93221:RO07 RS14200
gene id: 93221:RO07_RS14200
uniprot id: A0A378ZD89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS04600
gene id: 93221:RO07_RS04600
uniprot id: A0A378Z2P6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the QueA family.
messages: Cytoplasm
messages: Monomer.
messages: Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).

93221:RO07 RS17320
gene id: 93221:RO07_RS17320
uniprot id: A0A378ZAR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Cell membrane

93221:RO07 RS17510
gene id: 93221:RO07_RS17510
uniprot id: A0A378Z9T5
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

93221:RO07 RS13050
gene id: 93221:RO07_RS13050
uniprot id: A0A379LRU5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS00080
gene id: 93221:RO07_RS00080
uniprot id: A0A378Z717
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

93221:RO07 RS14615
gene id: 93221:RO07_RS14615
uniprot id: A0A378ZBB9
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS19925
gene id: 93221:RO07_RS19925
uniprot id: A0A378ZA80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Membrane

93221:RO07 RS02460
gene id: 93221:RO07_RS02460
uniprot id: A0A378Z593
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
messages: Cytoplasm

93221:RO07 RS16755
gene id: 93221:RO07_RS16755
uniprot id: A0A378ZA83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS19165
gene id: 93221:RO07_RS19165
uniprot id: A0A378ZAC8
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS24410
gene id: 93221:RO07_RS24410
uniprot id: A0A378Z5W3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIS family. GmhA subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
messages: Cytoplasm
messages: Homotetramer.
messages: The reaction produces a racemic mixture of D-glycero-alpha-D-manno-heptose 7-phosphate and D-glycero-beta-D-manno-heptose 7-phosphate.

93221:RO07 RS16765
gene id: 93221:RO07_RS16765
uniprot id: A0A378ZA85
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

93221:RO07 RS02875
gene id: 93221:RO07_RS02875
uniprot id: A0A378Z3L7
names: Function
names: Similarity
messages: Belongs to the ribose 1,5-bisphosphokinase family.
messages: Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).

93221:RO07 RS23625
gene id: 93221:RO07_RS23625
uniprot id: A0A378Z7T6
names: Similarity
messages: Belongs to the CutA family.

93221:RO07 RS19480
gene id: 93221:RO07_RS19480
uniprot id: A0A378Z9R8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell inner membrane
messages: Cell membrane
messages: Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (UgpC), two transmembrane proteins (UgpA and UgpE) and a solute-binding protein (UgpB).

93221:RO07 RS14205
gene id: 93221:RO07_RS14205
uniprot id: A0A378ZCC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

93221:RO07 RS01310
gene id: 93221:RO07_RS01310
uniprot id: A0A378Z5B6
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS07355
gene id: 93221:RO07_RS07355
uniprot id: A0A378Z107
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS02375
gene id: 93221:RO07_RS02375
uniprot id: A0A378Z3Y9
names: Similarity
messages: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.

93221:RO07 RS09180
gene id: 93221:RO07_RS09180
uniprot id: A0A378Z1T8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS25020
gene id: 93221:RO07_RS25020
uniprot id: A0A378Z718
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhC family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.

93221:RO07 RS08245
gene id: 93221:RO07_RS08245
uniprot id: A0A378Z0F1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS19900
gene id: 93221:RO07_RS19900
uniprot id: A0A378Z8G4
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

93221:RO07 RS12780
gene id: 93221:RO07_RS12780
uniprot id: A0A379LRC2
names: Similarity
messages: Belongs to the FliN/MopA/SpaO family.

93221:RO07 RS13515
gene id: 93221:RO07_RS13515
uniprot id: A0A378ZC13
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS08085
gene id: 93221:RO07_RS08085
uniprot id: A0A378Z0I9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS19245
gene id: 93221:RO07_RS19245
uniprot id: A0A378Z8T4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15110
gene id: 93221:RO07_RS15110
uniprot id: A0A378ZD66
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93221:RO07 RS05670
gene id: 93221:RO07_RS05670
uniprot id: A0A378Z253
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS07550
gene id: 93221:RO07_RS07550
uniprot id: A0A378Z0V8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0126 family.
messages: Membrane

93221:RO07 RS16000
gene id: 93221:RO07_RS16000
uniprot id: A0A378ZCA0
names: Similarity
messages: Belongs to the citrate synthase family.

93221:RO07 RS23895
gene id: 93221:RO07_RS23895
uniprot id: A0A378Z647
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93221:RO07 RS14095
gene id: 93221:RO07_RS14095
uniprot id: A0A378ZD74
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS18515
gene id: 93221:RO07_RS18515
uniprot id: A0A378ZAA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

93221:RO07 RS23750
gene id: 93221:RO07_RS23750
uniprot id: A0A378Z682
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL2 family.
messages: One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.

93221:RO07 RS09845
gene id: 93221:RO07_RS09845
uniprot id: A0A378Z1I7
names: Similarity
messages: Belongs to the citrate synthase family.

93221:RO07 RS04925
gene id: 93221:RO07_RS04925
uniprot id: A0A378Z4B7
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

93221:RO07 RS24490
gene id: 93221:RO07_RS24490
uniprot id: A0A378Z5T6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS13210
gene id: 93221:RO07_RS13210
uniprot id: A0A378ZCX3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS17365
gene id: 93221:RO07_RS17365
uniprot id: A0A378Z9W5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS03095
gene id: 93221:RO07_RS03095
uniprot id: A0A378Z546
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93221:RO07 RS16910
gene id: 93221:RO07_RS16910
uniprot id: A0A378ZAZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS14235
gene id: 93221:RO07_RS14235
uniprot id: A0A378ZBM9
names: Similarity
messages: Belongs to the YjdM family.

93221:RO07 RS24825
gene id: 93221:RO07_RS24825
uniprot id: A0A378Z6V9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

93221:RO07 RS00005
gene id: 93221:RO07_RS00005
uniprot id: A0A378Z5A8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DnaA family.
messages: Cytoplasm
messages: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.

93221:RO07 RS10290
gene id: 93221:RO07_RS10290
uniprot id: A0A378Z0A8
names: Caution
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. RlmN family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.
messages: Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity.

93221:RO07 RS14700
gene id: 93221:RO07_RS14700
uniprot id: A0A378ZCZ6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS02685
gene id: 93221:RO07_RS02685
uniprot id: A0A378Z3P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.
messages: This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.

93221:RO07 RS21195
gene id: 93221:RO07_RS21195
uniprot id: A0A378Z9P0
names: Cofactor
names: Function
messages: Binds 2 [4Fe-4S] clusters.
messages: Component of a complex that catalyzes the oxidation of glycolate to glyoxylate.

93221:RO07 RS04695
gene id: 93221:RO07_RS04695
uniprot id: A0A378Z2M8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0114 family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS06680
gene id: 93221:RO07_RS06680
uniprot id: A0A378Z2D0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytidylate kinase family. Type 1 subfamily.
messages: Cytoplasm

93221:RO07 RS21375
gene id: 93221:RO07_RS21375
uniprot id: A0A378Z7K5
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

93221:RO07 RS13905
gene id: 93221:RO07_RS13905
uniprot id: A0A378ZBQ0
names: Function
names: Similarity
messages: Belongs to the thymidylate kinase family.
messages: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

93221:RO07 RS20330
gene id: 93221:RO07_RS20330
uniprot id: A0A378ZA04
names: Function
names: Induction
names: Similarity
messages: Acts as a chaperone.
messages: Belongs to the heat shock protein 70 family.
messages: By stress conditions e.g. heat shock.

93221:RO07 RS00615
gene id: 93221:RO07_RS00615
uniprot id: A0A378Z4Z0
names: Cofactor
messages: Binds 1 Fe(2+) ion per subunit.

93221:RO07 RS03210
gene id: 93221:RO07_RS03210
uniprot id: A0A378Z4T5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS09660
gene id: 93221:RO07_RS09660
uniprot id: A0A378YZM0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 4L family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS10935
gene id: 93221:RO07_RS10935
uniprot id: A0A378Z015
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.

93221:RO07 RS25105
gene id: 93221:RO07_RS25105
uniprot id: A0A378Z666
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the calycin superfamily. Lipocalin family.
messages: Cell outer membrane
messages: Homodimer.
messages: Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids.

93221:RO07 RS03220
gene id: 93221:RO07_RS03220
uniprot id: A0A378Z3E3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17440
gene id: 93221:RO07_RS17440
uniprot id: A0A378ZBL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LysR transcriptional regulatory family.
messages: Cytoplasm

93221:RO07 RS07055
gene id: 93221:RO07_RS07055
uniprot id: A0A378Z1D2
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

93221:RO07 RS01105
gene id: 93221:RO07_RS01105
uniprot id: A0A378Z4N5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22365
gene id: 93221:RO07_RS22365
uniprot id: A0A378Z7S3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL21 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L20.
messages: This protein binds to 23S rRNA in the presence of protein L20.

93221:RO07 RS20975
gene id: 93221:RO07_RS20975
uniprot id: A0A378Z8J9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP synthase family.
messages: Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
messages: Cytoplasm
messages: Homooctamer; tetramer of dimers.

93221:RO07 RS09840
gene id: 93221:RO07_RS09840
uniprot id: A0A378Z1F9
names: Similarity
messages: Belongs to the SdhE FAD assembly factor family.

93221:RO07 RS06540
gene id: 93221:RO07_RS06540
uniprot id: A0A378Z3N9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20125
gene id: 93221:RO07_RS20125
uniprot id: A0A378Z9S4
names: Similarity
messages: Belongs to the UPF0162 family.

93221:RO07 RS18900
gene id: 93221:RO07_RS18900
uniprot id: A0A378Z9S0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS14320
gene id: 93221:RO07_RS14320
uniprot id: A0A378ZBJ1
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A peripheral cell membrane enzyme that catalyzes the oxidative decarboxylation of pyruvate to form acetate and CO(2). It channels electrons from the cytoplasm to the respiratory chain at the cell membrane via ubiquinone.
messages: Belongs to the TPP enzyme family.
messages: Binds 1 FAD per subunit.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Cell membrane
messages: Has 4 domains; the Pyr domain which binds the pyrimidine moiety of the thiamine pyrophosphate cofactor, the FAD-binding domain, the PP-binding domain which binds the pyrophosphate portion of thiamine pyrophosphate and the C-terminal membrane binding region. The C-terminus is held closely against the rest of the protein and covers the active site; during activation it unfolds from the rest of the protein and forms an amphipathic helix upon membrane binding, exposing the active site.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: The C-terminus inhibits activity; it has to move for the enzyme to be active. Activated by lipid-binding, which occurs via the C-terminus.

93221:RO07 RS03335
gene id: 93221:RO07_RS03335
uniprot id: A0A378Z3C8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10170
gene id: 93221:RO07_RS10170
uniprot id: A0A378Z103
names: Function
names: Similarity
messages: Belongs to the RecR family.
messages: May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.

93221:RO07 RS19520
gene id: 93221:RO07_RS19520
uniprot id: A0A378ZAF3
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.

93221:RO07 RS20610
gene id: 93221:RO07_RS20610
uniprot id: A0A378Z820
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

93221:RO07 RS00215
gene id: 93221:RO07_RS00215
uniprot id: A0A378Z5W8
names: Similarity
messages: Belongs to the FrmR/RcnR family.

93221:RO07 RS17650
gene id: 93221:RO07_RS17650
uniprot id: A0A378Z9P4
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS10795
gene id: 93221:RO07_RS10795
uniprot id: A0A378YZ96
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

93221:RO07 RS20340
gene id: 93221:RO07_RS20340
uniprot id: A0A378Z9A2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GrpE family.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.

93221:RO07 RS00225
gene id: 93221:RO07_RS00225
uniprot id: A0A378Z754
names: Function
names: Similarity
messages: Belongs to the UPF0677 family.
messages: Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.

93221:RO07 RS05580
gene id: 93221:RO07_RS05580
uniprot id: A0A378Z2X5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24770
gene id: 93221:RO07_RS24770
uniprot id: A0A378Z6J6
names: Similarity
messages: Belongs to the type III secretion exporter family.

93221:RO07 RS16115
gene id: 93221:RO07_RS16115
uniprot id: A0A378ZAJ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS14325
gene id: 93221:RO07_RS14325
uniprot id: A0A378ZBH6
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

93221:RO07 RS15205
gene id: 93221:RO07_RS15205
uniprot id: A0A378ZBW8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the chorismate synthase family.
messages: Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
messages: Homotetramer.
messages: Reduced FMN (FMNH(2)).

93221:RO07 RS23900
gene id: 93221:RO07_RS23900
uniprot id: A0A378Z649
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL12 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.
messages: Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.

93221:RO07 RS04580
gene id: 93221:RO07_RS04580
uniprot id: A0A378Z3L6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecF subfamily.
messages: Cell membrane
messages: Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

93221:RO07 RS15350
gene id: 93221:RO07_RS15350
uniprot id: A0A378ZCN6
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS01295
gene id: 93221:RO07_RS01295
uniprot id: A0A378Z4J9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease beta subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

93221:RO07 RS04280
gene id: 93221:RO07_RS04280
uniprot id: A0A378Z3R1
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

93221:RO07 RS17755
gene id: 93221:RO07_RS17755
uniprot id: A0A378Z9N4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the shikimate kinase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS16880
gene id: 93221:RO07_RS16880
uniprot id: A0A378ZBU0
names: Similarity
messages: Belongs to the GppA/Ppx family.

93221:RO07 RS07140
gene id: 93221:RO07_RS07140
uniprot id: A0A378Z276
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00735
gene id: 93221:RO07_RS00735
uniprot id: A0A378Z663
names: Caution
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS08130
gene id: 93221:RO07_RS08130
uniprot id: A0A378Z0I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23685
gene id: 93221:RO07_RS23685
uniprot id: A0A378Z756
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.
messages: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.

93221:RO07 RS18705
gene id: 93221:RO07_RS18705
uniprot id: A0A378ZAW2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MoaC family.
messages: Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).
messages: Homohexamer; trimer of dimers.

93221:RO07 RS05600
gene id: 93221:RO07_RS05600
uniprot id: A0A378Z3Y7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS03575
gene id: 93221:RO07_RS03575
uniprot id: A0A378Z372
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23715
gene id: 93221:RO07_RS23715
uniprot id: A0A378Z696
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL14 family.
messages: Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.
messages: Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.

93221:RO07 RS09125
gene id: 93221:RO07_RS09125
uniprot id: A0A378Z236
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS19575
gene id: 93221:RO07_RS19575
uniprot id: A0A378Z9F1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS23330
gene id: 93221:RO07_RS23330
uniprot id: A0A378Z8A3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatB family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93221:RO07 RS08975
gene id: 93221:RO07_RS08975
uniprot id: A0A378YZZ7
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.
messages: This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.

93221:RO07 RS24845
gene id: 93221:RO07_RS24845
uniprot id: A0A378Z6B5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

93221:RO07 RS23725
gene id: 93221:RO07_RS23725
uniprot id: A0A378Z7R4
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

93221:RO07 RS16955
gene id: 93221:RO07_RS16955
uniprot id: A0A378ZA43
names: Function
names: Similarity
messages: Belongs to the GreA/GreB family.
messages: Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

93221:RO07 RS16050
gene id: 93221:RO07_RS16050
uniprot id: A0A378ZBD6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS04665
gene id: 93221:RO07_RS04665
uniprot id: A0A378Z498
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

93221:RO07 RS19445
gene id: 93221:RO07_RS19445
uniprot id: A0A378Z8P7
names: Similarity
messages: Belongs to the GARS family.

93221:RO07 RS22665
gene id: 93221:RO07_RS22665
uniprot id: A0A378Z7S6
names: Similarity
messages: Belongs to the pirin family.

93221:RO07 RS02025
gene id: 93221:RO07_RS02025
uniprot id: A0A378Z4Y5
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

93221:RO07 RS23615
gene id: 93221:RO07_RS23615
uniprot id: A0A378Z6B7
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Homooctamer.

93221:RO07 RS09870
gene id: 93221:RO07_RS09870
uniprot id: A0A378YZR5
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS12585
gene id: 93221:RO07_RS12585
uniprot id: A0A378YY03
names: Similarity
messages: Belongs to the VgrG protein family.

93221:RO07 RS21740
gene id: 93221:RO07_RS21740
uniprot id: A0A378Z876
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

93221:RO07 RS17175
gene id: 93221:RO07_RS17175
uniprot id: A0A378ZC46
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS15995
gene id: 93221:RO07_RS15995
uniprot id: A0A378ZC40
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.

93221:RO07 RS07555
gene id: 93221:RO07_RS07555
uniprot id: A0A378Z1T9
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS21885
gene id: 93221:RO07_RS21885
uniprot id: A0A378Z8T1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS03680
gene id: 93221:RO07_RS03680
uniprot id: A0A378Z3Y3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS14060
gene id: 93221:RO07_RS14060
uniprot id: A0A378ZCS3
names: Function
names: Similarity
names: Subunit
messages: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
messages: Belongs to the ClpX chaperone family.
messages: Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.

93221:RO07 RS21025
gene id: 93221:RO07_RS21025
uniprot id: A0A378Z8I9
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS09765
gene id: 93221:RO07_RS09765
uniprot id: A0A378YZT7
names: Function
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.

93221:RO07 RS06575
gene id: 93221:RO07_RS06575
uniprot id: A0A378Z1N1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS20700
gene id: 93221:RO07_RS20700
uniprot id: A0A378Z7Y8
names: Similarity
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.

93221:RO07 RS10465
gene id: 93221:RO07_RS10465
uniprot id: A0A378Z097
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
messages: Cell membrane
messages: Monomer.

93221:RO07 RS01815
gene id: 93221:RO07_RS01815
uniprot id: A0A378Z4A1
names: Similarity
messages: Belongs to the pirin family.

93221:RO07 RS12765
gene id: 93221:RO07_RS12765
uniprot id: A0A379LRP5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS06165
gene id: 93221:RO07_RS06165
uniprot id: A0A378Z1P3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiD family.
messages: Binds 1 prenylated FMN (prenyl-FMN) per subunit.
messages: Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
messages: Cell membrane
messages: Homohexamer.

93221:RO07 RS24240
gene id: 93221:RO07_RS24240
uniprot id: A0A378Z5Y6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21450
gene id: 93221:RO07_RS21450
uniprot id: A0A378Z9D4
names: Similarity
messages: Belongs to the HIBADH-related family.

93221:RO07 RS09525
gene id: 93221:RO07_RS09525
uniprot id: A0A378Z1L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS24565
gene id: 93221:RO07_RS24565
uniprot id: A0A378Z7R0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the helicase family. UvrD subfamily.
messages: Homodimer.
messages: Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.

93221:RO07 RS13160
gene id: 93221:RO07_RS13160
uniprot id: A0A378ZDV6
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.

93221:RO07 RS06225
gene id: 93221:RO07_RS06225
uniprot id: A0A378Z2L0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24545
gene id: 93221:RO07_RS24545
uniprot id: A0A378Z5S8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvP family.
messages: The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93221:RO07 RS20215
gene id: 93221:RO07_RS20215
uniprot id: A0A378Z8A0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS19780
gene id: 93221:RO07_RS19780
uniprot id: A0A378Z9A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

93221:RO07 RS11470
gene id: 93221:RO07_RS11470
uniprot id: A0A378Z0I7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.
messages: Belongs to the EF-Ts family.
messages: Cytoplasm

93221:RO07 RS21940
gene id: 93221:RO07_RS21940
uniprot id: A0A378Z937
names: Similarity
messages: Belongs to the bacterial solute-binding protein 9 family.

93221:RO07 RS09335
gene id: 93221:RO07_RS09335
uniprot id: A0A378YZT2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
messages: Cytoplasm
messages: Homodimer. Forms a heterotetramer with IscU, interacts with other sulfur acceptors.
messages: Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.

93221:RO07 RS16235
gene id: 93221:RO07_RS16235
uniprot id: A0A378ZAG8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 Fe(2+) ion per subunit.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.

93221:RO07 RS06095
gene id: 93221:RO07_RS06095
uniprot id: A0A378Z3N5
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

93221:RO07 RS05835
gene id: 93221:RO07_RS05835
uniprot id: A0A378Z420
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

93221:RO07 RS22880
gene id: 93221:RO07_RS22880
uniprot id: A0A378Z6R1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS03515
gene id: 93221:RO07_RS03515
uniprot id: A0A378Z4M1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

93221:RO07 RS14415
gene id: 93221:RO07_RS14415
uniprot id: A0A378ZBI5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

93221:RO07 RS12755
gene id: 93221:RO07_RS12755
uniprot id: A0A379LRG6
names: Similarity
messages: Belongs to the LcrH/SycD chaperone family.

93221:RO07 RS00235
gene id: 93221:RO07_RS00235
uniprot id: A0A378Z6Y9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04545
gene id: 93221:RO07_RS04545
uniprot id: A0A378Z2L2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliR/MopE/SpaR family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS14110
gene id: 93221:RO07_RS14110
uniprot id: A0A378ZCE6
names: Function
names: Similarity
messages: Belongs to the MinE family.
messages: Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.

93221:RO07 RS16625
gene id: 93221:RO07_RS16625
uniprot id: A0A378ZBY0
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS08780
gene id: 93221:RO07_RS08780
uniprot id: A0A378Z045
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

93221:RO07 RS13760
gene id: 93221:RO07_RS13760
uniprot id: A0A378ZBU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

93221:RO07 RS04815
gene id: 93221:RO07_RS04815
uniprot id: A0A378Z4M7
names: Similarity
messages: Belongs to the MotB family.

93221:RO07 RS02010
gene id: 93221:RO07_RS02010
uniprot id: A0A378Z459
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS04320
gene id: 93221:RO07_RS04320
uniprot id: A0A378Z4G1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.
messages: An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
messages: Belongs to the DTD family.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS22690
gene id: 93221:RO07_RS22690
uniprot id: A0A378Z7K7
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

93221:RO07 RS03115
gene id: 93221:RO07_RS03115
uniprot id: A0A378Z3G9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS20515
gene id: 93221:RO07_RS20515
uniprot id: A0A378Z8T5
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

93221:RO07 RS15550
gene id: 93221:RO07_RS15550
uniprot id: A0A378ZCJ4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNase PH family.
messages: Homohexameric ring arranged as a trimer of dimers.
messages: Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.

93221:RO07 RS01585
gene id: 93221:RO07_RS01585
uniprot id: A0A378Z5A4
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93221:RO07 RS10765
gene id: 93221:RO07_RS10765
uniprot id: A0A378Z0X6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Cytoplasm
messages: Oligomer of 12 subunits arranged in the form of two hexagons.

93221:RO07 RS01245
gene id: 93221:RO07_RS01245
uniprot id: A0A378Z4K7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS21275
gene id: 93221:RO07_RS21275
uniprot id: A0A378Z7N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93221:RO07 RS05480
gene id: 93221:RO07_RS05480
uniprot id: A0A378Z342
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

93221:RO07 RS20395
gene id: 93221:RO07_RS20395
uniprot id: A0A378Z850
names: Similarity
messages: Belongs to the peptidase U62 family.

93221:RO07 RS18645
gene id: 93221:RO07_RS18645
uniprot id: A0A378ZB64
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
messages: One is catalytic and the other provides a structural contribution.

93221:RO07 RS02050
gene id: 93221:RO07_RS02050
uniprot id: A0A378Z514
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS08925
gene id: 93221:RO07_RS08925
uniprot id: A0A378Z005
names: Function
names: Similarity
messages: Belongs to the DadA oxidoreductase family.
messages: Oxidative deamination of D-amino acids.

93221:RO07 RS16980
gene id: 93221:RO07_RS16980
uniprot id: A0A378ZBS9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23835
gene id: 93221:RO07_RS23835
uniprot id: A0A378Z721
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93221:RO07 RS04540
gene id: 93221:RO07_RS04540
uniprot id: A0A378Z2M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

93221:RO07 RS10390
gene id: 93221:RO07_RS10390
uniprot id: A0A378Z089
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

93221:RO07 RS03525
gene id: 93221:RO07_RS03525
uniprot id: A0A378Z380
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93221:RO07 RS20965
gene id: 93221:RO07_RS20965
uniprot id: A0A378Z7S9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.
messages: Cytoplasm
messages: Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides.

93221:RO07 RS00205
gene id: 93221:RO07_RS00205
uniprot id: A0A378Z560
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Membrane

93221:RO07 RS14665
gene id: 93221:RO07_RS14665
uniprot id: A0A378ZBB4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HAK/KUP transporter (TC 2.A.72) family.
messages: Cell membrane
messages: Membrane
messages: Transport of potassium into the cell.

93221:RO07 RS18370
gene id: 93221:RO07_RS18370
uniprot id: A0A378Z998
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TER reductase family.
messages: Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP).
messages: Monomer.

93221:RO07 RS24000
gene id: 93221:RO07_RS24000
uniprot id: A0A378Z644
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS03345
gene id: 93221:RO07_RS03345
uniprot id: A0A378Z3A8
names: Similarity
messages: Belongs to the arginase family.

93221:RO07 RS20170
gene id: 93221:RO07_RS20170
uniprot id: A0A378ZA87
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PlsY family.
messages: Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.
messages: Cell membrane
messages: Probably interacts with PlsX.

93221:RO07 RS17110
gene id: 93221:RO07_RS17110
uniprot id: A0A378ZAV4
names: Function
names: Subunit
messages: DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex.
messages: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

93221:RO07 RS20010
gene id: 93221:RO07_RS20010
uniprot id: A0A378Z941
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10035
gene id: 93221:RO07_RS10035
uniprot id: A0A378Z1L1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

93221:RO07 RS19835
gene id: 93221:RO07_RS19835
uniprot id: A0A378Z9J1
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

93221:RO07 RS11445
gene id: 93221:RO07_RS11445
uniprot id: A0A378YYN4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the polypeptide deformylase family.
messages: Binds 1 Fe(2+) ion.
messages: Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.

93221:RO07 RS07670
gene id: 93221:RO07_RS07670
uniprot id: A0A378Z2F1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

93221:RO07 RS11220
gene id: 93221:RO07_RS11220
uniprot id: A0A378Z0N7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS10255
gene id: 93221:RO07_RS10255
uniprot id: A0A378Z173
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.
messages: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
messages: Cytoplasm

93221:RO07 RS18050
gene id: 93221:RO07_RS18050
uniprot id: A0A378Z9H4
names: Similarity
messages: Belongs to the YciI family.

93221:RO07 RS00315
gene id: 93221:RO07_RS00315
uniprot id: A0A378Z5U9
names: Function
names: Similarity
messages: Belongs to the PINc/VapC protein family.
messages: Toxic component of a toxin-antitoxin (TA) system. An RNase.

93221:RO07 RS13275
gene id: 93221:RO07_RS13275
uniprot id: A0A378ZC61
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

93221:RO07 RS01695
gene id: 93221:RO07_RS01695
uniprot id: A0A378Z5N7
names: Similarity
messages: Belongs to the GST superfamily.

93221:RO07 RS11810
gene id: 93221:RO07_RS11810
uniprot id: A0A378YYG8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13880
gene id: 93221:RO07_RS13880
uniprot id: A0A378ZDV3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the glycosyltransferase 20 family.
messages: Homotetramer.
messages: Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor.

93221:RO07 RS13830
gene id: 93221:RO07_RS13830
uniprot id: A0A378ZDW4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

93221:RO07 RS21580
gene id: 93221:RO07_RS21580
uniprot id: A0A378Z8Y5
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS12960
gene id: 93221:RO07_RS12960
uniprot id: A0A379LQU5
names: Similarity
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.

93221:RO07 RS07505
gene id: 93221:RO07_RS07505
uniprot id: A0A378Z0X0
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS05515
gene id: 93221:RO07_RS05515
uniprot id: A0A378Z487
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

93221:RO07 RS09780
gene id: 93221:RO07_RS09780
uniprot id: A0A378Z1R2
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGMT family.
messages: Cytoplasm
messages: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
messages: This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.

93221:RO07 RS06715
gene id: 93221:RO07_RS06715
uniprot id: A0A378Z1F8
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily.
messages: Binds 1 NADP(+) per subunit.
messages: Catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose.
messages: Contains a large N-terminal NADP-binding domain, and a smaller C-terminal substrate-binding domain.
messages: Homopentamer.

93221:RO07 RS03775
gene id: 93221:RO07_RS03775
uniprot id: A0A378Z343
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22165
gene id: 93221:RO07_RS22165
uniprot id: A0A378Z755
names: Caution
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the thiamine-monophosphate kinase family.
messages: Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.

93221:RO07 RS02515
gene id: 93221:RO07_RS02515
uniprot id: A0A378Z3V6
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

93221:RO07 RS02380
gene id: 93221:RO07_RS02380
uniprot id: A0A378Z4Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiK family.
messages: Cytoplasm
messages: Required for efficient ubiquinone (coenzyme Q) biosynthesis. UbiK is probably an accessory factor of Ubi enzymes and facilitates ubiquinone biosynthesis by acting as an assembly factor, a targeting factor, or both.

93221:RO07 RS08625
gene id: 93221:RO07_RS08625
uniprot id: A0A378Z171
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS07920
gene id: 93221:RO07_RS07920
uniprot id: A0A378Z2A1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09640
gene id: 93221:RO07_RS09640
uniprot id: A0A378Z1M3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the complex I 75 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS05735
gene id: 93221:RO07_RS05735
uniprot id: A0A378Z442
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS14165
gene id: 93221:RO07_RS14165
uniprot id: A0A378ZBK7
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

93221:RO07 RS22650
gene id: 93221:RO07_RS22650
uniprot id: A0A378Z8W4
names: Similarity
messages: Belongs to the TrpC family.

93221:RO07 RS17330
gene id: 93221:RO07_RS17330
uniprot id: A0A378ZC09
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

93221:RO07 RS19885
gene id: 93221:RO07_RS19885
uniprot id: A0A378Z9I1
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93221:RO07 RS21735
gene id: 93221:RO07_RS21735
uniprot id: A0A378Z974
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterotetramer of two alpha and two beta subunits.
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

93221:RO07 RS16900
gene id: 93221:RO07_RS16900
uniprot id: A0A378ZA48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PhoU family.
messages: Cytoplasm
messages: Homodimer.
messages: Plays a role in the regulation of phosphate uptake.

93221:RO07 RS02805
gene id: 93221:RO07_RS02805
uniprot id: A0A378Z5K0
names: Similarity
messages: Belongs to the phosphate/phosphite/phosphonate binding protein family.

93221:RO07 RS20520
gene id: 93221:RO07_RS20520
uniprot id: A0A378Z846
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93221:RO07 RS11560
gene id: 93221:RO07_RS11560
uniprot id: A0A378YYK8
names: Similarity
messages: Belongs to the band 7/mec-2 family.

93221:RO07 RS24970
gene id: 93221:RO07_RS24970
uniprot id: A0A378Z7C4
names: Function
names: Similarity
messages: Belongs to the CheD family.
messages: Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.

93221:RO07 RS10685
gene id: 93221:RO07_RS10685
uniprot id: A0A378Z027
names: Function
names: Similarity
messages: Belongs to the esterase D family.
messages: Serine hydrolase involved in the detoxification of formaldehyde.

93221:RO07 RS06865
gene id: 93221:RO07_RS06865
uniprot id: A0A378Z1B1
names: Function
names: Similarity
messages: Belongs to the CobB/CobQ family. CobQ subfamily.
messages: Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation.

93221:RO07 RS02725
gene id: 93221:RO07_RS02725
uniprot id: A0A378Z3P9
names: Function
names: Similarity
messages: Belongs to the RapZ-like family.
messages: Displays ATPase and GTPase activities.

93221:RO07 RS01380
gene id: 93221:RO07_RS01380
uniprot id: A0A378Z5E1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS17675
gene id: 93221:RO07_RS17675
uniprot id: A0A378ZBT7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS03000
gene id: 93221:RO07_RS03000
uniprot id: A0A378Z5F8
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS16310
gene id: 93221:RO07_RS16310
uniprot id: A0A378ZCJ2
names: Similarity
messages: Belongs to the pseudomonas-type ThrB family.

93221:RO07 RS11440
gene id: 93221:RO07_RS11440
uniprot id: A0A378YYP6
names: Caution
names: Function
names: Similarity
messages: Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
messages: DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS24975
gene id: 93221:RO07_RS24975
uniprot id: A0A378Z6F4
names: Function
messages: Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.

93221:RO07 RS14805
gene id: 93221:RO07_RS14805
uniprot id: A0A378ZC16
names: Cofactor
names: Function
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Binds 1 FAD per subunit.
messages: Binds 1 FMN per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.

93221:RO07 RS16550
gene id: 93221:RO07_RS16550
uniprot id: A0A378ZAB9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06020
gene id: 93221:RO07_RS06020
uniprot id: A0A378Z1Z2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS12590
gene id: 93221:RO07_RS12590
uniprot id: A0A378YY04
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

93221:RO07 RS21645
gene id: 93221:RO07_RS21645
uniprot id: A0A378Z8J0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24860
gene id: 93221:RO07_RS24860
uniprot id: A0A378Z750
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space.
messages: In the C-terminal section; belongs to the glycosyl hydrolase 73 family.
messages: In the N-terminal section; belongs to the FlgJ family.
messages: Periplasm

93221:RO07 RS08170
gene id: 93221:RO07_RS08170
uniprot id: A0A378Z1J8
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

93221:RO07 RS09655
gene id: 93221:RO07_RS09655
uniprot id: A0A378YZM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 6 family.
messages: Cell membrane
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS00730
gene id: 93221:RO07_RS00730
uniprot id: A0A378Z5R7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48B family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Membrane

93221:RO07 RS09620
gene id: 93221:RO07_RS09620
uniprot id: A0A378Z0N0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 30 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS00135
gene id: 93221:RO07_RS00135
uniprot id: A0A378Z639
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS25380
gene id: 93221:RO07_RS25380
uniprot id: A0A378Z6J8
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
messages: Binds 1 potassium ion per subunit.
messages: Cytoplasm
messages: Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS17095
gene id: 93221:RO07_RS17095
uniprot id: A0A378ZA05
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Monomer.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

93221:RO07 RS18935
gene id: 93221:RO07_RS18935
uniprot id: A0A378ZAZ7
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

93221:RO07 RS15985
gene id: 93221:RO07_RS15985
uniprot id: A0A378ZAM8
names: Similarity
messages: Belongs to the PrpD family.

93221:RO07 RS25045
gene id: 93221:RO07_RS25045
uniprot id: A0A378Z5H1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

93221:RO07 RS00640
gene id: 93221:RO07_RS00640
uniprot id: A0A378Z681
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS19970
gene id: 93221:RO07_RS19970
uniprot id: A0A378Z9V3
names: Caution
names: Function
names: Similarity
messages: Belongs to the dUTPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

93221:RO07 RS06100
gene id: 93221:RO07_RS06100
uniprot id: A0A378Z2S0
names: Similarity
messages: Belongs to the UPF0337 (CsbD) family.

93221:RO07 RS07755
gene id: 93221:RO07_RS07755
uniprot id: A0A378Z2P8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

93221:RO07 RS04960
gene id: 93221:RO07_RS04960
uniprot id: A0A378Z2B8
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS22520
gene id: 93221:RO07_RS22520
uniprot id: A0A378Z7P6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol during ubiquinone biosynthesis.
messages: Cell membrane

93221:RO07 RS25110
gene id: 93221:RO07_RS25110
uniprot id: A0A378Z5G4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.

93221:RO07 RS12705
gene id: 93221:RO07_RS12705
uniprot id: A0A379LPL8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS23610
gene id: 93221:RO07_RS23610
uniprot id: A0A378Z723
names: Function
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
messages: Necessary for normal cell division and for the maintenance of normal septation.

93221:RO07 RS05840
gene id: 93221:RO07_RS05840
uniprot id: A0A378Z3Q5
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

93221:RO07 RS21220
gene id: 93221:RO07_RS21220
uniprot id: A0A378Z7N8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility.
messages: Bacterial flagellum basal body
messages: Belongs to the YcgR family.
messages: Monomer. Interacts with the flagellar basal bodies.

93221:RO07 RS04425
gene id: 93221:RO07_RS04425
uniprot id: A0A378Z4L3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22075
gene id: 93221:RO07_RS22075
uniprot id: A0A378Z7A3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gamma-glutamyl phosphate reductase family.
messages: Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.
messages: Cytoplasm

93221:RO07 RS04345
gene id: 93221:RO07_RS04345
uniprot id: A0A378Z2P9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RuvC family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

93221:RO07 RS12095
gene id: 93221:RO07_RS12095
uniprot id: A0A378YYA9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09785
gene id: 93221:RO07_RS09785
uniprot id: A0A378Z1G6
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

93221:RO07 RS13540
gene id: 93221:RO07_RS13540
uniprot id: A0A378ZDI1
names: Subcellular Location Annotation
messages: Periplasm

93221:RO07 RS06180
gene id: 93221:RO07_RS06180
uniprot id: A0A378Z1N8
names: Function
names: Similarity
messages: Belongs to the NusB family.
messages: Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.

93221:RO07 RS00475
gene id: 93221:RO07_RS00475
uniprot id: A0A378Z6K4
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

93221:RO07 RS02750
gene id: 93221:RO07_RS02750
uniprot id: A0A378Z5B3
names: Function
names: Similarity
messages: Belongs to the sigma-54 factor family.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

93221:RO07 RS11880
gene id: 93221:RO07_RS11880
uniprot id: A0A378YZI6
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

93221:RO07 RS11250
gene id: 93221:RO07_RS11250
uniprot id: A0A378YZ03
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

93221:RO07 RS08540
gene id: 93221:RO07_RS08540
uniprot id: A0A378Z292
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS20940
gene id: 93221:RO07_RS20940
uniprot id: A0A378Z9B4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

93221:RO07 RS25065
gene id: 93221:RO07_RS25065
uniprot id: A0A378Z7G4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase delta chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.

93221:RO07 RS10875
gene id: 93221:RO07_RS10875
uniprot id: A0A378Z024
names: Similarity
messages: Belongs to the CmpA/NrtA family.

93221:RO07 RS21035
gene id: 93221:RO07_RS21035
uniprot id: A0A378Z9S1
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

93221:RO07 RS02950
gene id: 93221:RO07_RS02950
uniprot id: A0A378Z5G8
names: Subcellular Location Annotation
messages: Cell membrane
messages: Membrane

93221:RO07 RS07245
gene id: 93221:RO07_RS07245
uniprot id: A0A378Z2Q2
names: Similarity
messages: Belongs to the AHA1 family.

93221:RO07 RS00995
gene id: 93221:RO07_RS00995
uniprot id: A0A378Z4Q4
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

93221:RO07 RS24890
gene id: 93221:RO07_RS24890
uniprot id: A0A378Z5L1
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

93221:RO07 RS25015
gene id: 93221:RO07_RS25015
uniprot id: A0A378Z7H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

93221:RO07 RS11380
gene id: 93221:RO07_RS11380
uniprot id: A0A378YZS9
names: Function
names: Similarity
messages: Belongs to the alanine racemase family.
messages: Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.

93221:RO07 RS10905
gene id: 93221:RO07_RS10905
uniprot id: A0A378YZX8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS17255
gene id: 93221:RO07_RS17255
uniprot id: A0A378Z9Y0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93221:RO07 RS09475
gene id: 93221:RO07_RS09475
uniprot id: A0A378Z1N0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KdsA family.
messages: Cytoplasm

93221:RO07 RS16815
gene id: 93221:RO07_RS16815
uniprot id: A0A378ZA76
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15910
gene id: 93221:RO07_RS15910
uniprot id: A0A378ZBH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Nitrate/nitrite porter (TC 2.A.1.8) family.
messages: Membrane

93221:RO07 RS08985
gene id: 93221:RO07_RS08985
uniprot id: A0A378Z1Y0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS19630
gene id: 93221:RO07_RS19630
uniprot id: A0A378Z9E0
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA.
messages: Belongs to the helicase family. UvrD subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding. Interacts with RecA.
messages: The C-terminal domain has nuclease activity and interacts with RecD. It interacts with RecA, facilitating its loading onto ssDNA.
messages: The N-terminal DNA-binding domain is a ssDNA-dependent ATPase and has ATP-dependent 3'-5' helicase function. This domain interacts with RecC.

93221:RO07 RS13215
gene id: 93221:RO07_RS13215
uniprot id: A0A378ZDA1
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS09280
gene id: 93221:RO07_RS09280
uniprot id: A0A378Z1U9
names: Similarity
messages: Belongs to the nitroreductase family. HadB/RutE subfamily.

93221:RO07 RS13235
gene id: 93221:RO07_RS13235
uniprot id: A0A378ZD03
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS24530
gene id: 93221:RO07_RS24530
uniprot id: A0A378Z6P5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS16245
gene id: 93221:RO07_RS16245
uniprot id: A0A378ZAH1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

93221:RO07 RS20405
gene id: 93221:RO07_RS20405
uniprot id: A0A378Z858
names: Similarity
messages: Belongs to the Cob(I)alamin adenosyltransferase family.

93221:RO07 RS23350
gene id: 93221:RO07_RS23350
uniprot id: A0A378Z6H1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA-PH family.
messages: Cytoplasm

93221:RO07 RS22675
gene id: 93221:RO07_RS22675
uniprot id: A0A378Z6U5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22660
gene id: 93221:RO07_RS22660
uniprot id: A0A378Z8Q0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Cytoplasm
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

93221:RO07 RS05940
gene id: 93221:RO07_RS05940
uniprot id: A0A378Z3N1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93221:RO07 RS16150
gene id: 93221:RO07_RS16150
uniprot id: A0A378ZBJ2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23850
gene id: 93221:RO07_RS23850
uniprot id: A0A378Z660
names: Similarity
messages: Belongs to the ketopantoate reductase family.

93221:RO07 RS18245
gene id: 93221:RO07_RS18245
uniprot id: A0A378ZA52
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21415
gene id: 93221:RO07_RS21415
uniprot id: A0A378Z7J8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00610
gene id: 93221:RO07_RS00610
uniprot id: A0A378Z5P3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

93221:RO07 RS20420
gene id: 93221:RO07_RS20420
uniprot id: A0A378ZA38
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS11480
gene id: 93221:RO07_RS11480
uniprot id: A0A378YZQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRF family.
messages: Cytoplasm
messages: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.

93221:RO07 RS09025
gene id: 93221:RO07_RS09025
uniprot id: A0A378YZZ0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00500
gene id: 93221:RO07_RS00500
uniprot id: A0A378Z503
names: Domain
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CheB family.
messages: Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.
messages: Cytoplasm
messages: Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.
messages: Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.

93221:RO07 RS18585
gene id: 93221:RO07_RS18585
uniprot id: A0A378Z9X8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

93221:RO07 RS01470
gene id: 93221:RO07_RS01470
uniprot id: A0A378Z612
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS04360
gene id: 93221:RO07_RS04360
uniprot id: A0A378Z2Q3
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

93221:RO07 RS13815
gene id: 93221:RO07_RS13815
uniprot id: A0A378ZBT2
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS04945
gene id: 93221:RO07_RS04945
uniprot id: A0A378Z2C0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93221:RO07 RS06955
gene id: 93221:RO07_RS06955
uniprot id: A0A378Z1A9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

93221:RO07 RS13975
gene id: 93221:RO07_RS13975
uniprot id: A0A378ZBT3
names: Function
names: Similarity
messages: Belongs to the SELO family.
messages: Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).

93221:RO07 RS03975
gene id: 93221:RO07_RS03975
uniprot id: A0A378Z4D1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.
messages: Cytoplasm

93221:RO07 RS00725
gene id: 93221:RO07_RS00725
uniprot id: A0A378Z6F1
names: Function
names: Similarity
messages: Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.
messages: Belongs to the Fmt family.

93221:RO07 RS01930
gene id: 93221:RO07_RS01930
uniprot id: A0A378Z492
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

93221:RO07 RS22285
gene id: 93221:RO07_RS22285
uniprot id: A0A378Z8K8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.
messages: Binds 2 iron ions per subunit.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

93221:RO07 RS21480
gene id: 93221:RO07_RS21480
uniprot id: A0A378Z8A8
names: Similarity
messages: Belongs to the arylamine N-acetyltransferase family.

93221:RO07 RS03600
gene id: 93221:RO07_RS03600
uniprot id: A0A378Z4U5
names: Similarity
messages: Belongs to the NtaA/SnaA/DszA monooxygenase family.

93221:RO07 RS17135
gene id: 93221:RO07_RS17135
uniprot id: A0A378ZBQ7
names: Cofactor
names: Similarity
messages: Belongs to the monomeric-type IDH family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

93221:RO07 RS09670
gene id: 93221:RO07_RS09670
uniprot id: A0A378Z0L7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 4 family.
messages: Membrane

93221:RO07 RS21665
gene id: 93221:RO07_RS21665
uniprot id: A0A378Z875
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24550
gene id: 93221:RO07_RS24550
uniprot id: A0A378Z5S9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvH family.
messages: Binds 1 lipoyl cofactor covalently.
messages: The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93221:RO07 RS09385
gene id: 93221:RO07_RS09385
uniprot id: A0A378Z1E7
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 3 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS08200
gene id: 93221:RO07_RS08200
uniprot id: A0A378Z2N1
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS13630
gene id: 93221:RO07_RS13630
uniprot id: A0A378ZC01
names: Similarity
messages: Belongs to the glycosyl hydrolase 8 (cellulase D) family.

93221:RO07 RS15000
gene id: 93221:RO07_RS15000
uniprot id: A0A378ZB67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS17505
gene id: 93221:RO07_RS17505
uniprot id: A0A378Z9S9
names: Caution
names: Function
names: Similarity
messages: Belongs to the globin family. Two-domain flavohemoproteins subfamily.
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS02000
gene id: 93221:RO07_RS02000
uniprot id: A0A378Z525
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.
messages: Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.
messages: Homodimer.

93221:RO07 RS19475
gene id: 93221:RO07_RS19475
uniprot id: A0A378Z9H0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS06110
gene id: 93221:RO07_RS06110
uniprot id: A0A378Z1S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0391 family.
messages: Cell membrane

93221:RO07 RS23840
gene id: 93221:RO07_RS23840
uniprot id: A0A378Z7D8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00125
gene id: 93221:RO07_RS00125
uniprot id: A0A378Z776
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

93221:RO07 RS25400
gene id: 93221:RO07_RS25400
uniprot id: A0A378Z609
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

93221:RO07 RS22805
gene id: 93221:RO07_RS22805
uniprot id: A0A378Z8A6
names: Caution
names: Function
names: Similarity
messages: Belongs to the UbiX/PAD1 family.
messages: Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS21345
gene id: 93221:RO07_RS21345
uniprot id: A0A378Z9L2
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

93221:RO07 RS23590
gene id: 93221:RO07_RS23590
uniprot id: A0A378Z7J4
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the MsrP family.
messages: Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.
messages: Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).
messages: Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.
messages: Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.

93221:RO07 RS16130
gene id: 93221:RO07_RS16130
uniprot id: A0A378ZCL8
names: Similarity
messages: Belongs to the Gfa family.

93221:RO07 RS19180
gene id: 93221:RO07_RS19180
uniprot id: A0A378Z9X7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS11800
gene id: 93221:RO07_RS11800
uniprot id: A0A378YYP7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00830
gene id: 93221:RO07_RS00830
uniprot id: A0A378Z6N7
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Heterotrimer of A, B and C subunits.

93221:RO07 RS16335
gene id: 93221:RO07_RS16335
uniprot id: A0A378ZAE9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
messages: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.
messages: Cytoplasm
messages: Monomer.
messages: The C-terminal coiled-coil domain is crucial for aminoacylation activity.
messages: ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.

93221:RO07 RS21900
gene id: 93221:RO07_RS21900
uniprot id: A0A378Z8F1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS22700
gene id: 93221:RO07_RS22700
uniprot id: A0A378Z8U7
names: Function
names: Similarity
messages: ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.

93221:RO07 RS08785
gene id: 93221:RO07_RS08785
uniprot id: A0A378Z2B6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.
messages: Binds 1 FMN per subunit.
messages: Catalyzes the conversion of dihydroorotate to orotate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS09830
gene id: 93221:RO07_RS09830
uniprot id: A0A378YZI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS19505
gene id: 93221:RO07_RS19505
uniprot id: A0A378Z8P8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17610
gene id: 93221:RO07_RS17610
uniprot id: A0A378Z9R4
names: Similarity
messages: Belongs to the DapA family.

93221:RO07 RS14630
gene id: 93221:RO07_RS14630
uniprot id: A0A378ZC74
names: Similarity
messages: Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.

93221:RO07 RS09820
gene id: 93221:RO07_RS09820
uniprot id: A0A378YZS7
names: Cofactor
names: Subunit
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD. The complex can form homotrimers.
messages: The heme is bound between the two transmembrane subunits.

93221:RO07 RS01580
gene id: 93221:RO07_RS01580
uniprot id: A0A378Z692
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

93221:RO07 RS24755
gene id: 93221:RO07_RS24755
uniprot id: A0A378Z7M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

93221:RO07 RS11490
gene id: 93221:RO07_RS11490
uniprot id: A0A378YYN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

93221:RO07 RS10165
gene id: 93221:RO07_RS10165
uniprot id: A0A378Z0F3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YbaB/EbfC family.
messages: Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
messages: Homodimer.
messages: nucleoid

93221:RO07 RS07675
gene id: 93221:RO07_RS07675
uniprot id: A0A378Z0T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

93221:RO07 RS06550
gene id: 93221:RO07_RS06550
uniprot id: A0A378Z3F2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M17 family.
messages: Binds 2 manganese ions per subunit.
messages: Cytoplasm
messages: Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.

93221:RO07 RS22240
gene id: 93221:RO07_RS22240
uniprot id: A0A378Z8X5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type-II 3-dehydroquinase family.
messages: Catalyzes a trans-dehydration via an enolate intermediate.
messages: Homododecamer.

93221:RO07 RS03035
gene id: 93221:RO07_RS03035
uniprot id: A0A378Z3H4
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS24145
gene id: 93221:RO07_RS24145
uniprot id: A0A378Z608
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. RhlE subfamily.
messages: Cytoplasm
messages: DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA.

93221:RO07 RS22600
gene id: 93221:RO07_RS22600
uniprot id: A0A378Z6Z9
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS04850
gene id: 93221:RO07_RS04850
uniprot id: A0A378Z2J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliN/MopA/SpaO family.
messages: Membrane

93221:RO07 RS01490
gene id: 93221:RO07_RS01490
uniprot id: A0A378Z4F6
names: Similarity
messages: Belongs to the GSP E family.

93221:RO07 RS25085
gene id: 93221:RO07_RS25085
uniprot id: A0A378Z6R0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS11160
gene id: 93221:RO07_RS11160
uniprot id: A0A378YZT4
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.
messages: Binds to the 23S rRNA.

93221:RO07 RS21015
gene id: 93221:RO07_RS21015
uniprot id: A0A378Z7R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RseB family.
messages: Periplasm

93221:RO07 RS11240
gene id: 93221:RO07_RS11240
uniprot id: A0A378YYT6
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

93221:RO07 RS22255
gene id: 93221:RO07_RS22255
uniprot id: A0A378Z728
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. PrmA family.
messages: Cytoplasm
messages: Methylates ribosomal protein L11.

93221:RO07 RS18280
gene id: 93221:RO07_RS18280
uniprot id: A0A378Z9D7
names: Similarity
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.

93221:RO07 RS24940
gene id: 93221:RO07_RS24940
uniprot id: A0A378Z5J2
names: Function
names: Similarity
messages: Belongs to the GTP-binding SRP family.
messages: Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.

93221:RO07 RS09215
gene id: 93221:RO07_RS09215
uniprot id: A0A378Z0V5
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS00580
gene id: 93221:RO07_RS00580
uniprot id: A0A378Z6I5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24880
gene id: 93221:RO07_RS24880
uniprot id: A0A378Z5K2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS11585
gene id: 93221:RO07_RS11585
uniprot id: A0A378Z093
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

93221:RO07 RS02810
gene id: 93221:RO07_RS02810
uniprot id: A0A378Z4K6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS18720
gene id: 93221:RO07_RS18720
uniprot id: A0A378Z928
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS11395
gene id: 93221:RO07_RS11395
uniprot id: A0A378YYP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsA sub-subfamily.
messages: Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane
messages: Membrane

93221:RO07 RS06155
gene id: 93221:RO07_RS06155
uniprot id: A0A378Z394
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22195
gene id: 93221:RO07_RS22195
uniprot id: A0A378Z7Y9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 51 family.
messages: Cell inner membrane
messages: Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.

93221:RO07 RS16360
gene id: 93221:RO07_RS16360
uniprot id: A0A378ZCI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
messages: Homotetramer.

93221:RO07 RS09450
gene id: 93221:RO07_RS09450
uniprot id: A0A378YZQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. Lipoprotein translocase (TC 3.A.1.125) family.
messages: Cell inner membrane
messages: Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner.
messages: The complex is composed of two ATP-binding proteins (LolD) and two transmembrane proteins (LolC and LolE).

93221:RO07 RS23290
gene id: 93221:RO07_RS23290
uniprot id: A0A378Z7P9
names: Similarity
messages: Belongs to the GST superfamily. HSP26 family.

93221:RO07 RS16090
gene id: 93221:RO07_RS16090
uniprot id: A0A378ZC22
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS18730
gene id: 93221:RO07_RS18730
uniprot id: A0A378Z940
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the chaperonin (HSP60) family.
messages: Cytoplasm
messages: Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.

93221:RO07 RS11465
gene id: 93221:RO07_RS11465
uniprot id: A0A378Z0T9
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

93221:RO07 RS01065
gene id: 93221:RO07_RS01065
uniprot id: A0A378Z4R2
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS23415
gene id: 93221:RO07_RS23415
uniprot id: A0A378Z6H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS20710
gene id: 93221:RO07_RS20710
uniprot id: A0A378Z7Z4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS02310
gene id: 93221:RO07_RS02310
uniprot id: A0A378Z5D1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
messages: Cytoplasm
messages: In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.

93221:RO07 RS23655
gene id: 93221:RO07_RS23655
uniprot id: A0A378Z6B1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

93221:RO07 RS17895
gene id: 93221:RO07_RS17895
uniprot id: A0A378Z9I9
names: Similarity
messages: Belongs to the OsmC/Ohr family.

93221:RO07 RS11215
gene id: 93221:RO07_RS11215
uniprot id: A0A378Z0Z0
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

93221:RO07 RS01445
gene id: 93221:RO07_RS01445
uniprot id: A0A378Z4G8
names: Subcellular Location Annotation
messages: Mitochondrion

93221:RO07 RS03630
gene id: 93221:RO07_RS03630
uniprot id: A0A378Z371
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20135
gene id: 93221:RO07_RS20135
uniprot id: A0A378Z935
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS20 family.
messages: Binds directly to 16S ribosomal RNA.

93221:RO07 RS18405
gene id: 93221:RO07_RS18405
uniprot id: A0A378ZB32
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

93221:RO07 RS21865
gene id: 93221:RO07_RS21865
uniprot id: A0A378Z7B4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01830
gene id: 93221:RO07_RS01830
uniprot id: A0A378Z4B0
names: Subcellular Location Annotation
messages: Periplasm

93221:RO07 RS11820
gene id: 93221:RO07_RS11820
uniprot id: A0A378Z0C3
names: Similarity
messages: Belongs to the BMP lipoprotein family.

93221:RO07 RS22625
gene id: 93221:RO07_RS22625
uniprot id: A0A378Z6W0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.

93221:RO07 RS19175
gene id: 93221:RO07_RS19175
uniprot id: A0A378Z9M9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS02170
gene id: 93221:RO07_RS02170
uniprot id: A0A378Z428
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS25190
gene id: 93221:RO07_RS25190
uniprot id: A0A378Z5E8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10780
gene id: 93221:RO07_RS10780
uniprot id: A0A378Z0P7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the dTDP-4-dehydrorhamnose reductase family.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.

93221:RO07 RS17025
gene id: 93221:RO07_RS17025
uniprot id: A0A378ZBK3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS07650
gene id: 93221:RO07_RS07650
uniprot id: A0A378Z0R9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

93221:RO07 RS06970
gene id: 93221:RO07_RS06970
uniprot id: A0A378Z269
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HMBS family.
messages: Binds 1 dipyrromethane group covalently.
messages: Monomer.
messages: Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
messages: The porphobilinogen subunits are added to the dipyrromethane group.

93221:RO07 RS09030
gene id: 93221:RO07_RS09030
uniprot id: A0A378Z257
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17995
gene id: 93221:RO07_RS17995
uniprot id: A0A378Z9G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-2 integral membrane protein family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS18360
gene id: 93221:RO07_RS18360
uniprot id: A0A378ZA29
names: Similarity
messages: Belongs to the CFA/CMAS family.

93221:RO07 RS05985
gene id: 93221:RO07_RS05985
uniprot id: A0A378Z3Z1
names: Similarity
messages: Belongs to the type III secretion exporter family.

93221:RO07 RS21670
gene id: 93221:RO07_RS21670
uniprot id: A0A378Z7I0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17105
gene id: 93221:RO07_RS17105
uniprot id: A0A378ZA11
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase H family.
messages: Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.
messages: Cytoplasm
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Monomer.

93221:RO07 RS02390
gene id: 93221:RO07_RS02390
uniprot id: A0A378Z610
names: Similarity
messages: Belongs to the P(II) protein family.

93221:RO07 RS12010
gene id: 93221:RO07_RS12010
uniprot id: A0A378Z0D7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. DIT1 subfamily.
messages: Membrane

93221:RO07 RS19705
gene id: 93221:RO07_RS19705
uniprot id: A0A378Z9A1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

93221:RO07 RS16365
gene id: 93221:RO07_RS16365
uniprot id: A0A378ZBX5
names: Similarity
messages: Belongs to the 4-oxalocrotonate tautomerase family.

93221:RO07 RS23335
gene id: 93221:RO07_RS23335
uniprot id: A0A378Z7D1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatA/E family.
messages: Cell membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93221:RO07 RS18390
gene id: 93221:RO07_RS18390
uniprot id: A0A378Z9B7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.
messages: Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide.

93221:RO07 RS02890
gene id: 93221:RO07_RS02890
uniprot id: A0A378Z3K5
names: Similarity
messages: Belongs to the GcvT family.

93221:RO07 RS16805
gene id: 93221:RO07_RS16805
uniprot id: A0A378ZA73
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS11460
gene id: 93221:RO07_RS11460
uniprot id: A0A378YYM0
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

93221:RO07 RS07480
gene id: 93221:RO07_RS07480
uniprot id: A0A378Z2T6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93221:RO07 RS13685
gene id: 93221:RO07_RS13685
uniprot id: A0A378ZDZ2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the succinylarginine dihydrolase family.
messages: Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2).
messages: Homodimer.

93221:RO07 RS23935
gene id: 93221:RO07_RS23935
uniprot id: A0A378Z7W8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

93221:RO07 RS23535
gene id: 93221:RO07_RS23535
uniprot id: A0A378Z7K4
names: Similarity
messages: Belongs to the dGTPase family. Type 2 subfamily.

93221:RO07 RS09885
gene id: 93221:RO07_RS09885
uniprot id: A0A378Z1P2
names: Similarity
messages: Belongs to the TrpF family.

93221:RO07 RS24095
gene id: 93221:RO07_RS24095
uniprot id: A0A378Z620
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CrcB (TC 9.B.71) family.
messages: Cell membrane
messages: Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
messages: Membrane

93221:RO07 RS10775
gene id: 93221:RO07_RS10775
uniprot id: A0A378Z040
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.

93221:RO07 RS03580
gene id: 93221:RO07_RS03580
uniprot id: A0A378Z377
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OpgD/OpgG family.
messages: Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs).
messages: Periplasm

93221:RO07 RS08960
gene id: 93221:RO07_RS08960
uniprot id: A0A378Z014
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

93221:RO07 RS19535
gene id: 93221:RO07_RS19535
uniprot id: A0A378Z8M4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

93221:RO07 RS09100
gene id: 93221:RO07_RS09100
uniprot id: A0A378YZY8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DNA polymerase type-Y family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.

93221:RO07 RS12460
gene id: 93221:RO07_RS12460
uniprot id: A0A378YZ26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LRR-containing bacterial E3 ligase family.
messages: Host cytoplasm
messages: Secreted

93221:RO07 RS23475
gene id: 93221:RO07_RS23475
uniprot id: A0A378Z874
names: Similarity
messages: Belongs to the DAMOX/DASOX family.

93221:RO07 RS22335
gene id: 93221:RO07_RS22335
uniprot id: A0A378Z8J7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.
messages: Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.
messages: Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS01175
gene id: 93221:RO07_RS01175
uniprot id: A0A378Z671
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AB hydrolase superfamily. MetX family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.

93221:RO07 RS03815
gene id: 93221:RO07_RS03815
uniprot id: A0A378Z311
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS07645
gene id: 93221:RO07_RS07645
uniprot id: A0A378Z1S0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS12020
gene id: 93221:RO07_RS12020
uniprot id: A0A378Z025
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase epsilon chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

93221:RO07 RS17780
gene id: 93221:RO07_RS17780
uniprot id: A0A378ZB61
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the selenophosphate synthase 1 family. Class I subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Homodimer.
messages: Synthesizes selenophosphate from selenide and ATP.

93221:RO07 RS09990
gene id: 93221:RO07_RS09990
uniprot id: A0A378Z1C7
names: Function
names: Subunit
messages: Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
messages: Homodimer. Part of the PDH complex, consisting of multiple copies of pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

93221:RO07 RS22280
gene id: 93221:RO07_RS22280
uniprot id: A0A378Z932
names: Function
names: Similarity
messages: Belongs to the histone H1/H5 family. HCT subfamily.
messages: Might have a role in establishing the nucleoid structure of elementary bodies.

93221:RO07 RS03970
gene id: 93221:RO07_RS03970
uniprot id: A0A378Z3W0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS20765
gene id: 93221:RO07_RS20765
uniprot id: A0A378Z8N9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15355
gene id: 93221:RO07_RS15355
uniprot id: A0A378ZBS7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the acetolactate synthase small subunit family.
messages: Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.
messages: Dimer of large and small chains.

93221:RO07 RS11035
gene id: 93221:RO07_RS11035
uniprot id: A0A378YZZ5
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
messages: Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.

93221:RO07 RS05130
gene id: 93221:RO07_RS05130
uniprot id: A0A378Z2E8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

93221:RO07 RS23630
gene id: 93221:RO07_RS23630
uniprot id: A0A378Z839
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL17 family.
messages: Part of the 50S ribosomal subunit. Contacts protein L32.

93221:RO07 RS07750
gene id: 93221:RO07_RS07750
uniprot id: A0A378Z2M9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family. DXPS subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
messages: Homodimer.

93221:RO07 RS01675
gene id: 93221:RO07_RS01675
uniprot id: A0A378Z6F0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the argininosuccinate synthase family. Type 2 subfamily.
messages: Cytoplasm
messages: Homotetramer.

93221:RO07 RS08175
gene id: 93221:RO07_RS08175
uniprot id: A0A378Z247
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

93221:RO07 RS19455
gene id: 93221:RO07_RS19455
uniprot id: A0A378Z8Q7
names: Function
names: Similarity
messages: Belongs to the NadD family.
messages: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).

93221:RO07 RS15220
gene id: 93221:RO07_RS15220
uniprot id: A0A378ZCI1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS14555
gene id: 93221:RO07_RS14555
uniprot id: A0A378ZC59
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22635
gene id: 93221:RO07_RS22635
uniprot id: A0A378Z6X6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate synthase component I family.
messages: Heterotetramer consisting of two non-identical subunits: a beta subunit (TrpG) and a large alpha subunit (TrpE).
messages: Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia.

93221:RO07 RS23315
gene id: 93221:RO07_RS23315
uniprot id: A0A378Z6J2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

93221:RO07 RS23395
gene id: 93221:RO07_RS23395
uniprot id: A0A378Z6E6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the histidinol dehydrogenase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.

93221:RO07 RS15535
gene id: 93221:RO07_RS15535
uniprot id: A0A378ZAW7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase subunit omega family.
messages: Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93221:RO07 RS05650
gene id: 93221:RO07_RS05650
uniprot id: A0A378Z310
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00010
gene id: 93221:RO07_RS00010
uniprot id: A0A378Z7A0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the beta sliding clamp family.
messages: Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.
messages: Cytoplasm
messages: Forms a ring-shaped head-to-tail homodimer around DNA.

93221:RO07 RS21600
gene id: 93221:RO07_RS21600
uniprot id: A0A378Z7F7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS23705
gene id: 93221:RO07_RS23705
uniprot id: A0A378Z699
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.
messages: This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.

93221:RO07 RS21100
gene id: 93221:RO07_RS21100
uniprot id: A0A378Z8K3
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNase E/G family. RNase E subfamily.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per homotetramer.
messages: Cell inner membrane
messages: Cytoplasm
messages: Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs.
messages: Homotetramer formed by a dimer of dimers.

93221:RO07 RS01215
gene id: 93221:RO07_RS01215
uniprot id: A0A378Z4N4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.
messages: Cytoplasm
messages: May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.

93221:RO07 RS13230
gene id: 93221:RO07_RS13230
uniprot id: A0A378ZC68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

93221:RO07 RS16120
gene id: 93221:RO07_RS16120
uniprot id: A0A378ZBD0
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

93221:RO07 RS20365
gene id: 93221:RO07_RS20365
uniprot id: A0A378Z873
names: Function
names: Similarity
messages: Belongs to the HrcA family.
messages: Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.

93221:RO07 RS06745
gene id: 93221:RO07_RS06745
uniprot id: A0A378Z381
names: Similarity
messages: Belongs to the ferredoxin--NADP reductase type 1 family.

93221:RO07 RS23890
gene id: 93221:RO07_RS23890
uniprot id: A0A378Z7C6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 2 Zn(2+) ions per subunit.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.

93221:RO07 RS24075
gene id: 93221:RO07_RS24075
uniprot id: A0A378Z7V0
names: Similarity
messages: Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.

93221:RO07 RS07610
gene id: 93221:RO07_RS07610
uniprot id: A0A378Z2Q6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS04245
gene id: 93221:RO07_RS04245
uniprot id: A0A378Z2W0
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS17435
gene id: 93221:RO07_RS17435
uniprot id: A0A378ZBD5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

93221:RO07 RS09675
gene id: 93221:RO07_RS09675
uniprot id: A0A378YZK6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 2 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS04420
gene id: 93221:RO07_RS04420
uniprot id: A0A378Z4E0
names: Similarity
names: Subunit
messages: Belongs to the Nudix hydrolase family. NudJ subfamily.
messages: Monomer.

93221:RO07 RS19415
gene id: 93221:RO07_RS19415
uniprot id: A0A378ZA74
names: Function
names: Similarity
messages: Belongs to the methylglyoxal synthase family.
messages: Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.

93221:RO07 RS03700
gene id: 93221:RO07_RS03700
uniprot id: A0A378Z502
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS24950
gene id: 93221:RO07_RS24950
uniprot id: A0A378Z695
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

93221:RO07 RS23770
gene id: 93221:RO07_RS23770
uniprot id: A0A378Z877
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS10 family.
messages: Involved in the binding of tRNA to the ribosomes.
messages: Part of the 30S ribosomal subunit.

93221:RO07 RS06945
gene id: 93221:RO07_RS06945
uniprot id: A0A378Z2B3
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-I family.

93221:RO07 RS19440
gene id: 93221:RO07_RS19440
uniprot id: A0A378Z8P1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TACO1 family.
messages: Cytoplasm

93221:RO07 RS21070
gene id: 93221:RO07_RS21070
uniprot id: A0A378Z7S2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YceF subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes 7-methyl-GTP (m(7)GTP). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

93221:RO07 RS17555
gene id: 93221:RO07_RS17555
uniprot id: A0A378Z9S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 3-HAO family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Homodimer.

93221:RO07 RS11385
gene id: 93221:RO07_RS11385
uniprot id: A0A378Z0D3
names: Domain
names: Function
names: Similarity
messages: Belongs to the RecA family. RadA subfamily.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
messages: Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.
messages: The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.

93221:RO07 RS18910
gene id: 93221:RO07_RS18910
uniprot id: A0A378Z8Y9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS01665
gene id: 93221:RO07_RS01665
uniprot id: A0A378Z547
names: Similarity
messages: Belongs to the AB hydrolase superfamily. Lipase family.

93221:RO07 RS01020
gene id: 93221:RO07_RS01020
uniprot id: A0A378Z6Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis.
messages: Belongs to the ClpX chaperone family. HslU subfamily.
messages: Cytoplasm

93221:RO07 RS09540
gene id: 93221:RO07_RS09540
uniprot id: A0A378Z1B6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

93221:RO07 RS24540
gene id: 93221:RO07_RS24540
uniprot id: A0A378Z5S6
names: Similarity
messages: Belongs to the iron-sulfur dependent L-serine dehydratase family.

93221:RO07 RS11330
gene id: 93221:RO07_RS11330
uniprot id: A0A378YZT9
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.
messages: Catalyzes the hydrolytic dehalogenation of small (S)-2-haloalkanoic acids to yield the corresponding (R)-2-hydroxyalkanoic acids.

93221:RO07 RS16885
gene id: 93221:RO07_RS16885
uniprot id: A0A378ZAX4
names: Function
names: PTM
names: Similarity
messages: An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.
messages: Belongs to the polyphosphate kinase 1 (PPK1) family.
messages: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).

93221:RO07 RS12275
gene id: 93221:RO07_RS12275
uniprot id: A0A378YY77
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

93221:RO07 RS24885
gene id: 93221:RO07_RS24885
uniprot id: A0A378Z5K1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS19910
gene id: 93221:RO07_RS19910
uniprot id: A0A378Z8G0
names: Function
names: Similarity
messages: Belongs to the NadC/ModD family.
messages: Involved in the catabolism of quinolinic acid (QA).

93221:RO07 RS04860
gene id: 93221:RO07_RS04860
uniprot id: A0A378Z2E0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

93221:RO07 RS02770
gene id: 93221:RO07_RS02770
uniprot id: A0A378Z3P2
names: Similarity
names: Subunit
messages: Belongs to the KdsC family.
messages: Homotetramer.

93221:RO07 RS23670
gene id: 93221:RO07_RS23670
uniprot id: A0A378Z899
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL15 family.
messages: Binds to the 23S rRNA.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS08840
gene id: 93221:RO07_RS08840
uniprot id: A0A378Z210
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS08995
gene id: 93221:RO07_RS08995
uniprot id: A0A378Z151
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

93221:RO07 RS12235
gene id: 93221:RO07_RS12235
uniprot id: A0A378YZ75
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

93221:RO07 RS06980
gene id: 93221:RO07_RS06980
uniprot id: A0A378Z337
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Involved in a late step of protoheme IX synthesis.
messages: Membrane

93221:RO07 RS24790
gene id: 93221:RO07_RS24790
uniprot id: A0A378Z5N1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

93221:RO07 RS11155
gene id: 93221:RO07_RS11155
uniprot id: A0A378YZ23
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bS18 family.
messages: Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.

93221:RO07 RS03985
gene id: 93221:RO07_RS03985
uniprot id: A0A378Z2X4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S33 family.
messages: Cytoplasm

93221:RO07 RS20290
gene id: 93221:RO07_RS20290
uniprot id: A0A378Z9B2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanB family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.
messages: Cytoplasm
messages: Homodecamer; pentamer of dimers.

93221:RO07 RS24520
gene id: 93221:RO07_RS24520
uniprot id: A0A378Z7B8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Catalyzes the sodium-dependent uptake of extracellular L-proline.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS16585
gene id: 93221:RO07_RS16585
uniprot id: A0A378ZBB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OmpP1/FadL family.
messages: Cell outer membrane
messages: Membrane

93221:RO07 RS19565
gene id: 93221:RO07_RS19565
uniprot id: A0A378ZA39
names: Similarity
messages: Belongs to the DEAD box helicase family.

93221:RO07 RS04550
gene id: 93221:RO07_RS04550
uniprot id: A0A378Z2Q7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS22015
gene id: 93221:RO07_RS22015
uniprot id: A0A378Z782
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
messages: Cytoplasm
messages: Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.

93221:RO07 RS15560
gene id: 93221:RO07_RS15560
uniprot id: A0A378ZBX4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.
messages: Cytoplasm
messages: Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.

93221:RO07 RS19850
gene id: 93221:RO07_RS19850
uniprot id: A0A378Z8H5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20350
gene id: 93221:RO07_RS20350
uniprot id: A0A378Z852
names: Similarity
messages: Belongs to the HSP15 family.

93221:RO07 RS08460
gene id: 93221:RO07_RS08460
uniprot id: A0A378Z0B6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

93221:RO07 RS06790
gene id: 93221:RO07_RS06790
uniprot id: A0A378Z1B2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

93221:RO07 RS22265
gene id: 93221:RO07_RS22265
uniprot id: A0A378Z736
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the peroxiredoxin family. Tpx subfamily.
messages: Homodimer.
messages: The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

93221:RO07 RS17185
gene id: 93221:RO07_RS17185
uniprot id: A0A378ZBP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. YhhS family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS06925
gene id: 93221:RO07_RS06925
uniprot id: A0A378Z278
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.

93221:RO07 RS17430
gene id: 93221:RO07_RS17430
uniprot id: A0A378ZBY9
names: Similarity
messages: Belongs to the peptidase M1 family.

93221:RO07 RS05380
gene id: 93221:RO07_RS05380
uniprot id: A0A378Z3N4
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS11485
gene id: 93221:RO07_RS11485
uniprot id: A0A378Z0B3
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the UPP synthase family.
messages: Binds 2 magnesium ions per subunit.
messages: Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
messages: Homodimer.

93221:RO07 RS06505
gene id: 93221:RO07_RS06505
uniprot id: A0A378Z2J6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04940
gene id: 93221:RO07_RS04940
uniprot id: A0A378Z2E7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.

93221:RO07 RS18540
gene id: 93221:RO07_RS18540
uniprot id: A0A378Z983
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane.

93221:RO07 RS21105
gene id: 93221:RO07_RS21105
uniprot id: A0A378Z8U8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. MoaA family.
messages: Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.
messages: Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
messages: Monomer and homodimer.

93221:RO07 RS16490
gene id: 93221:RO07_RS16490
uniprot id: A0A378ZBC7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

93221:RO07 RS07880
gene id: 93221:RO07_RS07880
uniprot id: A0A378Z0N4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS09965
gene id: 93221:RO07_RS09965
uniprot id: A0A378YZF8
names: Function
names: Similarity
messages: Belongs to the SsuD family.
messages: Catalyzes the desulfonation of aliphatic sulfonates.

93221:RO07 RS02480
gene id: 93221:RO07_RS02480
uniprot id: A0A378Z4P0
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily.
messages: Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.

93221:RO07 RS19785
gene id: 93221:RO07_RS19785
uniprot id: A0A378Z9K1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.
messages: Homotetramer.
messages: Uses inorganic polyphosphate (polyP) as a donor to convert GDP to GTP or ADP to ATP.

93221:RO07 RS18325
gene id: 93221:RO07_RS18325
uniprot id: A0A378ZA35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

93221:RO07 RS12690
gene id: 93221:RO07_RS12690
uniprot id: A0A379LPA3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21695
gene id: 93221:RO07_RS21695
uniprot id: A0A378Z8H9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YqgF HJR family.
messages: Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.
messages: Cytoplasm

93221:RO07 RS11145
gene id: 93221:RO07_RS11145
uniprot id: A0A378YYV0
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.
messages: Binds together with S18 to 16S ribosomal RNA.

93221:RO07 RS12775
gene id: 93221:RO07_RS12775
uniprot id: A0A379LP69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10700
gene id: 93221:RO07_RS10700
uniprot id: A0A378Z0Y8
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

93221:RO07 RS09355
gene id: 93221:RO07_RS09355
uniprot id: A0A378Z0S5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HscB family.
messages: Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA.
messages: Interacts with HscA and stimulates its ATPase activity.

93221:RO07 RS00435
gene id: 93221:RO07_RS00435
uniprot id: A0A378Z5X9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05935
gene id: 93221:RO07_RS05935
uniprot id: A0A378Z3Z9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS11030
gene id: 93221:RO07_RS11030
uniprot id: A0A378Z0X4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RbfA family.
messages: Cytoplasm
messages: Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.
messages: One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.

93221:RO07 RS23400
gene id: 93221:RO07_RS23400
uniprot id: A0A378Z6F8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Lacks the C-terminal regulatory region which is replaced by HisZ.

93221:RO07 RS09285
gene id: 93221:RO07_RS09285
uniprot id: A0A378Z0Z1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.

93221:RO07 RS07440
gene id: 93221:RO07_RS07440
uniprot id: A0A378Z212
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15240
gene id: 93221:RO07_RS15240
uniprot id: A0A378ZB01
names: Similarity
messages: Belongs to the WrbA family.

93221:RO07 RS11500
gene id: 93221:RO07_RS11500
uniprot id: A0A378YYU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M50B family.
messages: Membrane

93221:RO07 RS21010
gene id: 93221:RO07_RS21010
uniprot id: A0A378Z7S8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

93221:RO07 RS09925
gene id: 93221:RO07_RS09925
uniprot id: A0A378Z0H8
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS16380
gene id: 93221:RO07_RS16380
uniprot id: A0A378ZBE6
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
messages: Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.
messages: Cytoplasm

93221:RO07 RS01765
gene id: 93221:RO07_RS01765
uniprot id: A0A378Z4B4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS13415
gene id: 93221:RO07_RS13415
uniprot id: A0A378ZC30
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13820
gene id: 93221:RO07_RS13820
uniprot id: A0A378ZCN4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10150
gene id: 93221:RO07_RS10150
uniprot id: A0A378Z195
names: Similarity
messages: Belongs to the thioredoxin family.

93221:RO07 RS01210
gene id: 93221:RO07_RS01210
uniprot id: A0A378Z5D3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS14545
gene id: 93221:RO07_RS14545
uniprot id: A0A378ZCW9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the helicase family. RecG subfamily.
messages: In the N-terminal section; belongs to the UvrB family.

93221:RO07 RS18735
gene id: 93221:RO07_RS18735
uniprot id: A0A378Z9U3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GroES chaperonin family.
messages: Cytoplasm
messages: Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.
messages: Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.

93221:RO07 RS01050
gene id: 93221:RO07_RS01050
uniprot id: A0A378Z4P6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetylglutamate kinase family. ArgB subfamily.
messages: Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.
messages: Cytoplasm

93221:RO07 RS01480
gene id: 93221:RO07_RS01480
uniprot id: A0A378Z5C2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05410
gene id: 93221:RO07_RS05410
uniprot id: A0A378Z231
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS07365
gene id: 93221:RO07_RS07365
uniprot id: A0A378Z1Z0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS03505
gene id: 93221:RO07_RS03505
uniprot id: A0A378Z545
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS13690
gene id: 93221:RO07_RS13690
uniprot id: A0A378ZDF6
names: Function
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family. AstD subfamily.
messages: Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate.

93221:RO07 RS13770
gene id: 93221:RO07_RS13770
uniprot id: A0A378ZBX0
names: Similarity
messages: Belongs to the Dps family.

93221:RO07 RS12435
gene id: 93221:RO07_RS12435
uniprot id: A0A378YZZ2
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS21215
gene id: 93221:RO07_RS21215
uniprot id: A0A378Z8S2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21000
gene id: 93221:RO07_RS21000
uniprot id: A0A378Z8M5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Cell membrane
messages: Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.

93221:RO07 RS08135
gene id: 93221:RO07_RS08135
uniprot id: A0A378Z0H7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS11965
gene id: 93221:RO07_RS11965
uniprot id: A0A378Z0E7
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93221:RO07 RS09360
gene id: 93221:RO07_RS09360
uniprot id: A0A378YZR7
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.

93221:RO07 RS03610
gene id: 93221:RO07_RS03610
uniprot id: A0A378Z431
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15540
gene id: 93221:RO07_RS15540
uniprot id: A0A378ZCX6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the guanylate kinase family.
messages: Cytoplasm
messages: Essential for recycling GMP and indirectly, cGMP.

93221:RO07 RS07775
gene id: 93221:RO07_RS07775
uniprot id: A0A378Z0R0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04210
gene id: 93221:RO07_RS04210
uniprot id: A0A378Z4Z8
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

93221:RO07 RS07120
gene id: 93221:RO07_RS07120
uniprot id: A0A378Z3C5
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
messages: Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
messages: Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
messages: Cytoplasm
messages: Homodimer. The tRNA molecule binds across the dimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS24430
gene id: 93221:RO07_RS24430
uniprot id: A0A378Z6R5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS07985
gene id: 93221:RO07_RS07985
uniprot id: A0A378Z0K9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23045
gene id: 93221:RO07_RS23045
uniprot id: A0A378Z6N1
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.

93221:RO07 RS08105
gene id: 93221:RO07_RS08105
uniprot id: A0A378Z2Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EamA transporter family.
messages: Membrane

93221:RO07 RS14115
gene id: 93221:RO07_RS14115
uniprot id: A0A378ZCR2
names: Function
names: Similarity
names: Subunit
messages: ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.
messages: Belongs to the ParA family. MinD subfamily.
messages: Interacts with MinC and FtsZ.

93221:RO07 RS11115
gene id: 93221:RO07_RS11115
uniprot id: A0A378YYU2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS03070
gene id: 93221:RO07_RS03070
uniprot id: A0A378Z3H3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS01550
gene id: 93221:RO07_RS01550
uniprot id: A0A378Z4E8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS16040
gene id: 93221:RO07_RS16040
uniprot id: A0A378ZC32
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01795
gene id: 93221:RO07_RS01795
uniprot id: A0A378Z658
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01275
gene id: 93221:RO07_RS01275
uniprot id: A0A378Z651
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SIMIBI class G3E GTPase family. UreG subfamily.
messages: Cytoplasm
messages: Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
messages: Homodimer. UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

93221:RO07 RS04150
gene id: 93221:RO07_RS04150
uniprot id: A0A378Z3Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93221:RO07 RS05080
gene id: 93221:RO07_RS05080
uniprot id: A0A378Z2F3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

93221:RO07 RS25290
gene id: 93221:RO07_RS25290
uniprot id: A0A378Z5C8
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

93221:RO07 RS23915
gene id: 93221:RO07_RS23915
uniprot id: A0A378Z655
names: Function
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL11 family.
messages: Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
messages: One or more lysine residues are methylated.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

93221:RO07 RS22450
gene id: 93221:RO07_RS22450
uniprot id: A0A378Z853
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.
messages: Cell membrane
messages: Self-interacts. Interacts with FtsZ.

93221:RO07 RS22500
gene id: 93221:RO07_RS22500
uniprot id: A0A378Z844
names: Function
names: Similarity
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.

93221:RO07 RS11695
gene id: 93221:RO07_RS11695
uniprot id: A0A378YYI8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS01115
gene id: 93221:RO07_RS01115
uniprot id: A0A378Z4Q5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06755
gene id: 93221:RO07_RS06755
uniprot id: A0A378Z2F2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

93221:RO07 RS05035
gene id: 93221:RO07_RS05035
uniprot id: A0A378Z368
names: Similarity
messages: Belongs to the type III secretion exporter family.

93221:RO07 RS21755
gene id: 93221:RO07_RS21755
uniprot id: A0A378Z7C9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family.
messages: Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.
messages: Cytoplasm

93221:RO07 RS15555
gene id: 93221:RO07_RS15555
uniprot id: A0A378ZBN4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Homodimer.
messages: Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.

93221:RO07 RS13015
gene id: 93221:RO07_RS13015
uniprot id: A0A379LPC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

93221:RO07 RS26375
gene id: 93221:RO07_RS26375
uniprot id: A0A378ZBE1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

93221:RO07 RS25180
gene id: 93221:RO07_RS25180
uniprot id: A0A378Z5E5
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

93221:RO07 RS25130
gene id: 93221:RO07_RS25130
uniprot id: A0A378Z6Q0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04555
gene id: 93221:RO07_RS04555
uniprot id: A0A378Z3G6
names: Similarity
messages: Belongs to the transglycosylase Slt family.

93221:RO07 RS23640
gene id: 93221:RO07_RS23640
uniprot id: A0A378Z7I6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS4 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S5 and S12 plays an important role in translational accuracy.

93221:RO07 RS04585
gene id: 93221:RO07_RS04585
uniprot id: A0A378Z417
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecD/SecF family. SecD subfamily.
messages: Cell membrane
messages: Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF-YajC and YidC.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.

93221:RO07 RS14055
gene id: 93221:RO07_RS14055
uniprot id: A0A378ZCF7
names: Function
names: Induction
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: By heat shock.
messages: Cytoplasm
messages: Homohexamer. Organized in a ring with a central cavity.

93221:RO07 RS20115
gene id: 93221:RO07_RS20115
uniprot id: A0A378Z8C3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS24230
gene id: 93221:RO07_RS24230
uniprot id: A0A378Z6V4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21725
gene id: 93221:RO07_RS21725
uniprot id: A0A378Z9D8
names: Similarity
messages: Belongs to the N-Me-Phe pilin family.

93221:RO07 RS00250
gene id: 93221:RO07_RS00250
uniprot id: A0A378Z562
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS20720
gene id: 93221:RO07_RS20720
uniprot id: A0A378Z811
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS17065
gene id: 93221:RO07_RS17065
uniprot id: A0A378ZA26
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22595
gene id: 93221:RO07_RS22595
uniprot id: A0A378Z7N6
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS10245
gene id: 93221:RO07_RS10245
uniprot id: A0A378YZA0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS16920
gene id: 93221:RO07_RS16920
uniprot id: A0A378ZC90
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PstS family.
messages: Part of the ABC transporter complex PstSACB involved in phosphate import.
messages: The complex is composed of two ATP-binding proteins (PstB), two transmembrane proteins (PstC and PstA) and a solute-binding protein (PstS).

93221:RO07 RS06950
gene id: 93221:RO07_RS06950
uniprot id: A0A378Z2V4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate:Na(+) symporter (ESS) (TC 2.A.27) family.
messages: Catalyzes the sodium-dependent transport of glutamate.
messages: Cell inner membrane

93221:RO07 RS20165
gene id: 93221:RO07_RS20165
uniprot id: A0A378Z8B3
names: Similarity
messages: Belongs to the UPF0234 family.

93221:RO07 RS11415
gene id: 93221:RO07_RS11415
uniprot id: A0A378Z0V1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family.
messages: Cytoplasm
messages: Homotrimer.

93221:RO07 RS23490
gene id: 93221:RO07_RS23490
uniprot id: A0A378Z6C7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS08695
gene id: 93221:RO07_RS08695
uniprot id: A0A378Z2D6
names: Similarity
messages: Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.

93221:RO07 RS12745
gene id: 93221:RO07_RS12745
uniprot id: A0A379LP61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the invasin protein C family.
messages: Secreted

93221:RO07 RS02495
gene id: 93221:RO07_RS02495
uniprot id: A0A378Z5G7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

93221:RO07 RS11595
gene id: 93221:RO07_RS11595
uniprot id: A0A378YYK0
names: Function
names: Subunit
messages: Catalyzes the synthesis of GMP from XMP.
messages: Homodimer.

93221:RO07 RS03760
gene id: 93221:RO07_RS03760
uniprot id: A0A378Z4H3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10010
gene id: 93221:RO07_RS10010
uniprot id: A0A378YZE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS25265
gene id: 93221:RO07_RS25265
uniprot id: A0A378Z763
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM86 family.
messages: Membrane

93221:RO07 RS04040
gene id: 93221:RO07_RS04040
uniprot id: A0A378Z2W4
names: Similarity
messages: Belongs to the DSD1 family.

93221:RO07 RS07745
gene id: 93221:RO07_RS07745
uniprot id: A0A378Z2X6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00940
gene id: 93221:RO07_RS00940
uniprot id: A0A378Z628
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

93221:RO07 RS03385
gene id: 93221:RO07_RS03385
uniprot id: A0A378Z3B8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22480
gene id: 93221:RO07_RS22480
uniprot id: A0A378Z8Z3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).
messages: Cytoplasm

93221:RO07 RS19125
gene id: 93221:RO07_RS19125
uniprot id: A0A378Z9N8
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS20690
gene id: 93221:RO07_RS20690
uniprot id: A0A378Z8T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Membrane

93221:RO07 RS15470
gene id: 93221:RO07_RS15470
uniprot id: A0A378ZAW1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpC family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

93221:RO07 RS10860
gene id: 93221:RO07_RS10860
uniprot id: A0A378Z159
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RlmJ family.
messages: Monomer.
messages: Specifically methylates the adenine in position 2030 of 23S rRNA.

93221:RO07 RS01680
gene id: 93221:RO07_RS01680
uniprot id: A0A378Z5X5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS18395
gene id: 93221:RO07_RS18395
uniprot id: A0A378ZBC1
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS22770
gene id: 93221:RO07_RS22770
uniprot id: A0A378Z7Z2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06145
gene id: 93221:RO07_RS06145
uniprot id: A0A378Z3M5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

93221:RO07 RS17475
gene id: 93221:RO07_RS17475
uniprot id: A0A378Z9U6
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.

93221:RO07 RS16345
gene id: 93221:RO07_RS16345
uniprot id: A0A378ZAF2
names: Similarity
messages: Belongs to the sulfur carrier protein TusA family.

93221:RO07 RS17795
gene id: 93221:RO07_RS17795
uniprot id: A0A378ZAP3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS05750
gene id: 93221:RO07_RS05750
uniprot id: A0A378Z2Z3
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS03370
gene id: 93221:RO07_RS03370
uniprot id: A0A378Z4Q3
names: Similarity
messages: Belongs to the pirin family.

93221:RO07 RS06205
gene id: 93221:RO07_RS06205
uniprot id: A0A378Z385
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS18560
gene id: 93221:RO07_RS18560
uniprot id: A0A378Z9Z3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HupC/HyaC/HydC family.
messages: Membrane

93221:RO07 RS20020
gene id: 93221:RO07_RS20020
uniprot id: A0A378ZAB8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS05975
gene id: 93221:RO07_RS05975
uniprot id: A0A378Z2Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

93221:RO07 RS00675
gene id: 93221:RO07_RS00675
uniprot id: A0A378Z6G5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptide transporter carbon starvation (CstA) (TC 2.A.114) family.
messages: Membrane

93221:RO07 RS04610
gene id: 93221:RO07_RS04610
uniprot id: A0A378Z2J9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS16565
gene id: 93221:RO07_RS16565
uniprot id: A0A378ZCF6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS19975
gene id: 93221:RO07_RS19975
uniprot id: A0A378ZA69
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

93221:RO07 RS24455
gene id: 93221:RO07_RS24455
uniprot id: A0A378Z6K1
names: Similarity
messages: Belongs to the ArsC family.

93221:RO07 RS15650
gene id: 93221:RO07_RS15650
uniprot id: A0A378ZCV6
names: Similarity
messages: Belongs to the peptidase M20A family. ArgE subfamily.

93221:RO07 RS14070
gene id: 93221:RO07_RS14070
uniprot id: A0A378ZBN9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FKBP-type PPIase family. Tig subfamily.
messages: Consists of 3 domains; the N-terminus binds the ribosome, the middle domain has PPIase activity, while the C-terminus has intrinsic chaperone activity on its own.
messages: Cytoplasm
messages: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase.

93221:RO07 RS18075
gene id: 93221:RO07_RS18075
uniprot id: A0A378Z9H1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17575
gene id: 93221:RO07_RS17575
uniprot id: A0A378ZBW3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04565
gene id: 93221:RO07_RS04565
uniprot id: A0A378Z4S1
names: Function
names: Similarity
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.

93221:RO07 RS06880
gene id: 93221:RO07_RS06880
uniprot id: A0A378Z191
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pantothenate synthetase family.
messages: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.
messages: Cytoplasm
messages: Homodimer.
messages: The reaction proceeds by a bi uni uni bi ping pong mechanism.

93221:RO07 RS08920
gene id: 93221:RO07_RS08920
uniprot id: A0A378Z115
names: Similarity
messages: Belongs to the AlaDH/PNT family.

93221:RO07 RS07305
gene id: 93221:RO07_RS07305
uniprot id: A0A378Z117
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

93221:RO07 RS16810
gene id: 93221:RO07_RS16810
uniprot id: A0A378ZB13
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09750
gene id: 93221:RO07_RS09750
uniprot id: A0A378Z174
names: Similarity
messages: Belongs to the UPF0246 family.

93221:RO07 RS04510
gene id: 93221:RO07_RS04510
uniprot id: A0A378Z2L9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS05925
gene id: 93221:RO07_RS05925
uniprot id: A0A378Z2R3
names: Function
names: Similarity
messages: Belongs to the FlgD family.
messages: Required for flagellar hook formation. May act as a scaffolding protein.

93221:RO07 RS19450
gene id: 93221:RO07_RS19450
uniprot id: A0A378Z9F5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

93221:RO07 RS20550
gene id: 93221:RO07_RS20550
uniprot id: A0A378Z819
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15805
gene id: 93221:RO07_RS15805
uniprot id: A0A378ZCE0
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

93221:RO07 RS23695
gene id: 93221:RO07_RS23695
uniprot id: A0A378Z687
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS8 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.

93221:RO07 RS09580
gene id: 93221:RO07_RS09580
uniprot id: A0A378Z1K8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04385
gene id: 93221:RO07_RS04385
uniprot id: A0A378Z2Q5
names: Similarity
messages: Belongs to the gluconokinase GntK/GntV family.

93221:RO07 RS23355
gene id: 93221:RO07_RS23355
uniprot id: A0A378Z6H4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PRA-CH family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS15310
gene id: 93221:RO07_RS15310
uniprot id: A0A378ZAY7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS15 family.
messages: Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.
messages: Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.

93221:RO07 RS16895
gene id: 93221:RO07_RS16895
uniprot id: A0A378ZA36
names: Function
messages: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

93221:RO07 RS17220
gene id: 93221:RO07_RS17220
uniprot id: A0A378Z9Z4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS01995
gene id: 93221:RO07_RS01995
uniprot id: A0A378Z616
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the dethiobiotin synthetase family.
messages: Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS21840
gene id: 93221:RO07_RS21840
uniprot id: A0A378Z855
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS19605
gene id: 93221:RO07_RS19605
uniprot id: A0A378Z9C0
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS00090
gene id: 93221:RO07_RS00090
uniprot id: A0A378Z6I0
names: Similarity
messages: Belongs to the AHA1 family.

93221:RO07 RS04290
gene id: 93221:RO07_RS04290
uniprot id: A0A378Z2S4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HesB/IscA family.
messages: Binds 1 iron-sulfur cluster per subunit.
messages: Homodimer.
messages: Required for insertion of 4Fe-4S clusters.

93221:RO07 RS08910
gene id: 93221:RO07_RS08910
uniprot id: A0A378Z023
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

93221:RO07 RS00380
gene id: 93221:RO07_RS00380
uniprot id: A0A378Z6W6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the malate synthase family. GlcB subfamily.
messages: Cytoplasm
messages: Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS09105
gene id: 93221:RO07_RS09105
uniprot id: A0A378YZY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MgtC/SapB family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS09865
gene id: 93221:RO07_RS09865
uniprot id: A0A378YZH7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS13715
gene id: 93221:RO07_RS13715
uniprot id: A0A378ZBV9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the homogentisate dioxygenase family.
messages: Hexamer; dimer of trimers.
messages: Involved in the catabolism of homogentisate (2,5-dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS23385
gene id: 93221:RO07_RS23385
uniprot id: A0A378Z7B9
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

93221:RO07 RS20475
gene id: 93221:RO07_RS20475
uniprot id: A0A378Z9K4
names: Similarity
messages: Belongs to the UPF0423 family.

93221:RO07 RS14530
gene id: 93221:RO07_RS14530
uniprot id: A0A378ZC96
names: Function
names: Similarity
messages: Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity.
messages: Belongs to the AhpD family.

93221:RO07 RS09935
gene id: 93221:RO07_RS09935
uniprot id: A0A378Z1N2
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
messages: Homodimer.

93221:RO07 RS05690
gene id: 93221:RO07_RS05690
uniprot id: A0A378Z3S0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS14900
gene id: 93221:RO07_RS14900
uniprot id: A0A378ZD99
names: Similarity
messages: Belongs to the glycosyl hydrolase 24 family.

93221:RO07 RS16015
gene id: 93221:RO07_RS16015
uniprot id: A0A378ZAL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

93221:RO07 RS04180
gene id: 93221:RO07_RS04180
uniprot id: A0A378Z496
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsB sub-subfamily.
messages: Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.
messages: Cell membrane

93221:RO07 RS12840
gene id: 93221:RO07_RS12840
uniprot id: A0A379LP94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YscJ lipoprotein family.
messages: Cell outer membrane
messages: Membrane

93221:RO07 RS09170
gene id: 93221:RO07_RS09170
uniprot id: A0A378YZV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily.
messages: Cell membrane
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

93221:RO07 RS25070
gene id: 93221:RO07_RS25070
uniprot id: A0A378Z709
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase B chain family.
messages: Cell membrane
messages: Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0). The b'-subunit is a diverged and duplicated form of b found in plants and photosynthetic bacteria.
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
messages: Membrane

93221:RO07 RS23735
gene id: 93221:RO07_RS23735
uniprot id: A0A378Z748
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS3 family.
messages: Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.
messages: Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.

93221:RO07 RS22685
gene id: 93221:RO07_RS22685
uniprot id: A0A378Z6V5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbC subfamily.
messages: Periplasm
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process.

93221:RO07 RS08620
gene id: 93221:RO07_RS08620
uniprot id: A0A378Z0G7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS19920
gene id: 93221:RO07_RS19920
uniprot id: A0A378Z9W6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24420
gene id: 93221:RO07_RS24420
uniprot id: A0A378Z7D7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmI family.
messages: Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
messages: Cytoplasm

93221:RO07 RS23925
gene id: 93221:RO07_RS23925
uniprot id: A0A378Z7M0
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SecE/SEC61-gamma family.
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS09900
gene id: 93221:RO07_RS09900
uniprot id: A0A378Z0L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpA family.
messages: Tetramer of two alpha and two beta chains.
messages: The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.

93221:RO07 RS15645
gene id: 93221:RO07_RS15645
uniprot id: A0A378ZAU7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15170
gene id: 93221:RO07_RS15170
uniprot id: A0A378ZCJ1
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit A family.

93221:RO07 RS03050
gene id: 93221:RO07_RS03050
uniprot id: A0A378Z5E4
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M20 family.
messages: Binds 2 Zn(2+) ions per subunit.

93221:RO07 RS19360
gene id: 93221:RO07_RS19360
uniprot id: A0A378ZAR2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS08185
gene id: 93221:RO07_RS08185
uniprot id: A0A378Z0Q2
names: Similarity
messages: Belongs to the ketopantoate reductase family.

93221:RO07 RS19810
gene id: 93221:RO07_RS19810
uniprot id: A0A378Z8I5
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS22865
gene id: 93221:RO07_RS22865
uniprot id: A0A378Z7X5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

93221:RO07 RS03200
gene id: 93221:RO07_RS03200
uniprot id: A0A378Z5B2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS20280
gene id: 93221:RO07_RS20280
uniprot id: A0A378ZA15
names: Function
names: Similarity
messages: Belongs to the HPPK family.
messages: Catalyzes the transfer of pyrophosphate from adenosine triphosphate (ATP) to 6-hydroxymethyl-7,8-dihydropterin, an enzymatic step in folate biosynthesis pathway.

93221:RO07 RS08375
gene id: 93221:RO07_RS08375
uniprot id: A0A378Z2C5
names: Function
messages: Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

93221:RO07 RS13695
gene id: 93221:RO07_RS13695
uniprot id: A0A378ZDI9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Transforms N(2)-succinylglutamate into succinate and glutamate.

93221:RO07 RS05605
gene id: 93221:RO07_RS05605
uniprot id: A0A378Z315
names: PTM
names: Similarity
names: Subunit
messages: Belongs to the gamma-glutamyltransferase family.
messages: Cleaved by autocatalysis into a large and a small subunit.
messages: This enzyme consists of two polypeptide chains, which are synthesized in precursor form from a single polypeptide.

93221:RO07 RS05045
gene id: 93221:RO07_RS05045
uniprot id: A0A378Z4H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

93221:RO07 RS04535
gene id: 93221:RO07_RS04535
uniprot id: A0A378Z426
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS20450
gene id: 93221:RO07_RS20450
uniprot id: A0A378Z831
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pyrroline-5-carboxylate reductase family.
messages: Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
messages: Cytoplasm

93221:RO07 RS00700
gene id: 93221:RO07_RS00700
uniprot id: A0A378Z4W7
names: Similarity
messages: Belongs to the type IA topoisomerase family.

93221:RO07 RS00345
gene id: 93221:RO07_RS00345
uniprot id: A0A378Z537
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

93221:RO07 RS15480
gene id: 93221:RO07_RS15480
uniprot id: A0A378ZAW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KdpA family.
messages: Cell membrane
messages: Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds the extracellular potassium ions and delivers the ions to the membrane domain of KdpB through an intramembrane tunnel.
messages: The system is composed of three essential subunits: KdpA, KdpB and KdpC.

93221:RO07 RS01570
gene id: 93221:RO07_RS01570
uniprot id: A0A378Z6G1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS19145
gene id: 93221:RO07_RS19145
uniprot id: A0A378Z8V4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS13085
gene id: 93221:RO07_RS13085
uniprot id: A0A379LPU4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS05590
gene id: 93221:RO07_RS05590
uniprot id: A0A378Z477
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nlpA lipoprotein family.
messages: Membrane

93221:RO07 RS09405
gene id: 93221:RO07_RS09405
uniprot id: A0A378Z0R4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS17165
gene id: 93221:RO07_RS17165
uniprot id: A0A378ZAU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family. Azg-like subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS17360
gene id: 93221:RO07_RS17360
uniprot id: A0A378Z9W2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DsbB family.
messages: Cell inner membrane
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein.

93221:RO07 RS06275
gene id: 93221:RO07_RS06275
uniprot id: A0A378Z2K0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LemA family.
messages: Membrane

93221:RO07 RS02580
gene id: 93221:RO07_RS02580
uniprot id: A0A378Z3T9
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.
messages: Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.
messages: Cell membrane
messages: Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
messages: Membrane

93221:RO07 RS11170
gene id: 93221:RO07_RS11170
uniprot id: A0A378Z101
names: Similarity
messages: Belongs to the UPF0111 family.

93221:RO07 RS07870
gene id: 93221:RO07_RS07870
uniprot id: A0A378Z2B4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23570
gene id: 93221:RO07_RS23570
uniprot id: A0A378Z7U7
names: Function
names: Similarity
messages: Belongs to the frataxin family.
messages: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.

93221:RO07 RS04570
gene id: 93221:RO07_RS04570
uniprot id: A0A378Z4B1
names: PTM
messages: Binds 1 heme group per subunit.

93221:RO07 RS01290
gene id: 93221:RO07_RS01290
uniprot id: A0A378Z5W2
names: Cofactor
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family.
messages: Binds 2 nickel ions per subunit.
messages: Carbamylation allows a single lysine to coordinate two nickel ions.
messages: Carboxylation allows a single lysine to coordinate two nickel ions.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

93221:RO07 RS06935
gene id: 93221:RO07_RS06935
uniprot id: A0A378Z3G5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.
messages: Homodimer.
messages: In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.
messages: In the N-terminal section; belongs to the MIP18 family.

93221:RO07 RS06965
gene id: 93221:RO07_RS06965
uniprot id: A0A378Z1F2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PEPCase type 1 family.
messages: Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
messages: Homotetramer.

93221:RO07 RS12090
gene id: 93221:RO07_RS12090
uniprot id: A0A378YZ99
names: Similarity
messages: Belongs to the leucine-binding protein family.

93221:RO07 RS21700
gene id: 93221:RO07_RS21700
uniprot id: A0A378Z7D9
names: Similarity
messages: Belongs to the UPF0301 (AlgH) family.

93221:RO07 RS18615
gene id: 93221:RO07_RS18615
uniprot id: A0A378ZA86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

93221:RO07 RS24165
gene id: 93221:RO07_RS24165
uniprot id: A0A378Z804
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LPG synthase family.
messages: Membrane

93221:RO07 RS07080
gene id: 93221:RO07_RS07080
uniprot id: A0A378Z353
names: Function
names: Similarity
messages: Belongs to the NAD synthetase family.
messages: Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
messages: In the C-terminal section; belongs to the NAD synthetase family.

93221:RO07 RS06140
gene id: 93221:RO07_RS06140
uniprot id: A0A378Z3J5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS21945
gene id: 93221:RO07_RS21945
uniprot id: A0A378Z835
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the methylthiotransferase family. MiaB subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS10280
gene id: 93221:RO07_RS10280
uniprot id: A0A378YZA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BI1 family.
messages: Membrane

93221:RO07 RS15990
gene id: 93221:RO07_RS15990
uniprot id: A0A378ZCP3
names: Similarity
messages: Belongs to the PrpF family.

93221:RO07 RS19350
gene id: 93221:RO07_RS19350
uniprot id: A0A378Z9H5
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.

93221:RO07 RS23775
gene id: 93221:RO07_RS23775
uniprot id: A0A378Z7Q4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: Cytoplasm
messages: Monomer.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

93221:RO07 RS20400
gene id: 93221:RO07_RS20400
uniprot id: A0A378Z841
names: Function
names: Similarity
messages: Belongs to the class-I DAHP synthase family.
messages: Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).

93221:RO07 RS09150
gene id: 93221:RO07_RS09150
uniprot id: A0A378YZX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. Uup subfamily.
messages: Cytoplasm
messages: Probably plays a role in ribosome assembly or function. May be involved in resolution of branched DNA intermediates that result from template switching in postreplication gaps. Binds DNA and has ATPase activity.

93221:RO07 RS23740
gene id: 93221:RO07_RS23740
uniprot id: A0A378Z7G0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL22 family.
messages: Part of the 50S ribosomal subunit.
messages: The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.

93221:RO07 RS10695
gene id: 93221:RO07_RS10695
uniprot id: A0A378Z183
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

93221:RO07 RS20110
gene id: 93221:RO07_RS20110
uniprot id: A0A378Z921
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS01905
gene id: 93221:RO07_RS01905
uniprot id: A0A378Z5K3
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family.

93221:RO07 RS04685
gene id: 93221:RO07_RS04685
uniprot id: A0A378Z2J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterioferritin family.
messages: Iron-storage protein.
messages: Oligomer of 24 subunits, arranged as 12 dimers, that are packed together to form an approximately spherical molecule with a central cavity, in which large amounts of iron can be deposited.

93221:RO07 RS22670
gene id: 93221:RO07_RS22670
uniprot id: A0A378Z810
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Also exhibits azoreductase activity. Catalyzes the reductive cleavage of the azo bond in aromatic azo compounds to the corresponding amines.
messages: Belongs to the azoreductase type 1 family.
messages: Binds 1 FMN per subunit.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Quinone reductase that provides resistance to thiol-specific stress caused by electrophilic quinones.

93221:RO07 RS06310
gene id: 93221:RO07_RS06310
uniprot id: A0A378Z1N4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

93221:RO07 RS22245
gene id: 93221:RO07_RS22245
uniprot id: A0A378Z7X9
names: Function
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

93221:RO07 RS23435
gene id: 93221:RO07_RS23435
uniprot id: A0A378Z7M1
names: Similarity
messages: Belongs to the MlaA family.

93221:RO07 RS22120
gene id: 93221:RO07_RS22120
uniprot id: A0A378Z7Y5
names: Similarity
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.

93221:RO07 RS12965
gene id: 93221:RO07_RS12965
uniprot id: A0A379LPA8
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS24080
gene id: 93221:RO07_RS24080
uniprot id: A0A378Z6Y2
names: Similarity
messages: Belongs to the malic enzymes family.
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

93221:RO07 RS06115
gene id: 93221:RO07_RS06115
uniprot id: A0A378Z1Q5
names: Caution
names: Similarity
messages: Belongs to the UPF0391 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS24745
gene id: 93221:RO07_RS24745
uniprot id: A0A378Z6D2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

93221:RO07 RS02180
gene id: 93221:RO07_RS02180
uniprot id: A0A378Z446
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS04340
gene id: 93221:RO07_RS04340
uniprot id: A0A378Z2R4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvB family.
messages: Forms a complex with RuvA.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.

93221:RO07 RS12770
gene id: 93221:RO07_RS12770
uniprot id: A0A379LQQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

93221:RO07 RS04205
gene id: 93221:RO07_RS04205
uniprot id: A0A378Z2T7
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS16035
gene id: 93221:RO07_RS16035
uniprot id: A0A378ZCN3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS06700
gene id: 93221:RO07_RS06700
uniprot id: A0A378Z3C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LapB family.
messages: Cell inner membrane
messages: Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane.

93221:RO07 RS01350
gene id: 93221:RO07_RS01350
uniprot id: A0A378Z4I8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15005
gene id: 93221:RO07_RS15005
uniprot id: A0A378ZD83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS22585
gene id: 93221:RO07_RS22585
uniprot id: A0A378Z6X3
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS25125
gene id: 93221:RO07_RS25125
uniprot id: A0A378Z6C3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS10395
gene id: 93221:RO07_RS10395
uniprot id: A0A378YZ74
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 2 lipoyl cofactors covalently.
messages: Forms a 24-polypeptide structural core with octahedral symmetry.
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).

93221:RO07 RS03090
gene id: 93221:RO07_RS03090
uniprot id: A0A378Z5L6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS20375
gene id: 93221:RO07_RS20375
uniprot id: A0A378Z9M5
names: Function
names: Similarity
messages: Belongs to the RecN family.
messages: May be involved in recombinational repair of damaged DNA.

93221:RO07 RS10310
gene id: 93221:RO07_RS10310
uniprot id: A0A378Z198
names: Similarity
messages: Belongs to the YfgM family.

93221:RO07 RS17690
gene id: 93221:RO07_RS17690
uniprot id: A0A378ZAG6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21340
gene id: 93221:RO07_RS21340
uniprot id: A0A378Z7P7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0324 family.
messages: Membrane

93221:RO07 RS19870
gene id: 93221:RO07_RS19870
uniprot id: A0A378Z9X6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS12760
gene id: 93221:RO07_RS12760
uniprot id: A0A379LPB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the type III secretion exporter family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10300
gene id: 93221:RO07_RS10300
uniprot id: A0A378Z1G7
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspG family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.

93221:RO07 RS19495
gene id: 93221:RO07_RS19495
uniprot id: A0A378Z8N8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Maf family. YhdE subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.

93221:RO07 RS01825
gene id: 93221:RO07_RS01825
uniprot id: A0A378Z522
names: Similarity
messages: Belongs to the IMPACT family.

93221:RO07 RS12255
gene id: 93221:RO07_RS12255
uniprot id: A0A378Z094
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the encapsulin family. Family 1 subfamily.
messages: Encapsulin nanocompartment

93221:RO07 RS25025
gene id: 93221:RO07_RS25025
uniprot id: A0A378Z7B2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FlhD family.
messages: Cytoplasm
messages: Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways.
messages: Homodimer; disulfide-linked. Forms a heterohexamer composed of two FlhC and four FlhD subunits. Each FlhC binds a FlhD dimer, forming a heterotrimer, and a hexamer assembles by dimerization of two heterotrimers.
messages: The C-terminal region contains a putative helix-turn-helix (HTH) motif, suggesting that this region may bind DNA.

93221:RO07 RS10985
gene id: 93221:RO07_RS10985
uniprot id: A0A378Z009
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

93221:RO07 RS09710
gene id: 93221:RO07_RS09710
uniprot id: A0A378YZK5
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS06655
gene id: 93221:RO07_RS06655
uniprot id: A0A378Z2H2
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS15120
gene id: 93221:RO07_RS15120
uniprot id: A0A378ZCS9
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL20 family.
messages: Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.

93221:RO07 RS02045
gene id: 93221:RO07_RS02045
uniprot id: A0A378Z603
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AceK family.
messages: Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation.
messages: Cytoplasm

93221:RO07 RS02540
gene id: 93221:RO07_RS02540
uniprot id: A0A378Z5X4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Cell membrane
messages: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
messages: Membrane

93221:RO07 RS05635
gene id: 93221:RO07_RS05635
uniprot id: A0A378Z1Y5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the heme-copper respiratory oxidase family.
messages: Membrane

93221:RO07 RS20490
gene id: 93221:RO07_RS20490
uniprot id: A0A378Z8W5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS25080
gene id: 93221:RO07_RS25080
uniprot id: A0A378Z6D4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase A chain family.
messages: Cell membrane
messages: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.
messages: Membrane

93221:RO07 RS11065
gene id: 93221:RO07_RS11065
uniprot id: A0A378YYV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

93221:RO07 RS17805
gene id: 93221:RO07_RS17805
uniprot id: A0A378Z9M6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

93221:RO07 RS23175
gene id: 93221:RO07_RS23175
uniprot id: A0A378Z7S0
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 2 family.

93221:RO07 RS03810
gene id: 93221:RO07_RS03810
uniprot id: A0A378Z4G3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS12890
gene id: 93221:RO07_RS12890
uniprot id: A0A379LP90
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13720
gene id: 93221:RO07_RS13720
uniprot id: A0A378ZCQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22400
gene id: 93221:RO07_RS22400
uniprot id: A0A378Z861
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CoaE family.
messages: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.
messages: Cytoplasm

93221:RO07 RS22105
gene id: 93221:RO07_RS22105
uniprot id: A0A378Z762
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Fur family.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS06570
gene id: 93221:RO07_RS06570
uniprot id: A0A378Z1G4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the IlvD/Edd family.
messages: Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.
messages: Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS15235
gene id: 93221:RO07_RS15235
uniprot id: A0A378ZC38
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0761 family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS19610
gene id: 93221:RO07_RS19610
uniprot id: A0A378Z8M8
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ThiC family.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction.
messages: Homodimer.

93221:RO07 RS25150
gene id: 93221:RO07_RS25150
uniprot id: A0A378Z5F4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20075
gene id: 93221:RO07_RS20075
uniprot id: A0A378Z9T2
names: Function
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

93221:RO07 RS09155
gene id: 93221:RO07_RS09155
uniprot id: A0A378YZX0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family. ParE type 1 subfamily.
messages: Heterotetramer composed of ParC and ParE.
messages: Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.

93221:RO07 RS02900
gene id: 93221:RO07_RS02900
uniprot id: A0A378Z582
names: Function
names: Similarity
messages: Belongs to the PurU family.
messages: Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).

93221:RO07 RS10020
gene id: 93221:RO07_RS10020
uniprot id: A0A378YZN9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
messages: Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS09795
gene id: 93221:RO07_RS09795
uniprot id: A0A378Z0N6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.

93221:RO07 RS06360
gene id: 93221:RO07_RS06360
uniprot id: A0A378Z1M5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS19025
gene id: 93221:RO07_RS19025
uniprot id: A0A378Z9Q0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS19945
gene id: 93221:RO07_RS19945
uniprot id: A0A378Z8D2
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
messages: Cytoplasm
messages: IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).
messages: Monomer.

93221:RO07 RS08450
gene id: 93221:RO07_RS08450
uniprot id: A0A378Z1G0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate.

93221:RO07 RS20250
gene id: 93221:RO07_RS20250
uniprot id: A0A378Z869
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04670
gene id: 93221:RO07_RS04670
uniprot id: A0A378Z4G7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB family.
messages: Cell inner membrane

93221:RO07 RS20465
gene id: 93221:RO07_RS20465
uniprot id: A0A378Z856
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

93221:RO07 RS17020
gene id: 93221:RO07_RS17020
uniprot id: A0A378ZC70
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS24810
gene id: 93221:RO07_RS24810
uniprot id: A0A378Z760
names: Function
names: Similarity
messages: Belongs to the FliK family.
messages: Controls the length of the flagellar hook.

93221:RO07 RS11120
gene id: 93221:RO07_RS11120
uniprot id: A0A378Z108
names: Similarity
messages: Belongs to the asparaginase 1 family.

93221:RO07 RS22740
gene id: 93221:RO07_RS22740
uniprot id: A0A378Z7J7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22855
gene id: 93221:RO07_RS22855
uniprot id: A0A378Z8K1
names: Caution
names: Similarity
messages: Belongs to the acylphosphatase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS17145
gene id: 93221:RO07_RS17145
uniprot id: A0A378ZB12
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24895
gene id: 93221:RO07_RS24895
uniprot id: A0A378Z6A6
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93221:RO07 RS17520
gene id: 93221:RO07_RS17520
uniprot id: A0A378ZAM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS13175
gene id: 93221:RO07_RS13175
uniprot id: A0A378ZC67
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10350
gene id: 93221:RO07_RS10350
uniprot id: A0A378Z1F6
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. HisZ subfamily.
messages: Cytoplasm
messages: Heteromultimer composed of HisG and HisZ subunits.
messages: Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
messages: This function is generally fulfilled by the C-terminal part of HisG, which is missing in some bacteria such as this one.

93221:RO07 RS00415
gene id: 93221:RO07_RS00415
uniprot id: A0A378Z533
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS12920
gene id: 93221:RO07_RS12920
uniprot id: A0A379LP98
names: Similarity
messages: Belongs to the disproportionating enzyme family.

93221:RO07 RS08690
gene id: 93221:RO07_RS08690
uniprot id: A0A378Z066
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ExbB/TolQ family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93221:RO07 RS09000
gene id: 93221:RO07_RS09000
uniprot id: A0A378Z1N6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
messages: Belongs to the oligoribonuclease family.
messages: Cytoplasm

93221:RO07 RS18490
gene id: 93221:RO07_RS18490
uniprot id: A0A378Z997
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS06230
gene id: 93221:RO07_RS06230
uniprot id: A0A378Z1M9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22440
gene id: 93221:RO07_RS22440
uniprot id: A0A378Z8T6
names: Function
names: Similarity
messages: Belongs to the LpxC family.
messages: Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.

93221:RO07 RS05260
gene id: 93221:RO07_RS05260
uniprot id: A0A378Z445
names: Similarity
messages: Belongs to the myoviridae tail sheath protein family.

93221:RO07 RS16710
gene id: 93221:RO07_RS16710
uniprot id: A0A378ZA97
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS18525
gene id: 93221:RO07_RS18525
uniprot id: A0A378Z979
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS04235
gene id: 93221:RO07_RS04235
uniprot id: A0A378Z2T4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS11130
gene id: 93221:RO07_RS11130
uniprot id: A0A378Z0V3
names: Similarity
messages: Belongs to the hyi family.

93221:RO07 RS05760
gene id: 93221:RO07_RS05760
uniprot id: A0A378Z1Z5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21265
gene id: 93221:RO07_RS21265
uniprot id: A0A378Z8H1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS16960
gene id: 93221:RO07_RS16960
uniprot id: A0A378ZAY6
names: Caution
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the CarB family.
messages: Binds 4 Mg(2+) or Mn(2+) ions per subunit.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS03340
gene id: 93221:RO07_RS03340
uniprot id: A0A378Z450
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS05920
gene id: 93221:RO07_RS05920
uniprot id: A0A378Z207
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93221:RO07 RS24415
gene id: 93221:RO07_RS24415
uniprot id: A0A378Z7U0
names: Similarity
messages: Belongs to the UPF0102 family.

93221:RO07 RS18625
gene id: 93221:RO07_RS18625
uniprot id: A0A378Z957
names: Function
names: Similarity
messages: Belongs to the AIR carboxylase family. Class I subfamily.
messages: Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).

93221:RO07 RS04240
gene id: 93221:RO07_RS04240
uniprot id: A0A378Z2R9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS00810
gene id: 93221:RO07_RS00810
uniprot id: A0A378Z5K5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsA/MreB family.
messages: Cytoplasm
messages: Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.
messages: Forms polymers.

93221:RO07 RS21640
gene id: 93221:RO07_RS21640
uniprot id: A0A378Z895
names: Similarity
messages: Belongs to the phosphohexose mutase family.

93221:RO07 RS05860
gene id: 93221:RO07_RS05860
uniprot id: A0A378Z1X5
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS10645
gene id: 93221:RO07_RS10645
uniprot id: A0A378YZ21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the auxin efflux carrier (TC 2.A.69) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS19995
gene id: 93221:RO07_RS19995
uniprot id: A0A378Z8D0
names: Similarity
messages: Belongs to the bacterial ring-hydroxylating dioxygenase beta subunit family.

93221:RO07 RS06400
gene id: 93221:RO07_RS06400
uniprot id: A0A378Z350
names: Similarity
messages: Belongs to the glutathione peroxidase family.

93221:RO07 RS06060
gene id: 93221:RO07_RS06060
uniprot id: A0A378Z1T4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10250
gene id: 93221:RO07_RS10250
uniprot id: A0A378Z1H6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SurE nucleotidase family.
messages: Binds 1 divalent metal cation per subunit.
messages: Cytoplasm
messages: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.

93221:RO07 RS07410
gene id: 93221:RO07_RS07410
uniprot id: A0A378Z161
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS24295
gene id: 93221:RO07_RS24295
uniprot id: A0A378Z5Y1
names: Similarity
messages: Belongs to the DegT/DnrJ/EryC1 family.

93221:RO07 RS01305
gene id: 93221:RO07_RS01305
uniprot id: A0A378Z4J2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the urease gamma subunit family.
messages: Cytoplasm
messages: Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.

93221:RO07 RS01485
gene id: 93221:RO07_RS01485
uniprot id: A0A378Z5S5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS10405
gene id: 93221:RO07_RS10405
uniprot id: A0A378Z142
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

93221:RO07 RS02345
gene id: 93221:RO07_RS02345
uniprot id: A0A378Z5K4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
messages: Cell membrane
messages: Membrane
messages: Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane.

93221:RO07 RS02690
gene id: 93221:RO07_RS02690
uniprot id: A0A378Z5U4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
messages: Binds 2 Mg(2+) ions per subunit.
messages: Cytoplasm
messages: Homohexamer.
messages: Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).

93221:RO07 RS13335
gene id: 93221:RO07_RS13335
uniprot id: A0A378ZE64
names: Similarity
messages: Belongs to the Gfa family.

93221:RO07 RS21485
gene id: 93221:RO07_RS21485
uniprot id: A0A378Z7L7
names: Similarity
messages: Belongs to the Gfa family.

93221:RO07 RS06940
gene id: 93221:RO07_RS06940
uniprot id: A0A378Z379
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dCTP deaminase family.
messages: Catalyzes the deamination of dCTP to dUTP.
messages: Homotrimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS01230
gene id: 93221:RO07_RS01230
uniprot id: A0A378Z6F3
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

93221:RO07 RS00465
gene id: 93221:RO07_RS00465
uniprot id: A0A378Z521
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS05930
gene id: 93221:RO07_RS05930
uniprot id: A0A378Z1S9
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS17075
gene id: 93221:RO07_RS17075
uniprot id: A0A378ZBJ4
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21305
gene id: 93221:RO07_RS21305
uniprot id: A0A378Z944
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS16155
gene id: 93221:RO07_RS16155
uniprot id: A0A378ZAH5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22610
gene id: 93221:RO07_RS22610
uniprot id: A0A378Z8F7
names: Function
names: Similarity
messages: Belongs to the phenylacetyl-CoA ligase family.
messages: Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA).

93221:RO07 RS00280
gene id: 93221:RO07_RS00280
uniprot id: A0A378Z6N8
names: Similarity
messages: Belongs to the class-C beta-lactamase family.

93221:RO07 RS10375
gene id: 93221:RO07_RS10375
uniprot id: A0A378YZ79
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.
messages: Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS02410
gene id: 93221:RO07_RS02410
uniprot id: A0A378Z5A5
names: Similarity
messages: Belongs to the prokaryotic GSH synthase family.

93221:RO07 RS16250
gene id: 93221:RO07_RS16250
uniprot id: A0A378ZBB3
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

93221:RO07 RS25270
gene id: 93221:RO07_RS25270
uniprot id: A0A378Z691
names: Similarity
messages: Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.

93221:RO07 RS07035
gene id: 93221:RO07_RS07035
uniprot id: A0A378Z294
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
messages: Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.
messages: The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).

93221:RO07 RS06350
gene id: 93221:RO07_RS06350
uniprot id: A0A378Z2M3
names: Function
names: Similarity
messages: Belongs to the AMP nucleosidase family.
messages: Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.

93221:RO07 RS14225
gene id: 93221:RO07_RS14225
uniprot id: A0A378ZBJ6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Monomer.
messages: Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.

93221:RO07 RS21435
gene id: 93221:RO07_RS21435
uniprot id: A0A378Z7M7
names: Similarity
messages: Belongs to the AHA1 family.

93221:RO07 RS02005
gene id: 93221:RO07_RS02005
uniprot id: A0A378Z5I3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
messages: Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS03720
gene id: 93221:RO07_RS03720
uniprot id: A0A378Z333
names: Similarity
messages: Belongs to the HMG-CoA lyase family.

93221:RO07 RS15045
gene id: 93221:RO07_RS15045
uniprot id: A0A378ZB38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM175 family.
messages: Membrane

93221:RO07 RS06690
gene id: 93221:RO07_RS06690
uniprot id: A0A378Z3L0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the bacterial histone-like protein family.
messages: Heterodimer of an alpha and a beta chain.
messages: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.

93221:RO07 RS19530
gene id: 93221:RO07_RS19530
uniprot id: A0A378Z9Q9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23360
gene id: 93221:RO07_RS23360
uniprot id: A0A378Z771
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.

93221:RO07 RS23665
gene id: 93221:RO07_RS23665
uniprot id: A0A378Z6A7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecY/SEC61-alpha family.
messages: Cell membrane
messages: Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.
messages: Membrane
messages: The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.

93221:RO07 RS14640
gene id: 93221:RO07_RS14640
uniprot id: A0A378ZDE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the BamD family.
messages: Cell outer membrane
messages: Part of the Bam complex.
messages: Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.

93221:RO07 RS08235
gene id: 93221:RO07_RS08235
uniprot id: A0A378Z0N9
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CoA-transferase III family. Frc subfamily.
messages: Homodimer.
messages: Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS11140
gene id: 93221:RO07_RS11140
uniprot id: A0A378Z0I5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS07475
gene id: 93221:RO07_RS07475
uniprot id: A0A378Z345
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS01225
gene id: 93221:RO07_RS01225
uniprot id: A0A378Z661
names: Similarity
messages: Belongs to the TlyA family.

93221:RO07 RS04190
gene id: 93221:RO07_RS04190
uniprot id: A0A378Z2S9
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS24820
gene id: 93221:RO07_RS24820
uniprot id: A0A378Z6I6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliM family.
messages: Cell inner membrane
messages: FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
messages: Membrane

93221:RO07 RS01120
gene id: 93221:RO07_RS01120
uniprot id: A0A378Z6N9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS08660
gene id: 93221:RO07_RS08660
uniprot id: A0A378Z1C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

93221:RO07 RS06705
gene id: 93221:RO07_RS06705
uniprot id: A0A378Z2G0
names: Similarity
messages: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

93221:RO07 RS04355
gene id: 93221:RO07_RS04355
uniprot id: A0A378Z3K9
names: Similarity
messages: Belongs to the GST superfamily. NadH family.

93221:RO07 RS13865
gene id: 93221:RO07_RS13865
uniprot id: A0A378ZBT4
names: Similarity
messages: Belongs to the acylphosphatase family.

93221:RO07 RS15280
gene id: 93221:RO07_RS15280
uniprot id: A0A378ZBT1
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

93221:RO07 RS02760
gene id: 93221:RO07_RS02760
uniprot id: A0A378Z4L9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LptA family.
messages: Component of the lipopolysaccharide transport and assembly complex.
messages: Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
messages: Periplasm

93221:RO07 RS23880
gene id: 93221:RO07_RS23880
uniprot id: A0A378Z7Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

93221:RO07 RS10110
gene id: 93221:RO07_RS10110
uniprot id: A0A378Z0G6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS14810
gene id: 93221:RO07_RS14810
uniprot id: A0A378ZCB4
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Alpha(8)-beta(8). The alpha component is a flavoprotein, the beta component is a hemoprotein.
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Binds 1 siroheme per subunit.
messages: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate.

93221:RO07 RS11075
gene id: 93221:RO07_RS11075
uniprot id: A0A378Z0R6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS15925
gene id: 93221:RO07_RS15925
uniprot id: A0A378ZAN5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 2 family.
messages: Membrane

93221:RO07 RS22350
gene id: 93221:RO07_RS22350
uniprot id: A0A378Z707
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glutamate 5-kinase family.
messages: Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS23445
gene id: 93221:RO07_RS23445
uniprot id: A0A378Z6E7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MlaE permease family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS17395
gene id: 93221:RO07_RS17395
uniprot id: A0A378ZAM6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.

93221:RO07 RS24855
gene id: 93221:RO07_RS24855
uniprot id: A0A378Z7K6
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

93221:RO07 RS22970
gene id: 93221:RO07_RS22970
uniprot id: A0A378Z7W1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family.
messages: Membrane

93221:RO07 RS09050
gene id: 93221:RO07_RS09050
uniprot id: A0A378Z1M4
names: Function
names: Similarity
messages: Belongs to the dihydrofolate reductase family.
messages: Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

93221:RO07 RS10940
gene id: 93221:RO07_RS10940
uniprot id: A0A378Z0L8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ribose 5-phosphate isomerase family.
messages: Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
messages: Homodimer.

93221:RO07 RS07530
gene id: 93221:RO07_RS07530
uniprot id: A0A378Z2S5
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS24555
gene id: 93221:RO07_RS24555
uniprot id: A0A378Z6H8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GcvT family.
messages: The glycine cleavage system catalyzes the degradation of glycine.
messages: The glycine cleavage system is composed of four proteins: P, T, L and H.

93221:RO07 RS08115
gene id: 93221:RO07_RS08115
uniprot id: A0A378Z2H8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS11015
gene id: 93221:RO07_RS11015
uniprot id: A0A378YYV8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RimP family.
messages: Cytoplasm
messages: Required for maturation of 30S ribosomal subunits.

93221:RO07 RS17970
gene id: 93221:RO07_RS17970
uniprot id: A0A378ZBK8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS11790
gene id: 93221:RO07_RS11790
uniprot id: A0A378Z061
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93221:RO07 RS23865
gene id: 93221:RO07_RS23865
uniprot id: A0A378Z665
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS16915
gene id: 93221:RO07_RS16915
uniprot id: A0A378ZA57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.

93221:RO07 RS03080
gene id: 93221:RO07_RS03080
uniprot id: A0A378Z4A4
names: Similarity
names: Subunit
messages: Belongs to the aldehyde dehydrogenase family.
messages: Homotetramer.

93221:RO07 RS12000
gene id: 93221:RO07_RS12000
uniprot id: A0A378YYC8
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Maintains high levels of reduced glutathione.

93221:RO07 RS05870
gene id: 93221:RO07_RS05870
uniprot id: A0A378Z215
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

93221:RO07 RS03660
gene id: 93221:RO07_RS03660
uniprot id: A0A378Z4J7
names: Similarity
messages: Belongs to the phosphate acetyltransferase and butyryltransferase family.

93221:RO07 RS04110
gene id: 93221:RO07_RS04110
uniprot id: A0A378Z516
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
messages: Cell inner membrane
messages: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.

93221:RO07 RS04890
gene id: 93221:RO07_RS04890
uniprot id: A0A378Z2F4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum
messages: Belongs to the FliD family.
messages: Homopentamer.
messages: Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
messages: Secreted

93221:RO07 RS11025
gene id: 93221:RO07_RS11025
uniprot id: A0A378Z0S6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

93221:RO07 RS05625
gene id: 93221:RO07_RS05625
uniprot id: A0A378Z263
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase bacterial subunit 4 family.
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

93221:RO07 RS24090
gene id: 93221:RO07_RS24090
uniprot id: A0A378Z615
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS17825
gene id: 93221:RO07_RS17825
uniprot id: A0A378ZB51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. FtsI subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.
messages: Cell inner membrane

93221:RO07 RS14120
gene id: 93221:RO07_RS14120
uniprot id: A0A378ZBL6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the MinC family.
messages: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.
messages: Interacts with MinD and FtsZ.

93221:RO07 RS06325
gene id: 93221:RO07_RS06325
uniprot id: A0A378Z2I5
names: Caution
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS23325
gene id: 93221:RO07_RS23325
uniprot id: A0A378Z802
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TatC family.
messages: Cell membrane
messages: Membrane
messages: Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides.
messages: The Tat system comprises two distinct complexes: a TatABC complex, containing multiple copies of TatA, TatB and TatC subunits, and a separate TatA complex, containing only TatA subunits. Substrates initially bind to the TatABC complex, which probably triggers association of the separate TatA complex to form the active translocon.

93221:RO07 RS09055
gene id: 93221:RO07_RS09055
uniprot id: A0A378Z003
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.
messages: Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS23645
gene id: 93221:RO07_RS23645
uniprot id: A0A378Z697
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS11 family.
messages: Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.
messages: Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.

93221:RO07 RS22190
gene id: 93221:RO07_RS22190
uniprot id: A0A378Z8Y4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscS (TC 1.A.23) family.
messages: Cell inner membrane
messages: Homoheptamer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mechanosensitive channel that participates in the regulation of osmotic pressure changes within the cell, opening in response to stretch forces in the membrane lipid bilayer, without the need for other proteins. Contributes to normal resistance to hypoosmotic shock. Forms an ion channel of 1.0 nanosiemens conductance with a slight preference for anions.
messages: Membrane

93221:RO07 RS13990
gene id: 93221:RO07_RS13990
uniprot id: A0A378ZDC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YciB family.
messages: Cell inner membrane
messages: Plays a role in cell envelope biogenesis, maintenance of cell envelope integrity and membrane homeostasis.

93221:RO07 RS22835
gene id: 93221:RO07_RS22835
uniprot id: A0A378Z7H6
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.
messages: Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).
messages: The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.
messages: The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.

93221:RO07 RS10320
gene id: 93221:RO07_RS10320
uniprot id: A0A378Z0Y0
names: Function
names: Similarity
names: Subunit
messages: Associates with the 50S ribosomal subunit.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
messages: GTPase that plays an essential role in the late steps of ribosome biogenesis.

93221:RO07 RS20295
gene id: 93221:RO07_RS20295
uniprot id: A0A378Z868
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS13980
gene id: 93221:RO07_RS13980
uniprot id: A0A378ZDT3
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.

93221:RO07 RS25205
gene id: 93221:RO07_RS25205
uniprot id: A0A378Z7D6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09920
gene id: 93221:RO07_RS09920
uniprot id: A0A378YZQ8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23710
gene id: 93221:RO07_RS23710
uniprot id: A0A378Z6Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL24 family.
messages: One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
messages: One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS02085
gene id: 93221:RO07_RS02085
uniprot id: A0A378Z669
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS18315
gene id: 93221:RO07_RS18315
uniprot id: A0A378Z9C2
names: Similarity
messages: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.

93221:RO07 RS05875
gene id: 93221:RO07_RS05875
uniprot id: A0A378Z2S3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

93221:RO07 RS21050
gene id: 93221:RO07_RS21050
uniprot id: A0A378Z8L2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the thiolase-like superfamily. FabH family.
messages: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.
messages: Cytoplasm
messages: Homodimer.
messages: The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.

93221:RO07 RS11530
gene id: 93221:RO07_RS11530
uniprot id: A0A378YZP5
names: Function
names: Similarity
messages: Belongs to the LpxB family.
messages: Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

93221:RO07 RS09305
gene id: 93221:RO07_RS09305
uniprot id: A0A378Z031
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93221:RO07 RS15380
gene id: 93221:RO07_RS15380
uniprot id: A0A378ZAY5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06860
gene id: 93221:RO07_RS06860
uniprot id: A0A378Z1C6
names: Function
names: Similarity
messages: Belongs to the CobU/CobP family.
messages: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.

93221:RO07 RS04440
gene id: 93221:RO07_RS04440
uniprot id: A0A378Z2P5
names: Similarity
messages: Belongs to the MxiH/PrgI/YscF family.

93221:RO07 RS10550
gene id: 93221:RO07_RS10550
uniprot id: A0A378YZ43
names: Function
names: Similarity
messages: Belongs to the Dus family. DusA subfamily.
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs.

93221:RO07 RS02720
gene id: 93221:RO07_RS02720
uniprot id: A0A378Z3Q1
names: Cofactor
names: Function
names: Similarity
messages: Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
messages: Belongs to the Nth/MutY family.
messages: Binds 1 [4Fe-4S] cluster.

93221:RO07 RS09905
gene id: 93221:RO07_RS09905
uniprot id: A0A378Z146
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccD/PCCB family.
messages: Binds 1 zinc ion per subunit.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS09310
gene id: 93221:RO07_RS09310
uniprot id: A0A378Z0T5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UvrB family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.
messages: The beta-hairpin motif is involved in DNA binding.

93221:RO07 RS17140
gene id: 93221:RO07_RS17140
uniprot id: A0A378ZAT1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01785
gene id: 93221:RO07_RS01785
uniprot id: A0A378Z6C9
names: Similarity
messages: Belongs to the iron/ascorbate-dependent oxidoreductase family.

93221:RO07 RS05455
gene id: 93221:RO07_RS05455
uniprot id: A0A378Z2Z0
names: Similarity
messages: Belongs to the RuBisCO large chain family.

93221:RO07 RS04220
gene id: 93221:RO07_RS04220
uniprot id: A0A378Z4R0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS06395
gene id: 93221:RO07_RS06395
uniprot id: A0A378Z3I1
names: Function
names: Miscellaneous
names: Similarity
messages: Belongs to the L-aspartate dehydrogenase family.
messages: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
messages: The iminoaspartate product is unstable in aqueous solution and can decompose to oxaloacetate and ammonia.

93221:RO07 RS22795
gene id: 93221:RO07_RS22795
uniprot id: A0A378Z6U7
names: Function
names: Similarity
messages: Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
messages: Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.

93221:RO07 RS03490
gene id: 93221:RO07_RS03490
uniprot id: A0A378Z421
names: Cofactor
names: Similarity
messages: Belongs to the 4HPPD family.
messages: Binds 1 Fe cation per subunit.

93221:RO07 RS24930
gene id: 93221:RO07_RS24930
uniprot id: A0A378Z6U2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sigma-70 factor family. FliA subfamily.
messages: Cytoplasm
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes.

93221:RO07 RS14160
gene id: 93221:RO07_RS14160
uniprot id: A0A378ZCQ0
names: Function
names: Similarity
names: Subunit
messages: Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
messages: Homodimer.
messages: In the C-terminal section; belongs to the MurCDEF family.

93221:RO07 RS01835
gene id: 93221:RO07_RS01835
uniprot id: A0A378Z6C1
names: Subcellular Location Annotation
messages: Periplasm

93221:RO07 RS02335
gene id: 93221:RO07_RS02335
uniprot id: A0A378Z414
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS14600
gene id: 93221:RO07_RS14600
uniprot id: A0A378ZD15
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methylthiotransferase family. RimO subfamily.
messages: Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.
messages: Cytoplasm

93221:RO07 RS02905
gene id: 93221:RO07_RS02905
uniprot id: A0A378Z5H6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20905
gene id: 93221:RO07_RS20905
uniprot id: A0A378Z7T9
names: Function
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.
messages: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.

93221:RO07 RS02395
gene id: 93221:RO07_RS02395
uniprot id: A0A378Z5J0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS03010
gene id: 93221:RO07_RS03010
uniprot id: A0A378Z4X9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05960
gene id: 93221:RO07_RS05960
uniprot id: A0A378Z1V4
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

93221:RO07 RS09635
gene id: 93221:RO07_RS09635
uniprot id: A0A378Z1J5
names: Function
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.

93221:RO07 RS09880
gene id: 93221:RO07_RS09880
uniprot id: A0A378YZG7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tRNA pseudouridine synthase TruA family.
messages: Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS15340
gene id: 93221:RO07_RS15340
uniprot id: A0A378ZD20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

93221:RO07 RS19750
gene id: 93221:RO07_RS19750
uniprot id: A0A378Z8J3
names: Similarity
messages: In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.
messages: In the N-terminal section; belongs to the malic enzymes family.

93221:RO07 RS15725
gene id: 93221:RO07_RS15725
uniprot id: A0A378ZAR6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06520
gene id: 93221:RO07_RS06520
uniprot id: A0A378Z1I0
names: Similarity
messages: Belongs to the PAPS reductase family. CysD subfamily.

93221:RO07 RS11885
gene id: 93221:RO07_RS11885
uniprot id: A0A378Z046
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-III family.

93221:RO07 RS19915
gene id: 93221:RO07_RS19915
uniprot id: A0A378ZAD6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the quinolinate synthase family. Type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
messages: Cytoplasm

93221:RO07 RS04315
gene id: 93221:RO07_RS04315
uniprot id: A0A378Z4X7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily.
messages: Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS09435
gene id: 93221:RO07_RS09435
uniprot id: A0A378Z0W0
names: Similarity
messages: Belongs to the RecJ family.

93221:RO07 RS24870
gene id: 93221:RO07_RS24870
uniprot id: A0A378Z6H6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
messages: Bacterial flagellum basal body
messages: Belongs to the FlgH family.
messages: Cell outer membrane
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod.

93221:RO07 RS04810
gene id: 93221:RO07_RS04810
uniprot id: A0A378Z2F6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MotA family.
messages: Membrane

93221:RO07 RS00290
gene id: 93221:RO07_RS00290
uniprot id: A0A378Z607
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

93221:RO07 RS01425
gene id: 93221:RO07_RS01425
uniprot id: A0A378Z6B9
names: Cofactor
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: A single active site specifically recognizes both ATP and CTP and is responsible for their addition.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. Bacterial CCA-adding enzyme type 1 subfamily.
messages: Catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases.
messages: Comprises two domains: an N-terminal domain containing the nucleotidyltransferase activity and a C-terminal HD domain associated with both phosphodiesterase and phosphatase activities.
messages: Magnesium is required for nucleotidyltransferase activity.
messages: Monomer. Can also form homodimers and oligomers.
messages: Nickel for phosphatase activity.

93221:RO07 RS21160
gene id: 93221:RO07_RS21160
uniprot id: A0A378Z7P8
names: Function
messages: Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.

93221:RO07 RS01465
gene id: 93221:RO07_RS01465
uniprot id: A0A378Z6H7
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.
messages: Cytoplasm
messages: Homotrimer.
messages: In the C-terminal section; belongs to the transferase hexapeptide repeat family.
messages: In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS16330
gene id: 93221:RO07_RS16330
uniprot id: A0A378ZBG1
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

93221:RO07 RS25260
gene id: 93221:RO07_RS25260
uniprot id: A0A378Z6X0
names: Similarity
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.

93221:RO07 RS08255
gene id: 93221:RO07_RS08255
uniprot id: A0A378Z2B9
names: Function
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

93221:RO07 RS18655
gene id: 93221:RO07_RS18655
uniprot id: A0A378ZAX2
names: Caution
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS06190
gene id: 93221:RO07_RS06190
uniprot id: A0A378Z3I7
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.
messages: In the C-terminal section; belongs to the GTP cyclohydrolase II family.
messages: In the N-terminal section; belongs to the DHBP synthase family.

93221:RO07 RS13860
gene id: 93221:RO07_RS13860
uniprot id: A0A378ZBR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

93221:RO07 RS15730
gene id: 93221:RO07_RS15730
uniprot id: A0A378ZAR9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23690
gene id: 93221:RO07_RS23690
uniprot id: A0A378Z7H1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL6 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.

93221:RO07 RS20325
gene id: 93221:RO07_RS20325
uniprot id: A0A378Z9N5
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DnaJ family.
messages: Binds 2 Zn(2+) ions per monomer.
messages: Cytoplasm
messages: Homodimer.
messages: Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.
messages: The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.

93221:RO07 RS19740
gene id: 93221:RO07_RS19740
uniprot id: A0A378Z8I3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS09725
gene id: 93221:RO07_RS09725
uniprot id: A0A378YZJ4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS17620
gene id: 93221:RO07_RS17620
uniprot id: A0A378Z9R5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS11745
gene id: 93221:RO07_RS11745
uniprot id: A0A0A8BRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

93221:RO07 RS17130
gene id: 93221:RO07_RS17130
uniprot id: A0A378ZBI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Slam family.
messages: Cell outer membrane
messages: Membrane

93221:RO07 RS06685
gene id: 93221:RO07_RS06685
uniprot id: A0A378Z1D6
names: Function
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS1 family.
messages: Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.

93221:RO07 RS06800
gene id: 93221:RO07_RS06800
uniprot id: A0A378Z365
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Cob(I)alamin adenosyltransferase family.
messages: Cytoplasm
messages: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.

93221:RO07 RS13615
gene id: 93221:RO07_RS13615
uniprot id: A0A378ZBZ1
names: Function
names: Subcellular Location Annotation
messages: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS11605
gene id: 93221:RO07_RS11605
uniprot id: A0A378YYJ8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS20355
gene id: 93221:RO07_RS20355
uniprot id: A0A378Z872
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Cytoplasm

93221:RO07 RS22910
gene id: 93221:RO07_RS22910
uniprot id: A0A378Z8J2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS02420
gene id: 93221:RO07_RS02420
uniprot id: A0A378Z3Y0
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS18950
gene id: 93221:RO07_RS18950
uniprot id: A0A378Z9R0
names: Function
names: Subunit
messages: Catalyzes the transfer of an acetyl group from acetyl-CoA to the 6'-amino group of aminoglycoside molecules conferring resistance to antibiotics containing the purpurosamine ring.
messages: Homodimer.

93221:RO07 RS19980
gene id: 93221:RO07_RS19980
uniprot id: A0A378Z965
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ClpS family.
messages: Binds to the N-terminal domain of the chaperone ClpA.
messages: Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.

93221:RO07 RS13030
gene id: 93221:RO07_RS13030
uniprot id: A0A379LPD7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04680
gene id: 93221:RO07_RS04680
uniprot id: A0A378Z402
names: Function
names: Similarity
messages: Belongs to the aspartate/glutamate racemases family.
messages: Provides the (R)-glutamate required for cell wall biosynthesis.

93221:RO07 RS22295
gene id: 93221:RO07_RS22295
uniprot id: A0A378Z7X4
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

93221:RO07 RS20150
gene id: 93221:RO07_RS20150
uniprot id: A0A378Z891
names: Function
names: Similarity
messages: Belongs to the nucleoside phosphorylase PpnP family.
messages: Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.

93221:RO07 RS23920
gene id: 93221:RO07_RS23920
uniprot id: A0A378Z848
names: Function
names: Similarity
messages: Belongs to the NusG family.
messages: Participates in transcription elongation, termination and antitermination.

93221:RO07 RS18725
gene id: 93221:RO07_RS18725
uniprot id: A0A378Z936
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21445
gene id: 93221:RO07_RS21445
uniprot id: A0A378Z917
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0187 family.
messages: Membrane

93221:RO07 RS15165
gene id: 93221:RO07_RS15165
uniprot id: A0A378ZD49
names: Similarity
messages: Belongs to the 3-oxoacid CoA-transferase subunit B family.

93221:RO07 RS14790
gene id: 93221:RO07_RS14790
uniprot id: A0A378ZDB6
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

93221:RO07 RS13035
gene id: 93221:RO07_RS13035
uniprot id: A0A379LPB9
names: Similarity
names: Subunit
messages: Belongs to the NAD(P)-dependent epimerase/dehydratase family.
messages: Homodimer.

93221:RO07 RS19955
gene id: 93221:RO07_RS19955
uniprot id: A0A378Z951
names: Caution
names: Cofactor
names: Function
names: Similarity
messages: Binds 1 FMN per subunit.
messages: Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.
messages: In the C-terminal section; belongs to the PPC synthetase family.
messages: In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS18905
gene id: 93221:RO07_RS18905
uniprot id: A0A378ZA34
names: Similarity
messages: Belongs to the lysine N(6)-hydroxylase/L-ornithine N(5)-oxygenase family.

93221:RO07 RS04880
gene id: 93221:RO07_RS04880
uniprot id: A0A378Z3F9
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS22510
gene id: 93221:RO07_RS22510
uniprot id: A0A378Z6Y1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RsmH family.
messages: Cytoplasm
messages: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.

93221:RO07 RS04030
gene id: 93221:RO07_RS04030
uniprot id: A0A378Z4C2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00270
gene id: 93221:RO07_RS00270
uniprot id: A0A378Z565
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS08190
gene id: 93221:RO07_RS08190
uniprot id: A0A378Z1F0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13380
gene id: 93221:RO07_RS13380
uniprot id: A0A378ZC56
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS01070
gene id: 93221:RO07_RS01070
uniprot id: A0A378Z6P8
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS16935
gene id: 93221:RO07_RS16935
uniprot id: A0A378ZAW4
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.
messages: Belongs to the AAA ATPase family.
messages: Binds 1 zinc ion per subunit.
messages: Cell membrane
messages: Homohexamer.
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the central section; belongs to the AAA ATPase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS07955
gene id: 93221:RO07_RS07955
uniprot id: A0A378Z2T2
names: Similarity
messages: Belongs to the ETF beta-subunit/FixA family.

93221:RO07 RS16990
gene id: 93221:RO07_RS16990
uniprot id: A0A0A8BRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ureidoglycolate lyase family.
messages: Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source.
messages: Homodimer.

93221:RO07 RS12040
gene id: 93221:RO07_RS12040
uniprot id: A0A378YZA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS21045
gene id: 93221:RO07_RS21045
uniprot id: A0A378Z9L4
names: Similarity
messages: Belongs to the fabD family.

93221:RO07 RS10005
gene id: 93221:RO07_RS10005
uniprot id: A0A378Z134
names: Similarity
messages: Belongs to the GST superfamily.

93221:RO07 RS02040
gene id: 93221:RO07_RS02040
uniprot id: A0A378Z5Q9
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

93221:RO07 RS20105
gene id: 93221:RO07_RS20105
uniprot id: A0A378Z8C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
messages: Belongs to the KdsB family.
messages: Cytoplasm

93221:RO07 RS19560
gene id: 93221:RO07_RS19560
uniprot id: A0A378ZAM3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon.

93221:RO07 RS18605
gene id: 93221:RO07_RS18605
uniprot id: A0A378ZAY3
names: Similarity
messages: Belongs to the peptidase S13 family.

93221:RO07 RS06335
gene id: 93221:RO07_RS06335
uniprot id: A0A378Z3T1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial glucokinase family.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the bacterial glucokinase family.

93221:RO07 RS09890
gene id: 93221:RO07_RS09890
uniprot id: A0A378Z1E9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the TrpB family.
messages: Tetramer of two alpha and two beta chains.
messages: The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.

93221:RO07 RS10480
gene id: 93221:RO07_RS10480
uniprot id: A0A378YZ60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the L/F-transferase family.
messages: Cytoplasm
messages: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.

93221:RO07 RS08845
gene id: 93221:RO07_RS08845
uniprot id: A0A378Z234
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00800
gene id: 93221:RO07_RS00800
uniprot id: A0A378Z4U8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MreD family.
messages: Membrane

93221:RO07 RS08360
gene id: 93221:RO07_RS08360
uniprot id: A0A378Z0D2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the formate dehydrogenase gamma subunit family.
messages: Membrane

93221:RO07 RS22410
gene id: 93221:RO07_RS22410
uniprot id: A0A378Z700
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA gyrase inhibitor YacG family.
messages: Binds 1 zinc ion.
messages: Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
messages: Interacts with GyrB.

93221:RO07 RS14250
gene id: 93221:RO07_RS14250
uniprot id: A0A378ZD81
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06175
gene id: 93221:RO07_RS06175
uniprot id: A0A378Z2L4
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS23160
gene id: 93221:RO07_RS23160
uniprot id: A0A378Z830
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS22090
gene id: 93221:RO07_RS22090
uniprot id: A0A378Z907
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

93221:RO07 RS08265
gene id: 93221:RO07_RS08265
uniprot id: A0A378Z2E4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

93221:RO07 RS24785
gene id: 93221:RO07_RS24785
uniprot id: A0A378Z5M4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliF family.
messages: Membrane
messages: The M ring may be actively involved in energy transduction.

93221:RO07 RS16290
gene id: 93221:RO07_RS16290
uniprot id: A0A378ZAG5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DNA polymerase type-A family.
messages: In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
messages: Single-chain monomer with multiple functions.

93221:RO07 RS10430
gene id: 93221:RO07_RS10430
uniprot id: A0A378YZ76
names: Similarity
messages: Belongs to the peptidase S11 family.

93221:RO07 RS12875
gene id: 93221:RO07_RS12875
uniprot id: A0A379LP87
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS02615
gene id: 93221:RO07_RS02615
uniprot id: A0A378Z3T4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sigma-70 factor family. RpoH subfamily.
messages: Cytoplasm
messages: Interacts with the RNA polymerase core enzyme.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.

93221:RO07 RS21970
gene id: 93221:RO07_RS21970
uniprot id: A0A378Z814
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.
messages: Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.
messages: Cell membrane
messages: Membrane

93221:RO07 RS16340
gene id: 93221:RO07_RS16340
uniprot id: A0A378ZAF6
names: Similarity
messages: Belongs to the UDPGP type 2 family.

93221:RO07 RS15530
gene id: 93221:RO07_RS15530
uniprot id: A0A378ZBQ1
names: Function
names: Similarity
messages: Belongs to the relA/spoT family.
messages: In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.

93221:RO07 RS21985
gene id: 93221:RO07_RS21985
uniprot id: A0A378Z8R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the gmhB family.
messages: Cytoplasm

93221:RO07 RS22405
gene id: 93221:RO07_RS22405
uniprot id: A0A378Z6Z8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ZapD family.
messages: Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
messages: Cytoplasm
messages: Interacts with FtsZ.

93221:RO07 RS03030
gene id: 93221:RO07_RS03030
uniprot id: A0A378Z4B6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23815
gene id: 93221:RO07_RS23815
uniprot id: A0A378Z675
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10460
gene id: 93221:RO07_RS10460
uniprot id: A0A378Z170
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

93221:RO07 RS00405
gene id: 93221:RO07_RS00405
uniprot id: A0A378Z528
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10060
gene id: 93221:RO07_RS10060
uniprot id: A0A378YZD9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).
messages: Belongs to the AccA family.
messages: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
messages: Cytoplasm

93221:RO07 RS18980
gene id: 93221:RO07_RS18980
uniprot id: A0A378ZA24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
messages: Belongs to the SrkA/RdoA protein kinase family.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS19425
gene id: 93221:RO07_RS19425
uniprot id: A0A378Z9I0
names: Activity Regulation
names: Cofactor
names: Function
names: Similarity
messages: Allosterically activated by GTP.
messages: Belongs to the UPRTase family.
messages: Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.
messages: Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.

93221:RO07 RS10925
gene id: 93221:RO07_RS10925
uniprot id: A0A378Z0U5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.
messages: Belongs to the RNR ribonuclease family. RNase R subfamily.
messages: Cytoplasm

93221:RO07 RS20670
gene id: 93221:RO07_RS20670
uniprot id: A0A378Z818
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS08675
gene id: 93221:RO07_RS08675
uniprot id: A0A378Z073
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TolB family.
messages: Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
messages: Periplasm
messages: The Tol-Pal system is composed of five core proteins: the inner membrane proteins TolA, TolQ and TolR, the periplasmic protein TolB and the outer membrane protein Pal. They form a network linking the inner and outer membranes and the peptidoglycan layer.

93221:RO07 RS03185
gene id: 93221:RO07_RS03185
uniprot id: A0A378Z3E1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

93221:RO07 RS05765
gene id: 93221:RO07_RS05765
uniprot id: A0A378Z1W5
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

93221:RO07 RS09825
gene id: 93221:RO07_RS09825
uniprot id: A0A378Z0J6
names: Cofactor
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Membrane
messages: Membrane-anchoring subunit of succinate dehydrogenase (SDH).
messages: Part of an enzyme complex containing four subunits: a flavoprotein, an iron-sulfur protein, plus two membrane-anchoring proteins, SdhC and SdhD.
messages: The heme is bound between the two transmembrane subunits.

93221:RO07 RS04225
gene id: 93221:RO07_RS04225
uniprot id: A0A378Z3R7
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: Catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

93221:RO07 RS11410
gene id: 93221:RO07_RS11410
uniprot id: A0A378YYN3
names: Similarity
messages: Belongs to the ArsC family.

93221:RO07 RS00420
gene id: 93221:RO07_RS00420
uniprot id: A0A378Z722
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22580
gene id: 93221:RO07_RS22580
uniprot id: A0A378Z6W9
names: Similarity
messages: Belongs to the bacterial solute-binding protein 3 family.

93221:RO07 RS04295
gene id: 93221:RO07_RS04295
uniprot id: A0A378Z2Q9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS01320
gene id: 93221:RO07_RS01320
uniprot id: A0A378Z6K3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS08015
gene id: 93221:RO07_RS08015
uniprot id: A0A378Z2J8
names: Similarity
messages: Belongs to the YggT family.

93221:RO07 RS24515
gene id: 93221:RO07_RS24515
uniprot id: A0A378Z7S1
names: Function
names: Similarity
messages: In the C-terminal section; belongs to the aldehyde dehydrogenase family.
messages: In the N-terminal section; belongs to the proline dehydrogenase family.
messages: Oxidizes proline to glutamate for use as a carbon and nitrogen source.

93221:RO07 RS02670
gene id: 93221:RO07_RS02670
uniprot id: A0A378Z3Q7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the bacterial CoaD family.
messages: Cytoplasm
messages: Homohexamer.
messages: Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.

93221:RO07 RS09220
gene id: 93221:RO07_RS09220
uniprot id: A0A378YZU7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the heat shock protein 90 family.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Molecular chaperone. Has ATPase activity.

93221:RO07 RS25060
gene id: 93221:RO07_RS25060
uniprot id: A0A378Z5H7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has four main subunits: a(1), b(1), b'(1) and c(9-12).
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.

93221:RO07 RS20495
gene id: 93221:RO07_RS20495
uniprot id: A0A378Z972
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS20735
gene id: 93221:RO07_RS20735
uniprot id: A0A378Z9S2
names: Similarity
messages: Belongs to the mandelate racemase/muconate lactonizing enzyme family. GlucD subfamily.

93221:RO07 RS21980
gene id: 93221:RO07_RS21980
uniprot id: A0A378Z994
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93221:RO07 RS14465
gene id: 93221:RO07_RS14465
uniprot id: A0A378ZBF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS08665
gene id: 93221:RO07_RS08665
uniprot id: A0A378Z1V6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CpoB family.
messages: Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division.
messages: Periplasm

93221:RO07 RS22455
gene id: 93221:RO07_RS22455
uniprot id: A0A378Z6Y8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsQ/DivIB family. FtsQ subfamily.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

93221:RO07 RS13005
gene id: 93221:RO07_RS13005
uniprot id: A0A379LRT7
names: Similarity
messages: Belongs to the NodU/CmcH family.

93221:RO07 RS06600
gene id: 93221:RO07_RS06600
uniprot id: A0A378Z3E7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter small permease family.
messages: Cell inner membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

93221:RO07 RS05770
gene id: 93221:RO07_RS05770
uniprot id: A0A378Z232
names: Similarity
messages: Belongs to the intradiol ring-cleavage dioxygenase family.

93221:RO07 RS02735
gene id: 93221:RO07_RS02735
uniprot id: A0A378Z4I1
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the HPrK/P family.
messages: Both phosphorylation and phosphorolysis are carried out by the same active site and suggest a common mechanism for both reactions.
messages: Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
messages: Homohexamer.
messages: The Walker A ATP-binding motif also binds Pi and PPi.

93221:RO07 RS04165
gene id: 93221:RO07_RS04165
uniprot id: A0A378Z4J0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn).
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS02425
gene id: 93221:RO07_RS02425
uniprot id: A0A378Z3X8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PEP-utilizing enzyme family.
messages: Cytoplasm
messages: General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).

93221:RO07 RS26380
gene id: 93221:RO07_RS26380
uniprot id: A0A378ZAD5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Cytochrome bo(3) ubiquinol terminal oxidase is the component of the aerobic respiratory chain of E.coli that predominates when cells are grown at high aeration. Has proton pump activity across the membrane in addition to electron transfer, pumping 2 protons/electron.
messages: Heterooctamer of two A chains, two B chains, two C chains and two D chains.
messages: Membrane

93221:RO07 RS11150
gene id: 93221:RO07_RS11150
uniprot id: A0A378YYU5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PriB family.
messages: Binds single-stranded DNA at the primosome assembly site (PAS).
messages: Component of the preprimosomal complex composed of PriA, PriB, PriC, DnaB and DnaT. Upon transient interaction with DnaG it forms the primosome.

93221:RO07 RS21820
gene id: 93221:RO07_RS21820
uniprot id: A0A378Z843
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS08685
gene id: 93221:RO07_RS08685
uniprot id: A0A378Z160
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

93221:RO07 RS14795
gene id: 93221:RO07_RS14795
uniprot id: A0A378ZCR4
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).

93221:RO07 RS17800
gene id: 93221:RO07_RS17800
uniprot id: A0A378Z9L0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.
messages: Membrane

93221:RO07 RS01360
gene id: 93221:RO07_RS01360
uniprot id: A0A378Z5A7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15905
gene id: 93221:RO07_RS15905
uniprot id: A0A378ZCC0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22225
gene id: 93221:RO07_RS22225
uniprot id: A0A378Z778
names: Function
names: Similarity
messages: Belongs to the MurCDEF family. Mpl subfamily.
messages: Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl-meso-diaminopimelate by linking it to UDP-N-acetylmuramate.

93221:RO07 RS04125
gene id: 93221:RO07_RS04125
uniprot id: A0A378Z3S9
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).

93221:RO07 RS12110
gene id: 93221:RO07_RS12110
uniprot id: A0A378Z0C2
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS17045
gene id: 93221:RO07_RS17045
uniprot id: A0A378ZA14
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS21465
gene id: 93221:RO07_RS21465
uniprot id: A0A378Z7I9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS02775
gene id: 93221:RO07_RS02775
uniprot id: A0A378Z3N8
names: Similarity
messages: Belongs to the SIS family. GutQ/KpsF subfamily.

93221:RO07 RS02555
gene id: 93221:RO07_RS02555
uniprot id: A0A378Z570
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 3 family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23320
gene id: 93221:RO07_RS23320
uniprot id: A0A378Z8H4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Periplasm

93221:RO07 RS10370
gene id: 93221:RO07_RS10370
uniprot id: A0A378Z0W8
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

93221:RO07 RS23300
gene id: 93221:RO07_RS23300
uniprot id: A0A378Z6I2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome b family.
messages: Binds 2 heme groups non-covalently.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

93221:RO07 RS03840
gene id: 93221:RO07_RS03840
uniprot id: A0A378Z558
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

93221:RO07 RS23910
gene id: 93221:RO07_RS23910
uniprot id: A0A378Z6V6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL1 family.
messages: Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
messages: Part of the 50S ribosomal subunit.
messages: Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.

93221:RO07 RS17090
gene id: 93221:RO07_RS17090
uniprot id: A0A378ZB16
names: Similarity
messages: Belongs to the transglycosylase Slt family.

93221:RO07 RS07300
gene id: 93221:RO07_RS07300
uniprot id: A0A378Z137
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS13845
gene id: 93221:RO07_RS13845
uniprot id: A0A378ZCJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0073 (Hly-III) family.
messages: Membrane

93221:RO07 RS23000
gene id: 93221:RO07_RS23000
uniprot id: A0A378Z8N3
names: Similarity
messages: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.

93221:RO07 RS23410
gene id: 93221:RO07_RS23410
uniprot id: A0A378Z761
names: Similarity
messages: Belongs to the BolA/IbaG family.

93221:RO07 RS15330
gene id: 93221:RO07_RS15330
uniprot id: A0A378ZBU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

93221:RO07 RS13895
gene id: 93221:RO07_RS13895
uniprot id: A0A378ZCI7
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. TatD-type hydrolase family.

93221:RO07 RS09630
gene id: 93221:RO07_RS09630
uniprot id: A0A378Z1U0
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

93221:RO07 RS01805
gene id: 93221:RO07_RS01805
uniprot id: A0A378Z5M0
names: Similarity
messages: Belongs to the SIMIBI class G3E GTPase family. ZNG1 subfamily.

93221:RO07 RS11525
gene id: 93221:RO07_RS11525
uniprot id: A0A378Z0N3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the transferase hexapeptide repeat family. LpxA subfamily.
messages: Cytoplasm
messages: Homotrimer.
messages: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.

93221:RO07 RS22425
gene id: 93221:RO07_RS22425
uniprot id: A0A378Z733
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate.
messages: Cytoplasm
messages: Heterotetramer of two alpha and two beta chains.
messages: Some bacteria possess a monofunctional ArgJ, i.e., capable of catalyzing only the fifth step of the arginine biosynthetic pathway.

93221:RO07 RS08110
gene id: 93221:RO07_RS08110
uniprot id: A0A378Z2F8
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93221:RO07 RS24945
gene id: 93221:RO07_RS24945
uniprot id: A0A378Z5J7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell membrane
messages: Membrane
messages: Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.

93221:RO07 RS11960
gene id: 93221:RO07_RS11960
uniprot id: A0A378Z092
names: Similarity
messages: Belongs to the complex I 51 kDa subunit family.

93221:RO07 RS06330
gene id: 93221:RO07_RS06330
uniprot id: A0A378Z1K6
names: Function
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
messages: Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

93221:RO07 RS11725
gene id: 93221:RO07_RS11725
uniprot id: A0A378Z0E1
names: Similarity
messages: Belongs to the peptidase S66 family.

93221:RO07 RS22060
gene id: 93221:RO07_RS22060
uniprot id: A0A378Z766
names: Similarity
messages: Belongs to the transcriptional regulatory Fis family.

93221:RO07 RS21315
gene id: 93221:RO07_RS21315
uniprot id: A0A378Z8G1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS02655
gene id: 93221:RO07_RS02655
uniprot id: A0A378Z4N1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC-2 integral membrane protein family. Lipooligosaccharide exporter (TC 3.A.1.102) subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
messages: The complex is composed of two ATP-binding proteins (NodI) and two transmembrane proteins (NodJ).

93221:RO07 RS21385
gene id: 93221:RO07_RS21385
uniprot id: A0A378Z8C7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22395
gene id: 93221:RO07_RS22395
uniprot id: A0A378Z7W9
names: Similarity
messages: Belongs to the peptidase A24 family.

93221:RO07 RS11360
gene id: 93221:RO07_RS11360
uniprot id: A0A378YYP1
names: Similarity
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.

93221:RO07 RS15115
gene id: 93221:RO07_RS15115
uniprot id: A0A378ZCK1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
messages: Binds 2 magnesium ions per tetramer.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93221:RO07 RS18520
gene id: 93221:RO07_RS18520
uniprot id: A0A378Z967
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS11245
gene id: 93221:RO07_RS11245
uniprot id: A0A378YYS3
names: Similarity
messages: Belongs to the threonine synthase family.

93221:RO07 RS16300
gene id: 93221:RO07_RS16300
uniprot id: A0A378ZBA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0394 family.
messages: Membrane

93221:RO07 RS07010
gene id: 93221:RO07_RS07010
uniprot id: A0A378Z262
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24795
gene id: 93221:RO07_RS24795
uniprot id: A0A378Z6C4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

93221:RO07 RS09645
gene id: 93221:RO07_RS09645
uniprot id: A0A378Z0S0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 1 family.
messages: Cell membrane
messages: Membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone.

93221:RO07 RS04140
gene id: 93221:RO07_RS04140
uniprot id: A0A378Z2U1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC1 family. UbiB subfamily.
messages: Cell membrane
messages: Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS17645
gene id: 93221:RO07_RS17645
uniprot id: A0A378ZAS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.
messages: Cell membrane

93221:RO07 RS23700
gene id: 93221:RO07_RS23700
uniprot id: A0A378Z693
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS14 family.
messages: Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.
messages: Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.

93221:RO07 RS24150
gene id: 93221:RO07_RS24150
uniprot id: A0A378Z614
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS24780
gene id: 93221:RO07_RS24780
uniprot id: A0A378Z5M3
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliE family.

93221:RO07 RS00530
gene id: 93221:RO07_RS00530
uniprot id: A0A378Z6U0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS17285
gene id: 93221:RO07_RS17285
uniprot id: A0A378ZBF6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAMP family.
messages: Cell membrane
messages: H(+)-stimulated, divalent metal cation uptake system.

93221:RO07 RS19510
gene id: 93221:RO07_RS19510
uniprot id: A0A378ZAN4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.
messages: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.
messages: Homodimer.

93221:RO07 RS06855
gene id: 93221:RO07_RS06855
uniprot id: A0A378Z2W9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CobD/CbiB family.
messages: Cell membrane
messages: Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS13320
gene id: 93221:RO07_RS13320
uniprot id: A0A378ZC51
names: Similarity
messages: Belongs to the OsmC/Ohr family.

93221:RO07 RS07020
gene id: 93221:RO07_RS07020
uniprot id: A0A378Z3E5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS15160
gene id: 93221:RO07_RS15160
uniprot id: A0A378ZB35
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS17385
gene id: 93221:RO07_RS17385
uniprot id: A0A378ZBE0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.

93221:RO07 RS03500
gene id: 93221:RO07_RS03500
uniprot id: A0A378Z5C9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
messages: Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
messages: Homotetramer.

93221:RO07 RS24905
gene id: 93221:RO07_RS24905
uniprot id: A0A378Z7J3
names: Subcellular Location Annotation
messages: Periplasm

93221:RO07 RS10305
gene id: 93221:RO07_RS10305
uniprot id: A0A378Z164
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS23660
gene id: 93221:RO07_RS23660
uniprot id: A0A378Z712
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IF-1 family.
messages: Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.
messages: Cytoplasm
messages: One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.

93221:RO07 RS19635
gene id: 93221:RO07_RS19635
uniprot id: A0A378Z9N0
names: Function
names: Similarity
names: Subunit
messages: A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild-type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity.
messages: Belongs to the RecC family.
messages: Heterotrimer of RecB, RecC and RecD. All subunits contribute to DNA-binding.

93221:RO07 RS08575
gene id: 93221:RO07_RS08575
uniprot id: A0A378Z180
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS03635
gene id: 93221:RO07_RS03635
uniprot id: A0A378Z3Z3
names: Similarity
messages: Belongs to the GMC oxidoreductase family.

93221:RO07 RS13270
gene id: 93221:RO07_RS13270
uniprot id: A0A378ZC42
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-dependent hydrolases superfamily. HutI family.
messages: Binds 1 zinc or iron ion per subunit.
messages: Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.
messages: Cytoplasm

93221:RO07 RS24730
gene id: 93221:RO07_RS24730
uniprot id: A0A378Z5N4
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS12740
gene id: 93221:RO07_RS12740
uniprot id: A0A379LP75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

93221:RO07 RS04305
gene id: 93221:RO07_RS04305
uniprot id: A0A378Z3L9
names: Function
names: Similarity
messages: Belongs to the anhydro-N-acetylmuramic acid kinase family.
messages: Catalyzes the specific phosphorylation of 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling.

93221:RO07 RS02640
gene id: 93221:RO07_RS02640
uniprot id: A0A378Z5V4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. FtsY subfamily.
messages: Cell membrane
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Membrane
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

93221:RO07 RS08095
gene id: 93221:RO07_RS08095
uniprot id: A0A378Z1H2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal stress protein A family.
messages: Cytoplasm

93221:RO07 RS02055
gene id: 93221:RO07_RS02055
uniprot id: A0A378Z5H4
names: Similarity
messages: Belongs to the thioesterase PaaI family.

93221:RO07 RS04430
gene id: 93221:RO07_RS04430
uniprot id: A0A378Z3P6
names: Similarity
messages: Belongs to the glutamate synthase family.

93221:RO07 RS22360
gene id: 93221:RO07_RS22360
uniprot id: A0A378Z724
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL27 family.

93221:RO07 RS25095
gene id: 93221:RO07_RS25095
uniprot id: A0A378Z5G1
names: Function
names: Similarity
messages: Belongs to the ParB family.
messages: Involved in chromosome partition. Localize to both poles of the predivisional cell following completion of DNA replication. Binds to the DNA origin of replication.

93221:RO07 RS20445
gene id: 93221:RO07_RS20445
uniprot id: A0A378Z840
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.

93221:RO07 RS18100
gene id: 93221:RO07_RS18100
uniprot id: A0A378ZAI2
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS19890
gene id: 93221:RO07_RS19890
uniprot id: A0A378Z8E9
names: Similarity
messages: Belongs to the UPF0758 family.

93221:RO07 RS06765
gene id: 93221:RO07_RS06765
uniprot id: A0A378Z1E8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS06355
gene id: 93221:RO07_RS06355
uniprot id: A0A378Z358
names: Similarity
messages: Belongs to the heat shock protein 70 family.

93221:RO07 RS17040
gene id: 93221:RO07_RS17040
uniprot id: A0A378ZB26
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05800
gene id: 93221:RO07_RS05800
uniprot id: A0A378Z2Y2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24875
gene id: 93221:RO07_RS24875
uniprot id: A0A378Z6U9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.
messages: The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.

93221:RO07 RS12260
gene id: 93221:RO07_RS12260
uniprot id: A0A378YZB1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09365
gene id: 93221:RO07_RS09365
uniprot id: A0A378Z1Z1
names: Similarity
messages: Belongs to the adrenodoxin/putidaredoxin family.

93221:RO07 RS06660
gene id: 93221:RO07_RS06660
uniprot id: A0A378Z305
names: Function
names: Subcellular Location Annotation
messages: Catalyzes the Claisen rearrangement of chorismate to prephenate and the decarboxylation/dehydration of prephenate to phenylpyruvate.
messages: Cytoplasm

93221:RO07 RS11345
gene id: 93221:RO07_RS11345
uniprot id: A0A378YYQ3
names: Similarity
messages: Belongs to the DEAD box helicase family.

93221:RO07 RS13105
gene id: 93221:RO07_RS13105
uniprot id: A0A379LQX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial solute-binding protein SsuA/TauA family.
messages: Periplasm

93221:RO07 RS00815
gene id: 93221:RO07_RS00815
uniprot id: A0A378Z4V9
names: Function
names: Similarity
names: Subunit
messages: Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).
messages: Belongs to the GatC family.
messages: Heterotrimer of A, B and C subunits.

93221:RO07 RS15195
gene id: 93221:RO07_RS15195
uniprot id: A0A378ZB14
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

93221:RO07 RS20275
gene id: 93221:RO07_RS20275
uniprot id: A0A378Z9P1
names: Function
names: Similarity
messages: Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control.
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

93221:RO07 RS25145
gene id: 93221:RO07_RS25145
uniprot id: A0A378Z5F7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS17915
gene id: 93221:RO07_RS17915
uniprot id: A0A378Z9K5
names: Similarity
messages: Belongs to the IlvD/Edd family.

93221:RO07 RS19950
gene id: 93221:RO07_RS19950
uniprot id: A0A378Z8F2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A8 family.
messages: Cell membrane
messages: This protein specifically catalyzes the removal of signal peptides from prolipoproteins.

93221:RO07 RS10015
gene id: 93221:RO07_RS10015
uniprot id: A0A378YZF1
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.

93221:RO07 RS25285
gene id: 93221:RO07_RS25285
uniprot id: A0A378Z5B9
names: Similarity
messages: Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.

93221:RO07 RS15860
gene id: 93221:RO07_RS15860
uniprot id: A0A378ZBI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS11260
gene id: 93221:RO07_RS11260
uniprot id: A0A378YYQ8
names: Similarity
names: Subunit
messages: Belongs to the MoaE family.
messages: Heterotetramer of 2 MoaD subunits and 2 MoaE subunits. Also stable as homodimer. The enzyme changes between these two forms during catalysis.

93221:RO07 RS11355
gene id: 93221:RO07_RS11355
uniprot id: A0A378YZP4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acetylates the N-terminal alanine of ribosomal protein S18.
messages: Belongs to the acetyltransferase family. RimI subfamily.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS02100
gene id: 93221:RO07_RS02100
uniprot id: A0A378Z501
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS10340
gene id: 93221:RO07_RS10340
uniprot id: A0A378Z0A0
names: Function
names: Similarity
messages: Belongs to the band 7/mec-2 family. HflC subfamily.
messages: HflC and HflK could regulate a protease.

93221:RO07 RS11785
gene id: 93221:RO07_RS11785
uniprot id: A0A378YZK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
messages: Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
messages: Homotetramer.

93221:RO07 RS24985
gene id: 93221:RO07_RS24985
uniprot id: A0A378Z5I4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

93221:RO07 RS04135
gene id: 93221:RO07_RS04135
uniprot id: A0A378Z2U9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiJ family.
messages: Cytoplasm
messages: Required for ubiquinone (coenzyme Q) biosynthesis. Binds hydrophobic ubiquinone biosynthetic intermediates via its SCP2 domain and is essential for the stability of the Ubi complex. May constitute a docking platform where Ubi enzymes assemble and access their SCP2-bound polyprenyl substrates.

93221:RO07 RS11405
gene id: 93221:RO07_RS11405
uniprot id: A0A378YZM5
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase M20A family. DapE subfamily.
messages: Binds 2 Zn(2+) or Co(2+) ions per subunit.
messages: Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
messages: Homodimer.

93221:RO07 RS23790
gene id: 93221:RO07_RS23790
uniprot id: A0A378Z7E8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS12 family.
messages: Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
messages: Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.
messages: With S4 and S5 plays an important role in translational accuracy.

93221:RO07 RS19305
gene id: 93221:RO07_RS19305
uniprot id: A0A378Z8U0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS24815
gene id: 93221:RO07_RS24815
uniprot id: A0A378Z7F8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliL family.
messages: Cell inner membrane
messages: Controls the rotational direction of flagella during chemotaxis.
messages: Membrane

93221:RO07 RS19340
gene id: 93221:RO07_RS19340
uniprot id: A0A378Z8R5
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS02090
gene id: 93221:RO07_RS02090
uniprot id: A0A378Z5Q1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioredoxin family. DsbA subfamily.
messages: Periplasm

93221:RO07 RS22050
gene id: 93221:RO07_RS22050
uniprot id: A0A378Z8C4
names: Similarity
messages: Belongs to the UbiH/COQ6 family.

93221:RO07 RS18685
gene id: 93221:RO07_RS18685
uniprot id: A0A378Z9V9
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

93221:RO07 RS20100
gene id: 93221:RO07_RS20100
uniprot id: A0A378Z8A2
names: Similarity
messages: Belongs to the UPF0434 family.

93221:RO07 RS22065
gene id: 93221:RO07_RS22065
uniprot id: A0A378Z773
names: Domain
names: Similarity
messages: Belongs to the PurH family.
messages: The IMP cyclohydrolase activity resides in the N-terminal region.

93221:RO07 RS15135
gene id: 93221:RO07_RS15135
uniprot id: A0A378ZB24
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS19905
gene id: 93221:RO07_RS19905
uniprot id: A0A378Z961
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily.
messages: Catalyzes the oxidation of L-aspartate to iminoaspartate.
messages: Cytoplasm

93221:RO07 RS11520
gene id: 93221:RO07_RS11520
uniprot id: A0A378Z0H4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the thioester dehydratase family. FabZ subfamily.
messages: Cytoplasm
messages: Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.

93221:RO07 RS14140
gene id: 93221:RO07_RS14140
uniprot id: A0A378ZDQ3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04615
gene id: 93221:RO07_RS04615
uniprot id: A0A378Z4A2
names: Similarity
messages: Belongs to the catalase family.

93221:RO07 RS20500
gene id: 93221:RO07_RS20500
uniprot id: A0A378Z829
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS06300
gene id: 93221:RO07_RS06300
uniprot id: A0A378Z2N2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily.
messages: Cell inner membrane
messages: Mediates magnesium influx to the cytosol.

93221:RO07 RS23675
gene id: 93221:RO07_RS23675
uniprot id: A0A378Z7S7
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL30 family.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS10990
gene id: 93221:RO07_RS10990
uniprot id: A0A378Z0L5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04625
gene id: 93221:RO07_RS04625
uniprot id: A0A378Z3K7
names: Similarity
messages: Belongs to the Dps family.

93221:RO07 RS09705
gene id: 93221:RO07_RS09705
uniprot id: A0A378YZL2
names: Similarity
messages: Belongs to the GST superfamily.

93221:RO07 RS20050
gene id: 93221:RO07_RS20050
uniprot id: A0A378Z8B1
names: Similarity
messages: Belongs to the pseudouridine synthase RsuA family.

93221:RO07 RS11090
gene id: 93221:RO07_RS11090
uniprot id: A0A378Z0J3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the peptidase S24 family.
messages: Homodimer.
messages: Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.

93221:RO07 RS16125
gene id: 93221:RO07_RS16125
uniprot id: A0A378ZAK5
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

93221:RO07 RS18450
gene id: 93221:RO07_RS18450
uniprot id: A0A378ZAR7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Homodimer.

93221:RO07 RS20455
gene id: 93221:RO07_RS20455
uniprot id: A0A378Z847
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
messages: Cell inner membrane

93221:RO07 RS00765
gene id: 93221:RO07_RS00765
uniprot id: A0A378Z4W9
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.
messages: Binds 1 S-adenosyl-L-methionine per subunit.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
messages: Homodimer.

93221:RO07 RS07340
gene id: 93221:RO07_RS07340
uniprot id: A0A378Z242
names: Similarity
messages: Belongs to the ABC transporter superfamily.

93221:RO07 RS24440
gene id: 93221:RO07_RS24440
uniprot id: A0A378Z5U6
names: Function
names: Similarity
messages: Belongs to the RlpA family.
messages: Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.

93221:RO07 RS03175
gene id: 93221:RO07_RS03175
uniprot id: A0A378Z3G0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS10325
gene id: 93221:RO07_RS10325
uniprot id: A0A378YZ87
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Hfq family.
messages: Homohexamer.
messages: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs.

93221:RO07 RS24140
gene id: 93221:RO07_RS24140
uniprot id: A0A378Z606
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09070
gene id: 93221:RO07_RS09070
uniprot id: A0A378YZY5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS13600
gene id: 93221:RO07_RS13600
uniprot id: A0A378ZCP4
names: Similarity
messages: Belongs to the universal stress protein A family.

93221:RO07 RS20960
gene id: 93221:RO07_RS20960
uniprot id: A0A378Z7T8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the elongation factor P family.
messages: Cytoplasm
messages: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.

93221:RO07 RS02435
gene id: 93221:RO07_RS02435
uniprot id: A0A378Z3Y4
names: Similarity
messages: Belongs to the peptidase S41A family.

93221:RO07 RS09530
gene id: 93221:RO07_RS09530
uniprot id: A0A378Z1P4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Catalyzes the attachment of tryptophan to tRNA(Trp).
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS00805
gene id: 93221:RO07_RS00805
uniprot id: A0A378Z4U4
names: Function
names: Similarity
messages: Belongs to the MreC family.
messages: Involved in formation and maintenance of cell shape.

93221:RO07 RS18290
gene id: 93221:RO07_RS18290
uniprot id: A0A378ZAU8
names: Similarity
messages: Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.

93221:RO07 RS13290
gene id: 93221:RO07_RS13290
uniprot id: A0A378ZE74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS08370
gene id: 93221:RO07_RS08370
uniprot id: A0A378Z299
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SelA family.
messages: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
messages: Cytoplasm

93221:RO07 RS04955
gene id: 93221:RO07_RS04955
uniprot id: A0A378Z384
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the flagella basal body rod proteins family.

93221:RO07 RS06760
gene id: 93221:RO07_RS06760
uniprot id: A0A378Z2Y7
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

93221:RO07 RS02440
gene id: 93221:RO07_RS02440
uniprot id: A0A378Z5Z6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.
messages: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.
messages: Homodimer.

93221:RO07 RS12345
gene id: 93221:RO07_RS12345
uniprot id: A0A378Z019
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

93221:RO07 RS22505
gene id: 93221:RO07_RS22505
uniprot id: A0A378Z6X9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsL family.
messages: Cell inner membrane
messages: Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
messages: Membrane
messages: Part of a complex composed of FtsB, FtsL and FtsQ.

93221:RO07 RS23730
gene id: 93221:RO07_RS23730
uniprot id: A0A378Z817
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL16 family.
messages: Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS24470
gene id: 93221:RO07_RS24470
uniprot id: A0A378Z7C8
names: Similarity
messages: Belongs to the hyi family.

93221:RO07 RS00015
gene id: 93221:RO07_RS00015
uniprot id: A0A378Z6U3
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the type II topoisomerase GyrB family.
messages: Belongs to the type II topoisomerase family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

93221:RO07 RS07060
gene id: 93221:RO07_RS07060
uniprot id: A0A378Z252
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PPase family.
messages: Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
messages: Cytoplasm
messages: Homohexamer.

93221:RO07 RS15520
gene id: 93221:RO07_RS15520
uniprot id: A0A378ZAV6
names: Similarity
messages: Belongs to the pirin family.

93221:RO07 RS11325
gene id: 93221:RO07_RS11325
uniprot id: A0A378Z0R3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS09445
gene id: 93221:RO07_RS09445
uniprot id: A0A378YZR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

93221:RO07 RS22775
gene id: 93221:RO07_RS22775
uniprot id: A0A378Z6S7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

93221:RO07 RS20260
gene id: 93221:RO07_RS20260
uniprot id: A0A378Z8Y6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIR synthase family.
messages: Cytoplasm

93221:RO07 RS22250
gene id: 93221:RO07_RS22250
uniprot id: A0A378Z888
names: Function
names: Subunit
messages: Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.
messages: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.

93221:RO07 RS02225
gene id: 93221:RO07_RS02225
uniprot id: A0A378Z4U1
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A monovalent cation. Ammonium or potassium.
messages: Belongs to the type III pantothenate kinase family.
messages: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS03855
gene id: 93221:RO07_RS03855
uniprot id: A0A378Z3X6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS04690
gene id: 93221:RO07_RS04690
uniprot id: A0A378Z2H7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-I fumarase family.
messages: Catalyzes the reversible hydration of fumarate to (S)-malate.
messages: Homodimer.

93221:RO07 RS11185
gene id: 93221:RO07_RS11185
uniprot id: A0A378Z0H5
names: Similarity
messages: Belongs to the PhoH family.

93221:RO07 RS02995
gene id: 93221:RO07_RS02995
uniprot id: A0A378Z564
names: Caution
names: Function
names: Subunit
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.

93221:RO07 RS22785
gene id: 93221:RO07_RS22785
uniprot id: A0A378Z6T4
names: Domain
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the glutamyl-tRNA reductase family.
messages: Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
messages: During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.
messages: Homodimer.
messages: Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.

93221:RO07 RS18465
gene id: 93221:RO07_RS18465
uniprot id: A0A378ZAB7
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS11100
gene id: 93221:RO07_RS11100
uniprot id: A0A378YYV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import.
messages: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane.
messages: The complex is composed of two ATP-binding proteins (CysA), two transmembrane proteins (CysT and CysW) and a solute-binding protein (CysP).

93221:RO07 RS23565
gene id: 93221:RO07_RS23565
uniprot id: A0A378Z8B8
names: Similarity
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: In the C-terminal section; belongs to the transpeptidase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 51 family.
messages: Membrane

93221:RO07 RS23755
gene id: 93221:RO07_RS23755
uniprot id: A0A378Z688
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL23 family.
messages: One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
messages: Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.

93221:RO07 RS11650
gene id: 93221:RO07_RS11650
uniprot id: A0A378YYS2
names: Function
names: Similarity
messages: Belongs to the ketopantoate reductase family.
messages: Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.

93221:RO07 RS16520
gene id: 93221:RO07_RS16520
uniprot id: A0A378ZCG0
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the maleate isomerase family.
messages: Catalyzes cis-trans isomerization of the C2-C3 double bond in maleate to yield fumarate.
messages: Homodimer.
messages: Reaction is initiated by nucleophilic attack of cysteine at the double bond, yielding a covalent succinylcysteine-like intermediate.

93221:RO07 RS02075
gene id: 93221:RO07_RS02075
uniprot id: A0A378Z4X8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS12085
gene id: 93221:RO07_RS12085
uniprot id: A0A378YYI7
names: Function
names: Similarity
messages: Belongs to the FtsK/SpoIIIE/SftA family.
messages: Essential cell division protein that coordinates cell division and chromosome segregation. The N-terminus is involved in assembly of the cell-division machinery. The C-terminus functions as a DNA motor that moves dsDNA in an ATP-dependent manner towards the dif recombination site, which is located within the replication terminus region. Translocation stops specifically at Xer-dif sites, where FtsK interacts with the Xer recombinase, allowing activation of chromosome unlinking by recombination. FtsK orienting polar sequences (KOPS) guide the direction of DNA translocation. FtsK can remove proteins from DNA as it translocates, but translocation stops specifically at XerCD-dif site, thereby preventing removal of XerC and XerD from dif.

93221:RO07 RS08445
gene id: 93221:RO07_RS08445
uniprot id: A0A378Z2B2
names: Similarity
names: Subunit
messages: Belongs to the threonine aldolase family.
messages: Homotetramer.

93221:RO07 RS02585
gene id: 93221:RO07_RS02585
uniprot id: A0A378Z5W4
names: Similarity
messages: Belongs to the SCO1/2 family.

93221:RO07 RS18305
gene id: 93221:RO07_RS18305
uniprot id: A0A378ZAE6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06740
gene id: 93221:RO07_RS06740
uniprot id: A0A378Z3K0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS11845
gene id: 93221:RO07_RS11845
uniprot id: A0A378YYF7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phospholipase A1 family.
messages: Binds 1 Ca(2+) ion per monomer. In the dimeric form the Ca(2+) is bound by different amino acids with binding of each Ca(2+) shared with ligands coming from each monomer. The Ca(2+) ion may have a role in catalysis.
messages: Cell outer membrane
messages: Homodimer; dimerization is reversible, and the dimeric form is the active one.
messages: Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities.
messages: Membrane

93221:RO07 RS03400
gene id: 93221:RO07_RS03400
uniprot id: A0A378Z5F2
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

93221:RO07 RS21175
gene id: 93221:RO07_RS21175
uniprot id: A0A378Z7P0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS08125
gene id: 93221:RO07_RS08125
uniprot id: A0A378Z261
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAE transporter (TC 2.A.81) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS03950
gene id: 93221:RO07_RS03950
uniprot id: A0A378Z2Y8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS03100
gene id: 93221:RO07_RS03100
uniprot id: A0A378Z5D4
names: Function
names: Similarity
messages: Acts on leucine, isoleucine and valine.
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS15360
gene id: 93221:RO07_RS15360
uniprot id: A0A378ZC11
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

93221:RO07 RS19085
gene id: 93221:RO07_RS19085
uniprot id: A0A378Z8V9
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

93221:RO07 RS08725
gene id: 93221:RO07_RS08725
uniprot id: A0A378Z067
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS17865
gene id: 93221:RO07_RS17865
uniprot id: A0A378Z9L8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS07360
gene id: 93221:RO07_RS07360
uniprot id: A0A378Z182
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS19515
gene id: 93221:RO07_RS19515
uniprot id: A0A378ZA51
names: Function
names: Similarity
messages: Belongs to the glucose-1-phosphate thymidylyltransferase family.
messages: Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.

93221:RO07 RS13280
gene id: 93221:RO07_RS13280
uniprot id: A0A378ZC57
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22490
gene id: 93221:RO07_RS22490
uniprot id: A0A378Z8S4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family. MurF subfamily.
messages: Cytoplasm
messages: Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.

93221:RO07 RS24020
gene id: 93221:RO07_RS24020
uniprot id: A0A378Z7L1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS06725
gene id: 93221:RO07_RS06725
uniprot id: A0A378Z1K3
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

93221:RO07 RS09665
gene id: 93221:RO07_RS09665
uniprot id: A0A378YZV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the complex I subunit 5 family.
messages: Membrane

93221:RO07 RS03625
gene id: 93221:RO07_RS03625
uniprot id: A0A378Z363
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS25215
gene id: 93221:RO07_RS25215
uniprot id: A0A378Z775
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

93221:RO07 RS23365
gene id: 93221:RO07_RS23365
uniprot id: A0A378Z6I1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

93221:RO07 RS02700
gene id: 93221:RO07_RS02700
uniprot id: A0A378Z5C4
names: Function
names: Similarity
messages: Belongs to the GHMP kinase family. IspE subfamily.
messages: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol.

93221:RO07 RS06605
gene id: 93221:RO07_RS06605
uniprot id: A0A378Z2I2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAP transporter large permease family.
messages: Cell inner membrane
messages: Membrane
messages: Part of the tripartite ATP-independent periplasmic (TRAP) transport system.
messages: The complex comprises the extracytoplasmic solute receptor protein and the two transmembrane proteins.

93221:RO07 RS19310
gene id: 93221:RO07_RS19310
uniprot id: A0A378ZAS4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS02630
gene id: 93221:RO07_RS02630
uniprot id: A0A378Z4K1
names: Similarity
messages: Belongs to the GST superfamily. Zeta family.

93221:RO07 RS08355
gene id: 93221:RO07_RS08355
uniprot id: A0A378Z1B8
names: Cofactor
messages: Binds 4 [4Fe-4S] clusters per subunit.

93221:RO07 RS10525
gene id: 93221:RO07_RS10525
uniprot id: A0A378Z086
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

93221:RO07 RS04200
gene id: 93221:RO07_RS04200
uniprot id: A0A378Z3P0
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS04215
gene id: 93221:RO07_RS04215
uniprot id: A0A378Z4H9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04985
gene id: 93221:RO07_RS04985
uniprot id: A0A378Z3V0
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the flagella basal body rod proteins family.
messages: Secreted

93221:RO07 RS12805
gene id: 93221:RO07_RS12805
uniprot id: A0A379LRH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS16325
gene id: 93221:RO07_RS16325
uniprot id: A0A378ZB90
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05995
gene id: 93221:RO07_RS05995
uniprot id: A0A378Z3Q8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

93221:RO07 RS05900
gene id: 93221:RO07_RS05900
uniprot id: A0A378Z2W3
names: Similarity
messages: Belongs to the MotB family.

93221:RO07 RS07045
gene id: 93221:RO07_RS07045
uniprot id: A0A378Z192
names: Similarity
messages: Belongs to the DapA family.

93221:RO07 RS16845
gene id: 93221:RO07_RS16845
uniprot id: A0A378ZA58
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS00835
gene id: 93221:RO07_RS00835
uniprot id: A0A378Z5P6
names: Similarity
messages: Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.

93221:RO07 RS02450
gene id: 93221:RO07_RS02450
uniprot id: A0A378Z5S4
names: Function
names: Similarity
messages: Belongs to the glutaredoxin family.
messages: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.

93221:RO07 RS22780
gene id: 93221:RO07_RS22780
uniprot id: A0A378Z6T2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0410 family.
messages: Membrane

93221:RO07 RS11570
gene id: 93221:RO07_RS11570
uniprot id: A0A378Z0G4
names: Similarity
messages: Belongs to the ribosome association toxin RatA family.

93221:RO07 RS20985
gene id: 93221:RO07_RS20985
uniprot id: A0A378Z9T0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.
messages: Cell membrane
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS16075
gene id: 93221:RO07_RS16075
uniprot id: A0A378ZBE2
names: Similarity
messages: Belongs to the cytochrome P450 family.

93221:RO07 RS16255
gene id: 93221:RO07_RS16255
uniprot id: A0A378ZAI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XseB family.
messages: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.
messages: Cytoplasm
messages: Heterooligomer composed of large and small subunits.

93221:RO07 RS11335
gene id: 93221:RO07_RS11335
uniprot id: A0A378Z0E3
names: Similarity
messages: Belongs to the malate synthase family.

93221:RO07 RS21810
gene id: 93221:RO07_RS21810
uniprot id: A0A378Z7C1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.
messages: Membrane

93221:RO07 RS04405
gene id: 93221:RO07_RS04405
uniprot id: A0A378Z2P0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PNT beta subunit family.
messages: Cell inner membrane
messages: Membrane
messages: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.

93221:RO07 RS06200
gene id: 93221:RO07_RS06200
uniprot id: A0A378Z2Q0
names: Similarity
messages: Belongs to the AHA1 family.

93221:RO07 RS11430
gene id: 93221:RO07_RS11430
uniprot id: A0A378YZR8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SMC family.
messages: Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.
messages: Cytoplasm
messages: Homodimer.
messages: Required for chromosome condensation and partitioning.

93221:RO07 RS15940
gene id: 93221:RO07_RS15940
uniprot id: A0A378ZAN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS22630
gene id: 93221:RO07_RS22630
uniprot id: A0A378Z6W4
names: Function
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
messages: Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.

93221:RO07 RS04705
gene id: 93221:RO07_RS04705
uniprot id: A0A378Z2H6
names: Caution
names: Function
names: PTM
names: Similarity
messages: Acetylated. Deacetylation by the SIR2-homolog deacetylase activates the enzyme.
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS11830
gene id: 93221:RO07_RS11830
uniprot id: A0A378YZJ5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS12225
gene id: 93221:RO07_RS12225
uniprot id: A0A378YY85
names: Similarity
messages: Belongs to the HipA Ser/Thr kinase family.

93221:RO07 RS04715
gene id: 93221:RO07_RS04715
uniprot id: A0A378Z488
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

93221:RO07 RS21890
gene id: 93221:RO07_RS21890
uniprot id: A0A378Z945
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS11175
gene id: 93221:RO07_RS11175
uniprot id: A0A378Z0P8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20090
gene id: 93221:RO07_RS20090
uniprot id: A0A378Z9E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

93221:RO07 RS09855
gene id: 93221:RO07_RS09855
uniprot id: A0A378Z157
names: Similarity
messages: Belongs to the EcnA/EcnB lipoprotein family.

93221:RO07 RS16510
gene id: 93221:RO07_RS16510
uniprot id: A0A378ZB63
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15455
gene id: 93221:RO07_RS15455
uniprot id: A0A378ZCL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS11550
gene id: 93221:RO07_RS11550
uniprot id: A0A378YYT7
names: Function
names: Similarity
messages: Belongs to the PEP-utilizing enzyme family.
messages: Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.

93221:RO07 RS21850
gene id: 93221:RO07_RS21850
uniprot id: A0A378Z7B0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS25335
gene id: 93221:RO07_RS25335
uniprot id: A0A378Z5A9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS14590
gene id: 93221:RO07_RS14590
uniprot id: A0A378ZDF7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS17705
gene id: 93221:RO07_RS17705
uniprot id: A0A378Z9P6
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the NrdR family.
messages: Binds 1 zinc ion.
messages: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.

93221:RO07 RS04895
gene id: 93221:RO07_RS04895
uniprot id: A0A378Z2D3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliS family.
messages: cytosol

93221:RO07 RS22330
gene id: 93221:RO07_RS22330
uniprot id: A0A378Z922
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

93221:RO07 RS08270
gene id: 93221:RO07_RS08270
uniprot id: A0A378Z1I1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS03485
gene id: 93221:RO07_RS03485
uniprot id: A0A378Z399
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06670
gene id: 93221:RO07_RS06670
uniprot id: A0A378Z1E2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EPSP synthase family.
messages: Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.

93221:RO07 RS00650
gene id: 93221:RO07_RS00650
uniprot id: A0A378Z4X2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphoenolpyruvate carboxykinase [GTP] family.
messages: Binds 1 Mn(2+) ion per subunit.
messages: Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS22695
gene id: 93221:RO07_RS22695
uniprot id: A0A378Z6W7
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17920
gene id: 93221:RO07_RS17920
uniprot id: A0A378ZBM6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01240
gene id: 93221:RO07_RS01240
uniprot id: A0A378Z5X2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10930
gene id: 93221:RO07_RS10930
uniprot id: A0A378Z0Z2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. RlmB subfamily.
messages: Cytoplasm
messages: Specifically methylates the ribose of guanosine 2251 in 23S rRNA.

93221:RO07 RS15655
gene id: 93221:RO07_RS15655
uniprot id: A0A378ZCA8
names: Cofactor
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.

93221:RO07 RS03205
gene id: 93221:RO07_RS03205
uniprot id: A0A378Z4B8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RuvA family.
messages: Forms a complex with RuvB.
messages: The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

93221:RO07 RS09410
gene id: 93221:RO07_RS09410
uniprot id: A0A378YZQ6
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS09345
gene id: 93221:RO07_RS09345
uniprot id: A0A378Z022
names: Similarity
messages: Belongs to the HesB/IscA family.

93221:RO07 RS08970
gene id: 93221:RO07_RS08970
uniprot id: A0A378Z104
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase TrmD family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates guanosine-37 in various tRNAs.

93221:RO07 RS05905
gene id: 93221:RO07_RS05905
uniprot id: A0A378Z3E4
names: Function
names: Similarity
messages: Belongs to the FlgM family.
messages: Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA.

93221:RO07 RS17735
gene id: 93221:RO07_RS17735
uniprot id: A0A378ZBF8
names: Similarity
messages: Belongs to the peptidase C56 family.

93221:RO07 RS24835
gene id: 93221:RO07_RS24835
uniprot id: A0A378Z5L4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

93221:RO07 RS20085
gene id: 93221:RO07_RS20085
uniprot id: A0A378Z947
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exbB/tolQ family.
messages: Membrane

93221:RO07 RS14050
gene id: 93221:RO07_RS14050
uniprot id: A0A378ZDC2
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

93221:RO07 RS26790
gene id: 93221:RO07_RS26790
uniprot id: A0A378Z5I2
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

93221:RO07 RS25315
gene id: 93221:RO07_RS25315
uniprot id: A0A378Z753
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Catalyzes the last two steps in the biosynthesis of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the DAO family.
messages: In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family.

93221:RO07 RS15425
gene id: 93221:RO07_RS15425
uniprot id: A0A378ZAX9
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

93221:RO07 RS23780
gene id: 93221:RO07_RS23780
uniprot id: A0A378Z808
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Cytoplasm

93221:RO07 RS01545
gene id: 93221:RO07_RS01545
uniprot id: A0A378Z4E9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 87 family.
messages: Membrane

93221:RO07 RS10955
gene id: 93221:RO07_RS10955
uniprot id: A0A378YZ59
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ArgA subfamily.
messages: Cytoplasm
messages: In bacteria which possess the bifunctional enzyme ornithine acetyltransferase/N-acetylglutamate synthase (ArgJ), ArgA fulfills an anaplerotic role.

93221:RO07 RS17080
gene id: 93221:RO07_RS17080
uniprot id: A0A378ZBQ9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS20955
gene id: 93221:RO07_RS20955
uniprot id: A0A378Z8Y2
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 104 family.
messages: Protein-arginine rhamnosyltransferase that catalyzes the transfer of a single rhamnose to elongation factor P (EF-P) on 'Lys-32', a modification required for EF-P-dependent rescue of polyproline stalled ribosomes.

93221:RO07 RS13885
gene id: 93221:RO07_RS13885
uniprot id: A0A378ZDB4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS23745
gene id: 93221:RO07_RS23745
uniprot id: A0A378Z676
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.
messages: Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.

93221:RO07 RS21060
gene id: 93221:RO07_RS21060
uniprot id: A0A378Z7R8
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

93221:RO07 RS01110
gene id: 93221:RO07_RS01110
uniprot id: A0A378Z5F0
names: Similarity
messages: Belongs to the leucine-binding protein family.

93221:RO07 RS09225
gene id: 93221:RO07_RS09225
uniprot id: A0A378Z1S4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiC family.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway.

93221:RO07 RS06875
gene id: 93221:RO07_RS06875
uniprot id: A0A378Z290
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PanD family.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
messages: Cytoplasm
messages: Heterooctamer of four alpha and four beta subunits.
messages: Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.

93221:RO07 RS25115
gene id: 93221:RO07_RS25115
uniprot id: A0A378Z7F4
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MnmG family.
messages: Cytoplasm
messages: Homodimer. Heterotetramer of two MnmE and two MnmG subunits.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.

93221:RO07 RS19405
gene id: 93221:RO07_RS19405
uniprot id: A0A378Z8S0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS01075
gene id: 93221:RO07_RS01075
uniprot id: A0A378Z694
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS18810
gene id: 93221:RO07_RS18810
uniprot id: A0A378Z914
names: Function
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.
messages: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.

93221:RO07 RS07255
gene id: 93221:RO07_RS07255
uniprot id: A0A378Z126
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS02945
gene id: 93221:RO07_RS02945
uniprot id: A0A378Z5P4
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS21155
gene id: 93221:RO07_RS21155
uniprot id: A0A378Z8T7
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

93221:RO07 RS14185
gene id: 93221:RO07_RS14185
uniprot id: A0A378ZBN8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00695
gene id: 93221:RO07_RS00695
uniprot id: A0A378Z4W1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS03745
gene id: 93221:RO07_RS03745
uniprot id: A0A378Z4R6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS18400
gene id: 93221:RO07_RS18400
uniprot id: A0A378ZAT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS20220
gene id: 93221:RO07_RS20220
uniprot id: A0A378ZA78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS16240
gene id: 93221:RO07_RS16240
uniprot id: A0A378ZAH7
names: Function
names: Similarity
messages: Belongs to the GTP cyclohydrolase IV family.
messages: Converts GTP to 7,8-dihydroneopterin triphosphate.

93221:RO07 RS07415
gene id: 93221:RO07_RS07415
uniprot id: A0A378Z1X9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane

93221:RO07 RS15815
gene id: 93221:RO07_RS15815
uniprot id: A0A378ZBS0
names: Similarity
messages: Belongs to the thioesterase family.

93221:RO07 RS05070
gene id: 93221:RO07_RS05070
uniprot id: A0A378Z2B7
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS24600
gene id: 93221:RO07_RS24600
uniprot id: A0A378Z5R8
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS24805
gene id: 93221:RO07_RS24805
uniprot id: A0A378Z7L5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliJ family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS25050
gene id: 93221:RO07_RS25050
uniprot id: A0A378Z5H8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Cell membrane
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.

93221:RO07 RS08295
gene id: 93221:RO07_RS08295
uniprot id: A0A378Z1D0
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS23830
gene id: 93221:RO07_RS23830
uniprot id: A0A378Z7Z3
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10605
gene id: 93221:RO07_RS10605
uniprot id: A0A378Z105
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PurK/PurT family.
messages: Homodimer.
messages: Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate.

93221:RO07 RS19815
gene id: 93221:RO07_RS19815
uniprot id: A0A378ZAF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily.
messages: Membrane

93221:RO07 RS11475
gene id: 93221:RO07_RS11475
uniprot id: A0A378Z0P1
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UMP kinase family.
messages: Catalyzes the reversible phosphorylation of UMP to UDP.
messages: Cytoplasm
messages: Homohexamer.
messages: Inhibited by UTP.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22200
gene id: 93221:RO07_RS22200
uniprot id: A0A378Z897
names: Function
names: Similarity
names: Subunit
messages: Belongs to the shikimate dehydrogenase family.
messages: Homodimer.
messages: Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).

93221:RO07 RS19105
gene id: 93221:RO07_RS19105
uniprot id: A0A378Z8X8
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS10080
gene id: 93221:RO07_RS10080
uniprot id: A0A378Z0E6
names: Similarity
messages: Belongs to the aspartokinase family.

93221:RO07 RS15610
gene id: 93221:RO07_RS15610
uniprot id: A0A378ZCI6
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21205
gene id: 93221:RO07_RS21205
uniprot id: A0A378Z9I3
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

93221:RO07 RS25075
gene id: 93221:RO07_RS25075
uniprot id: A0A378Z7A2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase C chain family.
messages: Cell membrane
messages: F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.
messages: Membrane

93221:RO07 RS00910
gene id: 93221:RO07_RS00910
uniprot id: A0A378Z4U0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase A24 family.
messages: Cell inner membrane
messages: Cell membrane
messages: Membrane
messages: Plays an essential role in type IV pili and type II pseudopili formation by proteolytically removing the leader sequence from substrate proteins and subsequently monomethylating the alpha-amino group of the newly exposed N-terminal phenylalanine.

93221:RO07 RS23310
gene id: 93221:RO07_RS23310
uniprot id: A0A378Z781
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MscL family.
messages: Cell inner membrane
messages: Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
messages: Homopentamer.
messages: Membrane

93221:RO07 RS11740
gene id: 93221:RO07_RS11740
uniprot id: A0A378Z070
names: Similarity
messages: Belongs to the allantoicase family.

93221:RO07 RS23635
gene id: 93221:RO07_RS23635
uniprot id: A0A378Z770
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the RNA polymerase alpha chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.
messages: The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.

93221:RO07 RS11715
gene id: 93221:RO07_RS11715
uniprot id: A0A378YYI4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04875
gene id: 93221:RO07_RS04875
uniprot id: A0A378Z4C7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliH family.
messages: Cytoplasm
messages: Needed for flagellar regrowth and assembly.

93221:RO07 RS09860
gene id: 93221:RO07_RS09860
uniprot id: A0A378YZI2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LeuD family. LeuD type 1 subfamily.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93221:RO07 RS22355
gene id: 93221:RO07_RS22355
uniprot id: A0A378Z705
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS23650
gene id: 93221:RO07_RS23650
uniprot id: A0A378Z6A3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS13 family.
messages: Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.
messages: Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.

93221:RO07 RS22465
gene id: 93221:RO07_RS22465
uniprot id: A0A378Z703
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurCDEF family.
messages: Cell wall formation.
messages: Cytoplasm

93221:RO07 RS22645
gene id: 93221:RO07_RS22645
uniprot id: A0A378Z6Y6
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the anthranilate phosphoribosyltransferase family.
messages: Binds 2 magnesium ions per monomer.
messages: Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22180
gene id: 93221:RO07_RS22180
uniprot id: A0A378Z954
names: Similarity
messages: Belongs to the OMP decarboxylase family. Type 2 subfamily.

93221:RO07 RS00555
gene id: 93221:RO07_RS00555
uniprot id: A0A378Z4Z3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the peptidase M81 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC).

93221:RO07 RS13570
gene id: 93221:RO07_RS13570
uniprot id: A0A378ZBY8
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS02985
gene id: 93221:RO07_RS02985
uniprot id: A0A378Z3I4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ABC transporter superfamily. UvrA family.
messages: Cytoplasm
messages: Forms a heterotetramer with UvrB during the search for lesions.
messages: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

93221:RO07 RS22485
gene id: 93221:RO07_RS22485
uniprot id: A0A378Z8H3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family. MraY subfamily.
messages: Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.
messages: Cell membrane
messages: Membrane

93221:RO07 RS21255
gene id: 93221:RO07_RS21255
uniprot id: A0A378Z953
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10950
gene id: 93221:RO07_RS10950
uniprot id: A0A378YYY2
names: Function
names: Similarity
messages: Belongs to the Fe(2+)-trafficking protein family.
messages: Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and/or repair of Fe-S clusters in biosynthetic enzymes.

93221:RO07 RS21805
gene id: 93221:RO07_RS21805
uniprot id: A0A378Z7C0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS00105
gene id: 93221:RO07_RS00105
uniprot id: A0A378Z592
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS10285
gene id: 93221:RO07_RS10285
uniprot id: A0A378YZI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NDK family.
messages: Cytoplasm
messages: Homotetramer.
messages: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

93221:RO07 RS24830
gene id: 93221:RO07_RS24830
uniprot id: A0A378Z5L2
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliO/MopB family.
messages: Cell membrane

93221:RO07 RS10050
gene id: 93221:RO07_RS10050
uniprot id: A0A378Z0H6
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: Monomer.

93221:RO07 RS22540
gene id: 93221:RO07_RS22540
uniprot id: A0A378Z8R6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93221:RO07 RS05740
gene id: 93221:RO07_RS05740
uniprot id: A0A378Z3R6
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS09175
gene id: 93221:RO07_RS09175
uniprot id: A0A378Z228
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS16355
gene id: 93221:RO07_RS16355
uniprot id: A0A378ZAG4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS24185
gene id: 93221:RO07_RS24185
uniprot id: A0A378Z772
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS22760
gene id: 93221:RO07_RS22760
uniprot id: A0A378Z8M2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GtrA family.
messages: Membrane

93221:RO07 RS25055
gene id: 93221:RO07_RS25055
uniprot id: A0A378Z677
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: Cell membrane
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.

93221:RO07 RS25030
gene id: 93221:RO07_RS25030
uniprot id: A0A378Z6E3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Bcr/CmlA family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS19965
gene id: 93221:RO07_RS19965
uniprot id: A0A378ZAC6
names: Similarity
messages: To bacterial alkanal monooxygenase alpha and beta chains.

93221:RO07 RS06585
gene id: 93221:RO07_RS06585
uniprot id: A0A378Z1F4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Lgt family.
messages: Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.
messages: Cell membrane

93221:RO07 RS26780
gene id: 93221:RO07_RS26780
uniprot id: A0A378ZB84
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.
messages: Cell inner membrane

93221:RO07 RS01315
gene id: 93221:RO07_RS01315
uniprot id: A0A378Z4L6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS12950
gene id: 93221:RO07_RS12950
uniprot id: A0A379LRK5
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS13080
gene id: 93221:RO07_RS13080
uniprot id: A0A379LPD1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS06210
gene id: 93221:RO07_RS06210
uniprot id: A0A378Z1Q6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15410
gene id: 93221:RO07_RS15410
uniprot id: A0A378ZBR3
names: Similarity
messages: Belongs to the LOG family.

93221:RO07 RS11020
gene id: 93221:RO07_RS11020
uniprot id: A0A378Z127
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NusA family.
messages: Cytoplasm
messages: Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.
messages: Participates in both transcription termination and antitermination.

93221:RO07 RS20160
gene id: 93221:RO07_RS20160
uniprot id: A0A378Z910
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MurB family.
messages: Cell wall formation.
messages: Cytoplasm

93221:RO07 RS13810
gene id: 93221:RO07_RS13810
uniprot id: A0A378ZBV1
names: Caution
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
messages: Binds 1 pyridoxal phosphate per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May also have succinyldiaminopimelate aminotransferase activity, thus carrying out the corresponding step in lysine biosynthesis.

93221:RO07 RS23595
gene id: 93221:RO07_RS23595
uniprot id: A0A378Z6A5
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS26125
gene id: 93221:RO07_RS26125
uniprot id: A0A378Z9C9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS23785
gene id: 93221:RO07_RS23785
uniprot id: A0A378Z735
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS7 family.
messages: One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.
messages: Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.

93221:RO07 RS23305
gene id: 93221:RO07_RS23305
uniprot id: A0A378Z6I3
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
messages: Membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.
messages: The main subunits of complex b-c1 are: cytochrome b, cytochrome c1 and the Rieske protein.

93221:RO07 RS09850
gene id: 93221:RO07_RS09850
uniprot id: A0A378Z0M6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
messages: Heterodimer of LeuC and LeuD.

93221:RO07 RS21975
gene id: 93221:RO07_RS21975
uniprot id: A0A378Z7C5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Cytoplasm
messages: Tetramer of two alpha and two beta subunits.

93221:RO07 RS23605
gene id: 93221:RO07_RS23605
uniprot id: A0A378Z6C5
names: PTM
messages: Binds 2 heme c groups covalently per subunit.

93221:RO07 RS07950
gene id: 93221:RO07_RS07950
uniprot id: A0A378Z0L6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21120
gene id: 93221:RO07_RS21120
uniprot id: A0A378Z7R2
names: Function
names: Similarity
messages: Belongs to the MoeA family.
messages: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.

93221:RO07 RS13485
gene id: 93221:RO07_RS13485
uniprot id: A0A378ZE29
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DapA family.
messages: Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.
messages: Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.

93221:RO07 RS08005
gene id: 93221:RO07_RS08005
uniprot id: A0A378Z2S2
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

93221:RO07 RS05645
gene id: 93221:RO07_RS05645
uniprot id: A0A378Z3X9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15760
gene id: 93221:RO07_RS15760
uniprot id: A0A378ZBJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
messages: Membrane

93221:RO07 RS02035
gene id: 93221:RO07_RS02035
uniprot id: A0A378Z679
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

93221:RO07 RS03480
gene id: 93221:RO07_RS03480
uniprot id: A0A378Z392
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

93221:RO07 RS22445
gene id: 93221:RO07_RS22445
uniprot id: A0A378Z7W2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FtsZ family.
messages: Cytoplasm
messages: Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
messages: Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.

93221:RO07 RS21210
gene id: 93221:RO07_RS21210
uniprot id: A0A378Z8I0
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS11135
gene id: 93221:RO07_RS11135
uniprot id: A0A378YZX2
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS18220
gene id: 93221:RO07_RS18220
uniprot id: A0A378ZA56
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17210
gene id: 93221:RO07_RS17210
uniprot id: A0A378Z9Z1
names: Similarity
messages: Belongs to the DEAD box helicase family.

93221:RO07 RS12725
gene id: 93221:RO07_RS12725
uniprot id: A0A379LP58
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: 4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.
messages: Cytoplasm

93221:RO07 RS14695
gene id: 93221:RO07_RS14695
uniprot id: A0A378ZCT4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00955
gene id: 93221:RO07_RS00955
uniprot id: A0A378Z4R1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit.
messages: Binds 2 divalent ions per subunit.
messages: Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
messages: Cytoplasm
messages: Homotetramer; dimer of dimers.

93221:RO07 RS07100
gene id: 93221:RO07_RS07100
uniprot id: A0A378Z158
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

93221:RO07 RS22320
gene id: 93221:RO07_RS22320
uniprot id: A0A378Z7T3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.
messages: Cytoplasm
messages: Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components.
messages: Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY. SRP is a ribonucleoprotein composed of Ffh and a 4.5S RNA molecule.

93221:RO07 RS06580
gene id: 93221:RO07_RS06580
uniprot id: A0A378Z2E9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS15935
gene id: 93221:RO07_RS15935
uniprot id: A0A378ZBH2
names: Similarity
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family.
messages: Homopolymer.

93221:RO07 RS09625
gene id: 93221:RO07_RS09625
uniprot id: A0A378YZL9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 49 kDa subunit family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS05615
gene id: 93221:RO07_RS05615
uniprot id: A0A378Z226
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS01375
gene id: 93221:RO07_RS01375
uniprot id: A0A378Z6D1
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS17720
gene id: 93221:RO07_RS17720
uniprot id: A0A378Z9P8
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS13245
gene id: 93221:RO07_RS13245
uniprot id: A0A378ZE84
names: Similarity
messages: Belongs to the DSD1 family.

93221:RO07 RS09470
gene id: 93221:RO07_RS09470
uniprot id: A0A378Z1W7
names: Activity Regulation
names: Caution
names: Function
names: Miscellaneous
names: Similarity
names: Subunit
messages: Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.
messages: Belongs to the CTP synthase family.
messages: CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS21040
gene id: 93221:RO07_RS21040
uniprot id: A0A378Z993
names: Function
names: Similarity
names: Subunit
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
messages: Homotetramer.

93221:RO07 RS15125
gene id: 93221:RO07_RS15125
uniprot id: A0A378ZBV3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

93221:RO07 RS23905
gene id: 93221:RO07_RS23905
uniprot id: A0A378Z652
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.
messages: Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.

93221:RO07 RS09810
gene id: 93221:RO07_RS09810
uniprot id: A0A378YZJ3
names: Function
names: Similarity
messages: Belongs to the LDH/MDH superfamily. MDH type 2 family.
messages: Catalyzes the reversible oxidation of malate to oxaloacetate.

93221:RO07 RS02280
gene id: 93221:RO07_RS02280
uniprot id: A0A378Z4T1
names: Similarity
messages: Belongs to the peptidase S11 family.

93221:RO07 RS01390
gene id: 93221:RO07_RS01390
uniprot id: A0A378Z4H4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the LamB/PxpA family.
messages: Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
messages: Forms a complex composed of PxpA, PxpB and PxpC.

93221:RO07 RS10145
gene id: 93221:RO07_RS10145
uniprot id: A0A378Z1J7
names: Caution
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Rho family.
messages: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.
messages: Homohexamer. The homohexamer assembles into an open ring structure.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS04285
gene id: 93221:RO07_RS04285
uniprot id: A0A378Z476
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
messages: Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.
messages: Cytoplasm

93221:RO07 RS07335
gene id: 93221:RO07_RS07335
uniprot id: A0A378Z304
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane

93221:RO07 RS07735
gene id: 93221:RO07_RS07735
uniprot id: A0A378Z1Q0
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

93221:RO07 RS06645
gene id: 93221:RO07_RS06645
uniprot id: A0A378Z3A1
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
messages: Belongs to the topoisomerase GyrA/ParC subunit family.
messages: Belongs to the type II topoisomerase GyrA/ParC subunit family.
messages: Cytoplasm
messages: Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.
messages: Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

93221:RO07 RS14585
gene id: 93221:RO07_RS14585
uniprot id: A0A378ZBF2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS02470
gene id: 93221:RO07_RS02470
uniprot id: A0A378Z3W5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
messages: Cytoplasm
messages: Homodimer.
messages: Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.

93221:RO07 RS07960
gene id: 93221:RO07_RS07960
uniprot id: A0A378Z2I8
names: Similarity
messages: Belongs to the ETF alpha-subunit/FixB family.

93221:RO07 RS04660
gene id: 93221:RO07_RS04660
uniprot id: A0A378Z4Q2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

93221:RO07 RS04255
gene id: 93221:RO07_RS04255
uniprot id: A0A378Z2S6
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.
messages: Binds 2 Zn(2+) ions per subunit.
messages: Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.
messages: Homodimer.

93221:RO07 RS23375
gene id: 93221:RO07_RS23375
uniprot id: A0A378Z7Z1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0056 (MarC) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS05910
gene id: 93221:RO07_RS05910
uniprot id: A0A378Z1W4
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

93221:RO07 RS03325
gene id: 93221:RO07_RS03325
uniprot id: A0A378Z3D1
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS10125
gene id: 93221:RO07_RS10125
uniprot id: A0A378YZD1
names: Similarity
messages: Belongs to the peptidase C40 family.

93221:RO07 RS00625
gene id: 93221:RO07_RS00625
uniprot id: A0A378Z6H5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DoxX family.
messages: Membrane

93221:RO07 RS22170
gene id: 93221:RO07_RS22170
uniprot id: A0A378Z7V6
names: Function
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).

93221:RO07 RS19895
gene id: 93221:RO07_RS19895
uniprot id: A0A378Z8E7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

93221:RO07 RS11270
gene id: 93221:RO07_RS11270
uniprot id: A0A378Z0M7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ClpA/ClpB family.
messages: Cytoplasm
messages: Homohexamer. The oligomerization is ATP-dependent.
messages: Homohexamer; The oligomerization is ATP-dependent.
messages: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.

93221:RO07 RS15975
gene id: 93221:RO07_RS15975
uniprot id: A0A378ZAL7
names: Similarity
messages: Belongs to the glycerate kinase type-1 family.

93221:RO07 RS24915
gene id: 93221:RO07_RS24915
uniprot id: A0A378Z7E0
names: Function
names: Similarity
messages: Belongs to the FlgN family.
messages: Required for the efficient initiation of filament assembly.

93221:RO07 RS04080
gene id: 93221:RO07_RS04080
uniprot id: A0A378Z4A9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the serine/threonine dehydratase family.
messages: Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
messages: Homotetramer.

93221:RO07 RS01330
gene id: 93221:RO07_RS01330
uniprot id: A0A378Z6E0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UreD family.
messages: Cytoplasm
messages: Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
messages: UreD, UreF and UreG form a complex that acts as a GTP-hydrolysis-dependent molecular chaperone, activating the urease apoprotein by helping to assemble the nickel containing metallocenter of UreC. The UreE protein probably delivers the nickel.

93221:RO07 RS20655
gene id: 93221:RO07_RS20655
uniprot id: A0A378Z7Z7
names: Similarity
messages: Belongs to the DapA family.

93221:RO07 RS24225
gene id: 93221:RO07_RS24225
uniprot id: A0A378Z7S4
names: Similarity
messages: Belongs to the oxoprolinase family.

93221:RO07 RS16970
gene id: 93221:RO07_RS16970
uniprot id: A0A378ZC80
names: Similarity
names: Subunit
messages: Belongs to the CarA family.
messages: Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.

93221:RO07 RS19685
gene id: 93221:RO07_RS19685
uniprot id: A0A378Z9M1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone-like protein H-NS family.
messages: nucleoid

93221:RO07 RS17945
gene id: 93221:RO07_RS17945
uniprot id: A0A378Z9H9
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS05520
gene id: 93221:RO07_RS05520
uniprot id: A0A378Z3U7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ExbD/TolR family.
messages: Cell membrane

93221:RO07 RS11040
gene id: 93221:RO07_RS11040
uniprot id: A0A378Z0K3
names: Similarity
messages: Belongs to the acyl coenzyme A hydrolase family.

93221:RO07 RS07850
gene id: 93221:RO07_RS07850
uniprot id: A0A378Z2V1
names: Similarity
messages: Belongs to the 4-hydroxy-2-oxovalerate aldolase family.

93221:RO07 RS14020
gene id: 93221:RO07_RS14020
uniprot id: A0A378ZCJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI family.
messages: Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.
messages: Cytoplasm

93221:RO07 RS13200
gene id: 93221:RO07_RS13200
uniprot id: A0A378ZE93
names: Similarity
messages: Belongs to the methyl-accepting chemotaxis (MCP) protein family.

93221:RO07 RS17710
gene id: 93221:RO07_RS17710
uniprot id: A0A378Z9P7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHMT family.
messages: Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS22475
gene id: 93221:RO07_RS22475
uniprot id: A0A378Z716
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEDS family. FtsW subfamily.
messages: Cell inner membrane
messages: Membrane
messages: Peptidoglycan polymerase that is essential for cell division.

93221:RO07 RS09650
gene id: 93221:RO07_RS09650
uniprot id: A0A378Z194
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 23 kDa subunit family.
messages: Binds 2 [4Fe-4S] clusters per subunit.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS15840
gene id: 93221:RO07_RS15840
uniprot id: A0A378ZAQ9
names: Similarity
messages: Belongs to the RutC family.

93221:RO07 RS09185
gene id: 93221:RO07_RS09185
uniprot id: A0A378Z1W6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15265
gene id: 93221:RO07_RS15265
uniprot id: A0A378ZD30
names: Similarity
names: Subunit
messages: Belongs to the bacterial ribosomal protein bL31 family.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS23760
gene id: 93221:RO07_RS23760
uniprot id: A0A378Z6Y4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL4 family.
messages: Forms part of the polypeptide exit tunnel.
messages: One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.
messages: Part of the 50S ribosomal subunit.

93221:RO07 RS13440
gene id: 93221:RO07_RS13440
uniprot id: A0A378ZDK4
names: Similarity
messages: Belongs to the enoyl-CoA hydratase/isomerase family.

93221:RO07 RS07595
gene id: 93221:RO07_RS07595
uniprot id: A0A378Z1S8
names: Similarity
names: Subunit
messages: Belongs to the methylaspartate ammonia-lyase family.
messages: Homodimer.

93221:RO07 RS25350
gene id: 93221:RO07_RS25350
uniprot id: A0A378Z5B8
names: Function
names: Similarity
messages: Belongs to the 2H phosphoesterase superfamily. ThpR family.
messages: Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.

93221:RO07 RS11565
gene id: 93221:RO07_RS11565
uniprot id: A0A378Z0S1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SmpB family.
messages: Cytoplasm
messages: Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.

93221:RO07 RS02455
gene id: 93221:RO07_RS02455
uniprot id: A0A378Z4S9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SecB family.
messages: Cytoplasm
messages: Homotetramer, a dimer of dimers. One homotetramer interacts with 1 SecA dimer.
messages: One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA.

93221:RO07 RS17050
gene id: 93221:RO07_RS17050
uniprot id: A0A378ZA23
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS00245
gene id: 93221:RO07_RS00245
uniprot id: A0A378Z6F2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS06510
gene id: 93221:RO07_RS06510
uniprot id: A0A378Z335
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS10355
gene id: 93221:RO07_RS10355
uniprot id: A0A378Z153
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.

93221:RO07 RS13020
gene id: 93221:RO07_RS13020
uniprot id: A0A379LRH3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS11575
gene id: 93221:RO07_RS11575
uniprot id: A0A378Z0M5
names: Similarity
messages: Belongs to the UPF0125 (RnfH) family.

93221:RO07 RS20760
gene id: 93221:RO07_RS20760
uniprot id: A0A378Z7Y1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17740
gene id: 93221:RO07_RS17740
uniprot id: A0A378ZAF5
names: Subunit
messages: Homodimer.

93221:RO07 RS05980
gene id: 93221:RO07_RS05980
uniprot id: A0A378Z1S1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
messages: Membrane

93221:RO07 RS15095
gene id: 93221:RO07_RS15095
uniprot id: A0A378ZB29
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS16940
gene id: 93221:RO07_RS16940
uniprot id: A0A378ZB44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.
messages: Cytoplasm
messages: Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.

93221:RO07 RS07830
gene id: 93221:RO07_RS07830
uniprot id: A0A378Z0P3
names: Similarity
messages: Belongs to the bacterial histone-like protein family.

93221:RO07 RS00220
gene id: 93221:RO07_RS00220
uniprot id: A0A378Z575
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NiCoT transporter (TC 2.A.52) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23380
gene id: 93221:RO07_RS23380
uniprot id: A0A378Z893
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.
messages: Cytoplasm

93221:RO07 RS09340
gene id: 93221:RO07_RS09340
uniprot id: A0A378YZT0
names: Function
names: Similarity
messages: A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
messages: Belongs to the NifU family.

93221:RO07 RS16985
gene id: 93221:RO07_RS16985
uniprot id: A0A378ZAV5
names: Similarity
messages: Belongs to the allantoicase family.

93221:RO07 RS00990
gene id: 93221:RO07_RS00990
uniprot id: A0A378Z619
names: Similarity
messages: Belongs to the Fur family.

93221:RO07 RS05425
gene id: 93221:RO07_RS05425
uniprot id: A0A378Z413
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS00795
gene id: 93221:RO07_RS00795
uniprot id: A0A378Z4U3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transpeptidase family. MrdA subfamily.
messages: Catalyzes cross-linking of the peptidoglycan cell wall.
messages: Cell inner membrane

93221:RO07 RS13910
gene id: 93221:RO07_RS13910
uniprot id: A0A378ZBS5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transglycosylase MltG family.
messages: Cell inner membrane
messages: Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.

93221:RO07 RS02295
gene id: 93221:RO07_RS02295
uniprot id: A0A378Z5L5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS21710
gene id: 93221:RO07_RS21710
uniprot id: A0A378Z7E2
names: Cofactor
names: Similarity
messages: Belongs to the rubredoxin family.
messages: Binds 1 Fe(3+) ion per subunit.

93221:RO07 RS25010
gene id: 93221:RO07_RS25010
uniprot id: A0A378Z5I7
names: Similarity
messages: Belongs to the MotB family.

93221:RO07 RS11630
gene id: 93221:RO07_RS11630
uniprot id: A0A378Z084
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS21770
gene id: 93221:RO07_RS21770
uniprot id: A0A378Z7G1
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS15775
gene id: 93221:RO07_RS15775
uniprot id: A0A378ZAQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

93221:RO07 RS25200
gene id: 93221:RO07_RS25200
uniprot id: A0A378Z5E7
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS02020
gene id: 93221:RO07_RS02020
uniprot id: A0A378Z465
names: Similarity
messages: Belongs to the UPF0225 family.

93221:RO07 RS04275
gene id: 93221:RO07_RS04275
uniprot id: A0A378Z4P7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uL13 family.
messages: Part of the 50S ribosomal subunit.
messages: This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.

93221:RO07 RS18445
gene id: 93221:RO07_RS18445
uniprot id: A0A378ZBB1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Cyclase 1 superfamily. KynB family.
messages: Binds 2 zinc ions per subunit.
messages: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L-kynurenine, the second step in the kynurenine pathway of tryptophan degradation.
messages: Homodimer.

93221:RO07 RS10115
gene id: 93221:RO07_RS10115
uniprot id: A0A378Z109
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS06530
gene id: 93221:RO07_RS06530
uniprot id: A0A378Z2F0
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

93221:RO07 RS23370
gene id: 93221:RO07_RS23370
uniprot id: A0A378Z8G2
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Heterodimer of HisH and HisF.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.

93221:RO07 RS22020
gene id: 93221:RO07_RS22020
uniprot id: A0A378Z803
names: Cofactor
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PdxA family.
messages: Binds 1 divalent metal cation per subunit. Can use ions such as Zn(2+), Mg(2+) or Co(2+).
messages: Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L-threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
messages: Cytoplasm
messages: Homodimer.
messages: The active site is located at the dimer interface.

93221:RO07 RS06390
gene id: 93221:RO07_RS06390
uniprot id: A0A378Z3E8
names: Similarity
messages: Belongs to the TPP enzyme family.

93221:RO07 RS04655
gene id: 93221:RO07_RS04655
uniprot id: A0A378Z2I9
names: Similarity
messages: Belongs to the pirin family.

93221:RO07 RS00340
gene id: 93221:RO07_RS00340
uniprot id: A0A378Z6D6
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

93221:RO07 RS14005
gene id: 93221:RO07_RS14005
uniprot id: A0A378ZBN5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: In the N-terminal section; belongs to the FGAMS family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Monomer.
messages: Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.

93221:RO07 RS16220
gene id: 93221:RO07_RS16220
uniprot id: A0A378ZC55
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DnaG primase family.
messages: Binds 1 zinc ion per monomer.
messages: Contains an N-terminal zinc-binding domain, a central core domain that contains the primase activity, and a C-terminal DnaB-binding domain.
messages: Monomer. Interacts with DnaB.
messages: RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.

93221:RO07 RS11955
gene id: 93221:RO07_RS11955
uniprot id: A0A378Z0I3
names: Cofactor
names: Similarity
messages: Belongs to the complex I 24 kDa subunit family.
messages: Binds 1 [2Fe-2S] cluster.

93221:RO07 RS03375
gene id: 93221:RO07_RS03375
uniprot id: A0A378Z3B9
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS09910
gene id: 93221:RO07_RS09910
uniprot id: A0A378YZH0
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

93221:RO07 RS00440
gene id: 93221:RO07_RS00440
uniprot id: A0A378Z6B8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS03595
gene id: 93221:RO07_RS03595
uniprot id: A0A378Z5B0
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

93221:RO07 RS17480
gene id: 93221:RO07_RS17480
uniprot id: A0A378ZBY1
names: Caution
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the FBPase class 1 family.
messages: Binds 2 magnesium ions per subunit.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS00905
gene id: 93221:RO07_RS00905
uniprot id: A0A378Z5I8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GSP F family.
messages: Membrane

93221:RO07 RS04845
gene id: 93221:RO07_RS04845
uniprot id: A0A378Z2E1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliP/MopC/SpaP family.
messages: Cell membrane
messages: Membrane
messages: Plays a role in the flagellum-specific transport system.

93221:RO07 RS08165
gene id: 93221:RO07_RS08165
uniprot id: A0A378Z2G8
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
messages: In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93221:RO07 RS04800
gene id: 93221:RO07_RS04800
uniprot id: A0A378Z2K6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum
messages: Belongs to the bacterial flagellin family.
messages: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
messages: Secreted

93221:RO07 RS01015
gene id: 93221:RO07_RS01015
uniprot id: A0A378Z4S0
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: A double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer. The assembly of the HslU/HslV complex is dependent on binding of ATP.
messages: Allosterically activated by HslU binding.
messages: Belongs to the peptidase T1B family. HslV subfamily.
messages: Cytoplasm
messages: Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.

93221:RO07 RS21920
gene id: 93221:RO07_RS21920
uniprot id: A0A378Z824
names: Similarity
messages: Belongs to the UPF0229 family.

93221:RO07 RS19460
gene id: 93221:RO07_RS19460
uniprot id: A0A378ZAP4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Iojap/RsfS family.
messages: Cytoplasm
messages: Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
messages: Interacts with ribosomal protein L14 (rplN).

93221:RO07 RS15365
gene id: 93221:RO07_RS15365
uniprot id: A0A378ZAX8
names: Similarity
messages: Belongs to the sigma-70 factor family. ECF subfamily.

93221:RO07 RS21585
gene id: 93221:RO07_RS21585
uniprot id: A0A378Z9A5
names: Function
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.
messages: Belongs to the UppP family.
messages: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23580
gene id: 93221:RO07_RS23580
uniprot id: A0A378Z851
names: Function
names: Similarity
names: Subunit
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.
messages: Homodimer.
messages: Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.

93221:RO07 RS05850
gene id: 93221:RO07_RS05850
uniprot id: A0A378Z2X1
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliG family.
messages: Membrane

93221:RO07 RS08440
gene id: 93221:RO07_RS08440
uniprot id: A0A378Z287
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS17545
gene id: 93221:RO07_RS17545
uniprot id: A0A378ZAU3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

93221:RO07 RS18805
gene id: 93221:RO07_RS18805
uniprot id: A0A378Z906
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS09610
gene id: 93221:RO07_RS09610
uniprot id: A0A378YZN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I subunit 3 family.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS15955
gene id: 93221:RO07_RS15955
uniprot id: A0A378ZBG0
names: Activity Regulation
names: Caution
names: Function
names: Similarity
messages: Belongs to the FGGY kinase family.
messages: Inhibited by fructose 1,6-bisphosphate (FBP).
messages: Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS02715
gene id: 93221:RO07_RS02715
uniprot id: A0A378Z543
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the FPG family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
messages: Monomer.

93221:RO07 RS03255
gene id: 93221:RO07_RS03255
uniprot id: A0A378Z4A8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS22185
gene id: 93221:RO07_RS22185
uniprot id: A0A378Z8M7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mediates influx of magnesium ions.
messages: Membrane

93221:RO07 RS04350
gene id: 93221:RO07_RS04350
uniprot id: A0A378Z2U6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HemJ family.
messages: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
messages: Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.
messages: Cell membrane
messages: Homodimer.
messages: Membrane

93221:RO07 RS24340
gene id: 93221:RO07_RS24340
uniprot id: A0A378Z5W7
names: Similarity
messages: Belongs to the 5'-nucleotidase family.

93221:RO07 RS20835
gene id: 93221:RO07_RS20835
uniprot id: A0A378Z9D5
names: Similarity
messages: Belongs to the LysR transcriptional regulatory family.

93221:RO07 RS06545
gene id: 93221:RO07_RS06545
uniprot id: A0A378Z3C0
names: Subcellular Location Annotation
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS25305
gene id: 93221:RO07_RS25305
uniprot id: A0A378Z7B3
names: Function
names: Similarity
messages: ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.
messages: Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.

93221:RO07 RS22955
gene id: 93221:RO07_RS22955
uniprot id: A0A378Z871
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AlgF family.
messages: Periplasm

93221:RO07 RS01235
gene id: 93221:RO07_RS01235
uniprot id: A0A378Z5H2
names: Similarity
messages: Belongs to the bacterial solute-binding protein 5 family.

93221:RO07 RS02575
gene id: 93221:RO07_RS02575
uniprot id: A0A378Z4L2
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS06280
gene id: 93221:RO07_RS06280
uniprot id: A0A378Z1L5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS25385
gene id: 93221:RO07_RS25385
uniprot id: A0A378Z5A6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
messages: Cell membrane
messages: Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.

93221:RO07 RS19880
gene id: 93221:RO07_RS19880
uniprot id: A0A378Z988
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the IspH family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis.

93221:RO07 RS14525
gene id: 93221:RO07_RS14525
uniprot id: A0A378ZBE3
names: Subcellular Location Annotation
messages: Cytoplasm

93221:RO07 RS10830
gene id: 93221:RO07_RS10830
uniprot id: A0A378Z0N8
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13265
gene id: 93221:RO07_RS13265
uniprot id: A0A378ZD92
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS13995
gene id: 93221:RO07_RS13995
uniprot id: A0A378ZCG9
names: Similarity
messages: Belongs to the BolA/IbaG family.

93221:RO07 RS06735
gene id: 93221:RO07_RS06735
uniprot id: A0A378Z1C4
names: Similarity
messages: Belongs to the histone deacetylase family.

93221:RO07 RS19620
gene id: 93221:RO07_RS19620
uniprot id: A0A378ZA30
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS12115
gene id: 93221:RO07_RS12115
uniprot id: A0A378YZE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. TCR/Tet family.
messages: Membrane
messages: Resistance to tetracycline by an active tetracycline efflux. This is an energy-dependent process that decreases the accumulation of the antibiotic in whole cells. This protein functions as a metal-tetracycline/H(+) antiporter.

93221:RO07 RS04595
gene id: 93221:RO07_RS04595
uniprot id: A0A378Z2K1
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the queuine tRNA-ribosyltransferase family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
messages: Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.

93221:RO07 RS23720
gene id: 93221:RO07_RS23720
uniprot id: A0A378Z887
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS17 family.
messages: One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
messages: Part of the 30S ribosomal subunit.

93221:RO07 RS02290
gene id: 93221:RO07_RS02290
uniprot id: A0A378Z632
names: Similarity
messages: Belongs to the UPF0250 family.

93221:RO07 RS20175
gene id: 93221:RO07_RS20175
uniprot id: A0A378Z9R7
names: Similarity
messages: Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.

93221:RO07 RS14705
gene id: 93221:RO07_RS14705
uniprot id: A0A378ZC33
names: Similarity
messages: Belongs to the GSP E family.

93221:RO07 RS02915
gene id: 93221:RO07_RS02915
uniprot id: A0A378Z4Z7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily.
messages: Homodimer.
messages: Involved in phosphonate degradation.

93221:RO07 RS09615
gene id: 93221:RO07_RS09615
uniprot id: A0A378YZW8
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I 20 kDa subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: Cell membrane
messages: NDH-1 is composed of 14 different subunits. Subunits NuoB, C, D, E, F, and G constitute the peripheral sector of the complex.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
messages: NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.

93221:RO07 RS07085
gene id: 93221:RO07_RS07085
uniprot id: A0A378Z285
names: Similarity
messages: Belongs to the P(II) protein family.

93221:RO07 RS04840
gene id: 93221:RO07_RS04840
uniprot id: A0A378Z2G4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Membrane

93221:RO07 RS12915
gene id: 93221:RO07_RS12915
uniprot id: A0A379LQT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 13 family.
messages: Cytoplasm

93221:RO07 RS11945
gene id: 93221:RO07_RS11945
uniprot id: A0A378YYL6
names: Similarity
messages: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.

93221:RO07 RS21475
gene id: 93221:RO07_RS21475
uniprot id: A0A378Z7J0
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS19465
gene id: 93221:RO07_RS19465
uniprot id: A0A378ZA62
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA methyltransferase RlmH family.
messages: Cytoplasm
messages: Homodimer.
messages: Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.

93221:RO07 RS24155
gene id: 93221:RO07_RS24155
uniprot id: A0A378Z6R2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) family.
messages: Membrane

93221:RO07 RS01345
gene id: 93221:RO07_RS01345
uniprot id: A0A378Z4I4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS04375
gene id: 93221:RO07_RS04375
uniprot id: A0A378Z3Q2
names: Similarity
messages: Belongs to the KHG/KDPG aldolase family.

93221:RO07 RS09480
gene id: 93221:RO07_RS09480
uniprot id: A0A378Z1Q8
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enolase family.
messages: Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
messages: Cell surface
messages: Cytoplasm
messages: Secreted
messages: The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.

93221:RO07 RS19390
gene id: 93221:RO07_RS19390
uniprot id: A0A378Z8Q5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS24840
gene id: 93221:RO07_RS24840
uniprot id: A0A378Z5M1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Bacterial flagellum basal body
messages: Belongs to the FliQ/MopD/SpaQ family.
messages: Cell membrane
messages: Membrane
messages: Role in flagellar biosynthesis.

93221:RO07 RS10090
gene id: 93221:RO07_RS10090
uniprot id: A0A378YZC7
names: Similarity
messages: Belongs to the FKBP-type PPIase family.

93221:RO07 RS20995
gene id: 93221:RO07_RS20995
uniprot id: A0A378Z9M3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Membrane

93221:RO07 RS01205
gene id: 93221:RO07_RS01205
uniprot id: A0A378Z4L4
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS18470
gene id: 93221:RO07_RS18470
uniprot id: A0A378Z978
names: Similarity
messages: Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.

93221:RO07 RS09115
gene id: 93221:RO07_RS09115
uniprot id: A0A378Z0X5
names: Similarity
messages: Belongs to the DNA photolyase family.

93221:RO07 RS04070
gene id: 93221:RO07_RS04070
uniprot id: A0A378Z4T7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP cyclohydrolase I family. QueF type 2 subfamily.
messages: Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1).
messages: Cytoplasm
messages: Homodimer.

93221:RO07 RS13090
gene id: 93221:RO07_RS13090
uniprot id: A0A379LRN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family. HisMQ subfamily.
messages: Cell membrane
messages: Membrane

93221:RO07 RS00770
gene id: 93221:RO07_RS00770
uniprot id: A0A378Z6V3
names: Cofactor
names: Similarity
messages: Belongs to the PTPS family. QueD subfamily.
messages: Binds 1 zinc ion per subunit.

93221:RO07 RS11315
gene id: 93221:RO07_RS11315
uniprot id: A0A378Z0X1
names: Cofactor
messages: Can also use Mn(2+) ion.

93221:RO07 RS07420
gene id: 93221:RO07_RS07420
uniprot id: A0A378Z0X3
names: Similarity
messages: Belongs to the proline racemase family.

93221:RO07 RS11435
gene id: 93221:RO07_RS11435
uniprot id: A0A378Z0C5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZipA family.
messages: Cell inner membrane
messages: Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.

93221:RO07 RS09460
gene id: 93221:RO07_RS09460
uniprot id: A0A378Z0Q6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS25155
gene id: 93221:RO07_RS25155
uniprot id: A0A378Z7E6
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS02600
gene id: 93221:RO07_RS02600
uniprot id: A0A378Z4P2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
messages: Cell inner membrane
messages: Membrane

93221:RO07 RS06070
gene id: 93221:RO07_RS06070
uniprot id: A0A378Z1Y3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS08050
gene id: 93221:RO07_RS08050
uniprot id: A0A378Z0J4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the binding-protein-dependent transport system permease family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS23680
gene id: 93221:RO07_RS23680
uniprot id: A0A378Z827
names: Domain
names: Function
names: Similarity
names: Subunit
messages: Belongs to the universal ribosomal protein uS5 family.
messages: Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.
messages: Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.
messages: The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.
messages: With S4 and S12 plays an important role in translational accuracy.

93221:RO07 RS20205
gene id: 93221:RO07_RS20205
uniprot id: A0A378Z8A5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DedA family.
messages: Cell membrane
messages: Membrane

93221:RO07 RS11495
gene id: 93221:RO07_RS11495
uniprot id: A0A378YYM6
names: Caution
names: Function
names: Similarity
messages: Belongs to the DXR family.
messages: Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

93221:RO07 RS03135
gene id: 93221:RO07_RS03135
uniprot id: A0A378Z3F3
names: Subcellular Location Annotation
messages: Membrane

93221:RO07 RS07995
gene id: 93221:RO07_RS07995
uniprot id: A0A378Z1K0
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

93221:RO07 RS13070
gene id: 93221:RO07_RS13070
uniprot id: A0A379LPG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TonB-dependent receptor family.
messages: Cell outer membrane

93221:RO07 RS13165
gene id: 93221:RO07_RS13165
uniprot id: A0A378ZCY2
names: Similarity
messages: In the C-terminal section; belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

93221:RO07 RS01820
gene id: 93221:RO07_RS01820
uniprot id: A0A378Z4A3
names: Similarity
messages: Belongs to the PhzF family.

93221:RO07 RS11455
gene id: 93221:RO07_RS11455
uniprot id: A0A378YZL5
names: Activity Regulation
names: Caution
names: Domain
names: Function
names: Similarity
messages: Belongs to the GlnD family.
messages: Has four distinct domains: an N-terminal nucleotidyltransferase (NT) domain responsible for UTase activity, a central HD domain that encodes UR activity, and two C-terminal ACT domains that seem to have a role in glutamine sensing.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
messages: Uridylyltransferase (UTase) activity is inhibited by glutamine, while glutamine activates uridylyl-removing (UR) activity.

93221:RO07 RS12830
gene id: 93221:RO07_RS12830
uniprot id: A0A379LRC9
names: Similarity
messages: Belongs to the MxiH/PrgI/YscF family.

93221:RO07 RS16030
gene id: 93221:RO07_RS16030
uniprot id: A0A378ZAL9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.