 93934:TSPO2
uniprot id: A0A8C2U650
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TspO/BZRP family.
messages: Membrane

93934:HOXD8
gene id: 93934:HOXD8
uniprot id: A0A8C2U5V1
names: Subcellular Location Annotation
messages: Nucleus

93934:FZR1
gene id: 93934:FZR1
uniprot id: A0A8C2T0M7
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

93934:ZIC1
gene id: 93934:ZIC1
uniprot id: A0A8C2TNP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

93934:TMEM41B
gene id: 93934:TMEM41B
uniprot id: A0A8C2SW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM41 family.
messages: Membrane

93934:TTYH3
gene id: 93934:TTYH3
uniprot id: A0A8C2TU17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tweety family.
messages: Cell membrane
messages: Membrane
messages: Probable chloride channel.

93934:ATG2B
gene id: 93934:ATG2B
uniprot id: A0A8C2SQP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Lipid droplet
messages: Preautophagosomal structure membrane

93934:ASPN
gene id: 93934:ASPN
uniprot id: A0A8C2TMN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: extracellular matrix

93934:LOC107305821
gene id: 93934:LOC107305821
uniprot id: A0A8C2T3K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the APH-1 family.
messages: Component of the gamma-secretase complex.
messages: Membrane
messages: Potential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors.

93934:GCNT3
gene id: 93934:GCNT3
uniprot id: A0A8C2TPD0
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

93934:LOC107324760
gene id: 93934:LOC107324760
uniprot id: A0A8C2TCC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase.

93934:ITM2A
gene id: 93934:ITM2A
uniprot id: A0A8C2ST81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITM2 family.
messages: Membrane

93934:GET4
gene id: 93934:GET4
uniprot id: A0A8C2TTQ8
names: Similarity
messages: Belongs to the GET4 family.

93934:RACK1
gene id: 93934:RACK1
uniprot id: A0A8C2TXU7
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

93934:LIAS
gene id: 93934:LIAS
uniprot id: A0A8C2YFB4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

93934:LOC107310746
gene id: 93934:LOC107310746
uniprot id: A0A8C2TWR8
names: Similarity
messages: Belongs to the TMEM121 family.

93934:TSPAN12
gene id: 93934:TSPAN12
uniprot id: A0A8C2TMB9
uniprot id: A0A8C2TMR0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:GTPBP1
gene id: 93934:GTPBP1
uniprot id: A0A8C2TQA5
names: Function
messages: Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity.

93934:AASDHPPT
gene id: 93934:AASDHPPT
uniprot id: A0A8C2SST4
names: Similarity
messages: Belongs to the P-Pant transferase superfamily. AcpS family.

93934:GNS
gene id: 93934:GNS
uniprot id: A0A8C2TXQ2
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Lysosome
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:USP5
gene id: 93934:USP5
uniprot id: A0A8C2TZ41
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:CD9
gene id: 93934:CD9
uniprot id: A0A8C2TZR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Cell membrane
messages: Membrane
messages: extracellular exosome

93934:C7H2orf88
gene id: 93934:C7H2orf88
uniprot id: A0A8C2TQ15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small membrane AKAP family.
messages: Cell membrane
messages: Membrane

93934:DOK2
gene id: 93934:DOK2
uniprot id: A0A8C2TWX6
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

93934:STON2
gene id: 93934:STON2
uniprot id: A0A8C2UB71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating.
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: synaptosome

93934:NPM1
gene id: 93934:NPM1
uniprot id: A0A8C2TGT3
names: Similarity
messages: Belongs to the nucleoplasmin family.

93934:VNN1
gene id: 93934:VNN1
uniprot id: A0A8C2TBU9
names: Similarity
messages: Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.

93934:MAN2A1
gene id: 93934:MAN2A1
uniprot id: A0A8C2TBD5
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

93934:RBM47
gene id: 93934:RBM47
uniprot id: A0A8C2U4Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM RBM47 family.
messages: Nucleus

93934:CPA6
gene id: 93934:CPA6
uniprot id: A0A8C2TKZ3
names: Similarity
messages: Belongs to the peptidase M14 family.

93934:STAT4
gene id: 93934:STAT4
uniprot id: A0A8C2TCN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcription factor STAT family.
messages: Cytoplasm
messages: Nucleus

93934:CAMK1D
gene id: 93934:CAMK1D
uniprot id: A0A8C2SVU9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:ELOVL7
gene id: 93934:ELOVL7
uniprot id: A0A8C2SSX7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family. ELOVL7 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. May participate to the production of saturated and polyunsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LMF2
gene id: 93934:LMF2
uniprot id: A0A8C2SMA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lipase maturation factor family.
messages: Endoplasmic reticulum membrane
messages: Involved in the maturation of specific proteins in the endoplasmic reticulum.
messages: Membrane

93934:FOXQ1
gene id: 93934:FOXQ1
uniprot id: A0A8C2TXQ4
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107319305
gene id: 93934:LOC107319305
uniprot id: A0A8C2TRJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the C19orf12 family.
messages: Mitochondrion membrane

93934:RAD21
gene id: 93934:RAD21
uniprot id: A0A8C2Y7F9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

93934:GAB1
gene id: 93934:GAB1
uniprot id: A0A8C2SRD9
uniprot id: A0A8C2Y5M4
names: Similarity
messages: Belongs to the GAB family.

93934:LOC107314870
gene id: 93934:LOC107314870
uniprot id: A0A8C2TW92
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

93934:SLC35A1
gene id: 93934:SLC35A1
uniprot id: A0A8C2SV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35A subfamily.
messages: Membrane

93934:SLC25A38
gene id: 93934:SLC25A38
uniprot id: A0A8C2SWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis.
messages: Mitochondrion inner membrane

93934:TAGLN
gene id: 93934:TAGLN
uniprot id: A0A8C2TGP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calponin family.
messages: Cytoplasm

93934:TMEM18
gene id: 93934:TMEM18
uniprot id: A0A8C2T709
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM18 family.
messages: Membrane
messages: Nucleus membrane

93934:TP63
gene id: 93934:TP63
uniprot id: A0A8C2TP53
uniprot id: A0A8C2TS41
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
messages: Belongs to the p53 family.
messages: Binds 1 zinc ion per subunit.
messages: Binds DNA as a homotetramer. Isoform composition of the tetramer may determine transactivation activity.
messages: Nucleus

93934:NRN1
gene id: 93934:NRN1
uniprot id: A0A8C2U321
names: Similarity
messages: Belongs to the neuritin family.

93934:PLAGL2
gene id: 93934:PLAGL2
uniprot id: A0A8C2SYR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

93934:SESN3
gene id: 93934:SESN3
uniprot id: A0A8C2SUA2
uniprot id: A0A8C2SWZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sestrin family.
messages: Cytoplasm

93934:HSPA5
gene id: 93934:HSPA5
uniprot id: A0A8C2TIW4
uniprot id: A0ZT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heat shock protein 70 family.
messages: Endoplasmic reticulum lumen

93934:RAPGEF2
gene id: 93934:RAPGEF2
uniprot id: A0A8C2SLK0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAPGEF2 family.
messages: Cell junction
messages: Endosome
messages: Late endosome
messages: perinuclear region

93934:SSU72
gene id: 93934:SSU72
uniprot id: A0A8C2TD04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSU72 phosphatase family.
messages: Nucleus
messages: Protein phosphatase that catalyzes the dephosphorylation of the C-terminal domain of RNA polymerase II. Plays a role in RNA processing and termination.

93934:IGF2BP1
gene id: 93934:IGF2BP1
uniprot id: A0A8C2U7M7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM IMP/VICKZ family.
messages: Nucleus
messages: filopodium
messages: growth cone
messages: lamellipodium
messages: perinuclear region

93934:CREM
gene id: 93934:CREM
uniprot id: A0A8C2SSC9
names: Subcellular Location Annotation
messages: Nucleus

93934:SCUBE2
gene id: 93934:SCUBE2
uniprot id: A0A8C2SWR4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:PIWIL1
gene id: 93934:PIWIL1
uniprot id: A0A8C2UAS6
names: Similarity
messages: Belongs to the argonaute family.

93934:NR6A1
gene id: 93934:NR6A1
uniprot id: A0A8C2YAV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:CLUL1
gene id: 93934:CLUL1
uniprot id: A0A8C2TBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clusterin family.
messages: Secreted

93934:INTU
gene id: 93934:INTU
uniprot id: A0A8C2T093
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inturned family.
messages: Cell surface
messages: cilium basal body

93934:SLC15A5
gene id: 93934:SLC15A5
uniprot id: A0A8C2Y625
names: Similarity
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.

93934:FAM160B1
gene id: 93934:FAM160B1
uniprot id: A0A8C2YGV8
names: Similarity
messages: Belongs to the FHIP family.

93934:SLC13A5
gene id: 93934:SLC13A5
uniprot id: A0A8C2UBZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily.
messages: Membrane

93934:LOC107317966
gene id: 93934:LOC107317966
uniprot id: A0A8C2Y7M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

93934:RPL7L1
gene id: 93934:RPL7L1
uniprot id: A0A8C2STJ1
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

93934:CSPG4
gene id: 93934:CSPG4
uniprot id: A0A8C2T6C2
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SMAD7
gene id: 93934:SMAD7
uniprot id: A0A8C2SX14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:ELAC2
gene id: 93934:ELAC2
uniprot id: A0A8C2UAQ9
names: Similarity
messages: Belongs to the RNase Z family.

93934:HAAO
gene id: 93934:HAAO
uniprot id: A0A8C2TAJ6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93934:RPUSD2
gene id: 93934:RPUSD2
uniprot id: A0A8C2TSC1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

93934:TMEM135
gene id: 93934:TMEM135
uniprot id: A0A8C2SV49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM135 family.
messages: Membrane
messages: Peroxisome membrane

93934:STAM
gene id: 93934:STAM
uniprot id: A0A8C2Y7H8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Early endosome membrane

93934:MAP3K15
gene id: 93934:MAP3K15
uniprot id: A0A8C2U2P3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

93934:BCL7A
gene id: 93934:BCL7A
uniprot id: A0A8C2UEM7
names: Similarity
messages: Belongs to the BCL7 family.

93934:TBC1D7
gene id: 93934:TBC1D7
uniprot id: A0A8C2U4X4
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Vesicle

93934:NDUFB8
gene id: 93934:NDUFB8
uniprot id: A0A8C2U9Q9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB8 subunit family.
messages: Complex I is composed of 45 different subunits.
messages: Mitochondrion inner membrane

93934:ACAP2
gene id: 93934:ACAP2
uniprot id: A0A8C2TJU0
uniprot id: A0A8C2TQ14
names: Activity Regulation
names: Domain
names: Function
names: Subcellular Location Annotation
messages: Endosome membrane
messages: GAP activity stimulated by phosphatidylinositol 4,5-bisphosphate (PIP2) and phosphatidic acid.
messages: GTPase-activating protein for the ADP ribosylation factor family.
messages: PH domain binds phospholipids including phosphatidic acid, phosphatidylinositol 3-phosphate, phosphatidylinositol 3,5-bisphosphate (PIP2) and phosphatidylinositol 3,4,5-trisphosphate (PIP3). May mediate protein binding to PIP2 or PIP3 containing membranes.
messages: The BAR domain mediates homodimerization, it can neither bind membrane nor impart curvature, but instead requires the neighboring PH domain to achieve these functions.

93934:ARHGDIA
gene id: 93934:ARHGDIA
uniprot id: A0A8C2UDQ0
names: Similarity
messages: Belongs to the Rho GDI family.

93934:PAQR3
gene id: 93934:PAQR3
uniprot id: A0A8C2THH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

93934:THBS1
gene id: 93934:THBS1
uniprot id: A0A8C2TZT9
names: Caution
names: Similarity
messages: Belongs to the thrombospondin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:AP2A2
gene id: 93934:AP2A2
uniprot id: A0A8C2U4U1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type subunit AP2A1 or AP2A2 and beta-type subunit AP2B1), a medium adaptin (mu-type subunit AP2M1) and a small adaptin (sigma-type subunit AP2S1).
messages: Belongs to the adaptor complexes large subunit family.
messages: Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif.
messages: coated pit

93934:UGCG
gene id: 93934:UGCG
uniprot id: A0A8C2SNZ5
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

93934:RND3
gene id: 93934:RND3
uniprot id: A0A8C2UFQ4
names: Function
messages: Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins.

93934:NF2
gene id: 93934:NF2
uniprot id: A0A8C2TUU9
uniprot id: A0A8C2TYD4
names: Subcellular Location Annotation
messages: Membrane
messages: cytoskeleton

93934:KCNB1
gene id: 93934:KCNB1
uniprot id: A0A8C2SSN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.1/KCNB1 sub-subfamily.
messages: Lateral cell membrane
messages: Membrane
messages: Perikaryon
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane
messages: axon
messages: sarcolemma
messages: synaptosome

93934:ADD3
gene id: 93934:ADD3
uniprot id: A0A8C2U9U0
uniprot id: A0A8C2UC23
names: Similarity
messages: Belongs to the aldolase class II family. Adducin subfamily.

93934:NEUROD6
gene id: 93934:NEUROD6
uniprot id: A0A8C2T328
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

93934:NXPH2
gene id: 93934:NXPH2
uniprot id: A0A8C2UDW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

93934:LOC107312394
gene id: 93934:LOC107312394
uniprot id: A0A8C2Y977
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:BNIP1
gene id: 93934:BNIP1
uniprot id: A0A8C2TCF8
names: Subcellular Location Annotation
messages: Membrane

93934:ARAP2
gene id: 93934:ARAP2
uniprot id: A0A8C2U495
uniprot id: A0A8C2U8Z9
names: Subcellular Location Annotation
messages: Cytoplasm

93934:TIPIN
gene id: 93934:TIPIN
uniprot id: A0A8C2UFQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSM3 family.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

93934:VWC2
gene id: 93934:VWC2
uniprot id: A0A8C2TXY2
names: Subcellular Location Annotation
messages: Synapse

93934:SLC22A4
gene id: 93934:SLC22A4
uniprot id: A0A8C2YHJ3
names: Similarity
names: Subunit
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
messages: Interacts with PDZK1.

93934:GLOD4
gene id: 93934:GLOD4
uniprot id: A0A8C2U1D8
names: Similarity
messages: Belongs to the glyoxalase I family.

93934:ENTPD2
gene id: 93934:ENTPD2
uniprot id: A0A8C2TW12
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:STARD5
gene id: 93934:STARD5
uniprot id: A0A8C2YH12
names: Function
messages: May be involved in the intracellular transport of sterols or other lipids. May bind cholesterol or other sterols.

93934:LOC107313521
gene id: 93934:LOC107313521
uniprot id: A0A8C2SQU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1 family.
messages: Membrane

93934:ZDHHC23
gene id: 93934:ZDHHC23
uniprot id: A0A8C2U6F8
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:TACC3
gene id: 93934:TACC3
uniprot id: A0A8C2SXU7
uniprot id: A0A8C2Y749
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACC family.
messages: Cytoplasm

93934:SEC31B
gene id: 93934:SEC31B
uniprot id: A0A8C2U5K4
uniprot id: A0A8C2U5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: Endoplasmic reticulum membrane

93934:HMX1
gene id: 93934:HMX1
uniprot id: A0A8C2UA71
names: Subcellular Location Annotation
messages: Nucleus

93934:GALNT9
gene id: 93934:GALNT9
uniprot id: A0A8C2UAR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:HACD1
gene id: 93934:HACD1
uniprot id: A0A8C2SYG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:GK
gene id: 93934:GK
uniprot id: A0A8C2U1N2
uniprot id: A0A8C2U2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FGGY kinase family.
messages: Cytoplasm

93934:DPH5
gene id: 93934:DPH5
uniprot id: A0A8C2UH74
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

93934:BBS4
gene id: 93934:BBS4
uniprot id: A0A8C2Y8K2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBS4 family.
messages: Membrane
messages: centrosome
messages: cilium membrane

93934:C18H17orf80
gene id: 93934:C18H17orf80
uniprot id: A0A8C2UIL7
names: Function
names: Similarity
messages: Belongs to the ATPase F chain family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.

93934:GABPA
gene id: 93934:GABPA
uniprot id: A0A8C2SWE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:PTCH1
gene id: 93934:PTCH1
uniprot id: A0A8C2TB27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the patched family.
messages: Membrane

93934:NMUR2
gene id: 93934:NMUR2
uniprot id: A0A8C2T5Q5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

93934:REEP3
gene id: 93934:REEP3
uniprot id: A0A8C2TX58
uniprot id: A0A8C2TZD1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Membrane

93934:ITPK1
gene id: 93934:ITPK1
uniprot id: A0A8C2SNQ9
names: Similarity
messages: Belongs to the ITPK1 family.

93934:PRPF18
gene id: 93934:PRPF18
uniprot id: A0A8C2SY75
uniprot id: A0A8C2SZQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP18 family.
messages: Nucleus speckle

93934:MID1
gene id: 93934:MID1
uniprot id: A0A8C2U3V6
names: Function
names: Subcellular Location Annotation
messages: Has E3 ubiquitin ligase activity towards IGBP1, promoting its monoubiquitination, which results in deprotection of the catalytic subunit of protein phosphatase PP2A, and its subsequent degradation by polyubiquitination.
messages: cytoskeleton

93934:PTGES
gene id: 93934:PTGES
uniprot id: A0A8C2UGQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Membrane

93934:CNR1
gene id: 93934:CNR1
uniprot id: A0A8C2SWU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: G-protein coupled receptor for cannabinoids. Mediates many cannabinoid-induced effects in the central nervous system (CNS), as well as in peripheral tissues. Signaling typically involves reduction in cyclic AMP.
messages: Membrane
messages: Mitochondrion outer membrane
messages: Presynapse
messages: Synapse
messages: axon

93934:LGALS3
gene id: 93934:LGALS3
uniprot id: A0A8C2T222
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus
messages: Secreted

93934:PEX13
gene id: 93934:PEX13
uniprot id: A0A8C2TXK7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

93934:RSL24D1
gene id: 93934:RSL24D1
uniprot id: A0A8C2U1Q0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

93934:MBP
gene id: 93934:MBP
uniprot id: A0A8C2T5D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin basic protein family.
messages: Myelin membrane

93934:KIN
gene id: 93934:KIN
uniprot id: A0A8C2Y6T6
names: Similarity
messages: Belongs to the KIN17 family.

93934:CLUH
gene id: 93934:CLUH
uniprot id: A0A8C2UAF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLU family.
messages: Cytoplasm
messages: Cytoplasmic granule
messages: mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis.

93934:SIAH3
gene id: 93934:SIAH3
uniprot id: A0A8C2YGM2
names: Domain
names: Function
names: Similarity
messages: Belongs to the SINA (Seven in absentia) family.
messages: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.
messages: The RING-type zinc finger domain is essential for ubiquitin ligase activity.
messages: The SBD domain (substrate-binding domain) mediates the interaction with substrate proteins. It is related to the TRAF family.

93934:PPP1R9B
gene id: 93934:PPP1R9B
uniprot id: A0A8C2U752
names: Subcellular Location Annotation
messages: cytoskeleton

93934:CHRNA4
gene id: 93934:CHRNA4
uniprot id: A0A8C2Y5X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:PRRC1
gene id: 93934:PRRC1
uniprot id: A0A8C2TP85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRRC1 family.
messages: Golgi apparatus

93934:SUPT3H
gene id: 93934:SUPT3H
uniprot id: A0A8C2ST43
names: Subcellular Location Annotation
messages: Nucleus

93934:NLGN3
gene id: 93934:NLGN3
uniprot id: A0A8C2TK56
uniprot id: A0A8C2TKB1
uniprot id: A0A8C2TNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

93934:RPL34
gene id: 93934:RPL34
uniprot id: A0A8C2YA11
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

93934:DUSP5
gene id: 93934:DUSP5
uniprot id: A0A8C2UFB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

93934:SLC6A15
gene id: 93934:SLC6A15
uniprot id: A0A8C2SX22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A15 subfamily.
messages: Membrane

93934:RAP2C
gene id: 93934:RAP2C
uniprot id: A0A8C2U026
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ras family.
messages: Endosome membrane
messages: Recycling endosome membrane

93934:HSPD1
gene id: 93934:HSPD1
uniprot id: A0A8C2SV56
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

93934:SH3GL3
gene id: 93934:SH3GL3
uniprot id: A0A8C2UG68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

93934:IMP4
gene id: 93934:IMP4
uniprot id: A0A8C2Y4V4
names: Subcellular Location Annotation
messages: nucleolus

93934:WNT7A
gene id: 93934:WNT7A
uniprot id: A0A8C2TM20
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:BCAS2
gene id: 93934:BCAS2
uniprot id: A0A8C2U3C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPF27 family.
messages: Nucleus

93934:AJAP1
gene id: 93934:AJAP1
uniprot id: A0A8C2TAL3
uniprot id: A0A8C2TE11
names: Subcellular Location Annotation
messages: Membrane

93934:PARK7
gene id: 93934:PARK7
uniprot id: A0A8C2T3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C56 family.
messages: Membrane raft

93934:ARL4C
gene id: 93934:ARL4C
uniprot id: A0A8C2TQB2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

93934:KLHL3
gene id: 93934:KLHL3
uniprot id: A0A8C2T295
names: Subcellular Location Annotation
messages: cytoskeleton
messages: cytosol

93934:IREB2
gene id: 93934:IREB2
uniprot id: A0A8C2T8K9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Cytoplasm
messages: RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.

93934:MRE11
gene id: 93934:MRE11
uniprot id: A0A8C2Y6E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

93934:SLC12A1
gene id: 93934:SLC12A1
uniprot id: A0A8C2YGN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Cell membrane
messages: Membrane

93934:TBX15
gene id: 93934:TBX15
uniprot id: A0A8C2U1P3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:CRELD2
gene id: 93934:CRELD2
uniprot id: A0A8C2T7X2
names: Caution
names: Similarity
messages: Belongs to the CRELD family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107312758
gene id: 93934:LOC107312758
uniprot id: A0A8C2U1X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

93934:ABL1
gene id: 93934:ABL1
uniprot id: A0A8C2Y5I8
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:GPRIN2
gene id: 93934:GPRIN2
uniprot id: A0A8C2TKD0
names: Function
messages: May be involved in neurite outgrowth.

93934:THOC5
gene id: 93934:THOC5
uniprot id: A0A8C2TW17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC5 family.
messages: Nucleus

93934:MTRF1
gene id: 93934:MTRF1
uniprot id: A0A8C2UAN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prokaryotic/mitochondrial release factor family.
messages: Mitochondrion

93934:TOB2
gene id: 93934:TOB2
uniprot id: A0A8C2Y9R6
names: Similarity
messages: Belongs to the BTG family.

93934:B4GALT1
gene id: 93934:B4GALT1
uniprot id: A0A8C2Y690
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

93934:ABHD3
gene id: 93934:ABHD3
uniprot id: A0A8C2Y9V1
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

93934:CAMLG
gene id: 93934:CAMLG
uniprot id: A0A8C2T218
names: Function
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

93934:SEC61B
gene id: 93934:SEC61B
uniprot id: A0A8C2T323
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

93934:CDK1
gene id: 93934:CDK1
uniprot id: A0A8C2TWE7
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:CAB39
gene id: 93934:CAB39
uniprot id: A0A8C2SZG8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mo25 family.
messages: Component of a complex that binds and activates STK11/LKB1. In the complex, required to stabilize the interaction between CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta) and STK11/LKB1.
messages: Component of a trimeric complex composed of STK11/LKB1, STRAD (STRADA or STRADB) and CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta): the complex tethers STK11/LKB1 in the cytoplasm and stimulates its catalytic activity.

93934:MSANTD3
gene id: 93934:MSANTD3
uniprot id: A0A8C2Y8A5
names: Similarity
messages: Belongs to the MSANTD3 family.

93934:RPS6KA1
gene id: 93934:RPS6KA1
uniprot id: A0A8C2TUB7
uniprot id: A0A8C2TZP5
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

93934:MPPE1
gene id: 93934:MPPE1
uniprot id: A0A8C2T6L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallophosphoesterase superfamily. MPPE1 family.
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Membrane
messages: Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
messages: cis-Golgi network membrane

93934:NPR3
gene id: 93934:NPR3
uniprot id: A0A8C2T3H3
names: Subcellular Location Annotation
messages: Membrane

93934:D2HGDH
gene id: 93934:D2HGDH
uniprot id: A0A8C2Y5B5
names: Similarity
messages: Belongs to the FAD-binding oxidoreductase/transferase type 4 family.

93934:PEX10
gene id: 93934:PEX10
uniprot id: A0A8C2TAR0
names: Function
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.
messages: Somewhat implicated in the biogenesis of peroxisomes.

93934:CCKAR
gene id: 93934:CCKAR
uniprot id: A0A8C2U7K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

93934:PRKAB2
gene id: 93934:PRKAB2
uniprot id: A0A8C2UIR6
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

93934:MED28
gene id: 93934:MED28
uniprot id: A0A8C2U7P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 28 family.
messages: Nucleus

93934:TMPRSS7
gene id: 93934:TMPRSS7
uniprot id: A0A8C2U6P0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LOC107318689
gene id: 93934:LOC107318689
uniprot id: A0A8C2U732
names: Subcellular Location Annotation
messages: cytoskeleton

93934:TRPC4
gene id: 93934:TRPC4
uniprot id: A0A8C2UBA0
names: Subcellular Location Annotation
messages: Membrane

93934:HMGCLL1
gene id: 93934:HMGCLL1
uniprot id: A0A8C2TAS8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HMG-CoA lyase family.
messages: Homodimer; disulfide-linked. Can also form homotetramers.
messages: Mitochondrial 3-hydroxymethyl-3-methylglutaryl-CoA lyase that catalyzes a cation-dependent cleavage of (S)-3-hydroxy-3-methylglutaryl-CoA into acetyl-CoA and acetoacetate, a key step in ketogenesis. Terminal step in leucine catabolism. Ketone bodies (beta-hydroxybutyrate, acetoacetate and acetone) are essential as an alternative source of energy to glucose, as lipid precursors and as regulators of metabolism.

93934:GNA11
gene id: 93934:GNA11
uniprot id: A0A8C2TFG2
names: Similarity
messages: Belongs to the G-alpha family. G(q) subfamily.

93934:LOC107306504
gene id: 93934:LOC107306504
uniprot id: A0A8C2SQ58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM161 family.
messages: Membrane

93934:STK40
gene id: 93934:STK40
uniprot id: A0A8C2YEU1
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: May be a negative regulator of NF-kappa-B and p53-mediated gene transcription.
messages: Nucleus

93934:GREM2
gene id: 93934:GREM2
uniprot id: A0A8C2TSX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DAN family.
messages: Secreted

93934:TMEM201
gene id: 93934:TMEM201
uniprot id: A0A8C2TGZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM201 family.
messages: Membrane
messages: Nucleus inner membrane

93934:FMNL2
gene id: 93934:FMNL2
uniprot id: A0A8C2UC80
uniprot id: A0A8C2UDN8
uniprot id: A0A8C2YH85
names: Similarity
messages: Belongs to the formin homology family.

93934:BZW1
gene id: 93934:BZW1
uniprot id: A0A8C2TYM6
names: Similarity
messages: Belongs to the BZW family.

93934:LYN
gene id: 93934:LYN
uniprot id: A0A8C2TGN3
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:PIGW
gene id: 93934:PIGW
uniprot id: A0A8C2U214
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

93934:CUL4B
gene id: 93934:CUL4B
uniprot id: A0A8C2U606
names: Similarity
messages: Belongs to the cullin family.

93934:NRDE2
gene id: 93934:NRDE2
uniprot id: A0A8C2SNK9
names: Similarity
messages: Belongs to the NRDE2 family.

93934:HSPA13
gene id: 93934:HSPA13
uniprot id: A0A8C2SXI7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93934:RPA1
gene id: 93934:RPA1
uniprot id: A0A8C2TJT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: PML body

93934:PPP1R3B
gene id: 93934:PPP1R3B
uniprot id: A0A8C2TIH2
names: Subunit
messages: Interacts with glycogen, PPP1CC catalytic subunit of PP1 and PYGL. Associates with glycogen particles. Forms complexes with debranching enzyme, glycogen phosphorylase, glycogen synthase and phosphorylase kinase which is necessary for its regulation of PP1 activity.

93934:OPRD1
gene id: 93934:OPRD1
uniprot id: A0A8C2YE72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:GJC2
gene id: 93934:GJC2
uniprot id: A0A8C2TE23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:KDM1B
gene id: 93934:KDM1B
uniprot id: A0A8C2U680
names: Similarity
messages: Belongs to the flavin monoamine oxidase family.

93934:FAM3C
gene id: 93934:FAM3C
uniprot id: A0A8C2TA67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM3 family.
messages: Secreted

93934:FXR1
gene id: 93934:FXR1
uniprot id: A0A8C2TU82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMR1 family.
messages: Cytoplasm

93934:UNCX
gene id: 93934:UNCX
uniprot id: A0A8C2TQS9
names: Subcellular Location Annotation
messages: Nucleus

93934:AK2
gene id: 93934:AK2
uniprot id: A0A8C2SNJ6
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.

93934:ABCC1
gene id: 93934:ABCC1
uniprot id: A0A8C2YDM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Cell membrane
messages: Membrane

93934:EXTL1
gene id: 93934:EXTL1
uniprot id: A0A8C2TZS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

93934:IBSP
gene id: 93934:IBSP
uniprot id: A0A8C2YA56
names: Function
names: Subcellular Location Annotation
messages: Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
messages: Secreted

93934:MRPL22
gene id: 93934:MRPL22
uniprot id: A0A8C2Y8K3
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

93934:PPIP5K1
gene id: 93934:PPIP5K1
uniprot id: A0A8C2SL89
uniprot id: A0A8C2SMM8
uniprot id: A0A8C2SNK1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histidine acid phosphatase family. VIP1 subfamily.
messages: Bifunctional inositol kinase that acts in concert with the IP6K kinases to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, may regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, and exocytosis. Phosphorylates inositol hexakisphosphate (InsP6).
messages: cytosol

93934:RPS11
gene id: 93934:RPS11
uniprot id: A0A8C2T263
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

93934:HOXA3
gene id: 93934:HOXA3
uniprot id: A0A8C2TK04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:AR
gene id: 93934:AR
uniprot id: A0A8C2SUL4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Nucleus

93934:TMEM132D
gene id: 93934:TMEM132D
uniprot id: A0A8C2YGL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM132 family.
messages: Membrane

93934:FER
gene id: 93934:FER
uniprot id: A0A8C2TBG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
messages: cytoskeleton

93934:THNSL2
gene id: 93934:THNSL2
uniprot id: A0A8C2T249
names: Similarity
messages: Belongs to the threonine synthase family.

93934:PDGFRA
gene id: 93934:PDGFRA
uniprot id: A0A8C2TGC0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Cell membrane
messages: Interacts with homodimeric PDGFA, PDGFB and PDGFC, and with heterodimers formed by PDGFA and PDGFB. Monomer in the absence of bound ligand.
messages: Membrane
messages: Present in an inactive conformation in the absence of bound ligand. Binding of PDGFA and/or PDGFB leads to dimerization and activation by autophosphorylation on tyrosine residues.
messages: Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.

93934:C10H15orf40
gene id: 93934:C10H15orf40
uniprot id: A0A8C2UG58
names: Similarity
messages: Belongs to the UPF0235 family.

93934:LETM1
gene id: 93934:LETM1
uniprot id: A0A8C2SNV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LETM1 family.
messages: Membrane
messages: Mitochondrion inner membrane

93934:WASF2
gene id: 93934:WASF2
uniprot id: A0A8C2TWP1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SCAR/WAVE family.
messages: Binds actin and the Arp2/3 complex.
messages: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex.
messages: cytoskeleton

93934:PGK1
gene id: 93934:PGK1
uniprot id: A0A8C2U1C1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

93934:IL6
gene id: 93934:IL6
uniprot id: A0A8C2TM19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

93934:LMOD1
gene id: 93934:LMOD1
uniprot id: A0A8C2TD53
names: Subcellular Location Annotation
messages: cytoskeleton
messages: sarcomere

93934:SMYD2
gene id: 93934:SMYD2
uniprot id: A0A8C2T7W8
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'.
messages: cytosol

93934:NUS1
gene id: 93934:NUS1
uniprot id: A0A8C2TF55
names: Similarity
messages: Belongs to the UPP synthase family.

93934:RAE1
gene id: 93934:RAE1
uniprot id: A0A8C2T8T3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat rae1 family.
messages: spindle pole

93934:CPOX
gene id: 93934:CPOX
uniprot id: A0A8C2U1I5
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

93934:KCNAB1
gene id: 93934:KCNAB1
uniprot id: A0A8C2U386
uniprot id: A0A8C2U3J8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shaker potassium channel beta subunit family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

93934:LOC107318593
gene id: 93934:LOC107318593
uniprot id: Q8QFN5
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZP domain family. ZPC subfamily.
messages: Cell membrane
messages: Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP3 is essential for sperm binding and zona matrix formation.
messages: Membrane
messages: Proteolytically cleaved before the transmembrane segment to yield the secreted ectodomain incorporated in the zona pellucida.
messages: The ZP domain is involved in the polymerization of the ZP proteins to form the zona pellucida.
messages: Zona pellucida

93934:YIPF5
gene id: 93934:YIPF5
uniprot id: A0A8C2UFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

93934:LOC107312630
gene id: 93934:LOC107312630
uniprot id: A0A8C2T9A9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:LOC107323276
gene id: 93934:LOC107323276
uniprot id: A0A8C2TD15
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:LOC107312130
gene id: 93934:LOC107312130
uniprot id: A0A8C2T9S6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

93934:PGM1
gene id: 93934:PGM1
uniprot id: A0A8C2TRZ7
uniprot id: A0A8C2TS15
names: Similarity
messages: Belongs to the phosphohexose mutase family.

93934:METTL15
gene id: 93934:METTL15
uniprot id: A0A8C2TYK6
names: Similarity
messages: Belongs to the methyltransferase superfamily. RsmH family.

93934:RPTOR
gene id: 93934:RPTOR
uniprot id: A0A8C2UHI8
names: Similarity
messages: Belongs to the WD repeat RAPTOR family.

93934:NRXN3
gene id: 93934:NRXN3
uniprot id: A0A8C2U778
uniprot id: A0A8C2U9P4
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:CTBS
gene id: 93934:CTBS
uniprot id: A0A8C2T7V4
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

93934:RGS3
gene id: 93934:RGS3
uniprot id: A0A8C2YE18
names: Subcellular Location Annotation
messages: Cytoplasm

93934:GPR137B
gene id: 93934:GPR137B
uniprot id: A0A8C2UD38
names: Subcellular Location Annotation
messages: Lysosome membrane
messages: Membrane

93934:IRF2BP2
gene id: 93934:IRF2BP2
uniprot id: A0A8C2SU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IRF2BP family.
messages: Nucleus

93934:TRIM2
gene id: 93934:TRIM2
uniprot id: A0A8C2Y4Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRIM/RBCC family.
messages: Cytoplasm

93934:SCNN1A
gene id: 93934:SCNN1A
uniprot id: A0A8C2U068
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107321830
gene id: 93934:LOC107321830
uniprot id: A0A8C2UBK4
names: Similarity
messages: Belongs to the ClpA/ClpB family. Torsin subfamily.

93934:SGIP1
gene id: 93934:SGIP1
uniprot id: A0A8C2TV47
names: Subcellular Location Annotation
messages: clathrin-coated pit

93934:ATXN3
gene id: 93934:ATXN3
uniprot id: A0A8C2SSK9
names: Subcellular Location Annotation
messages: Nucleus

93934:ZNF326
gene id: 93934:ZNF326
uniprot id: A0A8C2Y917
names: Similarity
messages: Belongs to the AKAP95 family.

93934:EAF2
gene id: 93934:EAF2
uniprot id: A0A8C2UFM9
names: Similarity
messages: Belongs to the EAF family.

93934:ATP5MC3
gene id: 93934:ATP5MC3
uniprot id: A0A8C2U6W9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element.
messages: Mitochondrion membrane

93934:MEF2C
gene id: 93934:MEF2C
uniprot id: A0A8C2SL03
uniprot id: A0A8C2SL09
names: Subcellular Location Annotation
messages: Nucleus

93934:GCAT
gene id: 93934:GCAT
uniprot id: A0A8C2TNQ1
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

93934:SLC5A11
gene id: 93934:SLC5A11
uniprot id: A0A8C2TD09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:NPY2R
gene id: 93934:NPY2R
uniprot id: A0A8C2SKZ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:CCT5
gene id: 93934:CCT5
uniprot id: A0A8C2TT67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

93934:ARHGAP26
gene id: 93934:ARHGAP26
uniprot id: A0A8C2UCY1
uniprot id: A0A8C2YHH4
names: Subcellular Location Annotation
messages: cytoskeleton
messages: focal adhesion

93934:ZNF503
gene id: 93934:ZNF503
uniprot id: A0A8C2THS2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Elbow/Noc family.
messages: Nucleus

93934:KCNK1
gene id: 93934:KCNK1
uniprot id: A0A8C2SSW5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Cell membrane
messages: Cytoplasmic vesicle
messages: Endosome
messages: Membrane
messages: Perikaryon
messages: Recycling endosome
messages: Synaptic cell membrane
messages: Vesicle
messages: dendrite

93934:ALK
gene id: 93934:ALK
uniprot id: A0A8C2SR61
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.

93934:SSTR4
gene id: 93934:SSTR4
uniprot id: A0A8C2TWQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:NDUFB5
gene id: 93934:NDUFB5
uniprot id: A0A8C2TRR8
names: Function
names: Similarity
names: Subunit
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB5 subunit family.
messages: Complex I is composed of 45 different subunits.

93934:MAN2C1
gene id: 93934:MAN2C1
uniprot id: A0A8C2T5E7
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

93934:GTPBP8
gene id: 93934:GTPBP8
uniprot id: A0A8C2U3D9
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.

93934:SOSTDC1
gene id: 93934:SOSTDC1
uniprot id: A0A8C2TN34
names: Caution
names: Similarity
messages: Belongs to the sclerostin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:HEXIM1
gene id: 93934:HEXIM1
uniprot id: A0A8C2U6T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HEXIM family.
messages: Nucleus

93934:OGDHL
gene id: 93934:OGDHL
uniprot id: A0A8C2TP13
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

93934:C2H18orf21
gene id: 93934:C2H18orf21
uniprot id: A0A8C2TXU4
names: Similarity
messages: Belongs to the UPF0711 family.

93934:SUGCT
gene id: 93934:SUGCT
uniprot id: A0A8C2T0T2
names: Similarity
messages: Belongs to the CoA-transferase III family.

93934:DPY19L4
gene id: 93934:DPY19L4
uniprot id: A0A8C2SNU0
uniprot id: A0A8C2Y4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dpy-19 family.
messages: Membrane
messages: Probable C-mannosyltransferase that mediates C-mannosylation of tryptophan residues on target proteins.

93934:PRNP
gene id: 93934:PRNP
uniprot id: A0A8C2TM58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prion family.
messages: Cell membrane
messages: Membrane

93934:ABITRAM
gene id: 93934:ABITRAM
uniprot id: A0A8C2T3P8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABITRAM family.
messages: growth cone
messages: lamellipodium

93934:SLC25A6
gene id: 93934:SLC25A6
uniprot id: A0A8C2YFM3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

93934:SFXN2
gene id: 93934:SFXN2
uniprot id: A0A8C2UC01
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

93934:MCM9
gene id: 93934:MCM9
uniprot id: A0A8C2T9P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCM family.
messages: Nucleus

93934:RFX3
gene id: 93934:RFX3
uniprot id: A0A8C2STK5
uniprot id: A0A8C2SV60
names: Subcellular Location Annotation
messages: Nucleus

93934:CX3CR1
gene id: 93934:CX3CR1
uniprot id: A0A8C2SX40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Early endosome
messages: Endosome
messages: Membrane

93934:NEK9
gene id: 93934:NEK9
uniprot id: A0A8C2U9C1
uniprot id: A0A8C2YGB8
names: Similarity
messages: Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.

93934:MMP15
gene id: 93934:MMP15
uniprot id: A0A8C2TJ11
names: Similarity
messages: Belongs to the peptidase M10A family.

93934:OSBPL10
gene id: 93934:OSBPL10
uniprot id: A0A8C2TR71
names: Similarity
messages: Belongs to the OSBP family.

93934:LOC107321021
gene id: 93934:LOC107321021
uniprot id: A0A8C2U815
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:CPB1
gene id: 93934:CPB1
uniprot id: A0A8C2TJZ2
uniprot id: A0A8C2TMN6
names: Similarity
messages: Belongs to the peptidase M14 family.

93934:LOC107325032
gene id: 93934:LOC107325032
uniprot id: A0A8C2YG50
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:SOD1
gene id: 93934:SOD1
uniprot id: A0A8C2T159
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

93934:ATP6V0C
gene id: 93934:ATP6V0C
uniprot id: A0A8C2U477
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and the accessory subunits.
messages: Vacuole membrane
messages: clathrin-coated vesicle membrane
messages: synaptic vesicle membrane

93934:PDGFRB
gene id: 93934:PDGFRB
uniprot id: A0A8C2T1B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
messages: Membrane

93934:HNF4A
gene id: 93934:HNF4A
uniprot id: A0A8C2SPU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:ACVRL1
gene id: 93934:ACVRL1
uniprot id: A0A8C2U7W7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:SUCLG1
gene id: 93934:SUCLG1
uniprot id: A0A8C2T2L2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit. Different beta subunits determine nucleotide specificity. Together with the ATP-specific beta subunit SUCLA2, forms an ADP-forming succinyl-CoA synthetase (A-SCS). Together with the GTP-specific beta subunit SUCLG2 forms a GDP-forming succinyl-CoA synthetase (G-SCS).
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits.

93934:SLC7A9
gene id: 93934:SLC7A9
uniprot id: A0A8C2YD30
names: Subcellular Location Annotation
messages: Membrane

93934:EXT2
gene id: 93934:EXT2
uniprot id: A0A8C2YAU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 47 family.
messages: Endoplasmic reticulum membrane

93934:RGS7BP
gene id: 93934:RGS7BP
uniprot id: A0A8C2SQB2
names: Similarity
messages: Belongs to the RGS7BP/RGS9BP family.

93934:ATP7A
gene id: 93934:ATP7A
uniprot id: A0A8C2U3B5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane
messages: trans-Golgi network membrane

93934:TCF7
gene id: 93934:TCF7
uniprot id: A0A8C2SXK7
uniprot id: A0A8C2SY47
uniprot id: A0A8C2T0N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCF/LEF family.
messages: Nucleus

93934:FAM98A
gene id: 93934:FAM98A
uniprot id: A0A8C2TK41
names: Similarity
messages: Belongs to the FAM98 family.

93934:HACD4
gene id: 93934:HACD4
uniprot id: A0A8C2T519
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107314092
gene id: 93934:LOC107314092
uniprot id: A0A8C2T4P4
names: Similarity
messages: Belongs to the vasopressin/oxytocin family.

93934:APOD
gene id: 93934:APOD
uniprot id: A0A8C2YBR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Secreted

93934:SUPV3L1
gene id: 93934:SUPV3L1
uniprot id: A0A8C2Y630
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family.
messages: mitochondrion nucleoid

93934:CAV3
gene id: 93934:CAV3
uniprot id: A0A8C2UG69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola
messages: sarcolemma

93934:LRRC8D
gene id: 93934:LRRC8D
uniprot id: A0A8C2Y983
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

93934:LRRC8A
gene id: 93934:LRRC8A
uniprot id: A0A8C2UG80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

93934:LOC107317562
gene id: 93934:LOC107317562
uniprot id: A0A8C2T9D0
names: Similarity
messages: Belongs to the CLCR family.

93934:SH3GL1
gene id: 93934:SH3GL1
uniprot id: A0A8C2TDE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Membrane

93934:ATP2A3
gene id: 93934:ATP2A3
uniprot id: A0A8C2TAI9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

93934:PDK4
gene id: 93934:PDK4
uniprot id: A0A8C2TH31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

93934:SH3RF2
gene id: 93934:SH3RF2
uniprot id: A0A8C2UDM1
names: Similarity
messages: Belongs to the SH3RF family.

93934:IAPP
gene id: 93934:IAPP
uniprot id: A0A8C2SUI9
names: Similarity
messages: Belongs to the calcitonin family.

93934:RAG1
gene id: 93934:RAG1
uniprot id: A0A8C2YAN5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAG1 family.
messages: Binds 1 divalent metal cation per subunit. Mg(2+) or Mn(2+).
messages: Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break between the RSS and the adjacent coding segment. RAG2 is not a catalytic component but is required for all known catalytic activities. DNA cleavage occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the phosphodiester bond on the opposite strand in a direct transesterification reaction, thereby creating 4 DNA ends: 2 hairpin coding ends and 2 blunt, 5'-phosphorylated ends.
messages: Homodimer.
messages: Nucleus
messages: The NBD (nonamer binding) DNA-binding domain mediates the specific binding to the nonamer RSS motif by forming a tightly interwoven homodimer that binds and synapses 2 nonamer elements, with each NBD making contact with both DNA molecules. Each RSS is composed of well-conserved heptamer (consensus 5'-CACAGTG-3') and nonamer (consensus 5'-ACAAAAACC-3') sequences separated by a spacer of either 12 bp or 23 bp.

93934:PMM2
gene id: 93934:PMM2
uniprot id: A0A8C2TYV7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

93934:DCN
gene id: 93934:DCN
uniprot id: Q9DE68
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
messages: Binds to type I and type II collagen, to fibronectin and TGF-beta. Forms a ternary complex with MFAP2 and ELN (By similarity).
messages: May affect the rate of fibrils formation.
messages: The attached glycosaminoglycan chain can be either chondroitin sulfate or dermatan sulfate depending upon the tissue of origin.
messages: extracellular matrix

93934:BCL9
gene id: 93934:BCL9
uniprot id: A0A8C2STT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCL9 family.
messages: Nucleus

93934:GALNT17
gene id: 93934:GALNT17
uniprot id: A0A8C2SW80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:CC2D1B
gene id: 93934:CC2D1B
uniprot id: A0A8C2YBD7
names: Similarity
messages: Belongs to the CC2D1 family.

93934:LOC107322729
gene id: 93934:LOC107322729
uniprot id: A0A8C2TF10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

93934:B3GAT2
gene id: 93934:B3GAT2
uniprot id: A0A8C2T431
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 43 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:LOC107322176
gene id: 93934:LOC107322176
uniprot id: A0A8C2UBQ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYBC1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ZNF706
gene id: 93934:ZNF706
uniprot id: A0A8C2SNE8
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:ARHGDIG
gene id: 93934:ARHGDIG
uniprot id: A0A8C2YEE0
names: Similarity
messages: Belongs to the Rho GDI family.

93934:LOC107317608
gene id: 93934:LOC107317608
uniprot id: A0A8C2TGD3
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

93934:IKBKB
gene id: 93934:IKBKB
uniprot id: A0A8C2TUU2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:GFRA1
gene id: 93934:GFRA1
uniprot id: A0A8C2UC40
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: 2 molecules of GDNFR-alpha are thought to form a complex with the disulfide-linked GDNF dimer and with 2 molecules of RET.
messages: Belongs to the GDNFR family.
messages: Cell membrane
messages: Membrane
messages: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor.

93934:ZMPSTE24
gene id: 93934:ZMPSTE24
uniprot id: A0A8C2TYN1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

93934:LOC107315945
gene id: 93934:LOC107315945
uniprot id: A0A8C2UA09
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:CDC6
gene id: 93934:CDC6
uniprot id: A0A8C2ST23
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC6/cdc18 family.
messages: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.
messages: Nucleus

93934:FBXO34
gene id: 93934:FBXO34
uniprot id: A0A8C2T1F1
names: Function
messages: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

93934:PLA1A
gene id: 93934:PLA1A
uniprot id: A0A8C2U177
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. Lipase family.
messages: Secreted

93934:SATB2
gene id: 93934:SATB2
uniprot id: A0A8C2TUM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CUT homeobox family.
messages: Nucleus

93934:DCLK2
gene id: 93934:DCLK2
uniprot id: A0A8C2SPY2
uniprot id: A0A8C2SSH2
uniprot id: A0A8C2Y5H5
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily.

93934:PHYHIPL
gene id: 93934:PHYHIPL
uniprot id: A0A8C2YBN0
names: Similarity
messages: Belongs to the PHYHIP family.

93934:STN1
gene id: 93934:STN1
uniprot id: A0A8C2UDA9
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the CST complex proposed to act as a specialized replication factor promoting DNA replication under conditions of replication stress or natural replication barriers such as the telomere duplex. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. Initially the CST complex has been proposed to protect telomeres from DNA degradation. However, the CST complex has been shown to be involved in several aspects of telomere replication.
messages: Component of the CST complex.
messages: Nucleus
messages: telomere

93934:DUSP6
gene id: 93934:DUSP6
uniprot id: A0A8C2Y767
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

93934:C7H2orf76
gene id: 93934:C7H2orf76
uniprot id: A0A8C2UE00
names: Similarity
messages: Belongs to the UPF0538 family.

93934:PPTC7
gene id: 93934:PPTC7
uniprot id: A0A8C2UEF0
names: Similarity
messages: Belongs to the PP2C family.

93934:INO80
gene id: 93934:INO80
uniprot id: A0A8C2TWF0
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

93934:TFRC
gene id: 93934:TFRC
uniprot id: A0A8C2YCM4
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Cell membrane
messages: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Acts as a lipid sensor that regulates mitochondrial fusion by regulating activation of the JNK pathway.
messages: Homodimer; disulfide-linked.
messages: Melanosome
messages: Membrane
messages: Stearoylated.

93934:ATP11B
gene id: 93934:ATP11B
uniprot id: A0A8C2TT64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:NSUN3
gene id: 93934:NSUN3
uniprot id: A0A8C2YF70
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

93934:MTMR2
gene id: 93934:MTMR2
uniprot id: A0A8C2SU12
uniprot id: A0A8C2SX39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

93934:NEDD9
gene id: 93934:NEDD9
uniprot id: A0A8C2U297
uniprot id: A0A8C2U2K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAS family.
messages: focal adhesion

93934:CCR4
gene id: 93934:CCR4
uniprot id: A0A8C2SVW6
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:LOC107310073
gene id: 93934:LOC107310073
uniprot id: A0A8C2TC08
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:SLC25A16
gene id: 93934:SLC25A16
uniprot id: A0A8C2SU39
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:LOC107313061
gene id: 93934:LOC107313061
uniprot id: A0A8C2SL00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
messages: Membrane

93934:ALDH4A1
gene id: 93934:ALDH4A1
uniprot id: A0A8C2YFB5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93934:MTIF3
gene id: 93934:MTIF3
uniprot id: A0A8C2UGV5
names: Similarity
messages: Belongs to the IF-3 family.

93934:TMEM9B
gene id: 93934:TMEM9B
uniprot id: A0A8C2SWB6
names: Similarity
messages: Belongs to the TMEM9 family.

93934:SUFU
gene id: 93934:SUFU
uniprot id: A0A8C2UA05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUFU family.
messages: Cytoplasm
messages: Nucleus

93934:GCG
gene id: 93934:GCG
uniprot id: A0A8C2TW59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

93934:DICER1
gene id: 93934:DICER1
uniprot id: A0A8C2SQI4
names: Function
names: Similarity
messages: Belongs to the helicase family. Dicer subfamily.
messages: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

93934:YIPF1
gene id: 93934:YIPF1
uniprot id: A0A8C2YBS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane
messages: cis-Golgi network membrane
messages: trans-Golgi network membrane

93934:MYF5
gene id: 93934:MYF5
uniprot id: A0A8C2Y5B3
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

93934:NIPA2
gene id: 93934:NIPA2
uniprot id: A0A8C2U7U9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

93934:SEPSECS
gene id: 93934:SEPSECS
uniprot id: A0A8C2U404
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SepSecS family.
messages: Converts O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm
messages: Homotetramer formed by a catalytic dimer and a non-catalytic dimer serving as a binding platform that orients tRNASec for catalysis. Each tetramer binds the CCA ends of two tRNAs which point to the active sites of the catalytic dimer.

93934:LOC107308697
gene id: 93934:LOC107308697
uniprot id: A0A8C2YBJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Membrane

93934:ERCC3
gene id: 93934:ERCC3
uniprot id: A0A8C2TLT5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

93934:SCAMP1
gene id: 93934:SCAMP1
uniprot id: A0A8C2Y8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCAMP family.
messages: Membrane

93934:DNASE1L3
gene id: 93934:DNASE1L3
uniprot id: A0A8C2TPX6
names: Similarity
messages: Belongs to the DNase I family.

93934:LIN28B
gene id: 93934:LIN28B
uniprot id: A0A8C2Y9Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lin-28 family.
messages: nucleolus

93934:TSPAN1
gene id: 93934:TSPAN1
uniprot id: A0A8C2TCR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:ABHD2
gene id: 93934:ABHD2
uniprot id: A0A8C2UD44
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

93934:LOC107325286
gene id: 93934:LOC107325286
uniprot id: A0A8C2SW37
names: Similarity
messages: Belongs to the intermediate filament family.

93934:MAK16
gene id: 93934:MAK16
uniprot id: A0A8C2TWA8
names: Similarity
messages: Belongs to the MAK16 family.

93934:LOC107324364
gene id: 93934:LOC107324364
uniprot id: A0A8C2TR65
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:LAPTM5
gene id: 93934:LAPTM5
uniprot id: A0A8C2TXV0
names: Similarity
messages: Belongs to the LAPTM4/LAPTM5 transporter family.

93934:HTRA1
gene id: 93934:HTRA1
uniprot id: A0A8C2UEH7
names: Similarity
messages: Belongs to the peptidase S1C family.

93934:VCAN
gene id: 93934:VCAN
uniprot id: A0A8C2SL60
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:RTRAF
gene id: 93934:RTRAF
uniprot id: A0A8C2TGJ7
names: Similarity
messages: Belongs to the RTRAF family.

93934:SDR42E1
gene id: 93934:SDR42E1
uniprot id: A0A8C2YD88
names: Similarity
messages: Belongs to the 3-beta-HSD family.

93934:CHRDL2
gene id: 93934:CHRDL2
uniprot id: A0A8C2T497
names: Subcellular Location Annotation
messages: Secreted

93934:GCHFR
gene id: 93934:GCHFR
uniprot id: A0A8C2YCK2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GFRP family.
messages: Membrane
messages: Nucleus membrane
messages: cytosol

93934:MDK
gene id: 93934:MDK
uniprot id: A0A8C2TPR5
names: Similarity
messages: Belongs to the pleiotrophin family.

93934:CTPS2
gene id: 93934:CTPS2
uniprot id: A0A8C2U2Y6
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

93934:LOC107321370
gene id: 93934:LOC107321370
uniprot id: A0A8C2TRY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:F2R
gene id: 93934:F2R
uniprot id: A0A8C2SP46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:GPR83
gene id: 93934:GPR83
uniprot id: A0A8C2SU75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:SKOR2
gene id: 93934:SKOR2
uniprot id: A0A8C2SZ13
names: Similarity
messages: Belongs to the SKI family.

93934:GPD1L
gene id: 93934:GPD1L
uniprot id: A0A8C2TQ10
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

93934:ANOS1
gene id: 93934:ANOS1
uniprot id: Q90369
names: Function
names: Subcellular Location Annotation
messages: Cell surface
messages: May be an adhesion-like molecule with anti-protease activity.

93934:KCNB2
gene id: 93934:KCNB2
uniprot id: A0A8C2THM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. B (Shab) (TC 1.A.1.2) subfamily. Kv2.2/KCNB2 sub-subfamily.
messages: Cell membrane
messages: Membrane
messages: Perikaryon

93934:YPEL2
gene id: 93934:YPEL2
uniprot id: A0A8C2U2R0
names: Similarity
messages: Belongs to the yippee family.

93934:GPRC5B
gene id: 93934:GPRC5B
uniprot id: A0A8C2U4D7
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:LOC107324061
gene id: 93934:LOC107324061
uniprot id: A0A8C2TVN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

93934:DDT
gene id: 93934:DDT
uniprot id: A0A8C2T8A7
names: Similarity
messages: Belongs to the MIF family.

93934:CITED4
gene id: 93934:CITED4
uniprot id: A0A8C2YDT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CITED family.
messages: Nucleus

93934:CAVIN4
gene id: 93934:CAVIN4
uniprot id: A0A8C2T820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola
messages: sarcomere

93934:SUSD3
gene id: 93934:SUSD3
uniprot id: A0A8C2TM29
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CCDC107
gene id: 93934:CCDC107
uniprot id: A0A8C2TZ39
names: Similarity
messages: Belongs to the ric-3 family.

93934:SGSM3
gene id: 93934:SGSM3
uniprot id: A0A8C2TE40
names: Similarity
messages: Belongs to the small G protein signaling modulator family.

93934:XRCC6
gene id: 93934:XRCC6
uniprot id: A0A8C2TBY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus

93934:SCML4
gene id: 93934:SCML4
uniprot id: A0A8C2Y9Y6
names: Subcellular Location Annotation
messages: Nucleus

93934:LARS1
gene id: 93934:LARS1
uniprot id: A0A8C2UEW6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:NEMP1
gene id: 93934:NEMP1
uniprot id: A0A8C2SVY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

93934:KCNK10
gene id: 93934:KCNK10
uniprot id: A0A8C2SMM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:CNTNAP5
gene id: 93934:CNTNAP5
uniprot id: A0A8C2TQU8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May play a role in the correct development and proper functioning of the peripheral and central nervous system and be involved in cell adhesion and intercellular communication.
messages: Membrane

93934:CDH11
gene id: 93934:CDH11
uniprot id: A0A8C2YDB4
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:EFTUD2
gene id: 93934:EFTUD2
uniprot id: A0A8C2U6E0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Nucleus

93934:EMC2
gene id: 93934:EMC2
uniprot id: A0A8C2SXM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

93934:LOC107308051
gene id: 93934:LOC107308051
uniprot id: A0A8C2YGJ4
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:DDIT4
gene id: 93934:DDIT4
uniprot id: A0A8C2TE15
names: Similarity
messages: Belongs to the DDIT4 family.

93934:P4HA3
gene id: 93934:P4HA3
uniprot id: A0A8C2T2Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the P4HA family.
messages: Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
messages: Endoplasmic reticulum lumen

93934:CPNE4
gene id: 93934:CPNE4
uniprot id: A0A8C2SNA1
names: Similarity
messages: Belongs to the copine family.

93934:NTS
gene id: 93934:NTS
uniprot id: A0A8C2Y6X5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurotensin family.
messages: Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.
messages: Secreted
messages: Vesicle
messages: secretory vesicle

93934:LOC107318199
gene id: 93934:LOC107318199
uniprot id: A0A8C2TJS1
names: Function
names: Similarity
messages: Belongs to the phospholipid scramblase family.
messages: May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane.

93934:LOC107312866
gene id: 93934:LOC107312866
uniprot id: A0A8C2U0V5
names: Similarity
messages: Belongs to the PrpD family.

93934:HEBP1
gene id: 93934:HEBP1
uniprot id: A0A8C2Y979
names: Similarity
messages: Belongs to the HEBP family.

93934:ST8SIA2
gene id: 93934:ST8SIA2
uniprot id: A0A8C2UDN7
uniprot id: A0A8C2UGL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:HMGA1
gene id: 93934:HMGA1
uniprot id: A0A8C2YFF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGA family.
messages: Nucleus

93934:SLC25A21
gene id: 93934:SLC25A21
uniprot id: A0A8C2U8P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:DERL2
gene id: 93934:DERL2
uniprot id: A0A8C2TCJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome.
messages: Membrane

93934:SLC17A5
gene id: 93934:SLC17A5
uniprot id: A0A8C2T4Y1
uniprot id: A0A8C2Y8F4
names: Subcellular Location Annotation
messages: Membrane

93934:ATG4C
gene id: 93934:ATG4C
uniprot id: A0A8C2TWT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cysteine protease that plays a key role in autophagy by mediating both proteolytic activation and delipidation of ATG8 family proteins.
messages: Cytoplasm

93934:PLAG1
gene id: 93934:PLAG1
uniprot id: A0A8C2TIM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the krueppel C2H2-type zinc-finger protein family.
messages: Nucleus

93934:LOC107309737
gene id: 93934:LOC107309737
uniprot id: A0A8C2U6B7
names: Function
messages: The products of the Gag polyproteins of infectious retroviruses perform highly complex orchestrated tasks during the assembly, budding, maturation, and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. Endogenous Gag proteins may have kept, lost or modified their original function during evolution.

93934:CLCN3
gene id: 93934:CLCN3
uniprot id: A0A8C2SN18
uniprot id: A0A8C2SN52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-3/CLCN3 subfamily.
messages: Cell membrane
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Membrane

93934:MDH1
gene id: 93934:MDH1
uniprot id: A0A8C2TID6
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.

93934:TRPC7
gene id: 93934:TRPC7
uniprot id: A0A8C2T0V6
uniprot id: A0A8C2Y755
names: Subcellular Location Annotation
messages: Membrane

93934:IK
gene id: 93934:IK
uniprot id: A0A8C2TN21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RED family.
messages: Nucleus

93934:POPDC2
gene id: 93934:POPDC2
uniprot id: A0A8C2U683
names: Similarity
messages: Belongs to the popeye family.

93934:ATP6V1A
gene id: 93934:ATP6V1A
uniprot id: A0A8C2YEW4
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.

93934:MBOAT1
gene id: 93934:MBOAT1
uniprot id: A0A8C2YFE1
names: Subcellular Location Annotation
messages: Membrane

93934:ACSS1
gene id: 93934:ACSS1
uniprot id: A0A8C2SUY8
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:ZNF330
gene id: 93934:ZNF330
uniprot id: A0A8C2SNM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOA36 family.
messages: nucleolus

93934:LEPROTL1
gene id: 93934:LEPROTL1
uniprot id: A0A8C2TH46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

93934:LOC107314688
gene id: 93934:LOC107314688
uniprot id: A0A8C2YAN1
names: Similarity
messages: Belongs to the LDH/MDH superfamily. LDH family.

93934:LOC107315535
gene id: 93934:LOC107315535
uniprot id: A0A8C2YB85
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:EIF2S1
gene id: 93934:EIF2S1
uniprot id: A0A8C2U5E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2-alpha family.
messages: Stress granule

93934:FAM32A
gene id: 93934:FAM32A
uniprot id: A0A8C2TXR3
names: Similarity
messages: Belongs to the FAM32 family.

93934:ASPA
gene id: 93934:ASPA
uniprot id: A0A8C2TYG1
names: Cofactor
names: Similarity
messages: Belongs to the AspA/AstE family. Aspartoacylase subfamily.
messages: Binds 1 zinc ion per subunit.

93934:SERPINI1
gene id: 93934:SERPINI1
uniprot id: A0A8C2U6M6
names: Similarity
messages: Belongs to the serpin family.

93934:JUP
gene id: 93934:JUP
uniprot id: A0A8C2SZP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: desmosome

93934:RPN2
gene id: 93934:RPN2
uniprot id: A0A8C2YHH8
uniprot id: A0A8C2YHH9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

93934:AARS2
gene id: 93934:AARS2
uniprot id: A0A8C2TGD8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Alax-L subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Monomer. Interacts with ANKRD16; the interaction is direct.

93934:HPRT1
gene id: 93934:HPRT1
uniprot id: A0A8C2TYM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

93934:FOXF1
gene id: 93934:FOXF1
uniprot id: A0A8C2YDC3
names: Subcellular Location Annotation
messages: Nucleus

93934:DLX6
gene id: 93934:DLX6
uniprot id: A0A8C2TKF2
names: Subcellular Location Annotation
messages: Nucleus

93934:IGHMBP2
gene id: 93934:IGHMBP2
uniprot id: A0A8C2TPG3
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

93934:PODXL2
gene id: 93934:PODXL2
uniprot id: A0A8C2TQA4
names: Subcellular Location Annotation
messages: Membrane

93934:EYA2
gene id: 93934:EYA2
uniprot id: A0A8C2SML5
uniprot id: A0A8C2SMN3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAD-like hydrolase superfamily. EYA family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nucleus

93934:CDC34
gene id: 93934:CDC34
uniprot id: A0A8C2YAI9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:ACVR2B
gene id: 93934:ACVR2B
uniprot id: A0A8C2TIX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:NDUFS1
gene id: 93934:NDUFS1
uniprot id: A0A8C2TWY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I 75 kDa subunit family.
messages: Mitochondrion inner membrane

93934:IRX2
gene id: 93934:IRX2
uniprot id: A0A8C2TWV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TALE/IRO homeobox family.
messages: Nucleus

93934:DPH6
gene id: 93934:DPH6
uniprot id: A0A8C2U1J1
names: Similarity
messages: Belongs to the Diphthine--ammonia ligase family.

93934:SCFD2
gene id: 93934:SCFD2
uniprot id: A0A8C2THG4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

93934:ASPM
gene id: 93934:ASPM
uniprot id: A0A8C2UDM0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:TNS1
gene id: 93934:TNS1
uniprot id: A0A8C2TPG5
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

93934:SLC39A6
gene id: 93934:SLC39A6
uniprot id: A0A8C2T369
names: Subcellular Location Annotation
messages: Membrane

93934:PRDM15
gene id: 93934:PRDM15
uniprot id: A0A8C2TBX0
names: Subcellular Location Annotation
messages: Nucleus

93934:STXBP5
gene id: 93934:STXBP5
uniprot id: A0A8C2SZW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

93934:FTSJ3
gene id: 93934:FTSJ3
uniprot id: A0A8C2YG84
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Interacts with NIP7.
messages: Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation.
messages: nucleolus

93934:STXBP5L
gene id: 93934:STXBP5L
uniprot id: A0A8C2U0X0
uniprot id: A0A8C2U5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat L(2)GL family.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

93934:EVC2
gene id: 93934:EVC2
uniprot id: A0A8C2U4X9
names: Subcellular Location Annotation
messages: Membrane
messages: cilium basal body
messages: cilium membrane

93934:NR2F2
gene id: 93934:NR2F2
uniprot id: A0A8C2UEL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:IPMK
gene id: 93934:IPMK
uniprot id: A0A8C2TLW1
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

93934:NSF
gene id: 93934:NSF
uniprot id: A0A8C2U887
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

93934:G6PC2
gene id: 93934:G6PC2
uniprot id: A0A8C2UCR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucose-6-phosphatase family.
messages: Endoplasmic reticulum membrane

93934:SLC2A12
gene id: 93934:SLC2A12
uniprot id: A0A8C2T943
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

93934:UHRF2
gene id: 93934:UHRF2
uniprot id: A0A8C2SVE9
names: Subcellular Location Annotation
messages: Nucleus

93934:GDF1
gene id: 93934:GDF1
uniprot id: A0A8C2TIW0
names: Similarity
messages: Belongs to the TGF-beta family.

93934:LOC107315243
gene id: 93934:LOC107315243
uniprot id: A0A8C2SSQ0
names: Similarity
messages: Belongs to the serpin family.

93934:MBOAT2
gene id: 93934:MBOAT2
uniprot id: A0A8C2TIQ4
names: Subcellular Location Annotation
messages: Membrane

93934:OPTN
gene id: 93934:OPTN
uniprot id: A0A8C2SVT6
names: Function
names: Subcellular Location Annotation
messages: Cytoplasmic vesicle
messages: Endosome
messages: Golgi apparatus
messages: May act by regulating membrane trafficking and cellular morphogenesis.
messages: Recycling endosome
messages: Vesicle
messages: autophagosome
messages: perinuclear region
messages: trans-Golgi network

93934:OSBPL3
gene id: 93934:OSBPL3
uniprot id: A0A8C2TK70
uniprot id: A0A8C2TKN4
names: Similarity
messages: Belongs to the OSBP family.

93934:ASPHD2
gene id: 93934:ASPHD2
uniprot id: A0A8C2Y969
names: Similarity
messages: Belongs to the aspartyl/asparaginyl beta-hydroxylase family.

93934:MEX3B
gene id: 93934:MEX3B
uniprot id: A0A8C2YH10
names: Subcellular Location Annotation
messages: Cytoplasm

93934:SLC35E1
gene id: 93934:SLC35E1
uniprot id: A0A8C2TQE9
names: Subcellular Location Annotation
messages: Membrane

93934:CLDN16
gene id: 93934:CLDN16
uniprot id: A0A8C2YCH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:AGRP
gene id: 93934:AGRP
uniprot id: C0A1C6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:CHRNA9
gene id: 93934:CHRNA9
uniprot id: A0A8C2U091
uniprot id: A0A8C2U3U2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:CLIC6
gene id: 93934:CLIC6
uniprot id: A0A8C2T4T3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Cytoplasm
messages: Members of this family may change from a globular, soluble state to a state where the N-terminal domain is inserted into the membrane and functions as chloride channel. A conformation change of the N-terminal domain is thought to expose hydrophobic surfaces that trigger membrane insertion.
messages: Membrane

93934:SLC4A5
gene id: 93934:SLC4A5
uniprot id: A0A8C2TJ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

93934:SNAP25
gene id: 93934:SNAP25
uniprot id: A0A8C2SPM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP-25 family.
messages: Cell membrane
messages: Plays an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion.
messages: synaptosome

93934:TDP1
gene id: 93934:TDP1
uniprot id: A0A8C2SKN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

93934:LRRFIP1
gene id: 93934:LRRFIP1
uniprot id: A0A8C2TTK5
uniprot id: A0A8C2TTQ5
uniprot id: A0A8C2YCT5
names: Similarity
messages: Belongs to the LRRFIP family.

93934:SNTG1
gene id: 93934:SNTG1
uniprot id: A0A8C2TIK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: cytoskeleton

93934:KIF2C
gene id: 93934:KIF2C
uniprot id: A0A8C2TDH6
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:HSPB8
gene id: 93934:HSPB8
uniprot id: A0A8C2TRM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Cytoplasm
messages: Displays temperature-dependent chaperone activity.

93934:PDE1C
gene id: 93934:PDE1C
uniprot id: A0A8C2T313
uniprot id: A0A8C2Y8D3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:THOP1
gene id: 93934:THOP1
uniprot id: A0A8C2THV4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

93934:PHKB
gene id: 93934:PHKB
uniprot id: A0A8C2TRH9
uniprot id: A0A8C2TUK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphorylase b kinase regulatory chain family.
messages: Cell membrane
messages: Membrane
messages: Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.

93934:CASD1
gene id: 93934:CASD1
uniprot id: A0A8C2YB83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PC-esterase family. CASD1 subfamily.
messages: Membrane

93934:APP
gene id: 93934:APP
uniprot id: A0A8C2SZW1
uniprot id: A0A8C2Y6V7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the APP family.
messages: Cell membrane
messages: Cell surface
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis.
messages: Golgi apparatus
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Nucleus
messages: Secreted

93934:YIPF6
gene id: 93934:YIPF6
uniprot id: A0A8C2SRH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

93934:CWC15
gene id: 93934:CWC15
uniprot id: A0A8C2SVD6
names: Similarity
messages: Belongs to the CWC15 family.

93934:KIF3B
gene id: 93934:KIF3B
uniprot id: A0A8C2SY67
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:MSX1
gene id: 93934:MSX1
uniprot id: A0A8C2YFS3
names: Subcellular Location Annotation
messages: Nucleus

93934:FAM163B
gene id: 93934:FAM163B
uniprot id: A0A8C2Y8F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM163 family.
messages: Membrane

93934:RAB33A
gene id: 93934:RAB33A
uniprot id: A0A8C2SY00
names: Similarity
messages: Belongs to the small GTPase superfamily. Rab family.

93934:TYSND1
gene id: 93934:TYSND1
uniprot id: A0A8C2TGS5
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1B family.
messages: Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids.
messages: Peroxisome
messages: The full-lengh TYSND1 is the active the proteolytic processing of PTS1- and PTS2-proteins and in self-cleavage, and intermolecular self-cleavage of TYSND1 down-regulates its protease activity.

93934:S100B
gene id: 93934:S100B
uniprot id: A0A8C2TNI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the S-100 family.
messages: Cytoplasm
messages: Nucleus
messages: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

93934:MTUS1
gene id: 93934:MTUS1
uniprot id: A0A8C2THW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MTUS1 family.
messages: Nucleus

93934:CLCN2
gene id: 93934:CLCN2
uniprot id: A0A8C2TTA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family. ClC-2/CLCN2 subfamily.
messages: Cell membrane
messages: Membrane

93934:PPP1R9A
gene id: 93934:PPP1R9A
uniprot id: A0A8C2TGX6
uniprot id: A0A8C2TH22
names: Subcellular Location Annotation
messages: cytoskeleton

93934:KCNH8
gene id: 93934:KCNH8
uniprot id: A0A8C2TNR7
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: The potassium channel is probably composed of a homo- or heterotetrameric complex of pore-forming alpha subunits that can associate with modulating beta subunits.

93934:GPRC6A
gene id: 93934:GPRC6A
uniprot id: A0A8C2TA76
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:TLX3
gene id: 93934:TLX3
uniprot id: A0A8C2TK31
names: Subcellular Location Annotation
messages: Nucleus

93934:CA4
gene id: 93934:CA4
uniprot id: A0A8C2YF91
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Cell membrane
messages: Interacts with SLC4A4.
messages: Membrane

93934:HHIPL1
gene id: 93934:HHIPL1
uniprot id: A0A8C2SQN0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SFXN4
gene id: 93934:SFXN4
uniprot id: A0A8C2UFP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane

93934:EGR1
gene id: 93934:EGR1
uniprot id: A0A8C2YHG5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus
messages: Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death.

93934:CMAS
gene id: 93934:CMAS
uniprot id: A0A8C2SUU1
names: Similarity
messages: Belongs to the CMP-NeuNAc synthase family.

93934:GRIA4
gene id: 93934:GRIA4
uniprot id: A0A8C2SSU4
uniprot id: A0A8C2SU41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:TEF
gene id: 93934:TEF
uniprot id: A0A8C2T9F3
uniprot id: A0A8C2TEU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. PAR subfamily.
messages: Nucleus

93934:KCNK13
gene id: 93934:KCNK13
uniprot id: A0A8C2SN93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:TFEB
gene id: 93934:TFEB
uniprot id: A0A8C2UBJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MiT/TFE family.
messages: Nucleus

93934:SLC30A4
gene id: 93934:SLC30A4
uniprot id: A0A8C2UAB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Membrane

93934:ATP8B3
gene id: 93934:ATP8B3
uniprot id: A0A8C2TG64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:STX19
gene id: 93934:STX19
uniprot id: A0A8C2U4E8
names: Similarity
messages: Belongs to the syntaxin family.

93934:LOC107316112
gene id: 93934:LOC107316112
uniprot id: A0A8C2U8N9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LOC107315429
gene id: 93934:LOC107315429
uniprot id: A0A8C2T2K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:CYYR1
gene id: 93934:CYYR1
uniprot id: A0A8C2SWG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CYYR1 family.
messages: Membrane

93934:YWHAE
gene id: 93934:YWHAE
uniprot id: A0A8C2TGR6
names: Similarity
messages: Belongs to the 14-3-3 family.

93934:LCA5
gene id: 93934:LCA5
uniprot id: A0A8C2SVH0
uniprot id: A0A8C2Y6P0
names: Similarity
messages: Belongs to the LCA5 family.

93934:SLC41A3
gene id: 93934:SLC41A3
uniprot id: A0A8C2TWJ4
uniprot id: A0A8C2TWP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a magnesium transporter.
messages: Belongs to the SLC41A transporter family.
messages: Membrane

93934:ADRB3
gene id: 93934:ADRB3
uniprot id: A0A8C2TU21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:LOC107320318
gene id: 93934:LOC107320318
uniprot id: A0A8C2TCG5
names: Similarity
messages: Belongs to the lst-2 family.

93934:FH
gene id: 93934:FH
uniprot id: A0A8C2TVU9
names: Function
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
messages: Catalyzes the hydration of fumarate to L-malate in the tricarboxylic acid (TCA) cycle to facilitate a transition step in the production of energy in the form of NADH.

93934:LOC107325785
gene id: 93934:LOC107325785
uniprot id: A0A8C2SV50
names: Similarity
messages: Belongs to the intermediate filament family.

93934:INHBA
gene id: 93934:INHBA
uniprot id: A0A8C2T2R3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

93934:TECPR1
gene id: 93934:TECPR1
uniprot id: A0A8C2TTR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TECPR1 family.
messages: Lysosome membrane
messages: autophagosome membrane

93934:RABGGTB
gene id: 93934:RABGGTB
uniprot id: A0A8C2TW32
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

93934:FUT10
gene id: 93934:FUT10
uniprot id: A0A8C2YBP8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

93934:IMPA2
gene id: 93934:IMPA2
uniprot id: A0A8C2T5M8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93934:KIF11
gene id: 93934:KIF11
uniprot id: A0A8C2YGH5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:APOOL
gene id: 93934:APOOL
uniprot id: A0A8C2U0J2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the apolipoprotein O/MICOS complex subunit Mic27 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

93934:TMED10
gene id: 93934:TMED10
uniprot id: A0A8C2UCQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:FOXO3
gene id: 93934:FOXO3
uniprot id: A0A8C2TAT5
names: Subcellular Location Annotation
messages: Nucleus

93934:CZH9orf64
gene id: 93934:CZH9orf64
uniprot id: A0A8C2TDH4
names: Function
names: Similarity
messages: Belongs to the queuosine salvage protein family.
messages: Involved in salvaging queuosine.

93934:NKAIN4
gene id: 93934:NKAIN4
uniprot id: A0A8C2SV05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

93934:NDUFAF2
gene id: 93934:NDUFAF2
uniprot id: A0A8C2SQ42
names: Similarity
messages: Belongs to the complex I NDUFA12 subunit family.

93934:NFYA
gene id: 93934:NFYA
uniprot id: A0A8C2YG36
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

93934:P2RY4
gene id: 93934:P2RY4
uniprot id: A0A8C2SUT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:ASIC4
gene id: 93934:ASIC4
uniprot id: A0A8C2YCG9
uniprot id: A0A8C2YCL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
messages: Membrane

93934:CRK
gene id: 93934:CRK
uniprot id: A0A8C2TJ92
names: Similarity
messages: Belongs to the CRK family.

93934:HEXB
gene id: 93934:HEXB
uniprot id: A0A8C2SQZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 20 family.
messages: Lysosome

93934:PGM2
gene id: 93934:PGM2
uniprot id: A0A8C2U3W5
names: Similarity
messages: Belongs to the phosphohexose mutase family.

93934:HGD
gene id: 93934:HGD
uniprot id: A0A8C2U145
names: Similarity
messages: Belongs to the homogentisate dioxygenase family.

93934:PRR5
gene id: 93934:PRR5
uniprot id: A0A8C2TX48
uniprot id: A0A8C2U055
names: Similarity
messages: Belongs to the PROTOR family.

93934:MAP3K9
gene id: 93934:MAP3K9
uniprot id: A0A8C2TXF0
names: Activity Regulation
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Homodimer.
messages: Homodimerization via the leucine zipper domains is required for autophosphorylation.

93934:SLC16A8
gene id: 93934:SLC16A8
uniprot id: A0A8C2YCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
messages: Membrane

93934:NDNF
gene id: 93934:NDNF
uniprot id: A0A8C2SWK0
names: Subcellular Location Annotation
messages: Secreted

93934:PKIA
gene id: 93934:PKIA
uniprot id: A0A8C2YBG1
names: Function
names: Similarity
messages: Belongs to the PKI family.
messages: Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.

93934:LOC107320565
gene id: 93934:LOC107320565
uniprot id: A0A8C2TST7
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:TWSG1
gene id: 93934:TWSG1
uniprot id: A0A8C2TAU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the twisted gastrulation protein family.
messages: Secreted

93934:MRPL28
gene id: 93934:MRPL28
uniprot id: A0A8C2TXX2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

93934:KDM3B
gene id: 93934:KDM3B
uniprot id: A0A8C2UIG0
names: Subcellular Location Annotation
messages: Nucleus

93934:ZFYVE9
gene id: 93934:ZFYVE9
uniprot id: A0A8C2TIW2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Early endosome membrane

93934:ADAM17
gene id: 93934:ADAM17
uniprot id: A0A8C2TFK3
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:WIF1
gene id: 93934:WIF1
uniprot id: A0A8C2TYP8
names: Caution
names: Function
messages: Binds to WNT proteins and inhibits their activities. May be involved in mesoderm segmentation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:KDELR3
gene id: 93934:KDELR3
uniprot id: A0A8C2TNC3
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:MED4
gene id: 93934:MED4
uniprot id: A0A8C2U901
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:NAA35
gene id: 93934:NAA35
uniprot id: A0A8C2TD49
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MAK10 family.
messages: Component of the N-terminal acetyltransferase C (NatC) complex, which is composed of NAA35, NAA38 and NAA30.
messages: Cytoplasm

93934:CCNE1
gene id: 93934:CCNE1
uniprot id: A0A8C2TTQ7
names: Similarity
messages: Belongs to the cyclin family. Cyclin E subfamily.

93934:LOC107323093
gene id: 93934:LOC107323093
uniprot id: A0A8C2T4J4
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Membrane

93934:VIPAS39
gene id: 93934:VIPAS39
uniprot id: A0A8C2U7T3
names: Subcellular Location Annotation
messages: Endosome
messages: Late endosome
messages: Vesicle

93934:BLM
gene id: 93934:BLM
uniprot id: A0A8C2UFX1
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

93934:CPXM2
gene id: 93934:CPXM2
uniprot id: A0A8C2UFU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Secreted

93934:SLC16A14
gene id: 93934:SLC16A14
uniprot id: A0A8C2TAI8
names: Subcellular Location Annotation
messages: Membrane

93934:SH3PXD2A
gene id: 93934:SH3PXD2A
uniprot id: A0A8C2UC05
uniprot id: A0A8C2YGT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3PXD2 family.
messages: Cytoplasm
messages: podosome

93934:RPL30
gene id: 93934:RPL30
uniprot id: A0A8C2SMV0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

93934:LOC107314850
gene id: 93934:LOC107314850
uniprot id: A0A8C2TJV1
names: Caution
names: Cofactor
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MED14
gene id: 93934:MED14
uniprot id: A0A8C2TZ47
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:USP37
gene id: 93934:USP37
uniprot id: A0A8C2TPI9
names: Similarity
messages: Belongs to the peptidase C19 family.

93934:NUP35
gene id: 93934:NUP35
uniprot id: A0A8C2TTI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nup35 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

93934:MSX2
gene id: 93934:MSX2
uniprot id: A0A8C2T8M9
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107312129
gene id: 93934:LOC107312129
uniprot id: A0A8C2T8V2
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

93934:SGCG
gene id: 93934:SGCG
uniprot id: A0A8C2SPC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
messages: Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
messages: cytoskeleton
messages: sarcolemma

93934:GPC4
gene id: 93934:GPC4
uniprot id: A0A8C2U2M0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

93934:SIN3A
gene id: 93934:SIN3A
uniprot id: A0A8C2T6B3
names: Subcellular Location Annotation
messages: Nucleus

93934:BCAT1
gene id: 93934:BCAT1
uniprot id: A0A8C2Y5X8
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

93934:HTR1B
gene id: 93934:HTR1B
uniprot id: A0A8C2SYH1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Homodimer. Heterodimer with HTR1D.
messages: Membrane

93934:LANCL1
gene id: 93934:LANCL1
uniprot id: A0A8C2YCS7
names: Similarity
messages: Belongs to the LanC-like protein family.

93934:EIF1AX
gene id: 93934:EIF1AX
uniprot id: A0A8C2U2I2
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

93934:ACOD1
gene id: 93934:ACOD1
uniprot id: A0A8C2YGH6
names: Similarity
messages: Belongs to the PrpD family.

93934:TMEFF1
gene id: 93934:TMEFF1
uniprot id: A0A8C2Y887
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:KLHL15
gene id: 93934:KLHL15
uniprot id: A0A8C2U464
names: Subcellular Location Annotation
messages: Nucleus

93934:RNF32
gene id: 93934:RNF32
uniprot id: A0A8C2SW36
names: Similarity
messages: Belongs to the RING-box family.

93934:DEDD
gene id: 93934:DEDD
uniprot id: A0A8C2SKU4
names: Subcellular Location Annotation
messages: nucleolus

93934:DACT2
gene id: 93934:DACT2
uniprot id: A0A8C2SU72
names: Similarity
messages: Belongs to the dapper family.

93934:DGLUCY
gene id: 93934:DGLUCY
uniprot id: A0A8C2SL48
names: Similarity
messages: Belongs to the D-glutamate cyclase family.

93934:SLC25A19
gene id: 93934:SLC25A19
uniprot id: A0A8C2UG17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:SPSB4
gene id: 93934:SPSB4
uniprot id: A0A8C2T4G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPSB family.
messages: Cytoplasm

93934:TMEM38A
gene id: 93934:TMEM38A
uniprot id: A0A8C2TS01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

93934:TENM4
gene id: 93934:TENM4
uniprot id: A0A8C2SZU4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family. Teneurin subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:C1GALT1
gene id: 93934:C1GALT1
uniprot id: A0A8C2TH50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.
messages: Glycosyltransferase that generates the core 1 O-glycan Gal-beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins.
messages: Membrane

93934:ADA2
gene id: 93934:ADA2
uniprot id: A0A8C2U5A0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. ADGF subfamily.
messages: Secreted

93934:PNO1
gene id: 93934:PNO1
uniprot id: A0A8C2YB43
names: Similarity
messages: Belongs to the PNO1 family.

93934:MYLK
gene id: 93934:MYLK
uniprot id: A0A8C2UJ37
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.

93934:AMD1
gene id: 93934:AMD1
uniprot id: A0A8C2T9V7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Essential for biosynthesis of the polyamines spermidine and spermine. Promotes maintenance and self-renewal of embryonic stem cells, by maintaining spermine levels.

93934:KIF4A
gene id: 93934:KIF4A
uniprot id: A0A8C2SX52
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:ELOVL6
gene id: 93934:ELOVL6
uniprot id: A0A8C2T2V0
uniprot id: A0A8C2T4C6
names: Caution
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Belongs to the ELO family. ELOVL6 subfamily.
messages: Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degree. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: N-Glycosylated.

93934:KCNK3
gene id: 93934:KCNK3
uniprot id: A0A8C2TLQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
messages: Membrane

93934:BCL2
gene id: 93934:BCL2
uniprot id: A0A8C2U1A2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Bcl-2 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion outer membrane
messages: Nucleus membrane

93934:NIPAL3
gene id: 93934:NIPAL3
uniprot id: A0A8C2Y752
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NIPA family.
messages: Membrane

93934:HNRNPU
gene id: 93934:HNRNPU
uniprot id: A0A8C2TPH4
names: Subcellular Location Annotation
messages: Nucleus

93934:CLDN23
gene id: 93934:CLDN23
uniprot id: A0A8C2TJ42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Membrane
messages: tight junction

93934:DYRK2
gene id: 93934:DYRK2
uniprot id: A0A8C2U072
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

93934:QSOX1
gene id: 93934:QSOX1
uniprot id: A0A8C2UK53
names: Function
names: Similarity
messages: Belongs to the quiescin-sulfhydryl oxidase (QSOX) family.
messages: Catalyzes the oxidation of sulfhydryl groups in peptide and protein thiols to disulfides with the reduction of oxygen to hydrogen peroxide.

93934:SNF8
gene id: 93934:SNF8
uniprot id: A0A8C2YGC7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

93934:KCNA1
gene id: 93934:KCNA1
uniprot id: A0A8C2U0G9
names: Subcellular Location Annotation
messages: Membrane

93934:UNK
gene id: 93934:UNK
uniprot id: A0A8C2YHF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unkempt family.
messages: Cytoplasm

93934:SAP30L
gene id: 93934:SAP30L
uniprot id: A0A8C2T724
names: Similarity
messages: Belongs to the SAP30 family.

93934:LOC107312849
gene id: 93934:LOC107312849
uniprot id: A0A8C2U2Q4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:RCL1
gene id: 93934:RCL1
uniprot id: A0A8C2SU50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: Does not have cyclase activity. Plays a role in 40S-ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA.
messages: nucleolus

93934:SEC11A
gene id: 93934:SEC11A
uniprot id: A0A8C2SMX2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Component of the signal peptidase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:NEMP2
gene id: 93934:NEMP2
uniprot id: A0A8C2TUB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NEMP family.
messages: Nucleus inner membrane

93934:LOC107310166
gene id: 93934:LOC107310166
uniprot id: A0A8C2THF3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:LANCL2
gene id: 93934:LANCL2
uniprot id: A0A8C2SKA8
names: Similarity
messages: Belongs to the LanC-like protein family.

93934:TBXAS1
gene id: 93934:TBXAS1
uniprot id: A0A8C2UCS1
uniprot id: A0A8C2YH18
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:YAF2
gene id: 93934:YAF2
uniprot id: A0A8C2TQG7
names: Subcellular Location Annotation
messages: Nucleus

93934:CCL20
gene id: 93934:CCL20
uniprot id: A0A8C2TA68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the intercrine beta (chemokine CC) family.
messages: Secreted

93934:YWHAH
gene id: 93934:YWHAH
uniprot id: A0A8C2TJF9
names: Similarity
messages: Belongs to the 14-3-3 family.

93934:LOC107314046
gene id: 93934:LOC107314046
uniprot id: A0A8C2SYP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107323562
gene id: 93934:LOC107323562
uniprot id: A0A8C2YB21
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

93934:NKD1
gene id: 93934:NKD1
uniprot id: A0A8C2TTV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKD family.
messages: Cell autonomous antagonist of the canonical Wnt signaling pathway.
messages: Cell membrane
messages: Cytoplasm
messages: Membrane

93934:SPARCL1
gene id: 93934:SPARCL1
uniprot id: A0A8C2TE67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPARC family.
messages: extracellular matrix

93934:LOC107320368
gene id: 93934:LOC107320368
uniprot id: A0A8C2YB99
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

93934:AIDA
gene id: 93934:AIDA
uniprot id: A0A8C2T488
names: Similarity
messages: Belongs to the AIDA family.

93934:PARD6B
gene id: 93934:PARD6B
uniprot id: A0A8C2T4R4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAR6 family.
messages: Cytoplasm
messages: tight junction

93934:LOC107309544
gene id: 93934:LOC107309544
uniprot id: A0A8C2TSN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dienelactone hydrolase family.
messages: cytosol

93934:LOC107324396
gene id: 93934:LOC107324396
uniprot id: A0A8C2TSQ8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:SMARCB1
gene id: 93934:SMARCB1
uniprot id: A0A8C2Y9F1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNF5 family.
messages: Component of the multiprotein chromatin-remodeling complexes SWI/SNF.
messages: Nucleus

93934:RAB4A
gene id: 93934:RAB4A
uniprot id: A0A8C2STV0
uniprot id: A0A8C2SVV1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport.

93934:CAMKMT
gene id: 93934:CAMKMT
uniprot id: A0A8C2TD24
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:GLRX2
gene id: 93934:GLRX2
uniprot id: A0A8C2UJK7
names: Function
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

93934:CALB2
gene id: 93934:CALB2
uniprot id: A0A8C2T7M3
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Calretinin is a calcium-binding protein which is abundant in auditory neurons.

93934:KPNB1
gene id: 93934:KPNB1
uniprot id: A0A8C2SPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the importin beta family. Importin beta-1 subfamily.
messages: Cytoplasm

93934:INS
gene id: 93934:INS
uniprot id: A0A8C2U8B5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the insulin family.
messages: Heterodimer of a B chain and an A chain linked by two disulfide bonds.
messages: Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
messages: Secreted

93934:CLVS2
gene id: 93934:CLVS2
uniprot id: A0A8C2Y9L5
names: Subcellular Location Annotation
messages: Early endosome membrane
messages: Endosome membrane
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network membrane

93934:GOSR2
gene id: 93934:GOSR2
uniprot id: A0A8C2U6N3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOSR2 family.
messages: Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
messages: Membrane

93934:MYB
gene id: 93934:MYB
uniprot id: A0A8C2T8U9
names: Subcellular Location Annotation
messages: Nucleus

93934:VKORC1L1
gene id: 93934:VKORC1L1
uniprot id: A0A8C2TDI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VKOR family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:MARCHF4
gene id: 93934:MARCHF4
uniprot id: A0A8C2TMN7
names: Subcellular Location Annotation
messages: Membrane

93934:PTPRD
gene id: 93934:PTPRD
uniprot id: A0A8C2Y605
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.

93934:TRAPPC3L
gene id: 93934:TRAPPC3L
uniprot id: A0A8C2Y9M8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Homodimer.
messages: May play a role in vesicular transport from endoplasmic reticulum to Golgi.
messages: cis-Golgi network

93934:ATP8A2
gene id: 93934:ATP8A2
uniprot id: A0A8C2SM88
uniprot id: A0A8C2SPW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:LRRC8B
gene id: 93934:LRRC8B
uniprot id: A0A8C2T6W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRRC8 family.
messages: Cell membrane
messages: Membrane

93934:SHROOM1
gene id: 93934:SHROOM1
uniprot id: A0A8C2UCP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shroom family.
messages: cytoskeleton

93934:EIF3H
gene id: 93934:EIF3H
uniprot id: A0A8C2SY35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit H family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Cytoplasm

93934:DYNLL2
gene id: 93934:DYNLL2
uniprot id: A0A8C2U578
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:GLB1L2
gene id: 93934:GLB1L2
uniprot id: A0A8C2Y871
names: Similarity
messages: Belongs to the glycosyl hydrolase 35 family.

93934:LOC107305933
gene id: 93934:LOC107305933
uniprot id: A0A8C2T8E6
names: Cofactor
names: Function
names: Subunit
messages: Binds 1 zinc ion per subunit.
messages: Homotetramer.
messages: Involved in the regulation of homocysteine metabolism.

93934:FGR
gene id: 93934:FGR
uniprot id: A0A8C2YE55
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:ADAM20
gene id: 93934:ADAM20
uniprot id: A0A8C2TTD4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SFMBT2
gene id: 93934:SFMBT2
uniprot id: A0A8C2SWY8
names: Subcellular Location Annotation
messages: Nucleus

93934:RPL31
gene id: 93934:RPL31
uniprot id: A0A8C2SS35
names: Similarity
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eL31 family.
messages: Component of the large ribosomal subunit.

93934:PTDSS1
gene id: 93934:PTDSS1
uniprot id: A0A8C2SMR6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phosphatidyl serine synthase family.
messages: Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) is replaced by L-serine.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107309799
gene id: 93934:LOC107309799
uniprot id: A0A8C2SKC1
names: Similarity
messages: Belongs to the beta type-B retroviral polymerase family. HERV class-II K(HML-2) pol subfamily.

93934:LOC107312133
gene id: 93934:LOC107312133
uniprot id: A0A8C2T8D6
names: Similarity
messages: Belongs to the GST superfamily. Alpha family.

93934:NTMT1
gene id: 93934:NTMT1
uniprot id: A0A8C2UDD4
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

93934:PCNP
gene id: 93934:PCNP
uniprot id: A0A8C2U491
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Interacts with UHRF2/NIRF.
messages: May be involved in cell cycle regulation.
messages: Nucleus

93934:TTC39C
gene id: 93934:TTC39C
uniprot id: A0A8C2TD30
names: Similarity
messages: Belongs to the TTC39 family.

93934:METTL16
gene id: 93934:METTL16
uniprot id: A0A8C2U407
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. METTL16/RlmF family.
messages: RNA N6-methyltransferase that methylates adenosine residues at the N(6) position of a subset of RNAs and is involved in S-adenosyl-L-methionine homeostasis by regulating expression of MAT2A transcripts. Able to N6-methylate a subset of mRNAs and U6 small nuclear RNAs (U6 snRNAs). In contrast to the METTL3-METTL14 heterodimer, only able to methylate a limited number of RNAs: requires both a 5'UACAGAGAA-3' nonamer sequence and a specific RNA structure.

93934:ITGA8
gene id: 93934:ITGA8
uniprot id: A0A8C2T053
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the integrin alpha chain family.
messages: Membrane

93934:SPTSSB
gene id: 93934:SPTSSB
uniprot id: A0A8C2YFH1
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107316629
gene id: 93934:LOC107316629
uniprot id: A0A8C2SRR5
uniprot id: A0A8C2SRR6
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:RHBDD1
gene id: 93934:RHBDD1
uniprot id: A0A8C2T8S2
names: Subcellular Location Annotation
messages: Membrane

93934:WARS1
gene id: 93934:WARS1
uniprot id: A0A8C2SR22
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:TOMM7
gene id: 93934:TOMM7
uniprot id: A0A8C2TME8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:HOXD11
gene id: 93934:HOXD11
uniprot id: A0A8C2U4K5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Abd-B homeobox family.
messages: Nucleus

93934:SNRPA1
gene id: 93934:SNRPA1
uniprot id: A0A8C2YHC5
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

93934:CHMP5
gene id: 93934:CHMP5
uniprot id: A0A8C2TSX0
names: Similarity
messages: Belongs to the SNF7 family.

93934:EHD3
gene id: 93934:EHD3
uniprot id: A0A8C2SP74
names: Subcellular Location Annotation
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: cilium membrane

93934:TLR7
gene id: 93934:TLR7
uniprot id: A0A8C2U7H9
uniprot id: G3XEP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Endoplasmic reticulum membrane
messages: Lysosome
messages: Membrane
messages: phagosome

93934:IGF1
gene id: 93934:IGF1
uniprot id: A0A8C2UAQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

93934:ALOX5AP
gene id: 93934:ALOX5AP
uniprot id: A0A8C2UBQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAPEG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TXLNG
gene id: 93934:TXLNG
uniprot id: A0A8C2U7K5
names: Similarity
messages: Belongs to the taxilin family.

93934:VWF
gene id: 93934:VWF
uniprot id: A0A8C2U1R5
names: Subcellular Location Annotation
names: Subunit
messages: Multimeric. Interacts with F8.
messages: extracellular matrix

93934:GPR37L1
gene id: 93934:GPR37L1
uniprot id: A0A8C2T2X3
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:GPBP1L1
gene id: 93934:GPBP1L1
uniprot id: A0A8C2THM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vasculin family.
messages: Nucleus

93934:GPR156
gene id: 93934:GPR156
uniprot id: A0A8C2U2E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 3 family. GABA-B receptor subfamily.
messages: Cell membrane
messages: Membrane

93934:SSTR2
gene id: 93934:SSTR2
uniprot id: A0A8C2UG25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer and heterodimer with SSTR3 and SSTR5. Heterodimerization with SSTR3 inactivates SSTR3 receptor function. Heterodimerization with SSTR5 is enhanced by agonist stimulation of SSTR2 and increases SSTR2 cell growth inhibition activity. Following agonist stimulation, homodimers dissociate into monomers which is required for receptor internalization. Interacts with beta-arrestin; this interaction is necessary for receptor internalization and is destabilized by heterodimerization with SSTR5 which results in increased recycling of SSTR2 to the cell surface. Interacts (via C-terminus) with SHANK1 (via PDZ domain).
messages: Membrane
messages: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

93934:DYRK1A
gene id: 93934:DYRK1A
uniprot id: A0A8C2T8Q1
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily.

93934:KDM1A
gene id: 93934:KDM1A
uniprot id: A0A8C2TZ14
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the flavin monoamine oxidase family.
messages: Histone demethylase that can demethylate both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me. May play a role in the repression of neuronal genes. Alone, it is unable to demethylate H3K4me on nucleosomes and requires the presence of RCOR1/CoREST to achieve such activity.
messages: Nucleus
messages: The SWIRM domain may act as an anchor site for a histone tail.

93934:MDFI
gene id: 93934:MDFI
uniprot id: A0A8C2U879
names: Similarity
messages: Belongs to the MDFI family.

93934:SHC1
gene id: 93934:SHC1
uniprot id: A0A8C2TSZ7
uniprot id: A0A8C2TUR6
names: Subcellular Location Annotation
messages: Cytoplasm

93934:LHPP
gene id: 93934:LHPP
uniprot id: A0A8C2Y595
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily.

93934:FAM135B
gene id: 93934:FAM135B
uniprot id: A0A8C2TFB9
names: Similarity
messages: Belongs to the FAM135 family.

93934:TMPRSS15
gene id: 93934:TMPRSS15
uniprot id: A0A8C2SZK0
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMBT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LOC107312841
gene id: 93934:LOC107312841
uniprot id: A0A8C2U2L1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tumor necrosis factor family.
messages: Membrane
messages: Secreted

93934:SIM1
gene id: 93934:SIM1
uniprot id: A0A8C2TG37
names: Subcellular Location Annotation
messages: Nucleus

93934:SCNN1B
gene id: 93934:SCNN1B
uniprot id: A0A8C2TD41
names: Subcellular Location Annotation
messages: Membrane

93934:PRKCH
gene id: 93934:PRKCH
uniprot id: A0A8C2T3E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cytoplasm

93934:KDELR2
gene id: 93934:KDELR2
uniprot id: A0A8C2TXW4
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: COPI-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:RAB29
gene id: 93934:RAB29
uniprot id: A0A8C2TYD1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

93934:TXLNA
gene id: 93934:TXLNA
uniprot id: A0A8C2SQI6
names: Similarity
messages: Belongs to the taxilin family.

93934:SF3B5
gene id: 93934:SF3B5
uniprot id: A0A8C2T0E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SF3B5 family.
messages: Component of the spliceosome B complex.
messages: Nucleus

93934:NMU
gene id: 93934:NMU
uniprot id: A0A8C2TI44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NmU family.
messages: Secreted

93934:FAM72A
gene id: 93934:FAM72A
uniprot id: A0A8C2TVM1
names: Similarity
messages: Belongs to the FAM72 family.

93934:MAPKAP1
gene id: 93934:MAPKAP1
uniprot id: A0A8C2TFZ0
names: Similarity
messages: Belongs to the SIN1 family.

93934:OLFM1
gene id: 93934:OLFM1
uniprot id: A0A8C2T797
uniprot id: A0A8C2TA97
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

93934:NPRL3
gene id: 93934:NPRL3
uniprot id: A0A8C2YEC2
uniprot id: A0A8C2YED8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway.
messages: Belongs to the NPR3 family.
messages: Lysosome

93934:GATA5
gene id: 93934:GATA5
uniprot id: A0A8C2SUE1
names: Subcellular Location Annotation
messages: Nucleus

93934:AGL
gene id: 93934:AGL
uniprot id: A0A8C2SKF1
uniprot id: A0A8C2SMK0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

93934:ILDR1
gene id: 93934:ILDR1
uniprot id: A0A8C2U3P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the immunoglobulin superfamily. LISCH7 family.
messages: Membrane
messages: tight junction

93934:RDM1
gene id: 93934:RDM1
uniprot id: A0A8C2U748
names: Subcellular Location Annotation
messages: Cytoplasm
messages: nucleolus

93934:DUSP1
gene id: 93934:DUSP1
uniprot id: A0A8C2TCF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Nucleus

93934:MKX
gene id: 93934:MKX
uniprot id: A0A8C2SU43
names: Subcellular Location Annotation
messages: Nucleus

93934:TRAP1
gene id: 93934:TRAP1
uniprot id: C7G495
names: Similarity
messages: Belongs to the heat shock protein 90 family.

93934:FRK
gene id: 93934:FRK
uniprot id: A0A8C2TA92
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:TMEM200C
gene id: 93934:TMEM200C
uniprot id: A0A8C2T894
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

93934:SUV39H2
gene id: 93934:SUV39H2
uniprot id: A0A8C2SWC5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily.
messages: Nucleus
messages: centromere

93934:TFAP2D
gene id: 93934:TFAP2D
uniprot id: A0A8C2SQH8
names: Similarity
messages: Belongs to the AP-2 family.

93934:BUD31
gene id: 93934:BUD31
uniprot id: A0A8C2SSA3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

93934:LOC107324388
gene id: 93934:LOC107324388
uniprot id: A0A8C2TTN8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:CLTA
gene id: 93934:CLTA
uniprot id: A0A8C2TJ73
uniprot id: A0A8C2TJC5
uniprot id: A0A8C2TMC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

93934:TMLHE
gene id: 93934:TMLHE
uniprot id: A0A8C2TZI1
uniprot id: A0A8C2U0R4
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

93934:LOC107324115
gene id: 93934:LOC107324115
uniprot id: A0A8C2SXR8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:FLVCR1
gene id: 93934:FLVCR1
uniprot id: A0A8C2T6M6
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107313444
gene id: 93934:LOC107313444
uniprot id: A0A8C2SPE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UDP-glycosyltransferase family.
messages: Membrane

93934:CRYBA1
gene id: 93934:CRYBA1
uniprot id: A0A8C2TP49
names: Similarity
messages: Belongs to the beta/gamma-crystallin family.

93934:AIFM1
gene id: 93934:AIFM1
uniprot id: A0A8C2SW16
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase family.

93934:HSF2
gene id: 93934:HSF2
uniprot id: A0A8C2TC78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

93934:MANBA
gene id: 93934:MANBA
uniprot id: A0A8C2T3S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 2 family.
messages: Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides.
messages: Lysosome
messages: Monomer.

93934:SMAD6
gene id: 93934:SMAD6
uniprot id: A0A8C2UGP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:LOC107325044
gene id: 93934:LOC107325044
uniprot id: A0A8C2YG73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

93934:EGFL7
gene id: 93934:EGFL7
uniprot id: A0A8C2T8V1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:NDFIP2
gene id: 93934:NDFIP2
uniprot id: A0A8C2U9X0
uniprot id: A0A8C2UDB0
names: Subcellular Location Annotation
messages: Membrane

93934:PER2
gene id: 93934:PER2
uniprot id: A0A8C2T2H0
uniprot id: Q9I952
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:KCNQ5
gene id: 93934:KCNQ5
uniprot id: A0A8C2T2W6
uniprot id: A0A8C2T586
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:MAGT1
gene id: 93934:MAGT1
uniprot id: A0A8C2U065
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:RWDD3
gene id: 93934:RWDD3
uniprot id: A0A8C2SKT7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:LOC107308554
gene id: 93934:LOC107308554
uniprot id: A0A8C2SXP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPOT14 family.
messages: Cytoplasm
messages: Nucleus

93934:TENT5B
gene id: 93934:TENT5B
uniprot id: A0A8C2TZR0
names: Similarity
messages: Belongs to the TENT family.

93934:NFE2L1
gene id: 93934:NFE2L1
uniprot id: A0A8C2U7P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. CNC subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus

93934:LGSN
gene id: 93934:LGSN
uniprot id: A0A8C2T3X8
names: Similarity
messages: Belongs to the glutamine synthetase family.

93934:AKAP12
gene id: 93934:AKAP12
uniprot id: A0A8C2T5F3
uniprot id: A0A8C2Y8S1
names: Subcellular Location Annotation
messages: Membrane

93934:LMBR1
gene id: 93934:LMBR1
uniprot id: A0A8C2SU21
names: Similarity
messages: Belongs to the LIMR family.

93934:WSCD1
gene id: 93934:WSCD1
uniprot id: A0A8C2UA30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WSCD family.
messages: Membrane

93934:AP1S3
gene id: 93934:AP1S3
uniprot id: A0A8C2T2K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus
messages: clathrin-coated pit

93934:ACAD9
gene id: 93934:ACAD9
uniprot id: A0A8C2TP00
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93934:LOC107316409
gene id: 93934:LOC107316409
uniprot id: A0A8C2TPM6
names: Subcellular Location Annotation
messages: Cytoplasm

93934:CALCR
gene id: 93934:CALCR
uniprot id: A0A8C2TFU5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Interacts with GPRASP2.
messages: Membrane

93934:BZW2
gene id: 93934:BZW2
uniprot id: A0A8C2TKT3
names: Similarity
messages: Belongs to the BZW family.

93934:CHRNA1
gene id: 93934:CHRNA1
uniprot id: A0A8C2U4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:LOC107306105
gene id: 93934:LOC107306105
uniprot id: A0A8C2SW98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the insulin family.
messages: Secreted

93934:KEF80 p06
gene id: 93934:KEF80_p06
uniprot id: Q8SEW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 3 family.
messages: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity of complex I.
messages: Mitochondrion membrane

93934:GPC5
gene id: 93934:GPC5
uniprot id: A0A8C2U7W0
uniprot id: A0A8C2UBV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glypican family.
messages: Cell membrane
messages: Cell surface proteoglycan that bears heparan sulfate.

93934:ALOX5
gene id: 93934:ALOX5
uniprot id: A0A8C2U5Y4
names: Caution
names: Similarity
messages: Belongs to the lipoxygenase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:XK
gene id: 93934:XK
uniprot id: A0A8C2U1N1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:MTR
gene id: 93934:MTR
uniprot id: A0A8C2U546
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the vitamin-B12 dependent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from methylcob(III)alamin (MeCbl) to homocysteine, yielding enzyme-bound cob(I)alamin and methionine in the cytosol. MeCbl is an active form of cobalamin (vitamin B12) used as a cofactor for methionine biosynthesis. Cob(I)alamin form is regenerated to MeCbl by a transfer of a methyl group from 5-methyltetrahydrofolate. The processing of cobalamin in the cytosol occurs in a multiprotein complex composed of at least MMACHC, MMADHC, MTRR (methionine synthase reductase) and MTR which may contribute to shuttle safely and efficiently cobalamin towards MTR in order to produce methionine.
messages: Cytoplasm
messages: Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.

93934:LAMTOR3
gene id: 93934:LAMTOR3
uniprot id: A0A8C2T6A7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LAMTOR3 family.
messages: Endosome membrane
messages: Late endosome membrane

93934:XRCC3
gene id: 93934:XRCC3
uniprot id: A0A8C2SRG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Cytoplasm
messages: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions.
messages: Nucleus

93934:GAPDH
gene id: 93934:GAPDH
uniprot id: Q05025
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate (By similarity). Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC (By similarity).
messages: Homotetramer.
messages: Nucleus
messages: S-nitrosylation of Cys-150 leads to translocation to the nucleus.
messages: cytoskeleton
messages: cytosol

93934:PIM3
gene id: 93934:PIM3
uniprot id: Q9PU85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily.
messages: Cytoplasm
messages: Proto-oncogene with serine/threonine kinase activity that can prevent apoptosis and promote cell survival and protein translation.

93934:TIRAP
gene id: 93934:TIRAP
uniprot id: A0A8C2T4B7
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Adapter involved in the TLR2 and TLR4 signaling pathways in the innate immune response.
messages: Cell membrane
messages: Cytoplasm
messages: Homodimer.
messages: Membrane

93934:NARF
gene id: 93934:NARF
uniprot id: A0A8C2UFJ1
names: Similarity
messages: Belongs to the NARF family.

93934:GNB4
gene id: 93934:GNB4
uniprot id: A0A8C2TR20
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

93934:ALG9
gene id: 93934:ALG9
uniprot id: A0A8C2TTS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:PSMD4
gene id: 93934:PSMD4
uniprot id: A0A8C2TWB1
names: Similarity
messages: Belongs to the proteasome subunit S5A family.

93934:CNN2
gene id: 93934:CNN2
uniprot id: A0A8C2YAQ5
names: Function
names: Similarity
messages: Belongs to the calponin family.
messages: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

93934:LOC107308653
gene id: 93934:LOC107308653
uniprot id: A0A8C2TE27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

93934:LOC107320367
gene id: 93934:LOC107320367
uniprot id: A0A8C2TLZ9
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

93934:SNX11
gene id: 93934:SNX11
uniprot id: A0A8C2UBN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane

93934:HOXA7
gene id: 93934:HOXA7
uniprot id: A0A8C2TNX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Antp homeobox family.
messages: Nucleus

93934:TRMT61A
gene id: 93934:TRMT61A
uniprot id: A0A8C2STZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

93934:LOC107318315
gene id: 93934:LOC107318315
uniprot id: A0A8C2U032
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

93934:LOC107317376
gene id: 93934:LOC107317376
uniprot id: A0A8C2TYG3
names: Similarity
messages: Belongs to the UPF0046 family.

93934:MYO10
gene id: 93934:MYO10
uniprot id: A0A8C2TV18
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:OGN
gene id: 93934:OGN
uniprot id: Q9DE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Tissue Specificity
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily.
messages: Expressed in many tissues.
messages: Induces bone formation in conjunction with TGF-beta-1 or TGF-beta-2.
messages: extracellular matrix

93934:CDK5R2
gene id: 93934:CDK5R2
uniprot id: A0A8C2TQM2
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

93934:SH3GL2
gene id: 93934:SH3GL2
uniprot id: A0A8C2TA82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Membrane

93934:PTPN1
gene id: 93934:PTPN1
uniprot id: A0A8C2T6S7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.

93934:SOX21
gene id: 93934:SOX21
uniprot id: A0A8C2U862
names: Subcellular Location Annotation
messages: Nucleus

93934:PNLDC1
gene id: 93934:PNLDC1
uniprot id: A0A8C2SY72
names: Similarity
messages: Belongs to the CAF1 family.

93934:PEX16
gene id: 93934:PEX16
uniprot id: A0A8C2YD36
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-16 family.
messages: Peroxisome membrane

93934:MMP7
gene id: 93934:MMP7
uniprot id: A0A8C2SV93
names: Similarity
messages: Belongs to the peptidase M10A family.

93934:RNF146
gene id: 93934:RNF146
uniprot id: A0A8C2TDB1
names: Domain
names: Function
names: PTM
names: Subcellular Location Annotation
messages: E3 ubiquitin-protein ligase that specifically binds poly-ADP-ribosylated proteins and mediates their ubiquitination and subsequent degradation.
messages: The WWE domain mediates non-covalent poly(ADP-ribose)-binding.
messages: Ubiquitinated; autoubiquitinated.
messages: cytosol

93934:AKT1
gene id: 93934:AKT1
uniprot id: A0A8C2SRG7
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. RAC subfamily.

93934:SV2B
gene id: 93934:SV2B
uniprot id: A0A8C2YH49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily.
messages: Membrane
messages: synaptic vesicle membrane

93934:RPS14
gene id: 93934:RPS14
uniprot id: A0A8C2T407
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

93934:NSMCE4A
gene id: 93934:NSMCE4A
uniprot id: A0A8C2UA99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus
messages: telomere

93934:CHST4
gene id: 93934:CHST4
uniprot id: A0A8C2SUV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

93934:SLC37A4
gene id: 93934:SLC37A4
uniprot id: A0A8C2TI86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Organophosphate:Pi antiporter (OPA) (TC 2.A.1.4) family.
messages: Membrane

93934:MOXD1
gene id: 93934:MOXD1
uniprot id: A0A8C2T9B4
names: Similarity
messages: Belongs to the copper type II ascorbate-dependent monooxygenase family.

93934:CEP55
gene id: 93934:CEP55
uniprot id: A0A8C2U9C5
uniprot id: A0A8C2YG87
names: Subcellular Location Annotation
messages: Cytoplasm

93934:NAP1L1
gene id: 93934:NAP1L1
uniprot id: A0A8C2TX57
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

93934:RC3H2
gene id: 93934:RC3H2
uniprot id: A0A8C2YAP6
names: Subcellular Location Annotation
messages: P-body

93934:LOC107307985
gene id: 93934:LOC107307985
uniprot id: A0A8C2YE81
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CAPN6
gene id: 93934:CAPN6
uniprot id: A0A8C2U2L3
uniprot id: A0A8C2YEY4
names: Similarity
messages: Belongs to the peptidase C2 family.

93934:PDE3B
gene id: 93934:PDE3B
uniprot id: A0A8C2SWK4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:SULF1
gene id: 93934:SULF1
uniprot id: A0A8C2THM7
uniprot id: A0A8C2TL43
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:ITFG1
gene id: 93934:ITFG1
uniprot id: A0A8C2YD45
names: Similarity
messages: Belongs to the TIP family.

93934:PTPA
gene id: 93934:PTPA
uniprot id: A0A8C2UAS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93934:MRPL18
gene id: 93934:MRPL18
uniprot id: A0A8C2T1Q6
names: Similarity
messages: Belongs to the universal ribosomal protein uL18 family.

93934:SSH1
gene id: 93934:SSH1
uniprot id: A0A8C2Y8H4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

93934:ADGRB1
gene id: 93934:ADGRB1
uniprot id: A0A8C2TDU7
uniprot id: A0A8C2TGC5
uniprot id: A0A8C2TIU6
names: Subcellular Location Annotation
messages: Membrane

93934:TYRP1
gene id: 93934:TYRP1
uniprot id: A0A8C2Y606
uniprot id: A9Y149
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

93934:UPK1B
gene id: 93934:UPK1B
uniprot id: A0A8C2U6D6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Heterodimer with uroplakin-3A (UPK3A) or uroplakin-3B (UPK3B).
messages: Membrane

93934:PPP3CB
gene id: 93934:PPP3CB
uniprot id: A0A8C2TY91
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.

93934:SLC25A5
gene id: 93934:SLC25A5
uniprot id: A0A8C2U5T5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Monomer.

93934:ADAMTS12
gene id: 93934:ADAMTS12
uniprot id: A0A8C2Y802
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:ELP4
gene id: 93934:ELP4
uniprot id: A0A8C2TUP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

93934:CRY1
gene id: 93934:CRY1
uniprot id: A0A8C2U3Q7
names: Similarity
messages: Belongs to the DNA photolyase class-1 family.

93934:LNPK
gene id: 93934:LNPK
uniprot id: A0A8C2U7D9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Homodimer; homodimerization requires the C4-type zinc finger motif and decreases during mitosis in a phosphorylation-dependent manner.
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

93934:PEX7
gene id: 93934:PEX7
uniprot id: A0A8C2T8N8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

93934:COMT
gene id: 93934:COMT
uniprot id: A0A8C2UBT9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones.

93934:DOK3
gene id: 93934:DOK3
uniprot id: A0A8C2YA58
names: Similarity
messages: Belongs to the DOK family. Type A subfamily.

93934:CSNK1G1
gene id: 93934:CSNK1G1
uniprot id: A0A8C2SMB2
names: Similarity
messages: Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.

93934:RIOK2
gene id: 93934:RIOK2
uniprot id: A0A8C2TLF2
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

93934:VIRMA
gene id: 93934:VIRMA
uniprot id: A0A8C2SMK4
names: Similarity
messages: Belongs to the vir family.

93934:CCNYL1
gene id: 93934:CCNYL1
uniprot id: A0A8C2TXJ0
names: Similarity
messages: Belongs to the cyclin family. Cyclin Y subfamily.

93934:KCNV1
gene id: 93934:KCNV1
uniprot id: A0A8C2Y7D2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the potassium channel family. V (TC 1.A.1.2) subfamily. Kv8.1/KCNV1 sub-subfamily.
messages: Heteromultimer with KCNB1 and KCNB2. Interacts with KCNC4 and KCND1.
messages: Membrane
messages: Potassium channel subunit that does not form functional channels by itself. Modulates KCNB1 and KCNB2 channel activity by shifting the threshold for inactivation to more negative values and by slowing the rate of inactivation. Can down-regulate the channel activity of KCNB1, KCNB2, KCNC4 and KCND1, possibly by trapping them in intracellular membranes.

93934:HABP2
gene id: 93934:HABP2
uniprot id: A0A8C2UE36
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:LOC107313488
gene id: 93934:LOC107313488
uniprot id: A0A8C2YAF1
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:CPNE2
gene id: 93934:CPNE2
uniprot id: A0A8C2TL91
names: Similarity
messages: Belongs to the copine family.

93934:LOC107308927
gene id: 93934:LOC107308927
uniprot id: A0A8C2TIV5
names: Similarity
messages: Belongs to the glycosyl hydrolase 56 family.

93934:S1PR1
gene id: 93934:S1PR1
uniprot id: A0A8C2UER5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:TGM2
gene id: 93934:TGM2
uniprot id: A0A8C2SY02
names: Cofactor
names: Similarity
messages: Belongs to the transglutaminase superfamily. Transglutaminase family.
messages: Binds 1 Ca(2+) ion per subunit.

93934:NODAL
gene id: 93934:NODAL
uniprot id: A0A8C2YDI9
names: Similarity
messages: Belongs to the TGF-beta family.

93934:DHX29
gene id: 93934:DHX29
uniprot id: A0A8C2SMY0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity.
messages: Belongs to the DEAD box helicase family. DEAH subfamily.
messages: Cytoplasm
messages: Part of the 43S pre-initiation complex (PIC).

93934:WBP4
gene id: 93934:WBP4
uniprot id: A0A8C2YGK2
names: Subcellular Location Annotation
messages: Nucleus

93934:SNRPD3
gene id: 93934:SNRPD3
uniprot id: A0A8C2YA04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

93934:LOC107322463
gene id: 93934:LOC107322463
uniprot id: A0A8C2TED4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.
messages: Nucleus

93934:MVD
gene id: 93934:MVD
uniprot id: A0A8C2TTG1
names: Function
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.
messages: Catalyzes the ATP dependent decarboxylation of (R)-5-diphosphomevalonate to form isopentenyl diphosphate (IPP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoids and sterol synthesis.

93934:PLA2R1
gene id: 93934:PLA2R1
uniprot id: A0A8C2YD31
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CORO6
gene id: 93934:CORO6
uniprot id: A0A8C2TLD9
names: Similarity
messages: Belongs to the WD repeat coronin family.

93934:DNMBP
gene id: 93934:DNMBP
uniprot id: A0A8C2U857
names: Subcellular Location Annotation
messages: Cell junction
messages: Golgi stack
messages: cytoskeleton

93934:SOX2
gene id: 93934:SOX2
uniprot id: A0A8C2TUY3
names: Subcellular Location Annotation
messages: Nucleus

93934:PTAFR
gene id: 93934:PTAFR
uniprot id: A0A8C2TXJ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with ARRB1.
messages: Membrane

93934:CTSZ
gene id: 93934:CTSZ
uniprot id: A0A8C2Y820
names: Similarity
messages: Belongs to the peptidase C1 family.

93934:ASZ1
gene id: 93934:ASZ1
uniprot id: A0A8C2TIW8
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Interacts with DDX4, PIWIL1, RANBP9 and TDRD1.

93934:TMEM241
gene id: 93934:TMEM241
uniprot id: A0A8C2TDS2
names: Subcellular Location Annotation
messages: Membrane

93934:TCIRG1
gene id: 93934:TCIRG1
uniprot id: A0A8C2TSK7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

93934:EML4
gene id: 93934:EML4
uniprot id: A0A8C2T7Z9
uniprot id: A0A8C2T8L5
uniprot id: A0A8C2TAH7
uniprot id: A0A8C2TBS8
names: Similarity
messages: Belongs to the WD repeat EMAP family.

93934:FBLN1
gene id: 93934:FBLN1
uniprot id: A0A8C2TX73
uniprot id: A0A8C2U088
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fibulin family.
messages: Homomultimerizes and interacts with various extracellular matrix components.
messages: Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:NUDT19
gene id: 93934:NUDT19
uniprot id: A0A8C2TVN1
names: Similarity
messages: Belongs to the Nudix hydrolase family.

93934:FAM102A
gene id: 93934:FAM102A
uniprot id: A0A8C2U9S9
names: Similarity
messages: Belongs to the FAM102 family.

93934:AACS
gene id: 93934:AACS
uniprot id: A0A8C2UDR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Converts acetoacetate to acetoacetyl-CoA in the cytosol.
messages: cytosol

93934:GJD2
gene id: 93934:GJD2
uniprot id: A0A8C2U1P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A connexon is composed of a hexamer of connexins.
messages: Belongs to the connexin family.
messages: Cell membrane
messages: Membrane
messages: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
messages: gap junction

93934:VAX1
gene id: 93934:VAX1
uniprot id: A0A8C2YGX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMX homeobox family.
messages: Nucleus

93934:CAPN5
gene id: 93934:CAPN5
uniprot id: A0A8C2SXX6
names: Similarity
messages: Belongs to the peptidase C2 family.

93934:ACSS2
gene id: 93934:ACSS2
uniprot id: A0A8C2UC02
uniprot id: A0A8C2UCC0
uniprot id: A0A8C2UEL7
uniprot id: A0A8C2YHC9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:RPL23A
gene id: 93934:RPL23A
uniprot id: A0A8C2YBC5
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

93934:GBE1
gene id: 93934:GBE1
uniprot id: A0A8C2SSK4
uniprot id: A0A8C2SSR4
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

93934:RPS7
gene id: 93934:RPS7
uniprot id: A0A8C2T7W9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

93934:CSF3R
gene id: 93934:CSF3R
uniprot id: A0A8C2U246
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

93934:MRPL42
gene id: 93934:MRPL42
uniprot id: A0A8C2SYZ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL42 family.
messages: Mitochondrion

93934:ALCAM
gene id: 93934:ALCAM
uniprot id: A0A8C2YF59
names: Subcellular Location Annotation
messages: Cell membrane
messages: axon
messages: dendrite

93934:SLC9A9
gene id: 93934:SLC9A9
uniprot id: A0A8C2TKG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Endosome membrane
messages: Membrane

93934:BMP4
gene id: 93934:BMP4
uniprot id: A0A8C2TLT6
names: Similarity
messages: Belongs to the TGF-beta family.

93934:MKNK1
gene id: 93934:MKNK1
uniprot id: A0A8C2TEG1
uniprot id: A0A8C2YAC7
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PSMB3
gene id: 93934:PSMB3
uniprot id: A0A8C2STB7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus

93934:QRSL1
gene id: 93934:QRSL1
uniprot id: A0A8C2TAJ9
uniprot id: A0A8C2TG05
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatCAB amidotransferase (AdT) complex, composed of A (QRSL1), B (GATB) and C (GATC) subunits.

93934:FLI1
gene id: 93934:FLI1
uniprot id: A0A8C2T0E5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:LPAR1
gene id: 93934:LPAR1
uniprot id: A0A8C2SX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Cell surface
messages: Endosome
messages: Membrane

93934:LOC107319388
gene id: 93934:LOC107319388
uniprot id: A0A8C2TWK9
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

93934:PTTG1
gene id: 93934:PTTG1
uniprot id: A0A8C2TAZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

93934:DCP2
gene id: 93934:DCP2
uniprot id: A0A8C2TE80
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

93934:MARF1
gene id: 93934:MARF1
uniprot id: A0A8C2TF35
names: Subcellular Location Annotation
messages: Peroxisome

93934:LOC107321607
gene id: 93934:LOC107321607
uniprot id: A0A8C2U5V3
names: Subcellular Location Annotation
messages: Membrane

93934:ARRDC1
gene id: 93934:ARRDC1
uniprot id: A0A8C2YFC4
names: Similarity
messages: Belongs to the arrestin family.

93934:MED16
gene id: 93934:MED16
uniprot id: A0A8C2THH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 16 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

93934:AQP1
gene id: 93934:AQP1
uniprot id: A0A8C2TGZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Membrane

93934:BICD2
gene id: 93934:BICD2
uniprot id: A0A8C2TLV2
names: Similarity
messages: Belongs to the BicD family.

93934:LOC107318625
gene id: 93934:LOC107318625
uniprot id: A0A8C2T567
names: Similarity
messages: Belongs to the actin family.

93934:POLR2C
gene id: 93934:POLR2C
uniprot id: A0A8C2TLD3
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

93934:B3GALT2
gene id: 93934:B3GALT2
uniprot id: A0A8C2UFT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:MAP1LC3C
gene id: 93934:MAP1LC3C
uniprot id: A0A8C2TSW6
names: Similarity
messages: Belongs to the ATG8 family.

93934:SLC25A26
gene id: 93934:SLC25A26
uniprot id: A0A8C2U838
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:RPS6KA3
gene id: 93934:RPS6KA3
uniprot id: A0A8C2U3N8
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

93934:C1QA
gene id: 93934:C1QA
uniprot id: A0A8C2T5Q9
names: Function
messages: C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.

93934:LOC107312624
gene id: 93934:LOC107312624
uniprot id: A0A8C2TW19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UIF family.
messages: Nucleus speckle

93934:SPRY2
gene id: 93934:SPRY2
uniprot id: A0A8C2YGE7
names: Similarity
messages: Belongs to the sprouty family.

93934:GOLGA5
gene id: 93934:GOLGA5
uniprot id: A0A8C2SNP9
names: Function
names: Subcellular Location Annotation
messages: Golgi apparatus membrane
messages: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.
messages: Membrane

93934:MAB21L2
gene id: 93934:MAB21L2
uniprot id: A0A8C2Y7M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mab-21 family.
messages: Cytoplasm
messages: Nucleus

93934:UCN3
gene id: 93934:UCN3
uniprot id: A0A8C2Y6Q6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.
messages: Binds with high affinity to CRF receptors 2-alpha and 2-beta.
messages: Secreted
messages: Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.

93934:POLR1E
gene id: 93934:POLR1E
uniprot id: A0A8C2T3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

93934:LOC107325456
gene id: 93934:LOC107325456
uniprot id: A0A8C2YAQ9
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:GPR161
gene id: 93934:GPR161
uniprot id: A0A8C2U2U0
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:PDSS1
gene id: 93934:PDSS1
uniprot id: A0A8C2Y6M3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

93934:CPNE8
gene id: 93934:CPNE8
uniprot id: A0A8C2T6J6
names: Similarity
messages: Belongs to the copine family.

93934:UNC5C
gene id: 93934:UNC5C
uniprot id: A0A8C2T2J6
uniprot id: A0A8C2T3E2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

93934:ALG12
gene id: 93934:ALG12
uniprot id: A0A8C2Y946
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107319344
gene id: 93934:LOC107319344
uniprot id: A0A8C2TWD3
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

93934:PLXNB2
gene id: 93934:PLXNB2
uniprot id: A0A8C2TBW1
names: Caution
names: Similarity
messages: Belongs to the plexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:POLG
gene id: 93934:POLG
uniprot id: A0A8C2UB10
names: Function
names: Subcellular Location Annotation
messages: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.
messages: mitochondrion nucleoid

93934:UBE2T
gene id: 93934:UBE2T
uniprot id: A0A8C2Y9Q9
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:PWWP3A
gene id: 93934:PWWP3A
uniprot id: A0A8C2TGA2
names: Similarity
messages: Belongs to the PWWP3A family.

93934:UTP25
gene id: 93934:UTP25
uniprot id: A0A8C2T8E1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP25 family.
messages: nucleolus

93934:DBNDD1
gene id: 93934:DBNDD1
uniprot id: A0A8C2YDJ0
names: Similarity
messages: Belongs to the dysbindin family.

93934:MRPL20
gene id: 93934:MRPL20
uniprot id: A0A8C2TGL7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.

93934:RFFL
gene id: 93934:RFFL
uniprot id: A0A8C2TFY8
names: Subcellular Location Annotation
messages: Cell membrane

93934:SPCS3
gene id: 93934:SPCS3
uniprot id: A0A8C2TCF3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

93934:NADSYN1
gene id: 93934:NADSYN1
uniprot id: A0A8C2TS10
names: Similarity
names: Subunit
messages: Homohexamer.
messages: In the C-terminal section; belongs to the NAD synthetase family.

93934:TMTC1
gene id: 93934:TMTC1
uniprot id: A0A8C2UAM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMTC family.
messages: Endoplasmic reticulum
messages: Membrane

93934:LPGAT1
gene id: 93934:LPGAT1
uniprot id: A0A8C2T821
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:FGF16
gene id: 93934:FGF16
uniprot id: A0A8C2U199
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:ACKR3
gene id: 93934:ACKR3
uniprot id: A0A8C2TUA2
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:PCK1
gene id: 93934:PCK1
uniprot id: A0A8C2T4I0
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.

93934:GNAL
gene id: 93934:GNAL
uniprot id: A0A8C2Y8V1
uniprot id: A0A8C2Y912
names: Similarity
messages: Belongs to the G-alpha family. G(s) subfamily.

93934:KEF80 p07
gene id: 93934:KEF80_p07
uniprot id: A0A1D9CQS5
uniprot id: Q8SEW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

93934:TSPAN18
gene id: 93934:TSPAN18
uniprot id: A0A8C2THF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:CASC3
gene id: 93934:CASC3
uniprot id: A0A8C2STI9
uniprot id: A0A8C2Y5Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CASC3 family.
messages: Nucleus speckle
messages: dendrite
messages: perinuclear region

93934:LSM7
gene id: 93934:LSM7
uniprot id: A0A8C2Y7P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

93934:NRF1
gene id: 93934:NRF1
uniprot id: A0A8C2SNE1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRF1/Ewg family.
messages: Nucleus

93934:FAIM2
gene id: 93934:FAIM2
uniprot id: A0A8C2SWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93934:LOC107319389
gene id: 93934:LOC107319389
uniprot id: A0A8C2TS36
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

93934:LOC107320769
gene id: 93934:LOC107320769
uniprot id: A0A8C2SNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Cell membrane
messages: Membrane

93934:ADAM9
gene id: 93934:ADAM9
uniprot id: A0A8C2TWH5
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107313678
gene id: 93934:LOC107313678
uniprot id: A0A8C2T8E4
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:TAF13
gene id: 93934:TAF13
uniprot id: A0A8C2YF42
names: Subcellular Location Annotation
messages: Nucleus

93934:P3H2
gene id: 93934:P3H2
uniprot id: A0A8C2TPF9
names: Similarity
messages: Belongs to the leprecan family.

93934:SF3B4
gene id: 93934:SF3B4
uniprot id: A0A8C2TSM5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SF3B4 family.
messages: Nucleus

93934:BRINP3
gene id: 93934:BRINP3
uniprot id: A0A8C2UII4
names: Similarity
messages: Belongs to the BRINP family.

93934:ZFPM2
gene id: 93934:ZFPM2
uniprot id: A0A8C2SZH5
names: Subcellular Location Annotation
messages: Nucleus

93934:SULF2
gene id: 93934:SULF2
uniprot id: A0A8C2SN04
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfatase family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Cell surface
messages: Endoplasmic reticulum
messages: Golgi stack
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:NTN3
gene id: 93934:NTN3
uniprot id: A0A8C2YFQ7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:DCBLD2
gene id: 93934:DCBLD2
uniprot id: A0A8C2U3H0
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:OPN5
gene id: 93934:OPN5
uniprot id: D9N3D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:SEMA3E
gene id: 93934:SEMA3E
uniprot id: A0A8C2SX64
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107322632
gene id: 93934:LOC107322632
uniprot id: A0A8C2SVE2
names: Similarity
messages: Belongs to the peptidase C14A family.

93934:RAB3B
gene id: 93934:RAB3B
uniprot id: A0A8C2TI64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Protein transport. Probably involved in vesicular traffic.

93934:VIPR1
gene id: 93934:VIPR1
uniprot id: F5C1U0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

93934:TMCO1
gene id: 93934:TMCO1
uniprot id: A0A8C2UHI1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMCO1 family.
messages: Calcium-selective channel required to prevent calcium stores from overfilling.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:BPNT1
gene id: 93934:BPNT1
uniprot id: A0A8C2Y8J3
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93934:ETV5
gene id: 93934:ETV5
uniprot id: A0A8C2T1P0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:LOC107310133
gene id: 93934:LOC107310133
uniprot id: A0A8C2YA39
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:UGDH
gene id: 93934:UGDH
uniprot id: A0A8C2U292
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
messages: Homohexamer.
messages: Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

93934:MPV17L2
gene id: 93934:MPV17L2
uniprot id: A0A8C2TKS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

93934:ALDOB
gene id: 93934:ALDOB
uniprot id: A0A8C2SN11
names: Similarity
messages: Belongs to the class I fructose-bisphosphate aldolase family.

93934:TXNL4B
gene id: 93934:TXNL4B
uniprot id: A0A8C2U1L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Nucleus
messages: Plays role in pre-mRNA splicing.

93934:PIK3R2
gene id: 93934:PIK3R2
uniprot id: A0A8C2TLW0
names: Similarity
messages: Belongs to the PI3K p85 subunit family.

93934:SLC6A4
gene id: 93934:SLC6A4
uniprot id: A0A8C2TQH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A4 subfamily.
messages: Cell membrane
messages: Endomembrane system
messages: Endosome membrane
messages: Membrane
messages: Serotonin transporter whose primary function in the central nervous system involves the regulation of serotonergic signaling via transport of serotonin molecules from the synaptic cleft back into the pre-synaptic terminal for re-utilization. Plays a key role in mediating regulation of the availability of serotonin to other receptors of serotonergic systems. Terminates the action of serotonin and recycles it in a sodium-dependent manner.
messages: Synapse
messages: focal adhesion

93934:ST6GAL1
gene id: 93934:ST6GAL1
uniprot id: A0A8C2SZC0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:AGTR2
gene id: 93934:AGTR2
uniprot id: A0A8C2TUB9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MTUS1.
messages: Membrane

93934:MANF
gene id: 93934:MANF
uniprot id: A0A8C2TAR4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARMET family.
messages: Secreted

93934:CSF3
gene id: 93934:CSF3
uniprot id: A0A8C2SQD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IL-6 superfamily.
messages: Secreted

93934:TUBGCP6
gene id: 93934:TUBGCP6
uniprot id: A0A8C2TBM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: centrosome

93934:ASXL1
gene id: 93934:ASXL1
uniprot id: A0A8C2T0A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Asx family.
messages: Nucleus

93934:NAALADL2
gene id: 93934:NAALADL2
uniprot id: A0A8C2TR30
uniprot id: A0A8C2TRT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M28 family. M28B subfamily.
messages: Membrane

93934:TPD52
gene id: 93934:TPD52
uniprot id: A0A8C2YBG6
names: Similarity
messages: Belongs to the TPD52 family.

93934:FAM199X
gene id: 93934:FAM199X
uniprot id: A0A8C2YG07
names: Similarity
messages: Belongs to the FAM199 family.

93934:SLC7A5
gene id: 93934:SLC7A5
uniprot id: A0A8C2TSR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family.
messages: Membrane

93934:FABP3
gene id: 93934:FABP3
uniprot id: A0A8C2TXZ3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:LGI2
gene id: 93934:LGI2
uniprot id: A0A8C2U6M8
names: Subcellular Location Annotation
messages: Secreted

93934:SEC23A
gene id: 93934:SEC23A
uniprot id: A0A8C2U8M3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

93934:CD244
gene id: 93934:CD244
uniprot id: A0A8C2YCT0
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107316090
gene id: 93934:LOC107316090
uniprot id: A0A8C2UDI2
names: Subcellular Location Annotation
messages: Nucleus

93934:NKIRAS2
gene id: 93934:NKIRAS2
uniprot id: A0A8C2SY14
names: Similarity
messages: Belongs to the small GTPase superfamily. Ras family. KappaB-Ras subfamily.

93934:FUCA1
gene id: 93934:FUCA1
uniprot id: A0A8C2SXJ5
names: Function
names: Similarity
names: Subunit
messages: Alpha-L-fucosidase is responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins.
messages: Belongs to the glycosyl hydrolase 29 family.
messages: Homotetramer.

93934:GNG5
gene id: 93934:GNG5
uniprot id: A0A8C2Y944
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:GDE1
gene id: 93934:GDE1
uniprot id: A0A8C2TXT1
names: Similarity
messages: Belongs to the glycerophosphoryl diester phosphodiesterase family.

93934:LOC107306001
gene id: 93934:LOC107306001
uniprot id: A0A8C2U694
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:LOC107319525
gene id: 93934:LOC107319525
uniprot id: A0A8C2TTF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the p22phox family.
messages: Cell membrane
messages: Composed of a heavy chain (beta) and a light chain (alpha). Component of an NADPH oxidase complex composed of a heterodimer formed by the membrane proteins CYBA and CYBB and the cytosolic subunits NCF1, NCF2 and NCF4. Interacts with NCF1 (via SH3 domain).
messages: Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
messages: Membrane

93934:PDHB
gene id: 93934:PDHB
uniprot id: A0A8C2U2P0
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

93934:OLFM3
gene id: 93934:OLFM3
uniprot id: A0A8C2UHS8
uniprot id: A0A8C2UJP8
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse

93934:LOC107320762
gene id: 93934:LOC107320762
uniprot id: A0A8C2Y4K7
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:TMOD4
gene id: 93934:TMOD4
uniprot id: A0A8C2TUC6
names: Subcellular Location Annotation
messages: cytoskeleton

93934:AGTPBP1
gene id: 93934:AGTPBP1
uniprot id: A0A8C2TDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: cytosol

93934:RPS6KA6
gene id: 93934:RPS6KA6
uniprot id: A0A8C2TXS9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.

93934:DNASE2B
gene id: 93934:DNASE2B
uniprot id: A0A8C2T7W3
names: Similarity
messages: Belongs to the DNase II family.

93934:NDUFS6
gene id: 93934:NDUFS6
uniprot id: A0A8C2TVU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFS6 subunit family.
messages: Mitochondrion inner membrane

93934:DLST
gene id: 93934:DLST
uniprot id: A0A8C2U9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Mitochondrion matrix

93934:COQ2
gene id: 93934:COQ2
uniprot id: A0A8C2TCS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

93934:ARPC1A
gene id: 93934:ARPC1A
uniprot id: A0A8C2SN92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: Nucleus
messages: cytoskeleton

93934:ZRANB2
gene id: 93934:ZRANB2
uniprot id: A0A8C2TWY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZRANB2 family.
messages: May interfere with constitutive 5'-splice site selection.
messages: Nucleus

93934:FAM214A
gene id: 93934:FAM214A
uniprot id: A0A8C2YEL3
names: Similarity
messages: Belongs to the FAM214 family.

93934:TSNAX
gene id: 93934:TSNAX
uniprot id: A0A8C2SX11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the translin family.
messages: Nucleus

93934:GLO1
gene id: 93934:GLO1
uniprot id: A0A8C2TDL2
names: Function
names: Similarity
messages: Belongs to the glyoxalase I family.
messages: Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.

93934:FZD7
gene id: 93934:FZD7
uniprot id: A0A8C2TXJ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor Fz/Smo family.
messages: Cell membrane
messages: Endosome membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:ADCK2
gene id: 93934:ADCK2
uniprot id: A0A8C2UD03
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

93934:EGR3
gene id: 93934:EGR3
uniprot id: A0A8C2YDH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EGR C2H2-type zinc-finger protein family.
messages: Nucleus

93934:MAP3K7
gene id: 93934:MAP3K7
uniprot id: A0A8C2ST68
uniprot id: A0A8C2Y5U1
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

93934:MAP2K2
gene id: 93934:MAP2K2
uniprot id: A0A8C2TFX0
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PPP1R15B
gene id: 93934:PPP1R15B
uniprot id: A0A8C2TBF9
names: Similarity
messages: Belongs to the PPP1R15 family.

93934:ATP5F1B
gene id: 93934:ATP5F1B
uniprot id: A0A8C2Y714
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

93934:DIP2B
gene id: 93934:DIP2B
uniprot id: A0A8C2YGL8
names: Similarity
messages: Belongs to the DIP2 family.

93934:ADAMTS2
gene id: 93934:ADAMTS2
uniprot id: A0A8C2T1I2
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:RPA2
gene id: 93934:RPA2
uniprot id: A0A8C2U001
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

93934:LOC107313493
gene id: 93934:LOC107313493
uniprot id: A0A8C2SPG5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:LOC107313570
gene id: 93934:LOC107313570
uniprot id: A0A8C2STM2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

93934:ZDHHC3
gene id: 93934:ZDHHC3
uniprot id: A0A8C2SZM9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:SPTLC2
gene id: 93934:SPTLC2
uniprot id: A0A8C2UBE8
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

93934:PTH
gene id: 93934:PTH
uniprot id: A0A8C2U713
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the parathyroid hormone family.
messages: PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion.
messages: Secreted

93934:GALNT7
gene id: 93934:GALNT7
uniprot id: A0A8C2TC01
uniprot id: A0A8C2THC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:MIF
gene id: 93934:MIF
uniprot id: A0A8C2TAG0
names: Similarity
messages: Belongs to the MIF family.

93934:PPP2R5E
gene id: 93934:PPP2R5E
uniprot id: A0A8C2SXX7
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

93934:VPS41
gene id: 93934:VPS41
uniprot id: A0A8C2T475
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Early endosome membrane
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane
messages: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways.
messages: Vesicle
messages: clathrin-coated vesicle
messages: trans-Golgi network

93934:MAF
gene id: 93934:MAF
uniprot id: A0A8C2TT79
names: Similarity
messages: Belongs to the bZIP family. Maf subfamily.

93934:AREG
gene id: 93934:AREG
uniprot id: A0A8C2TC53
uniprot id: A0A8C2TEK4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:GDAP1
gene id: 93934:GDAP1
uniprot id: A0A8C2TK89
names: Similarity
messages: Belongs to the GST superfamily.

93934:COPS5
gene id: 93934:COPS5
uniprot id: A0A8C2YB77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M67A family. CSN5 subfamily.
messages: synaptic vesicle

93934:DDX17
gene id: 93934:DDX17
uniprot id: A0A8C2TRD4
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:LOC107315891
gene id: 93934:LOC107315891
uniprot id: A0A8C2YAW1
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

93934:NXPH1
gene id: 93934:NXPH1
uniprot id: A0A8C2TKR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

93934:TDRD7
gene id: 93934:TDRD7
uniprot id: A0A8C2Y694
names: Subcellular Location Annotation
messages: Cytoplasm

93934:XKR8
gene id: 93934:XKR8
uniprot id: A0A8C2TVT8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:HMGB3
gene id: 93934:HMGB3
uniprot id: A0A8C2SLG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

93934:SLC26A2
gene id: 93934:SLC26A2
uniprot id: A0A8C2Y9D7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sulfate transporter. May play a role in endochondral bone formation.

93934:MTMR7
gene id: 93934:MTMR7
uniprot id: A0A8C2TH68
uniprot id: A0A8C2YAJ1
uniprot id: A0A8C2YAP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cytoplasm

93934:MDH2
gene id: 93934:MDH2
uniprot id: A0A8C2TH69
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

93934:MVB12B
gene id: 93934:MVB12B
uniprot id: A0A8C2TFS4
uniprot id: A0A8C2TKP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MVB12 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

93934:SASS6
gene id: 93934:SASS6
uniprot id: A0A8C2UKS8
names: Subcellular Location Annotation
messages: centrosome

93934:IGFBP5
gene id: 93934:IGFBP5
uniprot id: A0A8C2YC61
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:RAB3GAP1
gene id: 93934:RAB3GAP1
uniprot id: A0A8C2UB87
uniprot id: A0A8C2UBJ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rab3-GAP catalytic subunit family.
messages: Cytoplasm

93934:GNG7
gene id: 93934:GNG7
uniprot id: A0A8C2TFH2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G protein gamma family.
messages: Cell membrane
messages: G proteins are composed of 3 units; alpha, beta and gamma.
messages: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.

93934:IPO11
gene id: 93934:IPO11
uniprot id: A0A8C2ST57
names: Subcellular Location Annotation
messages: Cytoplasm

93934:SNAPC3
gene id: 93934:SNAPC3
uniprot id: A0A8C2T0N6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNAPC3/SRD2 family.
messages: Nucleus
messages: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1.
messages: Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.

93934:SRP72
gene id: 93934:SRP72
uniprot id: A0A8C2TI11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

93934:TACR3
gene id: 93934:TACR3
uniprot id: A0A8C2TDP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:STON1
gene id: 93934:STON1
uniprot id: A0A8C2SN15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Stoned B family.
messages: Cytoplasm
messages: May be involved in the endocytic machinery.

93934:NLGN1
gene id: 93934:NLGN1
uniprot id: A0A8C2TQP1
uniprot id: A0A8C2TUB0
uniprot id: A0A8C2YD22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

93934:LOC107306431
gene id: 93934:LOC107306431
uniprot id: A0A8C2TMI9
names: Similarity
messages: Belongs to the NipSnap family.

93934:PPP1R12A
gene id: 93934:PPP1R12A
uniprot id: A0A8C2TX88
uniprot id: A0A8C2TZN6
uniprot id: A0A8C2U0C6
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: PP1 comprises a catalytic subunit, and one or several targeting or regulatory subunits.

93934:SLA
gene id: 93934:SLA
uniprot id: A0A8C2TGG2
names: Subcellular Location Annotation
messages: Cytoplasm

93934:ATP11C
gene id: 93934:ATP11C
uniprot id: A0A8C2U0Z8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:JAG1
gene id: 93934:JAG1
uniprot id: A0A8C2SPQ3
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

93934:GRIA1
gene id: 93934:GRIA1
uniprot id: A0A8C2T713
uniprot id: A0A8C2T8N4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:ACTA2
gene id: 93934:ACTA2
uniprot id: A0A8C2YG26
names: Similarity
messages: Belongs to the actin family.

93934:STK32B
gene id: 93934:STK32B
uniprot id: A0A8C2UA24
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:PLA2G12A
gene id: 93934:PLA2G12A
uniprot id: A0A8C2T5C4
names: Subcellular Location Annotation
messages: Secreted

93934:VGLL4
gene id: 93934:VGLL4
uniprot id: A0A8C2YC12
names: Function
names: Similarity
messages: Belongs to the vestigial family.
messages: May act as a specific coactivator for the mammalian TEFs.

93934:ECHDC1
gene id: 93934:ECHDC1
uniprot id: A0A8C2T9P0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93934:C11H16orf70
gene id: 93934:C11H16orf70
uniprot id: A0A8C2SQT2
names: Similarity
messages: Belongs to the PHAF1 family.

93934:LOC107313414
gene id: 93934:LOC107313414
uniprot id: A0A8C2TJK6
names: Similarity
messages: Belongs to the pancreatic ribonuclease family.

93934:TENT5A
gene id: 93934:TENT5A
uniprot id: A0A8C2SVH1
uniprot id: A0A8C2SXG0
names: Similarity
messages: Belongs to the TENT family.

93934:OSBPL2
gene id: 93934:OSBPL2
uniprot id: A0A8C2SUM6
names: Similarity
messages: Belongs to the OSBP family.

93934:CDK3
gene id: 93934:CDK3
uniprot id: A0A8C2UEL4
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:DOCK1
gene id: 93934:DOCK1
uniprot id: A0A8C2SS00
names: Similarity
messages: Belongs to the DOCK family.

93934:LMX1A
gene id: 93934:LMX1A
uniprot id: A0A8C2YHV8
names: Subcellular Location Annotation
messages: Nucleus

93934:CARMIL1
gene id: 93934:CARMIL1
uniprot id: A0A8C2T347
uniprot id: A0A8C2T456
uniprot id: A0A8C2T583
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CARMIL family.
messages: Cytoplasm

93934:NKX2-8
gene id: 93934:NKX2-8
uniprot id: A0A8C2U8Z7
names: Subcellular Location Annotation
messages: Nucleus

93934:PLOD1
gene id: 93934:PLOD1
uniprot id: A0A8C2T3G0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane

93934:RHBDF1
gene id: 93934:RHBDF1
uniprot id: A0A8C2TX56
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S54 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

93934:GPR37
gene id: 93934:GPR37
uniprot id: A0A8C2YBJ4
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93934:C6
gene id: 93934:C6
uniprot id: A0A8C2TFF9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complement C6/C7/C8/C9 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:YWHAQ
gene id: 93934:YWHAQ
uniprot id: A0A8C2TFK5
names: Similarity
messages: Belongs to the 14-3-3 family.

93934:CLN5
gene id: 93934:CLN5
uniprot id: A0A8C2U8A6
names: Similarity
messages: Belongs to the CLN5 family.

93934:NEUROD1
gene id: 93934:NEUROD1
uniprot id: A0A8C2TZ11
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:DLX4
gene id: 93934:DLX4
uniprot id: A0A8C2UCN3
names: Subcellular Location Annotation
messages: Nucleus

93934:TNFRSF11B
gene id: 93934:TNFRSF11B
uniprot id: A0A8C2SYW7
uniprot id: A0A8C2SZI3
names: Caution
names: Function
names: Subunit
messages: Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:TMBIM4
gene id: 93934:TMBIM4
uniprot id: A0A8C2YDY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93934:FAM126B
gene id: 93934:FAM126B
uniprot id: A0A8C2TU97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAM126 family.
messages: Cell membrane
messages: Membrane
messages: cytosol

93934:NRXN1
gene id: 93934:NRXN1
uniprot id: A0A8C2SQ93
names: Caution
names: Similarity
messages: Belongs to the neurexin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ADHFE1
gene id: 93934:ADHFE1
uniprot id: A0A8C2YB73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the iron-containing alcohol dehydrogenase family. Hydroxyacid-oxoacid transhydrogenase subfamily.
messages: Mitochondrion

93934:YKT6
gene id: 93934:YKT6
uniprot id: A0A8C2TKJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cytoplasmic vesicle membrane
messages: Golgi apparatus membrane
messages: Membrane
messages: Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

93934:GPAM
gene id: 93934:GPAM
uniprot id: A0A8C2UFC2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPAT/DAPAT family.
messages: Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipids biosynthesis such as triglycerides, phosphatidic acids and lysophosphatidic acids.
messages: Mitochondrion outer membrane

93934:AXIN1
gene id: 93934:AXIN1
uniprot id: A0A8C2TXX5
names: Subcellular Location Annotation
messages: Cell membrane
messages: Cytoplasm
messages: Membrane
messages: Nucleus

93934:MRPS33
gene id: 93934:MRPS33
uniprot id: A0A8C2UG32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

93934:SMAD5
gene id: 93934:SMAD5
uniprot id: A0A8C2T1A4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:LOC107325888
gene id: 93934:LOC107325888
uniprot id: A0A8C2SWI6
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane
messages: Target cell membrane

93934:LOC107318485
gene id: 93934:LOC107318485
uniprot id: A0A8C2Y546
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DUOXA family.
messages: Membrane

93934:LOC107315905
gene id: 93934:LOC107315905
uniprot id: A0A8C2UB31
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

93934:GNB1
gene id: 93934:GNB1
uniprot id: A0A8C2TCY9
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

93934:NDUFA13
gene id: 93934:NDUFA13
uniprot id: A0A8C2TIY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I NDUFA13 subunit family.
messages: Complex I functions in the transfer of electrons from NADH to the respiratory chain. Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.
messages: Mitochondrion inner membrane

93934:NDRG3
gene id: 93934:NDRG3
uniprot id: A0A8C2UAY3
names: Similarity
messages: Belongs to the NDRG family.

93934:CPQ
gene id: 93934:CPQ
uniprot id: A0A8C2Y531
names: Subcellular Location Annotation
names: Subunit
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. The monomeric form is inactive while the homodimer is active.
messages: Lysosome
messages: Secreted

93934:PSMD12
gene id: 93934:PSMD12
uniprot id: A0A8C2UK06
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

93934:SNRPF
gene id: 93934:SNRPF
uniprot id: A0A8C2SX93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

93934:VIPR2
gene id: 93934:VIPR2
uniprot id: A0A8C2Y5Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family.
messages: Cell membrane
messages: Membrane

93934:SLC12A5
gene id: 93934:SLC12A5
uniprot id: A0A8C2T3T2
uniprot id: A0A8C2T3Z7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC12A transporter family.
messages: Membrane

93934:CPSF3
gene id: 93934:CPSF3
uniprot id: A0A8C2TFM1
names: Subcellular Location Annotation
messages: Nucleus

93934:SMARCAL1
gene id: 93934:SMARCAL1
uniprot id: A0A8C2TMG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily.
messages: Nucleus

93934:CD28
gene id: 93934:CD28
uniprot id: A0A8C2TU28
names: Subcellular Location Annotation
messages: Membrane

93934:NFKB1
gene id: 93934:NFKB1
uniprot id: A0A8C2Y8F0
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:PRKAA1
gene id: 93934:PRKAA1
uniprot id: A0A8C2T8U2
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.

93934:LOC107321417
gene id: 93934:LOC107321417
uniprot id: A0A8C2TN83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

93934:VPS54
gene id: 93934:VPS54
uniprot id: A0A8C2THS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS54 family.
messages: trans-Golgi network

93934:FADS2
gene id: 93934:FADS2
uniprot id: A0A8C2U4F7
names: Similarity
messages: Belongs to the fatty acid desaturase type 1 family.

93934:TXNRD1
gene id: 93934:TXNRD1
uniprot id: A0A8C2U9D3
names: Cofactor
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.

93934:CLCN4
gene id: 93934:CLCN4
uniprot id: A0A8C2U3V7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

93934:PRCP
gene id: 93934:PRCP
uniprot id: A0A8C2SUX1
names: Similarity
messages: Belongs to the peptidase S28 family.

93934:ANKRD34C
gene id: 93934:ANKRD34C
uniprot id: A0A8C2UGD1
names: Similarity
messages: Belongs to the ANKRD34 family.

93934:IARS1
gene id: 93934:IARS1
uniprot id: A0A8C2TK12
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:HSP90AB1
gene id: 93934:HSP90AB1
uniprot id: A0A8C2TFU3
uniprot id: C7G493
names: Similarity
messages: Belongs to the heat shock protein 90 family.

93934:CRHBP
gene id: 93934:CRHBP
uniprot id: A0A8C2T9N7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CRF-binding protein family.
messages: Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy.
messages: Secreted

93934:HMGB2
gene id: 93934:HMGB2
uniprot id: A0A8C2TC52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMGB family.
messages: Chromosome

93934:LOC107324716
gene id: 93934:LOC107324716
uniprot id: A0A8C2TB51
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:PPP6R3
gene id: 93934:PPP6R3
uniprot id: A0A8C2U6U6
names: Similarity
messages: Belongs to the SAPS family.

93934:COLGALT2
gene id: 93934:COLGALT2
uniprot id: A0A8C2UEN5
names: Similarity
messages: Belongs to the glycosyltransferase 25 family.

93934:ARHGEF9
gene id: 93934:ARHGEF9
uniprot id: A0A8C2U3A4
uniprot id: A0A8C2U4F1
uniprot id: A0A8C2YES2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Acts as guanine nucleotide exchange factor (GEF) for CDC42. Promotes formation of GPHN clusters.
messages: Cytoplasm
messages: Interacts with GPHN.
messages: Postsynaptic density

93934:SLC30A9
gene id: 93934:SLC30A9
uniprot id: A0A8C2U2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Cytoplasmic vesicle
messages: Endoplasmic reticulum
messages: Membrane
messages: Nucleus
messages: Vesicle

93934:AIF1L
gene id: 93934:AIF1L
uniprot id: A0A8C2SVY9
names: Subcellular Location Annotation
messages: ruffle membrane

93934:DCSTAMP
gene id: 93934:DCSTAMP
uniprot id: A0A8C2SNP3
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107314042
gene id: 93934:LOC107314042
uniprot id: A0A8C2SLZ0
names: Subcellular Location Annotation
messages: Secreted

93934:ITIH2
gene id: 93934:ITIH2
uniprot id: A0A8C2SV12
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITIH family.
messages: Secreted

93934:FAM149A
gene id: 93934:FAM149A
uniprot id: A0A8C2Y8H5
names: Similarity
messages: Belongs to the FAM149 family.

93934:PDCD10
gene id: 93934:PDCD10
uniprot id: A0A8C2U2Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDCD10 family.
messages: Cell membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

93934:DOLK
gene id: 93934:DOLK
uniprot id: A0A8C2UF50
names: Similarity
messages: Belongs to the polyprenol kinase family.

93934:LOC107313502
gene id: 93934:LOC107313502
uniprot id: A0A8C2SP76
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the intercrine alpha (chemokine CxC) family.
messages: Homodimer.
messages: Secreted

93934:CHRNA3
gene id: 93934:CHRNA3
uniprot id: A0A8C2Y8X7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:LOC107316709
gene id: 93934:LOC107316709
uniprot id: A0A8C2YFC0
names: Subcellular Location Annotation
names: Subunit
messages: Apical cell membrane
messages: Cell membrane
messages: Homodimer.
messages: Membrane

93934:IGFBP2
gene id: 93934:IGFBP2
uniprot id: A0A8C2TPN8
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:LOC107317915
gene id: 93934:LOC107317915
uniprot id: A0A8C2SPD7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aquaporins facilitate the transport of water and small neutral solutes across cell membranes.
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family. AQP11/AQP12 subfamily.
messages: Membrane

93934:IFNGR1
gene id: 93934:IFNGR1
uniprot id: A0A8C2TE19
names: Similarity
messages: Belongs to the type II cytokine receptor family.

93934:THBD
gene id: 93934:THBD
uniprot id: A0A8C2TW33
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:FOXK1
gene id: 93934:FOXK1
uniprot id: A0A8C2SPJ4
names: Subcellular Location Annotation
messages: Nucleus

93934:NME5
gene id: 93934:NME5
uniprot id: A0A8C2SZZ0
names: Similarity
messages: Belongs to the NDK family.

93934:GALC
gene id: 93934:GALC
uniprot id: A0A8C2SLQ3
uniprot id: A0A8C2SML1
names: Similarity
messages: Belongs to the glycosyl hydrolase 59 family.

93934:SERINC1
gene id: 93934:SERINC1
uniprot id: A0A8C2T9V0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

93934:DIS3
gene id: 93934:DIS3
uniprot id: A0A8C2UBV1
names: Similarity
messages: Belongs to the RNR ribonuclease family.

93934:STARD3NL
gene id: 93934:STARD3NL
uniprot id: A0A8C2TVU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

93934:CCR7
gene id: 93934:CCR7
uniprot id: A0A8C2SZF7
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:VPS37A
gene id: 93934:VPS37A
uniprot id: A0A8C2TJ66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS37 family.
messages: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
messages: Endosome membrane
messages: Late endosome membrane

93934:HS6ST1
gene id: 93934:HS6ST1
uniprot id: A0A8C2TSB6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate.
messages: Belongs to the sulfotransferase 6 family.
messages: Membrane

93934:LOC107324341
gene id: 93934:LOC107324341
uniprot id: A0A8C2TUZ1
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SPTSSA
gene id: 93934:SPTSSA
uniprot id: A0A8C2U342
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:GUCY1A1
gene id: 93934:GUCY1A1
uniprot id: A0A8C2SME8
uniprot id: A0A8C2SNB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Cytoplasm

93934:NME8
gene id: 93934:NME8
uniprot id: A0A8C2TVS4
names: Similarity
messages: Belongs to the NDK family.

93934:CAPRIN1
gene id: 93934:CAPRIN1
uniprot id: A0A8C2TV56
names: Similarity
messages: Belongs to the caprin family.

93934:PAQR7
gene id: 93934:PAQR7
uniprot id: A0A8C2U0W3
uniprot id: E7FM04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

93934:PTPRM
gene id: 93934:PTPRM
uniprot id: A0A8C2T7D3
uniprot id: A0A8C2T7N9
uniprot id: A0A8C2TB40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Receptor class 2B subfamily.
messages: Membrane

93934:ABI3
gene id: 93934:ABI3
uniprot id: A0A8C2UCR4
names: Similarity
messages: Belongs to the ABI family.

93934:SMC3
gene id: 93934:SMC3
uniprot id: A0A8C2UC51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex also plays an important role in spindle pole assembly during mitosis and in chromosomes movement.
messages: Nucleus
messages: centromere

93934:FSCN1
gene id: 93934:FSCN1
uniprot id: A0A8C2Y4Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fascin family.
messages: cytoskeleton

93934:DLGAP3
gene id: 93934:DLGAP3
uniprot id: A0A8C2U0C2
names: Similarity
messages: Belongs to the SAPAP family.

93934:IL4R
gene id: 93934:IL4R
uniprot id: A0A8C2YAC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Membrane
messages: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.

93934:TMPRSS6
gene id: 93934:TMPRSS6
uniprot id: A0A8C2TNT0
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:KLHL22
gene id: 93934:KLHL22
uniprot id: A0A8C2T8Y6
names: Subcellular Location Annotation
messages: Lysosome
messages: Nucleus
messages: centrosome
messages: cytosol
messages: spindle

93934:ADAMTS17
gene id: 93934:ADAMTS17
uniprot id: A0A8C2UGG7
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:IP6K2
gene id: 93934:IP6K2
uniprot id: A0A8C2YCQ7
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

93934:HADH
gene id: 93934:HADH
uniprot id: A0A8C2TBB3
names: Similarity
messages: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.

93934:TTC39B
gene id: 93934:TTC39B
uniprot id: A0A8C2T525
names: Similarity
messages: Belongs to the TTC39 family.

93934:B3GNT9
gene id: 93934:B3GNT9
uniprot id: A0A8C2Y4W4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 31 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:HTR6
gene id: 93934:HTR6
uniprot id: A0A8C2U736
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CCNC
gene id: 93934:CCNC
uniprot id: A0A8C2TDA0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.
messages: Nucleus

93934:PAM
gene id: 93934:PAM
uniprot id: A0A8C2TGR3
uniprot id: A0A8C2Y9Y4
uniprot id: A0A8C2YA38
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the peptidyl-alpha-hydroxyglycine alpha-amidating lyase family.
messages: In the N-terminal section; belongs to the copper type II ascorbate-dependent monooxygenase family.
messages: Membrane
messages: secretory vesicle membrane

93934:KCNJ15
gene id: 93934:KCNJ15
uniprot id: A0A8C2T7X1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

93934:TTC21B
gene id: 93934:TTC21B
uniprot id: A0A8C2YHJ9
names: Similarity
messages: Belongs to the TTC21 family.

93934:CZH18orf32
gene id: 93934:CZH18orf32
uniprot id: A0A8C2Y701
names: Similarity
messages: Belongs to the UPF0729 family.

93934:RPF2
gene id: 93934:RPF2
uniprot id: A0A8C2TBN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

93934:LOC107319292
gene id: 93934:LOC107319292
uniprot id: A0A8C2TUU7
names: Similarity
messages: Belongs to the type-B carboxylesterase/lipase family.

93934:LOC107316661
gene id: 93934:LOC107316661
uniprot id: A0A8C2SVU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

93934:CHUK
gene id: 93934:CHUK
uniprot id: A0A8C2TQU7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:WASHC5
gene id: 93934:WASHC5
uniprot id: A0A8C2T236
names: Similarity
messages: Belongs to the strumpellin family.

93934:DGKG
gene id: 93934:DGKG
uniprot id: A0A8C2SZQ7
names: Similarity
messages: Belongs to the eukaryotic diacylglycerol kinase family.

93934:GIPC3
gene id: 93934:GIPC3
uniprot id: A0A8C2T167
uniprot id: A0A8C2T3F8
names: Similarity
messages: Belongs to the GIPC family.

93934:SLC35C1
gene id: 93934:SLC35C1
uniprot id: A0A8C2TRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TPT transporter family. SLC35C subfamily.
messages: Membrane

93934:SSR2
gene id: 93934:SSR2
uniprot id: A0A8C2YDI5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP-beta family.
messages: Endoplasmic reticulum membrane
messages: Heterotetramer of TRAP-alpha, TRAP-beta, TRAP-delta and TRAP-gamma.
messages: Membrane
messages: TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

93934:PHOX2B
gene id: 93934:PHOX2B
uniprot id: A0A8C2U4N1
names: Subcellular Location Annotation
messages: Nucleus

93934:ALG2
gene id: 93934:ALG2
uniprot id: A0A8C2T5F7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.
messages: Membrane

93934:INHBB
gene id: 93934:INHBB
uniprot id: A0A8C2TP73
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TGF-beta family.
messages: Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
messages: Secreted

93934:EHHADH
gene id: 93934:EHHADH
uniprot id: A0A8C2U709
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

93934:EIF4E2
gene id: 93934:EIF4E2
uniprot id: A0A8C2YCL0
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.

93934:RSPO2
gene id: 93934:RSPO2
uniprot id: A0A8C2T0M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the R-spondin family.
messages: Secreted

93934:TM4SF4
gene id: 93934:TM4SF4
uniprot id: A0A8C2U568
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

93934:NMUR1
gene id: 93934:NMUR1
uniprot id: A0A8C2YCK6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for the neuromedin-U and neuromedin-S neuropeptides.

93934:ATPAF2
gene id: 93934:ATPAF2
uniprot id: A0A8C2SQS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

93934:ELAVL1
gene id: 93934:ELAVL1
uniprot id: A0A8C2T2P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM elav family.
messages: Cytoplasm

93934:DENND10
gene id: 93934:DENND10
uniprot id: A0A8C2UC64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DENND10 family.
messages: Endosome
messages: Late endosome

93934:GPM6A
gene id: 93934:GPM6A
uniprot id: A0A8C2TC28
uniprot id: A0A8C2THF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

93934:SEC61A2
gene id: 93934:SEC61A2
uniprot id: A0A8C2Y6Q3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:TDRKH
gene id: 93934:TDRKH
uniprot id: A0A8C2SMX3
names: Subcellular Location Annotation
messages: Cytoplasm

93934:SIGIRR
gene id: 93934:SIGIRR
uniprot id: A0A8C2TRE9
names: Similarity
messages: Belongs to the interleukin-1 receptor family.

93934:PCLO
gene id: 93934:PCLO
uniprot id: A0A8C2SZ30
uniprot id: A0A8C2Y793
names: Subcellular Location Annotation
messages: Presynaptic active zone

93934:NPBWR2
gene id: 93934:NPBWR2
uniprot id: A0A8C2SVH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:SOX14
gene id: 93934:SOX14
uniprot id: A0A8C2U6Q2
names: Subcellular Location Annotation
messages: Nucleus

93934:COG8
gene id: 93934:COG8
uniprot id: A0A8C2TY57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COG8 family.
messages: Component of the conserved oligomeric Golgi complex which is composed of eight different subunits and is required for normal Golgi morphology and localization.
messages: Golgi apparatus membrane
messages: Membrane

93934:MTO1
gene id: 93934:MTO1
uniprot id: A0A8C2T2V1
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

93934:TM9SF2
gene id: 93934:TM9SF2
uniprot id: A0A8C2TZH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

93934:LOC107316810
gene id: 93934:LOC107316810
uniprot id: A0A8C2UHV4
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CCN2
gene id: 93934:CCN2
uniprot id: A0A8C2Y9F7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCN family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted

93934:ERLIN2
gene id: 93934:ERLIN2
uniprot id: A0A8C2TY15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the band 7/mec-2 family.
messages: Membrane

93934:GPM6B
gene id: 93934:GPM6B
uniprot id: A0A8C2U737
uniprot id: A0A8C2YFK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myelin proteolipid protein family.
messages: Membrane

93934:SORBS2
gene id: 93934:SORBS2
uniprot id: A0A8C2T5G7
names: Subcellular Location Annotation
messages: focal adhesion

93934:ADAMTS5
gene id: 93934:ADAMTS5
uniprot id: A0A8C2SWH3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:AFG3L2
gene id: 93934:AFG3L2
uniprot id: A0A8C2TB14
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

93934:DPAGT1
gene id: 93934:DPAGT1
uniprot id: A0A8C2SXR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ZNF622
gene id: 93934:ZNF622
uniprot id: A0A8C2TZ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the REI1 family.
messages: Cytoplasm

93934:FAM102B
gene id: 93934:FAM102B
uniprot id: A0A8C2YHL8
names: Similarity
messages: Belongs to the FAM102 family.

93934:LOC107319845
gene id: 93934:LOC107319845
uniprot id: A0A8C2YCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

93934:SLC19A1
gene id: 93934:SLC19A1
uniprot id: A0A8C2YC31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Basolateral cell membrane
messages: Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family.
messages: Cell membrane
messages: Transporter that mediates the import of reduced folates.

93934:FLCN
gene id: 93934:FLCN
uniprot id: A0A8C2SNI3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the folliculin family.
messages: Lysosome membrane
messages: Membrane
messages: Nucleus
messages: centrosome
messages: cilium
messages: cytosol
messages: spindle

93934:ARSJ
gene id: 93934:ARSJ
uniprot id: A0A8C2SVG5
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:SUCLG2
gene id: 93934:SUCLG2
uniprot id: A0A8C2U4U9
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family. GTP-specific subunit beta subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
messages: Heterodimer of an alpha and a beta subunit. The beta subunit determines specificity for GTP.
messages: Mitochondrion

93934:NPL
gene id: 93934:NPL
uniprot id: A0A8C2UK17
names: Similarity
names: Subunit
messages: Belongs to the DapA family.
messages: Homotetramer.

93934:PKP2
gene id: 93934:PKP2
uniprot id: A0A8C2UE71
names: Similarity
messages: Belongs to the beta-catenin family.

93934:MYO1F
gene id: 93934:MYO1F
uniprot id: A0A8C2TC31
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:SRP54
gene id: 93934:SRP54
uniprot id: A0A8C2U3F7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of a signal recognition particle (SRP) complex that consists of a 7SL RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Nucleus speckle
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

93934:HDAC3
gene id: 93934:HDAC3
uniprot id: A0A8C2TK18
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
messages: Nucleus

93934:MAP3K14
gene id: 93934:MAP3K14
uniprot id: A0A8C2U6Y5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.
messages: Cytoplasm
messages: Lymphotoxin beta-activated kinase which seems to be exclusively involved in the activation of NF-kappa-B and its transcriptional activity.

93934:RTN1
gene id: 93934:RTN1
uniprot id: A0A8C2T2G5
uniprot id: A0A8C2T3Y6
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:HTT
gene id: 93934:HTT
uniprot id: A0A8C2UC36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the huntingtin family.
messages: Cytoplasm
messages: May play a role in microtubule-mediated transport or vesicle function.
messages: Nucleus

93934:PROM1
gene id: 93934:PROM1
uniprot id: A0A8C2U4H9
uniprot id: A0A8C2U7Q9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prominin family.
messages: Membrane
messages: microvillus membrane

93934:SLC5A7
gene id: 93934:SLC5A7
uniprot id: A0A8C2TQ91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93934:EMX2
gene id: 93934:EMX2
uniprot id: A0A8C2UDP8
names: Subcellular Location Annotation
messages: Nucleus

93934:ETS1
gene id: 93934:ETS1
uniprot id: A0A8C2T0D4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Cytoplasm
messages: Nucleus

93934:AKAP1
gene id: 93934:AKAP1
uniprot id: A0A8C2U6W4
names: Subcellular Location Annotation
messages: Cytoplasm

93934:GPR39
gene id: 93934:GPR39
uniprot id: A9XG45
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:NMT2
gene id: 93934:NMT2
uniprot id: A0A8C2T225
names: Function
names: Similarity
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.

93934:GSG1
gene id: 93934:GSG1
uniprot id: A0A8C2TA08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSG1 family.
messages: Membrane

93934:STRN3
gene id: 93934:STRN3
uniprot id: A0A8C2U5C4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

93934:KEF80 p11
gene id: 93934:KEF80_p11
uniprot id: A0A1D9CQR4
uniprot id: P24984
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Binds 2 heme A groups non-covalently per subunit.
messages: Binds a copper B center.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)) (By similarity). As a newly synthesized protein, rapidly incorporates into a multi-subunit assembly intermediate in the inner membrane, called MITRAC (mitochondrial translation regulation assembly intermediate of cytochrome c oxidase) complex, whose core components are COA3/MITRAC12 and COX14. Within the MITRAC complex, interacts with COA3 and with SMIM20/MITRAC7; the interaction with SMIM20 stabilizes the newly synthesized MT-CO1 and prevents its premature turnover. Interacts with TMEM177 in a COX20-dependent manner (By similarity).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

93934:SLCO2A1
gene id: 93934:SLCO2A1
uniprot id: A0A8C2SPL8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:NPY1R
gene id: 93934:NPY1R
uniprot id: A0A8C2SQP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:FMOD
gene id: 93934:FMOD
uniprot id: A0A8C2U9P1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis.
messages: Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
messages: Binds to type I and type II collagen.
messages: extracellular matrix

93934:YPEL1
gene id: 93934:YPEL1
uniprot id: A0A8C2UBS5
names: Similarity
messages: Belongs to the yippee family.

93934:CNKSR1
gene id: 93934:CNKSR1
uniprot id: A0A8C2TUD1
names: Similarity
messages: Belongs to the CNKSR family.

93934:FUT11
gene id: 93934:FUT11
uniprot id: A0A8C2TWI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 10 family.
messages: Golgi stack membrane
messages: Probable fucosyltransferase.

93934:TPI1
gene id: 93934:TPI1
uniprot id: A0A8C2TZ82
names: Function
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.
messages: It is also responsible for the non-negligible production of methylglyoxal a reactive cytotoxic side-product that modifies and can alter proteins, DNA and lipids.
messages: Triosephosphate isomerase is an extremely efficient metabolic enzyme that catalyzes the interconversion between dihydroxyacetone phosphate (DHAP) and D-glyceraldehyde-3-phosphate (G3P) in glycolysis and gluconeogenesis.

93934:CEBPA
gene id: 93934:CEBPA
uniprot id: A0A8C2TX92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. C/EBP subfamily.
messages: Nucleus

93934:INTS8
gene id: 93934:INTS8
uniprot id: A0A8C2SP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Integrator subunit 8 family.
messages: Nucleus

93934:LOC107321618
gene id: 93934:LOC107321618
uniprot id: A0A8C2U685
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:ACVR1
gene id: 93934:ACVR1
uniprot id: A0A8C2UFZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
messages: Membrane

93934:TLR4
gene id: 93934:TLR4
uniprot id: A0A8C2UEM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Toll-like receptor family.
messages: Membrane

93934:SNW1
gene id: 93934:SNW1
uniprot id: A0A8C2YGD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SNW family.
messages: Identified in the spliceosome C complex.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

93934:UCHL1
gene id: 93934:UCHL1
uniprot id: A0A8C2U003
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C12 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:KATNAL2
gene id: 93934:KATNAL2
uniprot id: A0A8C2SYB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily. A-like 2 sub-subfamily.
messages: Cytoplasm
messages: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays.
messages: cytoskeleton
messages: spindle
messages: spindle pole

93934:FAM122B
gene id: 93934:FAM122B
uniprot id: A0A8C2U0T6
names: Similarity
messages: Belongs to the FAM122 family.

93934:SLC39A9
gene id: 93934:SLC39A9
uniprot id: A0A8C2TVH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: May act as a zinc-influx transporter.
messages: Membrane

93934:SEC22A
gene id: 93934:SEC22A
uniprot id: A0A8C2UD69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: May be involved in vesicle transport between the ER and the Golgi complex.
messages: Membrane

93934:NR3C2
gene id: 93934:NR3C2
uniprot id: A0A8C2Y5S1
names: Subcellular Location Annotation
messages: Nucleus

93934:SEC24D
gene id: 93934:SEC24D
uniprot id: A0A8C2SVA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

93934:CSRP1
gene id: 93934:CSRP1
uniprot id: P67967
names: Domain
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Glycine-rich repeats mediate the association with the actin cytoskeleton.
messages: Heat stable protein, that interacts with zyxin/ZYX. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
messages: Interacts with ZYX.
messages: Nucleus
messages: cytoskeleton

93934:CDS2
gene id: 93934:CDS2
uniprot id: A0A8C2YBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Catalyzes the conversion of phosphatidic acid (PA) to CDP-diacylglycerol (CDP-DAG), an essential intermediate in the synthesis of phosphatidylglycerol, cardiolipin and phosphatidylinositol.
messages: Membrane

93934:OXSM
gene id: 93934:OXSM
uniprot id: A0A8C2TL32
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

93934:TYW3
gene id: 93934:TYW3
uniprot id: A0A8C2TU98
names: Function
names: Similarity
messages: Belongs to the TYW3 family.
messages: Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.

93934:IFT20
gene id: 93934:IFT20
uniprot id: A0A8C2U8W9
names: Subcellular Location Annotation
messages: centriole
messages: cilium
messages: cis-Golgi network

93934:KRR1
gene id: 93934:KRR1
uniprot id: A0A8C2TXY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
messages: nucleolus

93934:RRP15
gene id: 93934:RRP15
uniprot id: A0A8C2T632
names: Similarity
messages: Belongs to the RRP15 family.

93934:ANAPC4
gene id: 93934:ANAPC4
uniprot id: A0A8C2U7M1
names: Function
names: Similarity
messages: Belongs to the APC4 family.
messages: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

93934:SPC25
gene id: 93934:SPC25
uniprot id: A0A8C2U7Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

93934:SORCS3
gene id: 93934:SORCS3
uniprot id: A0A8C2UBS2
names: Similarity
messages: Belongs to the VPS10-related sortilin family. SORCS subfamily.

93934:SH3RF1
gene id: 93934:SH3RF1
uniprot id: A0A8C2SM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SH3RF family.
messages: lamellipodium
messages: perinuclear region
messages: trans-Golgi network

93934:PRKAA2
gene id: 93934:PRKAA2
uniprot id: A0A8C2TMY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily.
messages: Cytoplasm

93934:LOC107308547
gene id: 93934:LOC107308547
uniprot id: A0A8C2Y7G1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family.
messages: Endoplasmic reticulum

93934:CREG1
gene id: 93934:CREG1
uniprot id: A0A8C2SRN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CREG family.
messages: Secreted

93934:PPM1A
gene id: 93934:PPM1A
uniprot id: A0A8C2SZ92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PP2C family.
messages: Membrane
messages: cytosol

93934:THEMIS
gene id: 93934:THEMIS
uniprot id: A0A8C2Y9K2
names: Similarity
messages: Belongs to the themis family.

93934:CCT3
gene id: 93934:CCT3
uniprot id: A0A8C2TPW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

93934:UTP3
gene id: 93934:UTP3
uniprot id: A0A8C2Y5A3
names: Similarity
messages: Belongs to the SAS10 family.

93934:LOC107324058
gene id: 93934:LOC107324058
uniprot id: A0A8C2TC02
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:POC5
gene id: 93934:POC5
uniprot id: A0A8C2SQR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POC5 family.
messages: Essential for the assembly of the distal half of centrioles, required for centriole elongation.
messages: centriole

93934:HSPB1
gene id: 93934:HSPB1
uniprot id: A0A8C2TET1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: spindle

93934:LOC107321557
gene id: 93934:LOC107321557
uniprot id: A0A8C2U0H1
names: Subcellular Location Annotation
messages: Secreted
messages: Synapse
messages: axon
messages: dendrite

93934:FGF20
gene id: 93934:FGF20
uniprot id: A0A8C2TG25
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:LOC107324492
gene id: 93934:LOC107324492
uniprot id: A0A8C2TQY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:ADGRD1
gene id: 93934:ADGRD1
uniprot id: A0A8C2YGJ0
uniprot id: A0A8C2YGK9
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:C13H5orf24
gene id: 93934:C13H5orf24
uniprot id: A0A8C2SYW3
names: Similarity
messages: Belongs to the UPF0461 family.

93934:MINAR1
gene id: 93934:MINAR1
uniprot id: A0A8C2UBD3
names: Similarity
messages: Belongs to the MINAR family.

93934:IDS
gene id: 93934:IDS
uniprot id: A0A8C2SKC7
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:STK38
gene id: 93934:STK38
uniprot id: A0A8C2Y9W6
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:TNS4
gene id: 93934:TNS4
uniprot id: A0A8C2SW08
names: Similarity
messages: Belongs to the PTEN phosphatase protein family.

93934:CDK5R1
gene id: 93934:CDK5R1
uniprot id: A0A8C2U693
names: Similarity
names: Subunit
messages: Belongs to the cyclin-dependent kinase 5 activator family.
messages: Heterodimer of a catalytic subunit and a regulatory subunit.

93934:SMAD3
gene id: 93934:SMAD3
uniprot id: A0A8C2UHM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dwarfin/SMAD family.
messages: Cytoplasm
messages: Nucleus

93934:BGLAP
gene id: 93934:BGLAP
uniprot id: A0A8C2T988
names: Similarity
messages: Belongs to the osteocalcin/matrix Gla protein family.

93934:LOC107317594
gene id: 93934:LOC107317594
uniprot id: A0A8C2TCS2
names: Similarity
messages: Belongs to the amidase family.

93934:EIF3A
gene id: 93934:EIF3A
uniprot id: A0A8C2YGW5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit A family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

93934:CTLA4
gene id: 93934:CTLA4
uniprot id: A0A8C2TYQ4
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
messages: Membrane

93934:PRTFDC1
gene id: 93934:PRTFDC1
uniprot id: A0A8C2SXF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

93934:LOC107305989
gene id: 93934:LOC107305989
uniprot id: A0A8C2YFL1
names: PTM
names: Similarity
messages: Belongs to the sulfatase family.
messages: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.

93934:ADA
gene id: 93934:ADA
uniprot id: A0A8C2Y4Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
messages: Cell junction
messages: Cell membrane
messages: Cytoplasmic vesicle lumen

93934:SBK1
gene id: 93934:SBK1
uniprot id: A0A8C2U200
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
messages: Cytoplasm

93934:LOC107315954
gene id: 93934:LOC107315954
uniprot id: A0A8C2YGH9
names: Subcellular Location Annotation
messages: Nucleus

93934:FOXN3
gene id: 93934:FOXN3
uniprot id: A0A8C2SNH9
names: Subcellular Location Annotation
messages: Nucleus

93934:PIGM
gene id: 93934:PIGM
uniprot id: A0A8C2YCT1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

93934:GPR182
gene id: 93934:GPR182
uniprot id: A0A8C2Y708
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:GPR34
gene id: 93934:GPR34
uniprot id: A0A8C2YBV1
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:CFAP298
gene id: 93934:CFAP298
uniprot id: A0A8C2SZQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CFAP298 family.
messages: cilium basal body

93934:CAMSAP2
gene id: 93934:CAMSAP2
uniprot id: A0A8C2UJ71
names: Domain
names: Similarity
messages: Belongs to the CAMSAP1 family.
messages: The CKK domain binds microtubules.

93934:PCYT1B
gene id: 93934:PCYT1B
uniprot id: A0A8C2U0N6
uniprot id: A0A8C2U5Y8
names: Function
names: Similarity
messages: Belongs to the cytidylyltransferase family.
messages: Catalyzes the key rate-limiting step in the CDP-choline pathway for phosphatidylcholine biosynthesis.

93934:LOC107312387
gene id: 93934:LOC107312387
uniprot id: A0A8C2Y977
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:SMARCAD1
gene id: 93934:SMARCAD1
uniprot id: A0A8C2TB07
uniprot id: A0A8C2TEK3
names: Subcellular Location Annotation
messages: Chromosome

93934:PARN
gene id: 93934:PARN
uniprot id: A0A8C2TR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Cytoplasm
messages: Nucleus

93934:SLC2A8
gene id: 93934:SLC2A8
uniprot id: A0A8C2YAV2
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

93934:TMEM167A
gene id: 93934:TMEM167A
uniprot id: A0A8C2SQN1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:STC2
gene id: 93934:STC2
uniprot id: A0A8C2TBQ0
names: Similarity
names: Subunit
messages: Belongs to the stanniocalcin family.
messages: Homodimer; disulfide-linked.

93934:GSX2
gene id: 93934:GSX2
uniprot id: A0A8C2TGZ7
names: Subcellular Location Annotation
messages: Nucleus

93934:PEMT
gene id: 93934:PEMT
uniprot id: A0A8C2SPT3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the three sequential steps of the methylation pathway for the biosynthesis of phosphatidylcholine, a critical and essential component for membrane structure. Uses S-adenosylmethionine (S-adenosyl-L-methionine, SAM or AdoMet) as the methyl group donor for the methylation of phosphatidylethanolamine (1,2-diacyl-sn-glycero-3-phosphoethanolamine, PE) to phosphatidylmonomethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N-methylethanolamine, PMME), PMME to phosphatidyldimethylethanolamine (1,2-diacyl-sn-glycero-3-phospho-N,N-dimethylethanolamine, PDME), and PDME to phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine, PC), producing S-adenosyl-L-homocysteine in each step.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Mitochondrion membrane

93934:CHST9
gene id: 93934:CHST9
uniprot id: A0A8C2TDT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 2 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:LOC107313383
gene id: 93934:LOC107313383
uniprot id: A0A8C2Y5L3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

93934:NCLN
gene id: 93934:NCLN
uniprot id: A0A8C2TE17
names: Function
names: Similarity
messages: Belongs to the nicastrin family.
messages: May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning.

93934:YAE1
gene id: 93934:YAE1
uniprot id: A0A8C2T0V2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:LOC107312691
gene id: 93934:LOC107312691
uniprot id: A0A8C2TXP8
names: Similarity
messages: Belongs to the FAM122 family.

93934:CMTM4
gene id: 93934:CMTM4
uniprot id: A0A8C2TSG9
names: Subcellular Location Annotation
messages: Membrane

93934:DCT
gene id: 93934:DCT
uniprot id: A0A8C2YGG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosinase family.
messages: Melanosome membrane
messages: Membrane

93934:TEKT2
gene id: 93934:TEKT2
uniprot id: A0A8C2YET5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tektin family.
messages: flagellum

93934:PACC1
gene id: 93934:PACC1
uniprot id: A0A8C2Y8J8
uniprot id: A0A8C2Y8Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proton-activated chloride channel family.
messages: Cell membrane
messages: Membrane

93934:CBFB
gene id: 93934:CBFB
uniprot id: A0A8C2SNW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF-beta family.
messages: Nucleus

93934:HIKESHI
gene id: 93934:HIKESHI
uniprot id: A0A8C2SYW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.
messages: Belongs to the OPI10 family.
messages: Cytoplasm
messages: Forms an asymmetric homodimer; required for binding and nuclear import of HSP70 proteins. Interacts with ATP-bound HSP70 proteins.
messages: Nucleus
messages: cytosol

93934:PJVK
gene id: 93934:PJVK
uniprot id: A0A8C2YF03
names: Similarity
messages: Belongs to the gasdermin family.

93934:DDX52
gene id: 93934:DDX52
uniprot id: A0A8C2YFV4
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.

93934:NDST4
gene id: 93934:NDST4
uniprot id: A0A8C2SWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. NDST subfamily.
messages: Membrane

93934:PACSIN2
gene id: 93934:PACSIN2
uniprot id: A0A8C2TX71
uniprot id: A0A8C2YDU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PACSIN family.
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Early endosome
messages: Endosome membrane
messages: Membrane
messages: Recycling endosome membrane
messages: caveola
messages: cytoskeleton
messages: ruffle membrane

93934:GLMP
gene id: 93934:GLMP
uniprot id: A0A8C2TQ64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLMP family.
messages: Lysosome membrane
messages: Required to protect lysosomal transporter MFSD1 from lysosomal proteolysis and for MFSD1 lysosomal localization.

93934:FBLN5
gene id: 93934:FBLN5
uniprot id: A0A8C2Y5I0
names: Caution
names: Similarity
messages: Belongs to the fibulin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ING5
gene id: 93934:ING5
uniprot id: A0A8C2SRM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

93934:NAT10
gene id: 93934:NAT10
uniprot id: A0A8C2TV62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with THUMPD1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

93934:DOK5
gene id: 93934:DOK5
uniprot id: A0A8C2T5Q8
uniprot id: A0A8C2Y8L3
names: Similarity
messages: Belongs to the DOK family. Type B subfamily.

93934:RBL2
gene id: 93934:RBL2
uniprot id: A0A8C2TNL2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the retinoblastoma protein (RB) family.
messages: Nucleus

93934:DPYSL4
gene id: 93934:DPYSL4
uniprot id: A0A8C2SY32
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

93934:LOC107312401
gene id: 93934:LOC107312401
uniprot id: A0A8C2Y9D5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:CNOT8
gene id: 93934:CNOT8
uniprot id: A0A8C2T3D5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

93934:DSEL
gene id: 93934:DSEL
uniprot id: A0A8C2T717
names: Similarity
messages: Belongs to the dermatan-sulfate isomerase family.

93934:PRKACB
gene id: 93934:PRKACB
uniprot id: A0A8C2T7J0
uniprot id: A0A8C2T9P1
uniprot id: A0A8C2TB02
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.

93934:LOC107323285
gene id: 93934:LOC107323285
uniprot id: A0A8C2TEM7
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

93934:TDO2
gene id: 93934:TDO2
uniprot id: A0A8C2SL86
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tryptophan 2,3-dioxygenase family.
messages: Binds 1 heme group per subunit.
messages: Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L-tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
messages: Homotetramer. Dimer of dimers.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107314887
gene id: 93934:LOC107314887
uniprot id: A0A8C2YH37
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

93934:BDKRB2
gene id: 93934:BDKRB2
uniprot id: A0A8C2SSS9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Forms a complex with PECAM1 and GNAQ. Interacts with PECAM1.
messages: Membrane
messages: Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.

93934:NSG2
gene id: 93934:NSG2
uniprot id: A0A8C2TAY9
names: Similarity
messages: Belongs to the NSG family.

93934:SENP6
gene id: 93934:SENP6
uniprot id: A0A8C2T535
uniprot id: A0A8C2Y8E7
names: Similarity
messages: Belongs to the peptidase C48 family.

93934:EXOG
gene id: 93934:EXOG
uniprot id: A0A8C2TIM1
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

93934:NUP93
gene id: 93934:NUP93
uniprot id: A0A8C2Y6L0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin interacting component (NIC) family.
messages: Nucleus membrane
messages: Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance.
messages: nuclear pore complex

93934:RORA
gene id: 93934:RORA
uniprot id: A0A8C2TNA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:ICOS
gene id: 93934:ICOS
uniprot id: A0A8C2TXK6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.
messages: Homodimer; disulfide-linked.
messages: Membrane

93934:NEIL1
gene id: 93934:NEIL1
uniprot id: A0A8C2T7V6
names: Similarity
messages: Belongs to the FPG family.

93934:SNX9
gene id: 93934:SNX9
uniprot id: A0A8C2TB50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Cytoplasmic vesicle membrane

93934:GTF2A1
gene id: 93934:GTF2A1
uniprot id: A0A8C2UD34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

93934:FAM189A2
gene id: 93934:FAM189A2
uniprot id: A0A8C2T772
names: Similarity
messages: Belongs to the ENTREP family.

93934:LOC107309566
gene id: 93934:LOC107309566
uniprot id: A0A8C2U060
names: Similarity
messages: Belongs to the serpin family. Ov-serpin subfamily.

93934:SLC4A11
gene id: 93934:SLC4A11
uniprot id: A0A8C2TA59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

93934:LOC107319837
gene id: 93934:LOC107319837
uniprot id: A0A8C2YE54
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107314846
gene id: 93934:LOC107314846
uniprot id: A0A8C2TVS1
names: Domain
names: Subcellular Location Annotation
messages: The N-terminal C2 domain associates with lipid membranes upon calcium binding.
messages: cytosol

93934:LOC107323355
gene id: 93934:LOC107323355
uniprot id: A0A8C2SQC5
names: Similarity
messages: Belongs to the 'GDXG' lipolytic enzyme family.

93934:PPP2R5A
gene id: 93934:PPP2R5A
uniprot id: A0A8C2T9L2
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B56 family.

93934:TBX5
gene id: 93934:TBX5
uniprot id: A0A8C2TZM5
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:ZFX
gene id: 93934:ZFX
uniprot id: A0A8C2U0S0
uniprot id: A0A8C2U326
names: Subcellular Location Annotation
messages: Nucleus

93934:JAK2
gene id: 93934:JAK2
uniprot id: A0A8C2Y685
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. JAK subfamily.
messages: Endomembrane system
messages: Nucleus

93934:DYNLRB2
gene id: 93934:DYNLRB2
uniprot id: A0A8C2TSL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules.
messages: Belongs to the GAMAD family.
messages: cytoskeleton

93934:PEBP1
gene id: 93934:PEBP1
uniprot id: A0A8C2TUL0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

93934:COPB1
gene id: 93934:COPB1
uniprot id: A0A8C2SYG3
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

93934:FANCC
gene id: 93934:FANCC
uniprot id: A0A8C2TAS6
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the multisubunit FA complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM. This complex may also include HSP70.
messages: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1.
messages: Nucleus

93934:TRMT13
gene id: 93934:TRMT13
uniprot id: A0A8C2UIN0
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

93934:ST13
gene id: 93934:ST13
uniprot id: A0A8C2Y9X1
names: Similarity
messages: Belongs to the FAM10 family.

93934:ZDHHC7
gene id: 93934:ZDHHC7
uniprot id: A0A8C2TSP2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:IL2RB
gene id: 93934:IL2RB
uniprot id: A0A8C2TTZ3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type I cytokine receptor family. Type 4 subfamily.
messages: Cell membrane
messages: Membrane
messages: Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit. Interacts with SHB upon interleukin stimulation.

93934:SLC15A4
gene id: 93934:SLC15A4
uniprot id: A0A8C2UDZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

93934:LOC107321660
gene id: 93934:LOC107321660
uniprot id: A0A8C2U0W2
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

93934:ATP6V1D
gene id: 93934:ATP6V1D
uniprot id: A0A8C2U0K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase D subunit family.
messages: clathrin-coated vesicle membrane

93934:HDAC9
gene id: 93934:HDAC9
uniprot id: A0A8C2TJ07
uniprot id: A0A8C2TKY7
uniprot id: A0A8C2TLY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

93934:MLLT11
gene id: 93934:MLLT11
uniprot id: A0A8C2YDN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MLLT11 family.
messages: Nucleus
messages: centrosome

93934:FGD4
gene id: 93934:FGD4
uniprot id: A0A8C2UAN7
names: Subcellular Location Annotation
messages: cytoskeleton

93934:DIPK1C
gene id: 93934:DIPK1C
uniprot id: A0A8C2T7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIPK family.
messages: Endoplasmic reticulum membrane

93934:LOC107312406
gene id: 93934:LOC107312406
uniprot id: A0A8C2T7E3
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:PRKCD
gene id: 93934:PRKCD
uniprot id: A0A8C2SVK3
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression.
messages: Cytoplasm
messages: Interacts with PDPK1 (via N-terminal region), RAD9A, CDCP1, MUC1 and VASP.
messages: Novel PKCs (PRKCD, PRKCE, PRKCH and PRKCQ) are calcium-insensitive, but activated by diacylglycerol (DAG) and phosphatidylserine.
messages: Nucleus
messages: perinuclear region

93934:UBE2H
gene id: 93934:UBE2H
uniprot id: A0A8C2SL45
uniprot id: A0A8C2SL52
uniprot id: A0A8C2SLA6
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:ADGRA1
gene id: 93934:ADGRA1
uniprot id: A0A8C2U7Q6
uniprot id: A0A8C2UAE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily.
messages: Membrane

93934:SLCO4A1
gene id: 93934:SLCO4A1
uniprot id: A0A8C2SRN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Membrane

93934:PNRC1
gene id: 93934:PNRC1
uniprot id: A0A8C2SVV5
names: Subcellular Location Annotation
messages: Nucleus

93934:YOD1
gene id: 93934:YOD1
uniprot id: A0A8C2TWQ3
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and participates in endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by triming the ubiquitin chain on the associated substrate to facilitate their threading through the VCP/p97 pore. Cleaves both polyubiquitin and di-ubiquitin.

93934:B4GALT7
gene id: 93934:B4GALT7
uniprot id: A0A8C2Y9H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

93934:CCNB2
gene id: 93934:CCNB2
uniprot id: A0A8C2TNF4
names: Similarity
messages: Belongs to the cyclin family.

93934:PTPN21
gene id: 93934:PTPN21
uniprot id: A0A8C2SKE9
uniprot id: A0A8C2SLS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

93934:GPD2
gene id: 93934:GPD2
uniprot id: A0A8C2UH34
names: Function
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Calcium-responsive mitochondrial glycerol-3-phosphate dehydrogenase which seems to be a key component of the pancreatic beta-cell glucose-sensing device.

93934:E2F1
gene id: 93934:E2F1
uniprot id: A0A8C2UHR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the E2F/DP family.
messages: Nucleus

93934:TBX4
gene id: 93934:TBX4
uniprot id: A0A8C2U197
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:SAMD4A
gene id: 93934:SAMD4A
uniprot id: A0A8C2Y7Z9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMAUG family.
messages: Cytoplasm

93934:LOC107316140
gene id: 93934:LOC107316140
uniprot id: A0A8C2UEC6
names: Similarity
messages: Belongs to the ARTD/PARP family.

93934:SLC6A14
gene id: 93934:SLC6A14
uniprot id: A0A8C2TTP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
messages: Membrane

93934:MEF2D
gene id: 93934:MEF2D
uniprot id: A0A8C2TU15
names: Subcellular Location Annotation
messages: Nucleus

93934:POSTN
gene id: 93934:POSTN
uniprot id: A0A8C2U8Z4
uniprot id: A0A8C2U9C4
uniprot id: A0A8C2UBL5
uniprot id: A0A8C2UCT5
uniprot id: A0A8C2UDG4
uniprot id: A0A8C2UEL2
names: Subcellular Location Annotation
messages: extracellular matrix

93934:CMC1
gene id: 93934:CMC1
uniprot id: A0A8C2TLS5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion

93934:DNAL4
gene id: 93934:DNAL4
uniprot id: A0A8C2TQK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light chain family.
messages: cytoskeleton

93934:PDE5A
gene id: 93934:PDE5A
uniprot id: A0A8C2SUN4
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:YIPF4
gene id: 93934:YIPF4
uniprot id: A0A8C2TMP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Membrane

93934:DDX54
gene id: 93934:DDX54
uniprot id: A0A8C2TRP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.
messages: nucleolus

93934:GFRAL
gene id: 93934:GFRAL
uniprot id: A0A8C2Y8Y9
names: Similarity
messages: Belongs to the GDNFR family.

93934:TBXT
gene id: 93934:TBXT
uniprot id: A0A8C2SWK6
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:POU3F2
gene id: 93934:POU3F2
uniprot id: Q9PVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family. Class-3 subfamily.
messages: Nucleus

93934:LOC107309133
gene id: 93934:LOC107309133
uniprot id: A0A8C2TMR6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:CEP57
gene id: 93934:CEP57
uniprot id: A0A8C2STV8
names: Similarity
messages: Belongs to the translokin family.

93934:PRKAB1
gene id: 93934:PRKAB1
uniprot id: A0A8C2TS55
names: Function
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.
messages: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).

93934:NLGN4X
gene id: 93934:NLGN4X
uniprot id: A0A8C2U775
uniprot id: A0A8C2U8N4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type-B carboxylesterase/lipase family.
messages: Cell membrane
messages: Membrane

93934:INPP5A
gene id: 93934:INPP5A
uniprot id: A0A8C2SWP9
uniprot id: A0A8C2SZ43
uniprot id: A0A8C2Y6J7
names: Similarity
messages: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family.

93934:MKS1
gene id: 93934:MKS1
uniprot id: A0A8C2SYN6
names: Subcellular Location Annotation
messages: cilium basal body

93934:ESR1
gene id: 93934:ESR1
uniprot id: Q8AYH0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR3 subfamily.
messages: Binds DNA as a homodimer.
messages: Nucleus
messages: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.

93934:AGPAT4
gene id: 93934:AGPAT4
uniprot id: A0A8C2SVM2
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

93934:DIS3L2
gene id: 93934:DIS3L2
uniprot id: A0A8C2TPV2
uniprot id: A0A8C2TSH1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation.
messages: Belongs to the RNR ribonuclease family. DIS3L2 subfamily.
messages: Cytoplasm
messages: P-body
messages: Specifically recognizes and binds polyuridylated RNAs via 3 RNA-binding regions (named U-zone 1, U-zone 2 and U-zone 3) that form an open funnel on one face of the catalytic domain, allowing RNA to navigate a path to the active site.

93934:SLC25A13
gene id: 93934:SLC25A13
uniprot id: A0A8C2TH92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

93934:LOC107323279
gene id: 93934:LOC107323279
uniprot id: A0A8C2T8E9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:DUSP8
gene id: 93934:DUSP8
uniprot id: A0A8C2YFS1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

93934:ATP6V1C2
gene id: 93934:ATP6V1C2
uniprot id: A0A8C2TJ27
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex. The V1 complex consists of three catalytic AB heterodimers that form a heterohexamer, three peripheral stalks each consisting of EG heterodimers, one central rotor including subunits D and F, and the regulatory subunits C and H. The proton translocation complex V0 consists of the proton transport subunit a, a ring of proteolipid subunits c9c'', rotary subunit d, subunits e and f, and two accessory subunits.

93934:LSM3
gene id: 93934:LSM3
uniprot id: A0A8C2U025
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

93934:GORASP2
gene id: 93934:GORASP2
uniprot id: A0A8C2U542
names: Similarity
messages: Belongs to the GORASP family.

93934:REV1
gene id: 93934:REV1
uniprot id: A0A8C2SMT4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

93934:NAGA
gene id: 93934:NAGA
uniprot id: A0A8C2T9J7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 27 family.
messages: Homodimer.
messages: Lysosome

93934:IP6K3
gene id: 93934:IP6K3
uniprot id: A0A8C2YFF3
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

93934:PSMG2
gene id: 93934:PSMG2
uniprot id: A0A8C2T7P5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1.
messages: Forms a heterodimer with PSMG1.

93934:EIF6
gene id: 93934:EIF6
uniprot id: A0A8C2UH83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: nucleolus

93934:NEU3
gene id: 93934:NEU3
uniprot id: A0A8C2T1F0
names: Similarity
messages: Belongs to the glycosyl hydrolase 33 family.

93934:UCK1
gene id: 93934:UCK1
uniprot id: A0A8C2Y7I9
names: Similarity
messages: Belongs to the uridine kinase family.

93934:SPATA6
gene id: 93934:SPATA6
uniprot id: A0A8C2TGA0
names: Similarity
messages: Belongs to the SPATA6 family.

93934:BCL2L13
gene id: 93934:BCL2L13
uniprot id: A0A8C2U5U6
names: Similarity
messages: Belongs to the Bcl-2 family.

93934:CENPM
gene id: 93934:CENPM
uniprot id: A0A8C2TCG0
names: Subcellular Location Annotation
messages: Nucleus

93934:LOC107321023
gene id: 93934:LOC107321023
uniprot id: A0A8C2YFR6
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:HTR1D
gene id: 93934:HTR1D
uniprot id: A0A8C2TZ96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:ESYT2
gene id: 93934:ESYT2
uniprot id: A0A8C2SS39
uniprot id: A0A8C2SU77
uniprot id: A0A8C2SVC0
uniprot id: A0A8C2Y5Z5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the extended synaptotagmin family.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:ACTR8
gene id: 93934:ACTR8
uniprot id: A0A8C2TPT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the actin family. ARP8 subfamily.
messages: Chromosome
messages: Component of the chromatin remodeling INO80 complex; specifically part of a complex module associated with the DBINO domain of INO80. Exists as monomers and dimers, but the dimer is most probably the biologically relevant form required for stable interactions with histones that exploits the twofold symmetry of the nucleosome core.
messages: Nucleus
messages: Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.
messages: Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair.

93934:TMEM59
gene id: 93934:TMEM59
uniprot id: A0A8C2TMR3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM59 family.
messages: Golgi apparatus membrane
messages: Membrane

93934:QKI
gene id: 93934:QKI
uniprot id: A0A8C2SVG2
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

93934:TMEM183A
gene id: 93934:TMEM183A
uniprot id: A0A8C2T8F5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM183 family.
messages: Membrane

93934:GRIN2B
gene id: 93934:GRIN2B
uniprot id: A0A8C2TBY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
messages: Synaptic cell membrane

93934:ADRB2
gene id: 93934:ADRB2
uniprot id: A0A8C2T8K1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:TF
gene id: 93934:TF
uniprot id: A0A8C2SMS1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferrin family.
messages: Monomer.
messages: Secreted

93934:OSBPL8
gene id: 93934:OSBPL8
uniprot id: A0A8C2TWN9
uniprot id: A0A8C2TZ59
uniprot id: A0A8C2TZI2
uniprot id: A0A8C2U098
uniprot id: A0A8C2U221
names: Similarity
messages: Belongs to the OSBP family.

93934:ISX
gene id: 93934:ISX
uniprot id: A0A8C2U715
names: Subcellular Location Annotation
messages: Nucleus

93934:RAB32
gene id: 93934:RAB32
uniprot id: A0A8C2SZF2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Membrane
messages: The small GTPases Rab are key regulators in vesicle trafficking.

93934:SF3B6
gene id: 93934:SF3B6
uniprot id: A0A8C2TK44
names: Subcellular Location Annotation
messages: Nucleus

93934:CTSL
gene id: 93934:CTSL
uniprot id: A0A8C2TDL6
names: Similarity
messages: Belongs to the peptidase C1 family.

93934:APOA4
gene id: 93934:APOA4
uniprot id: A0A8C2TIV7
names: Similarity
messages: Belongs to the apolipoprotein A1/A4/E family.

93934:CAVIN1
gene id: 93934:CAVIN1
uniprot id: A0A8C2Y6Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAVIN family.
messages: caveola

93934:STARD13
gene id: 93934:STARD13
uniprot id: A0A8C2UCY0
uniprot id: A0A8C2UEX2
uniprot id: A0A8C2YGR9
names: Subcellular Location Annotation
messages: Cytoplasm

93934:ADSS1
gene id: 93934:ADSS1
uniprot id: A0A8C2SRG8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

93934:TSN
gene id: 93934:TSN
uniprot id: A0A8C2SNH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the translin family.
messages: DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots.
messages: Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand.
messages: Nucleus
messages: Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.

93934:PHACTR4
gene id: 93934:PHACTR4
uniprot id: A0A8C2TXT5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatase and actin regulator family.
messages: Binds PPP1CA and actin.
messages: Cytoplasm
messages: Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to repression of the integrin signaling through the rho/rock pathway.
messages: lamellipodium

93934:ATP8A1
gene id: 93934:ATP8A1
uniprot id: A0A8C2TZP8
uniprot id: A0A8C2U170
uniprot id: A0A8C2U3F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:HIBADH
gene id: 93934:HIBADH
uniprot id: A0A8C2TQA3
names: Similarity
messages: Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.

93934:LIFR
gene id: 93934:LIFR
uniprot id: A0A8C2T6H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type I cytokine receptor family. Type 2 subfamily.
messages: Membrane

93934:GCLC
gene id: 93934:GCLC
uniprot id: A0A8C2T5Z0
uniprot id: A0A8C2T9F2
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

93934:PKN2
gene id: 93934:PKN2
uniprot id: A0A8C2T7M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
messages: Cleavage furrow
messages: Midbody
messages: Nucleus

93934:LOC107316671
gene id: 93934:LOC107316671
uniprot id: A0A8C2ST20
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the organo anion transporter (TC 2.A.60) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:LYZ
gene id: 93934:LYZ
uniprot id: A0A8C2TXB7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyl hydrolase 22 family.
messages: Monomer.
messages: Secreted

93934:UBE3D
gene id: 93934:UBE3D
uniprot id: A0A8C2SVD8
names: Function
messages: E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and transfers it to substrates, generally promoting their degradation by the proteasome.

93934:CLK4
gene id: 93934:CLK4
uniprot id: A0A8C2SZ39
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:TRAF3
gene id: 93934:TRAF3
uniprot id: A0A8C2SR24
uniprot id: A0A8C2SR25
uniprot id: A0A8C2SSD4
uniprot id: A0A8C2Y5R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TNF receptor-associated factor family.
messages: Cytoplasm

93934:WEE2
gene id: 93934:WEE2
uniprot id: A0A8C2UEZ3
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily.
messages: Binds 2 magnesium ions per subunit.
messages: Nucleus

93934:ST8SIA3
gene id: 93934:ST8SIA3
uniprot id: A0A8C2SWT3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:ZIC4
gene id: 93934:ZIC4
uniprot id: A0A8C2TNC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

93934:TOMM5
gene id: 93934:TOMM5
uniprot id: A0A8C2T0S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

93934:TNC
gene id: 93934:TNC
uniprot id: A0A8C2U9F4
uniprot id: A0A8C2UB49
uniprot id: A0A8C2UCM0
uniprot id: A0A8C2UEE7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tenascin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:CNOT7
gene id: 93934:CNOT7
uniprot id: A0A8C2TE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

93934:HTR5A
gene id: 93934:HTR5A
uniprot id: A0A8C2SW21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:PLD1
gene id: 93934:PLD1
uniprot id: A0A8C2TVZ9
names: Similarity
messages: Belongs to the phospholipase D family.

93934:SNAP47
gene id: 93934:SNAP47
uniprot id: A0A8C2TGK0
uniprot id: A0A8C2TGW8
names: Similarity
messages: Belongs to the SVAP1 family.

93934:SLC7A14
gene id: 93934:SLC7A14
uniprot id: A0A8C2U4T5
names: Subcellular Location Annotation
messages: Membrane

93934:ATE1
gene id: 93934:ATE1
uniprot id: A0A8C2UCK6
names: Function
names: Similarity
messages: Belongs to the R-transferase family.
messages: Involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway.

93934:TAGLN3
gene id: 93934:TAGLN3
uniprot id: A0A8C2U590
names: Similarity
messages: Belongs to the calponin family.

93934:PTN
gene id: 93934:PTN
uniprot id: A0A8C2UAC8
names: Similarity
messages: Belongs to the pleiotrophin family.

93934:DMRT2
gene id: 93934:DMRT2
uniprot id: A0A8C2ST09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DMRT family.
messages: Nucleus

93934:TPPP
gene id: 93934:TPPP
uniprot id: A0A8C2U6W3
names: Similarity
messages: Belongs to the TPPP family.

93934:ADAMTS15
gene id: 93934:ADAMTS15
uniprot id: A0A8C2T6S6
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:SLC52A3
gene id: 93934:SLC52A3
uniprot id: A0A8C2Y7R1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the riboflavin transporter family.
messages: Cell membrane
messages: Membrane
messages: Plasma membrane transporter mediating the uptake by cells of the water soluble vitamin B2/riboflavin that plays a key role in biochemical oxidation-reduction reactions of the carbohydrate, lipid, and amino acid metabolism.

93934:CD180
gene id: 93934:CD180
uniprot id: A0A8C2TA32
names: Similarity
messages: Belongs to the Toll-like receptor family.

93934:CD40
gene id: 93934:CD40
uniprot id: A0A8C2T4H2
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:CDKN1A
gene id: 93934:CDKN1A
uniprot id: A0A8C2TAM2
names: Similarity
messages: Belongs to the CDI family.

93934:PANK4
gene id: 93934:PANK4
uniprot id: A0A8C2TB08
names: Similarity
names: Subunit
messages: Belongs to the type II pantothenate kinase family.
messages: Homodimer. Interacts with PKM.
messages: In the N-terminal section; belongs to the type II pantothenate kinase family.

93934:ACTL6A
gene id: 93934:ACTL6A
uniprot id: A0A8C2TR82
names: Similarity
messages: Belongs to the actin family.

93934:GAL3ST1
gene id: 93934:GAL3ST1
uniprot id: A0A8C2TSX7
uniprot id: A0A8C2TVA9
names: Similarity
messages: Belongs to the galactose-3-O-sulfotransferase family.

93934:GFOD1
gene id: 93934:GFOD1
uniprot id: A0A8C2U3S1
names: Similarity
messages: Belongs to the Gfo/Idh/MocA family.

93934:ZDHHC8
gene id: 93934:ZDHHC8
uniprot id: A0A8C2UAT9
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily.
messages: Golgi apparatus membrane
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

93934:ATP9B
gene id: 93934:ATP9B
uniprot id: A0A8C2U2S3
uniprot id: A0A8C2U5E2
uniprot id: A0A8C2U6P5
uniprot id: A0A8C2YFE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

93934:RPL3
gene id: 93934:RPL3
uniprot id: A0A8C2TR79
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

93934:FAM110D
gene id: 93934:FAM110D
uniprot id: A0A8C2TXR8
names: Similarity
messages: Belongs to the FAM110 family.

93934:ALDH1A1
gene id: 93934:ALDH1A1
uniprot id: A0A8C2T7J4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93934:ISM2
gene id: 93934:ISM2
uniprot id: A0A8C2U9I7
names: Similarity
messages: Belongs to the isthmin family.

93934:FAM110B
gene id: 93934:FAM110B
uniprot id: A0A8C2TGP3
names: Similarity
messages: Belongs to the FAM110 family.

93934:MAST4
gene id: 93934:MAST4
uniprot id: A0A8C2T8N6
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

93934:GLUL
gene id: 93934:GLUL
uniprot id: A0A8C2UKH3
names: Similarity
messages: Belongs to the glutamine synthetase family.

93934:MRPL10
gene id: 93934:MRPL10
uniprot id: A0A8C2U826
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

93934:ARHGEF28
gene id: 93934:ARHGEF28
uniprot id: A0A8C2SPJ0
uniprot id: A0A8C2SPK4
uniprot id: A0A8C2SR26
names: Subcellular Location Annotation
messages: Cytoplasm

93934:MRPL2
gene id: 93934:MRPL2
uniprot id: A0A8C2YDR9
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

93934:LOC107314079
gene id: 93934:LOC107314079
uniprot id: A0A8C2T8J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:BMP2
gene id: 93934:BMP2
uniprot id: A0A8C2SXW7
names: Similarity
messages: Belongs to the TGF-beta family.

93934:PANX3
gene id: 93934:PANX3
uniprot id: A0A8C2SZY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pannexin family.
messages: Cell membrane
messages: Membrane
messages: Structural component of the gap junctions and the hemichannels.
messages: gap junction

93934:LOC107321407
gene id: 93934:LOC107321407
uniprot id: A0A8C2TSF0
names: Similarity
messages: Belongs to the gonadal family.

93934:METAP2
gene id: 93934:METAP2
uniprot id: A0A8C2SYF7
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Binds EIF2S1 at low magnesium concentrations. Interacts strongly with the eIF-2 gamma-subunit EIF2S3.
messages: Contains approximately 12 O-linked N-acetylglucosamine (GlcNAc) residues. O-glycosylation is required for EIF2S1 binding.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm
messages: Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2/PKR and EIF2AK1/HCR. Plays a critical role in the regulation of protein synthesis.

93934:BARHL2
gene id: 93934:BARHL2
uniprot id: A0A8C2T983
names: Subcellular Location Annotation
messages: Nucleus

93934:ACADL
gene id: 93934:ACADL
uniprot id: A0A8C2TSU9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the acyl-CoA dehydrogenase family.
messages: Homotetramer.
messages: Mitochondrion matrix

93934:SOX10
gene id: 93934:SOX10
uniprot id: A0A8C2TNU6
names: Subcellular Location Annotation
messages: Nucleus

93934:FOXO6
gene id: 93934:FOXO6
uniprot id: A0A8C2TXX7
names: Subcellular Location Annotation
messages: Nucleus

93934:PIGH
gene id: 93934:PIGH
uniprot id: A0A8C2U186
names: Similarity
messages: Belongs to the PIGH family.

93934:NKAIN1
gene id: 93934:NKAIN1
uniprot id: A0A8C2TUX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NKAIN family.
messages: Cell membrane
messages: Membrane

93934:GABRA4
gene id: 93934:GABRA4
uniprot id: A0A8C2U4V6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ligand-gated ion channel (TC 1.A.9) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Synaptic cell membrane

93934:MAPK13
gene id: 93934:MAPK13
uniprot id: A0A8C2Y6F1
names: Similarity
names: Subunit
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Interacts with MAPK8IP2.

93934:PTGR2
gene id: 93934:PTGR2
uniprot id: A0A8C2TWC4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADP-dependent oxidoreductase L4BD family.
messages: Cytoplasm
messages: Monomer.

93934:STAMBPL1
gene id: 93934:STAMBPL1
uniprot id: A0A8C2U8G2
names: Similarity
messages: Belongs to the peptidase M67C family.

93934:CCDC85C
gene id: 93934:CCDC85C
uniprot id: A0A8C2SRW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC85 family.
messages: adherens junction

93934:RNPEPL1
gene id: 93934:RNPEPL1
uniprot id: A0A8C2TP91
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

93934:SNX5
gene id: 93934:SNX5
uniprot id: A0A8C2SUU0
names: Function
names: Similarity
messages: Belongs to the sorting nexin family.
messages: Involved in several stages of intracellular trafficking.

93934:BRIX1
gene id: 93934:BRIX1
uniprot id: A0A8C2Y804
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRX1 family.
messages: Required for biogenesis of the 60S ribosomal subunit.
messages: nucleolus

93934:PRPH2
gene id: 93934:PRPH2
uniprot id: A0A8C2TCU3
names: Similarity
messages: Belongs to the PRPH2/ROM1 family.

93934:NADK
gene id: 93934:NADK
uniprot id: A0A8C2TFQ7
names: Similarity
messages: Belongs to the NAD kinase family.

93934:MAP2
gene id: 93934:MAP2
uniprot id: A0A8C2TS56
names: Subcellular Location Annotation
messages: cytoskeleton

93934:LOC107321681
gene id: 93934:LOC107321681
uniprot id: A0A8C2TVY5
names: Similarity
messages: Belongs to the calycin superfamily. Lipocalin family.

93934:PLBD2
gene id: 93934:PLBD2
uniprot id: A0A8C2TYI4
names: Function
names: Similarity
messages: Belongs to the phospholipase B-like family.
messages: Putative phospholipase.

93934:CUL1
gene id: 93934:CUL1
uniprot id: A0A8C2T0F0
names: Similarity
messages: Belongs to the cullin family.

93934:DRAM1
gene id: 93934:DRAM1
uniprot id: A0A8C2UB22
names: Subcellular Location Annotation
messages: Membrane

93934:NOP58
gene id: 93934:NOP58
uniprot id: A0A8C2TUJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

93934:UBE2R2
gene id: 93934:UBE2R2
uniprot id: A0A8C2T3P0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:GPR89B
gene id: 93934:GPR89B
uniprot id: A0A8C2SVR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Golgi pH regulator (TC 1.A.38) family.
messages: Membrane

93934:ST3GAL6
gene id: 93934:ST3GAL6
uniprot id: A0A8C2U3V1
uniprot id: A0A8C2YF33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:LOC107318362
gene id: 93934:LOC107318362
uniprot id: A0A8C2TYW6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family.
messages: Secreted

93934:PUS7
gene id: 93934:PUS7
uniprot id: A0A8C2T3J9
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

93934:KATNA1
gene id: 93934:KATNA1
uniprot id: A0A8C2T3S7
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase activity is stimulated by microtubules, which promote homooligomerization. ATP-dependent microtubule severing is stimulated by interaction with KATNB1.
messages: Belongs to the AAA ATPase family. Katanin p60 subunit A1 subfamily.
messages: Can homooligomerize into hexameric rings, which may be promoted by interaction with microtubules. Interacts with KATNB1, which may serve as a targeting subunit.
messages: Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
messages: Cytoplasm
messages: centrosome
messages: spindle
messages: spindle pole

93934:RTCB
gene id: 93934:RTCB
uniprot id: A0A8C2U3S6
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RtcB family.
messages: Binds 2 manganese ions per subunit.
messages: Catalytic component of the tRNA-splicing ligase complex.
messages: Catalytic subunit of the tRNA-splicing ligase complex that acts by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester. May act as an RNA ligase with broad substrate specificity, and may function toward other RNAs.
messages: Cytoplasm
messages: Ligation probably proceeds through 3 nucleotidyl transfer steps, with 2',3'-cyclic phosphate termini being hydrolyzed to 3'-P termini in a step that precedes 3'-P activation with GMP. In the first nucleotidyl transfer step, RTCB reacts with GTP to form a covalent RTCB-histidine-GMP intermediate with release of PPi; in the second step, the GMP moiety is transferred to the RNA 3'-P; in the third step, the 5'-OH from the opposite RNA strand attacks the activated 3'-P to form a 3',5'-phosphodiester bond and release GMP.

93934:TINAG
gene id: 93934:TINAG
uniprot id: A0A8C2T5F9
uniprot id: A0A8C2T7X3
names: Similarity
messages: Belongs to the peptidase C1 family.

93934:SMARCA2
gene id: 93934:SMARCA2
uniprot id: A0A8C2SR46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

93934:HADHA
gene id: 93934:HADHA
uniprot id: A0A8C2TM45
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.
messages: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family.

93934:EXOSC3
gene id: 93934:EXOSC3
uniprot id: A0A8C2TNZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP40 family.
messages: Cytoplasm

93934:SLC45A4
gene id: 93934:SLC45A4
uniprot id: A0A8C2TIU0
names: Subcellular Location Annotation
messages: Membrane

93934:TARS1
gene id: 93934:TARS1
uniprot id: A0A8C2T1Q9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

93934:HMX3
gene id: 93934:HMX3
uniprot id: A0A8C2UAB9
names: Subcellular Location Annotation
messages: Nucleus

93934:STEAP3
gene id: 93934:STEAP3
uniprot id: A0A8C2UIY9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STEAP family.
messages: Endosome membrane
messages: Membrane

93934:SHCBP1
gene id: 93934:SHCBP1
uniprot id: A0A8C2TTP7
names: Subcellular Location Annotation
messages: spindle

93934:GLI2
gene id: 93934:GLI2
uniprot id: A0A8C2TQ41
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLI C2H2-type zinc-finger protein family.
messages: Nucleus

93934:ME3
gene id: 93934:ME3
uniprot id: A0A8C2SWL9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

93934:XKR6
gene id: 93934:XKR6
uniprot id: A0A8C2TQS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:EIF2D
gene id: 93934:EIF2D
uniprot id: A0A8C2TWH9
names: Similarity
messages: Belongs to the eIF2D family.

93934:NDOR1
gene id: 93934:NDOR1
uniprot id: A0A8C2U103
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with CIAPIN1; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of CIAPIN1, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. It can also reduce the [2Fe-2S] cluster of CISD1 and activate this protein implicated in Fe/S cluster repair.
messages: perinuclear region

93934:MRPS30
gene id: 93934:MRPS30
uniprot id: A0A8C2THK6
names: Subcellular Location Annotation
messages: Mitochondrion

93934:TBC1D24
gene id: 93934:TBC1D24
uniprot id: A0A8C2U4J9
names: Subcellular Location Annotation
names: Subunit
messages: Cell membrane
messages: Cytoplasmic vesicle membrane
messages: Interacts with ARF6.
messages: Membrane
messages: Presynapse
messages: Synapse

93934:HPSE2
gene id: 93934:HPSE2
uniprot id: A0A8C2UDD0
names: Similarity
messages: Belongs to the glycosyl hydrolase 79 family.

93934:TBPL2
gene id: 93934:TBPL2
uniprot id: A0A8C2Y7Z4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

93934:RAB3IL1
gene id: 93934:RAB3IL1
uniprot id: A0A8C2U3W2
names: Similarity
messages: Belongs to the SEC2 family.

93934:NOP14
gene id: 93934:NOP14
uniprot id: A0A8C2UAE3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

93934:SEMA3G
gene id: 93934:SEMA3G
uniprot id: A0A8C2TLP1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:SIRT4
gene id: 93934:SIRT4
uniprot id: A0A8C2TQX1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sirtuin family. Class II subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Mitochondrion matrix
messages: NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues.

93934:RAB39B
gene id: 93934:RAB39B
uniprot id: A0A8C2YEX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rab family.
messages: Cell membrane
messages: Membrane

93934:SPATS2
gene id: 93934:SPATS2
uniprot id: A0A8C2SV44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPATS2 family.
messages: Cytoplasm

93934:LMX1B
gene id: 93934:LMX1B
uniprot id: A0A8C2TJ67
names: Subcellular Location Annotation
messages: Nucleus

93934:HHATL
gene id: 93934:HHATL
uniprot id: A0A8C2THS3
names: Subcellular Location Annotation
messages: Membrane

93934:FURIN
gene id: 93934:FURIN
uniprot id: A0A8C2SMY3
names: Similarity
messages: Belongs to the peptidase S8 family.

93934:CCT7
gene id: 93934:CCT7
uniprot id: A0A8C2T7M0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

93934:MCTP2
gene id: 93934:MCTP2
uniprot id: A0A8C2UCJ9
names: Subcellular Location Annotation
messages: Membrane

93934:GGNBP2
gene id: 93934:GGNBP2
uniprot id: A0A8C2U2C9
names: Function
messages: May be involved in spermatogenesis.

93934:KCND3
gene id: 93934:KCND3
uniprot id: A0A8C2TYT2
uniprot id: A0A8C2TYW2
names: Subcellular Location Annotation
messages: Membrane
messages: dendrite

93934:KREMEN1
gene id: 93934:KREMEN1
uniprot id: A0A8C2Y9E5
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6.

93934:LOC107322047
gene id: 93934:LOC107322047
uniprot id: A0A8C2UA49
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

93934:PERP
gene id: 93934:PERP
uniprot id: A0A8C2TB70
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM47 family.
messages: Membrane

93934:BCL2A1
gene id: 93934:BCL2A1
uniprot id: A0A8C2UCW6
names: Similarity
messages: Belongs to the Bcl-2 family.

93934:FAM83B
gene id: 93934:FAM83B
uniprot id: A0A8C2TAU0
names: Similarity
messages: Belongs to the FAM83 family.

93934:TMEM9
gene id: 93934:TMEM9
uniprot id: A0A8C2TBD2
names: Similarity
messages: Belongs to the TMEM9 family.

93934:AMER3
gene id: 93934:AMER3
uniprot id: A0A8C2TUP3
names: Similarity
messages: Belongs to the Amer family.

93934:FGF9
gene id: 93934:FGF9
uniprot id: A0A8C2SPF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

93934:ACBD5
gene id: 93934:ACBD5
uniprot id: A0A8C2SWY6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters.
messages: Belongs to the ATG37 family.
messages: Membrane

93934:FHL5
gene id: 93934:FHL5
uniprot id: A0A8C2SKP9
uniprot id: A0A8C2SLZ2
names: Function
names: Subcellular Location Annotation
messages: May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
messages: Nucleus

93934:HLCS
gene id: 93934:HLCS
uniprot id: A0A8C2Y8T7
names: Similarity
messages: Belongs to the biotin--protein ligase family.

93934:HHIP
gene id: 93934:HHIP
uniprot id: A0A8C2SQE6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ROS1
gene id: 93934:ROS1
uniprot id: A0A8C2TBJ1
uniprot id: A0A8C2Y9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

93934:MCOLN3
gene id: 93934:MCOLN3
uniprot id: A0A8C2TAX5
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

93934:PTPN14
gene id: 93934:PTPN14
uniprot id: A0A8C2T4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.
messages: cytoskeleton

93934:LOC107325038
gene id: 93934:LOC107325038
uniprot id: A0A8C2U956
names: Domain
names: Function
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

93934:AK3
gene id: 93934:AK3
uniprot id: A0A8C2Y680
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

93934:BEST4
gene id: 93934:BEST4
uniprot id: A0A8C2TBU4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bestrophin family.
messages: Cell membrane
messages: Forms chloride channels.
messages: Membrane

93934:MCTS1
gene id: 93934:MCTS1
uniprot id: A0A8C2U7R7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MCTS1 family.
messages: Cytoplasm

93934:LOC107308586
gene id: 93934:LOC107308586
uniprot id: A0A8C2SZ60
names: Similarity
messages: Belongs to the globin family.

93934:FKBP5
gene id: 93934:FKBP5
uniprot id: A0A8C2Y5U3
names: Subcellular Location Annotation
messages: Nucleus

93934:INIP
gene id: 93934:INIP
uniprot id: A0A8C2SQW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SOSS-C family.
messages: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs).
messages: Component of the SOSS complex.
messages: Nucleus

93934:DLL1
gene id: 93934:DLL1
uniprot id: A0A8C2SVB7
names: Caution
names: Function
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Putative Notch ligand involved in the mediation of Notch signaling.

93934:WNT5A
gene id: 93934:WNT5A
uniprot id: A0A8C2TRN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Wnt family.
messages: Ligand for members of the frizzled family of seven transmembrane receptors.
messages: extracellular matrix

93934:LOC107323822
gene id: 93934:LOC107323822
uniprot id: A0A8C2U4P1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

93934:LOC107325926
gene id: 93934:LOC107325926
uniprot id: A0A8C2SXI0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

93934:ASIC2
gene id: 93934:ASIC2
uniprot id: A0A8C2U8T4
names: Subcellular Location Annotation
messages: Membrane

93934:ETV6
gene id: 93934:ETV6
uniprot id: A0A8C2U0A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:CACNG2
gene id: 93934:CACNG2
uniprot id: A0A8C2TSC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
messages: Membrane
messages: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

93934:HOOK1
gene id: 93934:HOOK1
uniprot id: A0A8C2TPY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the hook family.
messages: cytoskeleton

93934:RPL32
gene id: 93934:RPL32
uniprot id: A0A8C2UEU2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

93934:SEMA4D
gene id: 93934:SEMA4D
uniprot id: A0A8C2TCV7
uniprot id: A0A8C2TDE8
uniprot id: A0A8C2TGE5
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:MAP2K4
gene id: 93934:MAP2K4
uniprot id: A0A8C2UB34
uniprot id: A0A8C2UDF7
uniprot id: A0A8C2UFA9
uniprot id: A0A8C2UGD6
names: Similarity
messages: Belongs to the protein kinase superfamily.

93934:HPCAL4
gene id: 93934:HPCAL4
uniprot id: A0A8C2T0G2
names: Function
messages: May be involved in the calcium-dependent regulation of rhodopsin phosphorylation.

93934:LOC107318160
gene id: 93934:LOC107318160
uniprot id: A0A8C2YBW4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RRM NCBP2 family.
messages: Component of the cap-binding complex (CBC), which binds co-transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U snRNA and intronless mRNAs export from the nucleus. The CBC complex is essential for a pioneer round of mRNA translation, before steady state translation when the CBC complex is replaced by cytoplasmic cap-binding protein eIF4E. The pioneer round of mRNA translation mediated by the CBC complex plays a central role in nonsense-mediated mRNA decay (NMD), NMD only taking place in mRNAs bound to the CBC complex, but not on eIF4E-bound mRNAs. The CBC complex enhances NMD in mRNAs containing at least one exon-junction complex (EJC), promoting the interaction between upf1 and upf2. The CBC complex is also involved in 'failsafe' NMD, which is independent of the EJC complex, while it does not participate in Staufen-mediated mRNA decay (SMD). During cell proliferation, the CBC complex is also involved in microRNAs (miRNAs) biogenesis via its interaction with srrt/ars2, thereby being required for miRNA-mediated RNA interference. The CBC complex also acts as a negative regulator of parn, thereby acting as an inhibitor of mRNA deadenylation. In the CBC complex, ncbp2/cbp20 recognizes and binds capped RNAs (m7GpppG-capped RNA) but requires ncbp1/cbp80 to stabilize the movement of its N-terminal loop and lock the CBC into a high affinity cap-binding state with the cap structure. The conventional cap-binding complex with NCBP2 binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus.
messages: Component of the nuclear cap-binding complex (CBC), a heterodimer composed of ncbp1/cbp80 and ncbp2/cbp20 that interacts with m7GpppG-capped RNA.
messages: Nucleus

93934:THG1L
gene id: 93934:THG1L
uniprot id: A0A8C2TGI4
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

93934:SDC3
gene id: 93934:SDC3
uniprot id: A0A8C2TXC0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syndecan proteoglycan family.
messages: Cell surface proteoglycan.
messages: Membrane

93934:BIRC2
gene id: 93934:BIRC2
uniprot id: A0A8C2SVC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IAP family.
messages: Cytoplasm
messages: Nucleus

93934:ATP23
gene id: 93934:ATP23
uniprot id: A0A8C2TRK2
names: Similarity
messages: Belongs to the peptidase M76 family.

93934:TMPO
gene id: 93934:TMPO
uniprot id: A0A8C2SXG5
uniprot id: A0A8C2Y7B0
names: Similarity
messages: Belongs to the LEM family.

93934:HOXD12
gene id: 93934:HOXD12
uniprot id: A0A8C2YF82
names: Subcellular Location Annotation
messages: Nucleus

93934:MLH3
gene id: 93934:MLH3
uniprot id: A0A8C2U6X8
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

93934:DNM1L
gene id: 93934:DNM1L
uniprot id: A0A8C2YH07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
messages: Endomembrane system
messages: Golgi apparatus
messages: Membrane
messages: Mitochondrion outer membrane
messages: Peroxisome
messages: clathrin-coated pit
messages: cytosol
messages: synaptic vesicle membrane

93934:RPAIN
gene id: 93934:RPAIN
uniprot id: A0A8C2TAI5
names: Subcellular Location Annotation
messages: Nucleus

93934:GALNT1
gene id: 93934:GALNT1
uniprot id: A0A8C2YDE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:RNASEH1
gene id: 93934:RNASEH1
uniprot id: A0A8C2TAE9
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

93934:SNTB1
gene id: 93934:SNTB1
uniprot id: A0A8C2SZ05
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the syntrophin family.
messages: Cell junction
messages: cytoskeleton

93934:XKR9
gene id: 93934:XKR9
uniprot id: A0A8C2THZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XK family.
messages: Membrane

93934:SPR
gene id: 93934:SPR
uniprot id: A0A8C2T865
names: Similarity
messages: Belongs to the sepiapterin reductase family.

93934:CALB1
gene id: 93934:CALB1
uniprot id: A0A8C2SPX4
names: Function
names: Similarity
messages: Belongs to the calbindin family.
messages: Buffers cytosolic calcium. May stimulate a membrane Ca(2+)-ATPase and a 3',5'-cyclic nucleotide phosphodiesterase.

93934:LOC107309619
gene id: 93934:LOC107309619
uniprot id: A0A8C2TZ83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.
messages: cytoskeleton

93934:LOC107306162
gene id: 93934:LOC107306162
uniprot id: A0A8C2T8T7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alpha/beta interferon family.
messages: Has antiviral activities.
messages: Secreted

93934:CRYAA
gene id: 93934:CRYAA
uniprot id: A0A8C2T8W3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small heat shock protein (HSP20) family.
messages: Contributes to the transparency and refractive index of the lens. May act as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions.
messages: Cytoplasm

93934:STARD3
gene id: 93934:STARD3
uniprot id: A0A8C2SQD9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STARD3 family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Membrane

93934:LOC107317596
gene id: 93934:LOC107317596
uniprot id: A0A8C2TCU6
names: Similarity
messages: Belongs to the amidase family.

93934:KCNJ8
gene id: 93934:KCNJ8
uniprot id: A0A8C2SVC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family.
messages: Membrane

93934:RPS15
gene id: 93934:RPS15
uniprot id: A0A8C2YAR5
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

93934:SCNN1G
gene id: 93934:SCNN1G
uniprot id: A0A8C2TFK6
names: Subcellular Location Annotation
messages: Membrane

93934:MRPS21
gene id: 93934:MRPS21
uniprot id: A0A8C2TTY1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

93934:BTG2
gene id: 93934:BTG2
uniprot id: A0A8C2U6H7
names: Similarity
messages: Belongs to the BTG family.

93934:IQCD
gene id: 93934:IQCD
uniprot id: A0A8C2TXR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DRC10 family.
messages: Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.
messages: flagellum axoneme

93934:LOC107309552
gene id: 93934:LOC107309552
uniprot id: A0A8C2YDU0
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:EBF1
gene id: 93934:EBF1
uniprot id: A0A8C2TJ25
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COE family.
messages: Nucleus

93934:CDKN1B
gene id: 93934:CDKN1B
uniprot id: A0A8C2YE75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDI family.
messages: Cytoplasm
messages: Endosome
messages: Nucleus

93934:PRPF3
gene id: 93934:PRPF3
uniprot id: A0A8C2TW69
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).

93934:ERGIC1
gene id: 93934:ERGIC1
uniprot id: A0A8C2T955
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

93934:TMEM200A
gene id: 93934:TMEM200A
uniprot id: A0A8C2TAN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM200 family.
messages: Membrane

93934:RAD17
gene id: 93934:RAD17
uniprot id: A0A8C2SQE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

93934:C2H7orf25
gene id: 93934:C2H7orf25
uniprot id: A0A8C2SLY2
names: Similarity
messages: Belongs to the UPF0415 family.

93934:EIPR1
gene id: 93934:EIPR1
uniprot id: A0A8C2T884
uniprot id: A0A8C2Y993
names: Similarity
messages: Belongs to the WD repeat EIPR1 family.

93934:ANXA6
gene id: 93934:ANXA6
uniprot id: A0A8C2T3L2
uniprot id: A0A8C2T691
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A pair of annexin repeats may form one binding site for calcium and phospholipid.
messages: Belongs to the annexin family.
messages: May associate with CD21. May regulate the release of Ca(2+) from intracellular stores.
messages: Melanosome

93934:GUF1
gene id: 93934:GUF1
uniprot id: A0A8C2TZJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

93934:LOC107324399
gene id: 93934:LOC107324399
uniprot id: A0A8C2TVD8
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:LOC107317986
gene id: 93934:LOC107317986
uniprot id: A0A8C2SYN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin family. SUMO subfamily.
messages: Nucleus

93934:CLIC4
gene id: 93934:CLIC4
uniprot id: A0A8C2U2K9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel CLIC family.
messages: Membrane

93934:PIGO
gene id: 93934:PIGO
uniprot id: A0A8C2T0Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

93934:LOC107317428
gene id: 93934:LOC107317428
uniprot id: A0A8C2SMU9
uniprot id: A0A8C2SN66
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FRRS1 family.
messages: Membrane

93934:PUS7L
gene id: 93934:PUS7L
uniprot id: A0A8C2TQH7
uniprot id: A0A8C2TQS7
uniprot id: A0A8C2YCH8
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

93934:TNIP2
gene id: 93934:TNIP2
uniprot id: A0A8C2SP94
names: Subcellular Location Annotation
messages: Cytoplasm

93934:ARL5A
gene id: 93934:ARL5A
uniprot id: A0A8C2UG21
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

93934:MAN2B2
gene id: 93934:MAN2B2
uniprot id: A0A8C2UA43
names: Cofactor
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.
messages: Binds 1 zinc ion per subunit.

93934:LOC107324464
gene id: 93934:LOC107324464
uniprot id: A0A8C2TR65
names: Similarity
names: Subunit
messages: Belongs to the avian keratin family.
messages: The avian keratins (F-ker, S-ker, C-ker and B-ker) are a complex mixture of very similar polypeptides.

93934:ZADH2
gene id: 93934:ZADH2
uniprot id: A0A8C2T6L8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

93934:GALNT2
gene id: 93934:GALNT2
uniprot id: A0A8C2SVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:LOC107311272
gene id: 93934:LOC107311272
uniprot id: A0A8C2TJZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Microsome membrane

93934:HTATSF1
gene id: 93934:HTATSF1
uniprot id: A0A8C2YEB6
names: Similarity
messages: Belongs to the HTATSF1 family.

93934:VIP
gene id: 93934:VIP
uniprot id: A0A8C2T551
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted
messages: VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder.

93934:DHX58
gene id: 93934:DHX58
uniprot id: A0A8C2SWU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RLR subfamily.
messages: Cytoplasm

93934:SLC16A9
gene id: 93934:SLC16A9
uniprot id: A0A8C2TSE4
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107312297
gene id: 93934:LOC107312297
uniprot id: A0A8C2TGC2
names: Subcellular Location Annotation
messages: Membrane

93934:PDE8B
gene id: 93934:PDE8B
uniprot id: A0A8C2Y8V6
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE8 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:POLR2L
gene id: 93934:POLR2L
uniprot id: A0A8C2U4B8
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

93934:ADGB
gene id: 93934:ADGB
uniprot id: A0A8C2T0B0
names: Caution
names: Similarity
messages: Belongs to the peptidase C2 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ENDOU
gene id: 93934:ENDOU
uniprot id: A0A8C2UE66
names: Similarity
names: Subunit
messages: Belongs to the ENDOU family.
messages: Monomer.

93934:LOC107314207
gene id: 93934:LOC107314207
uniprot id: A0A8C2TPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:TMEM70
gene id: 93934:TMEM70
uniprot id: A0A8C2TI09
names: Similarity
messages: Belongs to the TMEM70 family.

93934:PTPN11
gene id: 93934:PTPN11
uniprot id: A0A8C2T962
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
messages: Cytoplasm

93934:PLPPR4
gene id: 93934:PLPPR4
uniprot id: A0A8C2SLV3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

93934:TXNDC5
gene id: 93934:TXNDC5
uniprot id: A0A8C2TZP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

93934:MCM5
gene id: 93934:MCM5
uniprot id: A0A8C2U3Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

93934:SSTR5
gene id: 93934:SSTR5
uniprot id: A0A8C2T0L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:ITPRIPL2
gene id: 93934:ITPRIPL2
uniprot id: A0A8C2TUQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ITPRIP family.
messages: Belongs to the mab-21 family.
messages: Membrane

93934:CRMP1
gene id: 93934:CRMP1
uniprot id: A0A8C2U6T0
uniprot id: A0A8C2YFT6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.

93934:MED1
gene id: 93934:MED1
uniprot id: A0A8C2SUC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

93934:RASGRP1
gene id: 93934:RASGRP1
uniprot id: A0A8C2TY81
uniprot id: A0A8C2U1S2
uniprot id: A0A8C2U324
names: Similarity
messages: Belongs to the RASGRP family.

93934:SRF
gene id: 93934:SRF
uniprot id: A0A8C2TZ55
names: Subcellular Location Annotation
messages: Nucleus

93934:NDUFB3
gene id: 93934:NDUFB3
uniprot id: A0A8C2TWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
messages: Belongs to the complex I NDUFB3 subunit family.
messages: Mitochondrion inner membrane

93934:B4GALNT4
gene id: 93934:B4GALNT4
uniprot id: A0A8C2TSE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chondroitin N-acetylgalactosaminyltransferase family.
messages: Golgi stack membrane
messages: Membrane
messages: Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'-diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans.

93934:CCDC172
gene id: 93934:CCDC172
uniprot id: A0A8C2UDN2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCDC172 family.
messages: Cytoplasm

93934:XPO6
gene id: 93934:XPO6
uniprot id: A0A8C2YEQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus

93934:FAM53B
gene id: 93934:FAM53B
uniprot id: A0A8C2Y509
names: Similarity
messages: Belongs to the FAM53 family.

93934:LOC107325879
gene id: 93934:LOC107325879
uniprot id: A0A8C2SYE5
names: Similarity
messages: Belongs to the sulfotransferase 1 family.

93934:CTPS1
gene id: 93934:CTPS1
uniprot id: A0A8C2YDQ9
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

93934:MOCOS
gene id: 93934:MOCOS
uniprot id: A0A8C2YDE1
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. MOCOS subfamily.
messages: Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.

93934:EDA2R
gene id: 93934:EDA2R
uniprot id: A0A8C2SVJ3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:HMGCS1
gene id: 93934:HMGCS1
uniprot id: A0A8C2TFH6
uniprot id: A0A8C2TI82
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

93934:ABCG1
gene id: 93934:ABCG1
uniprot id: A0A8C2TAP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
messages: Membrane

93934:RBP7
gene id: 93934:RBP7
uniprot id: A0A0E3UQT3
names: Similarity
messages: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.

93934:AGO3
gene id: 93934:AGO3
uniprot id: A0A8C2U3A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the argonaute family. Ago subfamily.
messages: P-body
messages: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.

93934:MEOX1
gene id: 93934:MEOX1
uniprot id: A0A8C2U7Y2
names: Subcellular Location Annotation
messages: Nucleus

93934:CD36
gene id: 93934:CD36
uniprot id: A0A8C2T1U5
names: Similarity
names: Subcellular Location Annotation
messages: Apical cell membrane
messages: Belongs to the CD36 family.
messages: Cell membrane
messages: Golgi apparatus
messages: Membrane
messages: Membrane raft

93934:THSD1
gene id: 93934:THSD1
uniprot id: A0A8C2U8W5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the plasmodium circumsporozoite protein family.
messages: Cell membrane
messages: Cytoplasm
messages: In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.
messages: Membrane

93934:FGF2
gene id: 93934:FGF2
uniprot id: A0A8C2STW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Nucleus
messages: Secreted

93934:DNAJA4
gene id: 93934:DNAJA4
uniprot id: A0A8C2TBJ9
names: Subcellular Location Annotation
messages: Membrane

93934:LOC107310307
gene id: 93934:LOC107310307
uniprot id: A0A8C2SLM6
names: Function
names: Similarity
messages: Belongs to the alpha-carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93934:MBD4
gene id: 93934:MBD4
uniprot id: A0A8C2YHE5
names: Subcellular Location Annotation
messages: Nucleus

93934:STRN
gene id: 93934:STRN
uniprot id: A0A8C2TNA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat striatin family.
messages: Membrane

93934:INSRR
gene id: 93934:INSRR
uniprot id: A0A8C2TQX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily.
messages: Membrane

93934:KIF16B
gene id: 93934:KIF16B
uniprot id: A0A8C2TIM4
uniprot id: A0A8C2TKG4
uniprot id: A0A8C2YBG8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

93934:P2RY2
gene id: 93934:P2RY2
uniprot id: A0A8C2T2T6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Membrane

93934:RIN3
gene id: 93934:RIN3
uniprot id: A0A8C2SR78
names: Similarity
messages: Belongs to the RIN (Ras interaction/interference) family.

93934:DDX18
gene id: 93934:DDX18
uniprot id: A0A8C2UIW7
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.

93934:CAV2
gene id: 93934:CAV2
uniprot id: A0A8C2TP39
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the caveolin family.
messages: Cell membrane
messages: Golgi apparatus membrane
messages: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.
messages: Membrane
messages: caveola

93934:C1H12orf57
gene id: 93934:C1H12orf57
uniprot id: A0A8C2U3P9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0456 family.
messages: Cytoplasm

93934:AVPR1A
gene id: 93934:AVPR1A
uniprot id: A0A8C2TU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.
messages: Cell membrane
messages: Membrane

93934:BCL2L10
gene id: 93934:BCL2L10
uniprot id: A0A8C2U8D6
names: Similarity
messages: Belongs to the Bcl-2 family.

93934:LOC107312412
gene id: 93934:LOC107312412
uniprot id: A0A8C2T7P9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

93934:PIGC
gene id: 93934:PIGC
uniprot id: A0A8C2UGU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

93934:COQ10B
gene id: 93934:COQ10B
uniprot id: A0A8C2Y6U6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

93934:EZH2
gene id: 93934:EZH2
uniprot id: A0A8C2T1N5
names: Subcellular Location Annotation
messages: Nucleus

93934:NSDHL
gene id: 93934:NSDHL
uniprot id: A0A8C2TZL1
names: Similarity
messages: Belongs to the 3-beta-HSD family.

93934:LOC107321560
gene id: 93934:LOC107321560
uniprot id: A0A8C2YDV4
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:SPTBN1
gene id: 93934:SPTBN1
uniprot id: A0A8C2U0R6
names: Similarity
messages: Belongs to the spectrin family.

93934:VAMP7
gene id: 93934:VAMP7
uniprot id: A0A8C2TZA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Membrane

93934:LTN1
gene id: 93934:LTN1
uniprot id: A0A8C2SZM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

93934:ISYNA1
gene id: 93934:ISYNA1
uniprot id: A0A8C2TKR6
names: Similarity
messages: Belongs to the myo-inositol 1-phosphate synthase family.

93934:GPR135
gene id: 93934:GPR135
uniprot id: A0A8C2Y7F4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:SLC35B3
gene id: 93934:SLC35B3
uniprot id: A0A8C2TZY6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleotide-sugar transporter family. SLC35B subfamily.
messages: Membrane

93934:HNF4G
gene id: 93934:HNF4G
uniprot id: A0A8C2TI30
uniprot id: A0A8C2TKF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family.
messages: Nucleus

93934:LOC107317030
gene id: 93934:LOC107317030
uniprot id: A0A8C2YCA9
names: Subcellular Location Annotation
messages: Nucleus

93934:IDI1
gene id: 93934:IDI1
uniprot id: A0A8C2SSA9
names: Function
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.
messages: Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).

93934:KLHL36
gene id: 93934:KLHL36
uniprot id: A0A8C2TVP9
names: Function
messages: Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

93934:GDF10
gene id: 93934:GDF10
uniprot id: A0A8C2U7U4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TGF-beta family.
messages: Homodimer.
messages: Secreted

93934:FAM135A
gene id: 93934:FAM135A
uniprot id: A0A8C2T5L6
uniprot id: A0A8C2T6S3
names: Similarity
messages: Belongs to the FAM135 family.

93934:RGMA
gene id: 93934:RGMA
uniprot id: A0A8C2UHH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the repulsive guidance molecule (RGM) family.
messages: Cell membrane
messages: Membrane

93934:SLC25A14
gene id: 93934:SLC25A14
uniprot id: A0A8C2STS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:ST7L
gene id: 93934:ST7L
uniprot id: A0A8C2YEK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ST7 family.
messages: Membrane

93934:REV3L
gene id: 93934:REV3L
uniprot id: A0A8C2TCY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

93934:SEC24C
gene id: 93934:SEC24C
uniprot id: A0A8C2TXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: cytosol

93934:B4GALT2
gene id: 93934:B4GALT2
uniprot id: A0A8C2TBP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 7 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

93934:UBE2G2
gene id: 93934:UBE2G2
uniprot id: A0A8C2T1S0
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

93934:GCM1
gene id: 93934:GCM1
uniprot id: A0A8C2Y902
names: Subcellular Location Annotation
messages: Nucleus

93934:ARG2
gene id: 93934:ARG2
uniprot id: A0A8C2U2I1
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

93934:DTX3L
gene id: 93934:DTX3L
uniprot id: A0A8C2UIZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Deltex family.
messages: Cytoplasm

93934:TXLNB
gene id: 93934:TXLNB
uniprot id: A0A8C2Y9E1
names: Similarity
messages: Belongs to the taxilin family.

93934:PLIN1
gene id: 93934:PLIN1
uniprot id: A0A8C2UF81
names: Similarity
messages: Belongs to the perilipin family.

93934:PRRX1
gene id: 93934:PRRX1
uniprot id: A0A8C2UKI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the paired homeobox family.
messages: Nucleus

93934:B3GLCT
gene id: 93934:B3GLCT
uniprot id: A0A8C2YH53
names: Subcellular Location Annotation
messages: Membrane

93934:DYNC2LI1
gene id: 93934:DYNC2LI1
uniprot id: A0A8C2TG61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dynein light intermediate chain family.
messages: centrosome
messages: cilium
messages: cilium axoneme
messages: cilium basal body

93934:PSMA7
gene id: 93934:PSMA7
uniprot id: A0A8C2SRI7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.

93934:NXPH3
gene id: 93934:NXPH3
uniprot id: A0A8C2U9K1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the neurexophilin family.
messages: May be signaling molecules that resemble neuropeptides.
messages: Secreted

93934:FTH1
gene id: 93934:FTH1
uniprot id: Q6PRV1
names: Function
names: Similarity
messages: Belongs to the ferritin family.
messages: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation.

93934:CACNA2D2
gene id: 93934:CACNA2D2
uniprot id: A0A8C2T045
names: Similarity
messages: Belongs to the calcium channel subunit alpha-2/delta family.

93934:RRAGC
gene id: 93934:RRAGC
uniprot id: A0A8C2U0W6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Cytoplasm
messages: Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade.
messages: Lysosome

93934:EDN1
gene id: 93934:EDN1
uniprot id: A0A8C2U4V1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endothelin/sarafotoxin family.
messages: Secreted

93934:ELL
gene id: 93934:ELL
uniprot id: A0A8C2TMH1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELL/occludin family.
messages: Nucleus

93934:FUT8
gene id: 93934:FUT8
uniprot id: A0A8C2THU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 23 family.
messages: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.
messages: Golgi stack membrane
messages: Membrane

93934:ST8SIA4
gene id: 93934:ST8SIA4
uniprot id: A0A8C2TF63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 29 family.
messages: Membrane

93934:UTRN
gene id: 93934:UTRN
uniprot id: A0A8C2SYW9
uniprot id: A0A8C2T0P5
uniprot id: A0A8C2T1V6
names: Function
names: Subcellular Location Annotation
messages: May play a role in anchoring the cytoskeleton to the plasma membrane.
messages: cytoskeleton

93934:LOC107313393
gene id: 93934:LOC107313393
uniprot id: A0A8C2TG95
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93934:ADCYAP1
gene id: 93934:ADCYAP1
uniprot id: A0A8C2TD01
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glucagon family.
messages: Secreted

93934:HAPLN3
gene id: 93934:HAPLN3
uniprot id: A0A8C2UBL1
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107314866
gene id: 93934:LOC107314866
uniprot id: A0A8C2TTC1
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

93934:NOX1
gene id: 93934:NOX1
uniprot id: A0A8C2YEC0
names: Subcellular Location Annotation
messages: Membrane

93934:SLC22A3
gene id: 93934:SLC22A3
uniprot id: A0A8C2SW89
names: Similarity
messages: Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

93934:LOC107308806
gene id: 93934:LOC107308806
uniprot id: A0A1Q2TSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cathelicidin family.
messages: Secreted

93934:DCK
gene id: 93934:DCK
uniprot id: A0A8C2SNT2
names: Similarity
messages: Belongs to the DCK/DGK family.

93934:KCNE2
gene id: 93934:KCNE2
uniprot id: A0A8C2T4S3
names: Similarity
messages: Belongs to the potassium channel KCNE family.

93934:ADAMTS7
gene id: 93934:ADAMTS7
uniprot id: A0A8C2UD50
uniprot id: A0A8C2UHX3
names: Caution
names: Cofactor
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: extracellular matrix

93934:LOC107312449
gene id: 93934:LOC107312449
uniprot id: A0A8C2SQJ3
names: Similarity
messages: Belongs to the cytochrome P450 family.

93934:SLC25A20
gene id: 93934:SLC25A20
uniprot id: A0A8C2U4C9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

93934:LHX5
gene id: 93934:LHX5
uniprot id: A0A8C2YDX0
names: Subcellular Location Annotation
messages: Nucleus

93934:SERINC4
gene id: 93934:SERINC4
uniprot id: A0A8C2Y4T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

93934:POLR2E
gene id: 93934:POLR2E
uniprot id: A0A8C2TED7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the lower jaw surrounding the central large cleft and thought to grab the incoming DNA template. Seems to be the major component in this process.
messages: Nucleus

93934:LOC107321581
gene id: 93934:LOC107321581
uniprot id: A0A8C2TYC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POU transcription factor family.
messages: Nucleus

93934:KCTD10
gene id: 93934:KCTD10
uniprot id: A0A8C2Y8R4
names: Similarity
messages: Belongs to the BACURD family.

93934:GNB3
gene id: 93934:GNB3
uniprot id: A0A8C2U3P0
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

93934:ATP2A2
gene id: 93934:ATP2A2
uniprot id: A0A8C2UB96
uniprot id: A0A8C2UGY4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Sarcoplasmic reticulum membrane

93934:CLDN10
gene id: 93934:CLDN10
uniprot id: A0A8C2U9U3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the claudin family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
messages: tight junction

93934:HTR2C
gene id: 93934:HTR2C
uniprot id: A0A8C2TRW0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with MPDZ. Interacts with ARRB2.
messages: Membrane

93934:CLSTN1
gene id: 93934:CLSTN1
uniprot id: A0A8C2TGU9
uniprot id: A0A8C2TGW2
uniprot id: A0A8C2YB24
names: Subcellular Location Annotation
messages: Cell membrane
messages: Golgi apparatus membrane
messages: Membrane

93934:BARX2
gene id: 93934:BARX2
uniprot id: A0A8C2T1L8
names: Subcellular Location Annotation
messages: Nucleus

93934:A4GNT
gene id: 93934:A4GNT
uniprot id: A0A8C2UC63
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 32 family.
messages: Golgi apparatus membrane

93934:CPLX4
gene id: 93934:CPLX4
uniprot id: A0A8C2T1B3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complexin/synaphin family.
messages: Synapse

93934:ADAM12
gene id: 93934:ADAM12
uniprot id: A0A8C2SMV3
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:PDE4D
gene id: 93934:PDE4D
uniprot id: A0A8C2SNT6
uniprot id: A0A8C2SSV7
uniprot id: A0A8C2Y5A2
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:ATP5MG
gene id: 93934:ATP5MG
uniprot id: A0A8C2TEC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F0 domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion

93934:TRMT10C
gene id: 93934:TRMT10C
uniprot id: A0A8C2U1X3
names: Subcellular Location Annotation
messages: mitochondrion nucleoid

93934:LOC107306152
gene id: 93934:LOC107306152
uniprot id: A0A8C2T4S4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CTF/NF-I family.
messages: Binds DNA as a homodimer.
messages: Nucleus

93934:SEMA4G
gene id: 93934:SEMA4G
uniprot id: A0A8C2YGT1
names: Caution
names: Similarity
messages: Belongs to the semaphorin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:ADCY3
gene id: 93934:ADCY3
uniprot id: A0A8C2TRU4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
messages: Binds 2 magnesium ions per subunit. Is also active with manganese (in vitro).
messages: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
messages: Membrane

93934:CEPT1
gene id: 93934:CEPT1
uniprot id: A0A8C2TBN1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

93934:NDC80
gene id: 93934:NDC80
uniprot id: A0A8C2TA13
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

93934:LOC107309558
gene id: 93934:LOC107309558
uniprot id: A0A8C2TY96
names: Function
names: Subcellular Location Annotation
messages: Cadherins are calcium-dependent cell adhesion proteins.
messages: Cell membrane
messages: Membrane

93934:RXRG
gene id: 93934:RXRG
uniprot id: A0A8C2UID2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nuclear hormone receptor family. NR2 subfamily.
messages: Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
messages: Homodimer. Heterodimer; with a rar molecule.
messages: Nucleus
messages: Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (rars) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes.

93934:TMEM245
gene id: 93934:TMEM245
uniprot id: A0A8C2TSZ9
uniprot id: A0A8C2TT03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

93934:HSPB9
gene id: 93934:HSPB9
uniprot id: A0A8C2T0C0
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93934:ELF3
gene id: 93934:ELF3
uniprot id: A0A8C2T7F4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ETS family.
messages: Nucleus

93934:MYOZ2
gene id: 93934:MYOZ2
uniprot id: A0A8C2SWE7
names: Similarity
messages: Belongs to the myozenin family.

93934:C26H6orf89
gene id: 93934:C26H6orf89
uniprot id: A0A8C2Y9Q7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane

93934:HSPA9
gene id: 93934:HSPA9
uniprot id: A0A8C2TGN2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93934:SUPT6H
gene id: 93934:SUPT6H
uniprot id: A0A8C2TKV3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT6 family.
messages: Nucleus
messages: Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII).

93934:GSTK1
gene id: 93934:GSTK1
uniprot id: A0A8C2U4G3
names: Similarity
messages: Belongs to the GST superfamily. Kappa family.

93934:PTGER4
gene id: 93934:PTGER4
uniprot id: A0A8C2T642
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Cell membrane
messages: Interacts with FEM1A.
messages: Membrane
messages: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.

93934:ADIPOR2
gene id: 93934:ADIPOR2
uniprot id: A0A8C2U808
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIPOR family.
messages: Membrane

93934:EXOC7
gene id: 93934:EXOC7
uniprot id: A0A8C2UD81
names: Function
names: Similarity
messages: Belongs to the EXO70 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

93934:GCM2
gene id: 93934:GCM2
uniprot id: A0A8C2U277
uniprot id: A0A8C2U573
names: Subcellular Location Annotation
messages: Nucleus

93934:FGF8
gene id: 93934:FGF8
uniprot id: A0A8C2U988
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heparin-binding growth factors family.
messages: Secreted

93934:CPEB3
gene id: 93934:CPEB3
uniprot id: A0A8C2UD78
names: Similarity
messages: Belongs to the RRM CPEB family.

93934:KCNMA1
gene id: 93934:KCNMA1
uniprot id: A0A8C2YAV9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the potassium channel family. Calcium-activated (TC 1.A.1.3) subfamily. KCa1.1/KCNMA1 sub-subfamily.
messages: Membrane

93934:FGF10
gene id: 93934:FGF10
uniprot id: A0A8C2YAT3
names: Similarity
messages: Belongs to the heparin-binding growth factors family.

93934:TSPAN6
gene id: 93934:TSPAN6
uniprot id: A0A8C2TXW3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tetraspanin (TM4SF) family.
messages: Membrane

93934:MAPK9
gene id: 93934:MAPK9
uniprot id: A0A8C2T112
uniprot id: A0A8C2Y7E5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Cytoplasm
messages: Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, and thus regulates transcriptional activity.

93934:SLC27A4
gene id: 93934:SLC27A4
uniprot id: A0A8C2UBS9
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

93934:TBX22
gene id: 93934:TBX22
uniprot id: A0A8C2SV62
names: Caution
names: Subcellular Location Annotation
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

93934:DMAP1
gene id: 93934:DMAP1
uniprot id: A0A8C2YA59
names: Subcellular Location Annotation
messages: Nucleus

93934:SSX2IP
gene id: 93934:SSX2IP
uniprot id: A0A8C2TCI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ADIP family.
messages: adherens junction
messages: centriolar satellite

93934:MTM1
gene id: 93934:MTM1
uniprot id: A0A8C2SMQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.
messages: Cell membrane
messages: Late endosome
messages: filopodium
messages: ruffle
messages: sarcomere

93934:SFPQ
gene id: 93934:SFPQ
uniprot id: A0A8C2U1H1
names: Subcellular Location Annotation
messages: Nucleus speckle

93934:MED7
gene id: 93934:MED7
uniprot id: A0A8C2T8X2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

93934:ME1
gene id: 93934:ME1
uniprot id: A0A8C2SWH9
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

93934:MMP16
gene id: 93934:MMP16
uniprot id: A0A8C2SM01
names: Similarity
messages: Belongs to the peptidase M10A family.

93934:DUSP10
gene id: 93934:DUSP10
uniprot id: A0A8C2Y8I9
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

93934:OSBPL11
gene id: 93934:OSBPL11
uniprot id: A0A8C2UFK5
names: Similarity
messages: Belongs to the OSBP family.

93934:CDC42SE2
gene id: 93934:CDC42SE2
uniprot id: A0A8C2TB68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC42SE/SPEC family.
messages: Cell membrane
messages: Membrane
messages: cytoskeleton

93934:LOC107308445
gene id: 93934:LOC107308445
uniprot id: A0A8C2Y6N5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L6 tetraspanin family.
messages: Membrane

93934:CREBL2
gene id: 93934:CREBL2
uniprot id: A0A8C2TY50
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family. ATF subfamily.
messages: Nucleus

93934:NUP98
gene id: 93934:NUP98
uniprot id: A0A8C2T1I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

93934:VCP
gene id: 93934:VCP
uniprot id: A0A8C2T336
names: Similarity
messages: Belongs to the AAA ATPase family.

93934:TYMS
gene id: 93934:TYMS
uniprot id: A0A8C2Y9U9
names: Similarity
messages: Belongs to the thymidylate synthase family.

93934:CEP44
gene id: 93934:CEP44
uniprot id: A0A8C2TF39
names: Subcellular Location Annotation
messages: Midbody
messages: centriole
messages: spindle pole

93934:NKRF
gene id: 93934:NKRF
uniprot id: A0A8C2UAS1
names: Similarity
messages: Belongs to the CARF family.

93934:ANO10
gene id: 93934:ANO10
uniprot id: A0A8C2TL72
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anoctamin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93934:RPS26
gene id: 93934:RPS26
uniprot id: A0A8C2SPT0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

93934:ATP6AP1
gene id: 93934:ATP6AP1
uniprot id: A0A8C2TIS3
uniprot id: A0A8C2TNY3
names: Similarity
messages: Belongs to the vacuolar ATPase subunit S1 family.

93934:TEAD1
gene id: 93934:TEAD1
uniprot id: A0A8C2U722
uniprot id: A0A8C2UAE0
names: Subcellular Location Annotation
messages: Nucleus

93934:HYAL3
gene id: 93934:HYAL3
uniprot id: A0A8C2TJ89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 56 family.
messages: Cell membrane
messages: Early endosome
messages: Endoplasmic reticulum
messages: Endosome
messages: Membrane
messages: acrosome

93934:LOC107310447
gene id: 93934:LOC107310447
uniprot id: A0A8C2SPL4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 6c family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of 14 subunits. The complex is composed of a catalytic core of 3 subunits MT-CO1, MT-CO2 and MT-CO3, encoded in the mitochondrial DNA, and 11 supernumerary subunits COX4I, COX5A, COX5B, COX6A, COX6B, COX6C, COX7A, COX7B, COX7C, COX8 and NDUFA4, which are encoded in the nuclear genome. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with NADH-ubiquinone oxidoreductase (complex I, CI) and ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), resulting in different assemblies (supercomplex SCI(1)III(2)IV(1) and megacomplex MCI(2)III(2)IV(2)).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

93934:PPCS
gene id: 93934:PPCS
uniprot id: A0A8C2T426
names: Similarity
messages: Belongs to the PPC synthetase family.

93934:DCBLD1
gene id: 93934:DCBLD1
uniprot id: A0A8C2TA60
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93934:LOC107309811
gene id: 93934:LOC107309811
uniprot id: A0A8C2TRH7
names: Subcellular Location Annotation
messages: Nucleus

93934:RMI1
gene id: 93934:RMI1
uniprot id: A0A8C2TCC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RMI1 family.
messages: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.
messages: Nucleus

93934:HNRNPA3
gene id: 93934:HNRNPA3
uniprot id: A0A8C2U1W0
names: Subcellular Location Annotation
messages: Nucleus

93934:ATP5PD
gene id: 93934:ATP5PD
uniprot id: A0A8C2UIR8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion inner membrane

93934:GART
gene id: 93934:GART
uniprot id: A0A8C2T2V3
names: Similarity
messages: In the C-terminal section; belongs to the GART family.
messages: In the N-terminal section; belongs to the GARS family.
messages: In the central section; belongs to the AIR synthase family.

93934:LOC107324150
gene id: 93934:LOC107324150
uniprot id: A0A8C2YB61
names: Subcellular Location Annotation
messages: Membrane

93934:THRA
gene id: 93934:THRA
uniprot id: A0A8C2SUH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nuclear hormone receptor family. NR1 subfamily.
messages: Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
messages: Nucleus

93934:PYCR3
gene id: 93934:PYCR3
uniprot id: A0A8C2TEK9
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

93934:CEP170B
gene id: 93934:CEP170B
uniprot id: A0A8C2SRP3
uniprot id: A0A8C2SSU7
uniprot id: A0A8C2SSV9
uniprot id: A0A8C2STN8
uniprot id: A0A8C2Y5V3
names: Similarity
messages: Belongs to the CEP170 family.

93934:EXOC6
gene id: 93934:EXOC6
uniprot id: A0A8C2U7M0
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

93934:LOC107310130
gene id: 93934:LOC107310130
uniprot id: A0A8C2TEK2
names: Function
names: Subcellular Location Annotation
messages: Cell membrane
messages: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
messages: Membrane
messages: desmosome

93934:PDE4B
gene id: 93934:PDE4B
uniprot id: A0A8C2YD50
uniprot id: A0A8C2YD81
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family. PDE4 subfamily.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

93934:KCNF1
gene id: 93934:KCNF1
uniprot id: A0A8C2TIB2
names: Subcellular Location Annotation
messages: Membrane

93934:SH3BP5
gene id: 93934:SH3BP5
uniprot id: A0A8C2YC08
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SH3BP5 family.
messages: Cytoplasm
messages: Functions as guanine nucleotide exchange factor (GEF) for RAB11A.
messages: Interacts with GDP-bound and nucleotide-free forms of RAB11A.
messages: The N-terminal half of the protein mediates interaction with RAB11A and functions as guanine nucleotide exchange factor. Four long alpha-helices (interrupted by a central kink) assemble into coiled coils, giving rise to a 'V' shape.

93934:DR1
gene id: 93934:DR1
uniprot id: A0A8C2Y966
names: Similarity
messages: Belongs to the NC2 beta/DR1 family.

93934:SLC16A6
gene id: 93934:SLC16A6
uniprot id: A0A8C2UJS8
names: Subcellular Location Annotation
messages: Membrane

93934:DENND11
gene id: 93934:DENND11
uniprot id: A0A8C2UAR3
names: Similarity
messages: Belongs to the DENND11 family.

93934:GPR171
gene id: 93934:GPR171
uniprot id: A0A8C2U8X4
names: Similarity
messages: Belongs to the G-protein coupled receptor 1 family.

93934:VPS35
gene id: 93934:VPS35
uniprot id: A0A8C2YD15
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

93934:LZTFL1
gene id: 93934:LZTFL1
uniprot id: A0A8C2SYD3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LZTFL1 family.
messages: Cytoplasm
messages: Regulates ciliary localization of the BBSome complex. Together with the BBSome complex, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May play a role in neurite outgrowth. May have tumor suppressor function.
messages: Self-associates. Interacts with BBS9; the interaction mediates the association of LZTL1 with the BBsome complex and regulates BBSome ciliary trafficking.

93934:MPP6
gene id: 93934:MPP6
uniprot id: A0A8C2TNY6
names: Similarity
messages: Belongs to the MAGUK family.

93934:UNC5D
gene id: 93934:UNC5D
uniprot id: A0A8C2TTY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-5 family.
messages: Cell membrane
messages: Membrane
messages: Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding.

93934:LPIN1
gene id: 93934:LPIN1
uniprot id: A0A8C2TFQ5
uniprot id: A0A8C2THR7
uniprot id: A0A8C2TKN1
names: Similarity
messages: Belongs to the lipin family.

93934:SUPT4H1
gene id: 93934:SUPT4H1
uniprot id: A0A8C2Y6M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II.
messages: Nucleus

93934:GRIK2
gene id: 93934:GRIK2
uniprot id: A0A8C2TAR9
uniprot id: A0A8C2TD90
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
messages: Cell membrane
messages: Membrane
messages: Postsynaptic cell membrane
messages: Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.

93934:LOC107310851
gene id: 93934:LOC107310851
uniprot id: A0A8C2SN57
uniprot id: A0A8C2Y5F2
names: Similarity
messages: Belongs to the peptidase C2 family.

93934:TRDMT1
gene id: 93934:TRDMT1
uniprot id: A0A8C2T1K9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.

93934:LOC107315830
gene id: 93934:LOC107315830
uniprot id: A0A8C2TFE7
uniprot id: A0A8C2THY4
names: Function
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
messages: Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate.

93934:LOC107323344
gene id: 93934:LOC107323344
uniprot id: A0A8C2U7S2
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase A2 family.
messages: Binds 1 Ca(2+) ion per subunit.
messages: Secreted

93934:CPE
gene id: 93934:CPE
uniprot id: A0A8C2SQR2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M14 family.
messages: Membrane
messages: secretory vesicle membrane

93934:SLC11A2
gene id: 93934:SLC11A2
uniprot id: A0A8C2SXL8
uniprot id: A0A8C2Y6Y9
names: Similarity
messages: Belongs to the NRAMP family.

93934:PLEKHA8
gene id: 93934:PLEKHA8
uniprot id: A0A8C2TMR7
names: Subcellular Location Annotation
messages: Membrane
messages: trans-Golgi network membrane

93934:GUK1
gene id: 93934:GUK1
uniprot id: A0A8C2TGJ1
names: Similarity
messages: Belongs to the guanylate kinase family.

93934:OGDH
gene id: 93934:OGDH
uniprot id: A0A8C2THJ6
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

93934:SH3GLB1
gene id: 93934:SH3GLB1
uniprot id: A0A8C2T704
uniprot id: A0A8C2TA18
uniprot id: A0A8C2Y996
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the endophilin family.
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Mitochondrion outer membrane

93934:YES1
gene id: 93934:YES1
uniprot id: A0A8C2Y9N6
names: Similarity
messages: Belongs to the protein kinase superfamily. Tyr protein kinase family.

93934:FGD6
gene id: 93934:FGD6
uniprot id: A0A8C2SZ57
names: Subcellular Location Annotation
messages: cytoskeleton

93934:EML1
gene id: 93934:EML1
uniprot id: A0A8C2STV6
names: Function
names: Similarity
messages: Belongs to the WD repeat EMAP family.
messages: May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic.

93934:GSDMA
gene id: 93934:GSDMA
uniprot id: A0A8C2Y5W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gasdermin family.
messages: Cell membrane
messages: Membrane

93934:MTMR6
gene id: 93934:MTMR6
uniprot id: A0A8C2Y5C5
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

93934:LOC107324303
gene id: 93934:LOC107324303
uniprot id: A0A8C2T3A6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM45 family.
messages: Membrane

93934:CHST2
gene id: 93934:CHST2
uniprot id: A0A8C2YBB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily.
messages: Membrane

93934:LOXL1
gene id: 93934:LOXL1
uniprot id: A0A8C2T6M8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lysyl oxidase family.
messages: Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).
messages: The lysine tyrosylquinone cross-link (LTQ) is generated by condensation of the epsilon-amino group of a lysine with a topaquinone produced by oxidation of tyrosine.
messages: extracellular space

93934:SLC49A3
gene id: 93934:SLC49A3
uniprot id: A0A8C2TL95
names: Subcellular Location Annotation
messages: Membrane

93934:QRFPR
gene id: 93934:QRFPR
uniprot id: A0A8C2STE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 1 family.
messages: Membrane

93934:WARS2
gene id: 93934:WARS2
uniprot id: A0A8C2U524
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93934:LOC107319562
gene id: 93934:LOC107319562
uniprot id: A0A8C2T4A7
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the phosphoglycerate mutase family.

93934:LOC107308344
gene id: 93934:LOC107308344
uniprot id: A0A8C2SP35
names: Similarity
messages: Belongs to the TCP10 family.

93934:XYLB
gene id: 93934:XYLB
uniprot id: A0A8C2TFQ6
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis.

93934:POMC
gene id: 93934:POMC
uniprot id: F1T286
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the POMC family.
messages: Endogenous opiate.
messages: Secreted
messages: Stimulates the adrenal glands to release cortisol.

93934:MCOLN2
gene id: 93934:MCOLN2
uniprot id: A0A8C2Y942
names: Subcellular Location Annotation
messages: Endosome membrane
messages: Membrane

93934:TMEM38B
gene id: 93934:TMEM38B
uniprot id: A0A8C2TKT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM38 family.
messages: Membrane
messages: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores.

93934:EXOC3
gene id: 93934:EXOC3
uniprot id: A0A8C2Y8F9
names: Similarity
messages: Belongs to the SEC6 family.

93934:BYSL
gene id: 93934:BYSL
uniprot id: A0A8C2U8K5
names: Similarity
messages: Belongs to the bystin family.

93934:SRPX2
gene id: 93934:SRPX2
uniprot id: A0A8C2U110
names: Caution
names: Subcellular Location Annotation
messages: Cell surface
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Secreted
messages: Synapse

93934:DDX6
gene id: 93934:DDX6
uniprot id: A0A8C2TLV9
names: Similarity
messages: Belongs to the DEAD box helicase family.

93934:PPIF
gene id: 93934:PPIF
uniprot id: A0A8C2TF38
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93934:SPP2
gene id: 93934:SPP2
uniprot id: A0A8C2TMM5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Could coordinate an aspect of bone turnover.
messages: Secreted

93934:VDAC1
gene id: 93934:VDAC1
uniprot id: A0A8C2SXK1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic mitochondrial porin family.
messages: Cell membrane
messages: Membrane
messages: Membrane raft

93934:LOC107308931
gene id: 93934:LOC107308931
uniprot id: A0A8C2TLG3
uniprot id: A0A8C2YBN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Endosome membrane
messages: Late endosome membrane
messages: Lysosome membrane

93934:GCSH
gene id: 93934:GCSH
uniprot id: A0A8C2TXF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93934:PSMD13
gene id: 93934:PSMD13
uniprot id: A0A8C2TP47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the proteasome subunit S11 family.
messages: Component of the 19S proteasome regulatory particle complex. The 26S proteasome consists of a 20S core particle (CP) and two 19S regulatory subunits (RP). The regulatory particle is made of a lid composed of 9 subunits including PSMD13, a base containing 6 ATPases and few additional components.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair.

93934:CSRNP3
gene id: 93934:CSRNP3
uniprot id: A0A8C2UB54
uniprot id: A0A8C2UDP5
uniprot id: A0A8C2UGU5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AXUD1 family.
messages: Nucleus

93934:MYCL
gene id: 93934:MYCL
uniprot id: A0A8C2SXE6
names: Subcellular Location Annotation
names: Subunit
messages: Efficient DNA binding requires dimerization with another bHLH protein.
messages: Nucleus

93934:SLC35E4
gene id: 93934:SLC35E4
uniprot id: A0A8C2TWX8
names: Subcellular Location Annotation
messages: Membrane

93934:ARPC3
gene id: 93934:ARPC3
uniprot id: A0A8C2UEK8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

93934:LOC107321669
gene id: 93934:LOC107321669
uniprot id: A0A8C2YE07
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

93934:OTOP1
gene id: 93934:OTOP1
uniprot id: A0A8C2U845
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the otopetrin family.
messages: Cell membrane
messages: Membrane

93934:PPP4R3B
gene id: 93934:PPP4R3B
uniprot id: A0A8C2YEN6
names: Similarity
messages: Belongs to the SMEK family.

93934:GALNT16
gene id: 93934:GALNT16
uniprot id: A0A8C2TSW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
messages: Golgi apparatus membrane
messages: Membrane

93934:CCDC25
gene id: 93934:CCDC25
uniprot id: A0A8C2TLJ8
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CCDC25 family.
messages: Cell membrane
messages: Endomembrane system
messages: Interacts (via cytoplasmic region) with ILK.

93934:TRPC3
gene id: 93934:TRPC3
uniprot id: A0A8C2SWG8
names: Subcellular Location Annotation
messages: Membrane

93934:APC
gene id: 93934:APC
uniprot id: A0A8C2TGL9
names: Similarity
messages: Belongs to the adenomatous polyposis coli (APC) family.

93934:SLC4A10
gene id: 93934:SLC4A10
uniprot id: A0A8C2YD00
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anion exchanger (TC 2.A.31) family.
messages: Membrane

93934:LOC107311052
gene id: 93934:LOC107311052
uniprot id: A0A8C2SNG6
names: Similarity
messages: Belongs to the peptidase M14 family.