931890:Ecym 7031
gene id: 931890:Ecym_7031
uniprot id: G8JVM3
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IMPDH/GMPR family.
messages: Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
messages: Cytoplasm
messages: Homotetramer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.

931890:Ecym 4275
gene id: 931890:Ecym_4275
uniprot id: G8JTI6
names: Similarity
messages: Belongs to the LCL2 family.

931890:Ecym 5531
gene id: 931890:Ecym_5531
uniprot id: I6NDX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the methyltransferase superfamily. RRP8 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of adenine in helix 25.1 in 25S rRNA. Required both for ribosomal 40S and 60S subunits biogenesis. Required for efficient pre-rRNA cleavage at site A2.
messages: nucleolus

931890:Ecym 1038
gene id: 931890:Ecym_1038
uniprot id: G8JM36
names: Similarity
messages: Belongs to the hexokinase family.

931890:Ecym 6191
gene id: 931890:Ecym_6191
uniprot id: G8JV95
names: Similarity
messages: Belongs to the NFYB/HAP3 subunit family.

931890:Ecym 2624
gene id: 931890:Ecym_2624
uniprot id: G8JQK4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC3 family.
messages: Nucleus

931890:Ecym 7216
gene id: 931890:Ecym_7216
uniprot id: G8JW47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

931890:Ecym 6039
gene id: 931890:Ecym_6039
uniprot id: G8JUW4
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

931890:Ecym 8227
gene id: 931890:Ecym_8227
uniprot id: G8JXD8
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S2 family.

931890:Ecym 4322
gene id: 931890:Ecym_4322
uniprot id: G8JTN2
names: Function
names: Similarity
messages: Belongs to the ARPC5 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development.

931890:Ecym 2127
gene id: 931890:Ecym_2127
uniprot id: G8JNG4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP1 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication. Connects the central plaque of the SPB with the half-bridge. Required for proper localization of CDC5 at the SPB and for proper M-phase progression.
messages: spindle pole body

931890:Ecym 2439
gene id: 931890:Ecym_2439
uniprot id: G8JPB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

931890:Ecym 6187
gene id: 931890:Ecym_6187
uniprot id: G8JV91
names: Similarity
messages: Belongs to the DDI1 family.

931890:Ecym 3027
gene id: 931890:Ecym_3027
uniprot id: G8JQX3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2544
gene id: 931890:Ecym_2544
uniprot id: G8JQA6
names: Similarity
messages: Belongs to the SKP1 family.

931890:Ecym 5082
gene id: 931890:Ecym_5082
uniprot id: I6NCS9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6442
gene id: 931890:Ecym_6442
uniprot id: G8JUN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 7157
gene id: 931890:Ecym_7157
uniprot id: G8JVZ0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL43 family.

931890:Ecym 7451
gene id: 931890:Ecym_7451
uniprot id: G8JWQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.
messages: coated pit

931890:Ecym 2712
gene id: 931890:Ecym_2712
uniprot id: G8JPF1
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sterol desaturase family. SCS7 subfamily.
messages: Binds 2 Zn(2+) ions per subunit that likely form a catalytic dimetal center.
messages: Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5120
gene id: 931890:Ecym_5120
uniprot id: I6NCV8
names: Function
names: Similarity
messages: Belongs to the flavokinase family.
messages: Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) coenzyme.

931890:Ecym 5002
gene id: 931890:Ecym_5002
uniprot id: I6NCL3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 6223
gene id: 931890:Ecym_6223
uniprot id: G8JVC6
names: Similarity
messages: Belongs to the Rab GDI family.

931890:Ecym 4786
gene id: 931890:Ecym_4786
uniprot id: G8JSS5
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the sulfate adenylyltransferase family.
messages: Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids.
messages: Cytoplasm
messages: Homohexamer. Dimer of trimers.
messages: The oligomerization domain is distantly related to APS kinases, but it is not functional and does not bind APS. It is required for oligomerization of the enzyme, although the oligomerization state has no effect on the catalytic activity of the enzyme.

931890:Ecym 5550
gene id: 931890:Ecym_5550
uniprot id: I6NDZ8
names: Similarity
messages: Belongs to the SCC4/mau-2 family.

931890:Ecym 2190
gene id: 931890:Ecym_2190
uniprot id: G8JP34
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

931890:Ecym 1371
gene id: 931890:Ecym_1371
uniprot id: G8JNE0
names: Cofactor
names: Miscellaneous
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Rieske iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster per subunit.
messages: Membrane
messages: Mitochondrion inner membrane
messages: The Rieske protein is a high potential 2Fe-2S protein.

931890:Ecym 6097
gene id: 931890:Ecym_6097
uniprot id: G8JV14
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

931890:Ecym 3139
gene id: 931890:Ecym_3139
uniprot id: G8JR74
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

931890:Ecym 3290
gene id: 931890:Ecym_3290
uniprot id: G8JRL4
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

931890:Ecym 3494
gene id: 931890:Ecym_3494
uniprot id: G8JS56
names: Similarity
messages: Belongs to the SEC6 family.

931890:Ecym 3064
gene id: 931890:Ecym_3064
uniprot id: G8JR07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the tyrosyl-DNA phosphodiesterase family.
messages: Nucleus

931890:Ecym 5523
gene id: 931890:Ecym_5523
uniprot id: I6NDX2
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931890:Ecym 7192
gene id: 931890:Ecym_7192
uniprot id: G8JW25
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M48A family.
messages: Binds 1 zinc ion per subunit.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Proteolytically removes the C-terminal three residues of farnesylated proteins.

931890:Ecym 3046
gene id: 931890:Ecym_3046
uniprot id: G8JQZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 5163
gene id: 931890:Ecym_5163
uniprot id: I6NCZ6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 4186
gene id: 931890:Ecym_4186
uniprot id: G8JTA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCC2/Nipped-B family.
messages: Nucleus

931890:Ecym 3432
gene id: 931890:Ecym_3432
uniprot id: G8JRZ9
names: Similarity
messages: Belongs to the CCZ1 family.

931890:Ecym 3416
gene id: 931890:Ecym_3416
uniprot id: G8JRY3
names: Similarity
messages: Belongs to the DNA/RNA non-specific endonuclease family.

931890:Ecym 2669
gene id: 931890:Ecym_2669
uniprot id: G8JNV4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 7464
gene id: 931890:Ecym_7464
uniprot id: G8JWR8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GET2 family.
messages: Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER.

931890:Ecym 3035
gene id: 931890:Ecym_3035
uniprot id: G8JQY0
names: Similarity
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CDC5/Polo subfamily.

931890:Ecym 7133
gene id: 931890:Ecym_7133
uniprot id: G8JVW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 3349
gene id: 931890:Ecym_3349
uniprot id: G8JRR8
names: Similarity
messages: Belongs to the glycosyl hydrolase 38 family.

931890:Ecym 5675
gene id: 931890:Ecym_5675
uniprot id: I6NEB3
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8094
gene id: 931890:Ecym_8094
uniprot id: G8JX14
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGN subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor.
messages: Membrane

931890:Ecym 6015
gene id: 931890:Ecym_6015
uniprot id: G8JUU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRN7/TAF1B family.
messages: nucleolus

931890:Ecym 2191
gene id: 931890:Ecym_2191
uniprot id: G8JP35
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NIP7 family.
messages: Interacts with pre-ribosome complex.
messages: Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly.
messages: nucleolus

931890:Ecym 6273
gene id: 931890:Ecym_6273
uniprot id: G8JVH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT4 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.
messages: centromere

931890:Ecym 5309
gene id: 931890:Ecym_5309
uniprot id: G8JRQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 6249
gene id: 931890:Ecym_6249
uniprot id: G8JVF2
names: Similarity
messages: Belongs to the phosducin family.

931890:Ecym 2538
gene id: 931890:Ecym_2538
uniprot id: G8JQA0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 2612
gene id: 931890:Ecym_2612
uniprot id: G8JQJ2
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4221
gene id: 931890:Ecym_4221
uniprot id: G8JTD5
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

931890:Ecym 8239
gene id: 931890:Ecym_8239
uniprot id: G8JXE9
names: Similarity
messages: Belongs to the NUP186/NUP192/NUP205 family.

931890:Ecym 7016
gene id: 931890:Ecym_7016
uniprot id: G8JVK8
names: Similarity
messages: Belongs to the DOCK family.

931890:Ecym 4065
gene id: 931890:Ecym_4065
uniprot id: G8JSZ2
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

931890:Ecym 3571
gene id: 931890:Ecym_3571
uniprot id: G8JQQ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.
messages: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

931890:Ecym 2196
gene id: 931890:Ecym_2196
uniprot id: G8JP40
names: Similarity
messages: Belongs to the TYW1 family.

931890:Ecym 4057
gene id: 931890:Ecym_4057
uniprot id: G8JSY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD7 family.
messages: spindle pole

931890:Ecym 4044
gene id: 931890:Ecym_4044
uniprot id: G8JSX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD2 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 5363
gene id: 931890:Ecym_5363
uniprot id: I6NDH9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7299
gene id: 931890:Ecym_7299
uniprot id: G8JWC2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4024
gene id: 931890:Ecym_4024
uniprot id: G8JSV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the NDC80/HEC1 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

931890:Ecym 5538
gene id: 931890:Ecym_5538
uniprot id: I6NDY6
names: Similarity
messages: Belongs to the MYG1 family.

931890:Ecym 8021
gene id: 931890:Ecym_8021
uniprot id: G8JWU3
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the proteasome subunit S1 family.

931890:Ecym 1114
gene id: 931890:Ecym_1114
uniprot id: G8JM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

931890:Ecym 2350
gene id: 931890:Ecym_2350
uniprot id: G8JNL6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAPT1 family.
messages: Membrane

931890:Ecym 7121
gene id: 931890:Ecym_7121
uniprot id: G8JVV6
names: Function
names: Similarity
messages: Belongs to the ATPase alpha/beta chains family.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

931890:Ecym 2677
gene id: 931890:Ecym_2677
uniprot id: G8JNW2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ANKZF1/VMS1 family.
messages: Cytoplasm

931890:Ecym 1236
gene id: 931890:Ecym_1236
uniprot id: G8JN18
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5458
gene id: 931890:Ecym_5458
uniprot id: I6NDR5
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

931890:Ecym 3507
gene id: 931890:Ecym_3507
uniprot id: G8JS66
names: Similarity
messages: Belongs to the RecA family. DMC1 subfamily.

931890:Ecym 4656
gene id: 931890:Ecym_4656
uniprot id: G8JSF6
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

931890:Ecym 6231
gene id: 931890:Ecym_6231
uniprot id: G8JVD4
names: Function
names: Similarity
messages: Belongs to the IPP transferase family.
messages: Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37.

931890:Ecym 8027
gene id: 931890:Ecym_8027
uniprot id: G8JWU9
names: Similarity
messages: Belongs to the peptidase M24B family.

931890:Ecym 2279
gene id: 931890:Ecym_2279
uniprot id: G8JPS0
names: Function
names: Similarity
messages: Belongs to the SWC5 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

931890:Ecym 4220
gene id: 931890:Ecym_4220
uniprot id: G8JTD4
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

931890:Ecym 1376
gene id: 931890:Ecym_1376
uniprot id: G8JNE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the chloride channel (TC 2.A.49) family.
messages: Membrane

931890:Ecym 7112
gene id: 931890:Ecym_7112
uniprot id: G8JVU9
names: Similarity
messages: Belongs to the HGH1 family.

931890:Ecym 6285
gene id: 931890:Ecym_6285
uniprot id: G8JVI6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COA3 family.
messages: Component of 250-400 kDa complexes called cytochrome oxidase assembly intermediates or COA complexes.
messages: Required for assembly of cytochrome c oxidase (complex IV).

931890:Ecym 2270
gene id: 931890:Ecym_2270
uniprot id: G8JPR1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. mRNA cap 0 methyltransferase family.
messages: In the N-terminal section; belongs to the dsDNA virus mRNA guanylyltransferase family.
messages: Nucleus
messages: Responsible for methylating the 5'-cap structure of mRNAs.

931890:Ecym 2134
gene id: 931890:Ecym_2134
uniprot id: G8JNH0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC4 family.
messages: Mitochondrion intermembrane space

931890:Ecym 1062
gene id: 931890:Ecym_1062
uniprot id: G8JMB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

931890:Ecym 4430
gene id: 931890:Ecym_4430
uniprot id: G8JTX4
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 2070
gene id: 931890:Ecym_2070
uniprot id: G8JPH8
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

931890:Ecym 6418
gene id: 931890:Ecym_6418
uniprot id: G8JUL0
names: Similarity
messages: Belongs to the universal ribosomal protein uL22 family.

931890:Ecym 5540
gene id: 931890:Ecym_5540
uniprot id: I6NDY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

931890:Ecym 6037
gene id: 931890:Ecym_6037
uniprot id: G8JUW2
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

931890:Ecym 6092
gene id: 931890:Ecym_6092
uniprot id: G8JV09
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 2078
gene id: 931890:Ecym_2078
uniprot id: G8JPI5
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG10 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 2693
gene id: 931890:Ecym_2693
uniprot id: G8JPD5
names: Similarity
messages: Belongs to the SAP30 family.

931890:Ecym 3540
gene id: 931890:Ecym_3540
uniprot id: G8JQN2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

931890:Ecym 8022
gene id: 931890:Ecym_8022
uniprot id: G8JWU4
names: Similarity
messages: Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.

931890:Ecym 1402
gene id: 931890:Ecym_1402
uniprot id: G8JM60
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

931890:Ecym 2806
gene id: 931890:Ecym_2806
uniprot id: G8JQE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase epsilon subunit B family.
messages: Nucleus

931890:Ecym 3335
gene id: 931890:Ecym_3335
uniprot id: G8JRQ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 6391
gene id: 931890:Ecym_6391
uniprot id: G8JUI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INSIG family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2018
gene id: 931890:Ecym_2018
uniprot id: G8JNX7
names: Similarity
messages: Belongs to the CDC50/LEM3 family.

931890:Ecym 4719
gene id: 931890:Ecym_4719
uniprot id: G8JSL7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

931890:Ecym 3319
gene id: 931890:Ecym_3319
uniprot id: G8JRP1
names: Similarity
messages: Belongs to the PIGH family.

931890:Ecym 8076
gene id: 931890:Ecym_8076
uniprot id: G8JWZ8
names: Similarity
messages: Belongs to the proteasome subunit p55 family.

931890:Ecym 1120
gene id: 931890:Ecym_1120
uniprot id: G8JML9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UbiH/COQ6 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl-4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6.
messages: Mitochondrion inner membrane

931890:Ecym 5348
gene id: 931890:Ecym_5348
uniprot id: I6NDG5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DAD/OST2 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

931890:Ecym 7058
gene id: 931890:Ecym_7058
uniprot id: G8JVP6
names: Similarity
messages: Belongs to the threonine aldolase family.

931890:Ecym 4203
gene id: 931890:Ecym_4203
uniprot id: G8JTB8
names: Similarity
messages: Belongs to the inositol phosphokinase (IPK) family.

931890:Ecym 4036
gene id: 931890:Ecym_4036
uniprot id: G8JSW5
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M48 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 7354
gene id: 931890:Ecym_7354
uniprot id: G8JWG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCR4/nocturin family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 8317
gene id: 931890:Ecym_8317
uniprot id: G8JXM1
names: Similarity
messages: Belongs to the WD repeat G protein beta family.

931890:Ecym 2257
gene id: 931890:Ecym_2257
uniprot id: G8JPP8
names: Similarity
messages: Belongs to the glutathione peroxidase family.

931890:Ecym 8057
gene id: 931890:Ecym_8057
uniprot id: G8JWX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: GTP-binding protein involved in protein trafficking; modulates vesicle budding and uncoating within the Golgi apparatus.
messages: Golgi apparatus

931890:Ecym 8061
gene id: 931890:Ecym_8061
uniprot id: G8JWY3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC31 family.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2467
gene id: 931890:Ecym_2467
uniprot id: G8JPT5
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 8033
gene id: 931890:Ecym_8033
uniprot id: G8JWV5
names: Similarity
messages: Belongs to the IMPACT family.

931890:Ecym 7434
gene id: 931890:Ecym_7434
uniprot id: G8JWP0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TEC1 family.
messages: Nucleus

931890:Ecym 4072
gene id: 931890:Ecym_4072
uniprot id: G8JSZ9
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL33 family.

931890:Ecym 6168
gene id: 931890:Ecym_6168
uniprot id: G8JV74
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
messages: Belongs to the replication factor A protein 1 family.
messages: Component of the heterotrimeric canonical replication protein A complex (RPA).
messages: Nucleus

931890:Ecym 1009
gene id: 931890:Ecym_1009
uniprot id: G8JM08
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KRR1 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Interacts with snoRNA U3. Interacts with MPP10, KRI1 and with ribosomal proteins RPS1A, RPS4A, RPS4B, RPS8A, RPS8B, RPS11A, RPS11B, RPS13, RPS24, RPS25, RPL4A, RPL7B, RPL8, RPL23, RPL25 and RPL28.
messages: Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. Essential for vegetative growth.
messages: nucleolus

931890:Ecym 4772
gene id: 931890:Ecym_4772
uniprot id: G8JSR2
names: Similarity
messages: Belongs to the GTP cyclohydrolase I family.

931890:Ecym 5378
gene id: 931890:Ecym_5378
uniprot id: I6NDJ1
names: Similarity
messages: Belongs to the MAD2 family.

931890:Ecym 5101
gene id: 931890:Ecym_5101
uniprot id: I6NCU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

931890:Ecym 7374
gene id: 931890:Ecym_7374
uniprot id: G8JWI5
names: Similarity
messages: Belongs to the IlvD/Edd family.

931890:Ecym 3307
gene id: 931890:Ecym_3307
uniprot id: G8JRM9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRA1 family.
messages: Membrane

931890:Ecym 8182
gene id: 931890:Ecym_8182
uniprot id: G8JX94
names: Similarity
messages: Belongs to the terpene cyclase/mutase family.

931890:Ecym 2290
gene id: 931890:Ecym_2290
uniprot id: G8JPS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nucleoporin GLFG family.
messages: Nucleus membrane
messages: nuclear pore complex

931890:Ecym 3538
gene id: 931890:Ecym_3538
uniprot id: G8JQN1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COPG family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

931890:Ecym 5011
gene id: 931890:Ecym_5011
uniprot id: I6NCM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-22 family.
messages: Involved in peroxisome biogenesis.
messages: Membrane
messages: Peroxisome membrane

931890:Ecym 1456
gene id: 931890:Ecym_1456
uniprot id: G8JMG5
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2294
gene id: 931890:Ecym_2294
uniprot id: G8JQ34
names: Similarity
messages: Belongs to the NDK family.

931890:Ecym 3389
gene id: 931890:Ecym_3389
uniprot id: G8JRV7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1138
gene id: 931890:Ecym_1138
uniprot id: G8JMN5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL6 family.

931890:Ecym 4677
gene id: 931890:Ecym_4677
uniprot id: G8JSH6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 1306
gene id: 931890:Ecym_1306
uniprot id: G8JN80
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

931890:Ecym 2590
gene id: 931890:Ecym_2590
uniprot id: G8JQH2
names: Similarity
messages: Belongs to the XPO2/CSE1 family.

931890:Ecym 2141
gene id: 931890:Ecym_2141
uniprot id: G8JNH7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5301
gene id: 931890:Ecym_5301
uniprot id: I6NDC1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGV family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis.
messages: Membrane

931890:Ecym 1276
gene id: 931890:Ecym_1276
uniprot id: G8JN53
names: Function
names: Similarity
messages: Belongs to the glycosyltransferase 3 family.
messages: Transfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.

931890:Ecym 4657
gene id: 931890:Ecym_4657
uniprot id: G8JSF7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

931890:Ecym 4602
gene id: 931890:Ecym_4602
uniprot id: G8JSB1
names: Function
names: Similarity
messages: Belongs to the thiolase-like superfamily. HMG-CoA synthase family.
messages: Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA.

931890:Ecym 6036
gene id: 931890:Ecym_6036
uniprot id: G8JUW1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2557
gene id: 931890:Ecym_2557
uniprot id: G8JQB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MIP/aquaporin (TC 1.A.8) family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 1266
gene id: 931890:Ecym_1266
uniprot id: G8JN44
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

931890:Ecym 3531
gene id: 931890:Ecym_3531
uniprot id: G8JQM4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ERF4 family.
messages: Endoplasmic reticulum membrane
messages: Interacts with ERF2.

931890:Ecym 2632
gene id: 931890:Ecym_2632
uniprot id: G8JNR9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1296
gene id: 931890:Ecym_1296
uniprot id: G8JN70
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.
messages: Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
messages: Homodimer.

931890:Ecym 6224
gene id: 931890:Ecym_6224
uniprot id: G8JVC7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: Nucleus

931890:Ecym 3412
gene id: 931890:Ecym_3412
uniprot id: G8JRX9
names: Similarity
messages: Belongs to the SURF6 family.

931890:Ecym 4470
gene id: 931890:Ecym_4470
uniprot id: G8JU07
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM21 family.
messages: Involved in mitochondrial migration along actin filaments.
messages: actin patch

931890:Ecym 2705
gene id: 931890:Ecym_2705
uniprot id: G8JPE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.
messages: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
messages: Homodimer.

931890:Ecym 2240
gene id: 931890:Ecym_2240
uniprot id: G8JPN2
names: Activity Regulation
names: Caution
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C19 family. PAN2 subfamily.
messages: Binds 2 metal cations per subunit in the catalytic exonuclease domain.
messages: Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails.
messages: Contains a pseudo-UCH domain. This ubiquitin C-terminal hydrolase (UCH)-like or ubiquitin specific protease (USP)-like domain is predicted to be catalytically inactive because it lacks the active site catalytic triad characteristic of thiol proteases, with residues at the equivalent structural positions that are incompatible with catalysis, and it cannot bind ubiquitin. It functions as a structural scaffold for intra- and intermolecular interactions in the complex.
messages: Cytoplasm
messages: Forms a heterotrimer with an asymmetric homodimer of the regulatory subunit PAN3 to form the poly(A)-nuclease (PAN) deadenylation complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Positively regulated by the regulatory subunit PAN3.
messages: The linker, or PAN3 interaction domain (PID), between the WD40 repeats and the pseudo-UCH domain mediates interaction with PAN3.

931890:Ecym 3484
gene id: 931890:Ecym_3484
uniprot id: G8JS48
names: Similarity
messages: Belongs to the FES1 family.

931890:Ecym 6228
gene id: 931890:Ecym_6228
uniprot id: G8JVD1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat WDR12/YTM1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 2485
gene id: 931890:Ecym_2485
uniprot id: G8JPV0
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2097
gene id: 931890:Ecym_2097
uniprot id: G8JPK1
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL9 family.

931890:Ecym 6300
gene id: 931890:Ecym_6300
uniprot id: G8JUA0
names: Similarity
messages: Belongs to the VPS26 family.

931890:Ecym 4643
gene id: 931890:Ecym_4643
uniprot id: G8JSE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family. BCS1 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 3463
gene id: 931890:Ecym_3463
uniprot id: G8JS27
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 1 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Nucleus

931890:Ecym 4084
gene id: 931890:Ecym_4084
uniprot id: G8JT10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPI19 family.
messages: Component of the phosphatidylinositol N-acetylglucosaminyltransferase (GPI-GlcNAc transferase) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

931890:Ecym 6115
gene id: 931890:Ecym_6115
uniprot id: G8JV29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

931890:Ecym 2482
gene id: 931890:Ecym_2482
uniprot id: G8JPU7
names: Similarity
messages: Belongs to the ZPR1 family.

931890:Ecym 7063
gene id: 931890:Ecym_7063
uniprot id: G8JVQ1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2575
gene id: 931890:Ecym_2575
uniprot id: G8JQF8
names: Cofactor
names: Similarity
messages: Belongs to the adenosylhomocysteinase family.
messages: Binds 1 NAD(+) per subunit.

931890:Ecym 2306
gene id: 931890:Ecym_2306
uniprot id: G8JQ46
names: Similarity
messages: Belongs to the actin family.

931890:Ecym 3339
gene id: 931890:Ecym_3339
uniprot id: G8JRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 1397
gene id: 931890:Ecym_1397
uniprot id: G8JM56
names: Similarity
messages: Belongs to the glycosyltransferase 34 family.

931890:Ecym 3146
gene id: 931890:Ecym_3146
uniprot id: G8JR80
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the deoxyhypusine hydroxylase family.
messages: Binds 2 Fe(2+) ions per subunit.
messages: Catalyzes the hydroxylation of the N(6)-(4-aminobutyl)-L-lysine intermediate to form hypusine, an essential post-translational modification only found in mature eIF-5A factor.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 7343
gene id: 931890:Ecym_7343
uniprot id: G8JWF8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFS-II family.
messages: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites.
messages: Nucleus

931890:Ecym 1075
gene id: 931890:Ecym_1075
uniprot id: G8JMC4
names: Similarity
messages: Belongs to the neutral sphingomyelinase family.

931890:Ecym 4504
gene id: 931890:Ecym_4504
uniprot id: G8JU38
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

931890:Ecym 4335
gene id: 931890:Ecym_4335
uniprot id: G8JTP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931890:Ecym 7155
gene id: 931890:Ecym_7155
uniprot id: G8JVY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIP1 family.
messages: Nucleus

931890:Ecym 5296
gene id: 931890:Ecym_5296
uniprot id: I6NDB6
names: Similarity
messages: Belongs to the UPF0045 family.

931890:Ecym 4639
gene id: 931890:Ecym_4639
uniprot id: G8JSE0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

931890:Ecym 6038
gene id: 931890:Ecym_6038
uniprot id: G8JUW3
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 4131
gene id: 931890:Ecym_4131
uniprot id: G8JT57
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 7284
gene id: 931890:Ecym_7284
uniprot id: G8JWA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 28 family.
messages: Endoplasmic reticulum
messages: Heterodimer with ALG14 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway.

931890:Ecym 1410
gene id: 931890:Ecym_1410
uniprot id: G8JM67
names: Similarity
messages: Belongs to the isochorismatase family.

931890:Ecym 4090
gene id: 931890:Ecym_4090
uniprot id: G8JT16
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.
messages: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
messages: Mitochondrion
messages: Nucleus

931890:Ecym 3579
gene id: 931890:Ecym_3579
uniprot id: G8JQR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OB-RGRP/VPS55 family.
messages: Membrane

931890:Ecym 8217
gene id: 931890:Ecym_8217
uniprot id: G8JXC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin light chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: coated pit

931890:Ecym 1003
gene id: 931890:Ecym_1003
uniprot id: G8JM03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MATALPHA1 family.
messages: Nucleus

931890:Ecym 4023
gene id: 931890:Ecym_4023
uniprot id: G8JSV3
names: Similarity
messages: Belongs to the pantothenate synthetase family.

931890:Ecym 2231
gene id: 931890:Ecym_2231
uniprot id: G8JP73
names: Similarity
messages: Belongs to the NAD kinase family.

931890:Ecym 2262
gene id: 931890:Ecym_2262
uniprot id: G8JPQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 5676
gene id: 931890:Ecym_5676
uniprot id: I6NEB4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931890:Ecym 6385
gene id: 931890:Ecym_6385
uniprot id: G8JUI0
names: Similarity
messages: Belongs to the actin family.

931890:Ecym 1181
gene id: 931890:Ecym_1181
uniprot id: G8JMW7
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

931890:Ecym 2265
gene id: 931890:Ecym_2265
uniprot id: G8JPQ6
names: Similarity
messages: Belongs to the ERT1/acuK family.

931890:Ecym 8369
gene id: 931890:Ecym_8369
uniprot id: G8JXR6
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

931890:Ecym 5361
gene id: 931890:Ecym_5361
uniprot id: I6NDH7
names: Similarity
messages: Belongs to the PP2C family.

931890:Ecym 5390
gene id: 931890:Ecym_5390
uniprot id: I6NDK3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the RNase HII family. Eukaryotic subfamily.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
messages: Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.

931890:Ecym 4339
gene id: 931890:Ecym_4339
uniprot id: G8JTP7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL34 family.

931890:Ecym 4413
gene id: 931890:Ecym_4413
uniprot id: G8JTW1
names: Similarity
messages: Belongs to the PPP phosphatase family. PP-5 (PP-T) subfamily.

931890:Ecym 5414
gene id: 931890:Ecym_5414
uniprot id: I6NDM6
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

931890:Ecym 3325
gene id: 931890:Ecym_3325
uniprot id: G8JRP6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

931890:Ecym 4363
gene id: 931890:Ecym_4363
uniprot id: G8JTR8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the F-actin-capping protein beta subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.
messages: cytoskeleton

931890:Ecym 4317
gene id: 931890:Ecym_4317
uniprot id: G8JTM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

931890:Ecym 8305
gene id: 931890:Ecym_8305
uniprot id: G8JXK9
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

931890:Ecym 5269
gene id: 931890:Ecym_5269
uniprot id: I6ND91
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRP38 family.
messages: Nucleus
messages: Required for pre-mRNA splicing.

931890:Ecym 2789
gene id: 931890:Ecym_2789
uniprot id: G8JQ24
names: Similarity
messages: Belongs to the VPS72/YL1 family.

931890:Ecym 2123
gene id: 931890:Ecym_2123
uniprot id: G8JPM7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS27 family.
messages: Endosome membrane
messages: Membrane

931890:Ecym 8019
gene id: 931890:Ecym_8019
uniprot id: G8JWU1
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
messages: Binds 1 FMN per subunit.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8014
gene id: 931890:Ecym_8014
uniprot id: G8JWT6
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6265
gene id: 931890:Ecym_6265
uniprot id: G8JVG8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS10 family.

931890:Ecym 8313
gene id: 931890:Ecym_8313
uniprot id: G8JXL7
names: Similarity
messages: Belongs to the archaeal Rpo10/eukaryotic RPB10 RNA polymerase subunit family.

931890:Ecym 7404
gene id: 931890:Ecym_7404
uniprot id: G8JWL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLD2 family.
messages: Has a role in the initiation of DNA replication. Required at S-phase checkpoint.
messages: Nucleus

931890:Ecym 1520
gene id: 931890:Ecym_1520
uniprot id: G8JMS7
names: Function
names: Similarity
messages: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
messages: Belongs to the actin family.

931890:Ecym 8201
gene id: 931890:Ecym_8201
uniprot id: G8JXB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S1C family.
messages: Nuclear serine protease which mediates apoptosis.
messages: Nucleus

931890:Ecym 6193
gene id: 931890:Ecym_6193
uniprot id: G8JV97
names: Similarity
messages: Belongs to the DNA repair enzymes AP/ExoA family.

931890:Ecym 2402
gene id: 931890:Ecym_2402
uniprot id: G8JNR7
names: Similarity
messages: Belongs to the pseudouridine synthase TruD family.

931890:Ecym 2194
gene id: 931890:Ecym_2194
uniprot id: G8JP38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. Aurora subfamily.
messages: kinetochore
messages: spindle

931890:Ecym 4173
gene id: 931890:Ecym_4173
uniprot id: G8JT97
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

931890:Ecym 3009
gene id: 931890:Ecym_3009
uniprot id: G8JQV9
names: Similarity
messages: Belongs to the MYBBP1A family.

931890:Ecym 5371
gene id: 931890:Ecym_5371
uniprot id: I6NDI5
names: Similarity
messages: Belongs to the XPG/RAD2 endonuclease family.

931890:Ecym 2244
gene id: 931890:Ecym_2244
uniprot id: G8JPN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

931890:Ecym 4054
gene id: 931890:Ecym_4054
uniprot id: G8JSY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ING family.
messages: Nucleus

931890:Ecym 5114
gene id: 931890:Ecym_5114
uniprot id: I6NCV2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

931890:Ecym 2794
gene id: 931890:Ecym_2794
uniprot id: G8JQ29
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1387
gene id: 931890:Ecym_1387
uniprot id: G8JM47
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

931890:Ecym 5489
gene id: 931890:Ecym_5489
uniprot id: I6NDU2
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

931890:Ecym 5083
gene id: 931890:Ecym_5083
uniprot id: I6NCT0
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

931890:Ecym 2763
gene id: 931890:Ecym_2763
uniprot id: G8JPZ9
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 5440
gene id: 931890:Ecym_5440
uniprot id: I6NDQ0
names: Function
names: Similarity
messages: Belongs to the CKS family.
messages: Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function.

931890:Ecym 1451
gene id: 931890:Ecym_1451
uniprot id: G8JMG0
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2154
gene id: 931890:Ecym_2154
uniprot id: G8JNJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

931890:Ecym 4045
gene id: 931890:Ecym_4045
uniprot id: G8JSX3
names: Similarity
messages: Belongs to the nucleoporin Nup133 family.

931890:Ecym 2543
gene id: 931890:Ecym_2543
uniprot id: G8JQA5
names: Function
names: Similarity
messages: Belongs to the VPS16 family.
messages: Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.

931890:Ecym 4168
gene id: 931890:Ecym_4168
uniprot id: G8JT92
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARV1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes.
messages: Membrane
messages: Regulates also the sphingolipid metabolism.

931890:Ecym 4127
gene id: 931890:Ecym_4127
uniprot id: G8JT53
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK2 subfamily.
messages: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Mitochondrion intermembrane space
messages: Monomer.
messages: cytosol

931890:Ecym 8167
gene id: 931890:Ecym_8167
uniprot id: G8JX79
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8169
gene id: 931890:Ecym_8169
uniprot id: G8JX81
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 6091
gene id: 931890:Ecym_6091
uniprot id: G8JV08
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome b560 family.
messages: Membrane

931890:Ecym 2292
gene id: 931890:Ecym_2292
uniprot id: G8JQ32
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7397
gene id: 931890:Ecym_7397
uniprot id: G8JWK8
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.

931890:Ecym 1083
gene id: 931890:Ecym_1083
uniprot id: G8JMD1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4170
gene id: 931890:Ecym_4170
uniprot id: G8JT94
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

931890:Ecym 3506
gene id: 931890:Ecym_3506
uniprot id: G8JS65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDE1 family.
messages: Membrane

931890:Ecym 2188
gene id: 931890:Ecym_2188
uniprot id: G8JP32
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic GTase family.
messages: Heterodimer.
messages: Nucleus
messages: Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate.

931890:Ecym 2648
gene id: 931890:Ecym_2648
uniprot id: G8JNT4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family. DEGS subfamily.
messages: Membrane

931890:Ecym 6426
gene id: 931890:Ecym_6426
uniprot id: G8JUL8
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

931890:Ecym 6016
gene id: 931890:Ecym_6016
uniprot id: G8JUU5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the squalene monooxygenase family.
messages: Catalyzes the stereospecific oxidation of squalene to (S)-2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis.
messages: Endoplasmic reticulum membrane
messages: Microsome membrane

931890:Ecym 4574
gene id: 931890:Ecym_4574
uniprot id: G8JS85
names: Similarity
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.

931890:Ecym 2052
gene id: 931890:Ecym_2052
uniprot id: G8JP09
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS19 family.

931890:Ecym 6286
gene id: 931890:Ecym_6286
uniprot id: G8JVI7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS).
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 8254
gene id: 931890:Ecym_8254
uniprot id: G8JXG3
names: Similarity
messages: Belongs to the NOP9 family.

931890:Ecym 3519
gene id: 931890:Ecym_3519
uniprot id: G8JQL3
names: Function
names: Similarity
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).

931890:Ecym 3522
gene id: 931890:Ecym_3522
uniprot id: G8JQL6
names: Activity Regulation
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.

931890:Ecym 3143
gene id: 931890:Ecym_3143
uniprot id: G8JR77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC3 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER).

931890:Ecym 3021
gene id: 931890:Ecym_3021
uniprot id: G8JQW9
names: Similarity
messages: Belongs to the NPR2 family.

931890:Ecym 8350
gene id: 931890:Ecym_8350
uniprot id: G8JXP9
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

931890:Ecym 4378
gene id: 931890:Ecym_4378
uniprot id: G8JTT0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

931890:Ecym 4418
gene id: 931890:Ecym_4418
uniprot id: G8JTW5
names: Similarity
messages: Belongs to the TEL2 family.

931890:Ecym 4311
gene id: 931890:Ecym_4311
uniprot id: G8JTM1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC4 subfamily.
messages: Nucleus

931890:Ecym 2433
gene id: 931890:Ecym_2433
uniprot id: G8JPA5
names: Similarity
messages: Belongs to the CENP-C/MIF2 family.

931890:Ecym 3578
gene id: 931890:Ecym_3578
uniprot id: G8JQR4
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 5558
gene id: 931890:Ecym_5558
uniprot id: I6NE06
names: Similarity
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.

931890:Ecym 1318
gene id: 931890:Ecym_1318
uniprot id: G8JN89
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 5379
gene id: 931890:Ecym_5379
uniprot id: I6NDJ2
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

931890:Ecym 7471
gene id: 931890:Ecym_7471
uniprot id: G8JWS4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS4 family.

931890:Ecym 2353
gene id: 931890:Ecym_2353
uniprot id: G8JNL9
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.

931890:Ecym 6180
gene id: 931890:Ecym_6180
uniprot id: G8JV84
names: Similarity
messages: Belongs to the EF-1-beta/EF-1-delta family.

931890:Ecym 4416
gene id: 931890:Ecym_4416
uniprot id: G8JTW4
names: Function
names: Similarity
messages: Belongs to the RRG8 family.
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

931890:Ecym 1078
gene id: 931890:Ecym_1078
uniprot id: G8JMC7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2777
gene id: 931890:Ecym_2777
uniprot id: G8JQ13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecY/SEC61-alpha family.
messages: Membrane

931890:Ecym 5282
gene id: 931890:Ecym_5282
uniprot id: I6NDA2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUF2 family.
messages: Nucleus
messages: kinetochore

931890:Ecym 5506
gene id: 931890:Ecym_5506
uniprot id: I6NDV7
names: Subcellular Location Annotation
messages: Golgi apparatus

931890:Ecym 3126
gene id: 931890:Ecym_3126
uniprot id: G8JR61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIT family.
messages: Cytoplasm

931890:Ecym 5593
gene id: 931890:Ecym_5593
uniprot id: I6NE38
names: Similarity
messages: Belongs to the GroES chaperonin family.

931890:Ecym 1245
gene id: 931890:Ecym_1245
uniprot id: G8JN25
names: Similarity
messages: Belongs to the CBF/MAK21 family.

931890:Ecym 6432
gene id: 931890:Ecym_6432
uniprot id: G8JUM3
names: Similarity
messages: Belongs to the importin alpha family.

931890:Ecym 7201
gene id: 931890:Ecym_7201
uniprot id: G8JW34
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

931890:Ecym 2800
gene id: 931890:Ecym_2800
uniprot id: G8JQD4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RMT2 methyltransferase family.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-arginine N-methyltransferase that methylates the delta-nitrogen atom of arginine residues to form N5-methylarginine (type IV) in target proteins. Monomethylates ribosomal protein L12.

931890:Ecym 2115
gene id: 931890:Ecym_2115
uniprot id: G8JPL9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP1 family.
messages: Membrane
messages: Peroxisome membrane
messages: Required for peroxisome inheritance.

931890:Ecym 3508
gene id: 931890:Ecym_3508
uniprot id: G8JS67
names: Similarity
messages: Belongs to the peptidase M24 family.

931890:Ecym 7254
gene id: 931890:Ecym_7254
uniprot id: G8JW83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP18 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

931890:Ecym 4785
gene id: 931890:Ecym_4785
uniprot id: G8JSS4
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

931890:Ecym 7047
gene id: 931890:Ecym_7047
uniprot id: G8JVN8
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

931890:Ecym 1022
gene id: 931890:Ecym_1022
uniprot id: G8JM21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UQCRB/QCR7 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Mitochondrion inner membrane

931890:Ecym 3460
gene id: 931890:Ecym_3460
uniprot id: G8JS25
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ENY2 family.
messages: Component of the nuclear pore complex (NPC)-associated TREX-2 complex (transcription and export complex 2), composed of at least SUS1, SAC3, THP1, SEM1, and CDC31. TREX-2 contains 2 SUS1 chains. The TREX-2 complex interacts with the nucleoporin NUP1. Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with THP1, SAC3, SGF11, and with the RNA polymerase II.
messages: Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex required for deubiquitination of H2B and for the maintenance of steady-state H3 methylation levels. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. May also be involved in cytoplasmic mRNA decay by interaction with components of P-bodies.
messages: P-body
messages: nucleoplasm

931890:Ecym 2055
gene id: 931890:Ecym_2055
uniprot id: G8JP12
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx5 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.

931890:Ecym 4481
gene id: 931890:Ecym_4481
uniprot id: G8JU18
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the mannose-6-phosphate isomerase type 1 family.
messages: Binds 1 zinc ion per subunit.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

931890:Ecym 7356
gene id: 931890:Ecym_7356
uniprot id: G8JWG9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

931890:Ecym 6156
gene id: 931890:Ecym_6156
uniprot id: G8JV67
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

931890:Ecym 8131
gene id: 931890:Ecym_8131
uniprot id: G8JX48
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

931890:Ecym 6056
gene id: 931890:Ecym_6056
uniprot id: G8JUY0
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

931890:Ecym 5663
gene id: 931890:Ecym_5663
uniprot id: I6NEA4
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 7184
gene id: 931890:Ecym_7184
uniprot id: G8JW17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNAP family.
messages: Membrane
messages: Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus.

931890:Ecym 4539
gene id: 931890:Ecym_4539
uniprot id: G8JU72
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

931890:Ecym 3152
gene id: 931890:Ecym_3152
uniprot id: G8JR86
names: Similarity
messages: Belongs to the PI3/PI4-kinase family.

931890:Ecym 4456
gene id: 931890:Ecym_4456
uniprot id: G8JTZ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 2399
gene id: 931890:Ecym_2399
uniprot id: G8JNR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 1215
gene id: 931890:Ecym_1215
uniprot id: G8JMZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

931890:Ecym 7111
gene id: 931890:Ecym_7111
uniprot id: G8JVU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5310
gene id: 931890:Ecym_5310
uniprot id: I6NDC9
names: Similarity
messages: Belongs to the TrpF family.

931890:Ecym 1385
gene id: 931890:Ecym_1385
uniprot id: G8JM45
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

931890:Ecym 2192
gene id: 931890:Ecym_2192
uniprot id: G8JP36
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP72 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER).
messages: Cytoplasm

931890:Ecym 2613
gene id: 931890:Ecym_2613
uniprot id: G8JQJ3
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel.

931890:Ecym 3347
gene id: 931890:Ecym_3347
uniprot id: G8JRR6
names: Similarity
messages: Belongs to the frataxin family.

931890:Ecym 7065
gene id: 931890:Ecym_7065
uniprot id: G8JVQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC62 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7202
gene id: 931890:Ecym_7202
uniprot id: G8JW35
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7013
gene id: 931890:Ecym_7013
uniprot id: G8JVK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DPH1/DPH2 family. DPH2 subfamily.
messages: Cytoplasm
messages: Required for the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2. DPH1 and DPH2 transfer a 3-amino-3-carboxypropyl (ACP) group from S-adenosyl-L-methionine (SAM) to a histidine residue, the reaction is assisted by a reduction system comprising DPH3 and a NADH-dependent reductase. Facilitates the reduction of the catalytic iron-sulfur cluster found in the DPH1 subunit.

931890:Ecym 1046
gene id: 931890:Ecym_1046
uniprot id: G8JM44
names: Cofactor
names: Similarity
messages: Belongs to the MsrB Met sulfoxide reductase family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 2140
gene id: 931890:Ecym_2140
uniprot id: G8JNH6
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

931890:Ecym 1219
gene id: 931890:Ecym_1219
uniprot id: G8JN02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

931890:Ecym 3250
gene id: 931890:Ecym_3250
uniprot id: G8JRH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BRE1 family.
messages: Nucleus

931890:Ecym 8237
gene id: 931890:Ecym_8237
uniprot id: G8JXE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DPM2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization.

931890:Ecym 4296
gene id: 931890:Ecym_4296
uniprot id: G8JTK6
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.

931890:Ecym 7090
gene id: 931890:Ecym_7090
uniprot id: G8JVS7
names: Similarity
messages: Belongs to the prephenate/arogenate dehydrogenase family.

931890:Ecym 8276
gene id: 931890:Ecym_8276
uniprot id: G8JXI4
names: Subunit
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

931890:Ecym 1455
gene id: 931890:Ecym_1455
uniprot id: G8JMG4
names: Cofactor
names: Miscellaneous
names: Similarity
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: The active site is a redox-active disulfide bond.

931890:Ecym 5259
gene id: 931890:Ecym_5259
uniprot id: I6ND83
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family.
messages: Membrane

931890:Ecym 4342
gene id: 931890:Ecym_4342
uniprot id: G8JTQ0
names: Function
names: Similarity
messages: Belongs to the ATP phosphoribosyltransferase family.
messages: Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of the enzymatic activity.

931890:Ecym 5582
gene id: 931890:Ecym_5582
uniprot id: I6NE28
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 6233
gene id: 931890:Ecym_6233
uniprot id: G8JVD6
names: Similarity
messages: Belongs to the EFR3 family.

931890:Ecym 1425
gene id: 931890:Ecym_1425
uniprot id: G8JM82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CGR1 family.
messages: Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit.
messages: nucleolus

931890:Ecym 3324
gene id: 931890:Ecym_3324
uniprot id: G8JRP5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD type 2 subfamily.
messages: Nucleus
messages: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.

931890:Ecym 3033
gene id: 931890:Ecym_3033
uniprot id: G8JQX9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5239
gene id: 931890:Ecym_5239
uniprot id: I6ND64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes medium subunit family.
messages: Membrane

931890:Ecym 4236
gene id: 931890:Ecym_4236
uniprot id: G8JTF0
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 1514
gene id: 931890:Ecym_1514
uniprot id: G8JMS2
names: Function
names: Similarity
messages: Belongs to the phage and mitochondrial RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

931890:Ecym 1369
gene id: 931890:Ecym_1369
uniprot id: G8JND8
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 3208
gene id: 931890:Ecym_3208
uniprot id: G8JRD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7431
gene id: 931890:Ecym_7431
uniprot id: G8JWN7
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 2031
gene id: 931890:Ecym_2031
uniprot id: G8JNZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP11 family.
messages: Mitochondrion

931890:Ecym 2006
gene id: 931890:Ecym_2006
uniprot id: G8JNF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS3/PSF3 family.
messages: Component of the GINS complex which is a heterotetramer of SLD5, PSF1, PSF2 and PSF3.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

931890:Ecym 5347
gene id: 931890:Ecym_5347
uniprot id: I6NDG4
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

931890:Ecym 3209
gene id: 931890:Ecym_3209
uniprot id: G8JRD8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 21 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 2122
gene id: 931890:Ecym_2122
uniprot id: G8JPM6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5405
gene id: 931890:Ecym_5405
uniprot id: I6NDL8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MET18/MMS19 family.
messages: Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins.
messages: Nucleus

931890:Ecym 2093
gene id: 931890:Ecym_2093
uniprot id: G8JPJ7
names: Similarity
messages: Belongs to the WD repeat PWP2 family.

931890:Ecym 7456
gene id: 931890:Ecym_7456
uniprot id: G8JWR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG11 family.
messages: Homodimer.
messages: Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Vacuole membrane

931890:Ecym 5555
gene id: 931890:Ecym_5555
uniprot id: I6NE03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

931890:Ecym 5214
gene id: 931890:Ecym_5214
uniprot id: I6ND41
names: Similarity
messages: Belongs to the acyl-CoA dehydrogenase family.

931890:Ecym 3512
gene id: 931890:Ecym_3512
uniprot id: G8JS71
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6274
gene id: 931890:Ecym_6274
uniprot id: G8JVH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL41 family.
messages: Mitochondrion

931890:Ecym 8078
gene id: 931890:Ecym_8078
uniprot id: G8JX00
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG9 family.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Phospholipid scramblase involved in autophagy. Cycles between the preautophagosomal structure/phagophore assembly site (PAS) and the cytoplasmic vesicle pool and supplies membrane for the growing autophagosome. Lipid scramblase activity plays a key role in preautophagosomal structure/phagophore assembly by distributing the phospholipids that arrive through ATG2 from the cytoplasmic to the luminal leaflet of the bilayer, thereby driving autophagosomal membrane expansion.
messages: Preautophagosomal structure membrane

931890:Ecym 4357
gene id: 931890:Ecym_4357
uniprot id: G8JTR4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7147
gene id: 931890:Ecym_7147
uniprot id: G8JVY1
names: Function
names: Subcellular Location Annotation
messages: Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7416
gene id: 931890:Ecym_7416
uniprot id: G8JWM6
names: Similarity
messages: Belongs to the p23/wos2 family.

931890:Ecym 2490
gene id: 931890:Ecym_2490
uniprot id: G8JPV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD18 family.
messages: E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme UBC2/RAD6 to form the UBC2-RAD18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA.
messages: Interacts with E2 UBC2, forming a complex with ubiquitin ligase activity.
messages: Nucleus

931890:Ecym 2060
gene id: 931890:Ecym_2060
uniprot id: G8JP17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA11 family.
messages: Cytoplasm

931890:Ecym 3572
gene id: 931890:Ecym_3572
uniprot id: G8JQQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RAD23 family.
messages: Cytoplasm
messages: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.
messages: Nucleus

931890:Ecym 3195
gene id: 931890:Ecym_3195
uniprot id: G8JRC4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.
messages: Membrane

931890:Ecym 2660
gene id: 931890:Ecym_2660
uniprot id: G8JNU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. TRM7 subfamily.
messages: Cytoplasm
messages: Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs.

931890:Ecym 4144
gene id: 931890:Ecym_4144
uniprot id: G8JT69
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1285
gene id: 931890:Ecym_1285
uniprot id: G8JN60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family. Pelota subfamily.
messages: Cytoplasm
messages: May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non-functional ribosomes and degrade damaged mRNAs.

931890:Ecym 5299
gene id: 931890:Ecym_5299
uniprot id: I6NDB9
names: Similarity
messages: Belongs to the UPP synthase family.

931890:Ecym 4559
gene id: 931890:Ecym_4559
uniprot id: G8JU90
names: Similarity
messages: Belongs to the TRIAP1/MDM35 family.

931890:Ecym 7455
gene id: 931890:Ecym_7455
uniprot id: G8JWQ9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NADPH-dependent diflavin oxidoreductase NDOR1 family.
messages: Cytoplasm
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Interacts with DRE2; as part of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: NADPH-dependent reductase which is a central component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Transfers electrons from NADPH via its FAD and FMN prosthetic groups to the [2Fe-2S] cluster of DRE2, another key component of the CIA machinery. In turn, this reduced cluster provides electrons for assembly of cytosolic iron-sulfur cluster proteins. Positively controls H(2)O(2)-induced cell death.

931890:Ecym 6468
gene id: 931890:Ecym_6468
uniprot id: G8JUQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 4114
gene id: 931890:Ecym_4114
uniprot id: G8JT40
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 4652
gene id: 931890:Ecym_4652
uniprot id: G8JSF2
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

931890:Ecym 4155
gene id: 931890:Ecym_4155
uniprot id: G8JT79
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily.
messages: Endoplasmic reticulum membrane
messages: Functions as a zinc transporter.
messages: Membrane

931890:Ecym 4234
gene id: 931890:Ecym_4234
uniprot id: G8JTE8
names: Similarity
names: Subunit
messages: Belongs to the aspartate-semialdehyde dehydrogenase family.
messages: Homodimer.

931890:Ecym 4334
gene id: 931890:Ecym_4334
uniprot id: G8JTP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the steroid 5-alpha reductase family. Polyprenol reductase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism.

931890:Ecym 5499
gene id: 931890:Ecym_5499
uniprot id: I6NDV0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 2804
gene id: 931890:Ecym_2804
uniprot id: G8JQD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Membrane

931890:Ecym 2369
gene id: 931890:Ecym_2369
uniprot id: G8JNN4
names: Function
messages: Catalytic subunit in the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

931890:Ecym 8259
gene id: 931890:Ecym_8259
uniprot id: G8JXG7
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.
messages: Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to cysteines occuring in specific C-terminal amino acid sequences.

931890:Ecym 8331
gene id: 931890:Ecym_8331
uniprot id: G8JXN5
names: Similarity
messages: Belongs to the eukaryotic RPB8 RNA polymerase subunit family.

931890:Ecym 1212
gene id: 931890:Ecym_1212
uniprot id: G8JMZ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the clathrin heavy chain family.
messages: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.
messages: Cytoplasmic vesicle membrane
messages: Membrane
messages: coated pit

931890:Ecym 5547
gene id: 931890:Ecym_5547
uniprot id: I6NDZ5
names: Similarity
messages: Belongs to the PPP phosphatase family.

931890:Ecym 7229
gene id: 931890:Ecym_7229
uniprot id: G8JW60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

931890:Ecym 4259
gene id: 931890:Ecym_4259
uniprot id: G8JTH0
names: Similarity
messages: Belongs to the 2-oxoacid dehydrogenase family.

931890:Ecym 2103
gene id: 931890:Ecym_2103
uniprot id: G8JPK7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL19 family.

931890:Ecym 3182
gene id: 931890:Ecym_3182
uniprot id: G8JRB2
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase G subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

931890:Ecym 2024
gene id: 931890:Ecym_2024
uniprot id: G8JNY3
names: Similarity
messages: Belongs to the WD repeat RTC1 family.

931890:Ecym 4025
gene id: 931890:Ecym_4025
uniprot id: G8JSV5
names: Similarity
messages: Belongs to the helicase family. RAD25/XPB subfamily.

931890:Ecym 1064
gene id: 931890:Ecym_1064
uniprot id: G8JMB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTA1 family.
messages: Cytoplasm
messages: Endosome membrane
messages: Membrane

931890:Ecym 1031
gene id: 931890:Ecym_1031
uniprot id: G8JM29
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

931890:Ecym 2384
gene id: 931890:Ecym_2384
uniprot id: G8JNP9
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

931890:Ecym 8342
gene id: 931890:Ecym_8342
uniprot id: G8JXP5
names: Subcellular Location Annotation
messages: nuclear pore complex

931890:Ecym 4478
gene id: 931890:Ecym_4478
uniprot id: G8JU15
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

931890:Ecym 8164
gene id: 931890:Ecym_8164
uniprot id: G8JX77
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4414
gene id: 931890:Ecym_4414
uniprot id: G8JTW2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4706
gene id: 931890:Ecym_4706
uniprot id: G8JSK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC61-beta family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Necessary for protein translocation in the endoplasmic reticulum.

931890:Ecym 5518
gene id: 931890:Ecym_5518
uniprot id: I6NDW8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCP1 family.
messages: Involved in nuclear export, actin cytoskeleton organization and vesicular transport.
messages: Nucleus

931890:Ecym 4421
gene id: 931890:Ecym_4421
uniprot id: G8JTW7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Required for proper protein synthesis within the mitochondrion.
messages: Belongs to the GatF family.
messages: Mitochondrion inner membrane
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

931890:Ecym 4523
gene id: 931890:Ecym_4523
uniprot id: G8JU57
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

931890:Ecym 4678
gene id: 931890:Ecym_4678
uniprot id: G8JSH7
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 3480
gene id: 931890:Ecym_3480
uniprot id: G8JS44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB4 family.
messages: Component of the 7-subunit TFIIH core complex composed of XPB/SSL2, XPD/RAD3, SSL1, TFB1, TFB2, TFB4 and TFB5, which is active in NER. The core complex associates with the 3-subunit CTD-kinase module TFIIK composed of CCL1, KIN28 and TFB3 to form the 10-subunit holoenzyme (holo-TFIIH) active in transcription.
messages: Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module TFIIK controls the initiation of transcription.
messages: Nucleus

931890:Ecym 6337
gene id: 931890:Ecym_6337
uniprot id: G8JUD3
names: Similarity
messages: Belongs to the TRL1 family.

931890:Ecym 4174
gene id: 931890:Ecym_4174
uniprot id: G8JT98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

931890:Ecym 5127
gene id: 931890:Ecym_5127
uniprot id: I6NCW4
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

931890:Ecym 5102
gene id: 931890:Ecym_5102
uniprot id: I6NCU3
names: Similarity
messages: Belongs to the enolase family.

931890:Ecym 2500
gene id: 931890:Ecym_2500
uniprot id: G8JPW4
names: Similarity
messages: Belongs to the PPP phosphatase family.

931890:Ecym 8132
gene id: 931890:Ecym_8132
uniprot id: G8JX49
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

931890:Ecym 8414
gene id: 931890:Ecym_8414
uniprot id: G8JXV9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5252
gene id: 931890:Ecym_5252
uniprot id: I6ND76
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 5246
gene id: 931890:Ecym_5246
uniprot id: I6ND71
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

931890:Ecym 1304
gene id: 931890:Ecym_1304
uniprot id: G8JN78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bacterial ribosomal protein bL27 family.
messages: Mitochondrion

931890:Ecym 6096
gene id: 931890:Ecym_6096
uniprot id: G8JV13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

931890:Ecym 2181
gene id: 931890:Ecym_2181
uniprot id: G8JP26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Arf family.
messages: Belongs to the small GTPase superfamily. SAR1 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane

931890:Ecym 2445
gene id: 931890:Ecym_2445
uniprot id: G8JPB6
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS6 family.

931890:Ecym 5510
gene id: 931890:Ecym_5510
uniprot id: I6NDW1
names: Cofactor
names: Similarity
names: Subunit
messages: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Homodimer.

931890:Ecym 3162
gene id: 931890:Ecym_3162
uniprot id: G8JR96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adaptor complexes small subunit family.
messages: Cell membrane
messages: Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: coated pit

931890:Ecym 3621
gene id: 931890:Ecym_3621
uniprot id: G8JQU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2752
gene id: 931890:Ecym_2752
uniprot id: G8JPY8
names: Similarity
messages: Belongs to the PHP hydrolase family. HisK subfamily.

931890:Ecym 1141
gene id: 931890:Ecym_1141
uniprot id: G8JMN8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase V0D/AC39 subunit family.
messages: Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments. This subunit is a non-integral membrane component of the membrane pore domain and is required for proper assembly of the V0 sector. Might be involved in the regulated assembly of V1 subunits onto the membrane sector or alternatively may prevent the passage of protons through V0 pores.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

931890:Ecym 3570
gene id: 931890:Ecym_3570
uniprot id: G8JQQ6
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c family.
messages: Binds 1 heme group per subunit.
messages: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.
messages: Mitochondrion intermembrane space

931890:Ecym 6099
gene id: 931890:Ecym_6099
uniprot id: G8JV16
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

931890:Ecym 5157
gene id: 931890:Ecym_5157
uniprot id: I6NCZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RIX1/PELP1 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA and the nucleoplasmic transit of the pre-60S ribosomal subunits. Regulates pre-60S association of the critical remodeling factor MDN1.
messages: Nucleus

931890:Ecym 3464
gene id: 931890:Ecym_3464
uniprot id: G8JS28
names: Similarity
messages: Belongs to the spermidine/spermine synthase family.

931890:Ecym 6123
gene id: 931890:Ecym_6123
uniprot id: G8JV37
names: Similarity
messages: Belongs to the YIP1 family.

931890:Ecym 7191
gene id: 931890:Ecym_7191
uniprot id: G8JW24
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2303
gene id: 931890:Ecym_2303
uniprot id: G8JQ43
names: Function
names: Similarity
messages: Belongs to the MPI phosphatase family.
messages: Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle.

931890:Ecym 2778
gene id: 931890:Ecym_2778
uniprot id: G8JQ14
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 85 family.
messages: cytosol

931890:Ecym 1089
gene id: 931890:Ecym_1089
uniprot id: G8JMD7
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

931890:Ecym 5275
gene id: 931890:Ecym_5275
uniprot id: I6ND96
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NPC2 family.
messages: Catalyzes the intermembrane transfer of phosphatidylglycerol and phosphatidylinositol.
messages: Monomer.

931890:Ecym 8298
gene id: 931890:Ecym_8298
uniprot id: G8JXK3
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 2678
gene id: 931890:Ecym_2678
uniprot id: G8JNW3
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5325
gene id: 931890:Ecym_5325
uniprot id: I6NDE2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BMT2 family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that specifically methylates the N(1) position of an adenine present in helix 65 in 25S rRNA.
messages: nucleolus

931890:Ecym 1043
gene id: 931890:Ecym_1043
uniprot id: G8JM41
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2378
gene id: 931890:Ecym_2378
uniprot id: G8JNP3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

931890:Ecym 3032
gene id: 931890:Ecym_3032
uniprot id: G8JQX8
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 2273
gene id: 931890:Ecym_2273
uniprot id: G8JPR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSA1 family.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

931890:Ecym 3455
gene id: 931890:Ecym_3455
uniprot id: G8JS20
names: Similarity
messages: Belongs to the low molecular weight phosphotyrosine protein phosphatase family.

931890:Ecym 4341
gene id: 931890:Ecym_4341
uniprot id: G8JTP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SYG1 (TC 2.A.94) family.
messages: Membrane

931890:Ecym 6211
gene id: 931890:Ecym_6211
uniprot id: G8JVB4
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit B family.

931890:Ecym 4674
gene id: 931890:Ecym_4674
uniprot id: G8JSH3
names: Similarity
messages: Belongs to the non-repetitive/WGA-negative nucleoporin family.

931890:Ecym 3603
gene id: 931890:Ecym_3603
uniprot id: G8JQT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931890:Ecym 5619
gene id: 931890:Ecym_5619
uniprot id: I6NE63
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

931890:Ecym 3193
gene id: 931890:Ecym_3193
uniprot id: G8JRC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AATF family.
messages: nucleolus

931890:Ecym 3329
gene id: 931890:Ecym_3329
uniprot id: G8JRQ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS23 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Mitochondrion

931890:Ecym 1029
gene id: 931890:Ecym_1029
uniprot id: G8JM27
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: GTPase-activating protein for the ADP ribosylation factor family.

931890:Ecym 6197
gene id: 931890:Ecym_6197
uniprot id: G8JVA1
names: Similarity
messages: Belongs to the acetyl-CoA hydrolase/transferase family.

931890:Ecym 7288
gene id: 931890:Ecym_7288
uniprot id: G8JWB1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPR3 family.
messages: Mediates inactivation of the TORC1 complex in response to amino acid starvation. Required for meiotic nuclear division.
messages: Vacuole membrane

931890:Ecym 2435
gene id: 931890:Ecym_2435
uniprot id: G8JPA7
names: Similarity
messages: Belongs to the UPL family. K-HECT subfamily.

931890:Ecym 6129
gene id: 931890:Ecym_6129
uniprot id: G8JV42
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL50 family.
messages: Mitochondrion

931890:Ecym 2689
gene id: 931890:Ecym_2689
uniprot id: G8JPD1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1298
gene id: 931890:Ecym_1298
uniprot id: G8JN72
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 4205
gene id: 931890:Ecym_4205
uniprot id: G8JTB9
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

931890:Ecym 7038
gene id: 931890:Ecym_7038
uniprot id: G8JVM9
names: Similarity
messages: Belongs to the WD repeat TAF5 family.

931890:Ecym 2637
gene id: 931890:Ecym_2637
uniprot id: G8JNS4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Nth/MutY family.
messages: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.
messages: Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand.
messages: Mitochondrion
messages: Nucleus

931890:Ecym 2069
gene id: 931890:Ecym_2069
uniprot id: G8JPH7
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

931890:Ecym 7258
gene id: 931890:Ecym_7258
uniprot id: G8JW87
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5568
gene id: 931890:Ecym_5568
uniprot id: I6NE14
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase beta subunit family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.

931890:Ecym 2739
gene id: 931890:Ecym_2739
uniprot id: G8JPH2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

931890:Ecym 5581
gene id: 931890:Ecym_5581
uniprot id: I6NE27
names: Similarity
messages: Belongs to the ClpA/ClpB family.

931890:Ecym 5303
gene id: 931890:Ecym_5303
uniprot id: I6NDC3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931890:Ecym 1406
gene id: 931890:Ecym_1406
uniprot id: G8JM64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL40 family.
messages: Mitochondrion

931890:Ecym 1291
gene id: 931890:Ecym_1291
uniprot id: G8JN66
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

931890:Ecym 3018
gene id: 931890:Ecym_3018
uniprot id: G8JQW6
names: Similarity
messages: Belongs to the peptidase S8 family.

931890:Ecym 4711
gene id: 931890:Ecym_4711
uniprot id: G8JSK9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit J family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

931890:Ecym 7361
gene id: 931890:Ecym_7361
uniprot id: G8JWH3
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

931890:Ecym 1239
gene id: 931890:Ecym_1239
uniprot id: G8JN21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SYF2 family.
messages: Involved in pre-mRNA splicing.
messages: May be part of a spliceosome complex.
messages: Nucleus

931890:Ecym 5605
gene id: 931890:Ecym_5605
uniprot id: I6NE49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family.
messages: Mitochondrion inner membrane

931890:Ecym 1524
gene id: 931890:Ecym_1524
uniprot id: G8JMT0
names: Similarity
messages: Belongs to the FYV7 family.

931890:Ecym 1154
gene id: 931890:Ecym_1154
uniprot id: G8JMQ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC1 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Nucleus
messages: ORC is composed of six subunits.

931890:Ecym 7062
gene id: 931890:Ecym_7062
uniprot id: G8JVQ0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
messages: Binds 1 FAD per subunit.
messages: Cytoplasm
messages: Maintains high levels of reduced glutathione in the cytosol.

931890:Ecym 2547
gene id: 931890:Ecym_2547
uniprot id: G8JQA9
names: Function
names: Similarity
messages: Belongs to the catalase family.
messages: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.

931890:Ecym 3316
gene id: 931890:Ecym_3316
uniprot id: G8JRN8
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

931890:Ecym 8391
gene id: 931890:Ecym_8391
uniprot id: G8JXT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRG family.
messages: Nucleus

931890:Ecym 4207
gene id: 931890:Ecym_4207
uniprot id: G8JTC1
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

931890:Ecym 1265
gene id: 931890:Ecym_1265
uniprot id: G8JN43
names: Similarity
messages: Belongs to the eukaryotic-type primase small subunit family.

931890:Ecym 3186
gene id: 931890:Ecym_3186
uniprot id: G8JRB6
names: Similarity
messages: Belongs to the RNR ribonuclease family.

931890:Ecym 3117
gene id: 931890:Ecym_3117
uniprot id: G8JR54
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

931890:Ecym 5509
gene id: 931890:Ecym_5509
uniprot id: I6NDW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPT35 family.
messages: Endosome membrane
messages: Recruits the lipid transfer protein VPS13 to endosomal and vacuolar membranes.
messages: Vacuole membrane

931890:Ecym 4770
gene id: 931890:Ecym_4770
uniprot id: G8JSR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOT1 family.
messages: Golgi apparatus membrane
messages: Membrane

931890:Ecym 4502
gene id: 931890:Ecym_4502
uniprot id: G8JU36
names: Similarity
names: Subunit
messages: Belongs to the ATPase gamma chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.

931890:Ecym 2117
gene id: 931890:Ecym_2117
uniprot id: G8JPM1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 9 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 4214
gene id: 931890:Ecym_4214
uniprot id: G8JTC8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF10 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation), facilitation of DNA opening and initiation of transcription. SAGA is required for recruitment of the basal transcription machinery. SLIK is proposed to have partly overlapping functions with SAGA.
messages: Nucleus

931890:Ecym 2603
gene id: 931890:Ecym_2603
uniprot id: G8JQI3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 10 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 4387
gene id: 931890:Ecym_4387
uniprot id: G8JTT9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL29 family.

931890:Ecym 1173
gene id: 931890:Ecym_1173
uniprot id: G8JMV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Nucleus

931890:Ecym 5181
gene id: 931890:Ecym_5181
uniprot id: I6ND12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PAM17 family.
messages: Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Component of the PAM complex.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8248
gene id: 931890:Ecym_8248
uniprot id: G8JXF7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

931890:Ecym 1488
gene id: 931890:Ecym_1488
uniprot id: G8JMJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNU66/SART1 family.
messages: Nucleus

931890:Ecym 4043
gene id: 931890:Ecym_4043
uniprot id: G8JSX1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the shugoshin family.
messages: centromere

931890:Ecym 6028
gene id: 931890:Ecym_6028
uniprot id: G8JUV4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS1/PSF1 family.
messages: Component of the GINS complex.
messages: Nucleus
messages: Required for correct functioning of the GINS complex, a complex that plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA.

931890:Ecym 3279
gene id: 931890:Ecym_3279
uniprot id: G8JRK3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP1/IKA1 family.
messages: Component of the elongator complex which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 2554
gene id: 931890:Ecym_2554
uniprot id: G8JQB6
names: Similarity
messages: Belongs to the CWC21 family.

931890:Ecym 2355
gene id: 931890:Ecym_2355
uniprot id: G8JNM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

931890:Ecym 5314
gene id: 931890:Ecym_5314
uniprot id: I6NDD3
names: Similarity
messages: Belongs to the MNN1/MNT family.

931890:Ecym 7060
gene id: 931890:Ecym_7060
uniprot id: G8JVP8
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5058
gene id: 931890:Ecym_5058
uniprot id: I6NCQ6
names: Function
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 2 family.
messages: Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

931890:Ecym 5483
gene id: 931890:Ecym_5483
uniprot id: I6NDT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: cis-Golgi network

931890:Ecym 7149
gene id: 931890:Ecym_7149
uniprot id: G8JVY3
names: Similarity
messages: Belongs to the WD repeat rae1 family.

931890:Ecym 1332
gene id: 931890:Ecym_1332
uniprot id: G8JNA3
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

931890:Ecym 4704
gene id: 931890:Ecym_4704
uniprot id: G8JSK2
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

931890:Ecym 3517
gene id: 931890:Ecym_3517
uniprot id: G8JQL1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the helicase family. RAD3/XPD subfamily.
messages: Nucleus

931890:Ecym 2577
gene id: 931890:Ecym_2577
uniprot id: G8JQG0
names: Similarity
messages: Belongs to the SAPS family.

931890:Ecym 1249
gene id: 931890:Ecym_1249
uniprot id: G8JN28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

931890:Ecym 7131
gene id: 931890:Ecym_7131
uniprot id: G8JVW6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M24 family.
messages: Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
messages: Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.
messages: Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
messages: Cytoplasm

931890:Ecym 1526
gene id: 931890:Ecym_1526
uniprot id: G8JMT2
names: Similarity
messages: Belongs to the multicopper oxidase family.

931890:Ecym 4101
gene id: 931890:Ecym_4101
uniprot id: G8JT27
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

931890:Ecym 6317
gene id: 931890:Ecym_6317
uniprot id: G8JUB5
names: Similarity
messages: Belongs to the peptidase M28 family.

931890:Ecym 7198
gene id: 931890:Ecym_7198
uniprot id: G8JW31
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.
messages: Produces ATP from ADP in the presence of a proton gradient across the membrane.

931890:Ecym 8070
gene id: 931890:Ecym_8070
uniprot id: G8JWZ2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1445
gene id: 931890:Ecym_1445
uniprot id: G8JMF4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL38 family.

931890:Ecym 6147
gene id: 931890:Ecym_6147
uniprot id: G8JV59
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4253
gene id: 931890:Ecym_4253
uniprot id: G8JTG5
names: Function
messages: Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

931890:Ecym 7222
gene id: 931890:Ecym_7222
uniprot id: G8JW53
names: Similarity
messages: Belongs to the SPT2 family.

931890:Ecym 2010
gene id: 931890:Ecym_2010
uniprot id: G8JNG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

931890:Ecym 6398
gene id: 931890:Ecym_6398
uniprot id: G8JUJ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

931890:Ecym 4171
gene id: 931890:Ecym_4171
uniprot id: G8JT95
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

931890:Ecym 5668
gene id: 931890:Ecym_5668
uniprot id: I6NEA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

931890:Ecym 1132
gene id: 931890:Ecym_1132
uniprot id: G8JMM9
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 1126
gene id: 931890:Ecym_1126
uniprot id: G8JMM4
names: Similarity
messages: Belongs to the allantoicase family.

931890:Ecym 6304
gene id: 931890:Ecym_6304
uniprot id: G8JUA4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the proteasome subunit S5B/HSM3 family.
messages: Cytoplasm
messages: Involved in DNA mismatch repair in slow-growing cells. Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC).

931890:Ecym 2556
gene id: 931890:Ecym_2556
uniprot id: G8JQB7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ODC antizyme family.
messages: Interacts with ODC and thereby sterically blocks ODC homodimerization.
messages: Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome.

931890:Ecym 3334
gene id: 931890:Ecym_3334
uniprot id: G8JRQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sphingosine N-acyltransferase family.
messages: Membrane

931890:Ecym 2715
gene id: 931890:Ecym_2715
uniprot id: G8JPF3
names: Similarity
messages: Belongs to the RNR ribonuclease family.

931890:Ecym 7035
gene id: 931890:Ecym_7035
uniprot id: G8JVM6
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

931890:Ecym 3148
gene id: 931890:Ecym_3148
uniprot id: G8JR82
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the exportin family.
messages: Cytoplasm
messages: Nucleus
messages: tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex.

931890:Ecym 4230
gene id: 931890:Ecym_4230
uniprot id: G8JTE4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8365
gene id: 931890:Ecym_8365
uniprot id: G8JXR4
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931890:Ecym 2021
gene id: 931890:Ecym_2021
uniprot id: G8JNY0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

931890:Ecym 3614
gene id: 931890:Ecym_3614
uniprot id: G8JQU1
names: Similarity
messages: Belongs to the MOG1 family.

931890:Ecym 6435
gene id: 931890:Ecym_6435
uniprot id: G8JUM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DTD family.
messages: Cytoplasm

931890:Ecym 4544
gene id: 931890:Ecym_4544
uniprot id: G8JU76
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 7411
gene id: 931890:Ecym_7411
uniprot id: G8JWM1
names: Caution
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPG/RAD2 endonuclease family. FEN1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Interacts with PCNA. Three molecules of FEN1 bind to one PCNA trimer with each molecule binding to one PCNA monomer. PCNA stimulates the nuclease activity without altering cleavage specificity.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion
messages: Phosphorylated. Phosphorylation upon DNA damage induces relocalization to the nuclear plasma.
messages: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structures that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 4569
gene id: 931890:Ecym_4569
uniprot id: G8JS80
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the class II fructose-bisphosphate aldolase family.
messages: Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.
messages: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.

931890:Ecym 1489
gene id: 931890:Ecym_1489
uniprot id: G8JMJ6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP5/NOP56 family.
messages: nucleolus

931890:Ecym 4231
gene id: 931890:Ecym_4231
uniprot id: G8JTE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal Na(+)/H(+) exchanger family.
messages: Membrane

931890:Ecym 2559
gene id: 931890:Ecym_2559
uniprot id: G8JQC0
names: Similarity
messages: Belongs to the TTC4 family.

931890:Ecym 4520
gene id: 931890:Ecym_4520
uniprot id: G8JU54
names: Similarity
messages: Belongs to the CENP-X/MHF2 family.

931890:Ecym 3014
gene id: 931890:Ecym_3014
uniprot id: G8JQW3
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the phosphohexose mutase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, which is a biosynthetic precursor of chitin and also supplies the amino sugars for N-linked oligosaccharides of glycoproteins.

931890:Ecym 4781
gene id: 931890:Ecym_4781
uniprot id: G8JSS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 4653
gene id: 931890:Ecym_4653
uniprot id: G8JSF3
names: Similarity
messages: Belongs to the WD repeat L(2)GL family.

931890:Ecym 7423
gene id: 931890:Ecym_7423
uniprot id: G8JWN1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPS2 family.
messages: Cell membrane
messages: Membrane

931890:Ecym 8267
gene id: 931890:Ecym_8267
uniprot id: G8JXH5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGM family.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN-acyl-PI during GPI precursor assembly. Required for cell wall integrity.
messages: Membrane

931890:Ecym 8190
gene id: 931890:Ecym_8190
uniprot id: G8JXA1
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

931890:Ecym 8340
gene id: 931890:Ecym_8340
uniprot id: G8JXP4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL33 family.

931890:Ecym 4731
gene id: 931890:Ecym_4731
uniprot id: G8JSM7
names: Similarity
messages: Belongs to the epsin family.

931890:Ecym 2602
gene id: 931890:Ecym_2602
uniprot id: G8JQI2
names: Similarity
messages: Belongs to the PAPS reductase family. CysH subfamily.

931890:Ecym 2586
gene id: 931890:Ecym_2586
uniprot id: G8JQG8
names: Function
names: Similarity
messages: Catalyzes the second and fifth step in the 'de novo' purine biosynthesis pathway; contains phosphoribosylamine--glycine ligase (GARS) and phosphoribosylformylglycinamidine cyclo-ligase (AIRS) activities.
messages: In the C-terminal section; belongs to the AIR synthase family.
messages: In the N-terminal section; belongs to the GARS family.

931890:Ecym 4113
gene id: 931890:Ecym_4113
uniprot id: G8JT39
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.

931890:Ecym 6159
gene id: 931890:Ecym_6159
uniprot id: G8JV68
names: Function
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. uL10 forms part of the P stalk that participates in recruiting G proteins to the ribosome.

931890:Ecym 5274
gene id: 931890:Ecym_5274
uniprot id: I6ND95
names: Similarity
messages: Belongs to the PPP phosphatase family.

931890:Ecym 4789
gene id: 931890:Ecym_4789
uniprot id: G8JSS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 3099
gene id: 931890:Ecym_3099
uniprot id: G8JR38
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

931890:Ecym 7474
gene id: 931890:Ecym_7474
uniprot id: G8JWS6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4671
gene id: 931890:Ecym_4671
uniprot id: G8JSH0
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

931890:Ecym 2162
gene id: 931890:Ecym_2162
uniprot id: G8JNJ8
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

931890:Ecym 5144
gene id: 931890:Ecym_5144
uniprot id: I6NCX9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGM101 family.
messages: mitochondrion nucleoid

931890:Ecym 6189
gene id: 931890:Ecym_6189
uniprot id: G8JV93
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX15/CtaA family.
messages: Membrane

931890:Ecym 4522
gene id: 931890:Ecym_4522
uniprot id: G8JU56
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIP1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 1354
gene id: 931890:Ecym_1354
uniprot id: G8JNC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EDC3 family.
messages: P-body

931890:Ecym 1102
gene id: 931890:Ecym_1102
uniprot id: G8JMK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTC4 family.
messages: May be involved in a process influencing telomere capping.
messages: Nucleus

931890:Ecym 5283
gene id: 931890:Ecym_5283
uniprot id: I6NDA3
names: Similarity
messages: Belongs to the SF3A2 family.

931890:Ecym 5071
gene id: 931890:Ecym_5071
uniprot id: I6NCR9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

931890:Ecym 8007
gene id: 931890:Ecym_8007
uniprot id: G8JXX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STE12 transcription factor family.
messages: Nucleus

931890:Ecym 2236
gene id: 931890:Ecym_2236
uniprot id: G8JPM8
names: Subcellular Location Annotation
messages: nuclear pore complex

931890:Ecym 3158
gene id: 931890:Ecym_3158
uniprot id: G8JR92
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6229
gene id: 931890:Ecym_6229
uniprot id: G8JVD2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4669
gene id: 931890:Ecym_4669
uniprot id: G8JSG8
names: Similarity
messages: Belongs to the TIP41 family.

931890:Ecym 6188
gene id: 931890:Ecym_6188
uniprot id: G8JV92
names: Similarity
messages: Belongs to the alkylbase DNA glycosidase AlkA family.

931890:Ecym 1311
gene id: 931890:Ecym_1311
uniprot id: G8JN85
names: Similarity
messages: Belongs to the lysophospholipase family.

931890:Ecym 8178
gene id: 931890:Ecym_8178
uniprot id: G8JX90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD4 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 2502
gene id: 931890:Ecym_2502
uniprot id: G8JPW6
names: Similarity
messages: In the C-terminal section; belongs to the anthranilate synthase component I family.

931890:Ecym 6466
gene id: 931890:Ecym_6466
uniprot id: G8JUQ7
names: Similarity
messages: Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.

931890:Ecym 2814
gene id: 931890:Ecym_2814
uniprot id: G8JQE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the glycosyltransferase 2 family.
messages: Component of the dolichol-phosphate mannose (DPM) synthase complex.
messages: Endoplasmic reticulum
messages: Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.

931890:Ecym 7093
gene id: 931890:Ecym_7093
uniprot id: G8JVT0
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

931890:Ecym 8376
gene id: 931890:Ecym_8376
uniprot id: G8JXS2
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.

931890:Ecym 3369
gene id: 931890:Ecym_3369
uniprot id: G8JRT7
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

931890:Ecym 8418
gene id: 931890:Ecym_8418
uniprot id: G8JXW3
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5575
gene id: 931890:Ecym_5575
uniprot id: I6NE21
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Chromosome
messages: Key enzyme involved in DNA replication and DNA repair. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA.
messages: Nucleus

931890:Ecym 6484
gene id: 931890:Ecym_6484
uniprot id: G8JUS3
names: Caution
names: Similarity
messages: Belongs to the globin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931890:Ecym 6380
gene id: 931890:Ecym_6380
uniprot id: G8JUH5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic RPC7 RNA polymerase subunit family.
messages: Component of the RNA polymerase III (Pol III) complex.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

931890:Ecym 7068
gene id: 931890:Ecym_7068
uniprot id: G8JVQ6
names: Similarity
messages: Belongs to the transglutaminase-like superfamily. PNGase family.

931890:Ecym 7185
gene id: 931890:Ecym_7185
uniprot id: G8JW18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oligopeptide OPT transporter family.
messages: Membrane

931890:Ecym 4179
gene id: 931890:Ecym_4179
uniprot id: G8JTA2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

931890:Ecym 5429
gene id: 931890:Ecym_5429
uniprot id: I6NDP1
names: Similarity
messages: Belongs to the malate synthase family.

931890:Ecym 6279
gene id: 931890:Ecym_6279
uniprot id: G8JVI0
names: Similarity
messages: Belongs to the PAF1 family.

931890:Ecym 4685
gene id: 931890:Ecym_4685
uniprot id: G8JSI4
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 6343
gene id: 931890:Ecym_6343
uniprot id: G8JUD9
names: Similarity
messages: Belongs to the helicase family. UvrD subfamily.

931890:Ecym 5654
gene id: 931890:Ecym_5654
uniprot id: I6NE96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF4 family.
messages: Membrane

931890:Ecym 5514
gene id: 931890:Ecym_5514
uniprot id: I6NDW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC110 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Potential role in cross-linking filaments or anchoring other molecules. It is essential for growth.
messages: Nucleus
messages: spindle pole body

931890:Ecym 7086
gene id: 931890:Ecym_7086
uniprot id: G8JVS3
names: Subcellular Location Annotation
messages: Peroxisome membrane

931890:Ecym 8077
gene id: 931890:Ecym_8077
uniprot id: G8JWZ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP14 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm.
messages: nucleolus

931890:Ecym 7295
gene id: 931890:Ecym_7295
uniprot id: G8JWB8
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

931890:Ecym 4566
gene id: 931890:Ecym_4566
uniprot id: G8JS77
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 2 family.
messages: Nucleus
messages: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity.

931890:Ecym 4561
gene id: 931890:Ecym_4561
uniprot id: G8JU91
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 3261
gene id: 931890:Ecym_3261
uniprot id: G8JRI5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fungal cytochrome c oxidase subunit 7a family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8385
gene id: 931890:Ecym_8385
uniprot id: G8JXT1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4614
gene id: 931890:Ecym_4614
uniprot id: G8JSC1
names: Similarity
messages: Belongs to the peptidase A1 family.

931890:Ecym 5671
gene id: 931890:Ecym_5671
uniprot id: I6NEB1
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 8362
gene id: 931890:Ecym_8362
uniprot id: G8JXR1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7391
gene id: 931890:Ecym_7391
uniprot id: G8JWK2
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931890:Ecym 4427
gene id: 931890:Ecym_4427
uniprot id: G8JTX2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
messages: Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
messages: Cytoplasm
messages: Nucleus

931890:Ecym 5232
gene id: 931890:Ecym_5232
uniprot id: I6ND58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ASF1 family.
messages: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly.
messages: Interacts with histone H3.
messages: Nucleus

931890:Ecym 6227
gene id: 931890:Ecym_6227
uniprot id: G8JVD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sideroflexin family.
messages: Membrane
messages: Mitochondrion membrane

931890:Ecym 8135
gene id: 931890:Ecym_8135
uniprot id: G8JX52
names: Similarity
messages: Belongs to the CDC6/cdc18 family.

931890:Ecym 1505
gene id: 931890:Ecym_1505
uniprot id: G8JMR4
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

931890:Ecym 7383
gene id: 931890:Ecym_7383
uniprot id: G8JWJ4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aldolase class II family. MtnB subfamily.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P).
messages: Cytoplasm

931890:Ecym 4337
gene id: 931890:Ecym_4337
uniprot id: G8JTP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PET117 family.
messages: Mitochondrion

931890:Ecym 7263
gene id: 931890:Ecym_7263
uniprot id: G8JW92
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 4184
gene id: 931890:Ecym_4184
uniprot id: G8JTA7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4251
gene id: 931890:Ecym_4251
uniprot id: G8JTG3
names: Similarity
messages: Belongs to the peptidase A1 family.

931890:Ecym 4646
gene id: 931890:Ecym_4646
uniprot id: G8JSE7
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 8245
gene id: 931890:Ecym_8245
uniprot id: G8JXF5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrD/CARKD family.
messages: Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.
messages: Cytoplasm

931890:Ecym 6409
gene id: 931890:Ecym_6409
uniprot id: G8JUK2
names: Similarity
messages: Belongs to the archaeal Rpo12/eukaryotic RPC10 RNA polymerase subunit family.

931890:Ecym 4121
gene id: 931890:Ecym_4121
uniprot id: G8JT47
names: Similarity
messages: Belongs to the universal ribosomal protein uL10 family.

931890:Ecym 5615
gene id: 931890:Ecym_5615
uniprot id: I6NE59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

931890:Ecym 8396
gene id: 931890:Ecym_8396
uniprot id: G8JXU2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS8 family. Ribosome biogenesis protein NSA2 subfamily.
messages: Component of the pre-66S ribosomal particle.
messages: Involved in the biogenesis of the 60S ribosomal subunit. May play a part in the quality control of pre-60S particles.
messages: nucleolus

931890:Ecym 1418
gene id: 931890:Ecym_1418
uniprot id: G8JM75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HOP2 family.
messages: Nucleus

931890:Ecym 1177
gene id: 931890:Ecym_1177
uniprot id: G8JMW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM50 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 7373
gene id: 931890:Ecym_7373
uniprot id: G8JWI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ELP2 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 4080
gene id: 931890:Ecym_4080
uniprot id: G8JT06
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGS family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2447
gene id: 931890:Ecym_2447
uniprot id: G8JPB8
names: Function
names: Similarity
messages: Belongs to the APS kinase family.
messages: Catalyzes the synthesis of activated sulfate.

931890:Ecym 4675
gene id: 931890:Ecym_4675
uniprot id: G8JSH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG8 family.
messages: Membrane
messages: Vacuole membrane
messages: autophagosome membrane

931890:Ecym 1084
gene id: 931890:Ecym_1084
uniprot id: G8JMD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 5025
gene id: 931890:Ecym_5025
uniprot id: I6NCN3
names: Cofactor
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase family.
messages: Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.

931890:Ecym 2219
gene id: 931890:Ecym_2219
uniprot id: G8JP63
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 1170
gene id: 931890:Ecym_1170
uniprot id: G8JMV6
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

931890:Ecym 8082
gene id: 931890:Ecym_8082
uniprot id: G8JX03
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 5150
gene id: 931890:Ecym_5150
uniprot id: I6NCY5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IML1 family.
messages: Vacuole membrane

931890:Ecym 1471
gene id: 931890:Ecym_1471
uniprot id: G8JMI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF9 family.
messages: Nucleus

931890:Ecym 5570
gene id: 931890:Ecym_5570
uniprot id: I6NE16
names: Similarity
messages: Belongs to the TFIIB family.

931890:Ecym 6255
gene id: 931890:Ecym_6255
uniprot id: G8JVF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL53 family.
messages: Mitochondrion

931890:Ecym 8228
gene id: 931890:Ecym_8228
uniprot id: G8JXD9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.

931890:Ecym 8244
gene id: 931890:Ecym_8244
uniprot id: G8JXF4
names: Similarity
messages: Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

931890:Ecym 1334
gene id: 931890:Ecym_1334
uniprot id: G8JNA5
names: Subcellular Location Annotation
messages: Vacuole

931890:Ecym 8072
gene id: 931890:Ecym_8072
uniprot id: G8JWZ4
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network.

931890:Ecym 5076
gene id: 931890:Ecym_5076
uniprot id: I6NCS4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
messages: Belongs to the NSE1 family.
messages: Component of the Smc5-Smc6 complex.
messages: Nucleus

931890:Ecym 5409
gene id: 931890:Ecym_5409
uniprot id: I6NDM1
names: Similarity
messages: Belongs to the DNA polymerase type-B family.

931890:Ecym 1368
gene id: 931890:Ecym_1368
uniprot id: G8JND7
names: Similarity
messages: Belongs to the PET191 family.

931890:Ecym 5621
gene id: 931890:Ecym_5621
uniprot id: I6NE65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors GET1 and GET2, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. Subsequently, the homodimer reverts towards the open dimer state, lowering its affinity for the GET1-GET2 receptor, and returning it to the cytosol to initiate a new round of targeting. Cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. Involved in low-level resistance to the oxyanions arsenite and arsenate, and in heat tolerance.
messages: Belongs to the arsA ATPase family.
messages: Cytoplasm
messages: Endoplasmic reticulum
messages: Golgi apparatus
messages: Homodimer. Component of the Golgi to ER traffic (GET) complex, which is composed of GET1, GET2 and GET3. Within the complex, GET1 and GET2 form a heterotetramer which is stabilized by phosphatidylinositol binding and which binds to the GET3 homodimer. Interacts with the chloride channel protein GEF1.

931890:Ecym 5638
gene id: 931890:Ecym_5638
uniprot id: I6NE82
names: Cofactor
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.
messages: Binds 1 Mg(2+) ion per monomer.
messages: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis.
messages: Cytoplasm
messages: Monomer.
messages: Nucleus

931890:Ecym 5104
gene id: 931890:Ecym_5104
uniprot id: I6NCU5
names: Similarity
messages: Belongs to the FMO family.

931890:Ecym 1113
gene id: 931890:Ecym_1113
uniprot id: G8JML2
names: Similarity
messages: Belongs to the SUI1 family.

931890:Ecym 3047
gene id: 931890:Ecym_3047
uniprot id: G8JQZ1
names: Similarity
messages: Belongs to the OPA3 family.

931890:Ecym 3122
gene id: 931890:Ecym_3122
uniprot id: G8JR57
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferrochelatase family.
messages: Catalyzes the ferrous insertion into protoporphyrin IX.
messages: Mitochondrion inner membrane

931890:Ecym 1378
gene id: 931890:Ecym_1378
uniprot id: G8JNE7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup85 family.
messages: Component of the nuclear pore complex (NPC).
messages: Functions as a component of the nuclear pore complex (NPC).
messages: nuclear pore complex

931890:Ecym 3016
gene id: 931890:Ecym_3016
uniprot id: G8JQW5
names: Similarity
messages: Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.

931890:Ecym 2741
gene id: 931890:Ecym_2741
uniprot id: G8JPH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

931890:Ecym 4132
gene id: 931890:Ecym_4132
uniprot id: G8JT58
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CCC1 family.
messages: Membrane

931890:Ecym 4108
gene id: 931890:Ecym_4108
uniprot id: G8JT34
names: Similarity
messages: Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.

931890:Ecym 4354
gene id: 931890:Ecym_4354
uniprot id: G8JTR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane magnesium transporter (TC 1.A.67) family.
messages: Membrane

931890:Ecym 1004
gene id: 931890:Ecym_1004
uniprot id: G8JML2
names: Similarity
messages: Belongs to the SUI1 family.

931890:Ecym 3221
gene id: 931890:Ecym_3221
uniprot id: G8JRE9
names: Domain
names: Function
names: Similarity
messages: Belongs to the IPK1 type 1 family.
messages: Has kinase activity and phosphorylates inositol-1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5) to produce 1,2,3,4,5,6-hexakisphosphate (InsP6), also known as phytate.
messages: Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate).
messages: The EXKPK motif is conserved in inositol-pentakisphosphate 2-kinases of both family 1 and 2.

931890:Ecym 7375
gene id: 931890:Ecym_7375
uniprot id: G8JWI6
names: Similarity
messages: Belongs to the cytidylyltransferase family.

931890:Ecym 8301
gene id: 931890:Ecym_8301
uniprot id: G8JXK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFR1/MEI5 family.
messages: Nucleus

931890:Ecym 5642
gene id: 931890:Ecym_5642
uniprot id: I6NE85
names: Similarity
messages: Belongs to the peptidase S10 family.

931890:Ecym 3486
gene id: 931890:Ecym_3486
uniprot id: G8JS50
names: Function
names: Similarity
messages: Belongs to the SEC8 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

931890:Ecym 4202
gene id: 931890:Ecym_4202
uniprot id: G8JTB7
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ZIP transporter (TC 2.A.5) family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 2615
gene id: 931890:Ecym_2615
uniprot id: G8JQJ5
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7264
gene id: 931890:Ecym_7264
uniprot id: G8JW93
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1390
gene id: 931890:Ecym_1390
uniprot id: G8JM49
names: Function
names: Similarity
messages: Belongs to the phytoene/squalene synthase family.
messages: Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene.

931890:Ecym 6478
gene id: 931890:Ecym_6478
uniprot id: G8JUR8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GST superfamily.
messages: Homodimer.
messages: Plays an important role in the cellular response to the nitrogen source.

931890:Ecym 5631
gene id: 931890:Ecym_5631
uniprot id: I6NE75
names: Similarity
messages: Belongs to the lipin family.

931890:Ecym 8240
gene id: 931890:Ecym_8240
uniprot id: G8JXF0
names: Similarity
messages: Belongs to the nucleoporin NSP1/NUP62 family.

931890:Ecym 4445
gene id: 931890:Ecym_4445
uniprot id: G8JTY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 5408
gene id: 931890:Ecym_5408
uniprot id: I6NDM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 6212
gene id: 931890:Ecym_6212
uniprot id: G8JVB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS26 family.

931890:Ecym 5136
gene id: 931890:Ecym_5136
uniprot id: I6NCX1
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

931890:Ecym 3060
gene id: 931890:Ecym_3060
uniprot id: G8JR03
names: Similarity
messages: Belongs to the glycosyl hydrolase 31 family.

931890:Ecym 7240
gene id: 931890:Ecym_7240
uniprot id: G8JW70
names: Function
names: Similarity
messages: Belongs to the UDPGP type 1 family.
messages: Plays a central role as a glucosyl donor in cellular metabolic pathways.

931890:Ecym 2164
gene id: 931890:Ecym_2164
uniprot id: G8JNK0
names: Similarity
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.

931890:Ecym 2359
gene id: 931890:Ecym_2359
uniprot id: G8JNM5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TBCA family.
messages: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
messages: cytoskeleton

931890:Ecym 4713
gene id: 931890:Ecym_4713
uniprot id: G8JSL1
names: Cofactor
names: Similarity
messages: Belongs to the glutamate synthase family.
messages: Binds 1 [3Fe-4S] cluster.

931890:Ecym 6149
gene id: 931890:Ecym_6149
uniprot id: G8JV61
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 3198
gene id: 931890:Ecym_3198
uniprot id: G8JRC8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGF family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 3495
gene id: 931890:Ecym_3495
uniprot id: G8JS57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TDA2 family.
messages: Cell projection
messages: Cytoplasm

931890:Ecym 1051
gene id: 931890:Ecym_1051
uniprot id: G8JMA0
names: Similarity
messages: In the C-terminal section; belongs to the histidinol dehydrogenase family.

931890:Ecym 5255
gene id: 931890:Ecym_5255
uniprot id: I6ND79
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 5119
gene id: 931890:Ecym_5119
uniprot id: I6NCV7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GLE1 family.
messages: nuclear pore complex

931890:Ecym 4723
gene id: 931890:Ecym_4723
uniprot id: G8JSM1
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.

931890:Ecym 6087
gene id: 931890:Ecym_6087
uniprot id: G8JV04
names: Miscellaneous
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.
messages: Homodimer.
messages: In eukaryotes there are cytoplasmic, mitochondrial and chloroplastic isozymes.

931890:Ecym 4438
gene id: 931890:Ecym_4438
uniprot id: G8JTY1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom5 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 3331
gene id: 931890:Ecym_3331
uniprot id: G8JRQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP25 family.
messages: Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.
messages: DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2.
messages: nucleolus

931890:Ecym 5063
gene id: 931890:Ecym_5063
uniprot id: I6NCR1
names: Subcellular Location Annotation
messages: Mitochondrion

931890:Ecym 6453
gene id: 931890:Ecym_6453
uniprot id: G8JUP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7243
gene id: 931890:Ecym_7243
uniprot id: G8JW73
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

931890:Ecym 4488
gene id: 931890:Ecym_4488
uniprot id: G8JU24
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DDOST 48 kDa subunit family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER).

931890:Ecym 5072
gene id: 931890:Ecym_5072
uniprot id: I6NCS0
names: Similarity
messages: Belongs to the MAK16 family.

931890:Ecym 2379
gene id: 931890:Ecym_2379
uniprot id: G8JNP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG29 family.
messages: Preautophagosomal structure

931890:Ecym 6007
gene id: 931890:Ecym_6007
uniprot id: G8JUT6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes medium subunit family. Delta-COP subfamily.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

931890:Ecym 5253
gene id: 931890:Ecym_5253
uniprot id: I6ND77
names: Similarity
messages: Belongs to the SAICAR synthetase family.

931890:Ecym 1151
gene id: 931890:Ecym_1151
uniprot id: G8JMP7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

931890:Ecym 4305
gene id: 931890:Ecym_4305
uniprot id: G8JTL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the securin family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 1253
gene id: 931890:Ecym_1253
uniprot id: G8JN31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

931890:Ecym 1495
gene id: 931890:Ecym_1495
uniprot id: G8JMK2
names: Similarity
messages: Belongs to the SUN family.

931890:Ecym 5336
gene id: 931890:Ecym_5336
uniprot id: I6NDF3
names: Function
names: Similarity
messages: Belongs to the HTP reductase family.
messages: Catalyzes an early step in riboflavin biosynthesis, the NADPH-dependent reduction of the ribose side chain of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, yielding 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate.

931890:Ecym 2314
gene id: 931890:Ecym_2314
uniprot id: G8JQ54
names: Similarity
names: Subunit
messages: Belongs to the ubiquitin-activating E1 family.
messages: Heterodimer.

931890:Ecym 6106
gene id: 931890:Ecym_6106
uniprot id: G8JV21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
messages: actin patch

931890:Ecym 7418
gene id: 931890:Ecym_7418
uniprot id: G8JWM7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the LTN1 family.
messages: Component of the ribosome quality control complex (RQC).
messages: E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation.
messages: cytosol

931890:Ecym 4592
gene id: 931890:Ecym_4592
uniprot id: G8JSA2
names: Similarity
messages: Belongs to the pterin-4-alpha-carbinolamine dehydratase family.

931890:Ecym 1530
gene id: 931890:Ecym_1530
uniprot id: G8JMT5
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Hydrolase that can remove conjugated ubiquitin from proteins and may therefore play an important regulatory role at the level of protein turnover by preventing degradation.

931890:Ecym 8087
gene id: 931890:Ecym_8087
uniprot id: G8JX08
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DP1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 4245
gene id: 931890:Ecym_4245
uniprot id: G8JTF7
names: Similarity
messages: Belongs to the eukaryotic/archaeal PrmC-related family.

931890:Ecym 4547
gene id: 931890:Ecym_4547
uniprot id: G8JU79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 4049
gene id: 931890:Ecym_4049
uniprot id: G8JSX7
names: Similarity
messages: Belongs to the RNase Z family.

931890:Ecym 5124
gene id: 931890:Ecym_5124
uniprot id: I6NCW1
names: Caution
names: Subcellular Location Annotation
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 4534
gene id: 931890:Ecym_4534
uniprot id: G8JU67
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.
messages: Endoplasmic reticulum
messages: Part of the multisubunit TRAPP (transport protein particle) complex.
messages: Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic.
messages: cis-Golgi network

931890:Ecym 7333
gene id: 931890:Ecym_7333
uniprot id: G8JWF0
names: Similarity
messages: Belongs to the peptidase M67A family.

931890:Ecym 6155
gene id: 931890:Ecym_6155
uniprot id: G8JV66
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 4422
gene id: 931890:Ecym_4422
uniprot id: G8JTW8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the pescadillo family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 6230
gene id: 931890:Ecym_6230
uniprot id: G8JVD3
names: Function
names: Similarity
messages: Belongs to the misato family.
messages: Involved in the partitioning of the mitochondrial organelle and mitochondrial DNA (mtDNA) inheritance.

931890:Ecym 7421
gene id: 931890:Ecym_7421
uniprot id: G8JWM9
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic AdoMetDC family.
messages: Binds 1 pyruvoyl group covalently per subunit.

931890:Ecym 5494
gene id: 931890:Ecym_5494
uniprot id: I6NDU6
names: Function
names: Similarity
messages: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
messages: Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid.

931890:Ecym 2476
gene id: 931890:Ecym_2476
uniprot id: G8JPU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku80 family.
messages: Nucleus
messages: telomere

931890:Ecym 7457
gene id: 931890:Ecym_7457
uniprot id: G8JWR1
names: Similarity
messages: Belongs to the acetyltransferase family. MAK3 subfamily.

931890:Ecym 3574
gene id: 931890:Ecym_3574
uniprot id: G8JQR0
names: PTM
names: Similarity
messages: Belongs to the eIF-5A family.
messages: eIF-5A seems to be the only eukaryotic protein to have a hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group.

931890:Ecym 3257
gene id: 931890:Ecym_3257
uniprot id: G8JRI1
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

931890:Ecym 8099
gene id: 931890:Ecym_8099
uniprot id: G8JX19
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

931890:Ecym 5520
gene id: 931890:Ecym_5520
uniprot id: I6NDW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 6080
gene id: 931890:Ecym_6080
uniprot id: G8JUZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NCBP1 family.
messages: Nucleus

931890:Ecym 3056
gene id: 931890:Ecym_3056
uniprot id: G8JQZ9
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

931890:Ecym 8050
gene id: 931890:Ecym_8050
uniprot id: G8JWX2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase alpha/beta chains family.
messages: Endomembrane system
messages: Vacuole membrane

931890:Ecym 6205
gene id: 931890:Ecym_6205
uniprot id: G8JVA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 4693
gene id: 931890:Ecym_4693
uniprot id: G8JSJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CMC family.
messages: Mitochondrion inner membrane
messages: Required for mitochondrial cytochrome c oxidase (COX) assembly and respiration.

931890:Ecym 4577
gene id: 931890:Ecym_4577
uniprot id: G8JS88
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

931890:Ecym 2079
gene id: 931890:Ecym_2079
uniprot id: G8JPI6
names: Similarity
messages: Belongs to the KNR4/SMI1 family.

931890:Ecym 4016
gene id: 931890:Ecym_4016
uniprot id: G8JSU7
names: Similarity
messages: Belongs to the CTAG/PCC1 family.

931890:Ecym 2548
gene id: 931890:Ecym_2548
uniprot id: G8JQB0
names: Similarity
messages: Belongs to the GST superfamily.

931890:Ecym 7115
gene id: 931890:Ecym_7115
uniprot id: G8JVV2
names: Function
names: Similarity
messages: Belongs to the UBR1 family.
messages: Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

931890:Ecym 3615
gene id: 931890:Ecym_3615
uniprot id: G8JQU2
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.

931890:Ecym 7458
gene id: 931890:Ecym_7458
uniprot id: G8JWR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PCNA family.
messages: Nucleus
messages: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand.

931890:Ecym 7176
gene id: 931890:Ecym_7176
uniprot id: G8JW09
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

931890:Ecym 6017
gene id: 931890:Ecym_6017
uniprot id: G8JUU6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBP4 family.
messages: Essential for the assembly of ubiquinol-cytochrome c reductase. It has a direct effect on the correct occurrence of the Rieske protein, core 4, core 5 and apocytochrome b.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 1188
gene id: 931890:Ecym_1188
uniprot id: G8JMX3
names: Similarity
names: Subunit
messages: Belongs to the EXO5 family.
messages: Monomer.

931890:Ecym 4012
gene id: 931890:Ecym_4012
uniprot id: G8JSU3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PTPA-type PPIase family.
messages: Cytoplasm
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 6186
gene id: 931890:Ecym_6186
uniprot id: G8JV90
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

931890:Ecym 2716
gene id: 931890:Ecym_2716
uniprot id: G8JPF4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 8115
gene id: 931890:Ecym_8115
uniprot id: G8JX35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

931890:Ecym 3012
gene id: 931890:Ecym_3012
uniprot id: G8JQW2
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1137
gene id: 931890:Ecym_1137
uniprot id: G8JMN4
names: Similarity
messages: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.

931890:Ecym 3127
gene id: 931890:Ecym_3127
uniprot id: G8JR62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5009
gene id: 931890:Ecym_5009
uniprot id: I6NCM0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS12 family.

931890:Ecym 3518
gene id: 931890:Ecym_3518
uniprot id: G8JQL2
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylate kinase family. AK3 subfamily.
messages: Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon GTP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent GTP hydrolysis.
messages: Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities.
messages: Mitochondrion matrix
messages: Monomer.

931890:Ecym 5032
gene id: 931890:Ecym_5032
uniprot id: I6NCP0
names: Cofactor
names: Function
messages: Accepts electrons from ETF and reduces ubiquinone.
messages: Binds 1 [4Fe-4S] cluster.

931890:Ecym 5243
gene id: 931890:Ecym_5243
uniprot id: I6ND68
names: Similarity
messages: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.

931890:Ecym 4193
gene id: 931890:Ecym_4193
uniprot id: G8JTB5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS35 family.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

931890:Ecym 5100
gene id: 931890:Ecym_5100
uniprot id: I6NCU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 8191
gene id: 931890:Ecym_8191
uniprot id: G8JXA2
names: Similarity
messages: Belongs to the MIP18 family.

931890:Ecym 1358
gene id: 931890:Ecym_1358
uniprot id: G8JNC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NSE2 family.
messages: Nucleus

931890:Ecym 6150
gene id: 931890:Ecym_6150
uniprot id: G8JV62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the dolichyldiphosphatase family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate.

931890:Ecym 2626
gene id: 931890:Ecym_2626
uniprot id: G8JQK6
names: Function
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
messages: Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).

931890:Ecym 5358
gene id: 931890:Ecym_5358
uniprot id: I6NDH4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2319
gene id: 931890:Ecym_2319
uniprot id: G8JQ59
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.

931890:Ecym 7128
gene id: 931890:Ecym_7128
uniprot id: G8JVW3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 19 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 4692
gene id: 931890:Ecym_4692
uniprot id: G8JSJ1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2443
gene id: 931890:Ecym_2443
uniprot id: G8JPB5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL14 family.

931890:Ecym 1068
gene id: 931890:Ecym_1068
uniprot id: G8JMB7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2569
gene id: 931890:Ecym_2569
uniprot id: G8JQC8
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2106
gene id: 931890:Ecym_2106
uniprot id: G8JPL0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 1312
gene id: 931890:Ecym_1312
uniprot id: G8JN86
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.
messages: Cytoplasm

931890:Ecym 2676
gene id: 931890:Ecym_2676
uniprot id: G8JNW1
names: Similarity
names: Subunit
messages: Belongs to the uroporphyrinogen decarboxylase family.
messages: Homodimer.

931890:Ecym 6351
gene id: 931890:Ecym_6351
uniprot id: G8JUE7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Not involved in the GTP-dependent ribosomal translocation step during translation elongation.
messages: Mitochondrion

931890:Ecym 4218
gene id: 931890:Ecym_4218
uniprot id: G8JTD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat TRM82 family.
messages: Forms a heterodimer with the catalytic subunit TRM8.
messages: Nucleus
messages: Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

931890:Ecym 2065
gene id: 931890:Ecym_2065
uniprot id: G8JP22
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

931890:Ecym 4458
gene id: 931890:Ecym_4458
uniprot id: G8JTZ7
names: Similarity
messages: Belongs to the TOP6A family.

931890:Ecym 8197
gene id: 931890:Ecym_8197
uniprot id: G8JXA8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAF1 family.
messages: Nucleus

931890:Ecym 3471
gene id: 931890:Ecym_3471
uniprot id: G8JS35
names: Function
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family. UBA3 subfamily.
messages: Catalytic subunit of the dimeric E1 enzyme, which activates NEDD8.

931890:Ecym 1144
gene id: 931890:Ecym_1144
uniprot id: G8JMP1
names: Similarity
messages: Belongs to the hexokinase family.

931890:Ecym 6245
gene id: 931890:Ecym_6245
uniprot id: G8JVE8
names: Similarity
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.

931890:Ecym 2607
gene id: 931890:Ecym_2607
uniprot id: G8JQI7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX9 family.
messages: Interacts with the 35S, 23S and 20S pre-rRNAs and with the U3 snoRNA.
messages: Involved in ribosome biogenesis. Required for normal pre-rRNA processing in internal transcribed spacer 1 (ITS1). May be involved in the movements of the replication forks.
messages: nucleolus

931890:Ecym 4397
gene id: 931890:Ecym_4397
uniprot id: G8JTU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cut8/STS1 family.
messages: Binds the proteasome.
messages: Cytoplasm
messages: Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins.
messages: Nucleus

931890:Ecym 7307
gene id: 931890:Ecym_7307
uniprot id: G8JWC9
names: Similarity
messages: Belongs to the peptidase C48 family.

931890:Ecym 8086
gene id: 931890:Ecym_8086
uniprot id: G8JX07
names: Similarity
messages: Belongs to the adaptor complexes large subunit family.

931890:Ecym 5319
gene id: 931890:Ecym_5319
uniprot id: I6NDD7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 2436
gene id: 931890:Ecym_2436
uniprot id: G8JPA8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with the pre-60S ribosomal particle.
messages: Belongs to the universal ribosomal protein uL10 family.
messages: Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.
messages: Cytoplasm
messages: nucleolus

931890:Ecym 2587
gene id: 931890:Ecym_2587
uniprot id: G8JQG9
names: Function
names: Similarity
messages: Belongs to the MnmG family.
messages: Involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U34) of the wobble uridine base in mitochondrial tRNAs.

931890:Ecym 2499
gene id: 931890:Ecym_2499
uniprot id: G8JPW3
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

931890:Ecym 2119
gene id: 931890:Ecym_2119
uniprot id: G8JPM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WHI5/NRM1 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 1386
gene id: 931890:Ecym_1386
uniprot id: G8JM46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxygen-dependent FAD-linked oxidoreductase family.
messages: Mitochondrion membrane

931890:Ecym 7043
gene id: 931890:Ecym_7043
uniprot id: G8JVN4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ATPase B chain family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. In yeast, the dimeric form of ATP synthase consists of 17 polypeptides: alpha, beta, gamma, delta, epsilon, 4 (B), 5 (OSCP), 6 (A), 8, 9 (C), d, E (Tim11), f, g, h, i/j and k.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
messages: Mitochondrion
messages: Mitochondrion inner membrane

931890:Ecym 4001
gene id: 931890:Ecym_4001
uniprot id: G8JST2
names: Similarity
messages: Belongs to the lipid-translocating exporter (LTE) (TC 9.A.26.1) family.

931890:Ecym 2812
gene id: 931890:Ecym_2812
uniprot id: G8JQE5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGU family.
messages: Component of the GPI transamidase complex. May be involved in the recognition of either the GPI attachment signal or the lipid portion of GPI.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2631
gene id: 931890:Ecym_2631
uniprot id: G8JNR8
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

931890:Ecym 6401
gene id: 931890:Ecym_6401
uniprot id: G8JUJ5
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL42 family.

931890:Ecym 2472
gene id: 931890:Ecym_2472
uniprot id: G8JPT9
names: Similarity
messages: Belongs to the SSH4 family.

931890:Ecym 6449
gene id: 931890:Ecym_6449
uniprot id: G8JUP0
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

931890:Ecym 8275
gene id: 931890:Ecym_8275
uniprot id: G8JXI3
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7190
gene id: 931890:Ecym_7190
uniprot id: G8JW23
names: Function
names: Similarity
messages: ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives.
messages: Belongs to the carbohydrate kinase PfkB family.

931890:Ecym 3564
gene id: 931890:Ecym_3564
uniprot id: G8JQQ1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4570
gene id: 931890:Ecym_4570
uniprot id: G8JS81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the pex2/pex10/pex12 family.
messages: Peroxisome membrane
messages: Required for protein import into peroxisomes.

931890:Ecym 3309
gene id: 931890:Ecym_3309
uniprot id: G8JRN1
names: Similarity
messages: Belongs to the SHQ1 family.

931890:Ecym 4299
gene id: 931890:Ecym_4299
uniprot id: G8JTK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

931890:Ecym 8165
gene id: 931890:Ecym_8165
uniprot id: G8JX78
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND3 (condensin subunit 3) family.
messages: Chromosome

931890:Ecym 5175
gene id: 931890:Ecym_5175
uniprot id: I6ND06
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Integrase (IN) targets the VLP to the nucleus, where a subparticle preintegration complex (PIC) containing at least integrase and the newly synthesized dsDNA copy of the retrotransposon must transit the nuclear membrane. Once in the nucleus, integrase performs the integration of the dsDNA into the host genome.
messages: Nucleus
messages: Reverse transcriptase/ribonuclease H (RT) is a multifunctional enzyme that catalyzes the conversion of the retro-elements RNA genome into dsDNA within the VLP. The enzyme displays a DNA polymerase activity that can copy either DNA or RNA templates, and a ribonuclease H (RNase H) activity that cleaves the RNA strand of RNA-DNA heteroduplexes during plus-strand synthesis and hydrolyzes RNA primers. The conversion leads to a linear dsDNA copy of the retrotransposon that includes long terminal repeats (LTRs) at both ends.

931890:Ecym 7213
gene id: 931890:Ecym_7213
uniprot id: G8JW45
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

931890:Ecym 8236
gene id: 931890:Ecym_8236
uniprot id: G8JXE7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP receptor beta subunit family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 1393
gene id: 931890:Ecym_1393
uniprot id: G8JM52
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

931890:Ecym 4594
gene id: 931890:Ecym_4594
uniprot id: G8JSA4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LU7TM family.
messages: Membrane

931890:Ecym 2287
gene id: 931890:Ecym_2287
uniprot id: G8JPS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat BOP1/ERB1 family.
messages: Component of the NOP7 complex, composed of ERB1, NOP7 and YTM1. Within the NOP7 complex ERB1 appears to interact directly with NOP7 and YTM1. The NOP7 complex also associates with the 66S pre-ribosome.
messages: Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 4688
gene id: 931890:Ecym_4688
uniprot id: G8JSI7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

931890:Ecym 7290
gene id: 931890:Ecym_7290
uniprot id: G8JWB3
names: Similarity
messages: Belongs to the ClpA/ClpB family.

931890:Ecym 8315
gene id: 931890:Ecym_8315
uniprot id: G8JXL9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H1/H5 family.
messages: Nucleus

931890:Ecym 7064
gene id: 931890:Ecym_7064
uniprot id: G8JVQ2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

931890:Ecym 7303
gene id: 931890:Ecym_7303
uniprot id: G8JWC6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC1 subfamily.
messages: Nucleus

931890:Ecym 1217
gene id: 931890:Ecym_1217
uniprot id: G8JN00
names: Similarity
messages: Belongs to the peptidase S10 family.

931890:Ecym 3063
gene id: 931890:Ecym_3063
uniprot id: G8JR06
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

931890:Ecym 6469
gene id: 931890:Ecym_6469
uniprot id: G8JUR0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adenylosuccinate synthetase family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Cytoplasm
messages: Homodimer.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.
messages: Plays an important role in the de novo pathway of purine nucleotide biosynthesis.

931890:Ecym 1099
gene id: 931890:Ecym_1099
uniprot id: G8JME6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: DNA polymerase II participates in chromosomal DNA replication.
messages: Nucleus

931890:Ecym 1015
gene id: 931890:Ecym_1015
uniprot id: G8JM14
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2044
gene id: 931890:Ecym_2044
uniprot id: G8JP01
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

931890:Ecym 3071
gene id: 931890:Ecym_3071
uniprot id: G8JR14
names: Function
messages: Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
messages: Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.

931890:Ecym 3212
gene id: 931890:Ecym_3212
uniprot id: G8JRE1
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 3 family.

931890:Ecym 7334
gene id: 931890:Ecym_7334
uniprot id: G8JWF1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 3608
gene id: 931890:Ecym_3608
uniprot id: G8JQT6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SCO1/2 family.
messages: Mitochondrion inner membrane

931890:Ecym 1263
gene id: 931890:Ecym_1263
uniprot id: G8JN41
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5004
gene id: 931890:Ecym_5004
uniprot id: I6NCL5
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931890:Ecym 6094
gene id: 931890:Ecym_6094
uniprot id: G8JV11
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC24 family.
messages: Component of the NDC80 complex.
messages: Nucleus
messages: kinetochore

931890:Ecym 2116
gene id: 931890:Ecym_2116
uniprot id: G8JPM0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom40 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 1293
gene id: 931890:Ecym_1293
uniprot id: G8JN68
names: Similarity
messages: Belongs to the WD repeat LST8 family.

931890:Ecym 7010
gene id: 931890:Ecym_7010
uniprot id: G8JVK3
names: Similarity
messages: Belongs to the CDC73 family.

931890:Ecym 6436
gene id: 931890:Ecym_6436
uniprot id: G8JUM7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4312
gene id: 931890:Ecym_4312
uniprot id: G8JTM2
names: Function
names: Similarity
messages: Belongs to the actin family. ARP6 subfamily.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability.

931890:Ecym 4595
gene id: 931890:Ecym_4595
uniprot id: G8JSA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
messages: Membrane

931890:Ecym 8286
gene id: 931890:Ecym_8286
uniprot id: G8JXJ2
names: Function
names: Similarity
messages: Belongs to the adenylyl cyclase class-3 family.
messages: Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP.

931890:Ecym 5297
gene id: 931890:Ecym_5297
uniprot id: I6NDB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 37 family.

931890:Ecym 1199
gene id: 931890:Ecym_1199
uniprot id: G8JMY3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM34 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

931890:Ecym 8173
gene id: 931890:Ecym_8173
uniprot id: G8JX85
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 2329
gene id: 931890:Ecym_2329
uniprot id: G8JQ66
names: Similarity
messages: Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

931890:Ecym 2212
gene id: 931890:Ecym_2212
uniprot id: G8JP56
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1345
gene id: 931890:Ecym_1345
uniprot id: G8JNB5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 7045
gene id: 931890:Ecym_7045
uniprot id: G8JVN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5110
gene id: 931890:Ecym_5110
uniprot id: I6NCU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 7326
gene id: 931890:Ecym_7326
uniprot id: G8JWE5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SNF8 family.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).

931890:Ecym 6278
gene id: 931890:Ecym_6278
uniprot id: G8JVH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the esterase D family.
messages: Cytoplasm
messages: Serine hydrolase involved in the detoxification of formaldehyde.

931890:Ecym 7073
gene id: 931890:Ecym_7073
uniprot id: G8JVR1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP4 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 5335
gene id: 931890:Ecym_5335
uniprot id: I6NDF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo5/eukaryotic RPB5 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 8073
gene id: 931890:Ecym_8073
uniprot id: G8JWZ5
names: Function
names: Similarity
messages: Belongs to the tubulin family.
messages: Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome.

931890:Ecym 2580
gene id: 931890:Ecym_2580
uniprot id: G8JQG3
names: Function
names: Similarity
messages: Belongs to the IRC6 family.
messages: Involved in gross chromosomal rearrangements (GCRs) and telomere healing.

931890:Ecym 5333
gene id: 931890:Ecym_5333
uniprot id: I6NDF0
names: Similarity
messages: Belongs to the TAF9 family. CENP-S/MHF1 subfamily.

931890:Ecym 6423
gene id: 931890:Ecym_6423
uniprot id: G8JUL5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat IPI3/WDR18 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

931890:Ecym 3260
gene id: 931890:Ecym_3260
uniprot id: G8JRI4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

931890:Ecym 5466
gene id: 931890:Ecym_5466
uniprot id: I6NDS2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8270
gene id: 931890:Ecym_8270
uniprot id: G8JXH8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CBF/MAK21 family.
messages: Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm.
messages: nucleolus

931890:Ecym 5562
gene id: 931890:Ecym_5562
uniprot id: I6NE09
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the polyadenylate-binding protein type-1 family.
messages: Binds the poly(A) tail of mRNA.
messages: Cytoplasm

931890:Ecym 3215
gene id: 931890:Ecym_3215
uniprot id: G8JRE3
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 5198
gene id: 931890:Ecym_5198
uniprot id: I6ND27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS21 family.
messages: Component of the small ribosomal subunit.
messages: Cytoplasm
messages: Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability.

931890:Ecym 3008
gene id: 931890:Ecym_3008
uniprot id: G8JQV8
names: Similarity
messages: Belongs to the eukaryotic ATPase epsilon family.

931890:Ecym 7369
gene id: 931890:Ecym_7369
uniprot id: G8JWI0
names: Domain
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the DENR family.
messages: Cytoplasm
messages: Interacts with the 40S ribosomal subunit.
messages: The SUI1 domain may be involved in RNA binding.

931890:Ecym 2332
gene id: 931890:Ecym_2332
uniprot id: G8JQ69
names: Similarity
messages: Belongs to the SecY/SEC61-alpha family.

931890:Ecym 2560
gene id: 931890:Ecym_2560
uniprot id: G8JQC1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INCENP family.
messages: Nucleus
messages: spindle

931890:Ecym 3534
gene id: 931890:Ecym_3534
uniprot id: G8JQM7
names: Similarity
messages: Belongs to the activator 1 small subunits family.

931890:Ecym 7082
gene id: 931890:Ecym_7082
uniprot id: G8JVS0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NPL4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Nucleus membrane
messages: perinuclear region

931890:Ecym 2311
gene id: 931890:Ecym_2311
uniprot id: G8JQ51
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus
messages: Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex.

931890:Ecym 6428
gene id: 931890:Ecym_6428
uniprot id: G8JUL9
names: Similarity
messages: Belongs to the peptidase M67A family. CSN5 subfamily.

931890:Ecym 2333
gene id: 931890:Ecym_2333
uniprot id: G8JQ70
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic12 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

931890:Ecym 3225
gene id: 931890:Ecym_3225
uniprot id: G8JRF3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM5 / TYW2 family.
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM5/TYW2 family.
messages: Cytoplasm
messages: Mitochondrion matrix
messages: Monomer.
messages: Nucleus
messages: Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding.

931890:Ecym 4684
gene id: 931890:Ecym_4684
uniprot id: G8JSI3
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

931890:Ecym 2317
gene id: 931890:Ecym_2317
uniprot id: G8JQ57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 5629
gene id: 931890:Ecym_5629
uniprot id: I6NE73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the INP2 family.
messages: Membrane
messages: Peroxisome membrane

931890:Ecym 8282
gene id: 931890:Ecym_8282
uniprot id: G8JXJ0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MMM1 family.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Homodimer. Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.

931890:Ecym 2664
gene id: 931890:Ecym_2664
uniprot id: G8JNU9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 3238
gene id: 931890:Ecym_3238
uniprot id: G8JRG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the LOT5 family.
messages: Nucleus

931890:Ecym 3620
gene id: 931890:Ecym_3620
uniprot id: G8JQU7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4260
gene id: 931890:Ecym_4260
uniprot id: G8JTH1
names: Similarity
messages: Belongs to the SLX4 family.

931890:Ecym 7070
gene id: 931890:Ecym_7070
uniprot id: G8JVQ8
names: Similarity
messages: Belongs to the MGR2 family.

931890:Ecym 3201
gene id: 931890:Ecym_3201
uniprot id: G8JRD1
names: Function
names: Similarity
messages: Belongs to the cyclophilin-type PPIase family.
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 3300
gene id: 931890:Ecym_3300
uniprot id: G8JRM3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC24 subfamily.
messages: Cytoplasm

931890:Ecym 7114
gene id: 931890:Ecym_7114
uniprot id: G8JVV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.
messages: Cytoplasm

931890:Ecym 5196
gene id: 931890:Ecym_5196
uniprot id: I6ND25
names: Function
names: Similarity
messages: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
messages: Belongs to the DEAD box helicase family. eIF4A subfamily.

931890:Ecym 2585
gene id: 931890:Ecym_2585
uniprot id: G8JQG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 6258
gene id: 931890:Ecym_6258
uniprot id: G8JVG1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 6088
gene id: 931890:Ecym_6088
uniprot id: G8JV05
names: Similarity
messages: Belongs to the syntaxin family.

931890:Ecym 3040
gene id: 931890:Ecym_3040
uniprot id: G8JQY5
names: Function
names: Similarity
names: Subunit
messages: Belongs to the COQ10 family.
messages: Interacts with coenzyme Q.
messages: Required for the function of coenzyme Q in the respiratory chain. May serve as a chaperone or may be involved in the transport of Q6 from its site of synthesis to the catalytic sites of the respiratory complexes.

931890:Ecym 3446
gene id: 931890:Ecym_3446
uniprot id: G8JS12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIM1 family.
messages: Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis.
messages: Nucleus

931890:Ecym 5276
gene id: 931890:Ecym_5276
uniprot id: I6ND97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SDHAF2 family.
messages: Interacts with the flavoprotein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.

931890:Ecym 5086
gene id: 931890:Ecym_5086
uniprot id: I6NCT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELP5 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 2821
gene id: 931890:Ecym_2821
uniprot id: G8JQF4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

931890:Ecym 4733
gene id: 931890:Ecym_4733
uniprot id: G8JSM9
names: Similarity
messages: Belongs to the DNA polymerase delta/II small subunit family.

931890:Ecym 6116
gene id: 931890:Ecym_6116
uniprot id: G8JV30
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 6486
gene id: 931890:Ecym_6486
uniprot id: G8JUS4
names: Similarity
messages: Belongs to the peptidase S8 family. Furin subfamily.

931890:Ecym 3237
gene id: 931890:Ecym_3237
uniprot id: G8JRG2
names: Similarity
messages: Belongs to the Orn/Lys/Arg decarboxylase class-II family.

931890:Ecym 4618
gene id: 931890:Ecym_4618
uniprot id: G8JSC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the AEP2 family.
messages: Binds to the 5'UTR of the OLI1 mRNA.
messages: Mitochondrion
messages: Required for translation of the mitochondrial OLI1 transcript coding for the mitochondrial ATP synthase subunit 9.

931890:Ecym 4362
gene id: 931890:Ecym_4362
uniprot id: G8JTR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG28 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 3613
gene id: 931890:Ecym_3613
uniprot id: G8JQU0
names: Similarity
messages: Belongs to the ubiquitin-activating E1 family.

931890:Ecym 1317
gene id: 931890:Ecym_1317
uniprot id: G8JN88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 4375
gene id: 931890:Ecym_4375
uniprot id: G8JTS7
names: Similarity
messages: Belongs to the complex I LYR family.

931890:Ecym 2728
gene id: 931890:Ecym_2728
uniprot id: G8JPG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

931890:Ecym 6113
gene id: 931890:Ecym_6113
uniprot id: G8JV28
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SUA5 family.
messages: Cytoplasm
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.

931890:Ecym 8053
gene id: 931890:Ecym_8053
uniprot id: G8JWX5
names: Similarity
messages: Belongs to the Rho GDI family.

931890:Ecym 6374
gene id: 931890:Ecym_6374
uniprot id: G8JUG9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

931890:Ecym 4062
gene id: 931890:Ecym_4062
uniprot id: G8JSY9
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

931890:Ecym 8406
gene id: 931890:Ecym_8406
uniprot id: G8JXV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat PRP19 family.
messages: Homotetramer.
messages: Nucleus
messages: Ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome.

931890:Ecym 5213
gene id: 931890:Ecym_5213
uniprot id: I6ND40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TRM61 family.
messages: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
messages: Nucleus

931890:Ecym 5485
gene id: 931890:Ecym_5485
uniprot id: I6NDT8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I).
messages: Belongs to the NDUFAF7 family.
messages: Mitochondrion

931890:Ecym 1441
gene id: 931890:Ecym_1441
uniprot id: G8JMF0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SWC4 family.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

931890:Ecym 6457
gene id: 931890:Ecym_6457
uniprot id: G8JUP8
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 2530
gene id: 931890:Ecym_2530
uniprot id: G8JQ93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adenosyl-L-methionine (AdoMet)-dependent tRNA (uracil-O(2)-)-methyltransferase.
messages: Belongs to the TRM44 family.
messages: Cytoplasm

931890:Ecym 5624
gene id: 931890:Ecym_5624
uniprot id: I6NE68
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.

931890:Ecym 4066
gene id: 931890:Ecym_4066
uniprot id: G8JSZ3
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

931890:Ecym 3584
gene id: 931890:Ecym_3584
uniprot id: G8JQR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GINS4/SLD5 family.
messages: Nucleus
messages: The GINS complex plays an essential role in the initiation of DNA replication.

931890:Ecym 4611
gene id: 931890:Ecym_4611
uniprot id: G8JSB8
names: Similarity
messages: Belongs to the phosphohexose mutase family.

931890:Ecym 3135
gene id: 931890:Ecym_3135
uniprot id: G8JR70
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 7089
gene id: 931890:Ecym_7089
uniprot id: G8JVS6
names: Subunit
messages: Homodimer.

931890:Ecym 8302
gene id: 931890:Ecym_8302
uniprot id: G8JXK6
names: Similarity
messages: Belongs to the NOC2 family.

931890:Ecym 3001
gene id: 931890:Ecym_3001
uniprot id: G8JQV1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8335
gene id: 931890:Ecym_8335
uniprot id: G8JXN9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4347
gene id: 931890:Ecym_4347
uniprot id: G8JTQ5
names: Similarity
messages: Belongs to the aspartokinase family.

931890:Ecym 4246
gene id: 931890:Ecym_4246
uniprot id: G8JTF8
names: Similarity
messages: Belongs to the dopey family.

931890:Ecym 2003
gene id: 931890:Ecym_2003
uniprot id: G8JNF3
names: Similarity
messages: Belongs to the DCP1 family.

931890:Ecym 6196
gene id: 931890:Ecym_6196
uniprot id: G8JVA0
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

931890:Ecym 3107
gene id: 931890:Ecym_3107
uniprot id: G8JR46
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

931890:Ecym 5392
gene id: 931890:Ecym_5392
uniprot id: I6NDK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom7 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 8059
gene id: 931890:Ecym_8059
uniprot id: G8JWY1
names: Similarity
messages: Belongs to the UPP synthase family.

931890:Ecym 8272
gene id: 931890:Ecym_8272
uniprot id: G8JXI0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 2774
gene id: 931890:Ecym_2774
uniprot id: G8JQ10
names: Similarity
messages: Belongs to the FBPase class 1 family.

931890:Ecym 3249
gene id: 931890:Ecym_3249
uniprot id: G8JRH3
names: Function
names: Similarity
messages: Belongs to the dus family.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.

931890:Ecym 5613
gene id: 931890:Ecym_5613
uniprot id: I6NE57
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP14 family.
messages: Cytoplasm

931890:Ecym 5622
gene id: 931890:Ecym_5622
uniprot id: I6NE66
names: Similarity
messages: Belongs to the ATG16 family.

931890:Ecym 5242
gene id: 931890:Ecym_5242
uniprot id: I6ND67
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3270
gene id: 931890:Ecym_3270
uniprot id: G8JRJ4
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 3087
gene id: 931890:Ecym_3087
uniprot id: G8JR28
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

931890:Ecym 3456
gene id: 931890:Ecym_3456
uniprot id: G8JS21
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CNOT2/3/5 family.
messages: Nucleus

931890:Ecym 4620
gene id: 931890:Ecym_4620
uniprot id: G8JSC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ku70 family.
messages: Nucleus
messages: telomere

931890:Ecym 6473
gene id: 931890:Ecym_6473
uniprot id: G8JUR4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SSU72 phosphatase family.
messages: Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs.
messages: Component of the cleavage and polyadenylation factor (CPF) complex.
messages: Nucleus
messages: Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).

931890:Ecym 3568
gene id: 931890:Ecym_3568
uniprot id: G8JQQ5
names: Similarity
messages: Belongs to the NAD kinase family.

931890:Ecym 4232
gene id: 931890:Ecym_4232
uniprot id: G8JTE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SAC3 family.
messages: Nucleus envelope

931890:Ecym 3562
gene id: 931890:Ecym_3562
uniprot id: G8JQP9
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
messages: Binds 1 FAD per monomer.
messages: Irreversibly catalyzes the reduction of fumarate to succinate.

931890:Ecym 3619
gene id: 931890:Ecym_3619
uniprot id: G8JQU6
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 2158
gene id: 931890:Ecym_2158
uniprot id: G8JNJ4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Fungal fatty acid synthetase subunit alpha family.

931890:Ecym 2520
gene id: 931890:Ecym_2520
uniprot id: G8JQ83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate.
messages: Mitochondrion inner membrane

931890:Ecym 6367
gene id: 931890:Ecym_6367
uniprot id: G8JUG3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.
messages: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.

931890:Ecym 2788
gene id: 931890:Ecym_2788
uniprot id: G8JQ23
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane
messages: O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway.

931890:Ecym 8096
gene id: 931890:Ecym_8096
uniprot id: G8JX16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS25 family.
messages: Mitochondrion

931890:Ecym 5515
gene id: 931890:Ecym_5515
uniprot id: I6NDW5
names: Function
names: Similarity
messages: Belongs to the BLOC1S4 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1), a complex that is involved in endosomal cargo sorting.

931890:Ecym 8425
gene id: 931890:Ecym_8425
uniprot id: G8JXX0
names: Similarity
messages: Belongs to the multicopper oxidase family.

931890:Ecym 7328
gene id: 931890:Ecym_7328
uniprot id: G8JWE7
names: Similarity
messages: Belongs to the LOC1 family.

931890:Ecym 4380
gene id: 931890:Ecym_4380
uniprot id: G8JTT2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tim44 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion inner membrane

931890:Ecym 6169
gene id: 931890:Ecym_6169
uniprot id: G8JV75
names: Similarity
messages: Belongs to the WD repeat CDC20/Fizzy family.

931890:Ecym 3079
gene id: 931890:Ecym_3079
uniprot id: G8JR22
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDS23 family.
messages: Cytoplasm
messages: Involved in DNA replication and cell separation.

931890:Ecym 5023
gene id: 931890:Ecym_5023
uniprot id: I6NCN2
names: Similarity
messages: Belongs to the BolA/IbaG family.

931890:Ecym 3092
gene id: 931890:Ecym_3092
uniprot id: G8JR32
names: Function
messages: Cleaves the gamma-glutamyl peptide bond of glutathione and glutathione conjugates.

931890:Ecym 4498
gene id: 931890:Ecym_4498
uniprot id: G8JU34
names: Similarity
messages: Belongs to the proteasome subunit p27 family.

931890:Ecym 4191
gene id: 931890:Ecym_4191
uniprot id: G8JTB4
names: Similarity
messages: Belongs to the peptidase M16 family.

931890:Ecym 2709
gene id: 931890:Ecym_2709
uniprot id: G8JPE8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase U48 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 3492
gene id: 931890:Ecym_3492
uniprot id: G8JS54
names: Similarity
messages: Belongs to the small Tim family.

931890:Ecym 5229
gene id: 931890:Ecym_5229
uniprot id: I6ND55
names: Similarity
messages: Belongs to the SUN family.

931890:Ecym 8358
gene id: 931890:Ecym_8358
uniprot id: G8JXQ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family. DDX52/ROK1 subfamily.
messages: nucleolus

931890:Ecym 2260
gene id: 931890:Ecym_2260
uniprot id: G8JPQ1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the HDDC2 family.
messages: Catalyzes the dephosphorylation of the nucleoside 5'-monophosphates deoxyadenosine monophosphate (dAMP), deoxycytidine monophosphate (dCMP), deoxyguanosine monophosphate (dGMP) and deoxythymidine monophosphate (dTMP).
messages: Homodimer.

931890:Ecym 7025
gene id: 931890:Ecym_7025
uniprot id: G8JVL7
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 7223
gene id: 931890:Ecym_7223
uniprot id: G8JW54
names: Similarity
messages: Belongs to the XPC family.

931890:Ecym 1506
gene id: 931890:Ecym_1506
uniprot id: G8JMR5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the bZIP family.
messages: Nucleus

931890:Ecym 6312
gene id: 931890:Ecym_6312
uniprot id: G8JUB1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GINS2/PSF2 family.
messages: Component of the GINS complex.
messages: Nucleus

931890:Ecym 3427
gene id: 931890:Ecym_3427
uniprot id: G8JRZ4
names: Similarity
messages: Belongs to the multicopper oxidase family.

931890:Ecym 2344
gene id: 931890:Ecym_2344
uniprot id: G8JQ77
names: Similarity
messages: Belongs to the GCN1 family.

931890:Ecym 3586
gene id: 931890:Ecym_3586
uniprot id: G8JQR9
names: Similarity
messages: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

931890:Ecym 4098
gene id: 931890:Ecym_4098
uniprot id: G8JT24
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS17 family.

931890:Ecym 5170
gene id: 931890:Ecym_5170
uniprot id: I6ND02
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

931890:Ecym 3174
gene id: 931890:Ecym_3174
uniprot id: G8JRA6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PA-phosphatase related phosphoesterase family.
messages: Membrane

931890:Ecym 4555
gene id: 931890:Ecym_4555
uniprot id: G8JU87
names: Similarity
messages: Belongs to the thiamine pyrophosphokinase family.

931890:Ecym 4609
gene id: 931890:Ecym_4609
uniprot id: G8JSB6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF8 family.
messages: Nucleus

931890:Ecym 2659
gene id: 931890:Ecym_2659
uniprot id: G8JNU5
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

931890:Ecym 6402
gene id: 931890:Ecym_6402
uniprot id: G8JUJ6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CHS7 family.
messages: Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum.
messages: Interacts with CHS3.

931890:Ecym 8390
gene id: 931890:Ecym_8390
uniprot id: G8JXT6
names: Similarity
messages: Belongs to the WrbA family.

931890:Ecym 4181
gene id: 931890:Ecym_4181
uniprot id: G8JTA4
names: Similarity
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eS31 family.
messages: In the N-terminal section; belongs to the ubiquitin family.

931890:Ecym 7266
gene id: 931890:Ecym_7266
uniprot id: G8JW95
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

931890:Ecym 4695
gene id: 931890:Ecym_4695
uniprot id: G8JSJ3
names: Similarity
messages: Belongs to the RICTOR family.

931890:Ecym 2413
gene id: 931890:Ecym_2413
uniprot id: G8JP87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

931890:Ecym 8415
gene id: 931890:Ecym_8415
uniprot id: G8JXW0
names: Similarity
messages: Belongs to the FGGY kinase family.

931890:Ecym 5497
gene id: 931890:Ecym_5497
uniprot id: I6NDU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

931890:Ecym 2473
gene id: 931890:Ecym_2473
uniprot id: G8JPU0
names: Similarity
messages: Belongs to the RRN3 family.

931890:Ecym 7158
gene id: 931890:Ecym_7158
uniprot id: G8JVZ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2214
gene id: 931890:Ecym_2214
uniprot id: G8JP58
names: Function
messages: Delta(8)-fatty-acid desaturase which introduces a double bond at the 8-position in the long-chain base (LCB) of ceramides. Required for the formation of the di-unsaturated sphingoid base (E,E)-sphinga-4,8-dienine during glucosylceramide (GluCer) biosynthesis.

931890:Ecym 5206
gene id: 931890:Ecym_5206
uniprot id: I6ND33
names: Similarity
messages: In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily.

931890:Ecym 4777
gene id: 931890:Ecym_4777
uniprot id: G8JSR7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. BUD32 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: telomere

931890:Ecym 2492
gene id: 931890:Ecym_2492
uniprot id: G8JPV6
names: Similarity
messages: Belongs to the pyridoxine kinase family.

931890:Ecym 2644
gene id: 931890:Ecym_2644
uniprot id: G8JNT1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 15 family.
messages: Nucleus

931890:Ecym 6390
gene id: 931890:Ecym_6390
uniprot id: G8JUI5
names: Function
names: Similarity
messages: Belongs to the endosulfine family.
messages: Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway.

931890:Ecym 3526
gene id: 931890:Ecym_3526
uniprot id: G8JQM0
names: Similarity
messages: Belongs to the MON2 family.

931890:Ecym 8106
gene id: 931890:Ecym_8106
uniprot id: G8JX26
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3311
gene id: 931890:Ecym_3311
uniprot id: G8JRN3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the peripheral membrane COG complex that is involved in intra-Golgi protein trafficking. COG is located at the cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles and possibly a number of other membrane trafficking events.
messages: Belongs to the COG6 family.
messages: Component of the conserved oligomeric Golgi complex.
messages: Golgi apparatus membrane
messages: Membrane

931890:Ecym 2758
gene id: 931890:Ecym_2758
uniprot id: G8JPZ4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7362
gene id: 931890:Ecym_7362
uniprot id: G8JWH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5' to 3' DNA replicative helicase recruited to paused replisomes to promote fork progression throughout nonhistone protein-DNA complexes, naturally occurring impediments that are encountered in each S phase where replication forks pauses. Required for timely replication of the telomere and subtelomeric DNA and for wild-type levels of telomeric silencing. Involved in DNA repair during stalled replication fork, regulation of fragile sites expression and essential for genome stability. Plays also a role in mtDNA replication. Has G-quadruplex (G4) unwinding activity and can suppress G4-induced genome instability when PIF1 levels are low.
messages: Belongs to the helicase family. PIF1 subfamily.
messages: Nucleus
messages: telomere

931890:Ecym 7454
gene id: 931890:Ecym_7454
uniprot id: G8JWQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.
messages: Mitochondrion matrix

931890:Ecym 5330
gene id: 931890:Ecym_5330
uniprot id: I6NDE7
names: Similarity
names: Subunit
messages: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
messages: Homotetramer.

931890:Ecym 4394
gene id: 931890:Ecym_4394
uniprot id: G8JTU5
names: Similarity
messages: Belongs to the peptidase A1 family.

931890:Ecym 7306
gene id: 931890:Ecym_7306
uniprot id: G8JWC8
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

931890:Ecym 3333
gene id: 931890:Ecym_3333
uniprot id: G8JRQ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclin family. Cyclin C subfamily.
messages: Nucleus

931890:Ecym 7226
gene id: 931890:Ecym_7226
uniprot id: G8JW57
names: Similarity
messages: Belongs to the R-transferase family.

931890:Ecym 3313
gene id: 931890:Ecym_3313
uniprot id: G8JRN5
names: Function
names: Similarity
messages: Belongs to the beta-class carbonic anhydrase family.
messages: Reversible hydration of carbon dioxide.

931890:Ecym 4420
gene id: 931890:Ecym_4420
uniprot id: G8JTW6
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3140
gene id: 931890:Ecym_3140
uniprot id: G8JR75
names: Similarity
messages: Belongs to the chaperonin (HSP60) family.

931890:Ecym 2751
gene id: 931890:Ecym_2751
uniprot id: G8JPY7
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

931890:Ecym 8170
gene id: 931890:Ecym_8170
uniprot id: G8JX82
names: Similarity
messages: Belongs to the PP2C family.

931890:Ecym 2738
gene id: 931890:Ecym_2738
uniprot id: G8JPH1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs.
messages: Nucleus

931890:Ecym 8128
gene id: 931890:Ecym_8128
uniprot id: G8JX45
names: Similarity
messages: Belongs to the MNN1/MNT family.

931890:Ecym 2667
gene id: 931890:Ecym_2667
uniprot id: G8JNV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ALG14 family.
messages: Endoplasmic reticulum membrane
messages: Heterodimer with ALG13 to form a functional enzyme.
messages: Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER.
messages: Membrane
messages: Nucleus membrane

931890:Ecym 2382
gene id: 931890:Ecym_2382
uniprot id: G8JNP7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Clp1 family. Clp1 subfamily.
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.
messages: Component of a pre-mRNA cleavage factor complex. Interacts directly with PCF11.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May lack the polyribonucleotide 5'-hydroxyl-kinase and polynucleotide 5'-hydroxyl-kinase activities that are characteristic of the human ortholog.
messages: Nucleus
messages: Required for endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.

931890:Ecym 3025
gene id: 931890:Ecym_3025
uniprot id: G8JQX2
names: Similarity
messages: Belongs to the SGT family.

931890:Ecym 3450
gene id: 931890:Ecym_3450
uniprot id: G8JS16
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

931890:Ecym 1337
gene id: 931890:Ecym_1337
uniprot id: G8JNA7
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
messages: One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.

931890:Ecym 2400
gene id: 931890:Ecym_2400
uniprot id: G8JNR5
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

931890:Ecym 4160
gene id: 931890:Ecym_4160
uniprot id: G8JT84
names: Function
names: Similarity
messages: Belongs to the LipB family.
messages: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.

931890:Ecym 2025
gene id: 931890:Ecym_2025
uniprot id: G8JNY4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1527
gene id: 931890:Ecym_1527
uniprot id: G8JMT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 14 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 7193
gene id: 931890:Ecym_7193
uniprot id: G8JW26
names: Similarity
messages: Belongs to the proteasome subunit S3 family.

931890:Ecym 4758
gene id: 931890:Ecym_4758
uniprot id: G8JSP9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2197
gene id: 931890:Ecym_2197
uniprot id: G8JP41
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family.
messages: Endoplasmic reticulum membrane
messages: Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate.

931890:Ecym 4003
gene id: 931890:Ecym_4003
uniprot id: G8JST4
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

931890:Ecym 4123
gene id: 931890:Ecym_4123
uniprot id: G8JT49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 3468
gene id: 931890:Ecym_3468
uniprot id: G8JS32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM3 family.
messages: Membrane raft

931890:Ecym 4587
gene id: 931890:Ecym_4587
uniprot id: G8JS98
names: Similarity
messages: Belongs to the polyprenol kinase family.

931890:Ecym 3444
gene id: 931890:Ecym_3444
uniprot id: G8JS10
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4714
gene id: 931890:Ecym_4714
uniprot id: G8JSL2
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane
messages: Mitochondrion intermembrane space

931890:Ecym 4067
gene id: 931890:Ecym_4067
uniprot id: G8JSZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
messages: Belongs to the dynein light chain family.
messages: Cytoplasmic dynein consists of two catalytic heavy chains (HCs) and a number of non-catalytic subunits which present intermediate chains (ICs), light intermediate chains (LICs) and light chains (LCs).
messages: cytoskeleton
messages: nuclear pore complex

931890:Ecym 8261
gene id: 931890:Ecym_8261
uniprot id: G8JXG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

931890:Ecym 5331
gene id: 931890:Ecym_5331
uniprot id: I6NDE8
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931890:Ecym 7246
gene id: 931890:Ecym_7246
uniprot id: G8JW75
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FNT transporter (TC 2.A.44) family.
messages: Membrane

931890:Ecym 1208
gene id: 931890:Ecym_1208
uniprot id: G8JMZ1
names: Function
names: Similarity
messages: Belongs to the CHZ1 family.
messages: Forms a chaperone-bound H2A.Z-H2B complex that acts as a source for SWR1 complex-dependent H2A to H2A.Z histone replacement in chromatin.

931890:Ecym 1323
gene id: 931890:Ecym_1323
uniprot id: G8JN94
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 6217
gene id: 931890:Ecym_6217
uniprot id: G8JVC0
names: Similarity
messages: Belongs to the Clp1 family. NOL9/GRC3 subfamily.

931890:Ecym 7023
gene id: 931890:Ecym_7023
uniprot id: G8JVL5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the synaptobrevin family.
messages: Cell membrane
messages: Membrane

931890:Ecym 5295
gene id: 931890:Ecym_5295
uniprot id: I6NDB5
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2B family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 4092
gene id: 931890:Ecym_4092
uniprot id: G8JT18
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine/pyrimidine phosphoribosyltransferase family.
messages: Cytoplasm

931890:Ecym 1364
gene id: 931890:Ecym_1364
uniprot id: G8JND3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 6383
gene id: 931890:Ecym_6383
uniprot id: G8JUH8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

931890:Ecym 8111
gene id: 931890:Ecym_8111
uniprot id: G8JX31
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the G-protein coupled receptor 4 family.
messages: Membrane

931890:Ecym 2049
gene id: 931890:Ecym_2049
uniprot id: G8JP06
names: Function
messages: Catalytic subunit of an S-adenosyl-L-methionine-dependent tRNA methyltransferase complex that mediates the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs.

931890:Ecym 7182
gene id: 931890:Ecym_7182
uniprot id: G8JW15
names: Similarity
messages: Belongs to the yippee family.

931890:Ecym 2469
gene id: 931890:Ecym_2469
uniprot id: G8JPT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 7020
gene id: 931890:Ecym_7020
uniprot id: G8JVL2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Autophagy-specific protein that functions in response to autophagy-inducing signals as a scaffold to recruit other ATG proteins to organize preautophagosomal structure (PAS) formation. Modulates the timing and magnitude of the autophagy response, such as the size of the sequestering vesicles. Plays particularly a role in pexophagy and nucleophagy.
messages: Belongs to the ATG17 family.
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

931890:Ecym 2174
gene id: 931890:Ecym_2174
uniprot id: G8JNK9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import.
messages: Belongs to the peptidase S16 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Peroxisome matrix

931890:Ecym 1211
gene id: 931890:Ecym_1211
uniprot id: G8JMZ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase M24 family. SPT16 subfamily.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Component of the FACT complex.
messages: Nucleus

931890:Ecym 7075
gene id: 931890:Ecym_7075
uniprot id: G8JVR3
names: Function
names: Similarity
messages: Belongs to the PanB family.
messages: Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.

931890:Ecym 2203
gene id: 931890:Ecym_2203
uniprot id: G8JP47
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 5172
gene id: 931890:Ecym_5172
uniprot id: I6ND04
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the lunapark family.
messages: Endoplasmic reticulum membrane
messages: Plays a role in determining ER morphology.
messages: The C4-type zinc finger motif is necessary both for its ER three-way tubular junction localization and formation.

931890:Ecym 1485
gene id: 931890:Ecym_1485
uniprot id: G8JMJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG7 family.
messages: Mitochondrion

931890:Ecym 2334
gene id: 931890:Ecym_2334
uniprot id: G8JQ71
names: Similarity
messages: Belongs to the methyltransferase superfamily. NTM1 family.

931890:Ecym 8124
gene id: 931890:Ecym_8124
uniprot id: G8JX41
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GON7 family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. GON7 likely plays a supporting role to the catalytic subunit KAE1 in the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Nucleus

931890:Ecym 5488
gene id: 931890:Ecym_5488
uniprot id: I6NDU1
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 3111
gene id: 931890:Ecym_3111
uniprot id: G8JR50
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

931890:Ecym 4019
gene id: 931890:Ecym_4019
uniprot id: G8JSU9
names: Similarity
names: Subcellular Location Annotation
messages: Cytoplasm
messages: In the C-terminal section; belongs to the eukaryotic ribosomal protein eL40 family.
messages: In the N-terminal section; belongs to the ubiquitin family.
messages: Nucleus

931890:Ecym 2675
gene id: 931890:Ecym_2675
uniprot id: G8JNW0
names: Similarity
messages: Belongs to the peptidase M28 family.

931890:Ecym 1516
gene id: 931890:Ecym_1516
uniprot id: G8JMS3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the tubulin family.
messages: Dimer of alpha and beta chains. A typical microtubule is a hollow water-filled tube with an outer diameter of 25 nm and an inner diameter of 15 nM. Alpha-beta heterodimers associate head-to-tail to form protofilaments running lengthwise along the microtubule wall with the beta-tubulin subunit facing the microtubule plus end conferring a structural polarity. Microtubules usually have 13 protofilaments but different protofilament numbers can be found in some organisms and specialized cells.
messages: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin.

931890:Ecym 7409
gene id: 931890:Ecym_7409
uniprot id: G8JWM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP25 family.
messages: Mitochondrial mRNA stabilization factor.
messages: Mitochondrion inner membrane

931890:Ecym 6350
gene id: 931890:Ecym_6350
uniprot id: G8JUE6
names: Similarity
messages: Belongs to the glutamate--cysteine ligase type 3 family.

931890:Ecym 5204
gene id: 931890:Ecym_5204
uniprot id: I6ND31
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4741
gene id: 931890:Ecym_4741
uniprot id: G8JSN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: Cytoplasm
messages: nucleolus

931890:Ecym 6206
gene id: 931890:Ecym_6206
uniprot id: G8JVB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NASP family.
messages: Nucleus

931890:Ecym 4708
gene id: 931890:Ecym_4708
uniprot id: G8JSK6
names: Similarity
messages: Belongs to the serine/threonine dehydratase family.

931890:Ecym 2114
gene id: 931890:Ecym_2114
uniprot id: G8JPL8
names: Activity Regulation
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allosterically activated by ADP, AMP, or fructose 2,6-bisphosphate, and allosterically inhibited by ATP or citrate.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily.
messages: Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
messages: Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
messages: Cytoplasm
messages: Heterooctamer of 4 alpha and 4 beta chains.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931890:Ecym 3265
gene id: 931890:Ecym_3265
uniprot id: G8JRI9
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Binds 1 Mg(2+) or Mn(2+) ion per subunit.

931890:Ecym 6254
gene id: 931890:Ecym_6254
uniprot id: G8JVF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associates with 90S and pre-40S pre-ribosomal particles.
messages: Belongs to the RRP36 family.
messages: Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway.
messages: nucleolus

931890:Ecym 2261
gene id: 931890:Ecym_2261
uniprot id: G8JPQ2
names: Similarity
messages: Belongs to the universal ribosomal protein uL15 family.

931890:Ecym 3537
gene id: 931890:Ecym_3537
uniprot id: G8JQN0
names: Similarity
messages: Belongs to the CNOT9 family.

931890:Ecym 8324
gene id: 931890:Ecym_8324
uniprot id: G8JXM8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL18 family.
messages: Cytoplasm

931890:Ecym 3199
gene id: 931890:Ecym_3199
uniprot id: G8JRC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM24 family.
messages: Mitochondrion

931890:Ecym 5503
gene id: 931890:Ecym_5503
uniprot id: I6NDV4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BIG1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 6463
gene id: 931890:Ecym_6463
uniprot id: G8JUQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAP1 family.
messages: Homodimer.
messages: Involved in the regulation of telomere length, clustering and has a specific role in telomere position effect (TPE).
messages: Nucleus
messages: telomere

931890:Ecym 5224
gene id: 931890:Ecym_5224
uniprot id: I6ND50
names: Similarity
messages: Belongs to the glycosyl hydrolase 28 family.

931890:Ecym 7032
gene id: 931890:Ecym_7032
uniprot id: G8JVM4
names: Similarity
names: Subunit
messages: Belongs to the PPP phosphatase family. PP-2B subfamily.
messages: Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity.

931890:Ecym 5054
gene id: 931890:Ecym_5054
uniprot id: I6NCQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mis12 family.
messages: kinetochore

931890:Ecym 4158
gene id: 931890:Ecym_4158
uniprot id: G8JT82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC19 family.
messages: Nucleus
messages: kinetochore

931890:Ecym 3155
gene id: 931890:Ecym_3155
uniprot id: G8JR89
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

931890:Ecym 6190
gene id: 931890:Ecym_6190
uniprot id: G8JV94
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner.
messages: Belongs to the peptidase S16 family.
messages: Homohexamer or homoheptamer. Organized in a ring with a central cavity.
messages: Mitochondrion matrix

931890:Ecym 8355
gene id: 931890:Ecym_8355
uniprot id: G8JXQ4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 7005
gene id: 931890:Ecym_7005
uniprot id: G8JVJ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CAF1 family.
messages: Nucleus

931890:Ecym 7469
gene id: 931890:Ecym_7469
uniprot id: G8JWS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UTP23/FCF1 family. FCF1 subfamily.
messages: nucleolus

931890:Ecym 8055
gene id: 931890:Ecym_8055
uniprot id: G8JWX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ubiquitin conjugation factor E4 family.
messages: Cytoplasm

931890:Ecym 3168
gene id: 931890:Ecym_3168
uniprot id: G8JRA1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8202
gene id: 931890:Ecym_8202
uniprot id: G8JXB3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL35 family.

931890:Ecym 8411
gene id: 931890:Ecym_8411
uniprot id: G8JXV6
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
messages: Binds 1 [2Fe-2S] cluster.
messages: Binds 1 [3Fe-4S] cluster.
messages: Binds 1 [4Fe-4S] cluster.
messages: Component of complex II composed of four subunits: a flavoprotein (FP), an iron-sulfur protein (IP), and a cytochrome b composed of a large and a small subunit.
messages: Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).
messages: Mitochondrion inner membrane

931890:Ecym 5627
gene id: 931890:Ecym_5627
uniprot id: I6NE71
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

931890:Ecym 1082
gene id: 931890:Ecym_1082
uniprot id: G8JMD0
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 1148
gene id: 931890:Ecym_1148
uniprot id: G8JMP5
names: Function
names: Similarity
messages: Belongs to the dihydroxyacetone kinase (DAK) family.
messages: Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde.

931890:Ecym 6112
gene id: 931890:Ecym_6112
uniprot id: G8JV27
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 3184
gene id: 931890:Ecym_3184
uniprot id: G8JRB4
names: Function
names: Similarity
messages: Belongs to the RRF family.
messages: Necessary for protein synthesis in mitochondria. Functions as a ribosome recycling factor in mitochondria.

931890:Ecym 4471
gene id: 931890:Ecym_4471
uniprot id: G8JU08
names: Function
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Has a role in nuclear-cytoplasmic transport of proteins and mRNAs.
messages: Nucleus

931890:Ecym 4172
gene id: 931890:Ecym_4172
uniprot id: G8JT96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RuvB family.
messages: DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
messages: Nucleus

931890:Ecym 8018
gene id: 931890:Ecym_8018
uniprot id: G8JWU0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GAR1 family.
messages: Component of the small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs (H/ACA snoRNPs).
messages: Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
messages: nucleolus

931890:Ecym 4429
gene id: 931890:Ecym_4429
uniprot id: G8JTX3
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 8287
gene id: 931890:Ecym_8287
uniprot id: G8JXJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX17 family.
messages: Mitochondrion intermembrane space

931890:Ecym 8121
gene id: 931890:Ecym_8121
uniprot id: G8JX38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATP12 family.
messages: Mitochondrion

931890:Ecym 2391
gene id: 931890:Ecym_2391
uniprot id: G8JNQ6
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

931890:Ecym 8141
gene id: 931890:Ecym_8141
uniprot id: G8JX58
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8332
gene id: 931890:Ecym_8332
uniprot id: G8JXN6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NifU family.
messages: Mitochondrion matrix
messages: Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.

931890:Ecym 4242
gene id: 931890:Ecym_4242
uniprot id: G8JTF4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BBP/SF1 family.
messages: Necessary for the splicing of pre-mRNA. Has a role in the recognition of the branch site (5'-UACUAAC-3'), the pyrimidine tract and the 3'-splice site at the 3'-end of introns.
messages: Nucleus

931890:Ecym 3185
gene id: 931890:Ecym_3185
uniprot id: G8JRB5
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

931890:Ecym 3080
gene id: 931890:Ecym_3080
uniprot id: G8JR23
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Expected to bind 2 Fe(2+) ions per subunit.
messages: Membrane
messages: Stearoyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates.

931890:Ecym 8300
gene id: 931890:Ecym_8300
uniprot id: G8JXK4
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

931890:Ecym 4707
gene id: 931890:Ecym_4707
uniprot id: G8JSK5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

931890:Ecym 2581
gene id: 931890:Ecym_2581
uniprot id: G8JQG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMC4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 1110
gene id: 931890:Ecym_1110
uniprot id: G8JML0
names: Function
names: Similarity
messages: Belongs to the DPH4 family.
messages: Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2.

931890:Ecym 1442
gene id: 931890:Ecym_1442
uniprot id: G8JMF1
names: Similarity
messages: Belongs to the cullin family.

931890:Ecym 6145
gene id: 931890:Ecym_6145
uniprot id: G8JV57
names: Activity Regulation
names: Similarity
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.

931890:Ecym 2259
gene id: 931890:Ecym_2259
uniprot id: G8JPQ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 4 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 3434
gene id: 931890:Ecym_3434
uniprot id: G8JS01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE3 family.
messages: Endoplasmic reticulum membrane
messages: RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Required for the delivery of cortical endoplasmic reticulum into the emerging bud.

931890:Ecym 8413
gene id: 931890:Ecym_8413
uniprot id: G8JXV8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GOSR1 family.
messages: Component of several multiprotein Golgi SNARE complexes.
messages: Golgi apparatus membrane
messages: Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.
messages: Membrane

931890:Ecym 2043
gene id: 931890:Ecym_2043
uniprot id: G8JP00
names: Similarity
messages: Belongs to the universal ribosomal protein uS11 family.

931890:Ecym 4526
gene id: 931890:Ecym_4526
uniprot id: G8JU60
names: Similarity
messages: Belongs to the dpy-30 family.

931890:Ecym 2425
gene id: 931890:Ecym_2425
uniprot id: G8JP98
names: Similarity
messages: Belongs to the ISF1/MBR1 family.

931890:Ecym 2312
gene id: 931890:Ecym_2312
uniprot id: G8JQ52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

931890:Ecym 8158
gene id: 931890:Ecym_8158
uniprot id: G8JX71
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5221
gene id: 931890:Ecym_5221
uniprot id: I6ND47
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

931890:Ecym 2754
gene id: 931890:Ecym_2754
uniprot id: G8JPZ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. ECO subfamily.
messages: Nucleus

931890:Ecym 6420
gene id: 931890:Ecym_6420
uniprot id: G8JUL2
names: Similarity
messages: Belongs to the universal ribosomal protein uS3 family.

931890:Ecym 5373
gene id: 931890:Ecym_5373
uniprot id: I6NDI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

931890:Ecym 4505
gene id: 931890:Ecym_4505
uniprot id: G8JU39
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

931890:Ecym 8003
gene id: 931890:Ecym_8003
uniprot id: G8JXX3
names: Function
names: Similarity
messages: Belongs to the peptidase C13 family.
messages: Belongs to the peptidase C14B family.
messages: Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.

931890:Ecym 7408
gene id: 931890:Ecym_7408
uniprot id: G8JWL9
names: Similarity
messages: Belongs to the KTI12 family.

931890:Ecym 2352
gene id: 931890:Ecym_2352
uniprot id: G8JNL8
names: Similarity
messages: Belongs to the MCM family.

931890:Ecym 4076
gene id: 931890:Ecym_4076
uniprot id: G8JT03
names: Similarity
names: Subunit
messages: Belongs to the peptidase M16 family. PreP subfamily.
messages: Homodimer.

931890:Ecym 3415
gene id: 931890:Ecym_3415
uniprot id: G8JRY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

931890:Ecym 7477
gene id: 931890:Ecym_7477
uniprot id: G8JWS9
names: Similarity
messages: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

931890:Ecym 3336
gene id: 931890:Ecym_3336
uniprot id: G8JRQ7
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family.

931890:Ecym 6204
gene id: 931890:Ecym_6204
uniprot id: G8JVA8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family.
messages: Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 4585
gene id: 931890:Ecym_4585
uniprot id: G8JS96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC42 family.
messages: Forms a polymeric layer at the periphery of the spindle pole body (SPB) central plaque which has an essential function during SPB duplication and may facilitate attachment of the SPB to the nuclear membrane.
messages: spindle pole body

931890:Ecym 2087
gene id: 931890:Ecym_2087
uniprot id: G8JPJ1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS33 family.
messages: Mitochondrion

931890:Ecym 2503
gene id: 931890:Ecym_2503
uniprot id: G8JPW7
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

931890:Ecym 3422
gene id: 931890:Ecym_3422
uniprot id: G8JRY9
names: Function
names: Subcellular Location Annotation
messages: Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation-dependent pre-mRNA 3'-end formation.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 7220
gene id: 931890:Ecym_7220
uniprot id: G8JW51
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SLU7 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

931890:Ecym 6284
gene id: 931890:Ecym_6284
uniprot id: G8JVI5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL17 family.

931890:Ecym 6053
gene id: 931890:Ecym_6053
uniprot id: G8JUX7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

931890:Ecym 8410
gene id: 931890:Ecym_8410
uniprot id: G8JXV5
names: Function
names: Similarity
messages: Belongs to the VPS13 family.
messages: Mediates the transfer of lipids between membranes at organelle contact sites. May play a role in mitochondrial lipid homeostasis.

931890:Ecym 5067
gene id: 931890:Ecym_5067
uniprot id: I6NCR5
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

931890:Ecym 6474
gene id: 931890:Ecym_6474
uniprot id: G8JUR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase C54 family.
messages: Cytoplasm
messages: Nucleus
messages: Preautophagosomal structure
messages: Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

931890:Ecym 2242
gene id: 931890:Ecym_2242
uniprot id: G8JPN4
names: Similarity
messages: Belongs to the STXBP/unc-18/SEC1 family.

931890:Ecym 8326
gene id: 931890:Ecym_8326
uniprot id: G8JXN0
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

931890:Ecym 2034
gene id: 931890:Ecym_2034
uniprot id: G8JNZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 2 family.
messages: Nucleus

931890:Ecym 6242
gene id: 931890:Ecym_6242
uniprot id: G8JVE5
names: Similarity
messages: Belongs to the uroporphyrinogen-III synthase family.

931890:Ecym 1076
gene id: 931890:Ecym_1076
uniprot id: G8JMC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity.
messages: Belongs to the SPC25 family.
messages: Component of the NDC80 complex, which consists of NDC80, NUF2, SPC24 and SPC25.
messages: Nucleus
messages: kinetochore

931890:Ecym 3163
gene id: 931890:Ecym_3163
uniprot id: G8JR97
names: Similarity
messages: Belongs to the thymidylate kinase family.

931890:Ecym 5208
gene id: 931890:Ecym_5208
uniprot id: I6ND35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TrkH potassium transport family.
messages: Membrane

931890:Ecym 1198
gene id: 931890:Ecym_1198
uniprot id: G8JMY2
names: Similarity
messages: Belongs to the BolA/IbaG family.

931890:Ecym 3274
gene id: 931890:Ecym_3274
uniprot id: G8JRJ8
names: Similarity
messages: Belongs to the universal ribosomal protein uS14 family.

931890:Ecym 1447
gene id: 931890:Ecym_1447
uniprot id: G8JMF6
names: Similarity
messages: Belongs to the PRP18 family.

931890:Ecym 3179
gene id: 931890:Ecym_3179
uniprot id: G8JRB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding SRP family.
messages: Endoplasmic reticulum membrane

931890:Ecym 5056
gene id: 931890:Ecym_5056
uniprot id: I6NCQ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 8 family.
messages: Endoplasmic reticulum lumen

931890:Ecym 7165
gene id: 931890:Ecym_7165
uniprot id: G8JVZ8
names: Similarity
messages: Belongs to the VPS25 family.

931890:Ecym 7447
gene id: 931890:Ecym_7447
uniprot id: G8JWQ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: spindle

931890:Ecym 3277
gene id: 931890:Ecym_3277
uniprot id: G8JRK1
names: Similarity
messages: Belongs to the VAC14 family.

931890:Ecym 3330
gene id: 931890:Ecym_3330
uniprot id: G8JRQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KISH family.
messages: Golgi apparatus membrane
messages: Involved in the early part of the secretory pathway.
messages: Membrane

931890:Ecym 4404
gene id: 931890:Ecym_4404
uniprot id: G8JTV5
names: Similarity
messages: Belongs to the peptidase M16 family.

931890:Ecym 2598
gene id: 931890:Ecym_2598
uniprot id: G8JQH9
names: Similarity
messages: Belongs to the RMD1/sif2 family.

931890:Ecym 7230
gene id: 931890:Ecym_7230
uniprot id: G8JW61
names: Function
names: Similarity
messages: Belongs to the aconitase/IPM isomerase family.
messages: Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.

931890:Ecym 3284
gene id: 931890:Ecym_3284
uniprot id: G8JRK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
messages: nucleolus

931890:Ecym 6052
gene id: 931890:Ecym_6052
uniprot id: G8JUX6
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL13 family.

931890:Ecym 5404
gene id: 931890:Ecym_5404
uniprot id: I6NDL7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRT14 family.
messages: Involved in ribosome biogenesis, probably through modulation of rDNA transcription.
messages: nucleolus

931890:Ecym 1507
gene id: 931890:Ecym_1507
uniprot id: G8JMR6
names: Similarity
messages: Belongs to the oligoribonuclease family.

931890:Ecym 4701
gene id: 931890:Ecym_4701
uniprot id: G8JSJ9
names: Similarity
messages: Belongs to the PP2C family.

931890:Ecym 4116
gene id: 931890:Ecym_4116
uniprot id: G8JT42
names: Function
names: Similarity
names: Subunit
messages: Belongs to the CGI121/TPRKB family.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. CGI121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators. CGI121 is not required for tRNA modification.

931890:Ecym 2766
gene id: 931890:Ecym_2766
uniprot id: G8JQ02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

931890:Ecym 5294
gene id: 931890:Ecym_5294
uniprot id: I6NDB4
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 4087
gene id: 931890:Ecym_4087
uniprot id: G8JT13
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5064
gene id: 931890:Ecym_5064
uniprot id: I6NCR2
names: Similarity
messages: Belongs to the NSRP1 family.

931890:Ecym 3043
gene id: 931890:Ecym_3043
uniprot id: G8JQY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA 3'-terminal cyclase family. Type 2 subfamily.
messages: nucleolus

931890:Ecym 1287
gene id: 931890:Ecym_1287
uniprot id: G8JN62
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-II family.
messages: Functions in the biosynthesis of the anionic phospholipids phosphatidylglycerol and cardiolipin.
messages: Mitochondrion

931890:Ecym 7344
gene id: 931890:Ecym_7344
uniprot id: G8JWF9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5074
gene id: 931890:Ecym_5074
uniprot id: I6NCS2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

931890:Ecym 7168
gene id: 931890:Ecym_7168
uniprot id: G8JW01
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the Cu-Zn superoxide dismutase family.
messages: Binds 1 copper ion per subunit.
messages: Binds 1 zinc ion per subunit.
messages: Destroys radicals which are normally produced within the cells and which are toxic to biological systems.

931890:Ecym 3351
gene id: 931890:Ecym_3351
uniprot id: G8JRS0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily.
messages: Membrane
messages: Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix.
messages: Mitochondrion inner membrane

931890:Ecym 5137
gene id: 931890:Ecym_5137
uniprot id: I6NCX2
names: Similarity
messages: Belongs to the VPS54 family.

931890:Ecym 2475
gene id: 931890:Ecym_2475
uniprot id: G8JPU1
names: Similarity
messages: Belongs to the phosphohexose mutase family.

931890:Ecym 2362
gene id: 931890:Ecym_2362
uniprot id: G8JNM8
names: Function
names: Similarity
messages: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Belongs to the peptidase M67A family.

931890:Ecym 2396
gene id: 931890:Ecym_2396
uniprot id: G8JNR1
names: Similarity
messages: Belongs to the peptidase A1 family.

931890:Ecym 7352
gene id: 931890:Ecym_7352
uniprot id: G8JWG6
names: Similarity
messages: Belongs to the eukaryotic NMN adenylyltransferase family.

931890:Ecym 5461
gene id: 931890:Ecym_5461
uniprot id: I6NDR8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5633
gene id: 931890:Ecym_5633
uniprot id: I6NE77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Homodimer.
messages: Mitochondrion
messages: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.

931890:Ecym 4779
gene id: 931890:Ecym_4779
uniprot id: G8JSR9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2488
gene id: 931890:Ecym_2488
uniprot id: G8JPV2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BUD31 (G10) family.
messages: Nucleus

931890:Ecym 7386
gene id: 931890:Ecym_7386
uniprot id: G8JWJ7
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF beta-subunit/FixA family.
messages: Binds 1 AMP per subunit.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

931890:Ecym 5576
gene id: 931890:Ecym_5576
uniprot id: I6NE22
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1104
gene id: 931890:Ecym_1104
uniprot id: G8JMK5
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

931890:Ecym 5410
gene id: 931890:Ecym_5410
uniprot id: I6NDM2
names: Similarity
messages: Belongs to the syntaxin family.

931890:Ecym 5019
gene id: 931890:Ecym_5019
uniprot id: I6NCM8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 2328
gene id: 931890:Ecym_2328
uniprot id: G8JQ65
names: Function
names: Similarity
messages: Belongs to the LplA family.
messages: Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

931890:Ecym 2438
gene id: 931890:Ecym_2438
uniprot id: G8JPB0
names: Similarity
messages: Belongs to the universal ribosomal protein uS2 family.

931890:Ecym 2426
gene id: 931890:Ecym_2426
uniprot id: G8JP99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA2/NAM7 helicase family.
messages: Cytoplasm

931890:Ecym 5569
gene id: 931890:Ecym_5569
uniprot id: I6NE15
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SDA1 family.
messages: Required for 60S pre-ribosomal subunits export to the cytoplasm.
messages: nucleolus

931890:Ecym 5549
gene id: 931890:Ecym_5549
uniprot id: I6NDZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TBP family.
messages: Nucleus

931890:Ecym 5564
gene id: 931890:Ecym_5564
uniprot id: I6NE11
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

931890:Ecym 2309
gene id: 931890:Ecym_2309
uniprot id: G8JQ49
names: Similarity
messages: Belongs to the EIS1 family.

931890:Ecym 7275
gene id: 931890:Ecym_7275
uniprot id: G8JWA2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase F subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1).
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.
messages: Vacuole membrane

931890:Ecym 6118
gene id: 931890:Ecym_6118
uniprot id: G8JV32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

931890:Ecym 4424
gene id: 931890:Ecym_4424
uniprot id: G8JTX0
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VMA21 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Required for the assembly of the V0 complex of the vacuolar ATPase (V-ATPase) in the endoplasmic reticulum.

931890:Ecym 6059
gene id: 931890:Ecym_6059
uniprot id: G8JUY1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7118
gene id: 931890:Ecym_7118
uniprot id: G8JVV4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

931890:Ecym 5481
gene id: 931890:Ecym_5481
uniprot id: I6NDT5
names: Similarity
messages: Belongs to the precorrin methyltransferase family.

931890:Ecym 7077
gene id: 931890:Ecym_7077
uniprot id: G8JVR5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.

931890:Ecym 7260
gene id: 931890:Ecym_7260
uniprot id: G8JW89
names: Function
names: Similarity
messages: Belongs to the TFIIE alpha subunit family.
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

931890:Ecym 4540
gene id: 931890:Ecym_4540
uniprot id: G8JU73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 6241
gene id: 931890:Ecym_6241
uniprot id: G8JVE4
names: Subunit
messages: Homodimer.

931890:Ecym 2356
gene id: 931890:Ecym_2356
uniprot id: G8JNM2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat LIS1/nudF family.
messages: Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
messages: Self-associates. Interacts with NDL1 and dynein.
messages: cytoskeleton
messages: spindle pole

931890:Ecym 5472
gene id: 931890:Ecym_5472
uniprot id: I6NDS7
names: Similarity
messages: Belongs to the universal ribosomal protein uL11 family.

931890:Ecym 2620
gene id: 931890:Ecym_2620
uniprot id: G8JQK0
names: Similarity
messages: Belongs to the FUN14 family.

931890:Ecym 6107
gene id: 931890:Ecym_6107
uniprot id: G8JV22
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) ion per subunit.
messages: Binds 1 thiamine pyrophosphate per subunit.

931890:Ecym 4645
gene id: 931890:Ecym_4645
uniprot id: G8JSE6
names: Function
names: Similarity
messages: Belongs to the PNP/MTAP phosphorylase family.
messages: The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.

931890:Ecym 5099
gene id: 931890:Ecym_5099
uniprot id: I6NCU0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family. GCN5 subfamily.
messages: Nucleus

931890:Ecym 2733
gene id: 931890:Ecym_2733
uniprot id: G8JPG8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3190
gene id: 931890:Ecym_3190
uniprot id: G8JRC0
names: Similarity
messages: Belongs to the mitochondrion-specific ribosomal protein mL67 family.

931890:Ecym 3424
gene id: 931890:Ecym_3424
uniprot id: G8JRZ1
names: Similarity
messages: Belongs to the SEN15 family.

931890:Ecym 6183
gene id: 931890:Ecym_6183
uniprot id: G8JV87
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WRB/GET1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 1220
gene id: 931890:Ecym_1220
uniprot id: G8JN03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SKN1/KRE6 family.
messages: Membrane

931890:Ecym 8402
gene id: 931890:Ecym_8402
uniprot id: G8JXU8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MND1 family.
messages: Nucleus
messages: Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis.

931890:Ecym 1486
gene id: 931890:Ecym_1486
uniprot id: G8JMJ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 5498
gene id: 931890:Ecym_5498
uniprot id: I6NDU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat HIR1 family.
messages: Nucleus
messages: Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

931890:Ecym 8251
gene id: 931890:Ecym_8251
uniprot id: G8JXG0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 4630
gene id: 931890:Ecym_4630
uniprot id: G8JSD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 4053
gene id: 931890:Ecym_4053
uniprot id: G8JSY1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 6105
gene id: 931890:Ecym_6105
uniprot id: G8JV20
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SHE2 family.
messages: Nucleus

931890:Ecym 6051
gene id: 931890:Ecym_6051
uniprot id: G8JUX5
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

931890:Ecym 3121
gene id: 931890:Ecym_3121
uniprot id: G8JR56
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND1 (condensin subunit 1) family.
messages: Chromosome
messages: Nucleus
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

931890:Ecym 3224
gene id: 931890:Ecym_3224
uniprot id: G8JRF2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRP4 family.
messages: Cytoplasm

931890:Ecym 7181
gene id: 931890:Ecym_7181
uniprot id: G8JW14
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.

931890:Ecym 2666
gene id: 931890:Ecym_2666
uniprot id: G8JNV1
names: Similarity
names: Subunit
messages: Belongs to the triosephosphate isomerase family.
messages: Homodimer.

931890:Ecym 3077
gene id: 931890:Ecym_3077
uniprot id: G8JR20
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 3622
gene id: 931890:Ecym_3622
uniprot id: G8JQU9
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NMT1/THI5 family.
messages: Homodimer.
messages: Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme.

931890:Ecym 2811
gene id: 931890:Ecym_2811
uniprot id: G8JQE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC23/SEC24 family. SEC23 subfamily.
messages: COPII-coated vesicle membrane
messages: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Membrane

931890:Ecym 7367
gene id: 931890:Ecym_7367
uniprot id: G8JWH8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase subunit 5A family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Mitochondrion inner membrane

931890:Ecym 2813
gene id: 931890:Ecym_2813
uniprot id: G8JQE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family. SmF/LSm6 subfamily.
messages: Nucleus

931890:Ecym 5400
gene id: 931890:Ecym_5400
uniprot id: I6NDL3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 4549
gene id: 931890:Ecym_4549
uniprot id: G8JU81
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHE9 family.
messages: Homooligomer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion inner membrane
messages: Required for the maintenance of the structure of the mitochondrial inner membrane. Involved in mitochondrial morphology. Causes growth arrest when highly overexpressed.

931890:Ecym 4307
gene id: 931890:Ecym_4307
uniprot id: G8JTL7
names: Similarity
names: Subunit
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.
messages: Homodimer.

931890:Ecym 4557
gene id: 931890:Ecym_4557
uniprot id: G8JU88
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the succinate/malate CoA ligase alpha subunit family.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion
messages: Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.

931890:Ecym 4274
gene id: 931890:Ecym_4274
uniprot id: G8JTI5
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

931890:Ecym 1061
gene id: 931890:Ecym_1061
uniprot id: G8JMB0
names: Similarity
messages: Belongs to the phosphatidylethanolamine-binding protein family.

931890:Ecym 8142
gene id: 931890:Ecym_8142
uniprot id: G8JX59
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

931890:Ecym 4215
gene id: 931890:Ecym_4215
uniprot id: G8JTC9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS18 family.
messages: Membrane

931890:Ecym 7170
gene id: 931890:Ecym_7170
uniprot id: G8JW03
names: Caution
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERD2 family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 7028
gene id: 931890:Ecym_7028
uniprot id: G8JVM0
names: Similarity
messages: Belongs to the WD repeat coronin family.

931890:Ecym 3285
gene id: 931890:Ecym_3285
uniprot id: G8JRK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: Nucleus

931890:Ecym 2307
gene id: 931890:Ecym_2307
uniprot id: G8JQ47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone H3 family.
messages: Nucleus

931890:Ecym 1002
gene id: 931890:Ecym_1002
uniprot id: G8JM02
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2227
gene id: 931890:Ecym_2227
uniprot id: G8JP70
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3076
gene id: 931890:Ecym_3076
uniprot id: G8JR19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

931890:Ecym 2491
gene id: 931890:Ecym_2491
uniprot id: G8JPV5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC12 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Guanine nucleotide-exchange factor (GEF) required for the formation or budding of transport vesicles from the ER.

931890:Ecym 1248
gene id: 931890:Ecym_1248
uniprot id: G8JN27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5464
gene id: 931890:Ecym_5464
uniprot id: I6NDS1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the derlin family.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins.
messages: Membrane

931890:Ecym 4769
gene id: 931890:Ecym_4769
uniprot id: G8JSQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Nucleus

931890:Ecym 2250
gene id: 931890:Ecym_2250
uniprot id: G8JPP1
names: Function
names: Similarity
messages: Belongs to the HisA/HisF family.
messages: IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain.
messages: In the C-terminal section; belongs to the HisA/HisF family.

931890:Ecym 1284
gene id: 931890:Ecym_1284
uniprot id: G8JN59
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 4624
gene id: 931890:Ecym_4624
uniprot id: G8JSD0
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

931890:Ecym 6077
gene id: 931890:Ecym_6077
uniprot id: G8JUZ6
names: Similarity
messages: Belongs to the MYST (SAS/MOZ) family.

931890:Ecym 8031
gene id: 931890:Ecym_8031
uniprot id: G8JWV3
names: Similarity
messages: Belongs to the UPF0057 (PMP3) family.

931890:Ecym 7350
gene id: 931890:Ecym_7350
uniprot id: G8JWG4
names: Function
names: Similarity
messages: Belongs to the SNU71 family.
messages: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway.

931890:Ecym 8226
gene id: 931890:Ecym_8226
uniprot id: G8JXD7
names: Similarity
messages: Belongs to the peptidase S9B family.

931890:Ecym 4407
gene id: 931890:Ecym_4407
uniprot id: G8JTV7
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

931890:Ecym 6349
gene id: 931890:Ecym_6349
uniprot id: G8JUE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PI3/PI4-kinase family.
messages: Cell membrane
messages: Vacuole membrane

931890:Ecym 3310
gene id: 931890:Ecym_3310
uniprot id: G8JRN2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the DPH1/DPH2 family. DPH1 subfamily.
messages: Binds 1 [4Fe-4S] cluster per subunit. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the first step of diphthamide biosynthesis, a post-translational modification of histidine which occurs in elongation factor 2.

931890:Ecym 4591
gene id: 931890:Ecym_4591
uniprot id: G8JSA1
names: Similarity
messages: Belongs to the adaptor complexes medium subunit family.

931890:Ecym 1011
gene id: 931890:Ecym_1011
uniprot id: G8JM10
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M3 family.
messages: Binds 1 zinc ion.

931890:Ecym 5245
gene id: 931890:Ecym_5245
uniprot id: I6ND70
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M49 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 5644
gene id: 931890:Ecym_5644
uniprot id: I6NE87
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4787
gene id: 931890:Ecym_4787
uniprot id: G8JSS6
names: Similarity
messages: Belongs to the MEMO1 family.

931890:Ecym 6025
gene id: 931890:Ecym_6025
uniprot id: G8JUV1
names: Similarity
messages: Belongs to the universal ribosomal protein uL4 family.

931890:Ecym 8176
gene id: 931890:Ecym_8176
uniprot id: G8JX88
names: Similarity
messages: Belongs to the asparaginase 1 family.

931890:Ecym 7002
gene id: 931890:Ecym_7002
uniprot id: G8JVJ6
names: Similarity
messages: Belongs to the PdxS/SNZ family.

931890:Ecym 5571
gene id: 931890:Ecym_5571
uniprot id: I6NE17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2H phosphoesterase superfamily. CPD1 family.
messages: Golgi apparatus
messages: Involved in the metabolism of ADP-ribose 1',2'-cyclic phosphate which is produced as a consequence of tRNA splicing.

931890:Ecym 5413
gene id: 931890:Ecym_5413
uniprot id: I6NDM5
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.

931890:Ecym 6311
gene id: 931890:Ecym_6311
uniprot id: G8JUB0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetyltransferase family.
messages: Mitochondrion
messages: N-acetylglutamate synthase involved in arginine biosynthesis.

931890:Ecym 6044
gene id: 931890:Ecym_6044
uniprot id: G8JUW8
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 3515
gene id: 931890:Ecym_3515
uniprot id: G8JS74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad17/RAD24 family.
messages: Nucleus

931890:Ecym 5290
gene id: 931890:Ecym_5290
uniprot id: I6NDB0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad21 family.
messages: Nucleus

931890:Ecym 5216
gene id: 931890:Ecym_5216
uniprot id: I6ND43
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP46 family.
messages: Mitochondrion
messages: Putative mitochondrial redox protein which could be involved in the reduction of small toxic molecules.

931890:Ecym 3328
gene id: 931890:Ecym_3328
uniprot id: G8JRP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. METTL21 family. EFM6 subfamily.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that methylates elongation factor 1-alpha.

931890:Ecym 5666
gene id: 931890:Ecym_5666
uniprot id: I6NEA7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 4313
gene id: 931890:Ecym_4313
uniprot id: G8JTM3
names: Similarity
messages: Belongs to the FGGY kinase family.

931890:Ecym 3611
gene id: 931890:Ecym_3611
uniprot id: G8JQT8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class VI-like SAM-binding methyltransferase superfamily. PEMT/PEM2 methyltransferase family.
messages: Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC).
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion membrane

931890:Ecym 7330
gene id: 931890:Ecym_7330
uniprot id: G8JWE8
names: Similarity
messages: Belongs to the PrpD family.

931890:Ecym 2102
gene id: 931890:Ecym_2102
uniprot id: G8JPK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. BUD23/WBSCR22 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 8185
gene id: 931890:Ecym_8185
uniprot id: G8JX97
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 7103
gene id: 931890:Ecym_7103
uniprot id: G8JVU0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the radical SAM superfamily. Lipoyl synthase family.
messages: Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
messages: Mitochondrion

931890:Ecym 8125
gene id: 931890:Ecym_8125
uniprot id: G8JX42
names: Subcellular Location Annotation
messages: Mitochondrion

931890:Ecym 1059
gene id: 931890:Ecym_1059
uniprot id: G8JMA8
names: Similarity
messages: Belongs to the multicopper oxidase family.

931890:Ecym 4629
gene id: 931890:Ecym_4629
uniprot id: G8JSD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 6338
gene id: 931890:Ecym_6338
uniprot id: G8JUD4
names: Similarity
messages: Belongs to the aspartate/ornithine carbamoyltransferase superfamily.

931890:Ecym 3036
gene id: 931890:Ecym_3036
uniprot id: G8JQY1
names: Function
names: Similarity
messages: Belongs to the type IB topoisomerase family.
messages: Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus removing DNA supercoils. Finally, in the religation step, the DNA 5'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.

931890:Ecym 5625
gene id: 931890:Ecym_5625
uniprot id: I6NE69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-B family.
messages: Nucleus

931890:Ecym 6171
gene id: 931890:Ecym_6171
uniprot id: G8JV77
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 6332
gene id: 931890:Ecym_6332
uniprot id: G8JUC8
names: Similarity
messages: Belongs to the IML2 family.

931890:Ecym 4386
gene id: 931890:Ecym_4386
uniprot id: G8JTT8
names: Similarity
messages: Belongs to the UQCRH/QCR6 family.

931890:Ecym 3053
gene id: 931890:Ecym_3053
uniprot id: G8JQZ6
names: Similarity
messages: Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.

931890:Ecym 2514
gene id: 931890:Ecym_2514
uniprot id: G8JPX7
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 4301
gene id: 931890:Ecym_4301
uniprot id: G8JTL1
names: Similarity
messages: Belongs to the eIF2D family.

931890:Ecym 2298
gene id: 931890:Ecym_2298
uniprot id: G8JQ38
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

931890:Ecym 4266
gene id: 931890:Ecym_4266
uniprot id: G8JTH7
names: Activity Regulation
names: Similarity
names: Subcellular Location Annotation
messages: Activated by threonine and tyrosine phosphorylation.
messages: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
messages: Nucleus

931890:Ecym 3505
gene id: 931890:Ecym_3505
uniprot id: G8JS64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin family.
messages: cytoskeleton

931890:Ecym 5391
gene id: 931890:Ecym_5391
uniprot id: I6NDK4
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 2-oxoacid dehydrogenase family.
messages: Binds 1 lipoyl cofactor covalently.
messages: Mitochondrion
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

931890:Ecym 1074
gene id: 931890:Ecym_1074
uniprot id: G8JMC3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 28 family.
messages: Membrane

931890:Ecym 4474
gene id: 931890:Ecym_4474
uniprot id: G8JU11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMA20 family.
messages: Cytoplasm
messages: Involved in translation.

931890:Ecym 2690
gene id: 931890:Ecym_2690
uniprot id: G8JPD2
names: Function
names: Similarity
messages: Belongs to the eIF-1A family.
messages: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.

931890:Ecym 3433
gene id: 931890:Ecym_3433
uniprot id: G8JS00
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GTP-binding SRP family. SRP54 subfamily.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). Binds to the signal sequence of presecretory proteins when they emerge from the ribosomes.
messages: Cytoplasm
messages: Has a two domain structure: the G-domain binds GTP; the M-domain binds the 7S RNA in presence of SRP19 and also binds the signal sequence.
messages: Signal recognition particle consists of a 7S RNA molecule and at least six protein subunits.

931890:Ecym 1331
gene id: 931890:Ecym_1331
uniprot id: G8JNA2
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair.
messages: Belongs to the XPG/RAD2 endonuclease family. EXO1 subfamily.
messages: Binds 2 magnesium ions per subunit. They probably participate in the reaction catalyzed by the enzyme. May bind an additional third magnesium ion after substrate binding.
messages: Nucleus

931890:Ecym 3417
gene id: 931890:Ecym_3417
uniprot id: G8JRY4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KAR5 family.
messages: Endoplasmic reticulum membrane
messages: Nucleus membrane
messages: Required for nuclear membrane fusion during karyogamy.

931890:Ecym 3338
gene id: 931890:Ecym_3338
uniprot id: G8JRQ9
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H3 family.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 2558
gene id: 931890:Ecym_2558
uniprot id: G8JQB9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

931890:Ecym 2797
gene id: 931890:Ecym_2797
uniprot id: G8JQD2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 4389
gene id: 931890:Ecym_4389
uniprot id: G8JTU0
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

931890:Ecym 8174
gene id: 931890:Ecym_8174
uniprot id: G8JX86
names: Function
names: Similarity
messages: Belongs to the AB hydrolase superfamily.
messages: Demethylates proteins that have been reversibly carboxymethylated.

931890:Ecym 3275
gene id: 931890:Ecym_3275
uniprot id: G8JRJ9
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 5021
gene id: 931890:Ecym_5021
uniprot id: I6NCN0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit B family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.

931890:Ecym 4466
gene id: 931890:Ecym_4466
uniprot id: G8JU03
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PAN1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane
messages: actin patch

931890:Ecym 2651
gene id: 931890:Ecym_2651
uniprot id: G8JNT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ORC2 family.
messages: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
messages: Component of the origin recognition complex (ORC).
messages: Nucleus

931890:Ecym 2457
gene id: 931890:Ecym_2457
uniprot id: G8JPC6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

931890:Ecym 2702
gene id: 931890:Ecym_2702
uniprot id: G8JPE2
names: Similarity
messages: Belongs to the sorting nexin family.

931890:Ecym 4056
gene id: 931890:Ecym_4056
uniprot id: G8JSY4
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 4666
gene id: 931890:Ecym_4666
uniprot id: G8JSG5
names: Similarity
messages: Belongs to the TMEM14 family.

931890:Ecym 3354
gene id: 931890:Ecym_3354
uniprot id: G8JRS3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 5 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 2346
gene id: 931890:Ecym_2346
uniprot id: G8JQ79
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the histone deacetylase family. HD Type 1 subfamily.
messages: Nucleus

931890:Ecym 3353
gene id: 931890:Ecym_3353
uniprot id: G8JRS2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-14 family.
messages: Component of the peroxisomal translocation machinery.
messages: Peroxisome membrane

931890:Ecym 2046
gene id: 931890:Ecym_2046
uniprot id: G8JP03
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

931890:Ecym 4063
gene id: 931890:Ecym_4063
uniprot id: G8JSZ0
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.
messages: Catalyzes the methyl transfer from S-adenosyl-methionine to the C-24 of zymosterol to form fecosterol.

931890:Ecym 7050
gene id: 931890:Ecym_7050
uniprot id: G8JVP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GDT1 family.
messages: Membrane

931890:Ecym 7379
gene id: 931890:Ecym_7379
uniprot id: G8JWJ0
names: Similarity
messages: Belongs to the C/M/P thioester hydrolase family.

931890:Ecym 7453
gene id: 931890:Ecym_7453
uniprot id: G8JWQ7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

931890:Ecym 2747
gene id: 931890:Ecym_2747
uniprot id: G8JPY3
names: Similarity
messages: Belongs to the SH3YL1 family.

931890:Ecym 4716
gene id: 931890:Ecym_4716
uniprot id: G8JSL4
names: Function
names: Similarity
names: Subunit
messages: Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins.
messages: Belongs to the NMT family.
messages: Monomer.

931890:Ecym 8046
gene id: 931890:Ecym_8046
uniprot id: G8JWW8
names: Similarity
messages: Belongs to the cullin family.

931890:Ecym 8120
gene id: 931890:Ecym_8120
uniprot id: G8JX37
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

931890:Ecym 2297
gene id: 931890:Ecym_2297
uniprot id: G8JQ37
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transcriptional coactivator PC4 family.
messages: Nucleus

931890:Ecym 2151
gene id: 931890:Ecym_2151
uniprot id: G8JNI7
names: Similarity
messages: Belongs to the eIF-2-beta/eIF-5 family.

931890:Ecym 2071
gene id: 931890:Ecym_2071
uniprot id: G8JPH9
names: Similarity
messages: Belongs to the universal ribosomal protein uS4 family.

931890:Ecym 4531
gene id: 931890:Ecym_4531
uniprot id: G8JU65
names: Similarity
messages: Belongs to the VPS29 family.

931890:Ecym 1412
gene id: 931890:Ecym_1412
uniprot id: G8JM69
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat NOL10/ENP2 family.
messages: nucleolus

931890:Ecym 3172
gene id: 931890:Ecym_3172
uniprot id: G8JRA4
names: Similarity
messages: Belongs to the glutaredoxin family.

931890:Ecym 1072
gene id: 931890:Ecym_1072
uniprot id: G8JMC1
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5634
gene id: 931890:Ecym_5634
uniprot id: I6NE78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NSE4 family.
messages: Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
messages: Component of the SMC5-SMC6 complex.
messages: Nucleus

931890:Ecym 7366
gene id: 931890:Ecym_7366
uniprot id: G8JWH7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELOF1 family.
messages: Nucleus
messages: Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions.

931890:Ecym 7335
gene id: 931890:Ecym_7335
uniprot id: G8JWF2
names: Similarity
messages: Belongs to the peptidase M24B family.

931890:Ecym 3180
gene id: 931890:Ecym_3180
uniprot id: G8JRB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fatty acid desaturase type 1 family.
messages: Membrane

931890:Ecym 1519
gene id: 931890:Ecym_1519
uniprot id: G8JMS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TMEM208 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2216
gene id: 931890:Ecym_2216
uniprot id: G8JP60
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KXD1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
messages: Endosome

931890:Ecym 7251
gene id: 931890:Ecym_7251
uniprot id: G8JW80
names: Similarity
messages: Belongs to the cytochrome b5 family.

931890:Ecym 1532
gene id: 931890:Ecym_1532
uniprot id: G8JMT7
names: Similarity
messages: Belongs to the universal ribosomal protein uL16 family.

931890:Ecym 3560
gene id: 931890:Ecym_3560
uniprot id: G8JQP7
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

931890:Ecym 5344
gene id: 931890:Ecym_5344
uniprot id: I6NDG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC6 subfamily.
messages: Chromosome
messages: Nucleus

931890:Ecym 6226
gene id: 931890:Ecym_6226
uniprot id: G8JVC9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GHMP kinase family. Mevalonate kinase subfamily.
messages: Cytoplasm
messages: Mevalonate kinase; part of the second module of ergosterol biosynthesis pathway that includes the middle steps of the pathway. The second module is carried out in the vacuole and involves the formation of farnesyl diphosphate, which is also an important intermediate in the biosynthesis of ubiquinone, dolichol, heme and prenylated proteins.

931890:Ecym 7171
gene id: 931890:Ecym_7171
uniprot id: G8JW04
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7175
gene id: 931890:Ecym_7175
uniprot id: G8JW08
names: Similarity
messages: Belongs to the PPP4R2 family.

931890:Ecym 7183
gene id: 931890:Ecym_7183
uniprot id: G8JW16
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6289
gene id: 931890:Ecym_6289
uniprot id: G8JVJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL54 family.
messages: Mitochondrion

931890:Ecym 6342
gene id: 931890:Ecym_6342
uniprot id: G8JUD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGW family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

931890:Ecym 3084
gene id: 931890:Ecym_3084
uniprot id: G8JR27
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cornichon family.
messages: Membrane

931890:Ecym 3183
gene id: 931890:Ecym_3183
uniprot id: G8JRB3
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931890:Ecym 8322
gene id: 931890:Ecym_8322
uniprot id: G8JXM6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the activator 1 large subunit family.
messages: Nucleus

931890:Ecym 1183
gene id: 931890:Ecym_1183
uniprot id: G8JMW9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family.
messages: Membrane

931890:Ecym 3532
gene id: 931890:Ecym_3532
uniprot id: G8JQM5
names: Similarity
messages: Belongs to the pseudouridine synthase TruB family.

931890:Ecym 4506
gene id: 931890:Ecym_4506
uniprot id: G8JU40
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5416
gene id: 931890:Ecym_5416
uniprot id: I6NDM8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the YAF9 family.
messages: Component of the SWR1 chromatin-remodeling complex and of the NuA4 histone acetyltransferase complex.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for an H2A variant leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised.
messages: Cytoplasm
messages: Nucleus
messages: The coiled-coil domain is required for assembly into the NuA4 complex.

931890:Ecym 3115
gene id: 931890:Ecym_3115
uniprot id: G8JR53
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

931890:Ecym 3447
gene id: 931890:Ecym_3447
uniprot id: G8JS13
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

931890:Ecym 8386
gene id: 931890:Ecym_8386
uniprot id: G8JXT2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 7122
gene id: 931890:Ecym_7122
uniprot id: G8JVV7
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 2179
gene id: 931890:Ecym_2179
uniprot id: G8JNL3
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

931890:Ecym 5551
gene id: 931890:Ecym_5551
uniprot id: I6NDZ9
names: Similarity
messages: In the C-terminal section; belongs to the trehalose phosphatase family.
messages: In the N-terminal section; belongs to the glycosyltransferase 20 family.

931890:Ecym 4333
gene id: 931890:Ecym_4333
uniprot id: G8JTP2
names: Similarity
messages: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.

931890:Ecym 5139
gene id: 931890:Ecym_5139
uniprot id: I6NCX4
names: Similarity
messages: Belongs to the universal ribosomal protein uS17 family.

931890:Ecym 5112
gene id: 931890:Ecym_5112
uniprot id: I6NCV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the XPG/RAD2 endonuclease family. XPG subfamily.
messages: Nucleus

931890:Ecym 8257
gene id: 931890:Ecym_8257
uniprot id: G8JXG5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS53 family.
messages: Endosome membrane
messages: Membrane
messages: trans-Golgi network membrane

931890:Ecym 7124
gene id: 931890:Ecym_7124
uniprot id: G8JVV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CND2 (condensin subunit 2) family.
messages: Chromosome
messages: Cytoplasm
messages: Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.

931890:Ecym 5189
gene id: 931890:Ecym_5189
uniprot id: I6ND19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFH5 family.
messages: Cytoplasm
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Microsome membrane
messages: Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane. Heme-binding protein that may play a role in organic oxidant-induced stress responses.

931890:Ecym 1070
gene id: 931890:Ecym_1070
uniprot id: G8JMB9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PRM1 family.
messages: Cell membrane
messages: Involved in cell fusion during mating by stabilizing the plasma membrane fusion event.
messages: Membrane

931890:Ecym 1286
gene id: 931890:Ecym_1286
uniprot id: G8JN61
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RER1 family.
messages: Involved in the retrieval of endoplasmic reticulum membrane proteins from the early Golgi compartment.
messages: Membrane

931890:Ecym 7435
gene id: 931890:Ecym_7435
uniprot id: G8JWP1
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

931890:Ecym 7441
gene id: 931890:Ecym_7441
uniprot id: G8JWP6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Catalyzes the exchange of ADP and ATP across the membrane.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Monomer.

931890:Ecym 7393
gene id: 931890:Ecym_7393
uniprot id: G8JWK4
names: Similarity
messages: Belongs to the peptidase M18 family.

931890:Ecym 2616
gene id: 931890:Ecym_2616
uniprot id: G8JQJ6
names: Similarity
messages: Belongs to the COG4 family.

931890:Ecym 4459
gene id: 931890:Ecym_4459
uniprot id: G8JTZ8
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

931890:Ecym 6164
gene id: 931890:Ecym_6164
uniprot id: G8JV70
names: Function
names: Similarity
messages: Belongs to the tRNA-intron endonuclease family.
messages: Constitutes one of the two catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA body.

931890:Ecym 8368
gene id: 931890:Ecym_8368
uniprot id: G8JXR5
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Mitochondrion

931890:Ecym 7067
gene id: 931890:Ecym_7067
uniprot id: G8JVQ5
names: Similarity
messages: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.

931890:Ecym 2053
gene id: 931890:Ecym_2053
uniprot id: G8JP10
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL18 family.

931890:Ecym 3232
gene id: 931890:Ecym_3232
uniprot id: G8JRF7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7076
gene id: 931890:Ecym_7076
uniprot id: G8JVR4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Alcohol acetyltransferase that catalyzes the synthesis of ethyl acetate from ethanol and acetyl-CoA (PubMed:28356220). Can also function as a thioesterase by hydrolyzing acetyl-CoA in the absence of ethanol, as well as esterase hydrolyzing ethyl acetate (By similarity).
messages: Belongs to the AB hydrolase superfamily.
messages: Mitochondrion

931890:Ecym 7265
gene id: 931890:Ecym_7265
uniprot id: G8JW94
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus

931890:Ecym 5250
gene id: 931890:Ecym_5250
uniprot id: I6ND74
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

931890:Ecym 3150
gene id: 931890:Ecym_3150
uniprot id: G8JR84
names: Similarity
messages: Belongs to the activator 1 small subunits family.

931890:Ecym 4145
gene id: 931890:Ecym_4145
uniprot id: G8JT70
names: Similarity
messages: Belongs to the TCP-1 chaperonin family.

931890:Ecym 5403
gene id: 931890:Ecym_5403
uniprot id: I6NDL6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4473
gene id: 931890:Ecym_4473
uniprot id: G8JU10
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork.
messages: Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily.
messages: Interacts with the MHF histone-fold complex to form the FANCM-MHF complex.
messages: Nucleus

931890:Ecym 1254
gene id: 931890:Ecym_1254
uniprot id: G8JN32
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAM1 family.
messages: Nucleus
messages: kinetochore

931890:Ecym 3576
gene id: 931890:Ecym_3576
uniprot id: G8JQR2
names: Similarity
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.

931890:Ecym 6346
gene id: 931890:Ecym_6346
uniprot id: G8JUE2
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the very long-chain fatty acids dehydratase HACD family.
messages: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 8246
gene id: 931890:Ecym_8246
uniprot id: G8JXF6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

931890:Ecym 7403
gene id: 931890:Ecym_7403
uniprot id: G8JWL4
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 2535
gene id: 931890:Ecym_2535
uniprot id: G8JQ97
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NAC-beta family.
messages: Cytoplasm
messages: Nucleus
messages: Part of the nascent polypeptide-associated complex (NAC).

931890:Ecym 6361
gene id: 931890:Ecym_6361
uniprot id: G8JUF7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HEATR1/UTP10 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

931890:Ecym 6021
gene id: 931890:Ecym_6021
uniprot id: G8JUU8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 5059
gene id: 931890:Ecym_5059
uniprot id: I6NCQ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the SNW family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

931890:Ecym 6179
gene id: 931890:Ecym_6179
uniprot id: G8JV83
names: Similarity
messages: Belongs to the VPS8 family.

931890:Ecym 3283
gene id: 931890:Ecym_3283
uniprot id: G8JRK7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRM6/GCD10 family.
messages: Heterotetramer.
messages: Nucleus
messages: Substrate-binding subunit of tRNA (adenine-N1-)-methyltransferase, which catalyzes the formation of N1-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.

931890:Ecym 4328
gene id: 931890:Ecym_4328
uniprot id: G8JTN7
names: Cofactor
names: Similarity
messages: Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family.
messages: Can also use Mn(2+) ion.

931890:Ecym 6181
gene id: 931890:Ecym_6181
uniprot id: G8JV85
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF5 family.
messages: Nucleus
messages: Part of the chromatin structure-remodeling complex (RSC) which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is essential for mitotic growth and required for cell cycle progression.

931890:Ecym 4282
gene id: 931890:Ecym_4282
uniprot id: G8JTJ2
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 3523
gene id: 931890:Ecym_3523
uniprot id: G8JQL7
names: Similarity
messages: Belongs to the DNA polymerase type-B-like family.

931890:Ecym 2468
gene id: 931890:Ecym_2468
uniprot id: G8JPT6
names: Similarity
messages: Belongs to the UPP synthase family.

931890:Ecym 7041
gene id: 931890:Ecym_7041
uniprot id: G8JVN2
names: Function
names: Similarity
messages: Belongs to the GPI family.
messages: In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis.

931890:Ecym 4725
gene id: 931890:Ecym_4725
uniprot id: G8JSM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the adenylate kinase family. AK6 subfamily.
messages: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 2511
gene id: 931890:Ecym_2511
uniprot id: G8JPX4
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

931890:Ecym 4737
gene id: 931890:Ecym_4737
uniprot id: G8JSN2
names: Similarity
messages: Belongs to the small heat shock protein (HSP20) family.

931890:Ecym 1159
gene id: 931890:Ecym_1159
uniprot id: G8JMQ5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the helicase family. PIF1 subfamily.
messages: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Involved in the maintenance of ribosomal (rDNA). Required for efficient fork arrest at the replicaion fork barrier within rDNA. Involved in the maintenance of mitochondrial (mtDNA). Required to maintain mtDNA under conditions that introduce dsDNA breaks in mtDNA, either preventing or repairing dsDNA breaks. May inhibit replication progression to allow time for repair. May have a general role in chromosomal replication by affecting Okazaki fragment maturation. May have a role in conjunction with DNA2 helicase/nuclease in 5'-flap extension during Okazaki fragment processing.
messages: Mitochondrion
messages: Monomer. Interacts with telomerase.
messages: Nucleus

931890:Ecym 1503
gene id: 931890:Ecym_1503
uniprot id: G8JMR2
names: Similarity
messages: Belongs to the glycosyl hydrolase 47 family.

931890:Ecym 2786
gene id: 931890:Ecym_2786
uniprot id: G8JQ21
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 5599
gene id: 931890:Ecym_5599
uniprot id: I6NE44
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit I family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

931890:Ecym 5402
gene id: 931890:Ecym_5402
uniprot id: I6NDL5
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

931890:Ecym 3528
gene id: 931890:Ecym_3528
uniprot id: G8JQM2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2496
gene id: 931890:Ecym_2496
uniprot id: G8JPW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation.
messages: Belongs to the glycosyltransferase 22 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7467
gene id: 931890:Ecym_7467
uniprot id: G8JWS1
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

931890:Ecym 4030
gene id: 931890:Ecym_4030
uniprot id: G8JSV9
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PLPL family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Lipid hydrolase.
messages: Membrane

931890:Ecym 2478
gene id: 931890:Ecym_2478
uniprot id: G8JPU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CLASP family.
messages: Belongs to the TOG/XMAP215 family.
messages: spindle

931890:Ecym 3133
gene id: 931890:Ecym_3133
uniprot id: G8JR68
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS28 family.

931890:Ecym 7084
gene id: 931890:Ecym_7084
uniprot id: G8JVS1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
messages: Membrane

931890:Ecym 8200
gene id: 931890:Ecym_8200
uniprot id: G8JXB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC6 family.
messages: Nucleus

931890:Ecym 3588
gene id: 931890:Ecym_3588
uniprot id: G8JQS1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7448
gene id: 931890:Ecym_7448
uniprot id: G8JWQ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.
messages: Belongs to the DNA polymerase alpha subunit B family.
messages: Nucleus

931890:Ecym 4512
gene id: 931890:Ecym_4512
uniprot id: G8JU46
names: Similarity
messages: Belongs to the glycosyl hydrolase 18 family.

931890:Ecym 2204
gene id: 931890:Ecym_2204
uniprot id: G8JP48
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL12 family.

931890:Ecym 3052
gene id: 931890:Ecym_3052
uniprot id: G8JQZ5
names: Similarity
messages: Belongs to the protein kinase superfamily. ADCK protein kinase family.

931890:Ecym 8291
gene id: 931890:Ecym_8291
uniprot id: G8JXJ6
names: Similarity
messages: Belongs to the peptidase C14B family.

931890:Ecym 8104
gene id: 931890:Ecym_8104
uniprot id: G8JX24
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.

931890:Ecym 7461
gene id: 931890:Ecym_7461
uniprot id: G8JWR5
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family.

931890:Ecym 6042
gene id: 931890:Ecym_6042
uniprot id: G8JUW7
names: Similarity
messages: Belongs to the thiolase-like superfamily. Thiolase family.

931890:Ecym 7059
gene id: 931890:Ecym_7059
uniprot id: G8JVP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the alkaline ceramidase family.
messages: Membrane

931890:Ecym 2791
gene id: 931890:Ecym_2791
uniprot id: G8JQ26
names: Similarity
messages: Belongs to the VPS52 family.

931890:Ecym 4249
gene id: 931890:Ecym_4249
uniprot id: G8JTG1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat peroxin-7 family.
messages: Cytoplasm

931890:Ecym 5103
gene id: 931890:Ecym_5103
uniprot id: I6NCU4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.
messages: Membrane

931890:Ecym 5370
gene id: 931890:Ecym_5370
uniprot id: I6NDI4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OST3/OST6 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5277
gene id: 931890:Ecym_5277
uniprot id: I6ND98
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the mitochondrion-specific ribosomal protein mS37 family.
messages: Component of the mitochondrial small ribosomal subunit.
messages: Involved in mitochondrial genome encoded proteins translation.
messages: Mitochondrion

931890:Ecym 8220
gene id: 931890:Ecym_8220
uniprot id: G8JXD1
names: Function
names: Similarity
messages: Belongs to the pseudouridine synthase RluA family.
messages: Responsible for synthesis of pseudouridine from uracil.

931890:Ecym 7217
gene id: 931890:Ecym_7217
uniprot id: G8JW48
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4298
gene id: 931890:Ecym_4298
uniprot id: G8JTK8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1446
gene id: 931890:Ecym_1446
uniprot id: G8JMF5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF beta subunit family.
messages: Nucleus

931890:Ecym 8297
gene id: 931890:Ecym_8297
uniprot id: G8JXK2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1405
gene id: 931890:Ecym_1405
uniprot id: G8JM63
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4034
gene id: 931890:Ecym_4034
uniprot id: G8JSW3
names: Function
names: Similarity
messages: Belongs to the TVP38/TMEM64 family.
messages: Golgi membrane protein involved in vesicular trafficking and spindle migration.

931890:Ecym 1341
gene id: 931890:Ecym_1341
uniprot id: G8JNB1
names: Similarity
names: Subunit
messages: Belongs to the phosphoglycerate kinase family.
messages: Monomer.

931890:Ecym 5307
gene id: 931890:Ecym_5307
uniprot id: I6NDC6
names: Similarity
messages: Belongs to the TCP11 family.

931890:Ecym 1073
gene id: 931890:Ecym_1073
uniprot id: G8JMC2
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

931890:Ecym 8139
gene id: 931890:Ecym_8139
uniprot id: G8JX56
names: Activity Regulation
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.
messages: Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.
messages: Belongs to the carbohydrate kinase pfkB family.
messages: Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
messages: Cytoplasm
messages: Homodimer.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus
messages: Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.

931890:Ecym 6184
gene id: 931890:Ecym_6184
uniprot id: G8JV88
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 2796
gene id: 931890:Ecym_2796
uniprot id: G8JQ31
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutS family.
messages: Component of the post-replicative DNA mismatch repair system (MMR).
messages: Nucleus

931890:Ecym 4628
gene id: 931890:Ecym_4628
uniprot id: G8JSD1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

931890:Ecym 3421
gene id: 931890:Ecym_3421
uniprot id: G8JRY8
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ArgJ family.
messages: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.
messages: Heterodimer of an alpha and a beta chain.
messages: Mitochondrion matrix
messages: The alpha and beta chains are autoproteolytically processed from a single precursor protein within the mitochondrion.

931890:Ecym 3355
gene id: 931890:Ecym_3355
uniprot id: G8JRS4
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair.
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Component of the INO80 chromatin-remodeling complex.
messages: Nucleus
messages: The DBINO region is involved in binding to DNA.

931890:Ecym 7259
gene id: 931890:Ecym_7259
uniprot id: G8JW88
names: Cofactor
names: Similarity
messages: Belongs to the malic enzymes family.
messages: Divalent metal cations. Prefers magnesium or manganese.

931890:Ecym 3577
gene id: 931890:Ecym_3577
uniprot id: G8JQR3
names: Similarity
messages: Belongs to the Cdt1 family.

931890:Ecym 4392
gene id: 931890:Ecym_4392
uniprot id: G8JTU3
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 1264
gene id: 931890:Ecym_1264
uniprot id: G8JN42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase T1B family.
messages: Component of the proteasome complex.
messages: Component of the proteasome, a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
messages: Cytoplasm
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

931890:Ecym 4102
gene id: 931890:Ecym_4102
uniprot id: G8JT28
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

931890:Ecym 1319
gene id: 931890:Ecym_1319
uniprot id: G8JN90
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 1289
gene id: 931890:Ecym_1289
uniprot id: G8JN64
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase e1/e2 subunit family.
messages: Membrane

931890:Ecym 6310
gene id: 931890:Ecym_6310
uniprot id: G8JUA9
names: Function
names: Similarity
messages: Belongs to the SHMT family.
messages: Interconversion of serine and glycine.

931890:Ecym 5155
gene id: 931890:Ecym_5155
uniprot id: I6NCY9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the small Tim family.
messages: Heterohexamer.
messages: Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space.
messages: Mitochondrion inner membrane
messages: The twin CX3C motif contains 4 conserved Cys residues that form 2 disulfide bonds in the mitochondrial intermembrane space.

931890:Ecym 2421
gene id: 931890:Ecym_2421
uniprot id: G8JP95
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

931890:Ecym 4423
gene id: 931890:Ecym_4423
uniprot id: G8JTW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 18 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 4091
gene id: 931890:Ecym_4091
uniprot id: G8JT17
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. DOT1 family.
messages: Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone.
messages: Nucleus

931890:Ecym 3254
gene id: 931890:Ecym_3254
uniprot id: G8JRH8
names: Function
names: Similarity
messages: Belongs to the dus family. Dus3 subfamily.
messages: Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs.

931890:Ecym 8068
gene id: 931890:Ecym_8068
uniprot id: G8JWZ0
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm
messages: Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.

931890:Ecym 4550
gene id: 931890:Ecym_4550
uniprot id: G8JU82
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPP2 family.
messages: Nucleus

931890:Ecym 3123
gene id: 931890:Ecym_3123
uniprot id: G8JR58
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4213
gene id: 931890:Ecym_4213
uniprot id: G8JTC7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC37 family.
messages: Cytoplasm

931890:Ecym 8422
gene id: 931890:Ecym_8422
uniprot id: G8JXW7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family.
messages: Nucleus matrix

931890:Ecym 7051
gene id: 931890:Ecym_7051
uniprot id: G8JVP2
names: Similarity
messages: Belongs to the AAA ATPase family. PCH2 subfamily.

931890:Ecym 7044
gene id: 931890:Ecym_7044
uniprot id: G8JVN5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 8 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 2172
gene id: 931890:Ecym_2172
uniprot id: G8JNK7
names: Similarity
messages: Belongs to the SELO family.

931890:Ecym 2398
gene id: 931890:Ecym_2398
uniprot id: G8JNR3
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the diacylglycerol acyltransferase family.
messages: Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates.
messages: Endoplasmic reticulum membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931890:Ecym 8103
gene id: 931890:Ecym_8103
uniprot id: G8JX23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EBP2 family.
messages: nucleolus

931890:Ecym 6208
gene id: 931890:Ecym_6208
uniprot id: G8JVB2
names: Similarity
messages: Belongs to the heat shock protein 70 family.

931890:Ecym 4041
gene id: 931890:Ecym_4041
uniprot id: G8JSW9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1432
gene id: 931890:Ecym_1432
uniprot id: G8JM88
names: Similarity
messages: Belongs to the Fmt family.

931890:Ecym 2276
gene id: 931890:Ecym_2276
uniprot id: G8JPR7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF6 family.
messages: Nucleus

931890:Ecym 5013
gene id: 931890:Ecym_5013
uniprot id: I6NCM4
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

931890:Ecym 8205
gene id: 931890:Ecym_8205
uniprot id: G8JXB6
names: Subcellular Location Annotation
messages: Mitochondrion intermembrane space

931890:Ecym 2313
gene id: 931890:Ecym_2313
uniprot id: G8JQ53
names: Similarity
names: Subunit
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.
messages: Octamer of two non-identical subunits IDH1 and IDH2.

931890:Ecym 2217
gene id: 931890:Ecym_2217
uniprot id: G8JP61
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Adaptor protein complex 3 (AP-3) is a heterotetramer.
messages: Belongs to the adaptor complexes large subunit family.
messages: Golgi apparatus
messages: Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane.

931890:Ecym 4649
gene id: 931890:Ecym_4649
uniprot id: G8JSF0
names: Function
names: Similarity
messages: Belongs to the WD repeat DDB2/WDR76 family.
messages: DNA-binding protein that binds to both single- and double-stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.

931890:Ecym 4046
gene id: 931890:Ecym_4046
uniprot id: G8JSX4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPF2 family.
messages: nucleolus

931890:Ecym 7249
gene id: 931890:Ecym_7249
uniprot id: G8JW78
names: Similarity
messages: Belongs to the PDCD5 family.

931890:Ecym 3551
gene id: 931890:Ecym_3551
uniprot id: G8JQP0
names: Function
names: Similarity
messages: Belongs to the MnmA/TRMU family.
messages: Catalyzes the 2-thiolation of uridine at the wobble position (U34) of mitochondrial tRNA(Lys), tRNA(Glu) and tRNA(Gln). Required for the formation of 5-taurinomethyl-2-thiouridine (tm5s2U) of mitochondrial tRNA(Lys), tRNA(Glu), and tRNA(Gln) at the wobble position. ATP is required to activate the C2 atom of the wobble base.

931890:Ecym 7368
gene id: 931890:Ecym_7368
uniprot id: G8JWH9
names: Similarity
messages: Belongs to the RCAN family.

931890:Ecym 8163
gene id: 931890:Ecym_8163
uniprot id: G8JX76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YSP2 family.
messages: Membrane

931890:Ecym 1149
gene id: 931890:Ecym_1149
uniprot id: G8JMP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SSRP1 family.
messages: Chromosome
messages: Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II.
messages: Nucleus

931890:Ecym 7056
gene id: 931890:Ecym_7056
uniprot id: G8JVP4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SEC16 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
messages: Membrane

931890:Ecym 4658
gene id: 931890:Ecym_4658
uniprot id: G8JSF8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EAF6 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Component of the NuA4 histone acetyltransferase complex.
messages: Nucleus

931890:Ecym 5322
gene id: 931890:Ecym_5322
uniprot id: I6NDD9
names: Similarity
messages: Belongs to the SIN1 family.

931890:Ecym 6330
gene id: 931890:Ecym_6330
uniprot id: G8JUC6
names: Similarity
messages: Belongs to the actin family.

931890:Ecym 5436
gene id: 931890:Ecym_5436
uniprot id: I6NDP6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the V-ATPase 116 kDa subunit family.
messages: Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.
messages: Membrane

931890:Ecym 5521
gene id: 931890:Ecym_5521
uniprot id: I6NDX0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Binds 1 zinc ion per subunit.
messages: Cytoplasm
messages: In the N-terminal section; belongs to the HesA/MoeB/ThiF family. UBA4 subfamily.
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

931890:Ecym 1474
gene id: 931890:Ecym_1474
uniprot id: G8JMI3
names: Similarity
messages: Belongs to the glycosyl hydrolase 76 family.

931890:Ecym 7273
gene id: 931890:Ecym_7273
uniprot id: G8JWA0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ETF alpha-subunit/FixB family.
messages: Binds 1 FAD per dimer.
messages: Heterodimer of an alpha and a beta subunit.
messages: Mitochondrion matrix
messages: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).

931890:Ecym 1497
gene id: 931890:Ecym_1497
uniprot id: G8JMQ6
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.

931890:Ecym 7338
gene id: 931890:Ecym_7338
uniprot id: G8JWF3
names: Similarity
messages: Belongs to the PITHD1 family.

931890:Ecym 1218
gene id: 931890:Ecym_1218
uniprot id: G8JN01
names: Function
names: Similarity
messages: Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
messages: Belongs to the glycogen phosphorylase family.

931890:Ecym 7014
gene id: 931890:Ecym_7014
uniprot id: G8JVK6
names: Similarity
messages: Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class II DHOase subfamily.

931890:Ecym 7057
gene id: 931890:Ecym_7057
uniprot id: G8JVP5
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the ELP3 family.
messages: Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
messages: Catalytic tRNA acetyltransferase subunit of the elongator complex, which is required for multiple tRNA modifications, including mcm5U (5-methoxycarbonylmethyl uridine), mcm5s2U (5-methoxycarbonylmethyl-2-thiouridine), and ncm5U (5-carbamoylmethyl uridine). In the elongator complex, acts as a tRNA uridine(34) acetyltransferase by mediating formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.

931890:Ecym 4562
gene id: 931890:Ecym_4562
uniprot id: G8JU92
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCTP family.
messages: Involved in protein synthesis. Involved in microtubule stabilization.
messages: cytoskeleton

931890:Ecym 8042
gene id: 931890:Ecym_8042
uniprot id: G8JWW4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein P1/P2 family.

931890:Ecym 1301
gene id: 931890:Ecym_1301
uniprot id: G8JN75
names: Similarity
messages: Belongs to the UPF0357 family.

931890:Ecym 3575
gene id: 931890:Ecym_3575
uniprot id: G8JQR1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

931890:Ecym 4596
gene id: 931890:Ecym_4596
uniprot id: G8JSA6
names: Similarity
messages: Belongs to the universal ribosomal protein uS10 family.

931890:Ecym 2792
gene id: 931890:Ecym_2792
uniprot id: G8JQ27
names: Similarity
messages: Belongs to the activator 1 small subunits family.

931890:Ecym 1280
gene id: 931890:Ecym_1280
uniprot id: G8JN56
names: Similarity
messages: Belongs to the citrate synthase family.

931890:Ecym 7225
gene id: 931890:Ecym_7225
uniprot id: G8JW56
names: Similarity
messages: Belongs to the HscB family.

931890:Ecym 5652
gene id: 931890:Ecym_5652
uniprot id: I6NE95
names: Similarity
messages: Belongs to the ELP6 family.

931890:Ecym 2252
gene id: 931890:Ecym_2252
uniprot id: G8JPP3
names: Similarity
messages: Belongs to the bystin family.

931890:Ecym 4780
gene id: 931890:Ecym_4780
uniprot id: G8JSS0
names: Subcellular Location Annotation
messages: Membrane
messages: cell wall

931890:Ecym 5180
gene id: 931890:Ecym_5180
uniprot id: I6ND11
names: Function
names: Similarity
messages: Belongs to the VPS35 family.
messages: Plays a role in vesicular protein sorting.

931890:Ecym 3590
gene id: 931890:Ecym_3590
uniprot id: G8JQS2
names: Function
names: Similarity
messages: Belongs to the KptA/TPT1 family.
messages: Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP-ribose 1''-2'' cyclic phosphate.

931890:Ecym 3103
gene id: 931890:Ecym_3103
uniprot id: G8JR42
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.

931890:Ecym 1258
gene id: 931890:Ecym_1258
uniprot id: G8JN36
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

931890:Ecym 1427
gene id: 931890:Ecym_1427
uniprot id: G8JM84
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 63 family.
messages: Cleaves the distal alpha 1,2-linked glucose residue from the Glc(3)Man(9)GlcNAc(2) oligosaccharide precursor.
messages: Endoplasmic reticulum membrane

931890:Ecym 8095
gene id: 931890:Ecym_8095
uniprot id: G8JX15
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 4217
gene id: 931890:Ecym_4217
uniprot id: G8JTD1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SEC5 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
messages: Component of the exocyst complex.

931890:Ecym 3222
gene id: 931890:Ecym_3222
uniprot id: G8JRF0
names: Similarity
messages: Belongs to the deoxyhypusine synthase family.

931890:Ecym 3042
gene id: 931890:Ecym_3042
uniprot id: G8JQY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Membrane
messages: Required for vacuolar protein sorting.

931890:Ecym 2521
gene id: 931890:Ecym_2521
uniprot id: G8JQ84
names: Similarity
messages: Belongs to the diphosphomevalonate decarboxylase family.

931890:Ecym 1156
gene id: 931890:Ecym_1156
uniprot id: G8JMQ2
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic ribosomal protein eS1 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S).
messages: Cytoplasm

931890:Ecym 2336
gene id: 931890:Ecym_2336
uniprot id: G8JQ73
names: Similarity
messages: Belongs to the cullin family.

931890:Ecym 4178
gene id: 931890:Ecym_4178
uniprot id: G8JTA1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 5265
gene id: 931890:Ecym_5265
uniprot id: I6ND88
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit alpha family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

931890:Ecym 1250
gene id: 931890:Ecym_1250
uniprot id: G8JN29
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 5554
gene id: 931890:Ecym_5554
uniprot id: I6NE02
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.

931890:Ecym 6132
gene id: 931890:Ecym_6132
uniprot id: G8JV45
names: Similarity
messages: Belongs to the OSBP family.

931890:Ecym 6002
gene id: 931890:Ecym_6002
uniprot id: G8JUT1
names: Similarity
messages: Belongs to the proteasome subunit S14 family.

931890:Ecym 2463
gene id: 931890:Ecym_2463
uniprot id: G8JPT1
names: Function
names: Similarity
messages: Belongs to the RNase H family.
messages: Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.

931890:Ecym 1421
gene id: 931890:Ecym_1421
uniprot id: G8JM78
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL24 family.

931890:Ecym 6319
gene id: 931890:Ecym_6319
uniprot id: G8JUB7
names: Similarity
messages: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

931890:Ecym 4644
gene id: 931890:Ecym_4644
uniprot id: G8JSE5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: COPII-coated vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: nuclear pore complex

931890:Ecym 5422
gene id: 931890:Ecym_5422
uniprot id: I6NDN4
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 2149
gene id: 931890:Ecym_2149
uniprot id: G8JNI5
names: Similarity
messages: Belongs to the Tango6 family.

931890:Ecym 3343
gene id: 931890:Ecym_3343
uniprot id: G8JRR3
names: Similarity
messages: Belongs to the PPC synthetase family.

931890:Ecym 2209
gene id: 931890:Ecym_2209
uniprot id: G8JP53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPS2 family.
messages: Component of the spindle pole body (SPB) required for insertion of the nascent SPB into the nuclear envelope and for the proper execution of spindle pole body (SPB) duplication.
messages: Membrane
messages: Nucleus membrane
messages: spindle pole body

931890:Ecym 6079
gene id: 931890:Ecym_6079
uniprot id: G8JUZ7
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DLT1 family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Required for growth under high-pressure and low-temperature conditions.

931890:Ecym 1438
gene id: 931890:Ecym_1438
uniprot id: G8JM93
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the reverse transcriptase family. Telomerase subfamily.
messages: Nucleus
messages: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
messages: telomere

931890:Ecym 5525
gene id: 931890:Ecym_5525
uniprot id: I6NDX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA polymerase beta' chain family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

931890:Ecym 2505
gene id: 931890:Ecym_2505
uniprot id: G8JPW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PDK/BCKDK protein kinase family.
messages: Mitochondrion matrix

931890:Ecym 1346
gene id: 931890:Ecym_1346
uniprot id: G8JNB6
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1481
gene id: 931890:Ecym_1481
uniprot id: G8JMI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

931890:Ecym 3442
gene id: 931890:Ecym_3442
uniprot id: G8JS08
names: Similarity
messages: Belongs to the glycosyltransferase 20 family.

931890:Ecym 2365
gene id: 931890:Ecym_2365
uniprot id: G8JNN0
names: Similarity
messages: Belongs to the AAA ATPase family.

931890:Ecym 2818
gene id: 931890:Ecym_2818
uniprot id: G8JQF1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal Rpo6/eukaryotic RPB6 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 4477
gene id: 931890:Ecym_4477
uniprot id: G8JU14
names: Similarity
messages: Belongs to the TFIIB family.

931890:Ecym 3566
gene id: 931890:Ecym_3566
uniprot id: G8JQQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ISY1 family.
messages: Nucleus

931890:Ecym 4095
gene id: 931890:Ecym_4095
uniprot id: G8JT21
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

931890:Ecym 1297
gene id: 931890:Ecym_1297
uniprot id: G8JN71
names: Similarity
messages: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.

931890:Ecym 1295
gene id: 931890:Ecym_1295
uniprot id: G8JN69
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

931890:Ecym 2247
gene id: 931890:Ecym_2247
uniprot id: G8JPN8
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 6329
gene id: 931890:Ecym_6329
uniprot id: G8JUC5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic60 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Mitochondrion inner membrane

931890:Ecym 3248
gene id: 931890:Ecym_3248
uniprot id: G8JRH2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL31 family.

931890:Ecym 2026
gene id: 931890:Ecym_2026
uniprot id: G8JNY5
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: Required for 3'-end cleavage and polyadenylation of pre-mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle.

931890:Ecym 8035
gene id: 931890:Ecym_8035
uniprot id: G8JWV7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1077
gene id: 931890:Ecym_1077
uniprot id: G8JMC6
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PGAP3 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the lipid remodeling steps of GPI-anchor maturation.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane

931890:Ecym 7278
gene id: 931890:Ecym_7278
uniprot id: G8JWA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8154
gene id: 931890:Ecym_8154
uniprot id: G8JX68
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERCC1/RAD10/SWI10 family.
messages: Nucleus

931890:Ecym 4408
gene id: 931890:Ecym_4408
uniprot id: G8JTV8
names: Similarity
messages: Belongs to the taffazin family.

931890:Ecym 1400
gene id: 931890:Ecym_1400
uniprot id: G8JM58
names: Similarity
messages: Belongs to the methylenetetrahydrofolate reductase family.

931890:Ecym 2419
gene id: 931890:Ecym_2419
uniprot id: G8JP93
names: Cofactor
names: Function
names: Similarity
messages: Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage.
messages: Belongs to the tRNA(His) guanylyltransferase family.
messages: Binds 2 magnesium ions per subunit.

931890:Ecym 2019
gene id: 931890:Ecym_2019
uniprot id: G8JNX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
messages: Mitochondrion matrix

931890:Ecym 5507
gene id: 931890:Ecym_5507
uniprot id: I6NDV8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2095
gene id: 931890:Ecym_2095
uniprot id: G8JPJ9
names: Similarity
messages: Belongs to the threonine synthase family.

931890:Ecym 3240
gene id: 931890:Ecym_3240
uniprot id: G8JRG5
names: Similarity
messages: Belongs to the SRR1 family.

931890:Ecym 2509
gene id: 931890:Ecym_2509
uniprot id: G8JPX2
names: Similarity
messages: Belongs to the PAT1 family.

931890:Ecym 1496
gene id: 931890:Ecym_1496
uniprot id: G8JMK3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal/bacterial/fungal opsin family.
messages: Membrane

931890:Ecym 4133
gene id: 931890:Ecym_4133
uniprot id: G8JT59
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RSA3 family.
messages: Required for efficient biogenesis of the 60S ribosomal subunit.
messages: nucleolus

931890:Ecym 5468
gene id: 931890:Ecym_5468
uniprot id: I6NDS4
names: Similarity
messages: Belongs to the V-ATPase D subunit family.

931890:Ecym 2773
gene id: 931890:Ecym_2773
uniprot id: G8JQ09
names: Domain
names: Similarity
messages: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
messages: The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.

931890:Ecym 3113
gene id: 931890:Ecym_3113
uniprot id: G8JR52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily.
messages: Nucleus

931890:Ecym 3403
gene id: 931890:Ecym_3403
uniprot id: G8JRX0
names: Similarity
messages: Belongs to the small Tim family.

931890:Ecym 8043
gene id: 931890:Ecym_8043
uniprot id: G8JWW5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase inhibitor family.
messages: Forms a one-to-one complex with ATPase to inhibit the enzyme activity completely.
messages: Mitochondrion

931890:Ecym 4110
gene id: 931890:Ecym_4110
uniprot id: G8JT36
names: Similarity
messages: Belongs to the RAD52 family.

931890:Ecym 3363
gene id: 931890:Ecym_3363
uniprot id: G8JRT1
names: Similarity
messages: Belongs to the universal ribosomal protein uL6 family.

931890:Ecym 3548
gene id: 931890:Ecym_3548
uniprot id: G8JQN8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDS family.
messages: Membrane

931890:Ecym 7345
gene id: 931890:Ecym_7345
uniprot id: G8JWG0
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8263
gene id: 931890:Ecym_8263
uniprot id: G8JXH1
names: Function
names: Similarity
messages: Belongs to the heat shock protein 70 family.
messages: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis.

931890:Ecym 7315
gene id: 931890:Ecym_7315
uniprot id: G8JWD5
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS16 family.

931890:Ecym 2155
gene id: 931890:Ecym_2155
uniprot id: G8JNJ1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

931890:Ecym 7314
gene id: 931890:Ecym_7314
uniprot id: G8JWD4
names: Similarity
messages: Belongs to the RRP12 family.

931890:Ecym 5583
gene id: 931890:Ecym_5583
uniprot id: I6NE29
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
messages: Nucleus
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that monomethylates 60S ribosomal protein L42.

931890:Ecym 2566
gene id: 931890:Ecym_2566
uniprot id: G8JQC6
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 2118
gene id: 931890:Ecym_2118
uniprot id: G8JPM2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG2 family.
messages: Catalyzes the reaction which results in unsaturation at C-7 in the B ring of sterols.
messages: Endoplasmic reticulum membrane

931890:Ecym 4358
gene id: 931890:Ecym_4358
uniprot id: G8JTR5
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1036
gene id: 931890:Ecym_1036
uniprot id: G8JM34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein disulfide isomerase family.
messages: Endoplasmic reticulum lumen

931890:Ecym 5401
gene id: 931890:Ecym_5401
uniprot id: I6NDL4
names: Similarity
messages: Belongs to the alpha-ketoglutarate dehydrogenase family.

931890:Ecym 5471
gene id: 931890:Ecym_5471
uniprot id: I6NDS6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAK10 family.
messages: Cytoplasm

931890:Ecym 1230
gene id: 931890:Ecym_1230
uniprot id: G8JN12
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 4254
gene id: 931890:Ecym_4254
uniprot id: G8JTG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF12 family.
messages: Nucleus

931890:Ecym 4446
gene id: 931890:Ecym_4446
uniprot id: G8JTY8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM MRD1 family.
messages: Nucleus

931890:Ecym 4636
gene id: 931890:Ecym_4636
uniprot id: G8JSD7
names: Similarity
messages: Belongs to the glycosyltransferase 2 family.

931890:Ecym 1467
gene id: 931890:Ecym_1467
uniprot id: G8JMH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2288
gene id: 931890:Ecym_2288
uniprot id: G8JPS6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CSM3 family.
messages: Component of the fork protection complex (FPC) consisting of TOF1 and CSM3.
messages: Nucleus
messages: Plays an important role in the control of DNA replication and the maintenance of replication fork stability.

931890:Ecym 6126
gene id: 931890:Ecym_6126
uniprot id: G8JV39
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 6290
gene id: 931890:Ecym_6290
uniprot id: G8JVJ1
names: Subcellular Location Annotation
messages: nuclear pore complex

931890:Ecym 2056
gene id: 931890:Ecym_2056
uniprot id: G8JP13
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 6140
gene id: 931890:Ecym_6140
uniprot id: G8JV52
names: Function
names: Similarity
messages: Belongs to the transaldolase family. Type 1 subfamily.
messages: Catalyzes the rate-limiting step of the non-oxidative phase in the pentose phosphate pathway. Catalyzes the reversible conversion of sedheptulose-7-phosphate and D-glyceraldehyde 3-phosphate into erythrose-4-phosphate and beta-D-fructose 6-phosphate.

931890:Ecym 2373
gene id: 931890:Ecym_2373
uniprot id: G8JNN8
names: Similarity
messages: Belongs to the NXF family.

931890:Ecym 5125
gene id: 931890:Ecym_5125
uniprot id: I6NCW2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
messages: Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis.
messages: Mitochondrion matrix

931890:Ecym 4382
gene id: 931890:Ecym_4382
uniprot id: G8JTT4
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

931890:Ecym 5479
gene id: 931890:Ecym_5479
uniprot id: I6NDT3
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the anamorsin family.
messages: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit RNR2.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion intermembrane space
messages: Monomer. Interacts with TAH18. Interacts with MIA40.
messages: The C-terminal domain binds 2 Fe-S clusters but is otherwise mostly in an intrinsically disordered conformation.
messages: The N-terminal domain has structural similarity with S-adenosyl-L-methionine-dependent methyltransferases, but does not bind S-adenosyl-L-methionine. It is required for correct assembly of the 2 Fe-S clusters.
messages: The twin Cx2C motifs are involved in the recognition by the mitochondrial MIA40-ERV1 disulfide relay system. The formation of 2 disulfide bonds in the Cx2C motifs through dithiol/disulfide exchange reactions effectively traps the protein in the mitochondrial intermembrane space.

931890:Ecym 5257
gene id: 931890:Ecym_5257
uniprot id: I6ND81
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 5651
gene id: 931890:Ecym_5651
uniprot id: I6NE94
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931890:Ecym 8067
gene id: 931890:Ecym_8067
uniprot id: G8JWY9
names: Similarity
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.

931890:Ecym 1094
gene id: 931890:Ecym_1094
uniprot id: G8JME1
names: Similarity
messages: Belongs to the UFD1 family.

931890:Ecym 8177
gene id: 931890:Ecym_8177
uniprot id: G8JX89
names: Similarity
messages: Belongs to the OSBP family.

931890:Ecym 2238
gene id: 931890:Ecym_2238
uniprot id: G8JPN0
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL36 family.

931890:Ecym 8130
gene id: 931890:Ecym_8130
uniprot id: G8JX47
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL39 family.

931890:Ecym 4318
gene id: 931890:Ecym_4318
uniprot id: G8JTM8
names: Function
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase large chain family.
messages: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.

931890:Ecym 8344
gene id: 931890:Ecym_8344
uniprot id: G8JXP6
names: Similarity
messages: Belongs to the AAA ATPase family.

931890:Ecym 2054
gene id: 931890:Ecym_2054
uniprot id: G8JP11
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3280
gene id: 931890:Ecym_3280
uniprot id: G8JRK4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RAD52 family.
messages: Interacts with RAD51 and RAD52.
messages: Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA.
messages: Nucleus

931890:Ecym 1262
gene id: 931890:Ecym_1262
uniprot id: G8JN40
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protoporphyrinogen/coproporphyrinogen oxidase family. Protoporphyrinogen oxidase subfamily.
messages: Binds 1 FAD per subunit.
messages: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.
messages: Mitochondrion inner membrane

931890:Ecym 3108
gene id: 931890:Ecym_3108
uniprot id: G8JR47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM7 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein methyltransferase that trimethylates the N-terminal glycine 'Gly-2' of elongation factor 1-alpha, before also catalyzing the mono- and dimethylation of 'Lys-3'.

931890:Ecym 2663
gene id: 931890:Ecym_2663
uniprot id: G8JNU8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3073
gene id: 931890:Ecym_3073
uniprot id: G8JR16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG12 family.
messages: Forms a conjugate with ATG5.
messages: Membrane
messages: Preautophagosomal structure membrane
messages: Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt), autophagy vesicles formation, mitophagy, and nucleophagy.

931890:Ecym 6001
gene id: 931890:Ecym_6001
uniprot id: G8JUT0
names: Similarity
messages: Belongs to the hexokinase family.

931890:Ecym 5332
gene id: 931890:Ecym_5332
uniprot id: I6NDE9
names: Similarity
messages: Belongs to the universal ribosomal protein uS9 family.

931890:Ecym 2401
gene id: 931890:Ecym_2401
uniprot id: G8JNR6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the WD repeat PRL1/PRL2 family.
messages: Involved in pre-mRNA splicing and required for cell cycle progression at G2/M.
messages: Nucleus

931890:Ecym 2395
gene id: 931890:Ecym_2395
uniprot id: G8JNR0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

931890:Ecym 5578
gene id: 931890:Ecym_5578
uniprot id: I6NE24
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

931890:Ecym 2377
gene id: 931890:Ecym_2377
uniprot id: G8JNP2
names: Similarity
messages: Belongs to the TMA16 family.

931890:Ecym 7432
gene id: 931890:Ecym_7432
uniprot id: G8JWN8
names: Similarity
messages: Belongs to the CBF/MAK21 family.

931890:Ecym 4617
gene id: 931890:Ecym_4617
uniprot id: G8JSC4
names: Function
names: Similarity
messages: Belongs to the PIGL family.
messages: Involved in the second step of GPI biosynthesis. De-N-acetylation of N-acetylglucosaminyl-phosphatidylinositol.

931890:Ecym 3041
gene id: 931890:Ecym_3041
uniprot id: G8JQY6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM12 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. A MMM1 homodimer associates with one molecule of MDM12 on each side in a pairwise head-to-tail manner, and the SMP-LTD domains of MMM1 and MDM12 generate a continuous hydrophobic tunnel for phospholipid trafficking.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all mitochondrial outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids.
messages: Endoplasmic reticulum membrane
messages: Mitochondrion outer membrane

931890:Ecym 2184
gene id: 931890:Ecym_2184
uniprot id: G8JP28
names: Similarity
messages: Belongs to the CBP3 family.

931890:Ecym 5293
gene id: 931890:Ecym_5293
uniprot id: I6NDB3
names: Similarity
messages: Belongs to the RMD1/sif2 family.

931890:Ecym 1204
gene id: 931890:Ecym_1204
uniprot id: G8JMY8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TtcA family. CTU1/NCS6/ATPBD3 subfamily.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

931890:Ecym 5352
gene id: 931890:Ecym_5352
uniprot id: I6NDG9
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

931890:Ecym 1190
gene id: 931890:Ecym_1190
uniprot id: G8JMX4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TPT transporter family. SLC35D subfamily.
messages: Cytoplasmic vesicle membrane
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Homooligomer.
messages: Involved in the import of GDP-mannose from the cytoplasm into the Golgi lumen.
messages: Membrane

931890:Ecym 3598
gene id: 931890:Ecym_3598
uniprot id: G8JQS9
names: Similarity
messages: Belongs to the AHA1 family.

931890:Ecym 8371
gene id: 931890:Ecym_8371
uniprot id: G8JXR8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 3068
gene id: 931890:Ecym_3068
uniprot id: G8JR11
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Fungal FIT2B/SCS3 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization. Involved in phospholipid biosynthesis.
messages: Membrane

931890:Ecym 5477
gene id: 931890:Ecym_5477
uniprot id: I6NDT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOB1 family.
messages: Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm.
messages: nucleolus

931890:Ecym 8069
gene id: 931890:Ecym_8069
uniprot id: G8JWZ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC123 family.
messages: Cytoplasm
messages: Regulates the cell cycle in a nutrient dependent manner.

931890:Ecym 4726
gene id: 931890:Ecym_4726
uniprot id: G8JSM3
names: Similarity
messages: Belongs to the CNOT2/3/5 family.

931890:Ecym 4010
gene id: 931890:Ecym_4010
uniprot id: G8JSU1
names: Similarity
messages: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.

931890:Ecym 4655
gene id: 931890:Ecym_4655
uniprot id: G8JSF5
names: Similarity
messages: Belongs to the indoleamine 2,3-dioxygenase family.

931890:Ecym 5607
gene id: 931890:Ecym_5607
uniprot id: I6NE51
names: Similarity
messages: Belongs to the Luc7 family.

931890:Ecym 4584
gene id: 931890:Ecym_4584
uniprot id: G8JS95
names: Similarity
messages: Belongs to the EFG1/PHD1/stuA family.

931890:Ecym 1422
gene id: 931890:Ecym_1422
uniprot id: G8JM79
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL30 family.

931890:Ecym 2363
gene id: 931890:Ecym_2363
uniprot id: G8JNM9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UbiA prenyltransferase family.
messages: Converts protoheme IX and farnesyl diphosphate to heme O.
messages: Membrane
messages: Mitochondrion membrane

931890:Ecym 5148
gene id: 931890:Ecym_5148
uniprot id: I6NCY3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HIR3 family.
messages: Nucleus

931890:Ecym 4104
gene id: 931890:Ecym_4104
uniprot id: G8JT30
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

931890:Ecym 7320
gene id: 931890:Ecym_7320
uniprot id: G8JWD9
names: Similarity
messages: Belongs to the patched family.

931890:Ecym 4610
gene id: 931890:Ecym_4610
uniprot id: G8JSB7
names: Function
names: Subcellular Location Annotation
messages: Nucleus
messages: This promotes the activity of RNA polymerase II.

931890:Ecym 2600
gene id: 931890:Ecym_2600
uniprot id: G8JQI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DXO/Dom3Z family.
messages: Decapping enzyme for NAD-capped RNAs: specifically hydrolyzes the nicotinamide adenine dinucleotide (NAD) cap from a subset of RNAs by removing the entire NAD moiety from the 5'-end of an NAD-capped RNA.
messages: Nucleus

931890:Ecym 1210
gene id: 931890:Ecym_1210
uniprot id: G8JMZ3
names: Similarity
messages: Belongs to the 5'-AMP-activated protein kinase beta subunit family.

931890:Ecym 7312
gene id: 931890:Ecym_7312
uniprot id: G8JWD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the adaptor complexes small subunit family.
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex.

931890:Ecym 2592
gene id: 931890:Ecym_2592
uniprot id: G8JQH4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the NadC/ModD family.
messages: Hexamer formed by 3 homodimers.
messages: Involved in the catabolism of quinolinic acid (QA).

931890:Ecym 1112
gene id: 931890:Ecym_1112
uniprot id: G8JML1
names: Similarity
messages: Belongs to the nucleosome assembly protein (NAP) family.

931890:Ecym 7022
gene id: 931890:Ecym_7022
uniprot id: G8JVL4
names: Subcellular Location Annotation
messages: Mitochondrion inner membrane

931890:Ecym 8045
gene id: 931890:Ecym_8045
uniprot id: G8JWW7
names: Function
names: Similarity
messages: Belongs to the alpha-IPM synthase/homocitrate synthase family. Homocitrate synthase LYS20/LYS21 subfamily.
messages: Catalyzes the aldol-type condensation of 2-oxoglutarate with acetyl-CoA to yield homocitrate. Carries out the first step of the alpha-aminoadipate (AAA) lysine biosynthesis pathway.

931890:Ecym 1088
gene id: 931890:Ecym_1088
uniprot id: G8JMD6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 3370
gene id: 931890:Ecym_3370
uniprot id: G8JRT8
names: Similarity
messages: Belongs to the prokaryotic/mitochondrial release factor family.

931890:Ecym 8065
gene id: 931890:Ecym_8065
uniprot id: G8JWY7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNA polymerase beta' chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: Nucleus

931890:Ecym 2105
gene id: 931890:Ecym_2105
uniprot id: G8JPK9
names: Similarity
messages: Belongs to the peptidase S8 family.

931890:Ecym 4516
gene id: 931890:Ecym_4516
uniprot id: G8JU50
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ7 family.
messages: Binds 2 iron ions per subunit.
messages: Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Mitochondrion inner membrane

931890:Ecym 7108
gene id: 931890:Ecym_7108
uniprot id: G8JVU5
names: Similarity
messages: Belongs to the SDO1/SBDS family.

931890:Ecym 8184
gene id: 931890:Ecym_8184
uniprot id: G8JX96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CENP-O/MCM21 family.
messages: Nucleus

931890:Ecym 3104
gene id: 931890:Ecym_3104
uniprot id: G8JR43
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS30 family.

931890:Ecym 2148
gene id: 931890:Ecym_2148
uniprot id: G8JNI4
names: Similarity
messages: Belongs to the heat shock protein 90 family.

931890:Ecym 2304
gene id: 931890:Ecym_2304
uniprot id: G8JQ44
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase S26 family. IMP2 subfamily.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5430
gene id: 931890:Ecym_5430
uniprot id: I6NDP2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPC9 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 6041
gene id: 931890:Ecym_6041
uniprot id: G8JUW6
names: Similarity
messages: Belongs to the TRM112 family.

931890:Ecym 4069
gene id: 931890:Ecym_4069
uniprot id: G8JSZ6
names: Similarity
messages: Belongs to the proteasome subunit S11 family.

931890:Ecym 6267
gene id: 931890:Ecym_6267
uniprot id: G8JVG9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 5460
gene id: 931890:Ecym_5460
uniprot id: I6NDR7
names: Similarity
messages: Belongs to the PIAS family.

931890:Ecym 5356
gene id: 931890:Ecym_5356
uniprot id: I6NDH2
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

931890:Ecym 5186
gene id: 931890:Ecym_5186
uniprot id: I6ND16
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFIIE beta subunit family.
messages: Nucleus
messages: Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
messages: Tetramer of two alpha and two beta chains.

931890:Ecym 2623
gene id: 931890:Ecym_2623
uniprot id: G8JQK3
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MDM10 family.
messages: Component of the ER-mitochondria encounter structure (ERMES) or MDM complex, composed of MMM1, MDM10, MDM12 and MDM34. Associates with the mitochondrial outer membrane sorting assembly machinery SAM(core) complex.
messages: Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the receptor TOM22 and small TOM proteins. Can associate with the SAM(core) complex as well as the MDM12-MMM1 complex, both involved in late steps of the major beta-barrel assembly pathway, that is responsible for biogenesis of all outer membrane beta-barrel proteins. May act as a switch that shuttles between both complexes and channels precursor proteins into the TOM40-specific pathway. Plays a role in mitochondrial morphology and in the inheritance of mitochondria.
messages: Lacks alpha-helical transmembrane segments, suggesting that it resides in the membrane via beta-sheet conformations similar to those predicted for other outer membrane proteins and porin.
messages: Mitochondrion outer membrane

931890:Ecym 5078
gene id: 931890:Ecym_5078
uniprot id: I6NCS6
names: Function
names: Similarity
messages: Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.
messages: Belongs to the adaptor complexes large subunit family.

931890:Ecym 5446
gene id: 931890:Ecym_5446
uniprot id: I6NDQ5
names: Similarity
messages: Belongs to the PHF5 family.

931890:Ecym 5149
gene id: 931890:Ecym_5149
uniprot id: I6NCY4
names: Similarity
messages: Belongs to the homoserine dehydrogenase family.

931890:Ecym 5451
gene id: 931890:Ecym_5451
uniprot id: I6NDQ8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ISN1 family.
messages: Homotetramer.
messages: IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation.

931890:Ecym 4182
gene id: 931890:Ecym_4182
uniprot id: G8JTA5
names: Similarity
messages: Belongs to the phosducin family.

931890:Ecym 7117
gene id: 931890:Ecym_7117
uniprot id: G8JVV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCR10/QCR9 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits.
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8137
gene id: 931890:Ecym_8137
uniprot id: G8JX54
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ELO family.
messages: Membrane

931890:Ecym 5530
gene id: 931890:Ecym_5530
uniprot id: I6NDX8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TVP23 family.
messages: Golgi apparatus membrane
messages: Golgi membrane protein involved in vesicular trafficking.
messages: Membrane

931890:Ecym 2246
gene id: 931890:Ecym_2246
uniprot id: G8JPN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRM NCBP2 family.
messages: Nucleus

931890:Ecym 5535
gene id: 931890:Ecym_5535
uniprot id: I6NDY3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TFB5 family.
messages: Component of the 7-subunit TFIIH core complex.
messages: In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape.
messages: Nucleus

931890:Ecym 8304
gene id: 931890:Ecym_8304
uniprot id: G8JXK8
names: Similarity
messages: Belongs to the beclin family.

931890:Ecym 1182
gene id: 931890:Ecym_1182
uniprot id: G8JMW8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Mitochondrion inner membrane

931890:Ecym 2785
gene id: 931890:Ecym_2785
uniprot id: G8JQ20
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the DHBP synthase family.
messages: Binds 2 divalent metal cations per subunit. Magnesium or manganese.
messages: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.
messages: Homodimer.

931890:Ecym 8189
gene id: 931890:Ecym_8189
uniprot id: G8JXA0
names: Similarity
messages: Belongs to the Tom22 family.

931890:Ecym 3509
gene id: 931890:Ecym_3509
uniprot id: G8JS68
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).

931890:Ecym 5364
gene id: 931890:Ecym_5364
uniprot id: I6NDI0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NST1 family.
messages: Cytoplasm
messages: May act as a negative regulator of salt tolerance.

931890:Ecym 7033
gene id: 931890:Ecym_7033
uniprot id: G8JVM5
names: Similarity
messages: Belongs to the TSR2 family.

931890:Ecym 5377
gene id: 931890:Ecym_5377
uniprot id: I6NDJ0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 7207
gene id: 931890:Ecym_7207
uniprot id: G8JW40
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC4 family.
messages: Nucleus

931890:Ecym 7146
gene id: 931890:Ecym_7146
uniprot id: G8JVY0
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 1241
gene id: 931890:Ecym_1241
uniprot id: G8JN22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AB hydrolase superfamily. LDAH family.
messages: Lipid droplet

931890:Ecym 7144
gene id: 931890:Ecym_7144
uniprot id: G8JVX8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

931890:Ecym 1459
gene id: 931890:Ecym_1459
uniprot id: G8JMG8
names: Similarity
messages: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.

931890:Ecym 4690
gene id: 931890:Ecym_4690
uniprot id: G8JSI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RecA family. RAD51 subfamily.
messages: Nucleus
messages: Required both for recombination and for the repair of DNA damage caused by X-rays.

931890:Ecym 2299
gene id: 931890:Ecym_2299
uniprot id: G8JQ39
names: Similarity
messages: Belongs to the CCS1 family.

931890:Ecym 8234
gene id: 931890:Ecym_8234
uniprot id: G8JXE5
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS27 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 2274
gene id: 931890:Ecym_2274
uniprot id: G8JPR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat ARPC1 family.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: actin patch

931890:Ecym 7428
gene id: 931890:Ecym_7428
uniprot id: G8JWN6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OS-9 family.
messages: Endoplasmic reticulum membrane

931890:Ecym 5215
gene id: 931890:Ecym_5215
uniprot id: I6ND42
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Component of the cytoplasmic LSM1-LSM7 complex which is involved in mRNA degradation.
messages: Component of the heptameric LSM1-LSM7 complex that forms a seven-membered ring structure with a donut shape.
messages: Cytoplasm
messages: P-body

931890:Ecym 2125
gene id: 931890:Ecym_2125
uniprot id: G8JNG2
names: Function
names: Similarity
messages: Belongs to the cyclin family.
messages: G1/S-specific cyclin essential for the control of the cell cycle at the G1/S (start) transition.

931890:Ecym 2652
gene id: 931890:Ecym_2652
uniprot id: G8JNT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

931890:Ecym 8281
gene id: 931890:Ecym_8281
uniprot id: G8JXI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

931890:Ecym 7286
gene id: 931890:Ecym_7286
uniprot id: G8JWA9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

931890:Ecym 5240
gene id: 931890:Ecym_5240
uniprot id: I6ND65
names: Similarity
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

931890:Ecym 8084
gene id: 931890:Ecym_8084
uniprot id: G8JX05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SFT2 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: Nonessential protein required for the fusion of transport vesicles derived from the endocytic pathway with the Golgi complex.

931890:Ecym 2157
gene id: 931890:Ecym_2157
uniprot id: G8JNJ3
names: Similarity
messages: Belongs to the syntaxin family.

931890:Ecym 1533
gene id: 931890:Ecym_1533
uniprot id: G8JMT8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eukaryotic PMM family.
messages: Cytoplasm
messages: Homodimer.
messages: Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions.

931890:Ecym 1121
gene id: 931890:Ecym_1121
uniprot id: G8JMM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily.
messages: Nucleus
messages: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

931890:Ecym 8252
gene id: 931890:Ecym_8252
uniprot id: G8JXG1
names: Similarity
messages: Belongs to the LTV1 family.

931890:Ecym 1320
gene id: 931890:Ecym_1320
uniprot id: G8JN91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVF1 family.
messages: Cytoplasm

931890:Ecym 6362
gene id: 931890:Ecym_6362
uniprot id: G8JUF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the unc-50 family.
messages: Membrane

931890:Ecym 1470
gene id: 931890:Ecym_1470
uniprot id: G8JMH9
names: Similarity
messages: Belongs to the MBF1 family.

931890:Ecym 4075
gene id: 931890:Ecym_4075
uniprot id: G8JT02
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 3044
gene id: 931890:Ecym_3044
uniprot id: G8JQY9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF4 family.
messages: Functions as a component of the DNA-binding general transcription factor complex TFIID. Binding of TFIID to a promoter (with or without TATA element) is the initial step in pre-initiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modification (histone acetylation by TAF1), facilitation of DNA opening and initiation of transcription.
messages: Nucleus

931890:Ecym 4147
gene id: 931890:Ecym_4147
uniprot id: G8JT72
names: Similarity
messages: Belongs to the eIF-2B gamma/epsilon subunits family.

931890:Ecym 4058
gene id: 931890:Ecym_4058
uniprot id: G8JSY6
names: Similarity
messages: Belongs to the putative lipase ROG1 family.

931890:Ecym 8101
gene id: 931890:Ecym_8101
uniprot id: G8JX21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UQCRQ/QCR8 family.
messages: Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 3 respiratory subunits cytochrome b, cytochrome c1 and Rieske protein, 2 core protein subunits, and additional low-molecular weight protein subunits. The complex exists as an obligatory dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with cytochrome c oxidase (complex IV, CIV).
messages: Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 3525
gene id: 931890:Ecym_3525
uniprot id: G8JQL9
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

931890:Ecym 4492
gene id: 931890:Ecym_4492
uniprot id: G8JU28
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6270
gene id: 931890:Ecym_6270
uniprot id: G8JVH2
names: Similarity
messages: In the N-terminal section; belongs to the FGAMS family.

931890:Ecym 1303
gene id: 931890:Ecym_1303
uniprot id: G8JN77
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8274
gene id: 931890:Ecym_8274
uniprot id: G8JXI2
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

931890:Ecym 4154
gene id: 931890:Ecym_4154
uniprot id: G8JT78
names: Function
names: Similarity
messages: Belongs to the type IA topoisomerase family.
messages: Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand.

931890:Ecym 2653
gene id: 931890:Ecym_2653
uniprot id: G8JNT9
names: Similarity
names: Subunit
messages: Belongs to the aerobic coproporphyrinogen-III oxidase family.
messages: Homodimer.

931890:Ecym 2707
gene id: 931890:Ecym_2707
uniprot id: G8JPE7
names: Similarity
messages: Belongs to the SUN family.

931890:Ecym 4537
gene id: 931890:Ecym_4537
uniprot id: G8JU70
names: Similarity
messages: Belongs to the universal ribosomal protein uL23 family.

931890:Ecym 4208
gene id: 931890:Ecym_4208
uniprot id: G8JTC2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5559
gene id: 931890:Ecym_5559
uniprot id: I6NE07
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 4227
gene id: 931890:Ecym_4227
uniprot id: G8JTE1
names: Function
names: Similarity
messages: Belongs to the CWC15 family.
messages: Involved in pre-mRNA splicing.

931890:Ecym 7262
gene id: 931890:Ecym_7262
uniprot id: G8JW91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 4390
gene id: 931890:Ecym_4390
uniprot id: G8JTU1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC2 subfamily.
messages: Nucleus

931890:Ecym 2460
gene id: 931890:Ecym_2460
uniprot id: G8JPS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRS1 family.
messages: Involved in ribosomal large subunit assembly.
messages: Nucleus

931890:Ecym 2091
gene id: 931890:Ecym_2091
uniprot id: G8JPJ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the IMPACT family.
messages: Cytoplasm

931890:Ecym 2310
gene id: 931890:Ecym_2310
uniprot id: G8JQ50
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1131
gene id: 931890:Ecym_1131
uniprot id: G8JMM8
names: Similarity
messages: Belongs to the peptidase M28 family. M28B subfamily.

931890:Ecym 7294
gene id: 931890:Ecym_7294
uniprot id: G8JWB7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. GMF subfamily.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 4775
gene id: 931890:Ecym_4775
uniprot id: G8JSR5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: ATP-dependent RNA helicase involved in 40S ribosomal subunit biogenesis. Required for the processing and cleavage of 35S pre-rRNA at sites A0, A1, and A2, leading to mature 18S rRNA.
messages: Belongs to the DEAD box helicase family. DDX18/HAS1 subfamily.
messages: nucleolus

931890:Ecym 3306
gene id: 931890:Ecym_3306
uniprot id: G8JRM8
names: Cofactor
names: Function
names: Similarity
messages: Aminopeptidase that preferentially cleaves di- and tripeptides. Also has low epoxide hydrolase activity (in vitro). Can hydrolyze the epoxide leukotriene LTA(4) but it forms preferentially 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid rather than the cytokine leukotriene B(4) as the product compared to the homologous mammalian enzyme (in vitro).
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 2022
gene id: 931890:Ecym_2022
uniprot id: G8JNY1
names: Function
names: Similarity
messages: Belongs to the eukaryotic initiation factor 4E family.
messages: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

931890:Ecym 4670
gene id: 931890:Ecym_4670
uniprot id: G8JSG9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC2 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins.

931890:Ecym 2161
gene id: 931890:Ecym_2161
uniprot id: G8JNJ7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the fungal TPase family.
messages: First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end.
messages: Heterodimer. The mRNA-capping enzyme is composed of two separate chains alpha and beta, respectively a mRNA guanylyltransferase and an mRNA 5'-triphosphate monophosphatase.
messages: Nucleus

931890:Ecym 2175
gene id: 931890:Ecym_2175
uniprot id: G8JNL0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the transient receptor potential (TRP) ion channel family.
messages: Membrane

931890:Ecym 5604
gene id: 931890:Ecym_5604
uniprot id: I6NE48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SWP1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

931890:Ecym 4472
gene id: 931890:Ecym_4472
uniprot id: G8JU09
names: Similarity
messages: Belongs to the SEC3 family.

931890:Ecym 4156
gene id: 931890:Ecym_4156
uniprot id: G8JT80
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the COQ4 family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Component of the coenzyme Q biosynthetic pathway. May play a role in organizing a multi-subunit COQ enzyme complex required for coenzyme Q biosynthesis. Required for steady-state levels of other COQ polypeptides.
messages: Mitochondrion inner membrane

931890:Ecym 1464
gene id: 931890:Ecym_1464
uniprot id: G8JMH3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the enhancer of polycomb family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M.
messages: Nucleus

931890:Ecym 5193
gene id: 931890:Ecym_5193
uniprot id: I6ND22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPB4 RNA polymerase subunit family.
messages: Nucleus

931890:Ecym 6011
gene id: 931890:Ecym_6011
uniprot id: G8JUU0
names: Similarity
messages: Belongs to the ribonucleoside diphosphate reductase small chain family.

931890:Ecym 1026
gene id: 931890:Ecym_1026
uniprot id: G8JM24
names: Similarity
messages: Belongs to the RPAP1 family.

931890:Ecym 2341
gene id: 931890:Ecym_2341
uniprot id: G8JQ75
names: Similarity
messages: Belongs to the PPP phosphatase family.

931890:Ecym 8175
gene id: 931890:Ecym_8175
uniprot id: G8JX87
names: Similarity
messages: In the C-terminal section; belongs to the NAD synthetase family.

931890:Ecym 5609
gene id: 931890:Ecym_5609
uniprot id: I6NE53
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NUR1 family.
messages: Member of a perinuclear network that controls recombination at multiple loci to maintain genome stability. Required for rDNA repeat stability.
messages: Membrane
messages: Nucleus membrane

931890:Ecym 2434
gene id: 931890:Ecym_2434
uniprot id: G8JPA6
names: Similarity
messages: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

931890:Ecym 6272
gene id: 931890:Ecym_6272
uniprot id: G8JVH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OXA1/ALB3/YidC family.
messages: Membrane

931890:Ecym 5321
gene id: 931890:Ecym_5321
uniprot id: I6NDD8
names: Similarity
messages: Belongs to the peptidase S10 family.

931890:Ecym 2515
gene id: 931890:Ecym_2515
uniprot id: G8JPX8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 12 family.
messages: Nucleus

931890:Ecym 6260
gene id: 931890:Ecym_6260
uniprot id: G8JVG3
names: Caution
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrial transcription factor that confers selective promoter recognition on the core subunit of the yeast mitochondrial RNA polymerase. Interacts with DNA in a non-specific manner.

931890:Ecym 3545
gene id: 931890:Ecym_3545
uniprot id: G8JQN5
names: Similarity
messages: Belongs to the MNN1/MNT family.

931890:Ecym 4452
gene id: 931890:Ecym_4452
uniprot id: G8JTZ4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NRAP family.
messages: nucleolus

931890:Ecym 5526
gene id: 931890:Ecym_5526
uniprot id: I6NDX5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DSS1/SEM1 family.
messages: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins.
messages: Nucleus

931890:Ecym 4680
gene id: 931890:Ecym_4680
uniprot id: G8JSH9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS8 family.

931890:Ecym 7466
gene id: 931890:Ecym_7466
uniprot id: G8JWS0
names: Similarity
messages: Belongs to the AB hydrolase superfamily. MetX family.

931890:Ecym 5062
gene id: 931890:Ecym_5062
uniprot id: I6NCR0
names: Similarity
messages: Belongs to the V-ATPase E subunit family.

931890:Ecym 8194
gene id: 931890:Ecym_8194
uniprot id: G8JXA5
names: Similarity
messages: Belongs to the LSM12 family.

931890:Ecym 1227
gene id: 931890:Ecym_1227
uniprot id: G8JN10
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1511
gene id: 931890:Ecym_1511
uniprot id: G8JMR9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL22 family.

931890:Ecym 5585
gene id: 931890:Ecym_5585
uniprot id: I6NE31
names: Subcellular Location Annotation
messages: Peroxisome membrane

931890:Ecym 6322
gene id: 931890:Ecym_6322
uniprot id: G8JUB8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC3 subfamily.
messages: Nucleus

931890:Ecym 6412
gene id: 931890:Ecym_6412
uniprot id: G8JUK4
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.

931890:Ecym 2815
gene id: 931890:Ecym_2815
uniprot id: G8JQE8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycogen debranching enzyme family.
messages: Cytoplasm
messages: Multifunctional enzyme acting as 1,4-alpha-D-glucan:1,4-alpha-D-glucan 4-alpha-D-glycosyltransferase and amylo-1,6-glucosidase in glycogen degradation.

931890:Ecym 5394
gene id: 931890:Ecym_5394
uniprot id: I6NDK7
names: Similarity
messages: Belongs to the universal ribosomal protein uL13 family.

931890:Ecym 3061
gene id: 931890:Ecym_3061
uniprot id: G8JR04
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SLX1 family.
messages: Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.
messages: Forms a heterodimer with SLX4.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Nucleus

931890:Ecym 4109
gene id: 931890:Ecym_4109
uniprot id: G8JT35
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NDC1 family.
messages: Membrane
messages: Nucleus membrane
messages: nuclear pore complex

931890:Ecym 4641
gene id: 931890:Ecym_4641
uniprot id: G8JSE2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ferredoxin--NADP reductase type 1 family.
messages: Mitochondrion

931890:Ecym 4525
gene id: 931890:Ecym_4525
uniprot id: G8JU59
names: Similarity
messages: Belongs to the syntaxin family.

931890:Ecym 7327
gene id: 931890:Ecym_7327
uniprot id: G8JWE6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAT1 family.
messages: Catalytic component of the histone acetylase B (HAT-B) complex. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
messages: Component of the HAT-B complex composed of at least HAT1 and HAT2. The HAT-B complex binds to histone H4 tail.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 7413
gene id: 931890:Ecym_7413
uniprot id: G8JWM3
names: Similarity
messages: Belongs to the AP endonuclease 2 family.

931890:Ecym 7199
gene id: 931890:Ecym_7199
uniprot id: G8JW32
names: Similarity
messages: Belongs to the GcvT family. CAF17 subfamily.

931890:Ecym 1098
gene id: 931890:Ecym_1098
uniprot id: G8JME5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YIF1 family.
messages: Endoplasmic reticulum membrane
messages: Golgi apparatus membrane
messages: Has a role in transport between endoplasmic reticulum and Golgi.
messages: Membrane

931890:Ecym 7450
gene id: 931890:Ecym_7450
uniprot id: G8JWQ4
names: Function
names: Similarity
messages: Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
messages: Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.

931890:Ecym 7194
gene id: 931890:Ecym_7194
uniprot id: G8JW27
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 17 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 2112
gene id: 931890:Ecym_2112
uniprot id: G8JPL6
names: Similarity
messages: Belongs to the uridine kinase family.

931890:Ecym 5061
gene id: 931890:Ecym_5061
uniprot id: I6NCQ9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2407
gene id: 931890:Ecym_2407
uniprot id: G8JP82
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATG5 family.
messages: Conjugated with ATG12.
messages: Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation.
messages: Membrane
messages: Preautophagosomal structure membrane

931890:Ecym 7042
gene id: 931890:Ecym_7042
uniprot id: G8JVN3
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8285
gene id: 931890:Ecym_8285
uniprot id: G8JXJ1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2724
gene id: 931890:Ecym_2724
uniprot id: G8JPF9
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

931890:Ecym 7012
gene id: 931890:Ecym_7012
uniprot id: G8JVK4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the calcineurin regulatory subunit family.
messages: Composed of a catalytic subunit (A) and a regulatory subunit (B).
messages: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity.

931890:Ecym 7027
gene id: 931890:Ecym_7027
uniprot id: G8JVL9
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 3438
gene id: 931890:Ecym_3438
uniprot id: G8JS04
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG14 family.
messages: Vacuole membrane

931890:Ecym 4326
gene id: 931890:Ecym_4326
uniprot id: G8JTN6
names: Function
names: Similarity
messages: Belongs to the RGI1 family.
messages: Involved in the control of energetic metabolism and significantly contribute to cell fitness, especially under respiratory growth conditions.

931890:Ecym 4403
gene id: 931890:Ecym_4403
uniprot id: G8JTV4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the dUTPase family.
messages: Homotrimer.
messages: This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

931890:Ecym 3273
gene id: 931890:Ecym_3273
uniprot id: G8JRJ7
names: Similarity
messages: Belongs to the peptidase M16 family.

931890:Ecym 8179
gene id: 931890:Ecym_8179
uniprot id: G8JX91
names: Similarity
messages: Belongs to the NOP10 family.

931890:Ecym 8260
gene id: 931890:Ecym_8260
uniprot id: G8JXG8
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 4538
gene id: 931890:Ecym_4538
uniprot id: G8JU71
names: Function
names: Similarity
messages: Belongs to the RNA polymerase beta chain family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.

931890:Ecym 4489
gene id: 931890:Ecym_4489
uniprot id: G8JU25
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

931890:Ecym 1375
gene id: 931890:Ecym_1375
uniprot id: G8JNE4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Common component of the spliceosome and rRNA processing machinery.
messages: nucleolus

931890:Ecym 5173
gene id: 931890:Ecym_5173
uniprot id: I6ND05
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NAC-alpha family.
messages: Component of the nascent polypeptide-associated complex (NAC), a dynamic component of the ribosomal exit tunnel, protecting the emerging polypeptides from interaction with other cytoplasmic proteins to ensure appropriate nascent protein targeting. The NAC complex also promotes mitochondrial protein import by enhancing productive ribosome interactions with the outer mitochondrial membrane and blocks the inappropriate interaction of ribosomes translating non-secretory nascent polypeptides with translocation sites in the membrane of the endoplasmic reticulum. EGD2 may also be involved in transcription regulation.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 2111
gene id: 931890:Ecym_2111
uniprot id: G8JPL5
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4082
gene id: 931890:Ecym_4082
uniprot id: G8JT08
names: Function
names: Similarity
messages: Belongs to the methyltransferase superfamily. LCMT family.
messages: Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha-leucine ester residues.

931890:Ecym 3066
gene id: 931890:Ecym_3066
uniprot id: G8JR09
names: Function
messages: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.

931890:Ecym 3443
gene id: 931890:Ecym_3443
uniprot id: G8JS09
names: Similarity
messages: Belongs to the PP2C family.

931890:Ecym 4073
gene id: 931890:Ecym_4073
uniprot id: G8JT00
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPT5 family.
messages: Nucleus
messages: The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.

931890:Ecym 4637
gene id: 931890:Ecym_4637
uniprot id: G8JSD8
names: Similarity
messages: Belongs to the complex I LYR family. SDHAF1 subfamily.

931890:Ecym 8088
gene id: 931890:Ecym_8088
uniprot id: G8JX09
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the KAE1 / TsaD family.
messages: Binds 1 divalent metal cation per subunit.
messages: Component of the EKC/KEOPS complex composed of at least BUD32, CGI121, GON7, KAE1 and PCC1; the whole complex dimerizes.
messages: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transcriptional coactivators.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 1087
gene id: 931890:Ecym_1087
uniprot id: G8JMD5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 7134
gene id: 931890:Ecym_7134
uniprot id: G8JVW9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SHO1 family.
messages: Cell membrane
messages: Forms homooligomers.
messages: Membrane
messages: Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity.

931890:Ecym 5650
gene id: 931890:Ecym_5650
uniprot id: I6NE93
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 1035
gene id: 931890:Ecym_1035
uniprot id: G8JM33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MGR1 family.
messages: Membrane

931890:Ecym 8320
gene id: 931890:Ecym_8320
uniprot id: G8JXM4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM41 family.
messages: Mitochondrion

931890:Ecym 5326
gene id: 931890:Ecym_5326
uniprot id: I6NDE3
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 2513
gene id: 931890:Ecym_2513
uniprot id: G8JPX6
names: Similarity
messages: Belongs to the universal ribosomal protein uS19 family.

931890:Ecym 3454
gene id: 931890:Ecym_3454
uniprot id: G8JS19
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the transketolase family.
messages: Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).
messages: Binds 1 thiamine pyrophosphate per subunit.
messages: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
messages: Homodimer.

931890:Ecym 2451
gene id: 931890:Ecym_2451
uniprot id: G8JPC1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 6098
gene id: 931890:Ecym_6098
uniprot id: G8JV15
names: Similarity
messages: Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily.

931890:Ecym 4376
gene id: 931890:Ecym_4376
uniprot id: G8JTS8
names: Similarity
messages: Belongs to the TPA1 family.

931890:Ecym 5231
gene id: 931890:Ecym_5231
uniprot id: I6ND57
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4575
gene id: 931890:Ecym_4575
uniprot id: G8JS86
names: Function
names: Similarity
messages: Belongs to the BLI1 family.
messages: Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.

931890:Ecym 3385
gene id: 931890:Ecym_3385
uniprot id: G8JRV3
names: Similarity
messages: Belongs to the protein prenyltransferase subunit alpha family.

931890:Ecym 6357
gene id: 931890:Ecym_6357
uniprot id: G8JUF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM16/PAM16 family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation.
messages: Mitochondrion inner membrane

931890:Ecym 4081
gene id: 931890:Ecym_4081
uniprot id: G8JT07
names: Similarity
messages: Belongs to the TAF11 family.

931890:Ecym 4783
gene id: 931890:Ecym_4783
uniprot id: G8JSS3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 4436
gene id: 931890:Ecym_4436
uniprot id: G8JTX9
names: Subcellular Location Annotation
messages: Nucleus membrane

931890:Ecym 8279
gene id: 931890:Ecym_8279
uniprot id: G8JXI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ORC3 family.
messages: Nucleus

931890:Ecym 6288
gene id: 931890:Ecym_6288
uniprot id: G8JVI9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily.
messages: Endoplasmic reticulum membrane
messages: Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose.
messages: Membrane

931890:Ecym 8383
gene id: 931890:Ecym_8383
uniprot id: G8JXS9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 5'-3' exonuclease family.
messages: Cytoplasm
messages: Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins.

931890:Ecym 1299
gene id: 931890:Ecym_1299
uniprot id: G8JN73
names: Similarity
messages: Belongs to the DCC1 family.

931890:Ecym 2546
gene id: 931890:Ecym_2546
uniprot id: G8JQA8
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the SGF11 family.
messages: Component of the 1.8 MDa SAGA transcription coactivator-HAT complex. SAGA is built of 5 distinct domains with specialized functions. Within the SAGA complex, SUS1, SGF11, SGF73 and UBP8 form an additional subcomplex of SAGA called the DUB module (deubiquitination module). Interacts directly with SGF73, SUS1 and UBP8.
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complex SAGA. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and promoter selectivity, interaction with transcription activators, and chromatin modification through histone acetylation and deubiquitination. SAGA acetylates nucleosomal histone H3 to some extent (to form H3K9ac, H3K14ac, H3K18ac and H3K23ac). SAGA interacts with DNA via upstream activating sequences (UASs). Involved in transcriptional regulation of a subset of SAGA-regulated genes. Within the SAGA complex, participates in a subcomplex, that specifically deubiquitinates histones H2B.
messages: Nucleus
messages: The C-terminal SGF11-type zinc-finger domain together with the C-terminal catalytic domain of UBP8 forms the 'catalytic lobe' of the SAGA deubiquitination module.
messages: The long N-terminal helix forms part of the 'assembly lobe' of the SAGA deubiquitination module.

931890:Ecym 5300
gene id: 931890:Ecym_5300
uniprot id: I6NDC0
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

931890:Ecym 1491
gene id: 931890:Ecym_1491
uniprot id: G8JMJ8
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL20 family.

931890:Ecym 3024
gene id: 931890:Ecym_3024
uniprot id: G8JQX1
names: Similarity
messages: Belongs to the UPF0507 family.

931890:Ecym 2568
gene id: 931890:Ecym_2568
uniprot id: G8JQC7
names: Similarity
messages: Belongs to the PGA52 family.

931890:Ecym 3241
gene id: 931890:Ecym_3241
uniprot id: G8JRG6
names: Function
names: Similarity
messages: 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (PRS2, PRS3, PRS4 and PRS5).
messages: Belongs to the ribose-phosphate pyrophosphokinase family.

931890:Ecym 2704
gene id: 931890:Ecym_2704
uniprot id: G8JPE4
names: Subcellular Location Annotation
messages: Cytoplasm

931890:Ecym 5455
gene id: 931890:Ecym_5455
uniprot id: I6NDR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Involved in pre-mRNA splicing. Binds and is required for the stability of snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site. Involved in cap modification.
messages: Nucleus

931890:Ecym 2167
gene id: 931890:Ecym_2167
uniprot id: G8JNK3
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4788
gene id: 931890:Ecym_4788
uniprot id: G8JSS7
names: Similarity
messages: Belongs to the eIF-2-alpha family.

931890:Ecym 5219
gene id: 931890:Ecym_5219
uniprot id: I6ND46
names: Cofactor
names: Similarity
messages: Belongs to the ribulose-phosphate 3-epimerase family.
messages: Binds 1 divalent metal cation per subunit.

931890:Ecym 4558
gene id: 931890:Ecym_4558
uniprot id: G8JU89
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex ASK1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 5636
gene id: 931890:Ecym_5636
uniprot id: I6NE80
names: Similarity
names: Subunit
messages: Belongs to the AlaDH/PNT family.
messages: Monomer.

931890:Ecym 6084
gene id: 931890:Ecym_6084
uniprot id: G8JV01
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL15 family.

931890:Ecym 2531
gene id: 931890:Ecym_2531
uniprot id: G8JQ94
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 4710
gene id: 931890:Ecym_4710
uniprot id: G8JSK8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-13 family.
messages: Membrane
messages: Peroxisome membrane

931890:Ecym 5097
gene id: 931890:Ecym_5097
uniprot id: I6NCT9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.
messages: Belongs to the NMD3 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 4083
gene id: 931890:Ecym_4083
uniprot id: G8JT09
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PPP phosphatase family. PP-Z subfamily.
messages: Cytoplasm

931890:Ecym 4732
gene id: 931890:Ecym_4732
uniprot id: G8JSM8
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 7092
gene id: 931890:Ecym_7092
uniprot id: G8JVS9
names: Similarity
messages: Belongs to the small GTPase superfamily. Arf family.

931890:Ecym 2178
gene id: 931890:Ecym_2178
uniprot id: G8JNL2
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family.

931890:Ecym 2100
gene id: 931890:Ecym_2100
uniprot id: G8JPK4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase M76 family.
messages: Has a dual role in the assembly of mitochondrial ATPase.
messages: Mitochondrion inner membrane

931890:Ecym 4252
gene id: 931890:Ecym_4252
uniprot id: G8JTG4
names: Similarity
messages: Belongs to the cullin family.

931890:Ecym 4697
gene id: 931890:Ecym_4697
uniprot id: G8JSJ5
names: Function
names: Similarity
messages: Belongs to the vitamin-B12 independent methionine synthase family.
messages: Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

931890:Ecym 4533
gene id: 931890:Ecym_4533
uniprot id: G8JU66
names: Similarity
messages: Belongs to the acetyltransferase family. ARD1 subfamily.

931890:Ecym 1444
gene id: 931890:Ecym_1444
uniprot id: G8JMF3
names: Subcellular Location Annotation
messages: Peroxisome membrane

931890:Ecym 5432
gene id: 931890:Ecym_5432
uniprot id: I6NDP3
names: Similarity
messages: Belongs to the glycosyl hydrolase 16 family.

931890:Ecym 4634
gene id: 931890:Ecym_4634
uniprot id: G8JSD5
names: Similarity
messages: In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily.

931890:Ecym 6134
gene id: 931890:Ecym_6134
uniprot id: G8JV46
names: Function
names: Similarity
messages: Belongs to the WD repeat EIF2A family.
messages: Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner.

931890:Ecym 8107
gene id: 931890:Ecym_8107
uniprot id: G8JX27
names: Similarity
messages: Belongs to the LST4 family.

931890:Ecym 3327
gene id: 931890:Ecym_3327
uniprot id: G8JRP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NFX1 family.
messages: Nucleus

931890:Ecym 4055
gene id: 931890:Ecym_4055
uniprot id: G8JSY3
names: Similarity
messages: Belongs to the universal ribosomal protein uL3 family.

931890:Ecym 4700
gene id: 931890:Ecym_4700
uniprot id: G8JSJ8
names: Similarity
messages: Belongs to the anthranilate synthase component I family.

931890:Ecym 6138
gene id: 931890:Ecym_6138
uniprot id: G8JV50
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ketol-acid reductoisomerase family.
messages: Binds 2 magnesium ions per subunit.
messages: Mitochondrion

931890:Ecym 3003
gene id: 931890:Ecym_3003
uniprot id: G8JQV3
names: Function
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
messages: Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle.

931890:Ecym 2717
gene id: 931890:Ecym_2717
uniprot id: G8JPF5
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 5486
gene id: 931890:Ecym_5486
uniprot id: I6NDT9
names: Function
names: Similarity
messages: Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily.
messages: Possesses 5'->3' exoribonuclease activity. May promote termination of transcription by RNA polymerase II.

931890:Ecym 3065
gene id: 931890:Ecym_3065
uniprot id: G8JR08
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.

931890:Ecym 3407
gene id: 931890:Ecym_3407
uniprot id: G8JRX4
names: Similarity
names: Subunit
messages: Belongs to the LDH/MDH superfamily. MDH type 1 family.
messages: Homodimer.

931890:Ecym 5199
gene id: 931890:Ecym_5199
uniprot id: I6ND28
names: Similarity
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.

931890:Ecym 6352
gene id: 931890:Ecym_6352
uniprot id: G8JUE8
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

931890:Ecym 4510
gene id: 931890:Ecym_4510
uniprot id: G8JU44
names: Function
names: Similarity
names: Subunit
messages: Belongs to the profilin family.
messages: Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
messages: Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

931890:Ecym 4151
gene id: 931890:Ecym_4151
uniprot id: G8JT75
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the kynureninase family.
messages: Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.
messages: Cytoplasm
messages: Homodimer.

931890:Ecym 4265
gene id: 931890:Ecym_4265
uniprot id: G8JTH6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
messages: Membrane

931890:Ecym 2295
gene id: 931890:Ecym_2295
uniprot id: G8JQ35
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

931890:Ecym 2565
gene id: 931890:Ecym_2565
uniprot id: G8JQC5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3-ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids.
messages: Endoplasmic reticulum membrane

931890:Ecym 7384
gene id: 931890:Ecym_7384
uniprot id: G8JWJ5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the 3-HAO family.
messages: Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
messages: Cytoplasm

931890:Ecym 4581
gene id: 931890:Ecym_4581
uniprot id: G8JS92
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the eukaryotic-type primase large subunit family.
messages: Binds 1 [4Fe-4S] cluster.
messages: DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

931890:Ecym 2583
gene id: 931890:Ecym_2583
uniprot id: G8JQG6
names: Function
names: Similarity
messages: Belongs to the SEC15 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

931890:Ecym 7026
gene id: 931890:Ecym_7026
uniprot id: G8JVL8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 7399
gene id: 931890:Ecym_7399
uniprot id: G8JWL0
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6378
gene id: 931890:Ecym_6378
uniprot id: G8JUH3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the THOC2 family.
messages: Nucleus

931890:Ecym 5572
gene id: 931890:Ecym_5572
uniprot id: I6NE18
names: Similarity
messages: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

931890:Ecym 4224
gene id: 931890:Ecym_4224
uniprot id: G8JTD8
names: Function
names: Similarity
messages: Belongs to the proline oxidase family.
messages: Converts proline to delta-1-pyrroline-5-carboxylate.

931890:Ecym 7390
gene id: 931890:Ecym_7390
uniprot id: G8JWK1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the UTP11 family.
messages: Component of the ribosomal small subunit (SSU) processome.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

931890:Ecym 1448
gene id: 931890:Ecym_1448
uniprot id: G8JMF7
names: Similarity
messages: Belongs to the cytidylyltransferase family.

931890:Ecym 6055
gene id: 931890:Ecym_6055
uniprot id: G8JUX9
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

931890:Ecym 5354
gene id: 931890:Ecym_5354
uniprot id: I6NDH0
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS7 family.

931890:Ecym 6154
gene id: 931890:Ecym_6154
uniprot id: G8JV65
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TIM21 family.
messages: Component of the TIM23 complex.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 7341
gene id: 931890:Ecym_7341
uniprot id: G8JWF6
names: Similarity
messages: Belongs to the cysteine synthase/cystathionine beta-synthase family.

931890:Ecym 2388
gene id: 931890:Ecym_2388
uniprot id: G8JNQ3
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 1165
gene id: 931890:Ecym_1165
uniprot id: G8JMV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DIF1/spd1 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 4323
gene id: 931890:Ecym_4323
uniprot id: G8JTN3
names: Similarity
names: Subcellular Location Annotation
messages: In the C-terminal section; belongs to the NAGSA dehydrogenase family.
messages: In the N-terminal section; belongs to the acetylglutamate kinase family.
messages: Mitochondrion

931890:Ecym 5218
gene id: 931890:Ecym_5218
uniprot id: I6ND45
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 3067
gene id: 931890:Ecym_3067
uniprot id: G8JR10
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2383
gene id: 931890:Ecym_2383
uniprot id: G8JNP8
names: Similarity
messages: Belongs to the APC5 family.

931890:Ecym 5237
gene id: 931890:Ecym_5237
uniprot id: I6ND62
names: Similarity
messages: Belongs to the actin family.

931890:Ecym 3153
gene id: 931890:Ecym_3153
uniprot id: G8JR87
names: Similarity
messages: Belongs to the actin family. ARP3 subfamily.

931890:Ecym 8110
gene id: 931890:Ecym_8110
uniprot id: G8JX30
names: Similarity
messages: Belongs to the PGA52 family.

931890:Ecym 5611
gene id: 931890:Ecym_5611
uniprot id: I6NE55
names: Cofactor
names: Function
names: Similarity
names: Subunit
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
messages: Heterodimer of an alpha and a beta subunit.

931890:Ecym 3144
gene id: 931890:Ecym_3144
uniprot id: G8JR78
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II.
messages: Cytoplasm
messages: Nucleus
messages: Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.

931890:Ecym 2736
gene id: 931890:Ecym_2736
uniprot id: G8JPG9
names: Similarity
messages: Belongs to the peptidase M28 family.

931890:Ecym 2725
gene id: 931890:Ecym_2725
uniprot id: G8JPG0
names: Function
names: Similarity
messages: Belongs to the diphthine synthase family.
messages: S-adenosyl-L-methionine-dependent methyltransferase that catalyzes four methylations of the modified target histidine residue in translation elongation factor 2 (EF-2), to form an intermediate called diphthine methyl ester. The four successive methylation reactions represent the second step of diphthamide biosynthesis.

931890:Ecym 3019
gene id: 931890:Ecym_3019
uniprot id: G8JQW7
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 7372
gene id: 931890:Ecym_7372
uniprot id: G8JWI3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

931890:Ecym 7415
gene id: 931890:Ecym_7415
uniprot id: G8JWM5
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate 1-epimerase family.
messages: Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P).

931890:Ecym 6192
gene id: 931890:Ecym_6192
uniprot id: G8JV96
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RFT1 family.
messages: Endoplasmic reticulum membrane
messages: May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane.
messages: Membrane

931890:Ecym 4790
gene id: 931890:Ecym_4790
uniprot id: G8JSS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF1 family.
messages: nucleolus

931890:Ecym 3176
gene id: 931890:Ecym_3176
uniprot id: G8JRA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Mediator complex subunit 20 family.
messages: Nucleus

931890:Ecym 7015
gene id: 931890:Ecym_7015
uniprot id: G8JVK7
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Nucleus

931890:Ecym 5470
gene id: 931890:Ecym_5470
uniprot id: I6NDS5
names: Similarity
messages: Belongs to the AFG1 ATPase family.

931890:Ecym 5444
gene id: 931890:Ecym_5444
uniprot id: I6NDQ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.
messages: cytoskeleton

931890:Ecym 1175
gene id: 931890:Ecym_1175
uniprot id: G8JMW1
names: Function
names: Similarity
messages: Belongs to the VPS28 family.
messages: Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process.

931890:Ecym 4320
gene id: 931890:Ecym_4320
uniprot id: G8JTN0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that mono- and dimethylates elongation factor 1-alpha at 'Lys-316'. May play a role in intracellular transport.

931890:Ecym 8338
gene id: 931890:Ecym_8338
uniprot id: G8JXP2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GrpE family.
messages: Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
messages: Mitochondrion matrix

931890:Ecym 5123
gene id: 931890:Ecym_5123
uniprot id: I6NCW0
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aconitase/IPM isomerase family.
messages: Binds 1 [4Fe-4S] cluster per subunit.
messages: Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis.
messages: Mitochondrion

931890:Ecym 3326
gene id: 931890:Ecym_3326
uniprot id: G8JRP7
names: Similarity
messages: Belongs to the isocitrate and isopropylmalate dehydrogenases family.

931890:Ecym 6491
gene id: 931890:Ecym_6491
uniprot id: G8JUS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG2 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Preautophagosomal structure membrane

931890:Ecym 5316
gene id: 931890:Ecym_5316
uniprot id: I6NDD5
names: Similarity
messages: Belongs to the MDM20/NAA25 family.

931890:Ecym 6047
gene id: 931890:Ecym_6047
uniprot id: G8JUX1
names: Similarity
messages: Belongs to the NADH dehydrogenase family.

931890:Ecym 5350
gene id: 931890:Ecym_5350
uniprot id: I6NDG7
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ING family.
messages: Component of an histone acetyltransferase complex.
messages: Component of an histone acetyltransferase complex. Interacts with H3K4me3 and to a lesser extent with H3K4me2.
messages: Nucleus
messages: The PHD-type zinc finger mediates the binding to H3K4me3.

931890:Ecym 5010
gene id: 931890:Ecym_5010
uniprot id: I6NCM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the rad1 family.
messages: Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes.
messages: Nucleus

931890:Ecym 5646
gene id: 931890:Ecym_5646
uniprot id: I6NE89
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

931890:Ecym 5131
gene id: 931890:Ecym_5131
uniprot id: I6NCW7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8207
gene id: 931890:Ecym_8207
uniprot id: G8JXB8
names: Similarity
messages: Belongs to the Nudix hydrolase family. DCP2 subfamily.

931890:Ecym 6373
gene id: 931890:Ecym_6373
uniprot id: G8JUG8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF7 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

931890:Ecym 7325
gene id: 931890:Ecym_7325
uniprot id: G8JWE4
names: Similarity
messages: Belongs to the tRNA pseudouridine synthase TruA family.

931890:Ecym 3371
gene id: 931890:Ecym_3371
uniprot id: G8JRT9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

931890:Ecym 6032
gene id: 931890:Ecym_6032
uniprot id: G8JUV8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD1 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 1394
gene id: 931890:Ecym_1394
uniprot id: G8JM53
names: Similarity
messages: Belongs to the RRM CWC2 family.

931890:Ecym 3314
gene id: 931890:Ecym_3314
uniprot id: G8JRN6
names: Similarity
messages: Belongs to the glycosyl hydrolase 15 family.

931890:Ecym 7100
gene id: 931890:Ecym_7100
uniprot id: G8JVT7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIA subunit 1 family.
messages: Nucleus

931890:Ecym 3088
gene id: 931890:Ecym_3088
uniprot id: G8JR29
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

931890:Ecym 5343
gene id: 931890:Ecym_5343
uniprot id: I6NDG0
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 1443
gene id: 931890:Ecym_1443
uniprot id: G8JMF2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Associated with the spliceosome.
messages: Belongs to the CWC24 family.
messages: Involved in pre-mRNA splicing.
messages: Nucleus

931890:Ecym 2799
gene id: 931890:Ecym_2799
uniprot id: G8JQD3
names: Similarity
messages: Belongs to the iron/manganese superoxide dismutase family.

931890:Ecym 4499
gene id: 931890:Ecym_4499
uniprot id: G8JU35
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
messages: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as AHP1. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
messages: Belongs to the URM1 family.
messages: C-terminal thiocarboxylation occurs in 2 steps, it is first acyl-adenylated (-COAMP) via the hesA/moeB/thiF part of UBA4, then thiocarboxylated (-COSH) via the rhodanese domain of UBA4.
messages: Cytoplasm

931890:Ecym 3612
gene id: 931890:Ecym_3612
uniprot id: G8JQT9
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5544
gene id: 931890:Ecym_5544
uniprot id: I6NDZ2
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 5527
gene id: 931890:Ecym_5527
uniprot id: I6NDX6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 4529
gene id: 931890:Ecym_4529
uniprot id: G8JU63
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL27 family.

931890:Ecym 5396
gene id: 931890:Ecym_5396
uniprot id: I6NDK9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1268
gene id: 931890:Ecym_1268
uniprot id: G8JN45
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3604
gene id: 931890:Ecym_3604
uniprot id: G8JQT3
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2042
gene id: 931890:Ecym_2042
uniprot id: G8JNZ9
names: Similarity
messages: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. GSK-3 subfamily.

931890:Ecym 4604
gene id: 931890:Ecym_4604
uniprot id: G8JSB2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.
messages: Component of a multi-subunit COQ enzyme complex, composed of at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9.
messages: Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
messages: Mitochondrion inner membrane

931890:Ecym 1222
gene id: 931890:Ecym_1222
uniprot id: G8JN05
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4319
gene id: 931890:Ecym_4319
uniprot id: G8JTM9
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIS1 family.
messages: Has a role in mitochondrial fission.
messages: Membrane
messages: Mitochondrion outer membrane
messages: The C-terminus is required for mitochondrial localization, while the N-terminus is necessary for mitochondrial fission.

931890:Ecym 8152
gene id: 931890:Ecym_8152
uniprot id: G8JX66
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 6203
gene id: 931890:Ecym_6203
uniprot id: G8JVA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

931890:Ecym 2628
gene id: 931890:Ecym_2628
uniprot id: G8JQK8
names: Similarity
names: Subunit
messages: Belongs to the SIL1 family.
messages: Interacts with KAR2.

931890:Ecym 1256
gene id: 931890:Ecym_1256
uniprot id: G8JN34
names: Similarity
messages: Belongs to the universal ribosomal protein uS5 family.

931890:Ecym 3358
gene id: 931890:Ecym_3358
uniprot id: G8JRS7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

931890:Ecym 2591
gene id: 931890:Ecym_2591
uniprot id: G8JQH3
names: Similarity
messages: Belongs to the APC10 family.

931890:Ecym 7003
gene id: 931890:Ecym_7003
uniprot id: G8JVJ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ESF2/ABP1 family.
messages: nucleolus

931890:Ecym 5008
gene id: 931890:Ecym_5008
uniprot id: I6NCL9
names: Function
names: Similarity
messages: Belongs to the Rab GDI family.
messages: Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.

931890:Ecym 2201
gene id: 931890:Ecym_2201
uniprot id: G8JP45
names: Subcellular Location Annotation
messages: Cell surface

931890:Ecym 2614
gene id: 931890:Ecym_2614
uniprot id: G8JQJ4
names: Subcellular Location Annotation
names: Subunit
messages: Nucleus
messages: The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel.

931890:Ecym 4273
gene id: 931890:Ecym_4273
uniprot id: G8JTI4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the midasin family.
messages: Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 5567
gene id: 931890:Ecym_5567
uniprot id: I6NE13
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.
messages: Mediates the uptake of pyruvate into mitochondria.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 1056
gene id: 931890:Ecym_1056
uniprot id: G8JMA5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 5660
gene id: 931890:Ecym_5660
uniprot id: I6NEA1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4167
gene id: 931890:Ecym_4167
uniprot id: G8JT91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

931890:Ecym 4406
gene id: 931890:Ecym_4406
uniprot id: G8JTV6
names: Similarity
messages: Belongs to the RRP15 family.

931890:Ecym 7151
gene id: 931890:Ecym_7151
uniprot id: G8JVY5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the GatB/GatE family. GatB subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

931890:Ecym 4486
gene id: 931890:Ecym_4486
uniprot id: G8JU22
names: Similarity
messages: Belongs to the synaptojanin family.
messages: In the central section; belongs to the inositol 1,4,5-trisphosphate 5-phosphatase family.

931890:Ecym 1010
gene id: 931890:Ecym_1010
uniprot id: G8JM09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the MICOS complex subunit Mic10 family.
messages: Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
messages: Component of the mitochondrial contact site and cristae organizing system (MICOS) complex.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8008
gene id: 931890:Ecym_8008
uniprot id: G8JXX8
names: Similarity
messages: Belongs to the TCF25 family.

931890:Ecym 4593
gene id: 931890:Ecym_4593
uniprot id: G8JSA3
names: Similarity
messages: Belongs to the NifU family.

931890:Ecym 1136
gene id: 931890:Ecym_1136
uniprot id: G8JMN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HMG-CoA reductase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 6365
gene id: 931890:Ecym_6365
uniprot id: G8JUG1
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 3390
gene id: 931890:Ecym_3390
uniprot id: G8JRV8
names: Similarity
messages: Belongs to the DNA2/NAM7 helicase family.

931890:Ecym 2131
gene id: 931890:Ecym_2131
uniprot id: G8JNG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VTI1 family.
messages: Membrane

931890:Ecym 4748
gene id: 931890:Ecym_4748
uniprot id: G8JSP1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acid sphingomyelinase family.
messages: Secreted

931890:Ecym 1093
gene id: 931890:Ecym_1093
uniprot id: G8JME0
names: Similarity
messages: Belongs to the zinc-containing alcohol dehydrogenase family.

931890:Ecym 8171
gene id: 931890:Ecym_8171
uniprot id: G8JX83
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ATPase e subunit family.
messages: F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
messages: Mitochondrion inner membrane

931890:Ecym 4768
gene id: 931890:Ecym_4768
uniprot id: G8JSQ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
messages: Belongs to the amidase family. GatA subfamily.
messages: Mitochondrion
messages: Subunit of the heterotrimeric GatFAB amidotransferase (AdT) complex, composed of A, B and F subunits.

931890:Ecym 1017
gene id: 931890:Ecym_1017
uniprot id: G8JM16
names: Similarity
messages: Belongs to the MT-A70-like family.

931890:Ecym 2551
gene id: 931890:Ecym_2551
uniprot id: G8JQB3
names: Similarity
messages: Belongs to the alkaline phosphatase family.

931890:Ecym 3161
gene id: 931890:Ecym_3161
uniprot id: G8JR95
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm

931890:Ecym 8364
gene id: 931890:Ecym_8364
uniprot id: G8JXR3
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-6 family.
messages: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export.
messages: Cytoplasm
messages: Monomer. Associates with the 60S ribosomal subunit.
messages: Phosphorylation at Ser-174 and Ser-175 promotes nuclear export.
messages: nucleolus

931890:Ecym 3204
gene id: 931890:Ecym_3204
uniprot id: G8JRD4
names: Function
messages: Cleaves A-5'-PPP-5'A to yield AMP and ADP. Can cleave all dinucleoside polyphosphates, provided the phosphate chain contains at least 3 phosphates and that 1 of the 2 bases composing the nucleotide is a purine. Is most effective on dinucleoside triphosphates. Negatively regulates intracellular dinucleoside polyphosphate levels, which elevate following heat shock.

931890:Ecym 4094
gene id: 931890:Ecym_4094
uniprot id: G8JT20
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 13 family.
messages: Component of the SRB8-11 complex, which itself associates with the Mediator complex.
messages: Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
messages: Nucleus

931890:Ecym 1058
gene id: 931890:Ecym_1058
uniprot id: G8JMA7
names: Similarity
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. NIM1 subfamily.

931890:Ecym 5665
gene id: 931890:Ecym_5665
uniprot id: I6NEA6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 5191
gene id: 931890:Ecym_5191
uniprot id: I6ND21
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM23 complex, at least composed of TIM23, TIM17, TIM50 and TIM21.
messages: Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5327
gene id: 931890:Ecym_5327
uniprot id: I6NDE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic release factor 1 family.
messages: Cytoplasm

931890:Ecym 7113
gene id: 931890:Ecym_7113
uniprot id: G8JVV0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFIIF alpha subunit family.
messages: Nucleus
messages: TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation.

931890:Ecym 1117
gene id: 931890:Ecym_1117
uniprot id: G8JML6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5496
gene id: 931890:Ecym_5496
uniprot id: I6NDU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.
messages: Membrane

931890:Ecym 7400
gene id: 931890:Ecym_7400
uniprot id: G8JWL1
names: Similarity
messages: In the C-terminal section; belongs to the peptidase M41 family.
messages: In the N-terminal section; belongs to the AAA ATPase family.

931890:Ecym 1020
gene id: 931890:Ecym_1020
uniprot id: G8JM19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGX family.
messages: Endoplasmic reticulum membrane
messages: Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.

931890:Ecym 1214
gene id: 931890:Ecym_1214
uniprot id: G8JMZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acyl-CoA oxidase family.
messages: Peroxisome

931890:Ecym 5587
gene id: 931890:Ecym_5587
uniprot id: I6NE33
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

931890:Ecym 8024
gene id: 931890:Ecym_8024
uniprot id: G8JWU6
names: Similarity
messages: Belongs to the AIM9 family.

931890:Ecym 5501
gene id: 931890:Ecym_5501
uniprot id: I6NDV2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the WD repeat CIA1 family.
messages: Cytoplasm
messages: Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins.
messages: Interacts with NAR1.
messages: Nucleus

931890:Ecym 6018
gene id: 931890:Ecym_6018
uniprot id: G8JUU7
names: Similarity
messages: Belongs to the adaptor complexes small subunit family.

931890:Ecym 4578
gene id: 931890:Ecym_4578
uniprot id: G8JS89
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 5043
gene id: 931890:Ecym_5043
uniprot id: I6NCP6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA43 RNA polymerase subunit family.
messages: nucleolus

931890:Ecym 8151
gene id: 931890:Ecym_8151
uniprot id: G8JX65
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 5355
gene id: 931890:Ecym_5355
uniprot id: I6NDH1
names: Similarity
messages: Belongs to the ribose 5-phosphate isomerase family.

931890:Ecym 2807
gene id: 931890:Ecym_2807
uniprot id: G8JQE1
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.
messages: Binds 1 zinc ion per subunit.
messages: Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX.

931890:Ecym 1259
gene id: 931890:Ecym_1259
uniprot id: G8JN37
names: Similarity
messages: Belongs to the MAPRE family.

931890:Ecym 4482
gene id: 931890:Ecym_4482
uniprot id: G8JU19
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP16 family.
messages: Involved in the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

931890:Ecym 1069
gene id: 931890:Ecym_1069
uniprot id: G8JMB8
names: Similarity
messages: Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase NEP1 family.

931890:Ecym 2028
gene id: 931890:Ecym_2028
uniprot id: G8JNY7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 7 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 6360
gene id: 931890:Ecym_6360
uniprot id: G8JUF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ThrE exporter (TC 2.A.79) family.
messages: Membrane

931890:Ecym 6207
gene id: 931890:Ecym_6207
uniprot id: G8JVB1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PER33/POM33 family.
messages: Membrane

931890:Ecym 7179
gene id: 931890:Ecym_7179
uniprot id: G8JW12
names: Subcellular Location Annotation
messages: Nucleus
messages: kinetochore

931890:Ecym 5037
gene id: 931890:Ecym_5037
uniprot id: I6NCP3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 6413
gene id: 931890:Ecym_6413
uniprot id: G8JUK5
names: Cofactor
names: Function
names: PTM
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily.
messages: Binds 1 pyruvoyl group covalently per subunit.
messages: Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine.
messages: Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.
messages: Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The autoendoproteolytic cleavage occurs by a canonical serine protease mechanism, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain. During this reaction, the Ser that is part of the protease active site of the proenzyme becomes the pyruvoyl prosthetic group, which constitutes an essential element of the active site of the mature decarboxylase.
messages: Mitochondrion inner membrane

931890:Ecym 3466
gene id: 931890:Ecym_3466
uniprot id: G8JS30
names: Function
messages: Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER.

931890:Ecym 2202
gene id: 931890:Ecym_2202
uniprot id: G8JP46
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 7309
gene id: 931890:Ecym_7309
uniprot id: G8JWD1
names: Cofactor
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 7387
gene id: 931890:Ecym_7387
uniprot id: G8JWJ8
names: Similarity
messages: Belongs to the HAD-like hydrolase superfamily. SerB family.

931890:Ecym 7109
gene id: 931890:Ecym_7109
uniprot id: G8JVU6
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4130
gene id: 931890:Ecym_4130
uniprot id: G8JT56
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H2A family.
messages: Chromosome
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 6024
gene id: 931890:Ecym_6024
uniprot id: G8JUV0
names: Similarity
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.

931890:Ecym 2764
gene id: 931890:Ecym_2764
uniprot id: G8JQ00
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC3 family.
messages: Component of the Arp2/3 complex.
messages: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

931890:Ecym 8419
gene id: 931890:Ecym_8419
uniprot id: G8JXW4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2610
gene id: 931890:Ecym_2610
uniprot id: G8JQJ0
names: Similarity
messages: Belongs to the eIF-2B alpha/beta/delta subunits family.

931890:Ecym 6458
gene id: 931890:Ecym_6458
uniprot id: G8JUP9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RRG9 family.
messages: Mitochondrion
messages: Required for respiratory activity and maintenance and expression of the mitochondrial genome.

931890:Ecym 8209
gene id: 931890:Ecym_8209
uniprot id: G8JXC0
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

931890:Ecym 3072
gene id: 931890:Ecym_3072
uniprot id: G8JR15
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DUO1 family.
messages: Nucleus
messages: kinetochore

931890:Ecym 3350
gene id: 931890:Ecym_3350
uniprot id: G8JRR9
names: Similarity
messages: Belongs to the protein prenyltransferase subunit beta family.

931890:Ecym 8278
gene id: 931890:Ecym_8278
uniprot id: G8JXI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the OST1 family.
messages: Component of the oligosaccharyltransferase (OST) complex.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity.

931890:Ecym 5108
gene id: 931890:Ecym_5108
uniprot id: I6NCU8
names: Function
names: Similarity
names: Subunit
messages: Belongs to the 6-phosphogluconate dehydrogenase family.
messages: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
messages: Homodimer.

931890:Ecym 7096
gene id: 931890:Ecym_7096
uniprot id: G8JVT3
names: Cofactor
names: Similarity
messages: Belongs to the arginase family.
messages: Binds 2 manganese ions per subunit.

931890:Ecym 3255
gene id: 931890:Ecym_3255
uniprot id: G8JRH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BCAP29/BCAP31 family.
messages: Endoplasmic reticulum membrane
messages: May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi.
messages: Membrane

931890:Ecym 2697
gene id: 931890:Ecym_2697
uniprot id: G8JPD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

931890:Ecym 5534
gene id: 931890:Ecym_5534
uniprot id: I6NDY2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS41 family.
messages: Required for vacuolar assembly and vacuolar traffic.
messages: Vacuole

931890:Ecym 1473
gene id: 931890:Ecym_1473
uniprot id: G8JMI2
names: Similarity
messages: Belongs to the glycosyl hydrolase 32 family.

931890:Ecym 8162
gene id: 931890:Ecym_8162
uniprot id: G8JX75
names: Function
names: Similarity
names: Subunit
messages: Belongs to the SKP1 family.
messages: Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes.
messages: Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins.

931890:Ecym 6072
gene id: 931890:Ecym_6072
uniprot id: G8JUZ1
names: Similarity
messages: Belongs to the DNA mismatch repair MutL/HexB family.

931890:Ecym 3420
gene id: 931890:Ecym_3420
uniprot id: G8JRY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 3496
gene id: 931890:Ecym_3496
uniprot id: G8JS58
names: Subcellular Location Annotation
messages: Membrane
messages: Vacuole membrane

931890:Ecym 3605
gene id: 931890:Ecym_3605
uniprot id: G8JQT4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8314
gene id: 931890:Ecym_8314
uniprot id: G8JXL8
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

931890:Ecym 5022
gene id: 931890:Ecym_5022
uniprot id: I6NCN1
names: Similarity
messages: Belongs to the BolA/IbaG family.

931890:Ecym 1050
gene id: 931890:Ecym_1050
uniprot id: G8JM99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the complex I LYR family. SDHAF3 subfamily.
messages: Interacts with the iron-sulfur protein subunit within the SDH catalytic dimer.
messages: Mitochondrion matrix
messages: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Promotes maturation of the iron-sulfur protein subunit of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants. May act together with SDHAF1.

931890:Ecym 6291
gene id: 931890:Ecym_6291
uniprot id: G8JVJ2
names: Similarity
messages: Belongs to the SDHAF4 family.

931890:Ecym 4491
gene id: 931890:Ecym_4491
uniprot id: G8JU27
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.

931890:Ecym 7167
gene id: 931890:Ecym_7167
uniprot id: G8JW00
names: Function
names: Similarity
messages: Belongs to the CTP synthase family.
messages: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.

931890:Ecym 3595
gene id: 931890:Ecym_3595
uniprot id: G8JQS6
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1454
gene id: 931890:Ecym_1454
uniprot id: G8JMG3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP Sm proteins family.
messages: Nucleus

931890:Ecym 3130
gene id: 931890:Ecym_3130
uniprot id: G8JR65
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. RHD3 subfamily.
messages: Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization.
messages: Endoplasmic reticulum membrane

931890:Ecym 2089
gene id: 931890:Ecym_2089
uniprot id: G8JPJ3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 48 family.
messages: Membrane

931890:Ecym 8359
gene id: 931890:Ecym_8359
uniprot id: G8JXQ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase g subunit family.
messages: Membrane

931890:Ecym 5256
gene id: 931890:Ecym_5256
uniprot id: I6ND80
names: Similarity
names: Subunit
messages: Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family.
messages: Homotetramer.

931890:Ecym 1363
gene id: 931890:Ecym_1363
uniprot id: G8JND2
names: Similarity
messages: Belongs to the OMP decarboxylase family.

931890:Ecym 1161
gene id: 931890:Ecym_1161
uniprot id: G8JMU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the universal ribosomal protein uL29 family.
messages: Mitochondrion

931890:Ecym 6238
gene id: 931890:Ecym_6238
uniprot id: G8JVE1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 1163
gene id: 931890:Ecym_1163
uniprot id: G8JMU9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NTE family.
messages: Endoplasmic reticulum membrane
messages: Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis.

931890:Ecym 6336
gene id: 931890:Ecym_6336
uniprot id: G8JUD2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO70 family.
messages: Bud
messages: Bud neck
messages: Involved in the secretory pathway as part of the exocyst complex which tethers secretory vesicles to the sites of exocytosis. Also plays a role in the assembly of the exocyst.

931890:Ecym 2068
gene id: 931890:Ecym_2068
uniprot id: G8JPH6
names: Similarity
messages: Belongs to the exportin family.

931890:Ecym 1272
gene id: 931890:Ecym_1272
uniprot id: G8JN49
names: Function
names: Similarity
messages: Belongs to the peptidase T1A family.
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 3549
gene id: 931890:Ecym_3549
uniprot id: G8JQN9
names: Similarity
messages: Belongs to the SF3A3 family.

931890:Ecym 1347
gene id: 931890:Ecym_1347
uniprot id: G8JNB7
names: Similarity
messages: Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

931890:Ecym 4661
gene id: 931890:Ecym_4661
uniprot id: G8JSG0
names: Similarity
names: Subunit
messages: Belongs to the glutamine synthetase family.
messages: Homooctamer.

931890:Ecym 8080
gene id: 931890:Ecym_8080
uniprot id: G8JX01
names: Similarity
messages: Belongs to the SAS10 family.

931890:Ecym 5052
gene id: 931890:Ecym_5052
uniprot id: I6NCQ1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-Y family.
messages: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.
messages: Nucleus

931890:Ecym 2782
gene id: 931890:Ecym_2782
uniprot id: G8JQ17
names: Function
names: Similarity
messages: Belongs to the transferase hexapeptide repeat family.
messages: Involved in cell wall synthesis where it is required for glycosylation. Involved in cell cycle progression through cell-size checkpoint.

931890:Ecym 8400
gene id: 931890:Ecym_8400
uniprot id: G8JXU6
names: Subcellular Location Annotation
messages: Cytoplasm
messages: Membrane
messages: Preautophagosomal structure membrane

931890:Ecym 2645
gene id: 931890:Ecym_2645
uniprot id: G8JNT2
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8148
gene id: 931890:Ecym_8148
uniprot id: G8JX62
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5640
gene id: 931890:Ecym_5640
uniprot id: I6NE84
names: Caution
names: Domain
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the protein kinase superfamily. PAN3 family.
messages: Contains a pseudokinase domain. The protein kinase domain is predicted to be catalytically inactive because some of the residues important for catalytic activity are substituted and it lacks the equivalent of the binding site for a peptide substrate. However, it has retained an ATP-binding site and ATP-binding is required for mRNA degradation, stimulating the activity of the PAN2 nuclease in vitro. The nucleotide-binding site is juxtaposed to the RNase active site of PAN2 in the complex and may actually bind nucleosides of a poly(A) RNA rather than ATP, feeding the poly(A)-tail to the active site of the deadenylase and thus increasing the efficiency with which this distributive enzyme degrades oligo(A) RNAs.
messages: Cytoplasm
messages: Homodimer. Forms a heterotrimer with a catalytic subunit PAN2 to form the poly(A)-nuclease (PAN) deadenylation complex. Interacts (via PAM-2 motif) with poly(A)-binding protein PAB1 (via PABC domain), conferring substrate specificity of the enzyme complex.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Regulatory subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein PAB1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequent 5'-3' exonucleolytic degradation by XRN1. May also be involved in post-transcriptional maturation of mRNA poly(A) tails. PAN3 acts as a positive regulator for PAN activity, recruiting the catalytic subunit PAN2 to mRNA via its interaction with RNA and with PAB1.
messages: The N-terminal zinc finger binds to poly(A) RNA.
messages: The pseudokinase domain, the coiled-coil (CC), and C-terminal knob domain (CK) form a structural unit (PKC) that forms an extensive high-affinity interaction surface for PAN2.

931890:Ecym 4579
gene id: 931890:Ecym_4579
uniprot id: G8JS90
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2318
gene id: 931890:Ecym_2318
uniprot id: G8JQ58
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the XPF family.
messages: Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single-end invasion (SEI).
messages: Interacts with EME1.
messages: Nucleus

931890:Ecym 7436
gene id: 931890:Ecym_7436
uniprot id: G8JWP2
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL19 family.

931890:Ecym 8329
gene id: 931890:Ecym_8329
uniprot id: G8JXN3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5028
gene id: 931890:Ecym_5028
uniprot id: I6NCN6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4190
gene id: 931890:Ecym_4190
uniprot id: G8JTB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CybS family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 6364
gene id: 931890:Ecym_6364
uniprot id: G8JUG0
names: Similarity
messages: Belongs to the phospholipase D family.

931890:Ecym 6009
gene id: 931890:Ecym_6009
uniprot id: G8JUT8
names: Similarity
messages: Belongs to the cyclic nucleotide phosphodiesterase class-II family.

931890:Ecym 2627
gene id: 931890:Ecym_2627
uniprot id: G8JQK7
names: Similarity
messages: Belongs to the OPI10 family.

931890:Ecym 5260
gene id: 931890:Ecym_5260
uniprot id: I6ND84
names: Similarity
messages: Belongs to the methyltransferase superfamily. Fibrillarin family.

931890:Ecym 3406
gene id: 931890:Ecym_3406
uniprot id: G8JRX3
names: Similarity
messages: Belongs to the sulfiredoxin family.

931890:Ecym 2321
gene id: 931890:Ecym_2321
uniprot id: G8JQ61
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.
messages: Membrane

931890:Ecym 8153
gene id: 931890:Ecym_8153
uniprot id: G8JX67
names: Similarity
messages: Belongs to the prefoldin subunit alpha family.

931890:Ecym 2770
gene id: 931890:Ecym_2770
uniprot id: G8JQ06
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the KRE9/KNH1 family.
messages: Involved in cell wall beta(1->6) glucan synthesis.
messages: cell wall

931890:Ecym 3488
gene id: 931890:Ecym_3488
uniprot id: G8JS52
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 2098
gene id: 931890:Ecym_2098
uniprot id: G8JPK2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4462
gene id: 931890:Ecym_4462
uniprot id: G8JU01
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the acireductone dioxygenase (ARD) family.
messages: Binds either 1 Fe or Ni cation per monomer. Iron-binding promotes an acireductone dioxygenase reaction producing 2-keto-4-methylthiobutyrate, while nickel-binding promotes an acireductone dioxygenase reaction producing 3-(methylsulfanyl)propanoate.
messages: Catalyzes 2 different reactions between oxygen and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4-methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 6488
gene id: 931890:Ecym_6488
uniprot id: G8JUS6
names: Similarity
messages: Belongs to the NARF family.

931890:Ecym 8271
gene id: 931890:Ecym_8271
uniprot id: G8JXH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MPP10 family.
messages: Involved in nucleolar processing of pre-18S ribosomal RNA.
messages: nucleolus

931890:Ecym 5287
gene id: 931890:Ecym_5287
uniprot id: I6NDA7
names: Similarity
messages: Belongs to the PP2C family.

931890:Ecym 5118
gene id: 931890:Ecym_5118
uniprot id: I6NCV6
names: Similarity
messages: Belongs to the universal ribosomal protein uL5 family.

931890:Ecym 2205
gene id: 931890:Ecym_2205
uniprot id: G8JP49
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
messages: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
messages: nucleolus

931890:Ecym 2271
gene id: 931890:Ecym_2271
uniprot id: G8JPR2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3361
gene id: 931890:Ecym_3361
uniprot id: G8JRS9
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 8105
gene id: 931890:Ecym_8105
uniprot id: G8JX25
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2695
gene id: 931890:Ecym_2695
uniprot id: G8JPD7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 4738
gene id: 931890:Ecym_4738
uniprot id: G8JSN3
names: Cofactor
names: Similarity
messages: Belongs to the peptidase M1 family.
messages: Binds 1 zinc ion per subunit.

931890:Ecym 4543
gene id: 931890:Ecym_4543
uniprot id: G8JU75
names: Similarity
messages: Belongs to the IUNH family.

931890:Ecym 8231
gene id: 931890:Ecym_8231
uniprot id: G8JXE2
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.

931890:Ecym 3101
gene id: 931890:Ecym_3101
uniprot id: G8JR40
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. LepA subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
messages: Mitochondrion inner membrane
messages: Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.

931890:Ecym 5657
gene id: 931890:Ecym_5657
uniprot id: I6NE98
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 17 family.
messages: cell wall

931890:Ecym 2142
gene id: 931890:Ecym_2142
uniprot id: G8JNH8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4662
gene id: 931890:Ecym_4662
uniprot id: G8JSG1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase H subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme made up of two complexes: the ATP-hydrolytic V1 complex and the proton translocation V0 complex.

931890:Ecym 2349
gene id: 931890:Ecym_2349
uniprot id: G8JNL5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RPAP2 family.
messages: Nucleus
messages: Putative RNA polymerase II subunit B1 C-terminal domain (CTD) phosphatase involved in RNA polymerase II transcription regulation.

931890:Ecym 2643
gene id: 931890:Ecym_2643
uniprot id: G8JNT0
names: Cofactor
names: Similarity
messages: Belongs to the eukaryotic GSH synthase family.
messages: Binds 1 Mg(2+) ion per subunit.

931890:Ecym 7274
gene id: 931890:Ecym_7274
uniprot id: G8JWA1
names: Similarity
messages: Belongs to the TACO1 family.

931890:Ecym 5536
gene id: 931890:Ecym_5536
uniprot id: I6NDY4
names: Similarity
messages: Belongs to the COG3 family.

931890:Ecym 2417
gene id: 931890:Ecym_2417
uniprot id: G8JP91
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS25 family.

931890:Ecym 7017
gene id: 931890:Ecym_7017
uniprot id: G8JVK9
names: Function
names: Similarity
messages: Belongs to the acyl carrier protein (ACP) family.
messages: Carrier of the growing fatty acid chain in fatty acid biosynthesis.

931890:Ecym 2189
gene id: 931890:Ecym_2189
uniprot id: G8JP33
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS29 family.
messages: Mitochondrion

931890:Ecym 7132
gene id: 931890:Ecym_7132
uniprot id: G8JVW7
names: Similarity
messages: Belongs to the bacterial ribosomal protein bS21 family.

931890:Ecym 1392
gene id: 931890:Ecym_1392
uniprot id: G8JM51
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

931890:Ecym 5308
gene id: 931890:Ecym_5308
uniprot id: G8JRR0
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the histone H4 family.
messages: Chromosome
messages: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
messages: Nucleus
messages: The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.

931890:Ecym 2633
gene id: 931890:Ecym_2633
uniprot id: G8JNS0
names: Function
names: Similarity
messages: Belongs to the RRM RBM34 family.
messages: Involved in pre-25S rRNA processing.

931890:Ecym 5467
gene id: 931890:Ecym_5467
uniprot id: I6NDS3
names: Similarity
messages: Belongs to the universal ribosomal protein uL2 family.

931890:Ecym 2609
gene id: 931890:Ecym_2609
uniprot id: G8JQI9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL43 family.
messages: Mitochondrion

931890:Ecym 7136
gene id: 931890:Ecym_7136
uniprot id: G8JVX0
names: Similarity
messages: Belongs to the universal ribosomal protein uL14 family.

931890:Ecym 4743
gene id: 931890:Ecym_4743
uniprot id: G8JSN8
names: Similarity
messages: Belongs to the RMD1/sif2 family.

931890:Ecym 2479
gene id: 931890:Ecym_2479
uniprot id: G8JPU4
names: Cofactor
names: Similarity
messages: Belongs to the TPP enzyme family.
messages: Binds 1 Mg(2+) per subunit.

931890:Ecym 4134
gene id: 931890:Ecym_4134
uniprot id: G8JT60
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 3609
gene id: 931890:Ecym_3609
uniprot id: G8JQT7
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.
messages: Cytoplasm
messages: Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP.
messages: Monomer.

931890:Ecym 1134
gene id: 931890:Ecym_1134
uniprot id: G8JMN1
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the TRAPP small subunits family.
messages: Endoplasmic reticulum
messages: Part of the multisubunit transport protein particle (TRAPP) complex.
messages: cis-Golgi network

931890:Ecym 5205
gene id: 931890:Ecym_5205
uniprot id: I6ND32
names: Similarity
messages: Belongs to the AIM23 family.

931890:Ecym 3461
gene id: 931890:Ecym_3461
uniprot id: G8JS26
names: Similarity
messages: Belongs to the Nudix hydrolase family.

931890:Ecym 4216
gene id: 931890:Ecym_4216
uniprot id: G8JTD0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the snRNP core protein family.
messages: Nucleus
messages: cytosol

931890:Ecym 5128
gene id: 931890:Ecym_5128
uniprot id: I6NCW5
names: Similarity
messages: Belongs to the glycosyl hydrolase 5 (cellulase A) family.

931890:Ecym 7061
gene id: 931890:Ecym_7061
uniprot id: G8JVP9
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS6 family.

931890:Ecym 1108
gene id: 931890:Ecym_1108
uniprot id: G8JMK8
names: Similarity
messages: Belongs to the SMC family. RAD50 subfamily.

931890:Ecym 4068
gene id: 931890:Ecym_4068
uniprot id: G8JSZ5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the sorting nexin family.
messages: Endosome membrane
messages: Membrane

931890:Ecym 8199
gene id: 931890:Ecym_8199
uniprot id: G8JXB0
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.
messages: Chromosome
messages: Component of the COMPASS (Set1C) complex.
messages: Nucleus

931890:Ecym 8091
gene id: 931890:Ecym_8091
uniprot id: G8JX12
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8020
gene id: 931890:Ecym_8020
uniprot id: G8JWU2
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 4621
gene id: 931890:Ecym_4621
uniprot id: G8JSC8
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7172
gene id: 931890:Ecym_7172
uniprot id: G8JW05
names: Similarity
messages: Belongs to the peptidase M20A family.

931890:Ecym 2448
gene id: 931890:Ecym_2448
uniprot id: G8JPB9
names: Similarity
messages: Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.

931890:Ecym 5289
gene id: 931890:Ecym_5289
uniprot id: I6NDA9
names: Similarity
messages: Belongs to the ATPase epsilon chain family.

931890:Ecym 2621
gene id: 931890:Ecym_2621
uniprot id: G8JQK1
names: Function
names: Similarity
messages: Belongs to the phosphatase 2A regulatory subunit.
messages: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.

931890:Ecym 1525
gene id: 931890:Ecym_1525
uniprot id: G8JMT1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily.
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
messages: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.
messages: Mitochondrion

931890:Ecym 5178
gene id: 931890:Ecym_5178
uniprot id: I6ND09
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S64 family.
messages: Cell membrane
messages: Component of the plasma membrane SPS (SSY1-PTR3-SSY5) amino acid sensor complex.
messages: Protease component of the SPS-sensor system, which regulates the expression of several amino acid-metabolizing enzymes and amino acid- and peptide-permeases in response to extracellular amino acid levels by controlling the activity of two transcription factors, STP1 and STP2. Catalyzes the activation of these transcription factors, which are synthesized as latent cytoplasmic precursors, by proteolytic removal of an N-terminal inhibitory domain containing cytoplasmic retention motifs. SSY5 binds as an inactive protease complex to STP1. In response to extracellular amino acids and dependent on the other SPS-sensor components, the inhibitory propeptide is induced to dissociate, and thereby enables the catalytic domain to process STP1.

931890:Ecym 2625
gene id: 931890:Ecym_2625
uniprot id: G8JQK5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SMC family. SMC5 subfamily.
messages: Nucleus

931890:Ecym 2211
gene id: 931890:Ecym_2211
uniprot id: G8JP55
names: Similarity
messages: Belongs to the universal ribosomal protein uL30 family.

931890:Ecym 6127
gene id: 931890:Ecym_6127
uniprot id: G8JV40
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5463
gene id: 931890:Ecym_5463
uniprot id: I6NDS0
names: Similarity
messages: Belongs to the carnitine/choline acetyltransferase family.

931890:Ecym 2404
gene id: 931890:Ecym_2404
uniprot id: G8JP79
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: A monovalent cation.
messages: Belongs to the folylpolyglutamate synthase family.
messages: Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis. Required for methionine synthesis and maintenance of intact mitochondrial DNA. Involved in telomere maintenance.
messages: Membrane
messages: Mitochondrion inner membrane
messages: Mitochondrion matrix

931890:Ecym 6035
gene id: 931890:Ecym_6035
uniprot id: G8JUW0
names: Similarity
messages: Belongs to the oxoprolinase family.

931890:Ecym 3448
gene id: 931890:Ecym_3448
uniprot id: G8JS14
names: Subcellular Location Annotation
messages: Mitochondrion

931890:Ecym 7162
gene id: 931890:Ecym_7162
uniprot id: G8JVZ5
names: Similarity
messages: Belongs to the peptidase C12 family.

931890:Ecym 5262
gene id: 931890:Ecym_5262
uniprot id: I6ND85
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4166
gene id: 931890:Ecym_4166
uniprot id: G8JT90
names: Similarity
messages: Belongs to the PI3/PI4-kinase family. Type III PI4K subfamily.

931890:Ecym 2450
gene id: 931890:Ecym_2450
uniprot id: G8JPC0
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2094
gene id: 931890:Ecym_2094
uniprot id: G8JPJ8
names: Function
names: Similarity
messages: Belongs to the CTR86 family.
messages: Essential protein which may be involved in threonine biosynthesis.

931890:Ecym 8310
gene id: 931890:Ecym_8310
uniprot id: G8JXL4
names: Function
names: PTM
names: Similarity
messages: Belongs to the NAPRTase family.
messages: Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.
messages: Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.

931890:Ecym 6101
gene id: 931890:Ecym_6101
uniprot id: G8JV17
names: Similarity
messages: Belongs to the SOS response-associated peptidase family.

931890:Ecym 5452
gene id: 931890:Ecym_5452
uniprot id: I6NDQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTL (choline transporter-like) family.
messages: Cell membrane
messages: Membrane
messages: Probably involved in transport through the plasma membrane.

931890:Ecym 7378
gene id: 931890:Ecym_7378
uniprot id: G8JWI9
names: Similarity
names: Subunit
messages: Homodimer.
messages: In the C-terminal section; belongs to the formate--tetrahydrofolate ligase family.
messages: In the N-terminal section; belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

931890:Ecym 2793
gene id: 931890:Ecym_2793
uniprot id: G8JQ28
names: Subunit
messages: Monomer.

931890:Ecym 7426
gene id: 931890:Ecym_7426
uniprot id: G8JWN4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AAA ATPase family.
messages: Cytoplasm
messages: Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack independent of vesicle origin.

931890:Ecym 7046
gene id: 931890:Ecym_7046
uniprot id: G8JVN7
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL21 family.

931890:Ecym 1522
gene id: 931890:Ecym_1522
uniprot id: G8JMS9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPCS3 family.
messages: Endoplasmic reticulum membrane

931890:Ecym 8066
gene id: 931890:Ecym_8066
uniprot id: G8JWY8
names: Similarity
messages: Belongs to the biotin--protein ligase family.

931890:Ecym 3439
gene id: 931890:Ecym_3439
uniprot id: G8JS05
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ATPase alpha/beta chains family.
messages: Non-catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex attached to an integral membrane V0 proton pore complex.

931890:Ecym 3031
gene id: 931890:Ecym_3031
uniprot id: G8JQX7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 5117
gene id: 931890:Ecym_5117
uniprot id: I6NCV5
names: Function
names: Subcellular Location Annotation
names: Subunit
messages: COPI-coated vesicle membrane
messages: Cytoplasm
messages: Golgi apparatus membrane
messages: Membrane
messages: Oligomeric complex that consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits.
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

931890:Ecym 7197
gene id: 931890:Ecym_7197
uniprot id: G8JW30
names: Similarity
messages: Belongs to the pyrroline-5-carboxylate reductase family.

931890:Ecym 6259
gene id: 931890:Ecym_6259
uniprot id: G8JVG2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAF7 family.
messages: Nucleus

931890:Ecym 6085
gene id: 931890:Ecym_6085
uniprot id: G8JV02
names: Similarity
messages: Belongs to the PurH family.

931890:Ecym 8114
gene id: 931890:Ecym_8114
uniprot id: G8JX34
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the replication factor A protein 3 family.
messages: Nucleus

931890:Ecym 3097
gene id: 931890:Ecym_3097
uniprot id: G8JR37
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Ran family.
messages: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.
messages: Nucleus

931890:Ecym 4350
gene id: 931890:Ecym_4350
uniprot id: G8JTQ8
names: Similarity
messages: Belongs to the peptidase C48 family.

931890:Ecym 2781
gene id: 931890:Ecym_2781
uniprot id: G8JQ16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the purine-cytosine permease (2.A.39) family.
messages: Membrane

931890:Ecym 2138
gene id: 931890:Ecym_2138
uniprot id: G8JNH4
names: Similarity
messages: Belongs to the helicase family. RecQ subfamily.

931890:Ecym 4272
gene id: 931890:Ecym_4272
uniprot id: G8JTI3
names: Similarity
messages: Belongs to the REXO1/REXO3 family.

931890:Ecym 8089
gene id: 931890:Ecym_8089
uniprot id: G8JX10
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex SPC34 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 2136
gene id: 931890:Ecym_2136
uniprot id: G8JNH2
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL28 family.

931890:Ecym 1305
gene id: 931890:Ecym_1305
uniprot id: G8JN79
names: Similarity
messages: Belongs to the acetolactate synthase small subunit family.

931890:Ecym 4348
gene id: 931890:Ecym_4348
uniprot id: G8JTQ6
names: Similarity
messages: Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.

931890:Ecym 5351
gene id: 931890:Ecym_5351
uniprot id: I6NDG8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 1251
gene id: 931890:Ecym_1251
uniprot id: G8JN30
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8255
gene id: 931890:Ecym_8255
uniprot id: G8JXG4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

931890:Ecym 7287
gene id: 931890:Ecym_7287
uniprot id: G8JWB0
names: Function
names: Similarity
messages: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
messages: NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate.

931890:Ecym 6054
gene id: 931890:Ecym_6054
uniprot id: G8JUX8
names: Similarity
messages: Belongs to the SIP5 family.

931890:Ecym 4439
gene id: 931890:Ecym_4439
uniprot id: G8JTY2
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1290
gene id: 931890:Ecym_1290
uniprot id: G8JN65
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family. UEV subfamily.

931890:Ecym 4679
gene id: 931890:Ecym_4679
uniprot id: G8JSH8
names: Similarity
messages: Belongs to the AAR2 family.

931890:Ecym 1100
gene id: 931890:Ecym_1100
uniprot id: G8JME7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5145
gene id: 931890:Ecym_5145
uniprot id: I6NCY0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 39 family.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins.

931890:Ecym 7445
gene id: 931890:Ecym_7445
uniprot id: G8JWQ0
names: Similarity
messages: Belongs to the GTP cyclohydrolase II family.

931890:Ecym 5249
gene id: 931890:Ecym_5249
uniprot id: I6ND73
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSBP family.
messages: Membrane

931890:Ecym 3383
gene id: 931890:Ecym_3383
uniprot id: G8JRV1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA mismatch repair MutL/HexB family.
messages: Nucleus

931890:Ecym 6263
gene id: 931890:Ecym_6263
uniprot id: G8JVG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.
messages: Membrane

931890:Ecym 6195
gene id: 931890:Ecym_6195
uniprot id: G8JV99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the VPS10-related sortilin family.
messages: Membrane
messages: trans-Golgi network membrane

931890:Ecym 5553
gene id: 931890:Ecym_5553
uniprot id: I6NE01
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2200
gene id: 931890:Ecym_2200
uniprot id: G8JP44
names: Subcellular Location Annotation
messages: Cell surface

931890:Ecym 3154
gene id: 931890:Ecym_3154
uniprot id: G8JR88
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

931890:Ecym 1255
gene id: 931890:Ecym_1255
uniprot id: G8JN33
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SURF1 family.
messages: Mitochondrion inner membrane
messages: Probably involved in the biogenesis of the COX complex.

931890:Ecym 4552
gene id: 931890:Ecym_4552
uniprot id: G8JU84
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PNO1 family.
messages: Component of the small ribosomal subunit, ribosomal RNA processing complex (SSU RRP complex).
messages: Required for small ribosomal subunit (SSU) synthesis. Has a role in the processing of early nucleolar and late cytoplasmic pre-RNA species.

931890:Ecym 4554
gene id: 931890:Ecym_4554
uniprot id: G8JU86
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5476
gene id: 931890:Ecym_5476
uniprot id: I6NDT0
names: Similarity
messages: Belongs to the SGT1 family.

931890:Ecym 4479
gene id: 931890:Ecym_4479
uniprot id: G8JU16
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FMP52 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 1388
gene id: 931890:Ecym_1388
uniprot id: G8JM48
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 8266
gene id: 931890:Ecym_8266
uniprot id: G8JXH4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

931890:Ecym 4139
gene id: 931890:Ecym_4139
uniprot id: G8JT65
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 3058
gene id: 931890:Ecym_3058
uniprot id: G8JR01
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MON1/SAND family.
messages: Prevacuolar compartment membrane
messages: Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis.
messages: Vacuole membrane
messages: multivesicular body membrane

931890:Ecym 7218
gene id: 931890:Ecym_7218
uniprot id: G8JW49
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SecE/SEC61-gamma family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 8009
gene id: 931890:Ecym_8009
uniprot id: G8JXX9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the IPI1/TEX10 family.
messages: Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.
messages: Component of the RIX1 complex, composed of IPI1, RIX1/IPI2 and IPI3 in a 1:2:2 stoichiometry. The complex interacts (via RIX1) with MDN1 (via its hexameric AAA ATPase ring) and the pre-60S ribosome particles.
messages: Nucleus

931890:Ecym 7250
gene id: 931890:Ecym_7250
uniprot id: G8JW79
names: Cofactor
names: PTM
names: Similarity
messages: Belongs to the copper/topaquinone oxidase family.
messages: Contains 1 topaquinone per subunit.
messages: Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.

931890:Ecym 7395
gene id: 931890:Ecym_7395
uniprot id: G8JWK6
names: Function
messages: Involved in amino sugar synthesis (formation of chitin, supplies the amino sugars of asparagine-linked oligosaccharides of glycoproteins).

931890:Ecym 1247
gene id: 931890:Ecym_1247
uniprot id: G8JN26
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
messages: Membrane

931890:Ecym 8102
gene id: 931890:Ecym_8102
uniprot id: G8JX22
names: Similarity
messages: Belongs to the FPP/GGPP synthase family.

931890:Ecym 1508
gene id: 931890:Ecym_1508
uniprot id: G8JMR7
names: Caution
messages: Lacks conserved residue(s) required for the propagation of feature annotation.

931890:Ecym 7280
gene id: 931890:Ecym_7280
uniprot id: G8JWA6
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GTR/RAG GTP-binding protein family.
messages: Component of the GSE complex.
messages: GTPase involved in activation of the TORC1 signaling pathway, which promotes growth and represses autophagy in nutrient-rich conditions.

931890:Ecym 8038
gene id: 931890:Ecym_8038
uniprot id: G8JWW0
names: Similarity
messages: Belongs to the cyclin family.

931890:Ecym 1090
gene id: 931890:Ecym_1090
uniprot id: G8JMD8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TAM41 family.
messages: Mitochondrion inner membrane

931890:Ecym 2629
gene id: 931890:Ecym_2629
uniprot id: G8JQK9
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931890:Ecym 4099
gene id: 931890:Ecym_4099
uniprot id: G8JT25
names: Function
names: Subcellular Location Annotation
messages: Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation.
messages: Nucleus

931890:Ecym 7478
gene id: 931890:Ecym_7478
uniprot id: G8JWT0
names: Similarity
messages: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.

931890:Ecym 6399
gene id: 931890:Ecym_6399
uniprot id: G8JUJ3
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 8258
gene id: 931890:Ecym_8258
uniprot id: G8JXG6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MAD2 family.
messages: Nucleus

931890:Ecym 7339
gene id: 931890:Ecym_7339
uniprot id: G8JWF4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the ALAD family.
messages: Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
messages: Homooctamer.

931890:Ecym 6430
gene id: 931890:Ecym_6430
uniprot id: G8JUM1
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Tim17/Tim22/Tim23 family.
messages: Component of the TIM22 complex.
messages: Essential core component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. In the TIM22 complex, it constitutes the voltage-activated and signal-gated channel. Forms a twin-pore translocase that uses the membrane potential as external driving force in 2 voltage-dependent steps.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 1119
gene id: 931890:Ecym_1119
uniprot id: G8JML8
names: Function
names: Similarity
messages: Catalyzes three sequential steps of tetrahydrofolate biosynthesis.
messages: In the C-terminal section; belongs to the DHPS family.
messages: In the N-terminal section; belongs to the DHNA family.
messages: In the central section; belongs to the HPPK family.

931890:Ecym 3256
gene id: 931890:Ecym_3256
uniprot id: G8JRI0
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 5649
gene id: 931890:Ecym_5649
uniprot id: I6NE92
names: Subcellular Location Annotation
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 3239
gene id: 931890:Ecym_3239
uniprot id: G8JRG4
names: Function
names: Similarity
names: Subunit
messages: Belongs to the fungal fatty acid synthetase subunit beta family.
messages: Fatty acid synthetase catalyzes the formation of long-chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. The beta subunit contains domains for: [acyl-carrier-protein] acetyltransferase and malonyltransferase, S-acyl fatty acid synthase thioesterase, enoyl-[acyl-carrier-protein] reductase, and 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase.
messages: [Alpha(6)beta(6)] hexamers of two multifunctional subunits (alpha and beta).

931890:Ecym 4440
gene id: 931890:Ecym_4440
uniprot id: G8JTY3
names: Similarity
messages: Belongs to the universal ribosomal protein uS12 family.

931890:Ecym 4122
gene id: 931890:Ecym_4122
uniprot id: G8JT48
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.
messages: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
messages: Forms a complex with TRM82.
messages: Nucleus

931890:Ecym 3513
gene id: 931890:Ecym_3513
uniprot id: G8JS72
names: Similarity
messages: Belongs to the 14-3-3 family.

931890:Ecym 1379
gene id: 931890:Ecym_1379
uniprot id: G8JNE8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the V-ATPase proteolipid subunit family.
messages: Membrane
messages: Proton-conducting pore forming of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'', d, e, f and VOA1). The decameric c-ring forms the proton-conducting pore, and is composed of eight proteolipid subunits c, one subunit c' and one subunit c''.
messages: Vacuole membrane

931890:Ecym 3458
gene id: 931890:Ecym_3458
uniprot id: G8JS23
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family.
messages: Nucleus

931890:Ecym 8039
gene id: 931890:Ecym_8039
uniprot id: G8JWW1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
messages: Membrane
messages: Vacuole membrane

931890:Ecym 6235
gene id: 931890:Ecym_6235
uniprot id: G8JVD8
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Acts as an inhibitor of cap-dependent translation. Competes with eIF4G1 and EAP1 for binding to eIF4E and interferes with the formation of the eIF4F complex, inhibiting translation and stabilizing mRNA.
messages: Belongs to the CAF20 family.
messages: Cytoplasm

931890:Ecym 8416
gene id: 931890:Ecym_8416
uniprot id: G8JXW1
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL8 family.
messages: Component of the ribosome.

931890:Ecym 4744
gene id: 931890:Ecym_4744
uniprot id: G8JSN9
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NADPH--cytochrome P450 reductase family.
messages: Binds 1 FAD per monomer.
messages: Binds 1 FMN per monomer.
messages: Cell membrane
messages: Endoplasmic reticulum membrane
messages: In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.
messages: In the N-terminal section; belongs to the flavodoxin family.
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion outer membrane
messages: This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis.

931890:Ecym 5380
gene id: 931890:Ecym_5380
uniprot id: I6NDJ3
names: Similarity
messages: Belongs to the universal ribosomal protein uS13 family.

931890:Ecym 2606
gene id: 931890:Ecym_2606
uniprot id: G8JQI6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Tom20 family.
messages: Membrane
messages: Mitochondrion outer membrane

931890:Ecym 5194
gene id: 931890:Ecym_5194
uniprot id: I6ND23
names: Similarity
messages: Belongs to the glycosyltransferase 15 family.

931890:Ecym 3151
gene id: 931890:Ecym_3151
uniprot id: G8JR85
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YAE1 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 3304
gene id: 931890:Ecym_3304
uniprot id: G8JRM6
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
messages: Endoplasmic reticulum membrane
messages: Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum.

931890:Ecym 5502
gene id: 931890:Ecym_5502
uniprot id: I6NDV3
names: Similarity
messages: Belongs to the syntaxin family.

931890:Ecym 4013
gene id: 931890:Ecym_4013
uniprot id: G8JSU4
names: Similarity
messages: Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.

931890:Ecym 7237
gene id: 931890:Ecym_7237
uniprot id: G8JW68
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily.
messages: Cell membrane
messages: The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H(+)-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.

931890:Ecym 3069
gene id: 931890:Ecym_3069
uniprot id: G8JR12
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 31 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 7324
gene id: 931890:Ecym_7324
uniprot id: G8JWE3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DEAD box helicase family.
messages: nucleolus

931890:Ecym 4654
gene id: 931890:Ecym_4654
uniprot id: G8JSF4
names: Similarity
messages: Belongs to the MIX23 family.

931890:Ecym 4364
gene id: 931890:Ecym_4364
uniprot id: G8JTR9
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 6139
gene id: 931890:Ecym_6139
uniprot id: G8JV51
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

931890:Ecym 4450
gene id: 931890:Ecym_4450
uniprot id: G8JTZ2
names: Similarity
messages: Belongs to the archaeal Rpo3/eukaryotic RPB3 RNA polymerase subunit family.

931890:Ecym 5517
gene id: 931890:Ecym_5517
uniprot id: I6NDW7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EAF1 family.
messages: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.
messages: Nucleus

931890:Ecym 4755
gene id: 931890:Ecym_4755
uniprot id: G8JSP6
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 4176
gene id: 931890:Ecym_4176
uniprot id: G8JT99
names: Function
names: Similarity
messages: Belongs to the cytidine and deoxycytidylate deaminase family.
messages: This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

931890:Ecym 2480
gene id: 931890:Ecym_2480
uniprot id: G8JPU5
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2101
gene id: 931890:Ecym_2101
uniprot id: G8JPK5
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.
messages: Endoplasmic reticulum membrane
messages: Membrane
messages: Sterol O-acyltransferase that catalyzes the formation of stery esters.

931890:Ecym 5122
gene id: 931890:Ecym_5122
uniprot id: I6NCV9
names: Similarity
messages: Belongs to the HMBS family.

931890:Ecym 2674
gene id: 931890:Ecym_2674
uniprot id: G8JNV9
names: Similarity
messages: Belongs to the glycosyl hydrolase 81 family.

931890:Ecym 2320
gene id: 931890:Ecym_2320
uniprot id: G8JQ60
names: Function
names: Similarity
names: Subunit
messages: Belongs to the VPS17 family.
messages: Component of the retromer complex.
messages: Plays a role in vesicular protein sorting.

931890:Ecym 1423
gene id: 931890:Ecym_1423
uniprot id: G8JM80
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPC1 family.
messages: Membrane

931890:Ecym 4269
gene id: 931890:Ecym_4269
uniprot id: G8JTI0
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1348
gene id: 931890:Ecym_1348
uniprot id: G8JNB8
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 4304
gene id: 931890:Ecym_4304
uniprot id: G8JTL4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GEP5 family.
messages: Essential for respiratory growth and required for maintenance of mtDNA. Required for cell survival in the absence of prohibitins.
messages: Mitochondrion

931890:Ecym 7293
gene id: 931890:Ecym_7293
uniprot id: G8JWB6
names: Similarity
messages: Belongs to the peptidase M24B family.

931890:Ecym 7463
gene id: 931890:Ecym_7463
uniprot id: G8JWR7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COPE family.
messages: Cytoplasm
messages: Membrane
messages: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.

931890:Ecym 8206
gene id: 931890:Ecym_8206
uniprot id: G8JXB7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CTU2/NCS2 family.
messages: Cytoplasm
messages: Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation.

931890:Ecym 4303
gene id: 931890:Ecym_4303
uniprot id: G8JTL3
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL34 family.

931890:Ecym 2498
gene id: 931890:Ecym_2498
uniprot id: G8JPW2
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 1426
gene id: 931890:Ecym_1426
uniprot id: G8JM83
names: Cofactor
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the myo-inositol oxygenase family.
messages: Binds 2 iron ions per subunit.
messages: Cytoplasm

931890:Ecym 8384
gene id: 931890:Ecym_8384
uniprot id: G8JXT0
names: Similarity
messages: Belongs to the CWC26 family.

931890:Ecym 2414
gene id: 931890:Ecym_2414
uniprot id: G8JP88
names: Similarity
messages: Belongs to the dihydrofolate reductase family.

931890:Ecym 4721
gene id: 931890:Ecym_4721
uniprot id: G8JSL9
names: Similarity
messages: Belongs to the prefoldin subunit beta family.

931890:Ecym 3362
gene id: 931890:Ecym_3362
uniprot id: G8JRT0
names: Similarity
messages: Belongs to the IWR1/SLC7A6OS family.

931890:Ecym 5152
gene id: 931890:Ecym_5152
uniprot id: I6NCY6
names: Similarity
messages: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.

931890:Ecym 4143
gene id: 931890:Ecym_4143
uniprot id: G8JT68
names: Similarity
messages: Belongs to the AHA1 family.

931890:Ecym 2361
gene id: 931890:Ecym_2361
uniprot id: G8JNM7
names: Function
names: Similarity
names: Subunit
messages: Belongs to the GPN-loop GTPase family.
messages: Binds to RNA polymerase II (RNAPII).
messages: Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import.

931890:Ecym 4119
gene id: 931890:Ecym_4119
uniprot id: G8JT45
names: Similarity
messages: Belongs to the DODA-type extradiol aromatic ring-opening dioxygenase family.

931890:Ecym 6177
gene id: 931890:Ecym_6177
uniprot id: G8JV81
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM5 family.
messages: Cytoplasm
messages: S-adenosyl-L-methionine-dependent protein-lysine N-methyltransferase that trimethylates elongation factor 1-alpha at 'Lys-79'.

931890:Ecym 3378
gene id: 931890:Ecym_3378
uniprot id: G8JRU6
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2039
gene id: 931890:Ecym_2039
uniprot id: G8JNZ7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.
messages: Membrane

931890:Ecym 2698
gene id: 931890:Ecym_2698
uniprot id: G8JPD9
names: Similarity
messages: Belongs to the PPase family.

931890:Ecym 5563
gene id: 931890:Ecym_5563
uniprot id: I6NE10
names: Similarity
messages: Belongs to the ubiquitin-conjugating enzyme family.

931890:Ecym 7231
gene id: 931890:Ecym_7231
uniprot id: G8JW62
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SLA1 family.
messages: Cell membrane
messages: Endosome membrane
messages: Membrane

931890:Ecym 4763
gene id: 931890:Ecym_4763
uniprot id: G8JSQ3
names: Similarity
messages: Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.

931890:Ecym 2041
gene id: 931890:Ecym_2041
uniprot id: G8JNZ8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the UPF0220 family.
messages: Membrane

931890:Ecym 7066
gene id: 931890:Ecym_7066
uniprot id: G8JVQ4
names: Subcellular Location Annotation
messages: Mitochondrion outer membrane

931890:Ecym 4340
gene id: 931890:Ecym_4340
uniprot id: G8JTP8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.
messages: Membrane

931890:Ecym 2589
gene id: 931890:Ecym_2589
uniprot id: G8JQH1
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the NFYA/HAP2 subunit family.
messages: Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'-CCAAT-3' box motif found in the promoters of its target genes.
messages: Heterotrimer.
messages: Nucleus

931890:Ecym 3404
gene id: 931890:Ecym_3404
uniprot id: G8JRX1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c-type heme lyase family.
messages: Lyase that catalyzes the covalent linking of the heme group to the cytochrome C apoprotein to produce the mature functional cytochrome.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 3414
gene id: 931890:Ecym_3414
uniprot id: G8JRY1
names: Function
names: Similarity
names: Subunit
messages: Belongs to the V-ATPase C subunit family.
messages: Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons. V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it is responsible for acidifying the extracellular environment. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity.
messages: V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex.

931890:Ecym 2256
gene id: 931890:Ecym_2256
uniprot id: G8JPP7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SNF2/RAD54 helicase family. ISWI subfamily.
messages: Nucleus

931890:Ecym 5393
gene id: 931890:Ecym_5393
uniprot id: I6NDK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane

931890:Ecym 7465
gene id: 931890:Ecym_7465
uniprot id: G8JWR9
names: Similarity
messages: Belongs to the universal ribosomal protein uS15 family.

931890:Ecym 6069
gene id: 931890:Ecym_6069
uniprot id: G8JUZ0
names: Function
names: Similarity
messages: Belongs to the cytochrome c oxidase subunit 6B family.
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation.

931890:Ecym 2393
gene id: 931890:Ecym_2393
uniprot id: G8JNQ8
names: Similarity
messages: Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.

931890:Ecym 2759
gene id: 931890:Ecym_2759
uniprot id: G8JPZ5
names: Similarity
messages: Belongs to the universal ribosomal protein uS8 family.

931890:Ecym 6448
gene id: 931890:Ecym_6448
uniprot id: G8JUN9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RTT106 family.
messages: Chromosome
messages: Nucleus

931890:Ecym 6031
gene id: 931890:Ecym_6031
uniprot id: G8JUV7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the fluoride exporter Fluc/FEX family.
messages: Fluoride channel required for the rapid expulsion of cytoplasmic fluoride.
messages: Membrane

931890:Ecym 6262
gene id: 931890:Ecym_6262
uniprot id: G8JVG5
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 6347
gene id: 931890:Ecym_6347
uniprot id: G8JUE3
names: Similarity
messages: Belongs to the SAPS family.

931890:Ecym 5374
gene id: 931890:Ecym_5374
uniprot id: I6NDI7
names: Similarity
messages: Belongs to the END3 family.

931890:Ecym 5203
gene id: 931890:Ecym_5203
uniprot id: I6ND30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5573
gene id: 931890:Ecym_5573
uniprot id: I6NE19
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

931890:Ecym 4302
gene id: 931890:Ecym_4302
uniprot id: G8JTL2
names: Similarity
messages: Belongs to the universal ribosomal protein uL1 family.

931890:Ecym 1353
gene id: 931890:Ecym_1353
uniprot id: G8JNC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the beta-catenin family.
messages: Membrane
messages: Vacuole membrane

931890:Ecym 3482
gene id: 931890:Ecym_3482
uniprot id: G8JS46
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EXO84 family.
messages: Vesicle
messages: secretory vesicle

931890:Ecym 1429
gene id: 931890:Ecym_1429
uniprot id: G8JM85
names: Similarity
messages: In the C-terminal section; belongs to the TrpB family.
messages: In the N-terminal section; belongs to the TrpA family.

931890:Ecym 4051
gene id: 931890:Ecym_4051
uniprot id: G8JSX9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
messages: Belongs to the ALG6/ALG8 glucosyltransferase family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 5423
gene id: 931890:Ecym_5423
uniprot id: I6NDN5
names: Similarity
messages: Belongs to the archaeal Rpo11/eukaryotic RPB11/RPC19 RNA polymerase subunit family.

931890:Ecym 8138
gene id: 931890:Ecym_8138
uniprot id: G8JX55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase PH family.
messages: nucleolus

931890:Ecym 7129
gene id: 931890:Ecym_7129
uniprot id: G8JVW4
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL32 family.

931890:Ecym 1465
gene id: 931890:Ecym_1465
uniprot id: G8JMH4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.
messages: Membrane

931890:Ecym 8306
gene id: 931890:Ecym_8306
uniprot id: G8JXL0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the RNase T2 family.
messages: Rnase which modulates cell survival under stress conditions. Released from the vacuole to the cytoplasm during stress to promote tRNA and rRNA cleavage and to activate separately a downstream pathway that promotes cell death. Involved in cell size, vacuolar morphology and growth at high temperatures and high salt concentration.
messages: Vacuole lumen

931890:Ecym 1453
gene id: 931890:Ecym_1453
uniprot id: G8JMG2
names: Similarity
messages: Belongs to the acetyltransferase family. GNA1 subfamily.

931890:Ecym 1197
gene id: 931890:Ecym_1197
uniprot id: G8JMY1
names: Similarity
messages: Belongs to the GTP cyclohydrolase I type 2/NIF3 family.

931890:Ecym 8288
gene id: 931890:Ecym_8288
uniprot id: G8JXJ4
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
messages: Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
messages: Cytoplasm
messages: Homotrimer.
messages: Nucleus

931890:Ecym 3563
gene id: 931890:Ecym_3563
uniprot id: G8JQQ0
names: Similarity
messages: Belongs to the threonine aldolase family.

931890:Ecym 8159
gene id: 931890:Ecym_8159
uniprot id: G8JX72
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1360
gene id: 931890:Ecym_1360
uniprot id: G8JNC9
names: Similarity
messages: Belongs to the TPP enzyme family.

931890:Ecym 4402
gene id: 931890:Ecym_4402
uniprot id: G8JTV3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 22 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 8060
gene id: 931890:Ecym_8060
uniprot id: G8JWY2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 3194
gene id: 931890:Ecym_3194
uniprot id: G8JRC5
names: Similarity
messages: Belongs to the PIH1 family.

931890:Ecym 4568
gene id: 931890:Ecym_4568
uniprot id: G8JS79
names: Domain
names: Function
names: Similarity
messages: Belongs to the damage-control phosphatase family. Sugar phosphate phosphatase III subfamily.
messages: Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism.
messages: Subfamily III proteins have a conserved RTxK motif about 40-50 residues from the C-terminus; the threonine may be replaced by serine or cysteine.

931890:Ecym 1019
gene id: 931890:Ecym_1019
uniprot id: G8JM18
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily.
messages: Component of the nucleolar and nucleoplasmic pre-60S ribosomal particle.
messages: Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit.
messages: nucleolus

931890:Ecym 1328
gene id: 931890:Ecym_1328
uniprot id: G8JN99
names: Similarity
messages: Belongs to the pex2/pex10/pex12 family.

931890:Ecym 5603
gene id: 931890:Ecym_5603
uniprot id: I6NE47
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the OSW5 family.
messages: Involved in spore wall assembly.
messages: Membrane

931890:Ecym 1494
gene id: 931890:Ecym_1494
uniprot id: G8JMK1
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 1164
gene id: 931890:Ecym_1164
uniprot id: G8JMV0
names: Similarity
messages: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

931890:Ecym 8323
gene id: 931890:Ecym_8323
uniprot id: G8JXM7
names: Similarity
messages: Belongs to the peptidase S9B family.

931890:Ecym 2816
gene id: 931890:Ecym_2816
uniprot id: G8JQE9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG13 family. Fungi subfamily.
messages: Preautophagosomal structure

931890:Ecym 1338
gene id: 931890:Ecym_1338
uniprot id: G8JNA8
names: Similarity
messages: Belongs to the gamma-BBH/TMLD family.

931890:Ecym 3020
gene id: 931890:Ecym_3020
uniprot id: G8JQW8
names: Similarity
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.

931890:Ecym 1034
gene id: 931890:Ecym_1034
uniprot id: G8JM32
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EMC1 family.
messages: Component of the ER membrane protein complex (EMC).
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 4513
gene id: 931890:Ecym_4513
uniprot id: G8JU47
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GOLPH3/VPS74 family.
messages: Membrane

931890:Ecym 8293
gene id: 931890:Ecym_8293
uniprot id: G8JXJ8
names: Similarity
messages: Belongs to the IPP isomerase type 1 family.

931890:Ecym 2489
gene id: 931890:Ecym_2489
uniprot id: G8JPV3
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7125
gene id: 931890:Ecym_7125
uniprot id: G8JVW0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the aromatic-ring hydroxylase family. KMO subfamily.
messages: Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
messages: Mitochondrion outer membrane

931890:Ecym 3187
gene id: 931890:Ecym_3187
uniprot id: G8JRB7
names: Similarity
messages: Belongs to the aldehyde dehydrogenase family.

931890:Ecym 4115
gene id: 931890:Ecym_4115
uniprot id: G8JT41
names: Function
names: Subcellular Location Annotation
messages: Acts as component of the general transcription and DNA repair factor IIH (TFIIH or factor B), which is essential for both basal and activated transcription, and is involved in nucleotide excision repair (NER) of damaged DNA.
messages: Nucleus

931890:Ecym 3457
gene id: 931890:Ecym_3457
uniprot id: G8JS22
names: Function
names: Similarity
messages: Belongs to the ATP-dependent AMP-binding enzyme family.
messages: Catalyzes the activation of alpha-aminoadipate by ATP-dependent adenylation and the reduction of activated alpha-aminoadipate by NADPH. The activated alpha-aminoadipate is bound to the phosphopantheinyl group of the enzyme itself before it is reduced to (S)-2-amino-6-oxohexanoate.

931890:Ecym 5284
gene id: 931890:Ecym_5284
uniprot id: I6NDA4
names: Similarity
messages: Belongs to the sirtuin family. Class I subfamily.

931890:Ecym 1162
gene id: 931890:Ecym_1162
uniprot id: G8JMU8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: Binds specifically to the 3'-terminal U-tract of U6 snRNA.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus

931890:Ecym 2662
gene id: 931890:Ecym_2662
uniprot id: G8JNU7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid-polyamine-organocation (APC) superfamily. YAT (TC 2.A.3.10) family.
messages: Membrane

931890:Ecym 5566
gene id: 931890:Ecym_5566
uniprot id: I6NE12
names: Similarity
messages: Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.

931890:Ecym 6165
gene id: 931890:Ecym_6165
uniprot id: G8JV71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family.
messages: Catalyzes the hydrolysis of ATP coupled with the transport of calcium.
messages: Membrane

931890:Ecym 7388
gene id: 931890:Ecym_7388
uniprot id: G8JWJ9
names: Similarity
messages: Belongs to the thioredoxin family.

931890:Ecym 2441
gene id: 931890:Ecym_2441
uniprot id: G8JPB3
names: Function
names: Similarity
names: Subunit
messages: Belongs to the F-actin-capping protein alpha subunit family.
messages: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
messages: Heterodimer of an alpha and a beta subunit.

931890:Ecym 5106
gene id: 931890:Ecym_5106
uniprot id: I6NCU6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SVP26 family.
messages: Membrane

931890:Ecym 1362
gene id: 931890:Ecym_1362
uniprot id: G8JND1
names: Similarity
messages: Belongs to the small Tim family.

931890:Ecym 6170
gene id: 931890:Ecym_6170
uniprot id: G8JV76
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2497
gene id: 931890:Ecym_2497
uniprot id: G8JPW1
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL49 family.
messages: Mitochondrion

931890:Ecym 6375
gene id: 931890:Ecym_6375
uniprot id: G8JUH0
names: Similarity
messages: Belongs to the CAP family.

931890:Ecym 6222
gene id: 931890:Ecym_6222
uniprot id: G8JVC5
names: Function
names: Similarity
messages: Belongs to the gamma-glutamylcyclotransferase family.
messages: Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides.

931890:Ecym 7105
gene id: 931890:Ecym_7105
uniprot id: G8JVU2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat DCAF13/WDSOF1 family.
messages: nucleolus

931890:Ecym 7001
gene id: 931890:Ecym_7001
uniprot id: G8JVJ5
names: Similarity
messages: Belongs to the glutaminase PdxT/SNO family.

931890:Ecym 2510
gene id: 931890:Ecym_2510
uniprot id: G8JPX3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the ARPC2 family.
messages: Component of the Arp2/3 complex.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
messages: cytoskeleton

931890:Ecym 8295
gene id: 931890:Ecym_8295
uniprot id: G8JXK0
names: Similarity
messages: Belongs to the imidazoleglycerol-phosphate dehydratase family.

931890:Ecym 3202
gene id: 931890:Ecym_3202
uniprot id: G8JRD2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 6 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 2755
gene id: 931890:Ecym_2755
uniprot id: G8JPZ1
names: Similarity
messages: Belongs to the protein-tyrosine phosphatase family. Non-receptor class CDC14 subfamily.

931890:Ecym 1509
gene id: 931890:Ecym_1509
uniprot id: G8JMR8
names: Similarity
names: Subunit
messages: Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 2 subfamily.
messages: Tetramer of two alpha and two beta subunits.

931890:Ecym 6264
gene id: 931890:Ecym_6264
uniprot id: G8JVG7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal membrane protein PXMP2/4 family.
messages: Membrane

931890:Ecym 1435
gene id: 931890:Ecym_1435
uniprot id: G8JM91
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STT3 family.
messages: Membrane

931890:Ecym 5329
gene id: 931890:Ecym_5329
uniprot id: I6NDE6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CSC1 (TC 1.A.17) family.
messages: Membrane

931890:Ecym 2452
gene id: 931890:Ecym_2452
uniprot id: G8JPC2
names: Similarity
names: Subunit
messages: Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
messages: Homotetramer. Residues from neighboring subunits contribute catalytic and substrate-binding residues to each active site.

931890:Ecym 6396
gene id: 931890:Ecym_6396
uniprot id: G8JUJ0
names: Function
names: Similarity
names: Subunit
messages: Belongs to the prefoldin subunit beta family.
messages: Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
messages: Heterohexamer of two PFD-alpha type and four PFD-beta type subunits.

931890:Ecym 4461
gene id: 931890:Ecym_4461
uniprot id: G8JU00
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6354
gene id: 931890:Ecym_6354
uniprot id: G8JUF0
names: Subcellular Location Annotation
messages: nucleolus

931890:Ecym 4765
gene id: 931890:Ecym_4765
uniprot id: G8JSQ5
names: Similarity
messages: Belongs to the EFG1 family.

931890:Ecym 1521
gene id: 931890:Ecym_1521
uniprot id: G8JMS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
messages: Membrane

931890:Ecym 2253
gene id: 931890:Ecym_2253
uniprot id: G8JPP4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the USE1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 3365
gene id: 931890:Ecym_3365
uniprot id: G8JRT3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the nucleoporin Nup84/Nup107 family.
messages: Functions as a component of the nuclear pore complex (NPC).
messages: Nucleus membrane
messages: Part of the nuclear pore complex (NPC).
messages: nuclear pore complex

931890:Ecym 4118
gene id: 931890:Ecym_4118
uniprot id: G8JT44
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX20 family.
messages: Involved in the assembly of the cytochrome c oxidase complex.
messages: Mitochondrion inner membrane

931890:Ecym 1115
gene id: 931890:Ecym_1115
uniprot id: G8JM02
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8052
gene id: 931890:Ecym_8052
uniprot id: G8JWX4
names: Similarity
messages: Belongs to the PPP phosphatase family.

931890:Ecym 3216
gene id: 931890:Ecym_3216
uniprot id: G8JRE4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TFB1 family.
messages: Nucleus

931890:Ecym 3203
gene id: 931890:Ecym_3203
uniprot id: G8JRD3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mS41 family.
messages: Mitochondrion

931890:Ecym 3129
gene id: 931890:Ecym_3129
uniprot id: G8JR64
names: Similarity
messages: Belongs to the GET4 family.

931890:Ecym 2679
gene id: 931890:Ecym_2679
uniprot id: G8JNW4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 7382
gene id: 931890:Ecym_7382
uniprot id: G8JWJ3
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the snRNP Sm proteins family.
messages: LSm subunits form a heteromer with a doughnut shape.
messages: Nucleus
messages: Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.

931890:Ecym 8188
gene id: 931890:Ecym_8188
uniprot id: G8JX99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the RNA cytidine acetyltransferase family. NAT10 subfamily.
messages: Interacts with TAN1.
messages: RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA-binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
messages: nucleolus

931890:Ecym 5669
gene id: 931890:Ecym_5669
uniprot id: I6NEA9
names: Similarity
messages: Belongs to the CWC22 family.

931890:Ecym 4276
gene id: 931890:Ecym_4276
uniprot id: G8JTI7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CDC45 family.
messages: Nucleus

931890:Ecym 2442
gene id: 931890:Ecym_2442
uniprot id: G8JPB4
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 3317
gene id: 931890:Ecym_3317
uniprot id: G8JRN9
names: Similarity
messages: Belongs to the FYV10 family.

931890:Ecym 4107
gene id: 931890:Ecym_4107
uniprot id: G8JT33
names: Similarity
messages: Belongs to the guanylate kinase family.

931890:Ecym 8112
gene id: 931890:Ecym_8112
uniprot id: G8JX32
names: Similarity
messages: Belongs to the peptidase M20A family.

931890:Ecym 4411
gene id: 931890:Ecym_4411
uniprot id: G8JTW0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ammonia transporter channel (TC 1.A.11.2) family.
messages: Cell membrane
messages: Membrane

931890:Ecym 8108
gene id: 931890:Ecym_8108
uniprot id: G8JX28
names: Subcellular Location Annotation
messages: Chromosome
messages: Nucleus

931890:Ecym 4100
gene id: 931890:Ecym_4100
uniprot id: G8JT26
names: Similarity
messages: Belongs to the UTP6 family.

931890:Ecym 1275
gene id: 931890:Ecym_1275
uniprot id: G8JN52
names: Similarity
messages: Belongs to the protein kinase superfamily.

931890:Ecym 2088
gene id: 931890:Ecym_2088
uniprot id: G8JPJ2
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the universal ribosomal protein uS2 family.
messages: Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with RPS21.
messages: Cytoplasm
messages: Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.

931890:Ecym 3552
gene id: 931890:Ecym_3552
uniprot id: G8JQP1
names: Function
names: Similarity
messages: Belongs to the inositol monophosphatase superfamily.
messages: Converts adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS) and 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.

931890:Ecym 3231
gene id: 931890:Ecym_3231
uniprot id: G8JRF6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS36 family.
messages: Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs.
messages: Component of the endosomal sorting complex required for transport II (ESCRT-II).
messages: Cytoplasm
messages: Endosome

931890:Ecym 2186
gene id: 931890:Ecym_2186
uniprot id: G8JP30
names: Similarity
messages: Belongs to the U2 small nuclear ribonucleoprotein A family.

931890:Ecym 2571
gene id: 931890:Ecym_2571
uniprot id: G8JQD0
names: Similarity
messages: Belongs to the MsrA Met sulfoxide reductase family.

931890:Ecym 8307
gene id: 931890:Ecym_8307
uniprot id: G8JXL1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SPC29 family.
messages: Component of the spindle pole body (SPB) required for the proper execution of spindle pole body (SPB) duplication. Links the central plaque component SPC42 to the inner plaque component SPC110.
messages: Nucleus
messages: spindle pole body

931890:Ecym 7233
gene id: 931890:Ecym_7233
uniprot id: G8JW64
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1A family.
messages: Cytoplasm
messages: Nucleus
messages: The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity.

931890:Ecym 4183
gene id: 931890:Ecym_4183
uniprot id: G8JTA6
names: Function
names: Similarity
messages: Belongs to the SEC10 family.
messages: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.

931890:Ecym 3396
gene id: 931890:Ecym_3396
uniprot id: G8JRW4
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ARPC4 family.
messages: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.
messages: actin patch

931890:Ecym 2235
gene id: 931890:Ecym_2235
uniprot id: G8JP77
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily.
messages: Binds 4 [4Fe-4S] clusters per heterotetramer. Contains two stable clusters in the N-termini of NBP35 and two labile, bridging clusters between subunits of the NBP35-CFD1 heterotetramer.
messages: Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export.
messages: Cytoplasm
messages: Heterotetramer of 2 NBP35 and 2 CFD1 chains.
messages: Nucleus

931890:Ecym 1091
gene id: 931890:Ecym_1091
uniprot id: G8JMD9
names: Similarity
messages: Belongs to the IST1 family.

931890:Ecym 8249
gene id: 931890:Ecym_8249
uniprot id: G8JXF8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the amino acid/polyamine transporter 2 family.
messages: Vacuole membrane

931890:Ecym 8133
gene id: 931890:Ecym_8133
uniprot id: G8JX50
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SOP4 family.
messages: Endoplasmic reticulum membrane
messages: Involved in the export of PMA1, possibly through the monitoring or assisting of PMA1 folding and acquisition of competence to enter vesicles.
messages: Membrane

931890:Ecym 8250
gene id: 931890:Ecym_8250
uniprot id: G8JXF9
names: Similarity
messages: Belongs to the AAA ATPase family.

931890:Ecym 4740
gene id: 931890:Ecym_4740
uniprot id: G8JSN5
names: Function
names: Subcellular Location Annotation
messages: Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.
messages: Nucleus

931890:Ecym 6102
gene id: 931890:Ecym_6102
uniprot id: G8JV18
names: Similarity
messages: Belongs to the folylpolyglutamate synthase family.

931890:Ecym 1342
gene id: 931890:Ecym_1342
uniprot id: G8JNB2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DNA polymerase type-X family.
messages: DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template-independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
messages: Nucleus

931890:Ecym 6489
gene id: 931890:Ecym_6489
uniprot id: G8JUS7
names: Function
names: Similarity
messages: Belongs to the glucose-6-phosphate dehydrogenase family.
messages: Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. The main function of this enzyme is to provide reducing power (NADPH) and pentose phosphates for fatty acid and nucleic acid synthesis.

931890:Ecym 2737
gene id: 931890:Ecym_2737
uniprot id: G8JPH0
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4722
gene id: 931890:Ecym_4722
uniprot id: G8JSM0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COQ9 family.
messages: Lipid-binding protein involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration.
messages: Mitochondrion

931890:Ecym 3245
gene id: 931890:Ecym_3245
uniprot id: G8JRG9
names: Similarity
messages: Belongs to the BLOC1S1 family.

931890:Ecym 5018
gene id: 931890:Ecym_5018
uniprot id: I6NCM7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial Rho GTPase family.
messages: Membrane
messages: Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution.
messages: Mitochondrion outer membrane

931890:Ecym 4494
gene id: 931890:Ecym_4494
uniprot id: G8JU30
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 7069
gene id: 931890:Ecym_7069
uniprot id: G8JVQ7
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 5632
gene id: 931890:Ecym_5632
uniprot id: I6NE76
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrial carrier (TC 2.A.29) family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 5616
gene id: 931890:Ecym_5616
uniprot id: I6NE60
names: Similarity
messages: Belongs to the proteasome subunit S9 family.

931890:Ecym 2047
gene id: 931890:Ecym_2047
uniprot id: G8JP04
names: Function
names: Similarity
messages: Belongs to the methyltransferase TRM13 family.
messages: tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).

931890:Ecym 1235
gene id: 931890:Ecym_1235
uniprot id: G8JN17
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the prohibitin family.
messages: Mitochondrion inner membrane

931890:Ecym 3430
gene id: 931890:Ecym_3430
uniprot id: G8JRZ7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2135
gene id: 931890:Ecym_2135
uniprot id: G8JNH1
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL36 family.

931890:Ecym 1396
gene id: 931890:Ecym_1396
uniprot id: G8JM55
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxisomal targeting signal receptor family.
messages: Cytoplasm
messages: Membrane
messages: Peroxisome membrane

931890:Ecym 6066
gene id: 931890:Ecym_6066
uniprot id: G8JUY7
names: Similarity
messages: Belongs to the CCDC25 family.

931890:Ecym 4103
gene id: 931890:Ecym_4103
uniprot id: G8JT29
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 2143
gene id: 931890:Ecym_2143
uniprot id: G8JNH9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the SRP68 family.
messages: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). The SRP complex interacts with the signal sequence in nascent secretory and membrane proteins and directs them to the membrane of the ER.
messages: Cytoplasm
messages: nucleolus

931890:Ecym 3374
gene id: 931890:Ecym_3374
uniprot id: G8JRU2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyltransferase 22 family. PIGB subfamily.
messages: Endoplasmic reticulum membrane
messages: Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly.
messages: Membrane

931890:Ecym 1330
gene id: 931890:Ecym_1330
uniprot id: G8JNA1
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 5286
gene id: 931890:Ecym_5286
uniprot id: I6NDA6
names: Similarity
messages: Belongs to the AAA ATPase family.

931890:Ecym 5399
gene id: 931890:Ecym_5399
uniprot id: I6NDL2
names: Similarity
messages: Belongs to the SUN family.

931890:Ecym 5639
gene id: 931890:Ecym_5639
uniprot id: I6NE83
names: Similarity
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

931890:Ecym 2035
gene id: 931890:Ecym_2035
uniprot id: G8JNZ3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the glycosyl hydrolase 72 family.
messages: Cell membrane
messages: Membrane
messages: Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non-reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3-beta-glucan chains in the cell wall.

931890:Ecym 4146
gene id: 931890:Ecym_4146
uniprot id: G8JT71
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily.
messages: Cell membrane
messages: Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state.

931890:Ecym 6045
gene id: 931890:Ecym_6045
uniprot id: G8JUW9
names: Similarity
messages: Belongs to the cytochrome P450 family.

931890:Ecym 6487
gene id: 931890:Ecym_6487
uniprot id: G8JUS5
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase C1 family.
messages: Cytoplasm
messages: Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity.
messages: Homohexamer. Binds to nucleic acids. Binds single-stranded DNA and RNA with higher affinity than double-stranded DNA.
messages: Mitochondrion
messages: The normal physiological role of the enzyme is unknown, but it is not essential for the viability of yeast cells. Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. Acts as a repressor in the GAL4 regulatory system, but this does not require either the peptidase or nucleic acid-binding activities.

931890:Ecym 2014
gene id: 931890:Ecym_2014
uniprot id: G8JNX3
names: Domain
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DHHC palmitoyltransferase family.
messages: Membrane
messages: The DHHC domain is required for palmitoyltransferase activity.

931890:Ecym 5425
gene id: 931890:Ecym_5425
uniprot id: I6NDN7
names: Similarity
messages: Belongs to the TRAPP small subunits family. BET3 subfamily.

931890:Ecym 7224
gene id: 931890:Ecym_7224
uniprot id: G8JW55
names: Function
names: Similarity
names: Subunit
messages: Belongs to the casein kinase 2 subunit beta family.
messages: Regulatory subunit of casein kinase II/CK2 (By similarity). As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine.
messages: Tetramer of two alpha and two beta subunits.

931890:Ecym 7480
gene id: 931890:Ecym_7480
uniprot id: G8JWT2
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 6444
gene id: 931890:Ecym_6444
uniprot id: G8JUN5
names: Caution
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NnrE/AIBP family.
messages: Binds 1 potassium ion per subunit.
messages: Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.
messages: Cytoplasm
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Mitochondrion

931890:Ecym 5311
gene id: 931890:Ecym_5311
uniprot id: I6NDD0
names: Similarity
messages: Belongs to the PPase family.

931890:Ecym 7332
gene id: 931890:Ecym_7332
uniprot id: G8JWE9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the YPI1 family.
messages: Nucleus
messages: Regulator of type 1 phosphatases which maintains protein phosphatase activity under strict control.

931890:Ecym 5658
gene id: 931890:Ecym_5658
uniprot id: I6NE99
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit C family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm

931890:Ecym 7039
gene id: 931890:Ecym_7039
uniprot id: G8JVN0
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the PIGC family.
messages: Membrane

931890:Ecym 3007
gene id: 931890:Ecym_3007
uniprot id: G8JQV7
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2076
gene id: 931890:Ecym_2076
uniprot id: G8JPI3
names: Subcellular Location Annotation
messages: Peroxisome membrane

931890:Ecym 2440
gene id: 931890:Ecym_2440
uniprot id: G8JPB2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the STAM family.
messages: Endosome membrane

931890:Ecym 2249
gene id: 931890:Ecym_2249
uniprot id: G8JPP0
names: Similarity
messages: Belongs to the class-I DAHP synthase family.

931890:Ecym 4687
gene id: 931890:Ecym_4687
uniprot id: G8JSI6
names: Function
names: Similarity
messages: Belongs to the peroxiredoxin family. Prx6 subfamily.
messages: Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.

931890:Ecym 1122
gene id: 931890:Ecym_1122
uniprot id: G8JMM1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the GPI inositol-deacylase family.
messages: Endoplasmic reticulum membrane
messages: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins.

931890:Ecym 5001
gene id: 931890:Ecym_5001
uniprot id: I6NCL2
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 8161
gene id: 931890:Ecym_8161
uniprot id: G8JX74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peroxin-3 family.
messages: Membrane
messages: Peroxisome membrane

931890:Ecym 3567
gene id: 931890:Ecym_3567
uniprot id: G8JQQ4
names: Similarity
messages: Belongs to the GDA1/CD39 NTPase family.

931890:Ecym 3093
gene id: 931890:Ecym_3093
uniprot id: G8JR33
names: Function
names: Similarity
messages: Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
messages: This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

931890:Ecym 4551
gene id: 931890:Ecym_4551
uniprot id: G8JU83
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MDM31/MDM32 family.
messages: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 6008
gene id: 931890:Ecym_6008
uniprot id: G8JUT7
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the peptidase T1B family.
messages: Cytoplasm
messages: Non-catalytic component of the proteasome.
messages: Nucleus

931890:Ecym 3023
gene id: 931890:Ecym_3023
uniprot id: G8JQX0
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Aminocarboxypropyltransferase that catalyzes the aminocarboxypropyl transfer on pseudouridine at position 1191 (Psi1191) in 18S rRNA. It constitutes the last step in biosynthesis of the hypermodified N1-methyl-N3-(3-amino-3-carboxypropyl) pseudouridine (m1acp3-Psi) conserved in eukaryotic 18S rRNA.
messages: Belongs to the TDD superfamily. TSR3 family.
messages: Cytoplasm
messages: Nucleus

931890:Ecym 8405
gene id: 931890:Ecym_8405
uniprot id: G8JXV1
names: Similarity
messages: Belongs to the trans-sulfuration enzymes family.

931890:Ecym 2009
gene id: 931890:Ecym_2009
uniprot id: G8JNF9
names: Function
names: Similarity
messages: Belongs to the DMRL synthase family.
messages: Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.

931890:Ecym 8196
gene id: 931890:Ecym_8196
uniprot id: G8JXA7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TUBGCP family.
messages: microtubule organizing center

931890:Ecym 8183
gene id: 931890:Ecym_8183
uniprot id: G8JX95
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the FIT family. Yeast FIT2A/YFT2 subfamily.
messages: Endoplasmic reticulum membrane
messages: Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Preferentially hydrolyzes unsaturated long-chain acyl-CoA substrates in the endoplasmic reticulum (ER) lumen. This catalytic activity is required for maintaining ER structure and for lipid droplets (LDs) biogenesis, which are lipid storage organelles involved in maintaining lipid and energy homeostasis. May directly bind to diacylglycerol (DAGs) and triacylglycerol, which is also important for LD biogenesis. May support directional budding of nacent LDs from the ER into the cytosol by reducing DAG levels at sites of LD formation. May play a role in the regulation of cell morphology and cytoskeletal organization). Involved in phospholipid biosynthesis.
messages: Membrane

931890:Ecym 6303
gene id: 931890:Ecym_6303
uniprot id: G8JUA3
names: Similarity
messages: Belongs to the helicase family. SKI2 subfamily.

931890:Ecym 3398
gene id: 931890:Ecym_3398
uniprot id: G8JRW6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the peptidase S26B family.
messages: Catalytic component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity). Specifically cleaves N-terminal signal peptides that contain a hydrophobic alpha-helix (h-region) shorter than 18-20 amino acids.
messages: Component of the signal peptidase complex (SPC) composed of a catalytic subunit SEC11 and three accessory subunits SPC1, SPC2 and SPC3 (By similarity). The complex induces a local thinning of the ER membrane which is used to measure the length of the signal peptide (SP) h-region of protein substrates. This ensures the selectivity of the complex towards h-regions shorter than 18-20 amino acids (By similarity). SPC associates with the translocon complex.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 8229
gene id: 931890:Ecym_8229
uniprot id: G8JXE0
names: Similarity
messages: Belongs to the GHMP kinase family. Homoserine kinase subfamily.

931890:Ecym 4071
gene id: 931890:Ecym_4071
uniprot id: G8JSZ8
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the eIF-3 subunit G family.
messages: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
messages: Cytoplasm
messages: RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA.

931890:Ecym 6250
gene id: 931890:Ecym_6250
uniprot id: G8JVF3
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the MRE11/RAD32 family.
messages: Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
messages: Nucleus

931890:Ecym 7143
gene id: 931890:Ecym_7143
uniprot id: G8JVX7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family.
messages: Membrane

931890:Ecym 3367
gene id: 931890:Ecym_3367
uniprot id: G8JRT5
names: Cofactor
names: Similarity
messages: Belongs to the chorismate synthase family.
messages: Reduced FMN (FMNH(2)).

931890:Ecym 2213
gene id: 931890:Ecym_2213
uniprot id: G8JP57
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 3124
gene id: 931890:Ecym_3124
uniprot id: G8JR59
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the Mediator complex subunit 4 family.
messages: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
messages: Component of the Mediator complex.
messages: Nucleus

931890:Ecym 1109
gene id: 931890:Ecym_1109
uniprot id: G8JMK9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the eukaryotic RPA49/POLR1E RNA polymerase subunit family.
messages: nucleolus

931890:Ecym 1536
gene id: 931890:Ecym_1536
uniprot id: G8JMU1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the BOS1 family.
messages: Golgi apparatus membrane
messages: Membrane
messages: SNARE required for protein transport between the ER and the Golgi complex.

931890:Ecym 7189
gene id: 931890:Ecym_7189
uniprot id: G8JW22
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
messages: Membrane

931890:Ecym 3192
gene id: 931890:Ecym_3192
uniprot id: G8JRC2
names: Similarity
messages: Belongs to the ATPase delta chain family.

931890:Ecym 3606
gene id: 931890:Ecym_3606
uniprot id: G8JQT5
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 4548
gene id: 931890:Ecym_4548
uniprot id: G8JU80
names: Similarity
messages: Belongs to the AAA ATPase family.

931890:Ecym 8157
gene id: 931890:Ecym_8157
uniprot id: G8JX70
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the EROs family.
messages: Endoplasmic reticulum membrane
messages: May function both as a monomer and a homodimer.

931890:Ecym 1283
gene id: 931890:Ecym_1283
uniprot id: G8JN58
names: Similarity
messages: Belongs to the bacterial ribosomal protein bL32 family.

931890:Ecym 1106
gene id: 931890:Ecym_1106
uniprot id: G8JMK6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the mitochondrion-specific ribosomal protein mL46 family.
messages: Mitochondrion

931890:Ecym 4776
gene id: 931890:Ecym_4776
uniprot id: G8JSR6
names: Similarity
messages: Belongs to the class-I aminoacyl-tRNA synthetase family.

931890:Ecym 4247
gene id: 931890:Ecym_4247
uniprot id: G8JTF9
names: Function
messages: Hydrolyzes fatty acids from S-acylated cysteine residues in proteins with a strong preference for palmitoylated G-alpha proteins over other acyl substrates. Mediates the deacylation of G-alpha proteins such as GPA1 in vivo, but has weak or no activity toward palmitoylated Ras proteins. Has weak lysophospholipase activity in vitro; however such activity may not exist in vivo.

931890:Ecym 2672
gene id: 931890:Ecym_2672
uniprot id: G8JNV7
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 7267
gene id: 931890:Ecym_7267
uniprot id: G8JW96
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the short-chain dehydrogenases/reductases (SDR) family.
messages: Peroxisome

931890:Ecym 2619
gene id: 931890:Ecym_2619
uniprot id: G8JQJ9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the CPSF4/YTH1 family.
messages: Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
messages: Nucleus

931890:Ecym 2823
gene id: 931890:Ecym_2823
uniprot id: G8JQF6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.
messages: Membrane

931890:Ecym 8211
gene id: 931890:Ecym_8211
uniprot id: G8JXC2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TCP-1 chaperonin family.
messages: Cytoplasm

931890:Ecym 2275
gene id: 931890:Ecym_2275
uniprot id: G8JPR6
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the DASH complex DAD3 family.
messages: Nucleus
messages: kinetochore
messages: spindle

931890:Ecym 5323
gene id: 931890:Ecym_5323
uniprot id: I6NDE0
names: Function
names: Similarity
messages: Belongs to the REXO4 family.
messages: Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs.

931890:Ecym 2124
gene id: 931890:Ecym_2124
uniprot id: G8JNG1
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ROT1 family.
messages: Endoplasmic reticulum membrane
messages: Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies.

931890:Ecym 2466
gene id: 931890:Ecym_2466
uniprot id: G8JPT4
names: Similarity
messages: Belongs to the MUB1/samB family.

931890:Ecym 1395
gene id: 931890:Ecym_1395
uniprot id: G8JM54
names: Similarity
messages: Belongs to the DEAD box helicase family.

931890:Ecym 2397
gene id: 931890:Ecym_2397
uniprot id: G8JNR2
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CHEK2 subfamily.
messages: Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5.
messages: Nucleus

931890:Ecym 3147
gene id: 931890:Ecym_3147
uniprot id: G8JR81
names: Cofactor
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the HAM1 NTPase family.
messages: Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).
messages: Cytoplasm
messages: Homodimer.
messages: Nucleus
messages: Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.

931890:Ecym 3262
gene id: 931890:Ecym_3262
uniprot id: G8JRI6
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the cytochrome c oxidase VIIc family.
messages: Component of the cytochrome c oxidase (complex IV, CIV), a multisubunit enzyme composed of a catalytic core of 3 subunits and several supernumerary subunits. The complex exists as a monomer or a dimer and forms supercomplexes (SCs) in the inner mitochondrial membrane with ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII).
messages: Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Electrons originating from reduced cytochrome c in the intermembrane space (IMS) are transferred via the dinuclear copper A center (CU(A)) of subunit 2 and heme A of subunit 1 to the active site in subunit 1, a binuclear center (BNC) formed by heme A3 and copper B (CU(B)). The BNC reduces molecular oxygen to 2 water molecules using 4 electrons from cytochrome c in the IMS and 4 protons from the mitochondrial matrix.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2258
gene id: 931890:Ecym_2258
uniprot id: G8JPP9
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat SEC13 family.
messages: Membrane
messages: nuclear pore complex

931890:Ecym 6248
gene id: 931890:Ecym_6248
uniprot id: G8JVF1
names: Similarity
messages: Belongs to the peptidase C19 family.

931890:Ecym 6275
gene id: 931890:Ecym_6275
uniprot id: G8JVH7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the WD repeat UTP18 family.
messages: nucleolus

931890:Ecym 3498
gene id: 931890:Ecym_3498
uniprot id: G8JS59
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eS24 family.

931890:Ecym 2458
gene id: 931890:Ecym_2458
uniprot id: G8JPC7
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the VPS11 family.
messages: Component of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex. Component of the class C core vacuole/endosome tethering (CORVET) complex.
messages: Vacuole membrane

931890:Ecym 5030
gene id: 931890:Ecym_5030
uniprot id: I6NCN8
names: Caution
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERGIC family.
messages: Endoplasmic reticulum membrane
messages: Endoplasmic reticulum-Golgi intermediate compartment membrane
messages: Golgi apparatus membrane
messages: Lacks conserved residue(s) required for the propagation of feature annotation.
messages: Plays a role in transport between endoplasmic reticulum and Golgi.

931890:Ecym 8056
gene id: 931890:Ecym_8056
uniprot id: G8JWX8
names: Similarity
messages: Belongs to the universal ribosomal protein uL29 family.

931890:Ecym 5608
gene id: 931890:Ecym_5608
uniprot id: I6NE52
names: Subcellular Location Annotation
messages: nuclear pore complex

931890:Ecym 2183
gene id: 931890:Ecym_2183
uniprot id: G8JP27
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1200
gene id: 931890:Ecym_1200
uniprot id: G8JMY4
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
messages: cytoskeleton

931890:Ecym 3616
gene id: 931890:Ecym_3616
uniprot id: G8JQU3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.
messages: Bud neck

931890:Ecym 3217
gene id: 931890:Ecym_3217
uniprot id: G8JRE5
names: Similarity
messages: Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.

931890:Ecym 3145
gene id: 931890:Ecym_3145
uniprot id: G8JR79
names: Function
names: Similarity
names: Subunit
messages: Belongs to the PSMG2 family.
messages: Component of the 20S proteasome chaperone.
messages: Involved in 20S proteasome assembly.

931890:Ecym 3499
gene id: 931890:Ecym_3499
uniprot id: G8JS60
names: Similarity
messages: Belongs to the YOS1 family.

931890:Ecym 1140
gene id: 931890:Ecym_1140
uniprot id: G8JMN7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COG8 family.
messages: Membrane

931890:Ecym 2424
gene id: 931890:Ecym_2424
uniprot id: G8JP97
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Belongs to the CWC16 family. YJU2 subfamily.
messages: Component of the spliceosome. Present in the activated B complex, the catalytically activated B* complex which catalyzes the branching, the catalytic step 1 C complex catalyzing the exon ligation, and the postcatalytic P complex containing the ligated exons (mRNA) and the excised lariat intron.
messages: Nucleus
messages: Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA. Plays a role (via N-terminus) in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. Further stabilizes spliceosome conformation for 3'-splice site docking (via C-terminus) promoting exon ligation.

931890:Ecym 3048
gene id: 931890:Ecym_3048
uniprot id: G8JQZ2
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HRD1 family.
messages: Endoplasmic reticulum membrane
messages: Membrane

931890:Ecym 2412
gene id: 931890:Ecym_2412
uniprot id: G8JP86
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the NOP53 family.
messages: May play a role in ribosome biogenesis.
messages: nucleolus
messages: nucleoplasm

931890:Ecym 8360
gene id: 931890:Ecym_8360
uniprot id: G8JXQ9
names: Function
names: Similarity
names: Subcellular Location Annotation
names: Subunit
messages: Acts as component of the MCM2-7 complex (MCM complex) which is the replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
messages: Belongs to the MCM family.
messages: Component of the MCM2-7 complex.
messages: Nucleus

931890:Ecym 4383
gene id: 931890:Ecym_4383
uniprot id: G8JTT5
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HisA/HisF family.
messages: Cytoplasm

931890:Ecym 6414
gene id: 931890:Ecym_6414
uniprot id: G8JUK6
names: Similarity
messages: Belongs to the APC1 family.

931890:Ecym 3391
gene id: 931890:Ecym_3391
uniprot id: G8JRV9
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATPase d subunit family.
messages: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
messages: Mitochondrion inner membrane

931890:Ecym 6299
gene id: 931890:Ecym_6299
uniprot id: G8JU99
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the TIM54 family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 8280
gene id: 931890:Ecym_8280
uniprot id: G8JXI8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the COX16 family.
messages: Membrane

931890:Ecym 7048
gene id: 931890:Ecym_7048
uniprot id: G8JVN9
names: Subcellular Location Annotation
messages: Nucleus

931890:Ecym 1067
gene id: 931890:Ecym_1067
uniprot id: G8JMB6
names: Function
names: Similarity
messages: Belongs to the eukaryotic ribosomal protein eL37 family.
messages: Component of the large ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

931890:Ecym 7200
gene id: 931890:Ecym_7200
uniprot id: G8JW33
names: Similarity
messages: Belongs to the universal ribosomal protein uS7 family.

931890:Ecym 6210
gene id: 931890:Ecym_6210
uniprot id: G8JVB3
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the cytochrome c oxidase subunit 6A family.
messages: Membrane
messages: Mitochondrion inner membrane

931890:Ecym 2340
gene id: 931890:Ecym_2340
uniprot id: G8JQ74
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the EMP24/GP25L family.
messages: Membrane

931890:Ecym 5053
gene id: 931890:Ecym_5053
uniprot id: I6NCQ2
names: Similarity
names: Subunit
messages: Belongs to the pyruvate kinase family.
messages: Homotetramer.

931890:Ecym 1049
gene id: 931890:Ecym_1049
uniprot id: G8JM98
names: Similarity
messages: Belongs to the RRP7 family.

931890:Ecym 5648
gene id: 931890:Ecym_5648
uniprot id: I6NE91
names: Cofactor
names: Similarity
messages: Binds 1 Mg(2+) ion per subunit.
messages: In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

931890:Ecym 6355
gene id: 931890:Ecym_6355
uniprot id: G8JUF1
names: Similarity
messages: Belongs to the ERT1/acuK family.

931890:Ecym 2208
gene id: 931890:Ecym_2208
uniprot id: G8JP52
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the HSF family.
messages: Nucleus

931890:Ecym 5153
gene id: 931890:Ecym_5153
uniprot id: I6NCY7
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the AIM18/AIM46 family.
messages: Mitochondrion

931890:Ecym 1063
gene id: 931890:Ecym_1063
uniprot id: G8JMB2
names: Cofactor
names: Function
names: Similarity
messages: Belongs to the AdoMet synthase family.
messages: Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate.
messages: Binds 2 magnesium ions per subunit. The magnesium ions interact primarily with the substrate.
messages: Catalyzes the formation of S-adenosylmethionine from methionine and ATP.

931890:Ecym 8097
gene id: 931890:Ecym_8097
uniprot id: G8JX17
names: Subcellular Location Annotation
messages: Membrane

931890:Ecym 2749
gene id: 931890:Ecym_2749
uniprot id: G8JPY5
names: Similarity
messages: Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.

931890:Ecym 1040
gene id: 931890:Ecym_1040
uniprot id: G8JM38
names: Function
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ATG22 family.
messages: Membrane
messages: Vacuolar effluxer which mediate the efflux of amino acids resulting from autophagic degradation. The release of autophagic amino acids allows the maintenance of protein synthesis and viability during nitrogen starvation.
messages: Vacuole membrane

931890:Ecym 4248
gene id: 931890:Ecym_4248
uniprot id: G8JTG0
names: Similarity
messages: Belongs to the VPS37 family.

931890:Ecym 3597
gene id: 931890:Ecym_3597
uniprot id: G8JQS8
names: Similarity
names: Subcellular Location Annotation
messages: Belongs to the ERG4/ERG24 family.
messages: Membrane

931890:Ecym 1409
gene id: 931890:Ecym_1409
uniprot id: G8JM66
names: Similarity
messages: Belongs to the glycosyltransferase 32 family.